|
|
Biological Process (BP): developmental growth involved in morphogenesis
(show info)
Gene Ontology (GO)
GO depicts three complementary biological concepts including Biological Process (BP), Molecular Function (MF) and Cellular Component (CC). The hierarchical structure of GO is organized as a directed acyclic graph (DAG) by viewing an individual term as a node and its relations to parental terms (allowing for multiple parents) as directed edges. To navigate this hierarchy, we display all parental GO terms to the current GO term of interest ordered by their shortest distances to the current term. Also, only direct children GO terms of the current GO term are listed.
Structural Classification of Proteins (SCOP)
SCOP classifies evolutionary-related domains into Superfamily level and Family level. Accordingly, we have generated the domain-centric GO annotations for each of the three concepts at each of the two domain levels.
Structural Domain Functional Ontology (SDFO)
As domain-centric ontology, SDFO only refers to those GO terms which are the most informative to annotate SCOP domains.
GO annotations for SCOP domains
For details, please visit Documentation: GO annotations for SCOP domains. Therein, we provide several relevant files ( Data Availability) for the download. It includes two mapping results: Domain2GO supported by both, and Domain2GO supported only by all. For each mapping result, the ontology and annotation files are available. The annotation (i.e., Domain2GO_supported_by_both.txt) and the corresponding ontology (i.e., SDFO.both.txt) are suitable for small-scale studies (high-quality, and BROWSABLE BELOW), while the annotation (i.e., Domain2GO_supported_only_by_all.txt) and the corresponding ontology (i.e., SDFO.all.txt) for large-scale studies (high-coverage, like functional enrichment analysis).
Supra-domain Functional Ontology (SPFO)
As an extension, SPFO includes those GO terms which are the most informative to annotate supra-domains and individual SCOP domains at the Superfamily level.
GO annotations for Supra-domains
For details, please visit Documentation: GO annotations for Supra-domains. Therein, we provide several relevant files ( Data Availability) for the download, including a annotation file (i.e., SP2GO.txt) and an ontology (i.e., SPFO.txt). For the sake of being browsable, listed below are those supra-domains (single, dual, triple, quad).
Jump to [ Top · GO Hierarchy · Superfamily · Family · Supra-domain ]
Root: GO Hierarchy Containing Three Sub-Ontologies (BP, MF, CC)
Jump to [ Top · GO Hierarchy · Superfamily · Family · Supra-domain ]
Superfamily(show details)
Superfamily domains annotated to this GO term (Not in SDFO)
Highlighted in gray are those with either FDR_singleton>0.001 or FDR_all>0.001
Jump to [ Top · GO Hierarchy · Superfamily · Family · Supra-domain ]
Family(show details)
Family domains annotated to this GO term (Not in SDFO)
Highlighted in gray are those with either FDR_singleton>0.001 or FDR_all>0.001
Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this GO term
 |
Plot tree as:
| |
Download Newick format tree:
|
(show help)
Trees by TreeVector
A presence/absence matrix is generated using protein domains and supradomains
for all genomes in SUPERFAMILY. The RAxML
software is used to produce a single, large tree topology using
heuristic parsimony methods. Genome combinations, or specific clades, can be displayed as
if individual trees had been produced. However, this data is extracted from the single
large tree. This produces a higher quality topology than if the trees had been produced
on their own, and allows the trees to be displayed instantly.
Jump to [ Top · GO Hierarchy · Superfamily · Family · Supra-domain ]
Supra-domain (including individual superfamily)
(show details)
Supra-domains annotated to this GO term (SPFO level: Informative)
Highlighted in gray are those with FDR>0.001
| Supra-domain (Single) |
FDR (all) |
Annotation (direct or inherited) |
| Immunoglobulin | 0 | DIRECT |
| CAPPD, an extracellular domain of amyloid beta A4 protein | 3.599e-15 | DIRECT |
| Amyloid beta a4 protein copper binding domain (domain 2) | 3.765e-14 | DIRECT |
| A heparin-binding domain | 3.765e-14 | DIRECT |
| TSP type-3 repeat | 1.881e-12 | DIRECT |
| BPTI-like | 3.354e-11 | DIRECT |
| Protein kinase-like (PK-like) | 8.873e-11 | DIRECT |
| Doublecortin (DC) | 3.506e-09 | DIRECT |
| Fibronectin type III | 2.524e-07 | DIRECT |
| Plant invertase/pectin methylesterase inhibitor | 5.404e-07 | DIRECT |
| L27 domain | 3.248e-06 | DIRECT |
| Assembly domain of cartilage oligomeric matrix protein | 4.031e-06 | DIRECT |
| Invertebrate chitin-binding proteins | 4.498e-06 | DIRECT |
| Pectin lyase-like | 5.75e-06 | DIRECT |
| PDZ domain-like | 9.338e-06 | DIRECT |
| Glycoside hydrolase/deacetylase | 5.856e-05 | DIRECT |
| Concanavalin A-like lectins/glucanases | 0.000184 | DIRECT |
| L domain-like | 0.0004232 | DIRECT |
| Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain | 0.0005411 | DIRECT |
| DBL homology domain (DH-domain) | 0.05294 | INHERITED FROM: cell elongation involved in imaginal disc-derived wing morphogenesis |
| Snake toxin-like | 0.2961 | INHERITED FROM: cell elongation involved in imaginal disc-derived wing morphogenesis |
| SMAD MH1 domain | 0.4828 | INHERITED FROM: cell elongation involved in imaginal disc-derived wing morphogenesis |
| Cysteine-rich domain | 0.52 | INHERITED FROM: cell elongation involved in imaginal disc-derived wing morphogenesis |
| PH domain-like | 0.9907 | INHERITED FROM: cell elongation involved in imaginal disc-derived wing morphogenesis |
| EGF/Laminin | 0.018 | INHERITED FROM: axis elongation involved in somitogenesis || mammary duct terminal end bud growth || endochondral bone growth |
| beta-beta-alpha zinc fingers | 1 | INHERITED FROM: ureteric bud invasion || convergent extension involved in axis elongation |
| 4-helical cytokines | 0.001447 | INHERITED FROM: mammary duct terminal end bud growth |
| Growth factor receptor domain | 0.8741 | INHERITED FROM: mammary duct terminal end bud growth |
| Nuclear receptor ligand-binding domain | 0.004113 | INHERITED FROM: epithelial cell proliferation involved in mammary gland duct elongation || prostate gland morphogenetic growth || branch elongation involved in mammary gland duct branching || branch elongation of an epithelium || growth plate cartilage development || endochondral bone growth |
| lambda repressor-like DNA-binding domains | 0.1321 | INHERITED FROM: ureteric bud elongation |
| KRAB domain (Kruppel-associated box) | 0.6389 | INHERITED FROM: convergent extension involved in axis elongation |
| RNI-like | 0.2089 | INHERITED FROM: root hair elongation || cell tip growth |
| Cupredoxins | 0.02651 | INHERITED FROM: root hair elongation |
| Aquaporin-like | 0.02774 | INHERITED FROM: root hair elongation |
| Ankyrin repeat | 0.002327 | INHERITED FROM: axon extension |
| HD-domain/PDEase-like | 0.08713 | INHERITED FROM: axon extension |
| Glucocorticoid receptor-like (DNA-binding domain) | 0.654 | INHERITED FROM: imaginal disc-derived wing expansion || epithelial cell proliferation involved in mammary gland duct elongation || branch elongation involved in mammary gland duct branching || growth plate cartilage development || endochondral bone growth |
| Homeodomain-like | 1 | INHERITED FROM: elongation of arista core |
| LDL receptor-like module | 0.01631 | INHERITED FROM: dorsal trunk growth, open tracheal system || axis elongation involved in somitogenesis |
| PGBD-like | 0.113 | INHERITED FROM: dorsal trunk growth, open tracheal system |
| Hemopexin-like domain | 0.1275 | INHERITED FROM: dorsal trunk growth, open tracheal system |
| Metalloproteases ("zincins"), catalytic domain | 0.8881 | INHERITED FROM: dorsal trunk growth, open tracheal system |
| SH3-domain | 1 | INHERITED FROM: dorsal trunk growth, open tracheal system |
| Adenine nucleotide alpha hydrolases-like | 0.01828 | INHERITED FROM: pollen tube growth || cell tip growth |
| Cullin repeat-like | 0.08179 | INHERITED FROM: pollen tube growth || cell tip growth |
| SMAD/FHA domain | 0.04345 | INHERITED FROM: unidimensional cell growth || cell elongation involved in imaginal disc-derived wing morphogenesis || dorsal closure, elongation of leading edge cells |
| Regulator of G-protein signaling, RGS | 0.02651 | INHERITED FROM: unidimensional cell growth || cell elongation involved in imaginal disc-derived wing morphogenesis |
| Tubulin C-terminal domain-like | 0.001746 | INHERITED FROM: unidimensional cell growth || root hair elongation || cell tip growth |
| Tubulin nucleotide-binding domain-like | 0.003956 | INHERITED FROM: unidimensional cell growth || root hair elongation || cell tip growth |
| Phospholipase A2, PLA2 | 0.002728 | INHERITED FROM: unidimensional cell growth || pollen tube growth || cell tip growth |
| SAICAR synthase-like | 0.005291 | INHERITED FROM: unidimensional cell growth || pollen tube growth || cell tip growth |
| SRF-like | 0.02916 | INHERITED FROM: unidimensional cell growth || pollen tube growth || cell tip growth |
| Heme-dependent peroxidases | 0.07233 | INHERITED FROM: unidimensional cell growth |
| Ubiquitin-like | 0.01658 | INHERITED FROM: dorsal closure, elongation of leading edge cells || axon extension |
| TSP-1 type 1 repeat | 0.3161 | INHERITED FROM: growth plate cartilage development || endochondral bone growth |
| FnI-like domain | 0.2395 | INHERITED FROM: endochondral bone growth |
| YWTD domain | 0.2395 | INHERITED FROM: axis elongation || axis elongation involved in somitogenesis |
| HMG-box | 0.7123 | INHERITED FROM: axis elongation || prostate gland morphogenetic growth || epithelial cell proliferation involved in prostatic bud elongation || primary prostatic bud elongation |
| Cytokine | 0.001052 | INHERITED FROM: axis elongation || branch elongation of an epithelium || ureteric bud elongation || branch elongation involved in ureteric bud branching |
| Hedgehog/intein (Hint) domain | 0.02201 | INHERITED FROM: axis elongation || prostate epithelial cord elongation || bud outgrowth involved in lung branching || prostate gland morphogenetic growth || primary prostatic bud elongation |
| Hedgehog/DD-peptidase | 0.02201 | INHERITED FROM: axis elongation || prostate epithelial cord elongation || bud outgrowth involved in lung branching || prostate gland morphogenetic growth || primary prostatic bud elongation |
| Fibrinogen C-terminal domain-like | 0.2103 | INHERITED FROM: axis elongation || bud outgrowth involved in lung branching || branch elongation of an epithelium |
| TIMP-like | 0.02255 | INHERITED FROM: axis elongation || convergent extension involved in axis elongation |
| HLH, helix-loop-helix DNA-binding domain | 1 | INHERITED FROM: growth involved in heart morphogenesis |
(show details)
Supra-domains annotated to this GO term (SPFO level: Informative)
Highlighted in gray are those with FDR>0.001
| Supra-domain (Duplex) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
48097,57889 48097 - Regulator of G-protein signaling, RGS 57889 - Cysteine-rich domain | 0 | DIRECT |
49265,48726 49265 - Fibronectin type III 48726 - Immunoglobulin | 0 | DIRECT |
48726,49265 48726 - Immunoglobulin 49265 - Fibronectin type III | 0 | DIRECT |
109640,109640 109640 - KRAB domain (Kruppel-associated box) 109640 - KRAB domain (Kruppel-associated box) | 0 | DIRECT |
48726,48726 48726 - Immunoglobulin 48726 - Immunoglobulin | 0 | DIRECT |
57362,109843 57362 - BPTI-like 109843 - CAPPD, an extracellular domain of amyloid beta A4 protein | 2.693e-14 | DIRECT |
56491,89811 56491 - A heparin-binding domain 89811 - Amyloid beta a4 protein copper binding domain (domain 2) | 3.765e-14 | DIRECT |
103647,49899 103647 - TSP type-3 repeat 49899 - Concanavalin A-like lectins/glucanases | 1.881e-12 | DIRECT |
57625,57424 57625 - Invertebrate chitin-binding proteins 57424 - LDL receptor-like module | 3.101e-12 | DIRECT |
57424,88713 57424 - LDL receptor-like module 88713 - Glycoside hydrolase/deacetylase | 3.101e-12 | DIRECT |
50156,52799 50156 - PDZ domain-like 52799 - (Phosphotyrosine protein) phosphatases II | 1.615e-10 | DIRECT |
103647,103647 103647 - TSP type-3 repeat 103647 - TSP type-3 repeat | 1.89e-09 | DIRECT |
54236,49879 54236 - Ubiquitin-like 49879 - SMAD/FHA domain | 3.47e-09 | DIRECT |
89837,89837 89837 - Doublecortin (DC) 89837 - Doublecortin (DC) | 3.506e-09 | DIRECT |
101288,50156 101288 - L27 domain 50156 - PDZ domain-like | 1.412e-06 | DIRECT |
82895,57196 82895 - TSP-1 type 1 repeat 57196 - EGF/Laminin | 7.79e-06 | DIRECT |
54236,50729 54236 - Ubiquitin-like 50729 - PH domain-like | 7.79e-06 | DIRECT |
57603,82895 57603 - FnI-like domain 82895 - TSP-1 type 1 repeat | 7.79e-06 | DIRECT |
52058,56112 52058 - L domain-like 56112 - Protein kinase-like (PK-like) | 6.211e-05 | DIRECT |
57184,49899 57184 - Growth factor receptor domain 49899 - Concanavalin A-like lectins/glucanases | 9.438e-05 | DIRECT |
63501,50242 63501 - Frizzled cysteine-rich domain 50242 - TIMP-like | 0.0009674 | DIRECT |
48065,50729 48065 - DBL homology domain (DH-domain) 50729 - PH domain-like | 0.04665 | INHERITED FROM: cell elongation involved in imaginal disc-derived wing morphogenesis |
57667,57667 57667 - beta-beta-alpha zinc fingers 57667 - beta-beta-alpha zinc fingers | 1 | INHERITED FROM: ureteric bud invasion || convergent extension involved in axis elongation |
49899,57196 49899 - Concanavalin A-like lectins/glucanases 57196 - EGF/Laminin | 0.001958 | INHERITED FROM: mammary duct terminal end bud growth |
57196,57184 57196 - EGF/Laminin 57184 - Growth factor receptor domain | 0.02985 | INHERITED FROM: mammary duct terminal end bud growth |
57196,49899 57196 - EGF/Laminin 49899 - Concanavalin A-like lectins/glucanases | 0.1651 | INHERITED FROM: mammary duct terminal end bud growth |
57196,57196 57196 - EGF/Laminin 57196 - EGF/Laminin | 0.1903 | INHERITED FROM: mammary duct terminal end bud growth |
57716,48508 57716 - Glucocorticoid receptor-like (DNA-binding domain) 48508 - Nuclear receptor ligand-binding domain | 0.004398 | INHERITED FROM: epithelial cell proliferation involved in mammary gland duct elongation || prostate gland morphogenetic growth || branch elongation involved in mammary gland duct branching || branch elongation of an epithelium || growth plate cartilage development || endochondral bone growth |
49265,49265 49265 - Fibronectin type III 49265 - Fibronectin type III | 1 | INHERITED FROM: bud outgrowth involved in lung branching || branch elongation of an epithelium |
47031,50729 47031 - Second domain of FERM 50729 - PH domain-like | 0.5907 | INHERITED FROM: axon extension involved in axon guidance |
48403,48403 48403 - Ankyrin repeat 48403 - Ankyrin repeat | 0.00132 | INHERITED FROM: axon extension |
50729,50044 50729 - PH domain-like 50044 - SH3-domain | 0.0121 | INHERITED FROM: axon extension |
57716,57716 57716 - Glucocorticoid receptor-like (DNA-binding domain) 57716 - Glucocorticoid receptor-like (DNA-binding domain) | 1 | INHERITED FROM: imaginal disc-derived wing expansion |
55486,50923 55486 - Metalloproteases ("zincins"), catalytic domain 50923 - Hemopexin-like domain | 0.05309 | INHERITED FROM: dorsal trunk growth, open tracheal system |
50156,50044 50156 - PDZ domain-like 50044 - SH3-domain | 0.1105 | INHERITED FROM: dorsal trunk growth, open tracheal system |
47090,55486 47090 - PGBD-like 55486 - Metalloproteases ("zincins"), catalytic domain | 0.113 | INHERITED FROM: dorsal trunk growth, open tracheal system |
50044,52540 50044 - SH3-domain 52540 - P-loop containing nucleoside triphosphate hydrolases | 0.2577 | INHERITED FROM: dorsal trunk growth, open tracheal system |
82185,82185 82185 - Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain 82185 - Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain | 0.001929 | INHERITED FROM: cell tip growth |
52490,55307 52490 - Tubulin nucleotide-binding domain-like 55307 - Tubulin C-terminal domain-like | 0.001404 | INHERITED FROM: unidimensional cell growth || root hair elongation || cell tip growth |
52047,52058 52047 - RNI-like 52058 - L domain-like | 0.007044 | INHERITED FROM: unidimensional cell growth || root hair elongation || cell tip growth |
82895,82895 82895 - TSP-1 type 1 repeat 82895 - TSP-1 type 1 repeat | 0.1008 | INHERITED FROM: growth plate cartilage development || endochondral bone growth |
57196,57424 57196 - EGF/Laminin 57424 - LDL receptor-like module | 0.001595 | INHERITED FROM: axis elongation || axis elongation involved in somitogenesis |
63825,57196 63825 - YWTD domain 57196 - EGF/Laminin | 0.05522 | INHERITED FROM: axis elongation || axis elongation involved in somitogenesis |
57424,57424 57424 - LDL receptor-like module 57424 - LDL receptor-like module | 0.3557 | INHERITED FROM: axis elongation || axis elongation involved in somitogenesis |
55166,51294 55166 - Hedgehog/DD-peptidase 51294 - Hedgehog/intein (Hint) domain | 0.02201 | INHERITED FROM: axis elongation || prostate epithelial cord elongation || bud outgrowth involved in lung branching || prostate gland morphogenetic growth || primary prostatic bud elongation |
49265,56496 49265 - Fibronectin type III 56496 - Fibrinogen C-terminal domain-like | 0.01661 | INHERITED FROM: axis elongation || bud outgrowth involved in lung branching || branch elongation of an epithelium |
| Supra-domain (Duplex) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
48097,57889 48097 - Regulator of G-protein signaling, RGS 57889 - Cysteine-rich domain | 0 | Direct |
49265,48726 49265 - Fibronectin type III 48726 - Immunoglobulin | 0 | Direct |
48726,49265 48726 - Immunoglobulin 49265 - Fibronectin type III | 0 | Direct |
109640,109640 109640 - KRAB domain (Kruppel-associated box) 109640 - KRAB domain (Kruppel-associated box) | 0 | Direct |
48726,48726 48726 - Immunoglobulin 48726 - Immunoglobulin | 0 | Direct |
57362,109843 57362 - BPTI-like 109843 - CAPPD, an extracellular domain of amyloid beta A4 protein | 2.693e-14 | Direct |
56491,89811 56491 - A heparin-binding domain 89811 - Amyloid beta a4 protein copper binding domain (domain 2) | 3.765e-14 | Direct |
103647,49899 103647 - TSP type-3 repeat 49899 - Concanavalin A-like lectins/glucanases | 1.881e-12 | Direct |
57625,57424 57625 - Invertebrate chitin-binding proteins 57424 - LDL receptor-like module | 3.101e-12 | Direct |
57424,88713 57424 - LDL receptor-like module 88713 - Glycoside hydrolase/deacetylase | 3.101e-12 | Direct |
50156,52799 50156 - PDZ domain-like 52799 - (Phosphotyrosine protein) phosphatases II | 1.615e-10 | Direct |
103647,103647 103647 - TSP type-3 repeat 103647 - TSP type-3 repeat | 1.89e-09 | Direct |
54236,49879 54236 - Ubiquitin-like 49879 - SMAD/FHA domain | 3.47e-09 | Direct |
89837,89837 89837 - Doublecortin (DC) 89837 - Doublecortin (DC) | 3.506e-09 | Direct |
101288,50156 101288 - L27 domain 50156 - PDZ domain-like | 1.412e-06 | Direct |
82895,57196 82895 - TSP-1 type 1 repeat 57196 - EGF/Laminin | 7.79e-06 | Direct |
54236,50729 54236 - Ubiquitin-like 50729 - PH domain-like | 7.79e-06 | Direct |
57603,82895 57603 - FnI-like domain 82895 - TSP-1 type 1 repeat | 7.79e-06 | Direct |
52058,56112 52058 - L domain-like 56112 - Protein kinase-like (PK-like) | 6.211e-05 | Direct |
57184,49899 57184 - Growth factor receptor domain 49899 - Concanavalin A-like lectins/glucanases | 9.438e-05 | Direct |
63501,50242 63501 - Frizzled cysteine-rich domain 50242 - TIMP-like | 0.0009674 | Direct |
48065,50729 48065 - DBL homology domain (DH-domain) 50729 - PH domain-like | 0.04665 | Inherited |
57667,57667 57667 - beta-beta-alpha zinc fingers 57667 - beta-beta-alpha zinc fingers | 1 | Inherited |
49899,57196 49899 - Concanavalin A-like lectins/glucanases 57196 - EGF/Laminin | 0.001958 | Inherited |
57196,57184 57196 - EGF/Laminin 57184 - Growth factor receptor domain | 0.02985 | Inherited |
57196,49899 57196 - EGF/Laminin 49899 - Concanavalin A-like lectins/glucanases | 0.1651 | Inherited |
57196,57196 57196 - EGF/Laminin 57196 - EGF/Laminin | 0.1903 | Inherited |
57716,48508 57716 - Glucocorticoid receptor-like (DNA-binding domain) 48508 - Nuclear receptor ligand-binding domain | 0.004398 | Inherited |
49265,49265 49265 - Fibronectin type III 49265 - Fibronectin type III | 1 | Inherited |
47031,50729 47031 - Second domain of FERM 50729 - PH domain-like | 0.5907 | Inherited |
48403,48403 48403 - Ankyrin repeat 48403 - Ankyrin repeat | 0.00132 | Inherited |
50729,50044 50729 - PH domain-like 50044 - SH3-domain | 0.0121 | Inherited |
57716,57716 57716 - Glucocorticoid receptor-like (DNA-binding domain) 57716 - Glucocorticoid receptor-like (DNA-binding domain) | 1 | Inherited |
55486,50923 55486 - Metalloproteases ("zincins"), catalytic domain 50923 - Hemopexin-like domain | 0.05309 | Inherited |
50156,50044 50156 - PDZ domain-like 50044 - SH3-domain | 0.1105 | Inherited |
47090,55486 47090 - PGBD-like 55486 - Metalloproteases ("zincins"), catalytic domain | 0.113 | Inherited |
50044,52540 50044 - SH3-domain 52540 - P-loop containing nucleoside triphosphate hydrolases | 0.2577 | Inherited |
82185,82185 82185 - Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain 82185 - Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain | 0.001929 | Inherited |
52490,55307 52490 - Tubulin nucleotide-binding domain-like 55307 - Tubulin C-terminal domain-like | 0.001404 | Inherited |
52047,52058 52047 - RNI-like 52058 - L domain-like | 0.007044 | Inherited |
82895,82895 82895 - TSP-1 type 1 repeat 82895 - TSP-1 type 1 repeat | 0.1008 | Inherited |
57196,57424 57196 - EGF/Laminin 57424 - LDL receptor-like module | 0.001595 | Inherited |
63825,57196 63825 - YWTD domain 57196 - EGF/Laminin | 0.05522 | Inherited |
57424,57424 57424 - LDL receptor-like module 57424 - LDL receptor-like module | 0.3557 | Inherited |
55166,51294 55166 - Hedgehog/DD-peptidase 51294 - Hedgehog/intein (Hint) domain | 0.02201 | Inherited |
49265,56496 49265 - Fibronectin type III 56496 - Fibrinogen C-terminal domain-like | 0.01661 | Inherited |
(show details)
Supra-domains annotated to this GO term (SPFO level: Informative)
Highlighted in gray are those with FDR>0.001
| Supra-domain (Triple) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
48726,48726,49265 48726 - Immunoglobulin 48726 - Immunoglobulin 49265 - Fibronectin type III | 0 | DIRECT |
49265,48726,49265 49265 - Fibronectin type III 48726 - Immunoglobulin 49265 - Fibronectin type III | 0 | DIRECT |
48726,48726,48726 48726 - Immunoglobulin 48726 - Immunoglobulin 48726 - Immunoglobulin | 0 | DIRECT |
57625,57424,88713 57625 - Invertebrate chitin-binding proteins 57424 - LDL receptor-like module 88713 - Glycoside hydrolase/deacetylase | 3.101e-12 | DIRECT |
103647,103647,49899 103647 - TSP type-3 repeat 103647 - TSP type-3 repeat 49899 - Concanavalin A-like lectins/glucanases | 1.89e-09 | DIRECT |
103647,103647,103647 103647 - TSP type-3 repeat 103647 - TSP type-3 repeat 103647 - TSP type-3 repeat | 1.818e-08 | DIRECT |
57184,49899,57196 57184 - Growth factor receptor domain 49899 - Concanavalin A-like lectins/glucanases 57196 - EGF/Laminin | 9.568e-07 | DIRECT |
57196,57184,49899 57196 - EGF/Laminin 57184 - Growth factor receptor domain 49899 - Concanavalin A-like lectins/glucanases | 1.937e-06 | DIRECT |
57603,82895,82895 57603 - FnI-like domain 82895 - TSP-1 type 1 repeat 82895 - TSP-1 type 1 repeat | 7.79e-06 | DIRECT |
82895,82895,57196 82895 - TSP-1 type 1 repeat 82895 - TSP-1 type 1 repeat 57196 - EGF/Laminin | 7.79e-06 | DIRECT |
101288,50156,50044 101288 - L27 domain 50156 - PDZ domain-like 50044 - SH3-domain | 0.0005411 | DIRECT |
57196,57196,57184 57196 - EGF/Laminin 57196 - EGF/Laminin 57184 - Growth factor receptor domain | 0.006738 | INHERITED FROM: mammary duct terminal end bud growth |
57667,57667,57667 57667 - beta-beta-alpha zinc fingers 57667 - beta-beta-alpha zinc fingers 57667 - beta-beta-alpha zinc fingers | 1 | INHERITED FROM: convergent extension involved in axis elongation |
48065,50729,50044 48065 - DBL homology domain (DH-domain) 50729 - PH domain-like 50044 - SH3-domain | 0.005592 | INHERITED FROM: axon extension |
57716,57716,57716 57716 - Glucocorticoid receptor-like (DNA-binding domain) 57716 - Glucocorticoid receptor-like (DNA-binding domain) 57716 - Glucocorticoid receptor-like (DNA-binding domain) | 0.1226 | INHERITED FROM: imaginal disc-derived wing expansion |
47090,55486,50923 47090 - PGBD-like 55486 - Metalloproteases ("zincins"), catalytic domain 50923 - Hemopexin-like domain | 0.05309 | INHERITED FROM: dorsal trunk growth, open tracheal system |
50156,50044,52540 50156 - PDZ domain-like 50044 - SH3-domain 52540 - P-loop containing nucleoside triphosphate hydrolases | 0.09167 | INHERITED FROM: dorsal trunk growth, open tracheal system |
82895,82895,82895 82895 - TSP-1 type 1 repeat 82895 - TSP-1 type 1 repeat 82895 - TSP-1 type 1 repeat | 0.003031 | INHERITED FROM: growth plate cartilage development || endochondral bone growth |
57196,57424,57424 57196 - EGF/Laminin 57424 - LDL receptor-like module 57424 - LDL receptor-like module | 0.001595 | INHERITED FROM: axis elongation || axis elongation involved in somitogenesis |
63825,57196,57424 63825 - YWTD domain 57196 - EGF/Laminin 57424 - LDL receptor-like module | 0.001595 | INHERITED FROM: axis elongation || axis elongation involved in somitogenesis |
57424,57424,57424 57424 - LDL receptor-like module 57424 - LDL receptor-like module 57424 - LDL receptor-like module | 0.3384 | INHERITED FROM: axis elongation || axis elongation involved in somitogenesis |
49265,49265,56496 49265 - Fibronectin type III 49265 - Fibronectin type III 56496 - Fibrinogen C-terminal domain-like | 0.001929 | INHERITED FROM: axis elongation || bud outgrowth involved in lung branching || branch elongation of an epithelium |
49265,49265,49265 49265 - Fibronectin type III 49265 - Fibronectin type III 49265 - Fibronectin type III | 0.3244 | INHERITED FROM: axis elongation || bud outgrowth involved in lung branching || branch elongation of an epithelium |
| Supra-domain (Triple) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
48726,48726,49265 48726 - Immunoglobulin 48726 - Immunoglobulin 49265 - Fibronectin type III | 0 | Direct |
49265,48726,49265 49265 - Fibronectin type III 48726 - Immunoglobulin 49265 - Fibronectin type III | 0 | Direct |
48726,48726,48726 48726 - Immunoglobulin 48726 - Immunoglobulin 48726 - Immunoglobulin | 0 | Direct |
57625,57424,88713 57625 - Invertebrate chitin-binding proteins 57424 - LDL receptor-like module 88713 - Glycoside hydrolase/deacetylase | 3.101e-12 | Direct |
103647,103647,49899 103647 - TSP type-3 repeat 103647 - TSP type-3 repeat 49899 - Concanavalin A-like lectins/glucanases | 1.89e-09 | Direct |
103647,103647,103647 103647 - TSP type-3 repeat 103647 - TSP type-3 repeat 103647 - TSP type-3 repeat | 1.818e-08 | Direct |
57184,49899,57196 57184 - Growth factor receptor domain 49899 - Concanavalin A-like lectins/glucanases 57196 - EGF/Laminin | 9.568e-07 | Direct |
57196,57184,49899 57196 - EGF/Laminin 57184 - Growth factor receptor domain 49899 - Concanavalin A-like lectins/glucanases | 1.937e-06 | Direct |
57603,82895,82895 57603 - FnI-like domain 82895 - TSP-1 type 1 repeat 82895 - TSP-1 type 1 repeat | 7.79e-06 | Direct |
82895,82895,57196 82895 - TSP-1 type 1 repeat 82895 - TSP-1 type 1 repeat 57196 - EGF/Laminin | 7.79e-06 | Direct |
101288,50156,50044 101288 - L27 domain 50156 - PDZ domain-like 50044 - SH3-domain | 0.0005411 | Direct |
57196,57196,57184 57196 - EGF/Laminin 57196 - EGF/Laminin 57184 - Growth factor receptor domain | 0.006738 | Inherited |
57667,57667,57667 57667 - beta-beta-alpha zinc fingers 57667 - beta-beta-alpha zinc fingers 57667 - beta-beta-alpha zinc fingers | 1 | Inherited |
48065,50729,50044 48065 - DBL homology domain (DH-domain) 50729 - PH domain-like 50044 - SH3-domain | 0.005592 | Inherited |
57716,57716,57716 57716 - Glucocorticoid receptor-like (DNA-binding domain) 57716 - Glucocorticoid receptor-like (DNA-binding domain) 57716 - Glucocorticoid receptor-like (DNA-binding domain) | 0.1226 | Inherited |
47090,55486,50923 47090 - PGBD-like 55486 - Metalloproteases ("zincins"), catalytic domain 50923 - Hemopexin-like domain | 0.05309 | Inherited |
50156,50044,52540 50156 - PDZ domain-like 50044 - SH3-domain 52540 - P-loop containing nucleoside triphosphate hydrolases | 0.09167 | Inherited |
82895,82895,82895 82895 - TSP-1 type 1 repeat 82895 - TSP-1 type 1 repeat 82895 - TSP-1 type 1 repeat | 0.003031 | Inherited |
57196,57424,57424 57196 - EGF/Laminin 57424 - LDL receptor-like module 57424 - LDL receptor-like module | 0.001595 | Inherited |
63825,57196,57424 63825 - YWTD domain 57196 - EGF/Laminin 57424 - LDL receptor-like module | 0.001595 | Inherited |
57424,57424,57424 57424 - LDL receptor-like module 57424 - LDL receptor-like module 57424 - LDL receptor-like module | 0.3384 | Inherited |
49265,49265,56496 49265 - Fibronectin type III 49265 - Fibronectin type III 56496 - Fibrinogen C-terminal domain-like | 0.001929 | Inherited |
49265,49265,49265 49265 - Fibronectin type III 49265 - Fibronectin type III 49265 - Fibronectin type III | 0.3244 | Inherited |
Plot distribution on phylogenetic tree for Individual Supra-domains annotated by this GO term
 |
Plot tree as:
| |
Download Newick format tree:
| |
Browsing in Tree_gateway:
|
(show help)
Trees by TreeVector
A presence/absence matrix is generated using protein domains and supradomains
for all genomes in SUPERFAMILY. The RAxML
software is used to produce a single, large tree topology using
heuristic parsimony methods. Genome combinations, or specific clades, can be displayed as
if individual trees had been produced. However, this data is extracted from the single
large tree. This produces a higher quality topology than if the trees had been produced
on their own, and allows the trees to be displayed instantly.
|