SUPERFAMILY 1.75 HMM library and genome assignments server

ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase superfamily models

A superfamily is represented by one or more models; usually there is more than one model representing the superfamily. Since each model is built to capture the whole superfamily, they are likely to be overlapping and sometimes are mostly overlapping or even redundant to each other. Also models often do not score their own seed sequence more highly than other sequences in the superfamily, so it is a mistake to think that the model represents the seed sequence.

All models are available for immediate download after obtaining a license by filling in a short online registration form. Licenses are free for academic and commercial purposes.

Plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be viewed for each model by following the model ID link.


All 23 SUPERFAMILY models representing the ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase superfamily
Model ID No. of seqs Build date Seed sequence Family of seed
0053133 2765 2008-09-10 d2iwxa1 Heat shock protein 90, HSP90, N-terminal domain
0044566 789 2005-09-08 d1uyma_ Heat shock protein 90, HSP90, N-terminal domain
0043038 265 2005-09-08 d1qy5a_ Heat shock protein 90, HSP90, N-terminal domain
0043939 1101 2005-09-08 d1tc6a_ Heat shock protein 90, HSP90, N-terminal domain
0035784 865 2005-09-08 d1byqa_ Heat shock protein 90, HSP90, N-terminal domain
0035364 1659 2005-09-08 d1b63a2 DNA gyrase/MutL, N-terminal domain
0048223 3890 2008-09-10 d1mu5a3 DNA gyrase/MutL, N-terminal domain
0043462 1195 2005-09-08 d1s14a_ DNA gyrase/MutL, N-terminal domain
0040105 2202 2005-09-08 d1kija2 DNA gyrase/MutL, N-terminal domain
0037015 1555 2005-09-08 d1ei1a2 DNA gyrase/MutL, N-terminal domain
0042491 1168 2005-09-08 d1pvga2 DNA gyrase/MutL, N-terminal domain
0038465 1263 2005-09-08 d1h7sa2 DNA gyrase/MutL, N-terminal domain
0043464 1301 2005-09-08 d1s16a2 DNA gyrase/MutL, N-terminal domain
0038974 5219 2005-09-08 d1id0a_ Histidine kinase
0052097 27728 2008-09-10 d2c2aa2 Histidine kinase
0035339 5242 2005-09-08 d1b3qa3 Histidine kinase
0046033 14902 2008-09-10 d1bxda_ Histidine kinase
0043142 5874 2005-09-08 d1r62a_ Histidine kinase
0051393 17801 2008-09-10 d1ysra1 Histidine kinase
0040344 3874 2005-09-08 d1l0oa_ Histidine kinase
0038146 3500 2005-09-08 d1gkza2 alpha-ketoacid dehydrogenase kinase, C-terminal domain
0053651 2025 2010-05-31 d1y8oa2 alpha-ketoacid dehydrogenase kinase, C-terminal domain
0039624 3816 2005-09-08 d1jm6a2 alpha-ketoacid dehydrogenase kinase, C-terminal domain