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Disease Ontology (DO): benign neoplasm

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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Root: DO Hierarchy (disease ontology from University of Maryland)

Shortest distance to current term (+ for parents, - for children) DO term [DO ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + 2:   disease [DOID:4] <8>
+ 1:   disease of cellular proliferation [DOID:14566] <3>(123|191) (129|118|56)
0:   benign neoplasm [DOID:0060072] <2>(14|21) (16|14|9)
- 1:   cell type benign neoplasm [DOID:0060084] <18>(9|15) (11|13|8)
- 1:   organ system benign neoplasm [DOID:0060085] <12>(7|9) (7|4|5)


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
p53 tetramerization domain0Direct
Cystine-knot cytokines0.00000002116Direct
Notch domain0.0000553Direct
Lipoxigenase0.000288Direct
Heme-dependent peroxidases0.001412Inherited
Serine protease inhibitors0.001782Inherited
Nuclear receptor ligand-binding domain0.003797Inherited
Family A G protein-coupled receptor-like0.006128Inherited
PGBD-like0.007823Inherited
Ankyrin repeat0.02096Inherited
Inhibitor of apoptosis (IAP) repeat0.02195Inherited
p53-like transcription factors0.0246Inherited
SNARE fusion complex0.0422Inherited
Growth factor receptor domain0.1203Inherited


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Family

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SCOP termFDR (all)Annotation (direct or inherited)
DEATH effector domain, DED0Direct
p53 tetramerization domain0Direct
p53 DNA-binding domain-like0Direct
Transforming growth factor (TGF)-beta0.00002999Direct
Platelet-derived growth factor-like0.00003174Direct
Notch domain0.00004391Direct
Animal lipoxigenases0.0002235Direct
Myeloperoxidase-like0.001141Inherited
Lipoxigenase N-terminal domain0.001376Inherited
Glutathione peroxidase-like0.00236Inherited
Nuclear receptor ligand-binding domain0.003733Inherited
Rhodopsin-like0.003818Inherited
Nuclear receptor0.006763Inherited
MMP N-terminal domain0.006781Inherited
Ankyrin repeat0.01636Inherited
Inhibitor of apoptosis (IAP) repeat0.01851Inherited
S100 proteins0.02055Inherited
Rel/Dorsal transcription factors, DNA-binding domain0.02957Inherited
SNARE fusion complex0.03736Inherited
NF-kappa-B/REL/DORSAL transcription factors, C-terminal domain0.06045Inherited
Growth factor receptor domain0.06108Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
p53 tetramerization domain0Direct
Cystine-knot cytokines0.00000001008Direct
Notch domain0.00003196Direct
Lipoxigenase0.0001743Direct
Heme-dependent peroxidases0.0008992Direct
Putative DNA-binding domain0.001147Inherited
Serine protease inhibitors0.001147Inherited
Nuclear receptor ligand-binding domain0.002546Inherited
Family A G protein-coupled receptor-like0.004198Inherited
PGBD-like0.005389Inherited
Thioredoxin-like0.01405Inherited
Ankyrin repeat0.0152Inherited
Inhibitor of apoptosis (IAP) repeat0.01598Inherited
p53-like transcription factors0.01802Inherited
SNARE fusion complex0.03178Inherited
Growth factor receptor domain0.09637Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
49417,47719
  • 49417 - p53-like transcription factors
  • 47719 - p53 tetramerization domain
  • 0Direct
    90193,90193
  • 90193 - Notch domain
  • 90193 - Notch domain
  • 0Direct
    57196,90193
  • 57196 - EGF/Laminin
  • 90193 - Notch domain
  • 0Direct
    63501,50242
  • 63501 - Frizzled cysteine-rich domain
  • 50242 - TIMP-like
  • 0.0001743Direct
    49723,48484
  • 49723 - Lipase/lipooxygenase domain (PLAT/LH2 domain)
  • 48484 - Lipoxigenase
  • 0.0001743Direct
    103575,81296
  • 103575 - Plexin repeat
  • 81296 - E set domains
  • 0.0002982Direct
    48726,56436
  • 48726 - Immunoglobulin
  • 56436 - C-type lectin-like
  • 0.00401Inherited
    57924,57924
  • 57924 - Inhibitor of apoptosis (IAP) repeat
  • 57924 - Inhibitor of apoptosis (IAP) repeat
  • 0.00401Inherited
    47090,55486
  • 47090 - PGBD-like
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 0.005389Inherited
    57440,57440
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 0.007268Inherited
    57716,48508
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 48508 - Nuclear receptor ligand-binding domain
  • 0.007379Inherited
    57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.008017Inherited
    57196,57184
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 0.01526Inherited
    49417,81296
  • 49417 - p53-like transcription factors
  • 81296 - E set domains
  • 0.02568Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    57196,57196,90193
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 90193 - Notch domain
  • 0Direct
    47986,47986,52129
  • 47986 - DEATH domain
  • 47986 - DEATH domain
  • 52129 - Caspase-like
  • 0Direct
    103575,81296,81296
  • 103575 - Plexin repeat
  • 81296 - E set domains
  • 81296 - E set domains
  • 0.0002982Direct
    48726,56436,56436
  • 48726 - Immunoglobulin
  • 56436 - C-type lectin-like
  • 56436 - C-type lectin-like
  • 0.00401Inherited
    57184,57196,57184
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 0.00401Inherited
    57196,57184,57184
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 57184 - Growth factor receptor domain
  • 0.004156Inherited
    57196,57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.005692Inherited
    57440,57440,57440
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 0.0089Inherited
    57196,57196,57184
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 0.0173Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
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