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Disease Ontology (DO): respiratory system cancer

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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Root: DO Hierarchy (disease ontology from University of Maryland)

Shortest distance to current term (+ for parents, - for children) DO term [DO ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + 4:   disease [DOID:4] <8>
+ + + 3:   disease of cellular proliferation [DOID:14566] <3>(123|191) (129|118|56)
+ + 2:   cancer [DOID:162] <2>(115|181) (120|113|54)
+ 1:   organ system cancer [DOID:0050686] <14>(66|106) (72|58|31)
0:   respiratory system cancer [DOID:0050615] <6>(8|12) (9|7|2)
- 1:   lung cancer [DOID:1324] <10>(6|10) (7|6|2)
- 1:   larynx cancer [DOID:2596] <6>(4|4) (4|2|0)
- 1:   paranasal sinus cancer [DOID:0050619] <6>(0|0) (0|0|0)
- 1:   nasal cavity cancer [DOID:10811] <3>(0|0) (0|0|0)
- 1:   tracheal cancer [DOID:11920] <3>(0|0) (0|0|0)
- 1:   bronchus cancer [DOID:1325] <2>(0|0) (0|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
p53 tetramerization domain0Direct
DNA clamp0Direct
Kringle-like0.003013Inherited
Cyclin-like0.007272Inherited
Protein kinase-like (PK-like)0.008361Inherited
Intermediate filament protein, coiled coil region0.06571Inherited
p53-like transcription factors0.1016Inherited
Prefoldin0.1256Inherited


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

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SCOP termFDR (all)Annotation (direct or inherited)
p53 DNA-binding domain-like0Direct
p53 tetramerization domain0Direct
S100 proteins0.0005515Direct
L domain0.003834Inherited
DEATH effector domain, DED0.004267Inherited
Platelet-derived growth factor-like0.009236Inherited
Extracellular domain of cell surface receptors0.009236Inherited
Protein kinases, catalytic subunit0.01711Inherited
Fibronectin type II module0.01763Inherited
Growth factor receptor domain0.03732Inherited
Cyclin0.0545Inherited
Intermediate filament protein, coiled coil region0.05839Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
Plot tree as:   Download Newick format tree:
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
p53 tetramerization domain0Direct
DNA clamp0Direct
Kringle-like0.001996Inherited
Cyclin-like0.004997Inherited
Protein kinase-like (PK-like)0.005744Inherited
Intermediate filament protein, coiled coil region0.05079Inherited
4-helical cytokines0.06943Inherited
p53-like transcription factors0.08087Inherited
Prefoldin0.1007Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
49417,47719
  • 49417 - p53-like transcription factors
  • 47719 - p53 tetramerization domain
  • 0Direct
    57440,57440
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 0.002368Inherited
    57184,52058
  • 57184 - Growth factor receptor domain
  • 52058 - L domain-like
  • 0.003367Inherited
    52058,57184
  • 52058 - L domain-like
  • 57184 - Growth factor receptor domain
  • 0.003367Inherited
    47954,47954
  • 47954 - Cyclin-like
  • 47954 - Cyclin-like
  • 0.005611Inherited
    57184,57603
  • 57184 - Growth factor receptor domain
  • 57603 - FnI-like domain
  • 0.01229Inherited
    46579,64593
  • 46579 - Prefoldin
  • 64593 - Intermediate filament protein, coiled coil region
  • 0.02608Inherited

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    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    52058,57184,52058
  • 52058 - L domain-like
  • 57184 - Growth factor receptor domain
  • 52058 - L domain-like
  • 0.003367Inherited
    57184,52058,57184
  • 57184 - Growth factor receptor domain
  • 52058 - L domain-like
  • 57184 - Growth factor receptor domain
  • 0.003845Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
    (show help)