SUPERFAMILY 1.75 HMM library and genome assignments server

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Biological Process (BP): cellular macromolecule localization

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Jump to [ Top · GO Hierarchy · Superfamily · Family · Supra-domain ]

Root: GO Hierarchy Containing Three Sub-Ontologies (BP, MF, CC)

Shortest distance to current term (+ for parents, - for children) GO term [GO ID] <#Children> #High-quality
(SF|FA)
#Supra-domain
(Single|Duplex|Triple)
+ + + 3:   biological_process [GO:0008150] <24>
+ + 2:   localization [GO:0051179] <10>(91|101) (503|489|298)
+ 1:   cellular localization [GO:0051641] <12>(36|37) (304|235|116)
+ 1:   macromolecule localization [GO:0033036] <6>(43|46) (298|213|137)
0:   cellular macromolecule localization [GO:0070727] <4>(19|20) (203|136|73)
- 1:   cellular protein localization [GO:0034613] <24>(19|20) (195|134|72)
- 1:   intracellular mRNA localization [GO:0008298] <3>(0|0) (11|4|1)
- 1:   callose deposition in cell wall [GO:0052543] <1>(0|0) (2|0|0)
- 1:   establishment of macromolecular complex localization to telomere [GO:0097695](0|0) (0|0|0)


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Superfamily

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SCOP termFDR (singleton)FDR (all)Annotation (direct or inherited)
ARM repeat0.000008320.000001087Direct
Chaperone J-domain0.00067830.00002655Direct
Metallothionein0.0000018360.00005526Direct
Preprotein translocase SecE subunit0.00052280.000779Direct
Roadblock/LC7 domain00.00000000006599Direct
Signal recognition particle alu RNA binding heterodimer, SRP9/140.0000000013730.0000000004926Direct
Tim10-like0.00000000033110.0000000001453Direct
EF-hand0.08881Inherited
LexA/Signal peptidase0.12610.2482Inherited
Clavaminate synthase-like0.15661Inherited
Immunoglobulin0.47691Inherited
P-loop containing nucleoside triphosphate hydrolases0.0000035761Inherited
4-helical cytokines11Inherited
NAD(P)-linked oxidoreductase0.16530.7704Inherited
Histone-fold0.53650.6879Inherited
Profilin (actin-binding protein)0.011970.01642Inherited
Preprotein translocase SecY subunit0.00064110.00103Inherited
NTF2-like0.013560.000003179Inherited
WD40 repeat-like0.0077710.0004949Inherited


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Family

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SCOP termFDR (singleton)FDR (all)Annotation (direct or inherited)
AlkB-like0.00000053370.0001656Direct
Armadillo repeat00Direct
Cell cycle arrest protein BUB30.0000083550.00008462Direct
Metallothionein0.0000052740.0000875Direct
Preprotein translocase SecE subunit0.00049760.0006891Direct
Preprotein translocase SecY subunit0.00064030.0009262Direct
Roadblock/LC7 domain00.0000000006381Direct
Signal recognition particle alu RNA binding heterodimer, SRP9/140.0000000025180.0000000006872Direct
Tim10/DDP0.00000000035460.0000000001337Direct
Calmodulin-like0.030530.03565Inherited
Tetratricopeptide repeat (TPR)0.0050250.00000000679Inherited
G proteins0.0000052180.007277Inherited
Extended AAA-ATPase domain0.0052760.3163Inherited
Cold shock DNA-binding domain-like0.15450.8301Inherited
Aldo-keto reductases (NADP)0.2450.8046Inherited
Nucleosome core histones0.36430.1612Inherited
Profilin (actin-binding protein)0.011310.01479Inherited
Interferons/interleukin-10 (IL-10)0.00170.01749Inherited
NTF2-like0.013120.00009345Inherited
WD40-repeat0.049320.0003812Inherited


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Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Cystine-knot cytokines0Direct
FLJ32549 domain-like0Direct
Nucleoporin domain0Direct
C-terminal autoproteolytic domain of nucleoporin nup980Direct
FLJ32549 C-terminal domain-like0Direct
MoeA C-terminal domain-like0.00000000000004381Direct
MoeA N-terminal region -like0.00000000000006739Direct
Roadblock/LC7 domain0.00000000003776Direct
Molybdenum cofactor biosynthesis proteins0.00000000007357Direct
Tim10-like0.00000000008347Direct
TPR-like0.00000000009794Direct
HR1 repeat0.0000000001876Direct
Mitochondrial import receptor subunit Tom200.0000000002863Direct
Signal recognition particle alu RNA binding heterodimer, SRP9/140.0000000002863Direct
SRP190.0000000003971Direct
WW domain0.000000002811Direct
Heat shock protein 70kD (HSP70), peptide-binding domain0.0000001268Direct
G protein-binding domain0.000000181Direct
DPP6 N-terminal domain-like0.0000002269Direct
Heat shock protein 70kD (HSP70), C-terminal subdomain0.0000002541Direct
Ubiquitin-like0.0000004663Direct
ARM repeat0.000000696Direct
NTF2-like0.000002066Direct
Dystroglycan, domain 20.000002735Direct
A middle domain of Talin 10.000005018Direct
LuxS/MPP-like metallohydrolase0.000005697Direct
Second domain of FERM0.000007064Direct
alpha-catenin/vinculin-like0.00001139Direct
RILP dimerisation region0.00001139Direct
DnaJ/Hsp40 cysteine-rich domain0.00001345Direct
Chaperone J-domain0.0000178Direct
HSP40/DnaJ peptide-binding domain0.00003699Direct
Metallothionein0.00003738Direct
RNA-binding domain, RBD0.00004542Direct
Calpain large subunit, middle domain (domain III)0.0000687Direct
Tricorn protease domain 20.00007586Direct
Head domain of nucleotide exchange factor GrpE0.0001748Direct
Coiled-coil domain of nucleotide exchange factor GrpE0.0002162Direct
Ran binding protein zinc finger-like0.0002508Direct
RL5-like0.0002644Direct
WD40 repeat-like0.0003477Direct
Rhomboid-like0.0004646Direct
Prion-like0.0005455Direct
Preprotein translocase SecE subunit0.0005515Direct
Preprotein translocase SecY subunit0.0007332Direct
SNARE fusion complex1Inherited
Phospholipase D/nuclease0.1943Inherited
HSP20-like chaperones0.3665Inherited
RCC1/BLIP-II0.07361Inherited
HCP-like0.2036Inherited
SAM/Pointed domain1Inherited
Ankyrin repeat0.9607Inherited
alpha/beta-Hydrolases1Inherited
Concanavalin A-like lectins/glucanases0.6554Inherited
Polo-box domain0.01237Inherited
MIT domain0.1302Inherited
PA domain0.7398Inherited
GAT-like domain0.0397Inherited
C2 domain (Calcium/lipid-binding domain, CaLB)1Inherited
t-snare proteins1Inherited
RING/U-box0.5351Inherited
UBC-like1Inherited
Cdc48 domain 2-like0.7529Inherited
ADC-like0.8398Inherited
AN1-like Zinc finger0.008843Inherited
Tetraspanin0.6081Inherited
TNF-like0.002712Inherited
Moesin tail domain0.4286Inherited
Voltage-gated potassium channels0.6964Inherited
DNase I-like0.8673Inherited
L27 domain0.8952Inherited
Protein prenylyltransferase0.05471Inherited
P-loop containing nucleoside triphosphate hydrolases1Inherited
beta-beta-alpha zinc fingers1Inherited
Mannose 6-phosphate receptor domain0.2042Inherited
Actin-like ATPase domain0.2811Inherited
Hect, E3 ligase catalytic domain0.104Inherited
Formin homology 2 domain (FH2 domain)0.3705Inherited
CCCH zinc finger0.2839Inherited
Growth factor receptor domain0.3388Inherited
Fibronectin type III1Inherited
Translation proteins SH3-like domain0.4339Inherited
Signal peptide-binding domain0.002572Inherited
Domain of the SRP/SRP receptor G-proteins0.001193Inherited
Sec63 N-terminal domain-like0.04614Inherited
PapD-like0.412Inherited
Bcl-2 inhibitors of programmed cell death1Inherited
FtsH protease domain-like0.4472Inherited
Cysteine alpha-hairpin motif0.05471Inherited
Mitochondrial carrier1Inherited
Homeodomain-like1Inherited
EF-hand1Inherited
Tubby C-terminal domain-like0.005838Inherited
Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit0.03471Inherited
PX domain0.1124Inherited
Notch domain0.1609Inherited
Cytochrome P4501Inherited
HLH, helix-loop-helix DNA-binding domain1Inherited
F-box domain1Inherited
(Phosphotyrosine protein) phosphatases II1Inherited
Prokaryotic lipoproteins and lipoprotein localization factors0.02551Inherited
ENTH/VHS domain0.01647Inherited
PDZ domain-like0.8972Inherited
SEA domain0.002608Inherited
Kringle-like0.4429Inherited
LDL receptor-like module0.5637Inherited
Immunoglobulin1Inherited
EGF/Laminin0.2522Inherited
YWTD domain0.1426Inherited
Kazal-type serine protease inhibitors0.8053Inherited
Frizzled cysteine-rich domain0.9534Inherited
TIMP-like0.4038Inherited
Integrin domains0.5249Inherited
Nicotinic receptor ligand binding domain-like0.8144Inherited
Neurotransmitter-gated ion-channel transmembrane pore0.9177Inherited
GAS2 domain-like0.1609Inherited
Spectrin repeat1Inherited
CRAL/TRIO N-terminal domain0.5867Inherited
CRAL/TRIO domain0.8053Inherited
Actin depolymerizing proteins0.001587Inherited
Class I glutamine amidotransferase-like0.9988Inherited
DBL homology domain (DH-domain)0.4762Inherited
BAR/IMD domain-like0.03716Inherited
ArfGap/RecO-like zinc finger0.04611Inherited
POZ domain0.328Inherited
Kelch motif0.5489Inherited
EB1 dimerisation domain-like0.03087Inherited
Intermediate filament protein, coiled coil region0.3648Inherited
VPS28 C-terminal domain-like0.04614Inherited
GLA-domain0.09417Inherited
Profilin (actin-binding protein)0.01237Inherited
IP3 receptor type 1 binding core, domain 21Inherited
MIR domain1Inherited
STAT0.6307Inherited
Cryptochrome/photolyase FAD-binding domain0.005525Inherited
Cryptochrome/photolyase, N-terminal domain0.01188Inherited
Transcription factor STAT-4 N-domain0.5249Inherited
Lamin A/C globular tail domain0.002572Inherited
Orange domain-like0.006647Inherited
DNA-binding domain0.3538Inherited
4-helical cytokines1Inherited
SIS domain0.2344Inherited
NAD(P)-linked oxidoreductase0.6753Inherited
SH2 domain1Inherited
Toll/Interleukin receptor TIR domain1Inherited
BRCT domain0.006677Inherited
Nucleic acid-binding proteins0.179Inherited
Histone-fold0.5976Inherited
"Winged helix" DNA-binding domain0.7597Inherited
ADP-ribosylation0.1829Inherited
Chromo domain-like0.3356Inherited
Zn-finger domain of Sec23/240.797Inherited
C-terminal, gelsolin-like domain of Sec23/240.9074Inherited
Helical domain of Sec23/240.9247Inherited
beta-sandwich domain of Sec23/240.9739Inherited
vWA-like1Inherited
Calponin-homology domain, CH-domain0.3583Inherited
DUSP-like0.001151Inherited
E set domains1Inherited
Cysteine proteinases0.8977Inherited
Domain of poly(ADP-ribose) polymerase0.01182Inherited
WGR domain-like0.01404Inherited
Quinoprotein alcohol dehydrogenase-like0.9318Inherited
Cysteine-rich domain1Inherited
PH domain-like0.04997Inherited
Protein kinase-like (PK-like)0.01391Inherited
KA1-like0.5249Inherited
Ribonuclease H-like1Inherited
SH3-domain0.06021Inherited
Tudor/PWWP/MBT0.006173Inherited
Eukaryotic type KH-domain (KH-domain type I)0.6081Inherited
Tropomyosin0.8887Inherited
SMAD/FHA domain0.9126Inherited
Family A G protein-coupled receptor-like1Inherited
Glucocorticoid receptor-like (DNA-binding domain)0.7935Inherited
FAT domain of focal adhesion kinase0.002572Inherited
I/LWEQ domain0.01917Inherited
Cadherin-like0.05054Inherited
Invasin/intimin cell-adhesion fragments0.005836Inherited
Clathrin adaptor appendage domain0.05644Inherited
FKBP-like0.7895Inherited
GST C-terminal domain-like0.9771Inherited
Fzo-like conserved region0.2988Inherited
LexA/Signal peptidase0.2036Inherited
GroEL-intermediate domain like0.332Inherited
GroEL apical domain-like0.4603Inherited
GroEL equatorial domain-like0.6607Inherited
GAF domain-like0.002022Inherited
HD-domain/PDEase-like0.326Inherited
Sialidases0.01188Inherited
Sec1/munc18-like (SM) proteins0.998Inherited
Oligoxyloglucan reducing end-specific cellobiohydrolase0.003178Inherited
Endosomal sorting complex assembly domain0.4603Inherited
SNARE-like0.6605Inherited
FAD-linked reductases, C-terminal domain1Inherited
p53-like transcription factors0.838Inherited
SAP domain0.2313Inherited
Clavaminate synthase-like1Inherited
DEATH domain0.05374Inherited
UBA-like0.1737Inherited
L domain-like0.6132Inherited
Fibrinogen C-terminal domain-like0.02761Inherited
Galactose-binding domain-like0.6195Inherited

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
103652,50729
  • 103652 - G protein-binding domain
  • 50729 - PH domain-like
  • 0Direct
    50156,64268
  • 50156 - PDZ domain-like
  • 64268 - PX domain
  • 0Direct
    158548,160651
  • 158548 - FLJ32549 domain-like
  • 160651 - FLJ32549 C-terminal domain-like
  • 0Direct
    53218,63867
  • 53218 - Molybdenum cofactor biosynthesis proteins
  • 63867 - MoeA C-terminal domain-like
  • 0.00000000000004381Direct
    51045,50156
  • 51045 - WW domain
  • 50156 - PDZ domain-like
  • 0.0000000000000573Direct
    63882,53218
  • 63882 - MoeA N-terminal region -like
  • 53218 - Molybdenum cofactor biosynthesis proteins
  • 0.00000000000006739Direct
    64268,54236
  • 64268 - PX domain
  • 54236 - Ubiquitin-like
  • 0.0000000000002269Direct
    52540,51045
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 51045 - WW domain
  • 0.0000000002776Direct
    50729,90209
  • 50729 - PH domain-like
  • 90209 - Ran binding protein zinc finger-like
  • 0.0000000003971Direct
    51045,51045
  • 51045 - WW domain
  • 51045 - WW domain
  • 0.000000001997Direct
    57196,56496
  • 57196 - EGF/Laminin
  • 56496 - Fibrinogen C-terminal domain-like
  • 0.000000002284Direct
    56496,49899
  • 56496 - Fibrinogen C-terminal domain-like
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.000000002284Direct
    56112,82615
  • 56112 - Protein kinase-like (PK-like)
  • 82615 - Polo-box domain
  • 0.00000000309Direct
    50729,74788
  • 50729 - PH domain-like
  • 74788 - Cullin repeat-like
  • 0.00000002554Direct
    47031,50729
  • 47031 - Second domain of FERM
  • 50729 - PH domain-like
  • 0.00000007733Direct
    109885,47220
  • 109885 - I/LWEQ domain
  • 47220 - alpha-catenin/vinculin-like
  • 0.0000000863Direct
    100920,100934
  • 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
  • 100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain
  • 0.00000009642Direct
    53067,100920
  • 53067 - Actin-like ATPase domain
  • 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
  • 0.0000001268Direct
    46565,57938
  • 46565 - Chaperone J-domain
  • 57938 - DnaJ/Hsp40 cysteine-rich domain
  • 0.000000197Direct
    64593,74853
  • 64593 - Intermediate filament protein, coiled coil region
  • 74853 - Lamin A/C globular tail domain
  • 0.0000002338Direct
    53697,53697
  • 53697 - SIS domain
  • 53697 - SIS domain
  • 0.0000006344Direct
    50729,57889
  • 50729 - PH domain-like
  • 57889 - Cysteine-rich domain
  • 0.0000006774Direct
    49758,47473
  • 49758 - Calpain large subunit, middle domain (domain III)
  • 47473 - EF-hand
  • 0.00000206Direct
    55781,109604
  • 55781 - GAF domain-like
  • 109604 - HD-domain/PDEase-like
  • 0.000002196Direct
    49313,111006
  • 49313 - Cadherin-like
  • 111006 - Dystroglycan, domain 2
  • 0.000002735Direct
    50978,48452
  • 50978 - WD40 repeat-like
  • 48452 - TPR-like
  • 0.000002735Direct
    50242,100895
  • 50242 - TIMP-like
  • 100895 - Kazal-type serine protease inhibitors
  • 0.000002839Direct
    56112,50978
  • 56112 - Protein kinase-like (PK-like)
  • 50978 - WD40 repeat-like
  • 0.00000476Direct
    109880,109885
  • 109880 - A middle domain of Talin 1
  • 109885 - I/LWEQ domain
  • 0.000005018Direct
    57938,49493
  • 57938 - DnaJ/Hsp40 cysteine-rich domain
  • 49493 - HSP40/DnaJ peptide-binding domain
  • 0.000005374Direct
    82171,53474
  • 82171 - DPP6 N-terminal domain-like
  • 53474 - alpha/beta-Hydrolases
  • 0.000008271Direct
    63411,63411
  • 63411 - LuxS/MPP-like metallohydrolase
  • 63411 - LuxS/MPP-like metallohydrolase
  • 0.000008974Direct
    109885,109885
  • 109885 - I/LWEQ domain
  • 109885 - I/LWEQ domain
  • 0.0000093Direct
    47220,47220
  • 47220 - alpha-catenin/vinculin-like
  • 47220 - alpha-catenin/vinculin-like
  • 0.00001139Direct
    50156,103657
  • 50156 - PDZ domain-like
  • 103657 - BAR/IMD domain-like
  • 0.00001204Direct
    48452,48452
  • 48452 - TPR-like
  • 48452 - TPR-like
  • 0.0000151Direct
    50978,69322
  • 50978 - WD40 repeat-like
  • 69322 - Tricorn protease domain 2
  • 0.00001709Direct
    57196,100895
  • 57196 - EGF/Laminin
  • 100895 - Kazal-type serine protease inhibitors
  • 0.00001793Direct
    46565,158702
  • 46565 - Chaperone J-domain
  • 158702 - Sec63 N-terminal domain-like
  • 0.00001793Direct
    51045,56204
  • 51045 - WW domain
  • 56204 - Hect, E3 ligase catalytic domain
  • 0.00002485Direct
    64268,50044
  • 64268 - PX domain
  • 50044 - SH3-domain
  • 0.00002636Direct
    54236,47031
  • 54236 - Ubiquitin-like
  • 47031 - Second domain of FERM
  • 0.00005674Direct
    50729,57863
  • 50729 - PH domain-like
  • 57863 - ArfGap/RecO-like zinc finger
  • 0.0000894Direct
    49493,49493
  • 49493 - HSP40/DnaJ peptide-binding domain
  • 49493 - HSP40/DnaJ peptide-binding domain
  • 0.00009046Direct
    58014,51064
  • 58014 - Coiled-coil domain of nucleotide exchange factor GrpE
  • 51064 - Head domain of nucleotide exchange factor GrpE
  • 0.0001748Direct
    55781,55781
  • 55781 - GAF domain-like
  • 55781 - GAF domain-like
  • 0.0002549Direct
    100895,100895
  • 100895 - Kazal-type serine protease inhibitors
  • 100895 - Kazal-type serine protease inhibitors
  • 0.0007528Direct
    50249,50249
  • 50249 - Nucleic acid-binding proteins
  • 50249 - Nucleic acid-binding proteins
  • 0.0007903Direct
    52058,54427
  • 52058 - L domain-like
  • 54427 - NTF2-like
  • 0.0007903Direct
    101288,50156
  • 101288 - L27 domain
  • 50156 - PDZ domain-like
  • 0.8716Inherited
    50044,50156
  • 50044 - SH3-domain
  • 50156 - PDZ domain-like
  • 0.01188Inherited
    50156,50156
  • 50156 - PDZ domain-like
  • 50156 - PDZ domain-like
  • 0.02874Inherited
    49899,49899
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.0711Inherited
    82615,82615
  • 82615 - Polo-box domain
  • 82615 - Polo-box domain
  • 0.002572Inherited
    50044,52540
  • 50044 - SH3-domain
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.043Inherited
    50156,50044
  • 50156 - PDZ domain-like
  • 50044 - SH3-domain
  • 0.001868Inherited
    56112,48371
  • 56112 - Protein kinase-like (PK-like)
  • 48371 - ARM repeat
  • 0.1609Inherited
    52540,52540
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.623Inherited
    50692,54585
  • 50692 - ADC-like
  • 54585 - Cdc48 domain 2-like
  • 0.8398Inherited
    57184,49899
  • 57184 - Growth factor receptor domain
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.02538Inherited
    57630,57196
  • 57630 - GLA-domain
  • 57196 - EGF/Laminin
  • 0.5867Inherited
    48403,48403
  • 48403 - Ankyrin repeat
  • 48403 - Ankyrin repeat
  • 0.2036Inherited
    53067,53067
  • 53067 - Actin-like ATPase domain
  • 53067 - Actin-like ATPase domain
  • 0.1087Inherited
    57196,49899
  • 57196 - EGF/Laminin
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.05695Inherited
    52540,47446
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 47446 - Signal peptide-binding domain
  • 0.002572Inherited
    47364,52540
  • 47364 - Domain of the SRP/SRP receptor G-proteins
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.001193Inherited
    52540,140990
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 140990 - FtsH protease domain-like
  • 0.4472Inherited
    50729,56112
  • 50729 - PH domain-like
  • 56112 - Protein kinase-like (PK-like)
  • 0.005525Inherited
    50978,50978
  • 50978 - WD40 repeat-like
  • 50978 - WD40 repeat-like
  • 0.001559Inherited
    46785,46785
  • 46785 - "Winged helix" DNA-binding domain
  • 46785 - "Winged helix" DNA-binding domain
  • 0.02538Inherited
    50156,52540
  • 50156 - PDZ domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.001647Inherited
    57196,63825
  • 57196 - EGF/Laminin
  • 63825 - YWTD domain
  • 0.2006Inherited
    63825,57196
  • 63825 - YWTD domain
  • 57196 - EGF/Laminin
  • 0.2946Inherited
    57424,57184
  • 57424 - LDL receptor-like module
  • 57184 - Growth factor receptor domain
  • 0.6307Inherited
    48726,48726
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 0.9453Inherited
    49899,57196
  • 49899 - Concanavalin A-like lectins/glucanases
  • 57196 - EGF/Laminin
  • 0.02789Inherited
    57424,57424
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 0.527Inherited
    57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.8918Inherited
    63712,90112
  • 63712 - Nicotinic receptor ligand binding domain-like
  • 90112 - Neurotransmitter-gated ion-channel transmembrane pore
  • 0.9082Inherited
    47473,143575
  • 47473 - EF-hand
  • 143575 - GAS2 domain-like
  • 0.1609Inherited
    46966,46966
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 0.5301Inherited
    55753,55753
  • 55753 - Actin depolymerizing proteins
  • 55753 - Actin depolymerizing proteins
  • 0.01237Inherited
    48452,81901
  • 48452 - TPR-like
  • 81901 - HCP-like
  • 0.02551Inherited
    48065,50729
  • 48065 - DBL homology domain (DH-domain)
  • 50729 - PH domain-like
  • 0.3002Inherited
    57863,48403
  • 57863 - ArfGap/RecO-like zinc finger
  • 48403 - Ankyrin repeat
  • 0.01237Inherited
    47576,140612
  • 47576 - Calponin-homology domain, CH-domain
  • 140612 - EB1 dimerisation domain-like
  • 0.01452Inherited
    116846,52540
  • 116846 - MIT domain
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.06185Inherited
    48464,57903
  • 48464 - ENTH/VHS domain
  • 57903 - FYVE/PHD zinc finger
  • 0.08704Inherited
    57630,57184
  • 57630 - GLA-domain
  • 57184 - Growth factor receptor domain
  • 0.002572Inherited
    103657,50729
  • 103657 - BAR/IMD domain-like
  • 50729 - PH domain-like
  • 0.04364Inherited
    82109,82109
  • 82109 - MIR domain
  • 82109 - MIR domain
  • 1Inherited
    47576,57716
  • 47576 - Calponin-homology domain, CH-domain
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 0.02551Inherited
    52058,52540
  • 52058 - L domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.001138Inherited
    63748,63748
  • 63748 - Tudor/PWWP/MBT
  • 63748 - Tudor/PWWP/MBT
  • 0.003178Inherited
    52799,49562
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 0.006284Inherited
    64268,103657
  • 64268 - PX domain
  • 103657 - BAR/IMD domain-like
  • 0.684Inherited
    47661,58038
  • 47661 - t-snare proteins
  • 58038 - SNARE fusion complex
  • 0.771Inherited
    49417,55550
  • 49417 - p53-like transcription factors
  • 55550 - SH2 domain
  • 0.6307Inherited
    47655,49417
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 0.6307Inherited
    52425,48173
  • 52425 - Cryptochrome/photolyase, N-terminal domain
  • 48173 - Cryptochrome/photolyase FAD-binding domain
  • 0.01188Inherited
    48092,47655
  • 48092 - Transcription factor STAT-4 N-domain
  • 47655 - STAT
  • 0.5249Inherited
    50729,55550
  • 50729 - PH domain-like
  • 55550 - SH2 domain
  • 0.01922Inherited
    57184,63825
  • 57184 - Growth factor receptor domain
  • 63825 - YWTD domain
  • 0.1444Inherited
    56112,56112
  • 56112 - Protein kinase-like (PK-like)
  • 56112 - Protein kinase-like (PK-like)
  • 0.02378Inherited
    47459,158457
  • 47459 - HLH, helix-loop-helix DNA-binding domain
  • 158457 - Orange domain-like
  • 0.006232Inherited
    63825,57184
  • 63825 - YWTD domain
  • 57184 - Growth factor receptor domain
  • 0.08704Inherited
    57184,57184
  • 57184 - Growth factor receptor domain
  • 57184 - Growth factor receptor domain
  • 0.771Inherited
    55550,56112
  • 55550 - SH2 domain
  • 56112 - Protein kinase-like (PK-like)
  • 0.7249Inherited
    50249,46785
  • 50249 - Nucleic acid-binding proteins
  • 46785 - "Winged helix" DNA-binding domain
  • 0.002572Inherited
    82919,53300
  • 82919 - Zn-finger domain of Sec23/24
  • 53300 - vWA-like
  • 0.797Inherited
    81811,82754
  • 81811 - Helical domain of Sec23/24
  • 82754 - C-terminal, gelsolin-like domain of Sec23/24
  • 0.9247Inherited
    81296,81296
  • 81296 - E set domains
  • 81296 - E set domains
  • 0.07218Inherited
    53300,81995
  • 53300 - vWA-like
  • 81995 - beta-sandwich domain of Sec23/24
  • 0.527Inherited
    81995,81811
  • 81995 - beta-sandwich domain of Sec23/24
  • 81811 - Helical domain of Sec23/24
  • 0.6333Inherited
    142921,47587
  • 142921 - WGR domain-like
  • 47587 - Domain of poly(ADP-ribose) polymerase
  • 0.005836Inherited
    47587,56399
  • 47587 - Domain of poly(ADP-ribose) polymerase
  • 56399 - ADP-ribosylation
  • 0.01079Inherited
    52113,52113
  • 52113 - BRCT domain
  • 52113 - BRCT domain
  • 0.01237Inherited
    57889,48350
  • 57889 - Cysteine-rich domain
  • 48350 - GTPase activation domain, GAP
  • 0.05471Inherited
    81383,50978
  • 81383 - F-box domain
  • 50978 - WD40 repeat-like
  • 0.1694Inherited
    54928,54928
  • 54928 - RNA-binding domain, RBD
  • 54928 - RNA-binding domain, RBD
  • 0.01215Inherited
    54791,54791
  • 54791 - Eukaryotic type KH-domain (KH-domain type I)
  • 54791 - Eukaryotic type KH-domain (KH-domain type I)
  • 0.7249Inherited
    57184,57196
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 0.2658Inherited
    57196,57184
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 0.4429Inherited
    57716,57716
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 0.07142Inherited
    90209,90209
  • 90209 - Ran binding protein zinc finger-like
  • 90209 - Ran binding protein zinc finger-like
  • 0.005198Inherited
    52833,47616
  • 52833 - Thioredoxin-like
  • 47616 - GST C-terminal domain-like
  • 1Inherited
    54849,52029
  • 54849 - GroEL-intermediate domain like
  • 52029 - GroEL apical domain-like
  • 0.3248Inherited
    48592,54849
  • 48592 - GroEL equatorial domain-like
  • 54849 - GroEL-intermediate domain like
  • 0.4914Inherited
    54534,48452
  • 54534 - FKBP-like
  • 48452 - TPR-like
  • 0.05471Inherited
    140111,140427
  • 140111 - Endosomal sorting complex assembly domain
  • 140427 - VPS28 C-terminal domain-like
  • 0.08704Inherited
    50044,50044
  • 50044 - SH3-domain
  • 50044 - SH3-domain
  • 0.8053Inherited
    51905,54373
  • 51905 - FAD/NAD(P)-binding domain
  • 54373 - FAD-linked reductases, C-terminal domain
  • 0.9655Inherited
    54928,52058
  • 54928 - RNA-binding domain, RBD
  • 52058 - L domain-like
  • 0.003178Inherited
    54427,46934
  • 54427 - NTF2-like
  • 46934 - UBA-like
  • 0.001589Inherited
    48371,48371
  • 48371 - ARM repeat
  • 48371 - ARM repeat
  • 0.002257Inherited
    49785,49899
  • 49785 - Galactose-binding domain-like
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.001193Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    57630,57196,57184
  • 57630 - GLA-domain
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 0Direct
    103652,50729,57889
  • 103652 - G protein-binding domain
  • 50729 - PH domain-like
  • 57889 - Cysteine-rich domain
  • 0Direct
    50156,64268,54236
  • 50156 - PDZ domain-like
  • 64268 - PX domain
  • 54236 - Ubiquitin-like
  • 0Direct
    57196,57196,100895
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 100895 - Kazal-type serine protease inhibitors
  • 0Direct
    51045,51045,50156
  • 51045 - WW domain
  • 51045 - WW domain
  • 50156 - PDZ domain-like
  • 0.00000000000002322Direct
    63882,53218,63867
  • 63882 - MoeA N-terminal region -like
  • 53218 - Molybdenum cofactor biosynthesis proteins
  • 63867 - MoeA C-terminal domain-like
  • 0.00000000000004381Direct
    55781,55781,55781
  • 55781 - GAF domain-like
  • 55781 - GAF domain-like
  • 55781 - GAF domain-like
  • 0.000000000007457Direct
    52540,51045,51045
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 51045 - WW domain
  • 51045 - WW domain
  • 0.0000000001112Direct
    49899,57196,56496
  • 49899 - Concanavalin A-like lectins/glucanases
  • 57196 - EGF/Laminin
  • 56496 - Fibrinogen C-terminal domain-like
  • 0.000000002284Direct
    56496,49899,49899
  • 56496 - Fibrinogen C-terminal domain-like
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.000000002284Direct
    57196,56496,49899
  • 57196 - EGF/Laminin
  • 56496 - Fibrinogen C-terminal domain-like
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.000000002284Direct
    56112,82615,82615
  • 56112 - Protein kinase-like (PK-like)
  • 82615 - Polo-box domain
  • 82615 - Polo-box domain
  • 0.00000000309Direct
    57184,57184,63825
  • 57184 - Growth factor receptor domain
  • 57184 - Growth factor receptor domain
  • 63825 - YWTD domain
  • 0.0000000161Direct
    63825,57184,57184
  • 63825 - YWTD domain
  • 57184 - Growth factor receptor domain
  • 57184 - Growth factor receptor domain
  • 0.0000000161Direct
    50978,50978,48452
  • 50978 - WD40 repeat-like
  • 50978 - WD40 repeat-like
  • 48452 - TPR-like
  • 0.0000000161Direct
    109885,109885,47220
  • 109885 - I/LWEQ domain
  • 109885 - I/LWEQ domain
  • 47220 - alpha-catenin/vinculin-like
  • 0.0000000863Direct
    109885,47220,47220
  • 109885 - I/LWEQ domain
  • 47220 - alpha-catenin/vinculin-like
  • 47220 - alpha-catenin/vinculin-like
  • 0.0000000863Direct
    53067,100920,100934
  • 53067 - Actin-like ATPase domain
  • 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
  • 100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain
  • 0.00000009642Direct
    53067,53067,100920
  • 53067 - Actin-like ATPase domain
  • 53067 - Actin-like ATPase domain
  • 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
  • 0.0000002541Direct
    109885,109885,109885
  • 109885 - I/LWEQ domain
  • 109885 - I/LWEQ domain
  • 109885 - I/LWEQ domain
  • 0.0000002772Direct
    55781,55781,109604
  • 55781 - GAF domain-like
  • 55781 - GAF domain-like
  • 109604 - HD-domain/PDEase-like
  • 0.0000007727Direct
    46565,57938,49493
  • 46565 - Chaperone J-domain
  • 57938 - DnaJ/Hsp40 cysteine-rich domain
  • 49493 - HSP40/DnaJ peptide-binding domain
  • 0.00000145Direct
    57184,57196,49899
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.000002839Direct
    57630,57184,57196
  • 57630 - GLA-domain
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 0.000002839Direct
    50242,100895,100895
  • 50242 - TIMP-like
  • 100895 - Kazal-type serine protease inhibitors
  • 100895 - Kazal-type serine protease inhibitors
  • 0.000002839Direct
    64268,50044,50044
  • 64268 - PX domain
  • 50044 - SH3-domain
  • 50044 - SH3-domain
  • 0.000003572Direct
    57938,49493,49493
  • 57938 - DnaJ/Hsp40 cysteine-rich domain
  • 49493 - HSP40/DnaJ peptide-binding domain
  • 49493 - HSP40/DnaJ peptide-binding domain
  • 0.000004622Direct
    109880,109885,109885
  • 109880 - A middle domain of Talin 1
  • 109885 - I/LWEQ domain
  • 109885 - I/LWEQ domain
  • 0.000005018Direct
    48452,48452,48452
  • 48452 - TPR-like
  • 48452 - TPR-like
  • 48452 - TPR-like
  • 0.000006913Direct
    50729,57863,48403
  • 50729 - PH domain-like
  • 57863 - ArfGap/RecO-like zinc finger
  • 48403 - Ankyrin repeat
  • 0.00002073Direct
    51045,51045,56204
  • 51045 - WW domain
  • 51045 - WW domain
  • 56204 - Hect, E3 ligase catalytic domain
  • 0.00002485Direct
    47364,52540,47446
  • 47364 - Domain of the SRP/SRP receptor G-proteins
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 47446 - Signal peptide-binding domain
  • 0.00003217Direct
    54236,47031,50729
  • 54236 - Ubiquitin-like
  • 47031 - Second domain of FERM
  • 50729 - PH domain-like
  • 0.00003896Direct
    103657,50729,57863
  • 103657 - BAR/IMD domain-like
  • 50729 - PH domain-like
  • 57863 - ArfGap/RecO-like zinc finger
  • 0.00009033Direct
    90209,90209,90209
  • 90209 - Ran binding protein zinc finger-like
  • 90209 - Ran binding protein zinc finger-like
  • 90209 - Ran binding protein zinc finger-like
  • 0.0001876Direct
    55550,56112,56112
  • 55550 - SH2 domain
  • 56112 - Protein kinase-like (PK-like)
  • 56112 - Protein kinase-like (PK-like)
  • 0.0002644Direct
    100895,100895,100895
  • 100895 - Kazal-type serine protease inhibitors
  • 100895 - Kazal-type serine protease inhibitors
  • 100895 - Kazal-type serine protease inhibitors
  • 0.0003169Direct
    50156,52540,51045
  • 50156 - PDZ domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 51045 - WW domain
  • 0.0003498Direct
    57586,57586,57586
  • 57586 - TNF receptor-like
  • 57586 - TNF receptor-like
  • 57586 - TNF receptor-like
  • 0.0003839Direct
    54928,52058,54427
  • 54928 - RNA-binding domain, RBD
  • 52058 - L domain-like
  • 54427 - NTF2-like
  • 0.0005515Direct
    48371,48371,48371
  • 48371 - ARM repeat
  • 48371 - ARM repeat
  • 48371 - ARM repeat
  • 0.0007332Direct
    49899,49899,49899
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.684Inherited
    50156,50044,52540
  • 50156 - PDZ domain-like
  • 50044 - SH3-domain
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.001868Inherited
    57196,57184,49899
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.02551Inherited
    57184,49899,49899
  • 57184 - Growth factor receptor domain
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.003178Inherited
    57196,49899,49899
  • 57196 - EGF/Laminin
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.01041Inherited
    48726,48726,48726
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 0.8192Inherited
    57196,63825,57196
  • 57196 - EGF/Laminin
  • 63825 - YWTD domain
  • 57196 - EGF/Laminin
  • 0.06185Inherited
    63825,57196,63825
  • 63825 - YWTD domain
  • 57196 - EGF/Laminin
  • 63825 - YWTD domain
  • 0.06185Inherited
    49899,57196,49899
  • 49899 - Concanavalin A-like lectins/glucanases
  • 57196 - EGF/Laminin
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.1076Inherited
    57424,57184,63825
  • 57424 - LDL receptor-like module
  • 57184 - Growth factor receptor domain
  • 63825 - YWTD domain
  • 0.6307Inherited
    57424,57424,57184
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 57184 - Growth factor receptor domain
  • 0.6307Inherited
    57424,57424,57424
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 0.527Inherited
    46966,46966,46966
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 0.5897Inherited
    57630,57184,49899
  • 57630 - GLA-domain
  • 57184 - Growth factor receptor domain
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.02551Inherited
    47576,57716,57716
  • 47576 - Calponin-homology domain, CH-domain
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 0.02551Inherited
    50729,55550,56112
  • 50729 - PH domain-like
  • 55550 - SH2 domain
  • 56112 - Protein kinase-like (PK-like)
  • 0.001952Inherited
    48092,47655,49417
  • 48092 - Transcription factor STAT-4 N-domain
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 0.5249Inherited
    47655,49417,55550
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 55550 - SH2 domain
  • 0.6307Inherited
    50249,50249,50249
  • 50249 - Nucleic acid-binding proteins
  • 50249 - Nucleic acid-binding proteins
  • 50249 - Nucleic acid-binding proteins
  • 0.002572Inherited
    81296,81296,81296
  • 81296 - E set domains
  • 81296 - E set domains
  • 81296 - E set domains
  • 0.02514Inherited
    82919,53300,81995
  • 82919 - Zn-finger domain of Sec23/24
  • 53300 - vWA-like
  • 81995 - beta-sandwich domain of Sec23/24
  • 0.3705Inherited
    81995,81811,82754
  • 81995 - beta-sandwich domain of Sec23/24
  • 81811 - Helical domain of Sec23/24
  • 82754 - C-terminal, gelsolin-like domain of Sec23/24
  • 0.6333Inherited
    53300,81995,81811
  • 53300 - vWA-like
  • 81995 - beta-sandwich domain of Sec23/24
  • 81811 - Helical domain of Sec23/24
  • 0.6333Inherited
    142921,47587,56399
  • 142921 - WGR domain-like
  • 47587 - Domain of poly(ADP-ribose) polymerase
  • 56399 - ADP-ribosylation
  • 0.005198Inherited
    54791,54791,54791
  • 54791 - Eukaryotic type KH-domain (KH-domain type I)
  • 54791 - Eukaryotic type KH-domain (KH-domain type I)
  • 54791 - Eukaryotic type KH-domain (KH-domain type I)
  • 0.05471Inherited
    47220,47220,47220
  • 47220 - alpha-catenin/vinculin-like
  • 47220 - alpha-catenin/vinculin-like
  • 47220 - alpha-catenin/vinculin-like
  • 0.002572Inherited
    57716,57716,57716
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 0.007236Inherited
    48592,54849,52029
  • 48592 - GroEL equatorial domain-like
  • 54849 - GroEL-intermediate domain like
  • 52029 - GroEL apical domain-like
  • 0.4834Inherited
    52058,54427,46934
  • 52058 - L domain-like
  • 54427 - NTF2-like
  • 46934 - UBA-like
  • 0.006284Inherited
    49785,49899,49899
  • 49785 - Galactose-binding domain-like
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.005525Inherited
    49899,49899,57196
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49899 - Concanavalin A-like lectins/glucanases
  • 57196 - EGF/Laminin
  • 0.08244Inherited
    50156,50156,50156
  • 50156 - PDZ domain-like
  • 50156 - PDZ domain-like
  • 50156 - PDZ domain-like
  • 0.5249Inherited


    Plot distribution on phylogenetic tree for Individual Supra-domains annotated by this GO term
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