SUPERFAMILY 1.75 HMM library and genome assignments server

Metallo-dependent hydrolases superfamily models

A superfamily is represented by one or more models; usually there is more than one model representing the superfamily. Since each model is built to capture the whole superfamily, they are likely to be overlapping and sometimes are mostly overlapping or even redundant to each other. Also models often do not score their own seed sequence more highly than other sequences in the superfamily, so it is a mistake to think that the model represents the seed sequence.

All models are available for immediate download after obtaining a license by filling in a short online registration form. Licenses are free for academic and commercial purposes.

Plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be viewed for each model by following the model ID link.


All 52 SUPERFAMILY models representing the Metallo-dependent hydrolases superfamily
Model ID No. of seqs Build date Seed sequence Family of seed
0051799 3119 2008-09-10 d2amxa1 Adenosine/AMP deaminase
0047865 2007 2008-09-10 d1krma_ Adenosine/AMP deaminase
0051697 1825 2008-09-10 d2a3la1 Adenosine/AMP deaminase
0045709 1895 2008-09-10 d1a4ma_ Adenosine/AMP deaminase
0046571 259 2008-09-10 d1ejrc2 alpha-subunit of urease, catalytic domain
0045611 48 2005-09-08 d4ubpc2 alpha-subunit of urease, catalytic domain
0036862 127 2005-09-08 d1e9yb2 alpha-subunit of urease, catalytic domain
0037271 86 2005-09-08 d1eywa_ Phosphotriesterase-like
0045950 398 2008-09-10 d1bf6a_ Phosphotriesterase-like
0052371 154 2008-09-10 d2d2ja1 Phosphotriesterase-like
0047525 211 2008-09-10 d1j79a_ Dihydroorotase
0039934 78 2005-09-08 d1k6wa2 Cytosine deaminase catalytic domain
0052760 1760 2008-09-10 d2ftwa2 Hydantoinase (dihydropyrimidinase), catalytic domain
0038137 33 2005-09-08 d1gkpa2 Hydantoinase (dihydropyrimidinase), catalytic domain
0039842 502 2005-09-08 d1k1da2 Hydantoinase (dihydropyrimidinase), catalytic domain
0048352 894 2008-09-10 d1nfga2 Hydantoinase (dihydropyrimidinase), catalytic domain
0052789 1927 2008-09-10 d2fvka2 Hydantoinase (dihydropyrimidinase), catalytic domain
0051353 896 2008-09-10 d1ynya2 Hydantoinase (dihydropyrimidinase), catalytic domain
0047785 2227 2008-09-10 d1kcxa2 Hydantoinase (dihydropyrimidinase), catalytic domain
0047006 2307 2008-09-10 d1gkra2 Hydantoinase (dihydropyrimidinase), catalytic domain
0051086 1263 2008-09-10 d1xrta2 Hydantoinase (dihydropyrimidinase), catalytic domain
0047434 958 2008-09-10 d1itua_ Renal dipeptidase
0054604 79 2010-05-31 d2qeec1 Uronate isomerase-like
0047517 239 2008-09-10 d1j5sa_ Uronate isomerase-like
0054688 1807 2010-05-31 d2uz9a2 SAH/MTA deaminase-like
0047519 1843 2008-09-10 d1j6pa2 SAH/MTA deaminase-like
0054113 1903 2010-05-31 d2i9ua2 SAH/MTA deaminase-like
0054394 1600 2010-05-31 d2ooda2 SAH/MTA deaminase-like
0054489 1929 2010-05-31 d2paja2 SAH/MTA deaminase-like
0048480 551 2008-09-10 d1o12a2 N-acetylglucosamine-6-phosphate deacetylase, NagA, catalytic domain
0051379 447 2008-09-10 d1yrra2 N-acetylglucosamine-6-phosphate deacetylase, NagA, catalytic domain
0049957 371 2008-09-10 d1un7a2 N-acetylglucosamine-6-phosphate deacetylase, NagA, catalytic domain
0048115 1546 2008-09-10 d1m7ja3 D-aminoacylase, catalytic domain
0051322 1622 2008-09-10 d1yixa1 TatD Mg-dependent DNase-like
0051135 1815 2008-09-10 d1xwya1 TatD Mg-dependent DNase-like
0039386 524 2005-09-08 d1j6oa_ TatD Mg-dependent DNase-like
0051670 1309 2008-09-10 d1zzma1 TatD Mg-dependent DNase-like
0048612 236 2008-09-10 d1onwa2 Isoaspartyl dipeptidase, catalytic domain
0053093 192 2008-09-10 d2icsa2 Adenine deaminase-like
0052968 744 2008-09-10 d2gwga1 PP1699/LP2961-like
0052488 991 2008-09-10 d2dvta1 PP1699/LP2961-like
0052675 428 2008-09-10 d2ffia1 PP1699/LP2961-like
0053002 1981 2008-09-10 d2hbva1 PP1699/LP2961-like
0052605 397 2008-09-10 d2f6ka1 PP1699/LP2961-like
0054148 1831 2010-05-31 d2imra2 DR0824-like
0054568 1808 2010-05-31 d2q09a2 Imidazolonepropionase-like
0054484 1424 2010-05-31 d2p9ba2 Imidazolonepropionase-like
0054549 1588 2010-05-31 d2puza2 Imidazolonepropionase-like
0053742 1597 2010-05-31 d2bb0a2 Imidazolonepropionase-like
0054826 500 2010-05-31 d3be7a2 Zn-dependent arginine carboxypeptidase-like
0054628 500 2010-05-31 d2qs8a2 Zn-dependent arginine carboxypeptidase-like
0054658 1407 2010-05-31 d2r8ca2 Zn-dependent arginine carboxypeptidase-like