SUPERFAMILY 1.75 HMM library and genome assignments server

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Cellular Component (CC): plasma membrane bounded cell projection

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Root: GO Hierarchy Containing Three Sub-Ontologies (BP, MF, CC)

Shortest distance to current term (+ for parents, - for children) GO term [GO ID] <#Children> #High-quality
(SF|FA)
#Supra-domain
(Single|Duplex|Triple)
+ + + 3:   cell [GO:0005623] <1>(276|347) (1031|1098|592)
+ + + 3:   cellular_component [GO:0005575] <22>
+ + 2:   cell part [GO:0044464] <113>(276|347) (1031|1098|592)
+ 1:   cell projection [GO:0042995] <7>(29|30) (214|222|131)
0:   plasma membrane bounded cell projection [GO:0120025] <24>(24|24) (207|221|131)
- 1:   plasma membrane bounded cell projection part [GO:0120038] <47>(15|14) (151|103|64)
- 1:   neuron projection [GO:0043005] <20>(10|11) (127|114|63)
- 1:   glial cell projection [GO:0097386] <5>(0|0) (3|1|0)
- 1:   mating projection [GO:0005937] <5>(0|0) (7|1|0)
- 1:   actin-based cell projection [GO:0098858] <4>(0|0) (38|30|23)
- 1:   rhabdomere [GO:0016028] <4>(0|0) (2|1|0)
- 1:   cilium [GO:0005929] <3>(10|9) (67|44|16)
- 1:   lamellipodium [GO:0030027] <3>(4|3) (27|33|26)
- 1:   macropinocytic cup [GO:0070685] <2>(0|0) (2|1|0)
- 1:   invadopodium [GO:0071437] <1>(0|0) (13|9|5)
- 1:   muscle cell projection [GO:0036194] <1>(0|0) (5|2|1)
- 1:   pollen tube [GO:0090406] <1>(0|0) (8|2|0)
- 1:   pseudopodium [GO:0031143] <1>(0|0) (1|3|1)
- 1:   root hair [GO:0035618] <1>(0|0) (0|0|0)
- 1:   ruffle [GO:0001726] <1>(2|1) (26|34|18)
- 1:   uropod [GO:0001931] <1>(0|0) (4|3|2)
- 1:   bleb [GO:0032059](0|0) (1|0|0)
- 1:   cell hair [GO:0070451](0|0) (0|0|0)
- 1:   cytoneme [GO:0035230](0|0) (3|0|0)
- 1:   dendritic cell dendrite [GO:0097511](0|0) (0|0|0)
- 1:   dinoflagellate peduncle [GO:1990905](0|0) (0|0|0)
- 1:   microspike [GO:0044393](0|0) (1|1|1)
- 1:   podocyte foot [GO:0098846](0|0) (0|0|0)
- 1:   podocyte primary projection [GO:0098854](0|0) (0|0|0)


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Superfamily

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SCOP termFDR (singleton)FDR (all)Annotation (direct or inherited)
Actin depolymerizing proteins0.00032420.000000000003517Direct
Annexin0.000000001750.000172Direct
Aquaporin-like0.000000046460.00004952Direct
Arp2/3 complex 16 kDa subunit ARPC50.00000024330.000007736Direct
BAR/IMD domain-like0.00060920Direct
Calponin-homology domain, CH-domain0.00026180Direct
Cu,Zn superoxide dismutase-like0.0000000001430.00002625Direct
Defensin-like0.00000000000021220.0000002582Direct
EF-hand00Direct
Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain0.0000082550.0000001915Direct
NAD kinase/diacylglycerol kinase-like0.0000013410.00000000009166Direct
Nucleoside diphosphate kinase, NDK0.00000041490.00000001835Direct
Regulator of G-protein signaling, RGS0.000024910.0000000000008605Direct
Spectrin repeat0.0000000014340Direct
Stathmin0.000000080070.00003402Direct
Transducin (heterotrimeric G protein), gamma chain0.000019680.00000000002476Direct
Protein kinase-like (PK-like)0.000000068210.008033Inherited
Immunoglobulin0.0054070.03346Inherited
MFS general substrate transporter0.48731Inherited
RNase A-like0.002750.06487Inherited
Lipocalins0.33040.7861Inherited
Family A G protein-coupled receptor-like0.014630.05978Inherited
Lysozyme-like0.00015460.2878Inherited
P-loop containing nucleoside triphosphate hydrolases0.00044560.04252Inherited


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Family

(show details)
SCOP termFDR (singleton)FDR (all)Annotation (direct or inherited)
Annexin0.00000000450.0003314Direct
Aquaporin-like0.0000001120.0001016Direct
Armadillo repeat0.00000027520.00003147Direct
Arp2/3 complex 16 kDa subunit ARPC50.00000034870.00001073Direct
C-type lysozyme0.00000020370.00004548Direct
Calmodulin-like0.000000000002920.00000000005752Direct
Calponin-homology domain, CH-domain0.00015150Direct
Cofilin-like0.00041720.00000000005275Direct
Cu,Zn superoxide dismutase-like0.00000000033350.00004947Direct
Defensin00.00000000009216Direct
G proteins00Direct
Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain0.0000013020.00000121Direct
Nucleoside diphosphate kinase, NDK0.00000075260.0000000469Direct
Parvalbumin0.00000010220.000008431Direct
Regulator of G-protein signaling, RGS0.00003260.00000000001851Direct
Retinol binding protein-like0.0000000063970.00001288Direct
Spectrin repeat0.0000000021090Direct
Stathmin0.00000012270.00004893Direct
Thioesterases0.00000076930.00004893Direct
Transducin (heterotrimeric G protein), gamma chain0.000029110.00000002119Direct
Fatty acid binding protein-like0.78911Inherited
Ribonuclease A-like0.0035810.07867Inherited
Rhodopsin-like0.041650.1249Inherited
Protein kinases, catalytic subunit0.00000000046670.01415Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this GO term
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Supra-domain (including individual superfamily)

(show details)
Supra-domain (Single) FDR (all) Annotation (direct or inherited)
GAS2 domain-like0Direct
Transducin (alpha subunit), insertion domain0Direct
C2 domain (Calcium/lipid-binding domain, CaLB)0Direct
Plakin repeat0Direct
BAR/IMD domain-like0Direct
SH3-domain0Direct
Cadherin-like0Direct
Second domain of FERM0Direct
Periplasmic binding protein-like I0Direct
Moesin tail domain0Direct
RGC domain-like0Direct
Ubiquitin-like0Direct
EGF/Laminin0Direct
Smp-1-like0Direct
Calponin-homology domain, CH-domain0Direct
cAMP-binding domain-like0Direct
(Phosphotyrosine protein) phosphatases II0Direct
EF-hand0Direct
RILP dimerisation region0Direct
Spectrin repeat0Direct
Cysteine-rich domain0.0000000000000016Direct
GTPase activation domain, GAP0.00000000000003658Direct
Integrin domains0.00000000000007875Direct
SAM/Pointed domain0.000000000000191Direct
Regulator of G-protein signaling, RGS0.0000000000004988Direct
Actin depolymerizing proteins0.000000000002098Direct
FAT domain of focal adhesion kinase0.000000000003431Direct
Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit0.000000000003881Direct
Doublecortin (DC)0.00000000000427Direct
Transducin (heterotrimeric G protein), gamma chain0.00000000001531Direct
Vasodilator-stimulated phosphoprotein, VASP, tetramerisation domain0.00000000004834Direct
NAD kinase/diacylglycerol kinase-like0.00000000005834Direct
Nucleotide cyclase0.0000000001036Direct
Outer arm dynein light chain 10.0000000001081Direct
Integrin beta tail domain0.0000000002308Direct
Acylphosphatase/BLUF domain-like0.0000000005584Direct
SNARE fusion complex0.000000001653Direct
Amyloid beta a4 protein copper binding domain (domain 2)0.000000001903Direct
A heparin-binding domain0.000000007873Direct
Nucleoside diphosphate kinase, NDK0.00000001259Direct
Tricorn protease domain 20.00000001422Direct
Myosin S1 fragment, N-terminal domain0.00000001932Direct
DEATH domain0.00000002005Direct
Sec7 domain0.00000002335Direct
CAPPD, an extracellular domain of amyloid beta A4 protein0.000000027Direct
Growth factor receptor domain0.0000000754Direct
Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain0.0000001356Direct
Defensin-like0.0000001835Direct
Rap/Ran-GAP0.0000002017Direct
VHP, Villin headpiece domain0.000000242Direct
Formin homology 2 domain (FH2 domain)0.0000009501Direct
L27 domain0.000002204Direct
Myosin rod fragments0.000002231Direct
Galactose-binding domain-like0.000002907Direct
alpha-catenin/vinculin-like0.0000051Direct
Cryptochrome/photolyase, N-terminal domain0.000005347Direct
Plexin repeat0.000005556Direct
Arp2/3 complex 16 kDa subunit ARPC50.000005687Direct
ARM repeat0.000009194Direct
POZ domain0.00001254Direct
Cryptochrome/photolyase FAD-binding domain0.00001353Direct
Hook domain0.00001574Direct
Cu,Zn superoxide dismutase-like0.00001954Direct
DPP6 N-terminal domain-like0.00002335Direct
Tropomyosin0.00002491Direct
Stathmin0.00002537Direct
Carboxypeptidase regulatory domain-like0.00003583Direct
Aquaporin-like0.00003702Direct
Integrin alpha N-terminal domain0.00004709Direct
SEA domain0.00005606Direct
N-terminal coiled coil domain from apc0.0000695Direct
Tumor suppressor gene product Apc0.0000695Direct
Composite domain of metallo-dependent hydrolases0.00007618Direct
DNase I-like0.00008713Direct
Periplasmic binding protein-like II0.000109Direct
Annexin0.0001303Direct
Cap-Gly domain0.0001373Direct
Small-conductance potassium channel0.0001577Direct
Spermadhesin, CUB domain0.000219Direct
Aromatic aminoacid monoxygenases, catalytic and oligomerization domains0.0002324Direct
VPS9 domain0.0002324Direct
t-snare proteins0.0003643Direct
I/LWEQ domain0.0004351Direct
RCC1/BLIP-II0.0004367Direct
SH2 domain0.0004703Direct
Lissencephaly-1 protein (Lis-1, PAF-AH alpha) N-terminal domain0.0005124Direct
Metal cation-transporting ATPase, ATP-binding domain N0.0008093Direct
Actin-crosslinking proteins0.0008699Direct
NAD(P)-linked oxidoreductase1Inherited
(Trans)glycosidases1Inherited
GAF domain-like0.4332Inherited
P-loop containing nucleoside triphosphate hydrolases0.03415Inherited
Family A G protein-coupled receptor-like0.04845Inherited
Lysozyme-like0.2412Inherited
Complement control module/SCR domain0.8068Inherited
TPR-like0.2296Inherited
beta-beta-alpha zinc fingers1Inherited
Cysteine proteinases1Inherited
RNA-binding domain, RBD1Inherited
DHS-like NAD/FAD-binding domain0.83Inherited
Glutathione synthetase ATP-binding domain-like0.03505Inherited
Activating enzymes of the ubiquitin-like proteins0.5377Inherited
Plant invertase/pectin methylesterase inhibitor0.001372Inherited
Cullin repeat-like0.1171Inherited
Pectin lyase-like0.5774Inherited
Nucleotide-diphospho-sugar transferases1Inherited
Calcium ATPase, transduction domain A0.002627Inherited
Calcium ATPase, transmembrane domain M0.005273Inherited
GST C-terminal domain-like1Inherited
HAD-like0.8469Inherited
Thioredoxin-like1Inherited
vWA-like1Inherited
alpha/beta-Hydrolases1Inherited
PX domain0.06429Inherited
Quinoprotein alcohol dehydrogenase-like1Inherited
Tubby C-terminal domain-like0.04479Inherited
HD-domain/PDEase-like0.0227Inherited
Nuclear receptor ligand-binding domain0.793Inherited
TNF receptor-like0.05919Inherited
Multidrug efflux transporter AcrB transmembrane domain0.2689Inherited
Synuclein0.004104Inherited
PH domain-like0.1002Inherited
Tudor/PWWP/MBT0.8559Inherited
Bromodomain1Inherited
CalX-like0.01562Inherited
Cystine-knot cytokines0.1976Inherited
Protein kinase-like (PK-like)0.006337Inherited
KA1-like0.005934Inherited
Ankyrin repeat0.1495Inherited
Invertebrate chitin-binding proteins0.1875Inherited
Ypt/Rab-GAP domain of gyp1p0.003154Inherited
Kringle-like0.02658Inherited
PHM/PNGase F0.004087Inherited
Proton glutamate symport protein0.9681Inherited
CRAL/TRIO domain0.02422Inherited
L domain-like0.9126Inherited
SpoIIaa-like0.005795Inherited
WD40 repeat-like0.0469Inherited
PDZ domain-like0.06551Inherited
FF domain0.01426Inherited
Anthrax protective antigen0.004104Inherited
Rhodanese/Cell cycle control phosphatase0.1101Inherited
Class I glutamine amidotransferase-like0.8679Inherited
Zn-dependent exopeptidases1Inherited
Aldolase1Inherited
Snake toxin-like0.7264Inherited
Kazal-type serine protease inhibitors0.004677Inherited
Thyroglobulin type-1 domain0.1464Inherited
Fibrinogen C-terminal domain-like0.9035Inherited
Neurophysin II0.002506Inherited
ENTH/VHS domain0.4987Inherited
Voltage-gated potassium channels0.03769Inherited
Immunoglobulin0.0269Inherited
Band 7/SPFH domain0.2238Inherited
TSP-1 type 1 repeat0.8718Inherited
FYVE/PHD zinc finger0.9887Inherited
Concanavalin A-like lectins/glucanases0.2252Inherited
SAICAR synthase-like0.8115Inherited
Cytochrome P4501Inherited
YWTD domain0.002917Inherited
SNF-like0.7817Inherited
MFS general substrate transporter1Inherited
ABC transporter transmembrane region1Inherited
GroES-like1Inherited
C-type lectin-like0.7092Inherited
Frizzled cysteine-rich domain0.001578Inherited
Metallo-dependent hydrolases0.1237Inherited
FKBP-like0.1796Inherited
DBL homology domain (DH-domain)0.8505Inherited
YVTN repeat-like/Quinoprotein amine dehydrogenase0.02373Inherited
RNase A-like0.05269Inherited
Metalloproteases ("zincins"), catalytic domain0.1958Inherited
Fibronectin type III0.009818Inherited
Transcription factor STAT-4 N-domain0.004803Inherited
STAT0.008256Inherited
Nicotinic receptor ligand binding domain-like0.2124Inherited
Neurotransmitter-gated ion-channel transmembrane pore0.2166Inherited
Polo-box domain0.00664Inherited
Hemopexin-like domain0.01635Inherited
Lipocalins0.6862Inherited
Alanine racemase C-terminal domain-like0.1038Inherited
Calpain large subunit, middle domain (domain III)0.006714Inherited
MoeA C-terminal domain-like0.01157Inherited
MoeA N-terminal region -like0.01285Inherited
PGBD-like0.04136Inherited
Molybdenum cofactor biosynthesis proteins0.06944Inherited
SRCR-like0.006484Inherited
BPTI-like0.0291Inherited
Intermediate filament protein, coiled coil region1Inherited
Actin-like ATPase domain0.258Inherited
4-helical cytokines1Inherited
RUN domain-like0.02752Inherited
Eukaryotic type KH-domain (KH-domain type I)0.01987Inherited
NHL repeat0.01649Inherited
C-terminal, gelsolin-like domain of Sec23/240.02027Inherited
beta-sandwich domain of Sec23/240.2711Inherited
Chromo domain-like0.9592Inherited
HR1 repeat0.07583Inherited
CAD & PB1 domains0.5446Inherited
PKD domain0.07094Inherited
Tetraspanin0.8773Inherited
G protein-binding domain0.002568Inherited
PLC-like phosphodiesterases0.2141Inherited
A middle domain of Talin 10.006097Inherited
Galactose oxidase, central domain0.3492Inherited
ArfGap/RecO-like zinc finger0.9519Inherited
FAD/NAD(P)-binding domain1Inherited

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
52799,52799
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 0Direct
    47473,143575
  • 47473 - EF-hand
  • 143575 - GAS2 domain-like
  • 0Direct
    52540,52540
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    46966,46966
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 0Direct
    49899,48726
  • 49899 - Concanavalin A-like lectins/glucanases
  • 48726 - Immunoglobulin
  • 0Direct
    54975,55073
  • 54975 - Acylphosphatase/BLUF domain-like
  • 55073 - Nucleotide cyclase
  • 0Direct
    57440,56487
  • 57440 - Kringle-like
  • 56487 - SRCR-like
  • 0Direct
    47473,47473
  • 47473 - EF-hand
  • 47473 - EF-hand
  • 0Direct
    48403,48403
  • 48403 - Ankyrin repeat
  • 48403 - Ankyrin repeat
  • 0Direct
    54236,47031
  • 54236 - Ubiquitin-like
  • 47031 - Second domain of FERM
  • 0Direct
    50985,48065
  • 50985 - RCC1/BLIP-II
  • 48065 - DBL homology domain (DH-domain)
  • 0Direct
    75399,46966
  • 75399 - Plakin repeat
  • 46966 - Spectrin repeat
  • 0Direct
    49265,48726
  • 49265 - Fibronectin type III
  • 48726 - Immunoglobulin
  • 0Direct
    50156,50156
  • 50156 - PDZ domain-like
  • 50156 - PDZ domain-like
  • 0Direct
    47895,52540
  • 47895 - Transducin (alpha subunit), insertion domain
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    50044,52540
  • 50044 - SH3-domain
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    46966,47473
  • 46966 - Spectrin repeat
  • 47473 - EF-hand
  • 0Direct
    50156,50044
  • 50156 - PDZ domain-like
  • 50044 - SH3-domain
  • 0Direct
    47031,50729
  • 47031 - Second domain of FERM
  • 50729 - PH domain-like
  • 0Direct
    81995,54236
  • 81995 - beta-sandwich domain of Sec23/24
  • 54236 - Ubiquitin-like
  • 0Direct
    49265,49265
  • 49265 - Fibronectin type III
  • 49265 - Fibronectin type III
  • 0Direct
    55073,52047
  • 55073 - Nucleotide cyclase
  • 52047 - RNI-like
  • 0Direct
    49313,49313
  • 49313 - Cadherin-like
  • 49313 - Cadherin-like
  • 0.000000000000002394Direct
    81324,53850
  • 81324 - Voltage-gated potassium channels
  • 53850 - Periplasmic binding protein-like II
  • 0.00000000000002228Direct
    89837,89837
  • 89837 - Doublecortin (DC)
  • 89837 - Doublecortin (DC)
  • 0.00000000000006546Direct
    50044,50156
  • 50044 - SH3-domain
  • 50156 - PDZ domain-like
  • 0.0000000000005037Direct
    47576,46966
  • 47576 - Calponin-homology domain, CH-domain
  • 46966 - Spectrin repeat
  • 0.000000000002347Direct
    47473,57610
  • 47473 - EF-hand
  • 57610 - Thyroglobulin type-1 domain
  • 0.000000000002605Direct
    49785,49899
  • 49785 - Galactose-binding domain-like
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.000000000005054Direct
    48670,48097
  • 48670 - Transducin (heterotrimeric G protein), gamma chain
  • 48097 - Regulator of G-protein signaling, RGS
  • 0.000000000006345Direct
    57196,56496
  • 57196 - EGF/Laminin
  • 56496 - Fibrinogen C-terminal domain-like
  • 0.00000000001199Direct
    56496,49899
  • 56496 - Fibrinogen C-terminal domain-like
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.00000000001199Direct
    50729,50729
  • 50729 - PH domain-like
  • 50729 - PH domain-like
  • 0.00000000001297Direct
    56112,47769
  • 56112 - Protein kinase-like (PK-like)
  • 47769 - SAM/Pointed domain
  • 0.0000000000216Direct
    57362,109843
  • 57362 - BPTI-like
  • 109843 - CAPPD, an extracellular domain of amyloid beta A4 protein
  • 0.00000000004834Direct
    50978,69322
  • 50978 - WD40 repeat-like
  • 69322 - Tricorn protease domain 2
  • 0.0000000002052Direct
    57889,50729
  • 57889 - Cysteine-rich domain
  • 50729 - PH domain-like
  • 0.0000000002383Direct
    49899,57196
  • 49899 - Concanavalin A-like lectins/glucanases
  • 57196 - EGF/Laminin
  • 0.0000000003872Direct
    53300,69179
  • 53300 - vWA-like
  • 69179 - Integrin domains
  • 0.0000000003949Direct
    47769,47769
  • 47769 - SAM/Pointed domain
  • 47769 - SAM/Pointed domain
  • 0.000000000659Direct
    57196,69687
  • 57196 - EGF/Laminin
  • 69687 - Integrin beta tail domain
  • 0.000000001403Direct
    56491,89811
  • 56491 - A heparin-binding domain
  • 89811 - Amyloid beta a4 protein copper binding domain (domain 2)
  • 0.000000001903Direct
    82754,82754
  • 82754 - C-terminal, gelsolin-like domain of Sec23/24
  • 82754 - C-terminal, gelsolin-like domain of Sec23/24
  • 0.000000002675Direct
    48452,48452
  • 48452 - TPR-like
  • 48452 - TPR-like
  • 0.000000005045Direct
    47769,52200
  • 47769 - SAM/Pointed domain
  • 52200 - Toll/Interleukin receptor TIR domain
  • 0.000000005653Direct
    48371,47769
  • 48371 - ARM repeat
  • 47769 - SAM/Pointed domain
  • 0.000000005653Direct
    48425,50729
  • 48425 - Sec7 domain
  • 50729 - PH domain-like
  • 0.000000006422Direct
    49562,49562
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 0.000000007726Direct
    51556,51338
  • 51556 - Metallo-dependent hydrolases
  • 51338 - Composite domain of metallo-dependent hydrolases
  • 0.00000001141Direct
    46966,51045
  • 46966 - Spectrin repeat
  • 51045 - WW domain
  • 0.00000005872Direct
    57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.00000009099Direct
    46966,50044
  • 46966 - Spectrin repeat
  • 50044 - SH3-domain
  • 0.00000009109Direct
    51045,47473
  • 51045 - WW domain
  • 47473 - EF-hand
  • 0.00000009191Direct
    55073,55073
  • 55073 - Nucleotide cyclase
  • 55073 - Nucleotide cyclase
  • 0.000000151Direct
    50729,82185
  • 50729 - PH domain-like
  • 82185 - Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain
  • 0.000000151Direct
    49265,49899
  • 49265 - Fibronectin type III
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.0000002184Direct
    56219,54928
  • 56219 - DNase I-like
  • 54928 - RNA-binding domain, RBD
  • 0.0000002242Direct
    50156,103657
  • 50156 - PDZ domain-like
  • 103657 - BAR/IMD domain-like
  • 0.0000002242Direct
    54236,48366
  • 54236 - Ubiquitin-like
  • 48366 - Ras GEF
  • 0.000000302Direct
    55753,47050
  • 55753 - Actin depolymerizing proteins
  • 47050 - VHP, Villin headpiece domain
  • 0.000000302Direct
    48726,57196
  • 48726 - Immunoglobulin
  • 57196 - EGF/Laminin
  • 0.0000003297Direct
    47576,50044
  • 47576 - Calponin-homology domain, CH-domain
  • 50044 - SH3-domain
  • 0.0000003604Direct
    48097,56112
  • 48097 - Regulator of G-protein signaling, RGS
  • 56112 - Protein kinase-like (PK-like)
  • 0.0000003639Direct
    100895,47473
  • 100895 - Kazal-type serine protease inhibitors
  • 47473 - EF-hand
  • 0.0000004415Direct
    54791,54791
  • 54791 - Eukaryotic type KH-domain (KH-domain type I)
  • 54791 - Eukaryotic type KH-domain (KH-domain type I)
  • 0.0000006318Direct
    55550,56112
  • 55550 - SH2 domain
  • 56112 - Protein kinase-like (PK-like)
  • 0.0000006865Direct
    56112,90257
  • 56112 - Protein kinase-like (PK-like)
  • 90257 - Myosin rod fragments
  • 0.0000008076Direct
    74924,54001
  • 74924 - Cap-Gly domain
  • 54001 - Cysteine proteinases
  • 0.0000008386Direct
    50978,48452
  • 50978 - WD40 repeat-like
  • 48452 - TPR-like
  • 0.0000008386Direct
    74924,74924
  • 74924 - Cap-Gly domain
  • 74924 - Cap-Gly domain
  • 0.000001442Direct
    49854,49854
  • 49854 - Spermadhesin, CUB domain
  • 49854 - Spermadhesin, CUB domain
  • 0.00000163Direct
    56487,56487
  • 56487 - SRCR-like
  • 56487 - SRCR-like
  • 0.000001769Direct
    48350,50044
  • 48350 - GTPase activation domain, GAP
  • 50044 - SH3-domain
  • 0.00000202Direct
    57196,63825
  • 57196 - EGF/Laminin
  • 63825 - YWTD domain
  • 0.000002167Direct
    47220,47220
  • 47220 - alpha-catenin/vinculin-like
  • 47220 - alpha-catenin/vinculin-like
  • 0.000002198Direct
    56112,50985
  • 56112 - Protein kinase-like (PK-like)
  • 50985 - RCC1/BLIP-II
  • 0.00000259Direct
    56988,81296
  • 56988 - Anthrax protective antigen
  • 81296 - E set domains
  • 0.00000259Direct
    57184,49265
  • 57184 - Growth factor receptor domain
  • 49265 - Fibronectin type III
  • 0.00000262Direct
    81324,47473
  • 81324 - Voltage-gated potassium channels
  • 47473 - EF-hand
  • 0.000003129Direct
    56487,50494
  • 56487 - SRCR-like
  • 50494 - Trypsin-like serine proteases
  • 0.000003191Direct
    47473,57850
  • 47473 - EF-hand
  • 57850 - RING/U-box
  • 0.000003271Direct
    82185,82185
  • 82185 - Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain
  • 82185 - Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain
  • 0.000003271Direct
    52425,48173
  • 52425 - Cryptochrome/photolyase, N-terminal domain
  • 48173 - Cryptochrome/photolyase FAD-binding domain
  • 0.000003465Direct
    50044,55550
  • 50044 - SH3-domain
  • 55550 - SH2 domain
  • 0.000003625Direct
    56112,50998
  • 56112 - Protein kinase-like (PK-like)
  • 50998 - Quinoprotein alcohol dehydrogenase-like
  • 0.000003928Direct
    56112,101288
  • 56112 - Protein kinase-like (PK-like)
  • 101288 - L27 domain
  • 0.000003928Direct
    50044,46966
  • 50044 - SH3-domain
  • 46966 - Spectrin repeat
  • 0.000003978Direct
    55753,55753
  • 55753 - Actin depolymerizing proteins
  • 55753 - Actin depolymerizing proteins
  • 0.000004933Direct
    55073,52540
  • 55073 - Nucleotide cyclase
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.000006393Direct
    81296,56988
  • 81296 - E set domains
  • 56988 - Anthrax protective antigen
  • 0.000006393Direct
    55753,82754
  • 55753 - Actin depolymerizing proteins
  • 82754 - C-terminal, gelsolin-like domain of Sec23/24
  • 0.000007341Direct
    69179,69179
  • 69179 - Integrin domains
  • 69179 - Integrin domains
  • 0.000007801Direct
    50044,48065
  • 50044 - SH3-domain
  • 48065 - DBL homology domain (DH-domain)
  • 0.00001097Direct
    57889,57889
  • 57889 - Cysteine-rich domain
  • 57889 - Cysteine-rich domain
  • 0.00001459Direct
    50405,50405
  • 50405 - Actin-crosslinking proteins
  • 50405 - Actin-crosslinking proteins
  • 0.00001484Direct
    63825,57196
  • 63825 - YWTD domain
  • 57196 - EGF/Laminin
  • 0.00001574Direct
    50729,69322
  • 50729 - PH domain-like
  • 69322 - Tricorn protease domain 2
  • 0.00001757Direct
    53822,53850
  • 53822 - Periplasmic binding protein-like I
  • 53850 - Periplasmic binding protein-like II
  • 0.0000202Direct
    101288,50156
  • 101288 - L27 domain
  • 50156 - PDZ domain-like
  • 0.00002216Direct
    69318,69179
  • 69318 - Integrin alpha N-terminal domain
  • 69179 - Integrin domains
  • 0.00002283Direct
    54919,54919
  • 54919 - Nucleoside diphosphate kinase, NDK
  • 54919 - Nucleoside diphosphate kinase, NDK
  • 0.00002506Direct
    82754,55753
  • 82754 - C-terminal, gelsolin-like domain of Sec23/24
  • 55753 - Actin depolymerizing proteins
  • 0.00002583Direct
    51338,51556
  • 51338 - Composite domain of metallo-dependent hydrolases
  • 51556 - Metallo-dependent hydrolases
  • 0.00002905Direct
    49785,57184
  • 49785 - Galactose-binding domain-like
  • 57184 - Growth factor receptor domain
  • 0.00003553Direct
    50978,47473
  • 50978 - WD40 repeat-like
  • 47473 - EF-hand
  • 0.00004788Direct
    57184,63825
  • 57184 - Growth factor receptor domain
  • 63825 - YWTD domain
  • 0.00006521Direct
    57424,57184
  • 57424 - LDL receptor-like module
  • 57184 - Growth factor receptor domain
  • 0.00006794Direct
    117281,50965
  • 117281 - Kelch motif
  • 50965 - Galactose oxidase, central domain
  • 0.0000695Direct
    49854,49785
  • 49854 - Spermadhesin, CUB domain
  • 49785 - Galactose-binding domain-like
  • 0.00007209Direct
    54534,54534
  • 54534 - FKBP-like
  • 54534 - FKBP-like
  • 0.00009101Direct
    50939,50939
  • 50939 - Sialidases
  • 50939 - Sialidases
  • 0.0001036Direct
    64268,50729
  • 64268 - PX domain
  • 50729 - PH domain-like
  • 0.0001069Direct
    46966,50729
  • 46966 - Spectrin repeat
  • 50729 - PH domain-like
  • 0.0001069Direct
    50729,56112
  • 50729 - PH domain-like
  • 56112 - Protein kinase-like (PK-like)
  • 0.0001119Direct
    49562,48371
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 48371 - ARM repeat
  • 0.000144Direct
    81324,81327
  • 81324 - Voltage-gated potassium channels
  • 81327 - Small-conductance potassium channel
  • 0.0001577Direct
    50978,50978
  • 50978 - WD40 repeat-like
  • 50978 - WD40 repeat-like
  • 0.0001602Direct
    101288,101288
  • 101288 - L27 domain
  • 101288 - L27 domain
  • 0.0001933Direct
    100909,48371
  • 100909 - IP3 receptor type 1 binding core, domain 2
  • 48371 - ARM repeat
  • 0.0001933Direct
    50044,50729
  • 50044 - SH3-domain
  • 50729 - PH domain-like
  • 0.0001933Direct
    49562,50729
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 50729 - PH domain-like
  • 0.0001933Direct
    161111,160240
  • 161111 - Cation efflux protein transmembrane domain-like
  • 160240 - Cation efflux protein cytoplasmic domain-like
  • 0.0002097Direct
    52540,48452
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 48452 - TPR-like
  • 0.0002242Direct
    50729,50044
  • 50729 - PH domain-like
  • 50044 - SH3-domain
  • 0.0002436Direct
    56112,55073
  • 56112 - Protein kinase-like (PK-like)
  • 55073 - Nucleotide cyclase
  • 0.0002436Direct
    54236,50729
  • 54236 - Ubiquitin-like
  • 50729 - PH domain-like
  • 0.0002534Direct
    57889,49562
  • 57889 - Cysteine-rich domain
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 0.000268Direct
    82171,53474
  • 82171 - DPP6 N-terminal domain-like
  • 53474 - alpha/beta-Hydrolases
  • 0.0002685Direct
    47220,109885
  • 47220 - alpha-catenin/vinculin-like
  • 109885 - I/LWEQ domain
  • 0.00031Direct
    82171,50978
  • 82171 - DPP6 N-terminal domain-like
  • 50978 - WD40 repeat-like
  • 0.0003261Direct
    103473,141571
  • 103473 - MFS general substrate transporter
  • 141571 - Pentapeptide repeat-like
  • 0.0003261Direct
    50729,56024
  • 50729 - PH domain-like
  • 56024 - Phospholipase D/nuclease
  • 0.0004181Direct
    49758,47473
  • 49758 - Calpain large subunit, middle domain (domain III)
  • 47473 - EF-hand
  • 0.0004351Direct
    49562,48350
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 48350 - GTPase activation domain, GAP
  • 0.0004351Direct
    49562,56112
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 56112 - Protein kinase-like (PK-like)
  • 0.0004389Direct
    109925,50978
  • 109925 - Lissencephaly-1 protein (Lis-1, PAF-AH alpha) N-terminal domain
  • 50978 - WD40 repeat-like
  • 0.0005124Direct
    51045,50156
  • 51045 - WW domain
  • 50156 - PDZ domain-like
  • 0.0005531Direct
    64356,58038
  • 64356 - SNARE-like
  • 58038 - SNARE fusion complex
  • 0.000649Direct
    50044,51695
  • 50044 - SH3-domain
  • 51695 - PLC-like phosphodiesterases
  • 0.0007166Direct
    57716,50156
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 50156 - PDZ domain-like
  • 0.0007602Direct
    56112,50978
  • 56112 - Protein kinase-like (PK-like)
  • 50978 - WD40 repeat-like
  • 0.0007602Direct
    82615,82615
  • 82615 - Polo-box domain
  • 82615 - Polo-box domain
  • 0.0008699Direct
    50729,49562
  • 50729 - PH domain-like
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 0.0009087Direct
    101148,51126
  • 101148 - Plant invertase/pectin methylesterase inhibitor
  • 51126 - Pectin lyase-like
  • 0.0009087Direct
    57196,57184
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 0.02132Inherited
    55781,109604
  • 55781 - GAF domain-like
  • 109604 - HD-domain/PDEase-like
  • 0.00838Inherited
    55781,55781
  • 55781 - GAF domain-like
  • 55781 - GAF domain-like
  • 0.018Inherited
    57535,57535
  • 57535 - Complement control module/SCR domain
  • 57535 - Complement control module/SCR domain
  • 0.7233Inherited
    57667,57667
  • 57667 - beta-beta-alpha zinc fingers
  • 57667 - beta-beta-alpha zinc fingers
  • 1Inherited
    56112,48371
  • 56112 - Protein kinase-like (PK-like)
  • 48371 - ARM repeat
  • 0.007371Inherited
    52058,56112
  • 52058 - L domain-like
  • 56112 - Protein kinase-like (PK-like)
  • 0.003825Inherited
    56784,81665
  • 56784 - HAD-like
  • 81665 - Calcium ATPase, transmembrane domain M
  • 0.001381Inherited
    81660,56784
  • 81660 - Metal cation-transporting ATPase, ATP-binding domain N
  • 56784 - HAD-like
  • 0.001262Inherited
    52833,47616
  • 52833 - Thioredoxin-like
  • 47616 - GST C-terminal domain-like
  • 0.9959Inherited
    64268,103657
  • 64268 - PX domain
  • 103657 - BAR/IMD domain-like
  • 0.003338Inherited
    49899,49899
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.7262Inherited
    51206,51206
  • 51206 - cAMP-binding domain-like
  • 51206 - cAMP-binding domain-like
  • 0.02598Inherited
    53850,81324
  • 53850 - Periplasmic binding protein-like II
  • 81324 - Voltage-gated potassium channels
  • 0.002565Inherited
    57903,47370
  • 57903 - FYVE/PHD zinc finger
  • 47370 - Bromodomain
  • 0.04226Inherited
    47370,63748
  • 47370 - Bromodomain
  • 63748 - Tudor/PWWP/MBT
  • 0.002565Inherited
    47661,58038
  • 47661 - t-snare proteins
  • 58038 - SNARE fusion complex
  • 0.008155Inherited
    47923,47923
  • 47923 - Ypt/Rab-GAP domain of gyp1p
  • 47923 - Ypt/Rab-GAP domain of gyp1p
  • 0.3266Inherited
    141072,141072
  • 141072 - CalX-like
  • 141072 - CalX-like
  • 0.004225Inherited
    54236,54236
  • 54236 - Ubiquitin-like
  • 54236 - Ubiquitin-like
  • 0.009352Inherited
    57196,100895
  • 57196 - EGF/Laminin
  • 100895 - Kazal-type serine protease inhibitors
  • 0.001974Inherited
    55021,56534
  • 55021 - ACT-like
  • 56534 - Aromatic aminoacid monoxygenases, catalytic and oligomerization domains
  • 0.002198Inherited
    49562,53300
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 53300 - vWA-like
  • 0.002236Inherited
    49742,49742
  • 49742 - PHM/PNGase F
  • 49742 - PHM/PNGase F
  • 0.004087Inherited
    52058,48726
  • 52058 - L domain-like
  • 48726 - Immunoglobulin
  • 0.01212Inherited
    54768,54768
  • 54768 - dsRNA-binding domain-like
  • 54768 - dsRNA-binding domain-like
  • 0.01506Inherited
    81296,81296
  • 81296 - E set domains
  • 81296 - E set domains
  • 0.004073Inherited
    54928,54928
  • 54928 - RNA-binding domain, RBD
  • 54928 - RNA-binding domain, RBD
  • 1Inherited
    48726,82895
  • 48726 - Immunoglobulin
  • 82895 - TSP-1 type 1 repeat
  • 0.02793Inherited
    48726,48726
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 0.07442Inherited
    57424,57196
  • 57424 - LDL receptor-like module
  • 57196 - EGF/Laminin
  • 0.01285Inherited
    57424,57424
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 0.06023Inherited
    52540,90123
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 90123 - ABC transporter transmembrane region
  • 0.4057Inherited
    90123,52540
  • 90123 - ABC transporter transmembrane region
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.9941Inherited
    50129,51735
  • 50129 - GroES-like
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 1Inherited
    57196,49854
  • 57196 - EGF/Laminin
  • 49854 - Spermadhesin, CUB domain
  • 0.03157Inherited
    48371,56112
  • 48371 - ARM repeat
  • 56112 - Protein kinase-like (PK-like)
  • 0.001149Inherited
    57716,57716
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 0.6567Inherited
    48065,50729
  • 48065 - DBL homology domain (DH-domain)
  • 50729 - PH domain-like
  • 0.8736Inherited
    52058,52058
  • 52058 - L domain-like
  • 52058 - L domain-like
  • 0.1002Inherited
    54534,48452
  • 54534 - FKBP-like
  • 48452 - TPR-like
  • 0.001558Inherited
    48726,49265
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 0.07233Inherited
    48092,47655
  • 48092 - Transcription factor STAT-4 N-domain
  • 47655 - STAT
  • 0.00447Inherited
    49417,55550
  • 49417 - p53-like transcription factors
  • 55550 - SH2 domain
  • 0.00553Inherited
    47655,49417
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 0.005934Inherited
    63712,90112
  • 63712 - Nicotinic receptor ligand binding domain-like
  • 90112 - Neurotransmitter-gated ion-channel transmembrane pore
  • 0.2166Inherited
    55486,50923
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 50923 - Hemopexin-like domain
  • 0.005158Inherited
    47090,55486
  • 47090 - PGBD-like
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 0.007377Inherited
    52058,52540
  • 52058 - L domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.006097Inherited
    51419,50621
  • 51419 - PLP-binding barrel
  • 50621 - Alanine racemase C-terminal domain-like
  • 0.06944Inherited
    53218,63867
  • 53218 - Molybdenum cofactor biosynthesis proteins
  • 63867 - MoeA C-terminal domain-like
  • 0.01157Inherited
    63882,53218
  • 63882 - MoeA N-terminal region -like
  • 53218 - Molybdenum cofactor biosynthesis proteins
  • 0.01285Inherited
    69572,69572
  • 69572 - Activating enzymes of the ubiquitin-like proteins
  • 69572 - Activating enzymes of the ubiquitin-like proteins
  • 0.02514Inherited
    50156,52540
  • 50156 - PDZ domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 1Inherited
    52540,51045
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 51045 - WW domain
  • 1Inherited
    75399,75399
  • 75399 - Plakin repeat
  • 75399 - Plakin repeat
  • 0.001221Inherited
    47060,55681
  • 47060 - S15/NS1 RNA-binding domain
  • 55681 - Class II aaRS and biotin synthetases
  • 0.006097Inherited
    49785,49785
  • 49785 - Galactose-binding domain-like
  • 49785 - Galactose-binding domain-like
  • 0.07533Inherited
    53067,53067
  • 53067 - Actin-like ATPase domain
  • 53067 - Actin-like ATPase domain
  • 0.258Inherited
    50729,52799
  • 50729 - PH domain-like
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 0.005767Inherited
    57184,57196
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 0.01911Inherited
    46585,46585
  • 46585 - HR1 repeat
  • 46585 - HR1 repeat
  • 0.001479Inherited
    49299,49299
  • 49299 - PKD domain
  • 49299 - PKD domain
  • 0.004104Inherited
    56112,50729
  • 56112 - Protein kinase-like (PK-like)
  • 50729 - PH domain-like
  • 1Inherited
    90257,90257
  • 90257 - Myosin rod fragments
  • 90257 - Myosin rod fragments
  • 0.008291Inherited
    50729,57889
  • 50729 - PH domain-like
  • 57889 - Cysteine-rich domain
  • 0.00536Inherited
    55550,50044
  • 55550 - SH2 domain
  • 50044 - SH3-domain
  • 0.02744Inherited
    55550,55550
  • 55550 - SH2 domain
  • 55550 - SH2 domain
  • 0.06555Inherited
    57863,48403
  • 57863 - ArfGap/RecO-like zinc finger
  • 48403 - Ankyrin repeat
  • 0.003826Inherited
    109880,109885
  • 109880 - A middle domain of Talin 1
  • 109885 - I/LWEQ domain
  • 0.006097Inherited
    50729,57863
  • 50729 - PH domain-like
  • 57863 - ArfGap/RecO-like zinc finger
  • 0.00664Inherited
    109885,109885
  • 109885 - I/LWEQ domain
  • 109885 - I/LWEQ domain
  • 0.00867Inherited
    50729,47473
  • 50729 - PH domain-like
  • 47473 - EF-hand
  • 0.009405Inherited
    51695,49562
  • 51695 - PLC-like phosphodiesterases
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 0.0445Inherited
    55550,50729
  • 55550 - SH2 domain
  • 50729 - PH domain-like
  • 0.05706Inherited
    50729,57903
  • 50729 - PH domain-like
  • 57903 - FYVE/PHD zinc finger
  • 1Inherited
    57903,50729
  • 57903 - FYVE/PHD zinc finger
  • 50729 - PH domain-like
  • 1Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    81995,54236,50729
  • 81995 - beta-sandwich domain of Sec23/24
  • 54236 - Ubiquitin-like
  • 50729 - PH domain-like
  • 0Direct
    54236,47031,50729
  • 54236 - Ubiquitin-like
  • 47031 - Second domain of FERM
  • 50729 - PH domain-like
  • 0Direct
    46966,47473,47473
  • 46966 - Spectrin repeat
  • 47473 - EF-hand
  • 47473 - EF-hand
  • 0Direct
    75399,46966,46966
  • 75399 - Plakin repeat
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 0Direct
    54975,55073,52047
  • 54975 - Acylphosphatase/BLUF domain-like
  • 55073 - Nucleotide cyclase
  • 52047 - RNI-like
  • 0Direct
    48065,50729,82185
  • 48065 - DBL homology domain (DH-domain)
  • 50729 - PH domain-like
  • 82185 - Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain
  • 0Direct
    56487,56487,50494
  • 56487 - SRCR-like
  • 56487 - SRCR-like
  • 50494 - Trypsin-like serine proteases
  • 0Direct
    49265,48726,49265
  • 49265 - Fibronectin type III
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 0Direct
    57440,56487,56487
  • 57440 - Kringle-like
  • 56487 - SRCR-like
  • 56487 - SRCR-like
  • 0Direct
    50978,50978,48452
  • 50978 - WD40 repeat-like
  • 50978 - WD40 repeat-like
  • 48452 - TPR-like
  • 0Direct
    54919,54919,54919
  • 54919 - Nucleoside diphosphate kinase, NDK
  • 54919 - Nucleoside diphosphate kinase, NDK
  • 54919 - Nucleoside diphosphate kinase, NDK
  • 0Direct
    46966,46966,47473
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 47473 - EF-hand
  • 0Direct
    50985,48065,50729
  • 50985 - RCC1/BLIP-II
  • 48065 - DBL homology domain (DH-domain)
  • 50729 - PH domain-like
  • 0Direct
    52540,52540,52540
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    46966,46966,46966
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 0Direct
    50156,50044,52540
  • 50156 - PDZ domain-like
  • 50044 - SH3-domain
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    49899,48726,49265
  • 49899 - Concanavalin A-like lectins/glucanases
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 0Direct
    49313,49313,49313
  • 49313 - Cadherin-like
  • 49313 - Cadherin-like
  • 49313 - Cadherin-like
  • 0.0000000000000016Direct
    47576,46966,46966
  • 47576 - Calponin-homology domain, CH-domain
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 0.0000000000002549Direct
    100895,47473,57610
  • 100895 - Kazal-type serine protease inhibitors
  • 47473 - EF-hand
  • 57610 - Thyroglobulin type-1 domain
  • 0.000000000002053Direct
    49899,57196,56496
  • 49899 - Concanavalin A-like lectins/glucanases
  • 57196 - EGF/Laminin
  • 56496 - Fibrinogen C-terminal domain-like
  • 0.00000000001199Direct
    56496,49899,49899
  • 56496 - Fibrinogen C-terminal domain-like
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.00000000001199Direct
    57196,56496,49899
  • 57196 - EGF/Laminin
  • 56496 - Fibrinogen C-terminal domain-like
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.00000000001199Direct
    48065,50729,50729
  • 48065 - DBL homology domain (DH-domain)
  • 50729 - PH domain-like
  • 50729 - PH domain-like
  • 0.00000000001916Direct
    51338,51556,51338
  • 51338 - Composite domain of metallo-dependent hydrolases
  • 51556 - Metallo-dependent hydrolases
  • 51338 - Composite domain of metallo-dependent hydrolases
  • 0.00000000002071Direct
    48726,49265,49265
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 49265 - Fibronectin type III
  • 0.00000000003795Direct
    49785,49899,49899
  • 49785 - Galactose-binding domain-like
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.00000000004499Direct
    57196,57196,69687
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 69687 - Integrin beta tail domain
  • 0.0000000006195Direct
    55753,82754,82754
  • 55753 - Actin depolymerizing proteins
  • 82754 - C-terminal, gelsolin-like domain of Sec23/24
  • 82754 - C-terminal, gelsolin-like domain of Sec23/24
  • 0.000000002675Direct
    82754,82754,55753
  • 82754 - C-terminal, gelsolin-like domain of Sec23/24
  • 82754 - C-terminal, gelsolin-like domain of Sec23/24
  • 55753 - Actin depolymerizing proteins
  • 0.000000002675Direct
    47769,47769,52200
  • 47769 - SAM/Pointed domain
  • 47769 - SAM/Pointed domain
  • 52200 - Toll/Interleukin receptor TIR domain
  • 0.000000005653Direct
    48371,47769,47769
  • 48371 - ARM repeat
  • 47769 - SAM/Pointed domain
  • 47769 - SAM/Pointed domain
  • 0.000000005653Direct
    50156,50156,50156
  • 50156 - PDZ domain-like
  • 50156 - PDZ domain-like
  • 50156 - PDZ domain-like
  • 0.00000001705Direct
    46966,46966,51045
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 51045 - WW domain
  • 0.00000003647Direct
    46966,51045,47473
  • 46966 - Spectrin repeat
  • 51045 - WW domain
  • 47473 - EF-hand
  • 0.00000005872Direct
    47220,47220,47220
  • 47220 - alpha-catenin/vinculin-like
  • 47220 - alpha-catenin/vinculin-like
  • 47220 - alpha-catenin/vinculin-like
  • 0.00000006595Direct
    46966,46966,50044
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 50044 - SH3-domain
  • 0.00000009109Direct
    51045,47473,47473
  • 51045 - WW domain
  • 47473 - EF-hand
  • 47473 - EF-hand
  • 0.00000009191Direct
    50729,50729,50729
  • 50729 - PH domain-like
  • 50729 - PH domain-like
  • 50729 - PH domain-like
  • 0.0000001306Direct
    55073,55073,52540
  • 55073 - Nucleotide cyclase
  • 55073 - Nucleotide cyclase
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.000000151Direct
    50729,82185,82185
  • 50729 - PH domain-like
  • 82185 - Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain
  • 82185 - Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain
  • 0.000000151Direct
    50044,55550,56112
  • 50044 - SH3-domain
  • 55550 - SH2 domain
  • 56112 - Protein kinase-like (PK-like)
  • 0.0000002489Direct
    55753,55753,47050
  • 55753 - Actin depolymerizing proteins
  • 55753 - Actin depolymerizing proteins
  • 47050 - VHP, Villin headpiece domain
  • 0.000000302Direct
    47576,50044,48065
  • 47576 - Calponin-homology domain, CH-domain
  • 50044 - SH3-domain
  • 48065 - DBL homology domain (DH-domain)
  • 0.0000003604Direct
    56487,56487,56487
  • 56487 - SRCR-like
  • 56487 - SRCR-like
  • 56487 - SRCR-like
  • 0.0000003639Direct
    101288,50156,50044
  • 101288 - L27 domain
  • 50156 - PDZ domain-like
  • 50044 - SH3-domain
  • 0.0000007671Direct
    49785,57184,49265
  • 49785 - Galactose-binding domain-like
  • 57184 - Growth factor receptor domain
  • 49265 - Fibronectin type III
  • 0.00000202Direct
    63825,57196,63825
  • 63825 - YWTD domain
  • 57196 - EGF/Laminin
  • 63825 - YWTD domain
  • 0.00000206Direct
    56988,81296,81296
  • 56988 - Anthrax protective antigen
  • 81296 - E set domains
  • 81296 - E set domains
  • 0.00000259Direct
    81296,56988,81296
  • 81296 - E set domains
  • 56988 - Anthrax protective antigen
  • 81296 - E set domains
  • 0.00000259Direct
    57196,57196,49854
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 49854 - Spermadhesin, CUB domain
  • 0.00000259Direct
    82754,55753,55753
  • 82754 - C-terminal, gelsolin-like domain of Sec23/24
  • 55753 - Actin depolymerizing proteins
  • 55753 - Actin depolymerizing proteins
  • 0.000002707Direct
    69179,69179,69179
  • 69179 - Integrin domains
  • 69179 - Integrin domains
  • 69179 - Integrin domains
  • 0.000002931Direct
    49899,57196,57184
  • 49899 - Concanavalin A-like lectins/glucanases
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 0.000003246Direct
    47473,47473,57850
  • 47473 - EF-hand
  • 47473 - EF-hand
  • 57850 - RING/U-box
  • 0.000003271Direct
    56112,101288,101288
  • 56112 - Protein kinase-like (PK-like)
  • 101288 - L27 domain
  • 101288 - L27 domain
  • 0.000003928Direct
    57196,57196,100895
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 100895 - Kazal-type serine protease inhibitors
  • 0.000003928Direct
    46966,50044,46966
  • 46966 - Spectrin repeat
  • 50044 - SH3-domain
  • 46966 - Spectrin repeat
  • 0.000003978Direct
    57889,57889,49562
  • 57889 - Cysteine-rich domain
  • 57889 - Cysteine-rich domain
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 0.000005536Direct
    50044,48065,50729
  • 50044 - SH3-domain
  • 48065 - DBL homology domain (DH-domain)
  • 50729 - PH domain-like
  • 0.000006153Direct
    54534,54534,48452
  • 54534 - FKBP-like
  • 54534 - FKBP-like
  • 48452 - TPR-like
  • 0.000009834Direct
    52540,48452,48452
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 48452 - TPR-like
  • 48452 - TPR-like
  • 0.0000134Direct
    50405,50405,50405
  • 50405 - Actin-crosslinking proteins
  • 50405 - Actin-crosslinking proteins
  • 50405 - Actin-crosslinking proteins
  • 0.00001484Direct
    57889,50729,69322
  • 57889 - Cysteine-rich domain
  • 50729 - PH domain-like
  • 69322 - Tricorn protease domain 2
  • 0.00001757Direct
    49899,49899,57196
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49899 - Concanavalin A-like lectins/glucanases
  • 57196 - EGF/Laminin
  • 0.00002216Direct
    57889,57889,57889
  • 57889 - Cysteine-rich domain
  • 57889 - Cysteine-rich domain
  • 57889 - Cysteine-rich domain
  • 0.00002249Direct
    69318,69179,69179
  • 69318 - Integrin alpha N-terminal domain
  • 69179 - Integrin domains
  • 69179 - Integrin domains
  • 0.00002283Direct
    49854,49854,49854
  • 49854 - Spermadhesin, CUB domain
  • 49854 - Spermadhesin, CUB domain
  • 49854 - Spermadhesin, CUB domain
  • 0.00003289Direct
    48403,48403,48403
  • 48403 - Ankyrin repeat
  • 48403 - Ankyrin repeat
  • 48403 - Ankyrin repeat
  • 0.00004007Direct
    48452,48452,48452
  • 48452 - TPR-like
  • 48452 - TPR-like
  • 48452 - TPR-like
  • 0.00004019Direct
    57424,57424,57184
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 57184 - Growth factor receptor domain
  • 0.00004059Direct
    57424,57184,63825
  • 57424 - LDL receptor-like module
  • 57184 - Growth factor receptor domain
  • 63825 - YWTD domain
  • 0.00004634Direct
    48065,50729,50044
  • 48065 - DBL homology domain (DH-domain)
  • 50729 - PH domain-like
  • 50044 - SH3-domain
  • 0.00004934Direct
    49854,49785,49785
  • 49854 - Spermadhesin, CUB domain
  • 49785 - Galactose-binding domain-like
  • 49785 - Galactose-binding domain-like
  • 0.00005649Direct
    49785,49785,49899
  • 49785 - Galactose-binding domain-like
  • 49785 - Galactose-binding domain-like
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.00005649Direct
    48097,56112,50729
  • 48097 - Regulator of G-protein signaling, RGS
  • 56112 - Protein kinase-like (PK-like)
  • 50729 - PH domain-like
  • 0.0000695Direct
    49854,49854,49785
  • 49854 - Spermadhesin, CUB domain
  • 49854 - Spermadhesin, CUB domain
  • 49785 - Galactose-binding domain-like
  • 0.00007209Direct
    54001,49758,47473
  • 54001 - Cysteine proteinases
  • 49758 - Calpain large subunit, middle domain (domain III)
  • 47473 - EF-hand
  • 0.00007209Direct
    47031,50729,56112
  • 47031 - Second domain of FERM
  • 50729 - PH domain-like
  • 56112 - Protein kinase-like (PK-like)
  • 0.0001069Direct
    46966,46966,50729
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 50729 - PH domain-like
  • 0.0001069Direct
    49562,48371,56112
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 48371 - ARM repeat
  • 56112 - Protein kinase-like (PK-like)
  • 0.000127Direct
    49265,49265,49265
  • 49265 - Fibronectin type III
  • 49265 - Fibronectin type III
  • 49265 - Fibronectin type III
  • 0.0001409Direct
    47220,47220,109885
  • 47220 - alpha-catenin/vinculin-like
  • 47220 - alpha-catenin/vinculin-like
  • 109885 - I/LWEQ domain
  • 0.0001577Direct
    57196,57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.0001606Direct
    57196,63825,57196
  • 57196 - EGF/Laminin
  • 63825 - YWTD domain
  • 57196 - EGF/Laminin
  • 0.0001725Direct
    81296,81296,81296
  • 81296 - E set domains
  • 81296 - E set domains
  • 81296 - E set domains
  • 0.0001774Direct
    101288,101288,50156
  • 101288 - L27 domain
  • 101288 - L27 domain
  • 50156 - PDZ domain-like
  • 0.0001933Direct
    57889,49562,56112
  • 57889 - Cysteine-rich domain
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 56112 - Protein kinase-like (PK-like)
  • 0.0002355Direct
    55753,55753,55753
  • 55753 - Actin depolymerizing proteins
  • 55753 - Actin depolymerizing proteins
  • 55753 - Actin depolymerizing proteins
  • 0.000288Direct
    103473,103473,141571
  • 103473 - MFS general substrate transporter
  • 103473 - MFS general substrate transporter
  • 141571 - Pentapeptide repeat-like
  • 0.0003261Direct
    64268,50729,56024
  • 64268 - PX domain
  • 50729 - PH domain-like
  • 56024 - Phospholipase D/nuclease
  • 0.0003261Direct
    54768,54768,54768
  • 54768 - dsRNA-binding domain-like
  • 54768 - dsRNA-binding domain-like
  • 54768 - dsRNA-binding domain-like
  • 0.0003281Direct
    55550,50044,51695
  • 55550 - SH2 domain
  • 50044 - SH3-domain
  • 51695 - PLC-like phosphodiesterases
  • 0.0004181Direct
    55008,55008,55008
  • 55008 - HMA, heavy metal-associated domain
  • 55008 - HMA, heavy metal-associated domain
  • 55008 - HMA, heavy metal-associated domain
  • 0.0005124Direct
    46585,46585,46585
  • 46585 - HR1 repeat
  • 46585 - HR1 repeat
  • 46585 - HR1 repeat
  • 0.0005124Direct
    50044,51695,49562
  • 50044 - SH3-domain
  • 51695 - PLC-like phosphodiesterases
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 0.0007166Direct
    57716,57716,50156
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 50156 - PDZ domain-like
  • 0.0007602Direct
    81660,56784,81665
  • 81660 - Metal cation-transporting ATPase, ATP-binding domain N
  • 56784 - HAD-like
  • 81665 - Calcium ATPase, transmembrane domain M
  • 0.0008269Direct
    49899,57196,57196
  • 49899 - Concanavalin A-like lectins/glucanases
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.004656Inherited
    55781,55781,109604
  • 55781 - GAF domain-like
  • 55781 - GAF domain-like
  • 109604 - HD-domain/PDEase-like
  • 0.004533Inherited
    57535,57535,57535
  • 57535 - Complement control module/SCR domain
  • 57535 - Complement control module/SCR domain
  • 57535 - Complement control module/SCR domain
  • 0.3962Inherited
    57667,57667,57667
  • 57667 - beta-beta-alpha zinc fingers
  • 57667 - beta-beta-alpha zinc fingers
  • 57667 - beta-beta-alpha zinc fingers
  • 1Inherited
    53822,53850,81324
  • 53822 - Periplasmic binding protein-like I
  • 53850 - Periplasmic binding protein-like II
  • 81324 - Voltage-gated potassium channels
  • 0.002565Inherited
    57903,47370,63748
  • 57903 - FYVE/PHD zinc finger
  • 47370 - Bromodomain
  • 63748 - Tudor/PWWP/MBT
  • 0.001079Inherited
    49562,49562,53300
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 53300 - vWA-like
  • 0.001672Inherited
    48726,48726,82895
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 82895 - TSP-1 type 1 repeat
  • 0.02514Inherited
    48726,48726,48726
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 0.1367Inherited
    57424,57424,57196
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 57196 - EGF/Laminin
  • 0.01157Inherited
    57196,57196,63825
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 63825 - YWTD domain
  • 0.01358Inherited
    57424,57196,57196
  • 57424 - LDL receptor-like module
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.01769Inherited
    57424,57424,57424
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 0.03Inherited
    90123,52540,90123
  • 90123 - ABC transporter transmembrane region
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 90123 - ABC transporter transmembrane region
  • 0.3756Inherited
    52540,90123,52540
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 90123 - ABC transporter transmembrane region
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.3907Inherited
    57196,49854,49854
  • 57196 - EGF/Laminin
  • 49854 - Spermadhesin, CUB domain
  • 49854 - Spermadhesin, CUB domain
  • 0.001727Inherited
    48726,48726,49265
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 0.1136Inherited
    48092,47655,49417
  • 48092 - Transcription factor STAT-4 N-domain
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 0.003294Inherited
    47655,49417,55550
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 55550 - SH2 domain
  • 0.00447Inherited
    47090,55486,50923
  • 47090 - PGBD-like
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 50923 - Hemopexin-like domain
  • 0.003849Inherited
    51045,51045,50156
  • 51045 - WW domain
  • 51045 - WW domain
  • 50156 - PDZ domain-like
  • 0.004087Inherited
    50156,52540,51045
  • 50156 - PDZ domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 51045 - WW domain
  • 1Inherited
    47769,47769,47769
  • 47769 - SAM/Pointed domain
  • 47769 - SAM/Pointed domain
  • 47769 - SAM/Pointed domain
  • 0.001939Inherited
    63882,53218,63867
  • 63882 - MoeA N-terminal region -like
  • 53218 - Molybdenum cofactor biosynthesis proteins
  • 63867 - MoeA C-terminal domain-like
  • 0.01157Inherited
    52540,51045,51045
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 51045 - WW domain
  • 51045 - WW domain
  • 1Inherited
    52058,48726,48726
  • 52058 - L domain-like
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 0.03157Inherited
    57196,57184,57196
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 0.002775Inherited
    54791,54791,54791
  • 54791 - Eukaryotic type KH-domain (KH-domain type I)
  • 54791 - Eukaryotic type KH-domain (KH-domain type I)
  • 54791 - Eukaryotic type KH-domain (KH-domain type I)
  • 0.02391Inherited
    90257,90257,90257
  • 90257 - Myosin rod fragments
  • 90257 - Myosin rod fragments
  • 90257 - Myosin rod fragments
  • 0.001529Inherited
    55550,55550,50044
  • 55550 - SH2 domain
  • 55550 - SH2 domain
  • 50044 - SH3-domain
  • 0.00141Inherited
    109880,109885,109885
  • 109880 - A middle domain of Talin 1
  • 109885 - I/LWEQ domain
  • 109885 - I/LWEQ domain
  • 0.006097Inherited
    50729,57903,50729
  • 50729 - PH domain-like
  • 57903 - FYVE/PHD zinc finger
  • 50729 - PH domain-like
  • 1Inherited
    48065,50729,57903
  • 48065 - DBL homology domain (DH-domain)
  • 50729 - PH domain-like
  • 57903 - FYVE/PHD zinc finger
  • 1Inherited


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