SUPERFAMILY 1.75 HMM library and genome assignments server

Superfamily is undergoing a server migration - you are now browsing on the new server. Please contact us if you experience any problems.

Biological Process (BP): regulation of multicellular organismal development

(show info)

Jump to [ Top · GO Hierarchy · Superfamily · Family · Supra-domain ]

Root: GO Hierarchy Containing Three Sub-Ontologies (BP, MF, CC)

Shortest distance to current term (+ for parents, - for children) GO term [GO ID] <#Children> #High-quality
(SF|FA)
#Supra-domain
(Single|Duplex|Triple)
+ + + + 4:   biological_process [GO:0008150] <24>
+ + + 3:   biological regulation [GO:0065007] <5>(165|190) (757|933|542)
+ + 2:   regulation of biological process [GO:0050789] <34>(155|176) (709|883|505)
+ 1:   regulation of developmental process [GO:0050793] <28>(34|33) (298|322|199)
+ 1:   regulation of multicellular organismal process [GO:0051239] <48>(40|41) (340|360|224)
0:   regulation of multicellular organismal development [GO:2000026] <72>(28|28) (253|276|169)
- 1:   regulation of organ morphogenesis [GO:2000027] <47>(2|2) (63|42|21)
- 1:   regulation of embryonic development [GO:0045995] <29>(1|1) (42|17|4)
- 1:   regulation of epithelial cell differentiation [GO:0030856] <19>(2|2) (32|18|7)
- 1:   regulation of post-embryonic development [GO:0048580] <17>(2|2) (44|20|7)
- 1:   regulation of nervous system development [GO:0051960] <13>(11|8) (152|178|103)
- 1:   regulation of kidney development [GO:0090183] <11>(0|0) (19|7|2)
- 1:   regulation of spore-bearing organ development [GO:0075260] <11>(0|0) (0|0|0)
- 1:   regulation of tolerance induction [GO:0002643] <10>(0|0) (4|1|0)
- 1:   regulation of vasculature development [GO:1901342] <10>(9|9) (71|62|43)
- 1:   regulation of cardiocyte differentiation [GO:1905207] <8>(0|0) (4|0|0)
- 1:   regulation of hemopoiesis [GO:1903706] <7>(5|5) (72|49|30)
- 1:   regulation of bone development [GO:1903010] <6>(0|0) (1|2|1)
- 1:   regulation of isotype switching [GO:0045191] <6>(1|1) (10|4|2)
- 1:   regulation of biomineral tissue development [GO:0070167] <5>(0|0) (15|21|15)
- 1:   regulation of cartilage development [GO:0061035] <5>(0|0) (14|5|5)
- 1:   regulation of epithelial to mesenchymal transition [GO:0010717] <5>(0|0) (11|6|6)
- 1:   regulation of muscle organ development [GO:0048634] <5>(1|1) (25|17|11)
- 1:   regulation of neural crest cell differentiation [GO:1905292] <5>(0|0) (0|0|0)
- 1:   regulation of shoot system development [GO:0048831] <5>(1|1) (9|5|1)
- 1:   regulation of Wnt signaling pathway involved in heart development [GO:0003307] <4>(0|0) (2|0|0)
- 1:   regulation of cardiac ventricle development [GO:1904412] <4>(0|0) (0|0|0)
- 1:   regulation of epithelial tube formation [GO:1905276] <4>(0|0) (9|4|1)
- 1:   regulation of gonad development [GO:1905939] <4>(1|1) (8|2|1)
- 1:   regulation of hair follicle development [GO:0051797] <4>(0|0) (1|0|0)
- 1:   regulation of chitin-based cuticle tanning [GO:0007564] <3>(1|1) (3|1|0)
- 1:   regulation of cuticle pigmentation [GO:0048079] <3>(1|1) (8|5|3)
- 1:   regulation of heart growth [GO:0060420] <3>(1|1) (6|4|3)
- 1:   regulation of mammary gland epithelial cell proliferation [GO:0033599] <3>(0|0) (6|0|0)
- 1:   regulation of retina development in camera-type eye [GO:1902866] <3>(0|0) (5|2|0)
- 1:   regulation of root development [GO:2000280] <3>(0|0) (4|1|0)
- 1:   regulation of skeletal muscle tissue regeneration [GO:0043416] <3>(0|0) (4|1|0)
- 1:   regulation of BMP signaling pathway involved in determination of lateral mesoderm left/right asymmet [GO:1902812] <2>(0|0) (0|0|0)
- 1:   regulation of Wnt signaling pathway involved in dorsal/ventral axis specification [GO:2000053] <2>(0|0) (0|0|0)
- 1:   regulation of adipose tissue development [GO:1904177] <2>(0|0) (2|0|0)
- 1:   regulation of antipodal cell differentiation [GO:0045688] <2>(0|0) (0|0|0)
- 1:   regulation of apical ectodermal ridge formation [GO:1905140] <2>(0|0) (0|0|0)
- 1:   regulation of determination of dorsal identity [GO:2000015] <2>(0|0) (0|0|0)
- 1:   regulation of eclosion [GO:0007563] <2>(0|0) (1|1|1)
- 1:   regulation of embryo sac central cell differentiation [GO:0045691] <2>(0|0) (0|0|0)
- 1:   regulation of embryo sac egg cell differentiation [GO:0045694] <2>(0|0) (0|0|0)
- 1:   regulation of endothelial tube morphogenesis [GO:1901509] <2>(1|1) (1|0|0)
- 1:   regulation of epithelial cell proliferation involved in prostate gland development [GO:0060768] <2>(0|0) (1|0|0)
- 1:   regulation of female pigmentation [GO:0048089] <2>(0|0) (0|0|0)
- 1:   regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/ [GO:2000313] <2>(0|0) (0|0|0)
- 1:   regulation of imaginal disc growth [GO:0045570] <2>(0|0) (1|2|1)
- 1:   regulation of insulin receptor signaling pathway involved in determination of adult lifespan [GO:1903104] <2>(0|0) (0|0|0)
- 1:   regulation of lactation [GO:1903487] <2>(0|1) (3|0|0)
- 1:   regulation of lens epithelial cell proliferation [GO:2001109] <2>(0|0) (2|0|0)
- 1:   regulation of lung alveolus development [GO:1904653] <2>(0|0) (0|0|0)
- 1:   regulation of male pigmentation [GO:0048088] <2>(0|0) (0|0|0)
- 1:   regulation of mammary stem cell proliferation [GO:2000101] <2>(0|0) (0|0|0)
- 1:   regulation of mesenchymal cell proliferation involved in lung development [GO:2000790] <2>(0|0) (0|0|0)
- 1:   regulation of mesenchymal cell proliferation involved in ureter development [GO:0072199] <2>(0|0) (3|1|0)
- 1:   regulation of nematode male tail tip morphogenesis [GO:0110037] <2>(0|0) (0|0|0)
- 1:   regulation of nodal signaling pathway involved in determination of left/right asymmetry [GO:1900145] <2>(0|0) (1|0|0)
- 1:   regulation of plant organ morphogenesis [GO:1905421] <2>(0|0) (0|0|0)
- 1:   regulation of synergid differentiation [GO:0045697] <2>(0|0) (0|0|0)
- 1:   regulation of thyroid gland epithelial cell proliferation [GO:1904441] <2>(0|0) (0|0|0)
- 1:   regulation of trophoblast cell migration [GO:1901163] <2>(0|0) (1|0|0)
- 1:   regulation of Wnt signaling pathway involved in digestive tract morphogenesis [GO:2000056] <1>(0|0) (2|1|0)
- 1:   regulation of trichome patterning [GO:1900032] <1>(0|0) (1|0|0)
- 1:   regulation of tube lumen cavitation [GO:1903132] <1>(0|0) (0|0|0)
- 1:   negative regulation of fusion cell fate specification [GO:0035157](0|0) (2|2|1)
- 1:   negative regulation of mammary gland development in males by androgen receptor signaling pathway [GO:0060614](0|0) (0|0|0)
- 1:   negative regulation of terminal cell fate specification, open tracheal system [GO:0035155](0|0) (0|0|0)
- 1:   regulation of adaxial/abaxial pattern formation [GO:2000011](0|0) (3|2|1)
- 1:   regulation of epithelial cell migration, open tracheal system [GO:2000274](0|0) (3|2|2)
- 1:   regulation of mesenchymal cell proliferation involved in prostate gland development [GO:0060782](0|0) (0|0|0)
- 1:   regulation of metaxylem development [GO:0090060](0|0) (0|0|0)
- 1:   regulation of radial pattern formation [GO:0090213](0|0) (0|0|0)
- 1:   regulation of stomatal complex patterning [GO:2000037](0|0) (0|0|0)
- 1:   regulation of transforming growth factor receptor beta signaling pathway involved in determination o [GO:0035464](0|0) (0|0|0)


Jump to [ Top · GO Hierarchy · Superfamily · Family · Supra-domain ]

Superfamily

(show details)
SCOP termFDR (singleton)FDR (all)Annotation (direct or inherited)
Immunoglobulin0.00028990.00000488Direct
Nucleoside diphosphate kinase, NDK0.0000000022460.0009568Direct
Ankyrin repeat0.3820.3722Inherited
Family A G protein-coupled receptor-like11Inherited
Annexin0.059470.5698Inherited
N-terminal nucleophile aminohydrolases (Ntn hydrolases)0.057431Inherited
Interleukin 8-like chemokines0.0059630.5015Inherited
Insulin-like0.14371Inherited
Protein kinase-like (PK-like)0.5790.002674Inherited
HLH, helix-loop-helix DNA-binding domain0.028750Inherited
Stathmin0.0000016520.001226Inherited
Caspase-like0.0083160.5945Inherited
Formate/glycerate dehydrogenase catalytic domain-like0.00000040810.008281Inherited
Cysteine proteinases0.00024670.03699Inherited
Cytokine0.0031680.1414Inherited
4-helical cytokines0.011580.06061Inherited
(Trans)glycosidases0.00069071Inherited
Aquaporin-like0.0047730.8441Inherited
Cytochrome P4500.00028991Inherited
Inhibitor of apoptosis (IAP) repeat0.076111Inherited
Metallothionein0.00000019030.001055Inherited
Actin depolymerizing proteins0.7210.7761Inherited
C-type lectin-like0.014481Inherited
Trypsin-like serine proteases0.79151Inherited
EF-hand10.7155Inherited
Serpins0.0071030.4752Inherited
P-loop containing nucleoside triphosphate hydrolases0.34791Inherited
PEBP-like0.25060.4852Inherited


Jump to [ Top · GO Hierarchy · Superfamily · Family · Supra-domain ]

Family

(show details)
SCOP termFDR (singleton)FDR (all)Annotation (direct or inherited)
Fibroblast growth factors (FGF)00.0003633Direct
Formate/glycerate dehydrogenases, substrate-binding domain0.0000005840.0003954Direct
Long-chain cytokines0.0000001480.0003957Direct
Short-chain cytokines0.00034470.0001922Direct
Ankyrin repeat0.35910.4857Inherited
Rhodopsin-like11Inherited
Annexin0.05520.5535Inherited
Proteasome subunits0.034831Inherited
Interleukin 8-like chemokines0.0056190.5084Inherited
Insulin-like0.13260.9834Inherited
Protein kinases, catalytic subunit0.54860.006838Inherited
HLH, helix-loop-helix DNA-binding domain0.02660Inherited
Stathmin0.0000030970.002054Inherited
Caspase catalytic domain0.0074820.4658Inherited
Aquaporin-like0.0075170.9297Inherited
Bee venom hyaluronidase01Inherited
Cytochrome P4500.00026081Inherited
Inhibitor of apoptosis (IAP) repeat0.06941Inherited
Papain-like0.000027320.001756Inherited
Nucleoside diphosphate kinase, NDK0.0000000089750.002504Inherited
Metallothionein0.00000071860.002748Inherited
Cofilin-like0.68310.6366Inherited
Calmodulin-like0.84131Inherited
C-type lectin domain0.013081Inherited
Eukaryotic proteases0.67030.9256Inherited
Serpins0.006480.4658Inherited
Phosphatidylethanolamine binding protein0.23380.4659Inherited
G proteins0.28291Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this GO term
Plot tree as:   Download Newick format tree:
(show help)

Jump to [ Top · GO Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

(show details)
Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Cystine-knot cytokines0Direct
HLH, helix-loop-helix DNA-binding domain0Direct
Snake toxin-like0Direct
Heparin-binding domain from vascular endothelial growth factor0Direct
Homeodomain-like0.000000000000005554Direct
PDZ domain-like0.00000000000004467Direct
Fibronectin type III0.0000000000002971Direct
HMG-box0.0000000001851Direct
Hedgehog/DD-peptidase0.00000000177Direct
EGF/Laminin0.000000002425Direct
Hairpin loop containing domain-like0.000000003623Direct
Hedgehog/intein (Hint) domain0.00000006292Direct
SAM/Pointed domain0.0000004766Direct
Transferrin receptor-like dimerisation domain0.0000005351Direct
Growth factor receptor domain0.0000006014Direct
GAS2 domain-like0.000000767Direct
Concanavalin A-like lectins/glucanases0.000002933Direct
Immunoglobulin0.000003192Direct
DNA-binding protein LAG-1 (CSL)0.000004111Direct
Zn-finger domain of Sec23/240.00002373Direct
Transcription factor STAT-4 N-domain0.00005291Direct
p53-like transcription factors0.00005336Direct
Calpain large subunit, middle domain (domain III)0.00005722Direct
Orange domain-like0.00008738Direct
STAT0.0001124Direct
CCCH zinc finger0.0002025Direct
Frizzled cysteine-rich domain0.0002162Direct
GTPase activation domain, GAP0.0002179Direct
Galactose-binding domain-like0.0002874Direct
TIMP-like0.000429Direct
HIT/MYND zinc finger-like0.0005499Direct
Ras GEF0.0006553Direct
Nucleoside diphosphate kinase, NDK0.0006804Direct
Metallothionein0.0007518Direct
Cadherin-like0.0007835Direct
Stathmin0.0008767Direct
Glucocorticoid receptor-like (DNA-binding domain)1Inherited
TNF-like0.6123Inherited
Ribonuclease H-like1Inherited
PH domain-like0.8709Inherited
DBL homology domain (DH-domain)0.2634Inherited
TPR-like1Inherited
G protein-binding domain0.005334Inherited
CheY-like1Inherited
Tetraspanin1Inherited
NAC domain0.03831Inherited
ENTH/VHS domain0.2553Inherited
MFS general substrate transporter1Inherited
ARM repeat0.1265Inherited
Pseudo ankyrin repeat-like0.1494Inherited
PAZ domain0.858Inherited
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases0.9287Inherited
Pectin lyase-like1Inherited
Leucine zipper domain1Inherited
Myosin S1 fragment, N-terminal domain0.4119Inherited
RING/U-box0.8499Inherited
Tropomyosin0.8162Inherited
4-helical cytokines0.04728Inherited
Annexin0.4884Inherited
Metalloproteases ("zincins"), catalytic domain0.9041Inherited
PGBD-like0.1138Inherited
Hemopexin-like domain0.5126Inherited
SH2 domain0.002054Inherited
DEATH domain1Inherited
Cysteine-rich domain0.6779Inherited
GLA-domain1Inherited
MHC antigen-recognition domain1Inherited
N-acetylmuramoyl-L-alanine amidase-like0.954Inherited
Periplasmic binding protein-like II1Inherited
A DNA-binding domain in eukaryotic transcription factors0.03729Inherited
POZ domain1Inherited
dsRNA-binding domain-like0.5254Inherited
Actin-like ATPase domain1Inherited
FAS1 domain0.3273Inherited
C-type lectin-like1Inherited
DNA-binding pseudobarrel domain0.001079Inherited
FnI-like domain0.2989Inherited
Class II aaRS and biotin synthetases0.5541Inherited
Cystatin/monellin0.2042Inherited
Alkaline phosphatase-like0.007326Inherited
tRNA-binding arm0.001007Inherited
TSP type-3 repeat0.1379Inherited
PLC-like phosphodiesterases0.7128Inherited
Mitochondrial glycoprotein MAM33-like0.001982Inherited
Homodimeric domain of signal transducing histidine kinase0.9827Inherited
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase1Inherited
Calcium-dependent phosphotriesterase0.6398Inherited
Thyroglobulin type-1 domain0.1999Inherited
NTF2-like1Inherited
Plexin repeat1Inherited
Integrin domains0.9251Inherited
L domain-like0.002001Inherited
Eukaryotic type KH-domain (KH-domain type I)0.4202Inherited
SOCS box-like0.008058Inherited
Fibrinogen C-terminal domain-like0.8498Inherited
DHS-like NAD/FAD-binding domain0.1973Inherited
Carbonic anhydrase0.2505Inherited
Second domain of FERM0.9409Inherited
Somatomedin B domain0.673Inherited
RNA-binding domain, RBD1Inherited
Ran binding protein zinc finger-like1Inherited
Thioredoxin-like1Inherited
lambda repressor-like DNA-binding domains0.1125Inherited
Insulin-like0.9251Inherited
SMAD/FHA domain0.003704Inherited
SMAD MH1 domain0.001631Inherited
N-terminal domain of cbl (N-cbl)0.001174Inherited
E2F-DP heterodimerization region0.9461Inherited
Chromo domain-like0.2522Inherited
Nuclear receptor ligand-binding domain1Inherited
Actin depolymerizing proteins0.6807Inherited
alpha/beta-Hydrolases1Inherited
Cyclin-like0.9879Inherited
Bromodomain0.6807Inherited
Rap/Ran-GAP0.4578Inherited
Subdomain of clathrin and coatomer appendage domain0.1175Inherited
N-terminal nucleophile aminohydrolases (Ntn hydrolases)1Inherited
Clathrin adaptor appendage domain0.5012Inherited
WW domain0.09343Inherited
SRF-like0.7184Inherited
Toll/Interleukin receptor TIR domain1Inherited
SEA domain0.8862Inherited
Subtilisin-like1Inherited
Protease propeptides/inhibitors0.9287Inherited
FAT domain of focal adhesion kinase0.01774Inherited
YWTD domain0.01076Inherited
HR1 repeat0.02613Inherited
F-box domain0.7607Inherited
LDL receptor-like module0.05029Inherited
cAMP-binding domain-like1Inherited
Quinoprotein alcohol dehydrogenase-like0.7213Inherited
TSP-1 type 1 repeat0.249Inherited
FAD/NAD(P)-binding domain1Inherited
Serpins0.403Inherited
vWA-like0.9335Inherited
Arginase/deacetylase0.001554Inherited
C-terminal, gelsolin-like domain of Sec23/240.0714Inherited
Midkine0.006544Inherited
Helical domain of Sec23/240.001079Inherited
FF domain0.327Inherited
FYVE/PHD zinc finger0.5496Inherited
Cupredoxins1Inherited
Metallo-dependent hydrolases0.8649Inherited
Composite domain of metallo-dependent hydrolases0.03298Inherited
Kazal-type serine protease inhibitors0.1999Inherited
TAFH domain-like0.0786Inherited
Formate/glycerate dehydrogenase catalytic domain-like0.00612Inherited
S-adenosyl-L-methionine-dependent methyltransferases1Inherited
Notch domain0.00217Inherited
BAR/IMD domain-like0.0454Inherited
Ubiquitin-like0.2947Inherited
Caspase-like0.511Inherited
PYP-like sensor domain (PAS domain)0.9555Inherited
SAP domain0.9448Inherited
Kringle-like0.01756Inherited
Soluble quinoprotein glucose dehydrogenase0.0786Inherited
Connexin430.9461Inherited
Multidrug efflux transporter AcrB transmembrane domain0.1099Inherited
Histone-fold0.8868Inherited
Clavaminate synthase-like1Inherited
PEBP-like0.4119Inherited
JAB1/MPN domain0.4546Inherited
DNA-binding domain1Inherited
Ankyrin repeat0.3115Inherited
Cysteine proteinases0.02843Inherited
SRCR-like0.07326Inherited
CAD & PB1 domains0.02603Inherited
TRAF domain-like0.5645Inherited
CRAL/TRIO domain0.02996Inherited
Tudor/PWWP/MBT0.4238Inherited
PA domain0.2029Inherited
Zn-dependent exopeptidases0.8534Inherited
BRCT domain0.04556Inherited
Interleukin 8-like chemokines0.4266Inherited
Spermadhesin, CUB domain0.0762Inherited
Kelch motif0.1658Inherited
Plakin repeat0.001413Inherited
Spectrin repeat0.2183Inherited
Calponin-homology domain, CH-domain0.8407Inherited
EF-hand0.6234Inherited
RUN domain-like0.187Inherited
Integrin beta tail domain1Inherited
ThrRS/AlaRS common domain0.07804Inherited
TGS-like0.2049Inherited
Class II aaRS ABD-related0.9158Inherited
ValRS/IleRS/LeuRS editing domain0.4938Inherited
Family A G protein-coupled receptor-like1Inherited
Serine protease inhibitors0.2183Inherited
Serum albumin-like0.1918Inherited
Complement control module/SCR domain0.1511Inherited
Chitinase insertion domain0.01277Inherited
Aquaporin-like0.7463Inherited
Inhibitor of apoptosis (IAP) repeat1Inherited
Cytochrome P4501Inherited
(Trans)glycosidases1Inherited
Lipoxigenase0.6169Inherited
beta-beta-alpha zinc fingers0.0386Inherited
NHL repeat0.0109Inherited
Carboxypeptidase regulatory domain-like0.02053Inherited
RNase III domain-like0.1233Inherited
Protein serine/threonine phosphatase 2C, C-terminal domain0.8412Inherited
PP2C-like1Inherited
TB module/8-cys domain0.4578Inherited
FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP)0.02053Inherited
beta-sandwich domain of Sec23/240.04556Inherited
Cullin homology domain0.002422Inherited
CAPPD, an extracellular domain of amyloid beta A4 protein0.5616Inherited
A heparin-binding domain0.6377Inherited
Amyloid beta a4 protein copper binding domain (domain 2)0.9193Inherited
Hect, E3 ligase catalytic domain0.06315Inherited
C2 domain (Calcium/lipid-binding domain, CaLB)0.6232Inherited
(Phosphotyrosine protein) phosphatases II0.4315Inherited
HCP-like0.9782Inherited
SPOC domain-like0.1507Inherited
Heat shock protein 70kD (HSP70), peptide-binding domain0.5839Inherited
Pentein0.1757Inherited
SET domain0.01934Inherited
14-3-3 protein0.04815Inherited
Trypsin-like serine proteases1Inherited
BTG domain-like0.1663Inherited
RNI-like1Inherited
Cytokine0.1134Inherited
TNF receptor-like0.7684Inherited
Restriction endonuclease-like0.9205Inherited
SAND domain-like0.0714Inherited
RGC domain-like0.1227Inherited
Intermediate filament protein, coiled coil region0.8237Inherited
KA1-like1Inherited
SH3-domain0.4943Inherited
Protein kinase-like (PK-like)0.001938Inherited
WD40 repeat-like1Inherited
Sema domain0.9149Inherited
E set domains1Inherited
Regulator of G-protein signaling, RGS1Inherited
P-loop containing nucleoside triphosphate hydrolases1Inherited
FKBP-like0.7306Inherited
Sialidases0.3964Inherited
Apolipoprotein A-I0.772Inherited
Blood coagulation inhibitor (disintegrin)0.8964Inherited
TATA-box binding protein-like0.2322Inherited
YVTN repeat-like/Quinoprotein amine dehydrogenase0.006299Inherited
occludin/ELL-like0.02783Inherited
SBT domain0.7301Inherited
Chaperone J-domain1Inherited
Rhodanese/Cell cycle control phosphatase0.6135Inherited
BRK domain-like0.0131Inherited
L27 domain0.003407Inherited
SAICAR synthase-like0.2766Inherited
Cullin repeat-like0.2858Inherited
ACP-like1Inherited
Acetyl-CoA synthetase-like1Inherited
eIF4e-like0.4893Inherited
"Winged helix" DNA-binding domain0.7085Inherited

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
57196,49899
  • 57196 - EGF/Laminin
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0Direct
    48097,57889
  • 48097 - Regulator of G-protein signaling, RGS
  • 57889 - Cysteine-rich domain
  • 0Direct
    103652,50729
  • 103652 - G protein-binding domain
  • 50729 - PH domain-like
  • 0Direct
    56491,109843
  • 56491 - A heparin-binding domain
  • 109843 - CAPPD, an extracellular domain of amyloid beta A4 protein
  • 0Direct
    48726,49265
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 0Direct
    47473,57997
  • 47473 - EF-hand
  • 57997 - Tropomyosin
  • 0Direct
    52058,48726
  • 52058 - L domain-like
  • 48726 - Immunoglobulin
  • 0Direct
    48371,48350
  • 48371 - ARM repeat
  • 48350 - GTPase activation domain, GAP
  • 0Direct
    48371,52087
  • 48371 - ARM repeat
  • 52087 - CRAL/TRIO domain
  • 0Direct
    48350,48371
  • 48350 - GTPase activation domain, GAP
  • 48371 - ARM repeat
  • 0Direct
    51695,55550
  • 51695 - PLC-like phosphodiesterases
  • 55550 - SH2 domain
  • 0Direct
    81383,49899
  • 81383 - F-box domain
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0Direct
    57501,57593
  • 57501 - Cystine-knot cytokines
  • 57593 - Heparin-binding domain from vascular endothelial growth factor
  • 0Direct
    63763,47095
  • 63763 - SAND domain-like
  • 47095 - HMG-box
  • 0Direct
    49899,57196
  • 49899 - Concanavalin A-like lectins/glucanases
  • 57196 - EGF/Laminin
  • 0Direct
    75399,46966
  • 75399 - Plakin repeat
  • 46966 - Spectrin repeat
  • 0Direct
    56112,47769
  • 56112 - Protein kinase-like (PK-like)
  • 47769 - SAM/Pointed domain
  • 0Direct
    57184,82153
  • 57184 - Growth factor receptor domain
  • 82153 - FAS1 domain
  • 0Direct
    49854,117281
  • 49854 - Spermadhesin, CUB domain
  • 117281 - Kelch motif
  • 0Direct
    49758,47473
  • 49758 - Calpain large subunit, middle domain (domain III)
  • 47473 - EF-hand
  • 0.000000000000001898Direct
    49899,48726
  • 49899 - Concanavalin A-like lectins/glucanases
  • 48726 - Immunoglobulin
  • 0.00000000000006739Direct
    54277,57889
  • 54277 - CAD & PB1 domains
  • 57889 - Cysteine-rich domain
  • 0.000000000000374Direct
    55166,51294
  • 55166 - Hedgehog/DD-peptidase
  • 51294 - Hedgehog/intein (Hint) domain
  • 0.000000000002349Direct
    54236,48366
  • 54236 - Ubiquitin-like
  • 48366 - Ras GEF
  • 0.000000000002407Direct
    57184,49265
  • 57184 - Growth factor receptor domain
  • 49265 - Fibronectin type III
  • 0.000000000002801Direct
    47576,46966
  • 47576 - Calponin-homology domain, CH-domain
  • 46966 - Spectrin repeat
  • 0.00000000002595Direct
    82895,57196
  • 82895 - TSP-1 type 1 repeat
  • 57196 - EGF/Laminin
  • 0.0000000001274Direct
    103575,48726
  • 103575 - Plexin repeat
  • 48726 - Immunoglobulin
  • 0.0000000001757Direct
    54495,54211
  • 54495 - UBC-like
  • 54211 - Ribosomal protein S5 domain 2-like
  • 0.000000001365Direct
    54236,49879
  • 54236 - Ubiquitin-like
  • 49879 - SMAD/FHA domain
  • 0.000000001393Direct
    47095,47095
  • 47095 - HMG-box
  • 47095 - HMG-box
  • 0.000000001428Direct
    47576,143575
  • 47576 - Calponin-homology domain, CH-domain
  • 143575 - GAS2 domain-like
  • 0.000000001603Direct
    57414,57440
  • 57414 - Hairpin loop containing domain-like
  • 57440 - Kringle-like
  • 0.0000000585Direct
    57196,57184
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 0.00000006569Direct
    49265,48726
  • 49265 - Fibronectin type III
  • 48726 - Immunoglobulin
  • 0.0000001082Direct
    48371,49785
  • 48371 - ARM repeat
  • 49785 - Galactose-binding domain-like
  • 0.0000005007Direct
    48403,47031
  • 48403 - Ankyrin repeat
  • 47031 - Second domain of FERM
  • 0.0000005007Direct
    53187,47672
  • 53187 - Zn-dependent exopeptidases
  • 47672 - Transferrin receptor-like dimerisation domain
  • 0.0000005351Direct
    50044,50156
  • 50044 - SH3-domain
  • 50156 - PDZ domain-like
  • 0.0000005821Direct
    50156,50156
  • 50156 - PDZ domain-like
  • 50156 - PDZ domain-like
  • 0.0000007284Direct
    48726,82895
  • 48726 - Immunoglobulin
  • 82895 - TSP-1 type 1 repeat
  • 0.0000008998Direct
    49313,49899
  • 49313 - Cadherin-like
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.000001079Direct
    110217,81296
  • 110217 - DNA-binding protein LAG-1 (CSL)
  • 81296 - E set domains
  • 0.000001079Direct
    57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.00000195Direct
    49899,49899
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.000002428Direct
    63748,48371
  • 63748 - Tudor/PWWP/MBT
  • 48371 - ARM repeat
  • 0.00000261Direct
    52172,46689
  • 52172 - CheY-like
  • 46689 - Homeodomain-like
  • 0.000002714Direct
    52058,57196
  • 52058 - L domain-like
  • 57196 - EGF/Laminin
  • 0.000003401Direct
    49417,110217
  • 49417 - p53-like transcription factors
  • 110217 - DNA-binding protein LAG-1 (CSL)
  • 0.000004111Direct
    47769,47769
  • 47769 - SAM/Pointed domain
  • 47769 - SAM/Pointed domain
  • 0.000006261Direct
    52025,53187
  • 52025 - PA domain
  • 53187 - Zn-dependent exopeptidases
  • 0.000008854Direct
    56112,50998
  • 56112 - Protein kinase-like (PK-like)
  • 50998 - Quinoprotein alcohol dehydrogenase-like
  • 0.000009783Direct
    48350,50044
  • 48350 - GTPase activation domain, GAP
  • 50044 - SH3-domain
  • 0.000009887Direct
    50156,50044
  • 50156 - PDZ domain-like
  • 50044 - SH3-domain
  • 0.00001461Direct
    48726,48726
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 0.00001463Direct
    50044,50729
  • 50044 - SH3-domain
  • 50729 - PH domain-like
  • 0.00001984Direct
    57440,56112
  • 57440 - Kringle-like
  • 56112 - Protein kinase-like (PK-like)
  • 0.00001984Direct
    53649,53649
  • 53649 - Alkaline phosphatase-like
  • 53649 - Alkaline phosphatase-like
  • 0.00002312Direct
    82919,53300
  • 82919 - Zn-finger domain of Sec23/24
  • 53300 - vWA-like
  • 0.00002373Direct
    52799,52799
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 0.00002736Direct
    57196,100895
  • 57196 - EGF/Laminin
  • 100895 - Kazal-type serine protease inhibitors
  • 0.00003583Direct
    49562,51045
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 51045 - WW domain
  • 0.00003583Direct
    50242,100895
  • 50242 - TIMP-like
  • 100895 - Kazal-type serine protease inhibitors
  • 0.00004273Direct
    54001,144232
  • 54001 - Cysteine proteinases
  • 144232 - HIT/MYND zinc finger-like
  • 0.00004273Direct
    57903,53335
  • 57903 - FYVE/PHD zinc finger
  • 53335 - S-adenosyl-L-methionine-dependent methyltransferases
  • 0.00004273Direct
    48092,47655
  • 48092 - Transcription factor STAT-4 N-domain
  • 47655 - STAT
  • 0.00005291Direct
    49417,55550
  • 49417 - p53-like transcription factors
  • 55550 - SH2 domain
  • 0.00007988Direct
    47473,143575
  • 47473 - EF-hand
  • 143575 - GAS2 domain-like
  • 0.00008738Direct
    47459,158457
  • 47459 - HLH, helix-loop-helix DNA-binding domain
  • 158457 - Orange domain-like
  • 0.00008738Direct
    52799,49562
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 0.00009082Direct
    47655,49417
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 0.0001124Direct
    49723,140741
  • 49723 - Lipase/lipooxygenase domain (PLAT/LH2 domain)
  • 140741 - RUN domain-like
  • 0.0001153Direct
    47769,52200
  • 47769 - SAM/Pointed domain
  • 52200 - Toll/Interleukin receptor TIR domain
  • 0.0001153Direct
    48371,47769
  • 48371 - ARM repeat
  • 47769 - SAM/Pointed domain
  • 0.0001153Direct
    57414,57414
  • 57414 - Hairpin loop containing domain-like
  • 57414 - Hairpin loop containing domain-like
  • 0.0001212Direct
    57716,50156
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 50156 - PDZ domain-like
  • 0.0001287Direct
    51556,51338
  • 51556 - Metallo-dependent hydrolases
  • 51338 - Composite domain of metallo-dependent hydrolases
  • 0.0001392Direct
    90229,90229
  • 90229 - CCCH zinc finger
  • 90229 - CCCH zinc finger
  • 0.0001432Direct
    101288,50156
  • 101288 - L27 domain
  • 50156 - PDZ domain-like
  • 0.000168Direct
    49265,49265
  • 49265 - Fibronectin type III
  • 49265 - Fibronectin type III
  • 0.0001814Direct
    57184,49899
  • 57184 - Growth factor receptor domain
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.0002032Direct
    50729,50156
  • 50729 - PH domain-like
  • 50156 - PDZ domain-like
  • 0.0002352Direct
    140741,49723
  • 140741 - RUN domain-like
  • 49723 - Lipase/lipooxygenase domain (PLAT/LH2 domain)
  • 0.0002456Direct
    50729,56112
  • 50729 - PH domain-like
  • 56112 - Protein kinase-like (PK-like)
  • 0.0003086Direct
    81995,82919
  • 81995 - beta-sandwich domain of Sec23/24
  • 82919 - Zn-finger domain of Sec23/24
  • 0.0003117Direct
    52047,52200
  • 52047 - RNI-like
  • 52200 - Toll/Interleukin receptor TIR domain
  • 0.0003123Direct
    49785,57184
  • 49785 - Galactose-binding domain-like
  • 57184 - Growth factor receptor domain
  • 0.0003554Direct
    49899,57603
  • 49899 - Concanavalin A-like lectins/glucanases
  • 57603 - FnI-like domain
  • 0.0004522Direct
    46785,51206
  • 46785 - "Winged helix" DNA-binding domain
  • 51206 - cAMP-binding domain-like
  • 0.0004522Direct
    52058,52047
  • 52058 - L domain-like
  • 52047 - RNI-like
  • 0.0005145Direct
    81271,55186
  • 81271 - TGS-like
  • 55186 - ThrRS/AlaRS common domain
  • 0.0005889Direct
    57440,50494
  • 57440 - Kringle-like
  • 50494 - Trypsin-like serine proteases
  • 0.0005941Direct
    103575,82895
  • 103575 - Plexin repeat
  • 82895 - TSP-1 type 1 repeat
  • 0.0007562Direct
    55550,57850
  • 55550 - SH2 domain
  • 57850 - RING/U-box
  • 0.0008784Direct
    47668,47473
  • 47668 - N-terminal domain of cbl (N-cbl)
  • 47473 - EF-hand
  • 0.0008784Direct
    57716,57716
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 0.08135Inherited
    56487,50494
  • 56487 - SRCR-like
  • 50494 - Trypsin-like serine proteases
  • 0.05235Inherited
    81296,81296
  • 81296 - E set domains
  • 81296 - E set domains
  • 1Inherited
    48452,48452
  • 48452 - TPR-like
  • 48452 - TPR-like
  • 1Inherited
    50729,57889
  • 50729 - PH domain-like
  • 57889 - Cysteine-rich domain
  • 0.005334Inherited
    52540,48452
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 48452 - TPR-like
  • 0.005624Inherited
    47986,47986
  • 47986 - DEATH domain
  • 47986 - DEATH domain
  • 1Inherited
    49899,54001
  • 49899 - Concanavalin A-like lectins/glucanases
  • 54001 - Cysteine proteinases
  • 0.1918Inherited
    54001,49758
  • 54001 - Cysteine proteinases
  • 49758 - Calpain large subunit, middle domain (domain III)
  • 0.2348Inherited
    48371,48371
  • 48371 - ARM repeat
  • 48371 - ARM repeat
  • 0.0868Inherited
    52540,52540
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 1Inherited
    55486,50923
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 50923 - Hemopexin-like domain
  • 0.1379Inherited
    55550,55550
  • 55550 - SH2 domain
  • 55550 - SH2 domain
  • 0.2834Inherited
    47090,55486
  • 47090 - PGBD-like
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 0.1138Inherited
    57630,57184
  • 57630 - GLA-domain
  • 57184 - Growth factor receptor domain
  • 0.187Inherited
    47413,46689
  • 47413 - lambda repressor-like DNA-binding domains
  • 46689 - Homeodomain-like
  • 0.403Inherited
    47986,52540
  • 47986 - DEATH domain
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 1Inherited
    57889,49562
  • 57889 - Cysteine-rich domain
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 0.01691Inherited
    49562,56112
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 56112 - Protein kinase-like (PK-like)
  • 0.0786Inherited
    57889,57889
  • 57889 - Cysteine-rich domain
  • 57889 - Cysteine-rich domain
  • 1Inherited
    54452,48726
  • 54452 - MHC antigen-recognition domain
  • 48726 - Immunoglobulin
  • 0.5588Inherited
    55550,56112
  • 55550 - SH2 domain
  • 56112 - Protein kinase-like (PK-like)
  • 0.3675Inherited
    56487,56487
  • 56487 - SRCR-like
  • 56487 - SRCR-like
  • 0.04645Inherited
    53850,53850
  • 53850 - Periplasmic binding protein-like II
  • 53850 - Periplasmic binding protein-like II
  • 0.05591Inherited
    47454,57959
  • 47454 - A DNA-binding domain in eukaryotic transcription factors
  • 57959 - Leucine zipper domain
  • 0.03729Inherited
    46689,46689
  • 46689 - Homeodomain-like
  • 46689 - Homeodomain-like
  • 0.1283Inherited
    54768,54768
  • 54768 - dsRNA-binding domain-like
  • 54768 - dsRNA-binding domain-like
  • 0.1134Inherited
    53067,53067
  • 53067 - Actin-like ATPase domain
  • 53067 - Actin-like ATPase domain
  • 1Inherited
    56436,82153
  • 56436 - C-type lectin-like
  • 82153 - FAS1 domain
  • 0.02053Inherited
    82153,82153
  • 82153 - FAS1 domain
  • 82153 - FAS1 domain
  • 0.4119Inherited
    57603,82895
  • 57603 - FnI-like domain
  • 82895 - TSP-1 type 1 repeat
  • 0.05591Inherited
    103647,49899
  • 103647 - TSP type-3 repeat
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.1379Inherited
    103647,103647
  • 103647 - TSP type-3 repeat
  • 103647 - TSP type-3 repeat
  • 0.1379Inherited
    56436,56436
  • 56436 - C-type lectin-like
  • 56436 - C-type lectin-like
  • 0.3098Inherited
    55550,50044
  • 55550 - SH2 domain
  • 50044 - SH3-domain
  • 1Inherited
    57196,82153
  • 57196 - EGF/Laminin
  • 82153 - FAS1 domain
  • 0.1918Inherited
    47384,55874
  • 47384 - Homodimeric domain of signal transducing histidine kinase
  • 55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
  • 0.9735Inherited
    52172,52172
  • 52172 - CheY-like
  • 52172 - CheY-like
  • 0.008814Inherited
    56112,54427
  • 56112 - Protein kinase-like (PK-like)
  • 54427 - NTF2-like
  • 0.954Inherited
    49562,48350
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 48350 - GTPase activation domain, GAP
  • 0.6755Inherited
    49854,49785
  • 49854 - Spermadhesin, CUB domain
  • 49785 - Galactose-binding domain-like
  • 0.0786Inherited
    49785,49899
  • 49785 - Galactose-binding domain-like
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.0786Inherited
    49854,49854
  • 49854 - Spermadhesin, CUB domain
  • 49854 - Spermadhesin, CUB domain
  • 0.187Inherited
    49785,49785
  • 49785 - Galactose-binding domain-like
  • 49785 - Galactose-binding domain-like
  • 0.772Inherited
    53300,69179
  • 53300 - vWA-like
  • 69179 - Integrin domains
  • 1Inherited
    54791,54791
  • 54791 - Eukaryotic type KH-domain (KH-domain type I)
  • 54791 - Eukaryotic type KH-domain (KH-domain type I)
  • 0.06441Inherited
    55550,158235
  • 55550 - SH2 domain
  • 158235 - SOCS box-like
  • 0.003407Inherited
    49265,56496
  • 49265 - Fibronectin type III
  • 56496 - Fibrinogen C-terminal domain-like
  • 0.05591Inherited
    51069,49265
  • 51069 - Carbonic anhydrase
  • 49265 - Fibronectin type III
  • 0.05029Inherited
    47031,50729
  • 47031 - Second domain of FERM
  • 50729 - PH domain-like
  • 0.9145Inherited
    54403,54403
  • 54403 - Cystatin/monellin
  • 54403 - Cystatin/monellin
  • 0.005334Inherited
    90188,53649
  • 90188 - Somatomedin B domain
  • 53649 - Alkaline phosphatase-like
  • 0.3306Inherited
    90188,90188
  • 90188 - Somatomedin B domain
  • 90188 - Somatomedin B domain
  • 0.5093Inherited
    47473,55550
  • 47473 - EF-hand
  • 55550 - SH2 domain
  • 0.001174Inherited
    46785,144074
  • 46785 - "Winged helix" DNA-binding domain
  • 144074 - E2F-DP heterodimerization region
  • 0.9461Inherited
    54160,54160
  • 54160 - Chromo domain-like
  • 54160 - Chromo domain-like
  • 0.00217Inherited
    57716,48508
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 48508 - Nuclear receptor ligand-binding domain
  • 1Inherited
    57903,47370
  • 57903 - FYVE/PHD zinc finger
  • 47370 - Bromodomain
  • 0.2237Inherited
    47370,63748
  • 47370 - Bromodomain
  • 63748 - Tudor/PWWP/MBT
  • 0.005624Inherited
    50044,52540
  • 50044 - SH3-domain
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.02943Inherited
    56112,50978
  • 56112 - Protein kinase-like (PK-like)
  • 50978 - WD40 repeat-like
  • 0.001728Inherited
    52058,52540
  • 52058 - L domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.4475Inherited
    49348,55711
  • 49348 - Clathrin adaptor appendage domain
  • 55711 - Subdomain of clathrin and coatomer appendage domain
  • 0.1048Inherited
    48726,56112
  • 48726 - Immunoglobulin
  • 56112 - Protein kinase-like (PK-like)
  • 0.1227Inherited
    63501,50242
  • 63501 - Frizzled cysteine-rich domain
  • 50242 - TIMP-like
  • 0.00217Inherited
    51045,51045
  • 51045 - WW domain
  • 51045 - WW domain
  • 0.08245Inherited
    52058,57184
  • 52058 - L domain-like
  • 57184 - Growth factor receptor domain
  • 0.06315Inherited
    57184,52058
  • 57184 - Growth factor receptor domain
  • 52058 - L domain-like
  • 0.06315Inherited
    52743,49785
  • 52743 - Subtilisin-like
  • 49785 - Galactose-binding domain-like
  • 0.327Inherited
    48403,48403
  • 48403 - Ankyrin repeat
  • 48403 - Ankyrin repeat
  • 0.7885Inherited
    54897,52743
  • 54897 - Protease propeptides/inhibitors
  • 52743 - Subtilisin-like
  • 0.8212Inherited
    100895,100895
  • 100895 - Kazal-type serine protease inhibitors
  • 100895 - Kazal-type serine protease inhibitors
  • 0.1507Inherited
    54236,47031
  • 54236 - Ubiquitin-like
  • 47031 - Second domain of FERM
  • 0.7684Inherited
    54928,54928
  • 54928 - RNA-binding domain, RBD
  • 54928 - RNA-binding domain, RBD
  • 0.291Inherited
    57196,63825
  • 57196 - EGF/Laminin
  • 63825 - YWTD domain
  • 0.04645Inherited
    63825,57196
  • 63825 - YWTD domain
  • 57196 - EGF/Laminin
  • 0.0714Inherited
    49265,49899
  • 49265 - Fibronectin type III
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.2348Inherited
    49562,49562
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 0.8766Inherited
    50729,50044
  • 50729 - PH domain-like
  • 50044 - SH3-domain
  • 0.01198Inherited
    50044,55550
  • 50044 - SH3-domain
  • 55550 - SH2 domain
  • 0.892Inherited
    47473,50729
  • 47473 - EF-hand
  • 50729 - PH domain-like
  • 0.1918Inherited
    49562,53300
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 53300 - vWA-like
  • 0.0786Inherited
    55753,82754
  • 55753 - Actin depolymerizing proteins
  • 82754 - C-terminal, gelsolin-like domain of Sec23/24
  • 0.5743Inherited
    82754,55753
  • 82754 - C-terminal, gelsolin-like domain of Sec23/24
  • 55753 - Actin depolymerizing proteins
  • 0.5743Inherited
    57288,57288
  • 57288 - Midkine
  • 57288 - Midkine
  • 0.005508Inherited
    53300,81995
  • 53300 - vWA-like
  • 81995 - beta-sandwich domain of Sec23/24
  • 0.004488Inherited
    81995,81811
  • 81995 - beta-sandwich domain of Sec23/24
  • 81811 - Helical domain of Sec23/24
  • 0.01405Inherited
    81811,82754
  • 81811 - Helical domain of Sec23/24
  • 82754 - C-terminal, gelsolin-like domain of Sec23/24
  • 0.001079Inherited
    55753,47050
  • 55753 - Actin depolymerizing proteins
  • 47050 - VHP, Villin headpiece domain
  • 0.9461Inherited
    50156,52540
  • 50156 - PDZ domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.01819Inherited
    51045,50156
  • 51045 - WW domain
  • 50156 - PDZ domain-like
  • 0.01077Inherited
    48403,82199
  • 48403 - Ankyrin repeat
  • 82199 - SET domain
  • 0.01077Inherited
    52540,51045
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 51045 - WW domain
  • 0.0361Inherited
    49562,57889
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 57889 - Cysteine-rich domain
  • 1Inherited
    47473,47473
  • 47473 - EF-hand
  • 47473 - EF-hand
  • 0.1322Inherited
    57424,57424
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 0.1646Inherited
    51338,51556
  • 51338 - Composite domain of metallo-dependent hydrolases
  • 51556 - Metallo-dependent hydrolases
  • 0.001504Inherited
    56112,56112
  • 56112 - Protein kinase-like (PK-like)
  • 56112 - Protein kinase-like (PK-like)
  • 0.8964Inherited
    51905,51905
  • 51905 - FAD/NAD(P)-binding domain
  • 51905 - FAD/NAD(P)-binding domain
  • 0.7159Inherited
    57424,57184
  • 57424 - LDL receptor-like module
  • 57184 - Growth factor receptor domain
  • 0.008058Inherited
    57184,63825
  • 57184 - Growth factor receptor domain
  • 63825 - YWTD domain
  • 0.01861Inherited
    47473,57610
  • 47473 - EF-hand
  • 57610 - Thyroglobulin type-1 domain
  • 0.008351Inherited
    54534,48452
  • 54534 - FKBP-like
  • 48452 - TPR-like
  • 0.02099Inherited
    100895,47473
  • 100895 - Kazal-type serine protease inhibitors
  • 47473 - EF-hand
  • 0.02613Inherited
    54534,54534
  • 54534 - FKBP-like
  • 54534 - FKBP-like
  • 0.0786Inherited
    51045,56204
  • 51045 - WW domain
  • 56204 - Hect, E3 ligase catalytic domain
  • 0.03831Inherited
    50978,50998
  • 50978 - WD40 repeat-like
  • 50998 - Quinoprotein alcohol dehydrogenase-like
  • 0.1227Inherited
    52283,51735
  • 52283 - Formate/glycerate dehydrogenase catalytic domain-like
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 0.03015Inherited
    52047,52058
  • 52047 - RNI-like
  • 52058 - L domain-like
  • 1Inherited
    57196,90193
  • 57196 - EGF/Laminin
  • 90193 - Notch domain
  • 0.003407Inherited
    90193,90193
  • 90193 - Notch domain
  • 90193 - Notch domain
  • 0.003407Inherited
    57184,57184
  • 57184 - Growth factor receptor domain
  • 57184 - Growth factor receptor domain
  • 0.02118Inherited
    48371,56112
  • 48371 - ARM repeat
  • 56112 - Protein kinase-like (PK-like)
  • 0.8785Inherited
    47986,52129
  • 47986 - DEATH domain
  • 52129 - Caspase-like
  • 0.8059Inherited
    49562,48371
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 48371 - ARM repeat
  • 1Inherited
    46966,47473
  • 46966 - Spectrin repeat
  • 47473 - EF-hand
  • 0.6169Inherited
    63748,63748
  • 63748 - Tudor/PWWP/MBT
  • 63748 - Tudor/PWWP/MBT
  • 0.001382Inherited
    57440,57440
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 0.01003Inherited
    47459,55785
  • 47459 - HLH, helix-loop-helix DNA-binding domain
  • 55785 - PYP-like sensor domain (PAS domain)
  • 0.03493Inherited
    47954,47954
  • 47954 - Cyclin-like
  • 47954 - Cyclin-like
  • 1Inherited
    57850,48371
  • 57850 - RING/U-box
  • 48371 - ARM repeat
  • 0.03081Inherited
    50729,55550
  • 50729 - PH domain-like
  • 55550 - SH2 domain
  • 0.5743Inherited
    57850,49599
  • 57850 - RING/U-box
  • 49599 - TRAF domain-like
  • 0.3306Inherited
    55785,55785
  • 55785 - PYP-like sensor domain (PAS domain)
  • 55785 - PYP-like sensor domain (PAS domain)
  • 0.8162Inherited
    49313,49313
  • 49313 - Cadherin-like
  • 49313 - Cadherin-like
  • 0.004163Inherited
    52113,52113
  • 52113 - BRCT domain
  • 52113 - BRCT domain
  • 0.003407Inherited
    48065,50729
  • 48065 - DBL homology domain (DH-domain)
  • 50729 - PH domain-like
  • 0.1704Inherited
    117281,117281
  • 117281 - Kelch motif
  • 117281 - Kelch motif
  • 0.002335Inherited
    46966,46966
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 0.291Inherited
    48726,57196
  • 48726 - Immunoglobulin
  • 57196 - EGF/Laminin
  • 0.005334Inherited
    57196,69687
  • 57196 - EGF/Laminin
  • 69687 - Integrin beta tail domain
  • 1Inherited
    55186,55681
  • 55186 - ThrRS/AlaRS common domain
  • 55681 - Class II aaRS and biotin synthetases
  • 0.001031Inherited
    55681,52954
  • 55681 - Class II aaRS and biotin synthetases
  • 52954 - Class II aaRS ABD-related
  • 0.3686Inherited
    50677,52374
  • 50677 - ValRS/IleRS/LeuRS editing domain
  • 52374 - Nucleotidylyl transferase
  • 0.4938Inherited
    48552,48552
  • 48552 - Serum albumin-like
  • 48552 - Serum albumin-like
  • 0.1918Inherited
    57535,57535
  • 57535 - Complement control module/SCR domain
  • 57535 - Complement control module/SCR domain
  • 0.08107Inherited
    51445,54556
  • 51445 - (Trans)glycosidases
  • 54556 - Chitinase insertion domain
  • 0.01277Inherited
    49723,48484
  • 49723 - Lipase/lipooxygenase domain (PLAT/LH2 domain)
  • 48484 - Lipoxigenase
  • 0.6169Inherited
    57603,57603
  • 57603 - FnI-like domain
  • 57603 - FnI-like domain
  • 0.02641Inherited
    57667,57667
  • 57667 - beta-beta-alpha zinc fingers
  • 57667 - beta-beta-alpha zinc fingers
  • 0.009177Inherited
    69065,54768
  • 69065 - RNase III domain-like
  • 54768 - dsRNA-binding domain-like
  • 0.05029Inherited
    81606,81601
  • 81606 - PP2C-like
  • 81601 - Protein serine/threonine phosphatase 2C, C-terminal domain
  • 0.8412Inherited
    47212,56112
  • 47212 - FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP)
  • 56112 - Protein kinase-like (PK-like)
  • 0.02053Inherited
    55753,55753
  • 55753 - Actin depolymerizing proteins
  • 55753 - Actin depolymerizing proteins
  • 0.6747Inherited
    56491,89811
  • 56491 - A heparin-binding domain
  • 89811 - Amyloid beta a4 protein copper binding domain (domain 2)
  • 0.9193Inherited
    57362,109843
  • 57362 - BPTI-like
  • 109843 - CAPPD, an extracellular domain of amyloid beta A4 protein
  • 1Inherited
    81901,48452
  • 81901 - HCP-like
  • 48452 - TPR-like
  • 0.01819Inherited
    48452,81901
  • 48452 - TPR-like
  • 81901 - HCP-like
  • 0.1918Inherited
    53067,100920
  • 53067 - Actin-like ATPase domain
  • 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
  • 0.5786Inherited
    57903,57903
  • 57903 - FYVE/PHD zinc finger
  • 57903 - FYVE/PHD zinc finger
  • 0.06882Inherited
    57196,50494
  • 57196 - EGF/Laminin
  • 50494 - Trypsin-like serine proteases
  • 1Inherited
    57184,57196
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 0.002898Inherited
    57630,57196
  • 57630 - GLA-domain
  • 57196 - EGF/Laminin
  • 0.7885Inherited
    57586,57586
  • 57586 - TNF receptor-like
  • 57586 - TNF receptor-like
  • 0.3879Inherited
    47473,51695
  • 47473 - EF-hand
  • 51695 - PLC-like phosphodiesterases
  • 0.2951Inherited
    50729,47473
  • 50729 - PH domain-like
  • 47473 - EF-hand
  • 0.7563Inherited
    101912,103575
  • 101912 - Sema domain
  • 103575 - Plexin repeat
  • 0.9596Inherited
    82895,82895
  • 82895 - TSP-1 type 1 repeat
  • 82895 - TSP-1 type 1 repeat
  • 0.03711Inherited
    52058,52058
  • 52058 - L domain-like
  • 52058 - L domain-like
  • 0.9579Inherited
    57184,57581
  • 57184 - Growth factor receptor domain
  • 57581 - TB module/8-cys domain
  • 0.1166Inherited
    57196,57581
  • 57196 - EGF/Laminin
  • 57581 - TB module/8-cys domain
  • 0.2505Inherited
    57581,57196
  • 57581 - TB module/8-cys domain
  • 57196 - EGF/Laminin
  • 0.2505Inherited
    54236,54236
  • 54236 - Ubiquitin-like
  • 54236 - Ubiquitin-like
  • 0.187Inherited
    81383,50978
  • 81383 - F-box domain
  • 50978 - WD40 repeat-like
  • 0.08099Inherited
    49854,57535
  • 49854 - Spermadhesin, CUB domain
  • 57535 - Complement control module/SCR domain
  • 0.1084Inherited
    57196,50242
  • 57196 - EGF/Laminin
  • 50242 - TIMP-like
  • 0.001382Inherited
    57889,48350
  • 57889 - Cysteine-rich domain
  • 48350 - GTPase activation domain, GAP
  • 0.3306Inherited
    82615,82615
  • 82615 - Polo-box domain
  • 82615 - Polo-box domain
  • 0.01381Inherited
    57535,49854
  • 57535 - Complement control module/SCR domain
  • 49854 - Spermadhesin, CUB domain
  • 0.003312Inherited
    57424,57196
  • 57424 - LDL receptor-like module
  • 57196 - EGF/Laminin
  • 0.2505Inherited
    50729,49562
  • 50729 - PH domain-like
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 0.002482Inherited
    55945,48150
  • 55945 - TATA-box binding protein-like
  • 48150 - DNA-glycosylase
  • 0.003791Inherited
    48350,55961
  • 48350 - GTPase activation domain, GAP
  • 55961 - Bet v1-like
  • 0.0786Inherited
    55486,57552
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 57552 - Blood coagulation inhibitor (disintegrin)
  • 0.3212Inherited
    50156,50729
  • 50156 - PDZ domain-like
  • 50729 - PH domain-like
  • 0.2505Inherited
    75632,46785
  • 75632 - Cullin homology domain
  • 46785 - "Winged helix" DNA-binding domain
  • 0.01198Inherited
    54160,52540
  • 54160 - Chromo domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.0131Inherited
    74788,75632
  • 74788 - Cullin repeat-like
  • 75632 - Cullin homology domain
  • 0.1166Inherited
    50729,50729
  • 50729 - PH domain-like
  • 50729 - PH domain-like
  • 1Inherited
    56801,47336
  • 56801 - Acetyl-CoA synthetase-like
  • 47336 - ACP-like
  • 0.7922Inherited
    50044,50044
  • 50044 - SH3-domain
  • 50044 - SH3-domain
  • 0.414Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    57630,57196,57184
  • 57630 - GLA-domain
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 0Direct
    75399,46966,46966
  • 75399 - Plakin repeat
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 0Direct
    103652,50729,57889
  • 103652 - G protein-binding domain
  • 50729 - PH domain-like
  • 57889 - Cysteine-rich domain
  • 0Direct
    50729,50156,50729
  • 50729 - PH domain-like
  • 50156 - PDZ domain-like
  • 50729 - PH domain-like
  • 0Direct
    52058,48726,48726
  • 52058 - L domain-like
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 0Direct
    48350,48371,52087
  • 48350 - GTPase activation domain, GAP
  • 48371 - ARM repeat
  • 52087 - CRAL/TRIO domain
  • 0Direct
    57184,57184,82153
  • 57184 - Growth factor receptor domain
  • 57184 - Growth factor receptor domain
  • 82153 - FAS1 domain
  • 0Direct
    55550,50044,50729
  • 55550 - SH2 domain
  • 50044 - SH3-domain
  • 50729 - PH domain-like
  • 0Direct
    47473,47473,57997
  • 47473 - EF-hand
  • 47473 - EF-hand
  • 57997 - Tropomyosin
  • 0Direct
    57184,82153,82153
  • 57184 - Growth factor receptor domain
  • 82153 - FAS1 domain
  • 82153 - FAS1 domain
  • 0Direct
    63763,47095,47095
  • 63763 - SAND domain-like
  • 47095 - HMG-box
  • 47095 - HMG-box
  • 0Direct
    47473,51695,55550
  • 47473 - EF-hand
  • 51695 - PLC-like phosphodiesterases
  • 55550 - SH2 domain
  • 0Direct
    48726,48726,49265
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 0Direct
    55550,55550,56112
  • 55550 - SH2 domain
  • 55550 - SH2 domain
  • 56112 - Protein kinase-like (PK-like)
  • 0Direct
    52058,57184,57184
  • 52058 - L domain-like
  • 57184 - Growth factor receptor domain
  • 57184 - Growth factor receptor domain
  • 0Direct
    57196,57196,100895
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 100895 - Kazal-type serine protease inhibitors
  • 0Direct
    63748,48371,49785
  • 63748 - Tudor/PWWP/MBT
  • 48371 - ARM repeat
  • 49785 - Galactose-binding domain-like
  • 0Direct
    51695,55550,55550
  • 51695 - PLC-like phosphodiesterases
  • 55550 - SH2 domain
  • 55550 - SH2 domain
  • 0Direct
    49265,48726,49265
  • 49265 - Fibronectin type III
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 9.676e-16Direct
    49899,57196,57196
  • 49899 - Concanavalin A-like lectins/glucanases
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.000000000000002832Direct
    49899,48726,49265
  • 49899 - Concanavalin A-like lectins/glucanases
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 0.00000000000006739Direct
    57196,49899,49899
  • 57196 - EGF/Laminin
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.00000000000009555Direct
    57196,57196,49899
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.000000000000558Direct
    47576,46966,46966
  • 47576 - Calponin-homology domain, CH-domain
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 0.000000000002956Direct
    48726,48726,48726
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 0.000000000004306Direct
    82895,82895,57196
  • 82895 - TSP-1 type 1 repeat
  • 82895 - TSP-1 type 1 repeat
  • 57196 - EGF/Laminin
  • 0.0000000001274Direct
    101912,103575,48726
  • 101912 - Sema domain
  • 103575 - Plexin repeat
  • 48726 - Immunoglobulin
  • 0.0000000001757Direct
    48065,50729,50044
  • 48065 - DBL homology domain (DH-domain)
  • 50729 - PH domain-like
  • 50044 - SH3-domain
  • 0.0000000004978Direct
    57196,57184,49899
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.0000000007394Direct
    57603,82895,82895
  • 57603 - FnI-like domain
  • 82895 - TSP-1 type 1 repeat
  • 82895 - TSP-1 type 1 repeat
  • 0.000000001365Direct
    49785,57184,49265
  • 49785 - Galactose-binding domain-like
  • 57184 - Growth factor receptor domain
  • 49265 - Fibronectin type III
  • 0.000000001393Direct
    49899,49899,57196
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49899 - Concanavalin A-like lectins/glucanases
  • 57196 - EGF/Laminin
  • 0.00000000177Direct
    51338,51556,51338
  • 51338 - Composite domain of metallo-dependent hydrolases
  • 51556 - Metallo-dependent hydrolases
  • 51338 - Composite domain of metallo-dependent hydrolases
  • 0.000000009433Direct
    57184,49899,57196
  • 57184 - Growth factor receptor domain
  • 49899 - Concanavalin A-like lectins/glucanases
  • 57196 - EGF/Laminin
  • 0.00000001062Direct
    57414,57440,57440
  • 57414 - Hairpin loop containing domain-like
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 0.0000000585Direct
    52025,53187,47672
  • 52025 - PA domain
  • 53187 - Zn-dependent exopeptidases
  • 47672 - Transferrin receptor-like dimerisation domain
  • 0.0000004211Direct
    48726,82895,82895
  • 48726 - Immunoglobulin
  • 82895 - TSP-1 type 1 repeat
  • 82895 - TSP-1 type 1 repeat
  • 0.0000004439Direct
    57184,57196,49899
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.0000005007Direct
    48726,48726,82895
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 82895 - TSP-1 type 1 repeat
  • 0.0000006371Direct
    49313,49313,49899
  • 49313 - Cadherin-like
  • 49313 - Cadherin-like
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.000000643Direct
    49417,110217,81296
  • 49417 - p53-like transcription factors
  • 110217 - DNA-binding protein LAG-1 (CSL)
  • 81296 - E set domains
  • 0.000001079Direct
    49265,49265,56496
  • 49265 - Fibronectin type III
  • 49265 - Fibronectin type III
  • 56496 - Fibrinogen C-terminal domain-like
  • 0.000001638Direct
    57440,57440,57440
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 0.00000233Direct
    52058,57196,57196
  • 52058 - L domain-like
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.000003401Direct
    57196,57196,57184
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 0.000007988Direct
    57196,49899,57196
  • 57196 - EGF/Laminin
  • 49899 - Concanavalin A-like lectins/glucanases
  • 57196 - EGF/Laminin
  • 0.000008733Direct
    49899,57603,57603
  • 49899 - Concanavalin A-like lectins/glucanases
  • 57603 - FnI-like domain
  • 57603 - FnI-like domain
  • 0.000009783Direct
    57196,57184,57196
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 0.00001461Direct
    50156,50044,52540
  • 50156 - PDZ domain-like
  • 50044 - SH3-domain
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.00001461Direct
    63748,63748,63748
  • 63748 - Tudor/PWWP/MBT
  • 63748 - Tudor/PWWP/MBT
  • 63748 - Tudor/PWWP/MBT
  • 0.00001707Direct
    57196,57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.00002005Direct
    57630,57184,57196
  • 57630 - GLA-domain
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 0.00004273Direct
    50242,100895,100895
  • 50242 - TIMP-like
  • 100895 - Kazal-type serine protease inhibitors
  • 100895 - Kazal-type serine protease inhibitors
  • 0.00004273Direct
    48092,47655,49417
  • 48092 - Transcription factor STAT-4 N-domain
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 0.00005291Direct
    48726,49265,49265
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 49265 - Fibronectin type III
  • 0.00006135Direct
    57440,57440,50494
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 50494 - Trypsin-like serine proteases
  • 0.00009752Direct
    47769,47769,52200
  • 47769 - SAM/Pointed domain
  • 47769 - SAM/Pointed domain
  • 52200 - Toll/Interleukin receptor TIR domain
  • 0.0001153Direct
    48371,47769,47769
  • 48371 - ARM repeat
  • 47769 - SAM/Pointed domain
  • 47769 - SAM/Pointed domain
  • 0.0001153Direct
    52058,52058,57196
  • 52058 - L domain-like
  • 52058 - L domain-like
  • 57196 - EGF/Laminin
  • 0.0001153Direct
    140741,49723,140741
  • 140741 - RUN domain-like
  • 49723 - Lipase/lipooxygenase domain (PLAT/LH2 domain)
  • 140741 - RUN domain-like
  • 0.0001153Direct
    57196,57184,57581
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 57581 - TB module/8-cys domain
  • 0.0001153Direct
    57716,57716,50156
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 50156 - PDZ domain-like
  • 0.0001287Direct
    47655,49417,55550
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 55550 - SH2 domain
  • 0.0001577Direct
    52058,52047,52200
  • 52058 - L domain-like
  • 52047 - RNI-like
  • 52200 - Toll/Interleukin receptor TIR domain
  • 0.0002058Direct
    81995,82919,53300
  • 81995 - beta-sandwich domain of Sec23/24
  • 82919 - Zn-finger domain of Sec23/24
  • 53300 - vWA-like
  • 0.0003117Direct
    81271,55186,55681
  • 81271 - TGS-like
  • 55186 - ThrRS/AlaRS common domain
  • 55681 - Class II aaRS and biotin synthetases
  • 0.000389Direct
    55753,55753,82754
  • 55753 - Actin depolymerizing proteins
  • 55753 - Actin depolymerizing proteins
  • 82754 - C-terminal, gelsolin-like domain of Sec23/24
  • 0.0004177Direct
    54534,54534,48452
  • 54534 - FKBP-like
  • 54534 - FKBP-like
  • 48452 - TPR-like
  • 0.0004177Direct
    57581,57196,57184
  • 57581 - TB module/8-cys domain
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 0.0005889Direct
    48726,49265,49899
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.0007562Direct
    101912,103575,82895
  • 101912 - Sema domain
  • 103575 - Plexin repeat
  • 82895 - TSP-1 type 1 repeat
  • 0.0007562Direct
    103575,82895,82895
  • 103575 - Plexin repeat
  • 82895 - TSP-1 type 1 repeat
  • 82895 - TSP-1 type 1 repeat
  • 0.0007562Direct
    52540,48452,48452
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 48452 - TPR-like
  • 48452 - TPR-like
  • 0.0007562Direct
    55186,55681,52954
  • 55186 - ThrRS/AlaRS common domain
  • 55681 - Class II aaRS and biotin synthetases
  • 52954 - Class II aaRS ABD-related
  • 0.0008625Direct
    47668,47473,55550
  • 47668 - N-terminal domain of cbl (N-cbl)
  • 47473 - EF-hand
  • 55550 - SH2 domain
  • 0.0008784Direct
    47473,55550,57850
  • 47473 - EF-hand
  • 55550 - SH2 domain
  • 57850 - RING/U-box
  • 0.0008784Direct
    81296,81296,81296
  • 81296 - E set domains
  • 81296 - E set domains
  • 81296 - E set domains
  • 1Inherited
    49899,54001,49758
  • 49899 - Concanavalin A-like lectins/glucanases
  • 54001 - Cysteine proteinases
  • 49758 - Calpain large subunit, middle domain (domain III)
  • 0.1918Inherited
    47090,55486,50923
  • 47090 - PGBD-like
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 50923 - Hemopexin-like domain
  • 0.05591Inherited
    57630,57184,49899
  • 57630 - GLA-domain
  • 57184 - Growth factor receptor domain
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.1227Inherited
    57889,57889,49562
  • 57889 - Cysteine-rich domain
  • 57889 - Cysteine-rich domain
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 0.0131Inherited
    57889,49562,56112
  • 57889 - Cysteine-rich domain
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 56112 - Protein kinase-like (PK-like)
  • 0.0786Inherited
    56487,56487,56487
  • 56487 - SRCR-like
  • 56487 - SRCR-like
  • 56487 - SRCR-like
  • 0.005414Inherited
    50729,55550,56112
  • 50729 - PH domain-like
  • 55550 - SH2 domain
  • 56112 - Protein kinase-like (PK-like)
  • 0.5452Inherited
    55550,56112,56112
  • 55550 - SH2 domain
  • 56112 - Protein kinase-like (PK-like)
  • 56112 - Protein kinase-like (PK-like)
  • 0.429Inherited
    57667,57667,57667
  • 57667 - beta-beta-alpha zinc fingers
  • 57667 - beta-beta-alpha zinc fingers
  • 57667 - beta-beta-alpha zinc fingers
  • 0.08192Inherited
    103647,103647,49899
  • 103647 - TSP type-3 repeat
  • 103647 - TSP type-3 repeat
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.1379Inherited
    103647,103647,103647
  • 103647 - TSP type-3 repeat
  • 103647 - TSP type-3 repeat
  • 103647 - TSP type-3 repeat
  • 0.1379Inherited
    55550,55550,50044
  • 55550 - SH2 domain
  • 55550 - SH2 domain
  • 50044 - SH3-domain
  • 0.8059Inherited
    57196,82153,82153
  • 57196 - EGF/Laminin
  • 82153 - FAS1 domain
  • 82153 - FAS1 domain
  • 0.1918Inherited
    49854,49785,49785
  • 49854 - Spermadhesin, CUB domain
  • 49785 - Galactose-binding domain-like
  • 49785 - Galactose-binding domain-like
  • 0.0786Inherited
    49854,49854,49785
  • 49854 - Spermadhesin, CUB domain
  • 49854 - Spermadhesin, CUB domain
  • 49785 - Galactose-binding domain-like
  • 0.0786Inherited
    49785,49785,49899
  • 49785 - Galactose-binding domain-like
  • 49785 - Galactose-binding domain-like
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.0786Inherited
    49265,49265,49265
  • 49265 - Fibronectin type III
  • 49265 - Fibronectin type III
  • 49265 - Fibronectin type III
  • 0.1665Inherited
    47031,50729,56112
  • 47031 - Second domain of FERM
  • 50729 - PH domain-like
  • 56112 - Protein kinase-like (PK-like)
  • 0.327Inherited
    90188,90188,53649
  • 90188 - Somatomedin B domain
  • 90188 - Somatomedin B domain
  • 53649 - Alkaline phosphatase-like
  • 0.3306Inherited
    55753,82754,55753
  • 55753 - Actin depolymerizing proteins
  • 82754 - C-terminal, gelsolin-like domain of Sec23/24
  • 55753 - Actin depolymerizing proteins
  • 0.001093Inherited
    55753,55753,55753
  • 55753 - Actin depolymerizing proteins
  • 55753 - Actin depolymerizing proteins
  • 55753 - Actin depolymerizing proteins
  • 0.7184Inherited
    57903,47370,63748
  • 57903 - FYVE/PHD zinc finger
  • 47370 - Bromodomain
  • 63748 - Tudor/PWWP/MBT
  • 0.002434Inherited
    48726,48726,56112
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 56112 - Protein kinase-like (PK-like)
  • 0.1227Inherited
    57184,49899,49899
  • 57184 - Growth factor receptor domain
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.00217Inherited
    52058,57184,52058
  • 52058 - L domain-like
  • 57184 - Growth factor receptor domain
  • 52058 - L domain-like
  • 0.06315Inherited
    48403,48403,48403
  • 48403 - Ankyrin repeat
  • 48403 - Ankyrin repeat
  • 48403 - Ankyrin repeat
  • 0.1227Inherited
    49899,57196,49899
  • 49899 - Concanavalin A-like lectins/glucanases
  • 57196 - EGF/Laminin
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.002576Inherited
    54897,52743,49785
  • 54897 - Protease propeptides/inhibitors
  • 52743 - Subtilisin-like
  • 49785 - Galactose-binding domain-like
  • 0.1918Inherited
    100895,100895,100895
  • 100895 - Kazal-type serine protease inhibitors
  • 100895 - Kazal-type serine protease inhibitors
  • 100895 - Kazal-type serine protease inhibitors
  • 0.187Inherited
    54236,47031,50729
  • 54236 - Ubiquitin-like
  • 47031 - Second domain of FERM
  • 50729 - PH domain-like
  • 0.7421Inherited
    57196,63825,57196
  • 57196 - EGF/Laminin
  • 63825 - YWTD domain
  • 57196 - EGF/Laminin
  • 0.02641Inherited
    82895,82895,82895
  • 82895 - TSP-1 type 1 repeat
  • 82895 - TSP-1 type 1 repeat
  • 82895 - TSP-1 type 1 repeat
  • 0.2438Inherited
    50044,55550,56112
  • 50044 - SH3-domain
  • 55550 - SH2 domain
  • 56112 - Protein kinase-like (PK-like)
  • 0.8597Inherited
    49562,49562,53300
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 53300 - vWA-like
  • 0.0786Inherited
    82754,55753,55753
  • 82754 - C-terminal, gelsolin-like domain of Sec23/24
  • 55753 - Actin depolymerizing proteins
  • 55753 - Actin depolymerizing proteins
  • 0.5743Inherited
    82919,53300,81995
  • 82919 - Zn-finger domain of Sec23/24
  • 53300 - vWA-like
  • 81995 - beta-sandwich domain of Sec23/24
  • 0.003898Inherited
    81995,81811,82754
  • 81995 - beta-sandwich domain of Sec23/24
  • 81811 - Helical domain of Sec23/24
  • 82754 - C-terminal, gelsolin-like domain of Sec23/24
  • 0.01405Inherited
    53300,81995,81811
  • 53300 - vWA-like
  • 81995 - beta-sandwich domain of Sec23/24
  • 81811 - Helical domain of Sec23/24
  • 0.01405Inherited
    55753,55753,47050
  • 55753 - Actin depolymerizing proteins
  • 55753 - Actin depolymerizing proteins
  • 47050 - VHP, Villin headpiece domain
  • 0.9461Inherited
    57196,57196,63825
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 63825 - YWTD domain
  • 0.005508Inherited
    52540,51045,51045
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 51045 - WW domain
  • 51045 - WW domain
  • 0.02806Inherited
    50156,52540,51045
  • 50156 - PDZ domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 51045 - WW domain
  • 0.004373Inherited
    51045,51045,50156
  • 51045 - WW domain
  • 51045 - WW domain
  • 50156 - PDZ domain-like
  • 0.008814Inherited
    57424,57196,57196
  • 57424 - LDL receptor-like module
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.1227Inherited
    49562,57889,57889
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 57889 - Cysteine-rich domain
  • 57889 - Cysteine-rich domain
  • 1Inherited
    50044,50044,50044
  • 50044 - SH3-domain
  • 50044 - SH3-domain
  • 50044 - SH3-domain
  • 0.2348Inherited
    57424,57424,57424
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 0.197Inherited
    49562,49562,49562
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 0.01002Inherited
    57424,57184,63825
  • 57424 - LDL receptor-like module
  • 57184 - Growth factor receptor domain
  • 63825 - YWTD domain
  • 0.008058Inherited
    57424,57424,57184
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 57184 - Growth factor receptor domain
  • 0.01198Inherited
    63825,57196,63825
  • 63825 - YWTD domain
  • 57196 - EGF/Laminin
  • 63825 - YWTD domain
  • 0.1507Inherited
    100895,47473,57610
  • 100895 - Kazal-type serine protease inhibitors
  • 47473 - EF-hand
  • 57610 - Thyroglobulin type-1 domain
  • 0.0131Inherited
    51045,51045,56204
  • 51045 - WW domain
  • 51045 - WW domain
  • 56204 - Hect, E3 ligase catalytic domain
  • 0.03831Inherited
    57184,57184,57196
  • 57184 - Growth factor receptor domain
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 0.02641Inherited
    57196,57196,90193
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 90193 - Notch domain
  • 0.008351Inherited
    57196,90193,90193
  • 57196 - EGF/Laminin
  • 90193 - Notch domain
  • 90193 - Notch domain
  • 0.005334Inherited
    90193,90193,90193
  • 90193 - Notch domain
  • 90193 - Notch domain
  • 90193 - Notch domain
  • 0.008351Inherited
    57184,57196,57196
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.004604Inherited
    57196,57184,57184
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 57184 - Growth factor receptor domain
  • 0.006299Inherited
    49562,48371,56112
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 48371 - ARM repeat
  • 56112 - Protein kinase-like (PK-like)
  • 1Inherited
    46966,46966,47473
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 47473 - EF-hand
  • 0.6169Inherited
    57184,52058,57184
  • 57184 - Growth factor receptor domain
  • 52058 - L domain-like
  • 57184 - Growth factor receptor domain
  • 0.1008Inherited
    47459,55785,55785
  • 47459 - HLH, helix-loop-helix DNA-binding domain
  • 55785 - PYP-like sensor domain (PAS domain)
  • 55785 - PYP-like sensor domain (PAS domain)
  • 0.3961Inherited
    49313,49313,49313
  • 49313 - Cadherin-like
  • 49313 - Cadherin-like
  • 49313 - Cadherin-like
  • 0.1035Inherited
    57716,57716,57716
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 0.9059Inherited
    46966,46966,46966
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 0.4972Inherited
    57196,57196,69687
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 69687 - Integrin beta tail domain
  • 1Inherited
    57603,57603,57603
  • 57603 - FnI-like domain
  • 57603 - FnI-like domain
  • 57603 - FnI-like domain
  • 0.1008Inherited
    57184,57196,57184
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 0.0131Inherited
    54791,54791,54791
  • 54791 - Eukaryotic type KH-domain (KH-domain type I)
  • 54791 - Eukaryotic type KH-domain (KH-domain type I)
  • 54791 - Eukaryotic type KH-domain (KH-domain type I)
  • 0.4475Inherited
    48452,81901,48452
  • 48452 - TPR-like
  • 81901 - HCP-like
  • 48452 - TPR-like
  • 0.002434Inherited
    81901,48452,48452
  • 81901 - HCP-like
  • 48452 - TPR-like
  • 48452 - TPR-like
  • 0.003312Inherited
    53067,53067,100920
  • 53067 - Actin-like ATPase domain
  • 53067 - Actin-like ATPase domain
  • 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
  • 0.5732Inherited
    57630,57196,57196
  • 57630 - GLA-domain
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.0786Inherited
    57196,57196,50494
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 50494 - Trypsin-like serine proteases
  • 0.0786Inherited
    50729,47473,51695
  • 50729 - PH domain-like
  • 47473 - EF-hand
  • 51695 - PLC-like phosphodiesterases
  • 0.1985Inherited
    57184,57581,57196
  • 57184 - Growth factor receptor domain
  • 57581 - TB module/8-cys domain
  • 57196 - EGF/Laminin
  • 0.1663Inherited
    57581,57196,57196
  • 57581 - TB module/8-cys domain
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.2505Inherited
    57581,57196,57581
  • 57581 - TB module/8-cys domain
  • 57196 - EGF/Laminin
  • 57581 - TB module/8-cys domain
  • 0.3306Inherited
    47769,47769,47769
  • 47769 - SAM/Pointed domain
  • 47769 - SAM/Pointed domain
  • 47769 - SAM/Pointed domain
  • 0.02506Inherited
    49854,57535,57535
  • 49854 - Spermadhesin, CUB domain
  • 57535 - Complement control module/SCR domain
  • 57535 - Complement control module/SCR domain
  • 0.04532Inherited
    57196,57196,50242
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 50242 - TIMP-like
  • 0.00217Inherited
    57535,49854,57535
  • 57535 - Complement control module/SCR domain
  • 49854 - Spermadhesin, CUB domain
  • 57535 - Complement control module/SCR domain
  • 0.001175Inherited
    49854,57535,49854
  • 49854 - Spermadhesin, CUB domain
  • 57535 - Complement control module/SCR domain
  • 49854 - Spermadhesin, CUB domain
  • 0.003312Inherited
    57424,57424,57196
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 57196 - EGF/Laminin
  • 0.1166Inherited
    49899,49899,49899
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.001407Inherited
    47473,47473,47473
  • 47473 - EF-hand
  • 47473 - EF-hand
  • 47473 - EF-hand
  • 0.001345Inherited
    101288,50156,50044
  • 101288 - L27 domain
  • 50156 - PDZ domain-like
  • 50044 - SH3-domain
  • 0.001695Inherited
    50156,50729,50729
  • 50156 - PDZ domain-like
  • 50729 - PH domain-like
  • 50729 - PH domain-like
  • 0.1227Inherited
    54160,52540,52540
  • 54160 - Chromo domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.0131Inherited
    54160,54160,52540
  • 54160 - Chromo domain-like
  • 54160 - Chromo domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.0131Inherited
    74788,75632,46785
  • 74788 - Cullin repeat-like
  • 75632 - Cullin homology domain
  • 46785 - "Winged helix" DNA-binding domain
  • 0.1166Inherited


    Plot distribution on phylogenetic tree for Individual Supra-domains annotated by this GO term
    Plot tree as:   Download Newick format tree:   Browsing in Tree_gateway:
    (show help)