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Disease Ontology (DO): myeloid neoplasm

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Root: DO Hierarchy (disease ontology from University of Maryland)

Shortest distance to current term (+ for parents, - for children) DO term [DO ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + + + + 7:   disease [DOID:4] <8>
+ + + + + + 6:   disease of cellular proliferation [DOID:14566] <3>(123|191) (129|118|56)
+ + + + + 5:   cancer [DOID:162] <2>(115|181) (120|113|54)
+ + + + 4:   organ system cancer [DOID:0050686] <14>(66|106) (72|58|31)
+ + + 3:   immune system cancer [DOID:0060083] <3>(31|42) (33|27|13)
+ + 2:   hematologic cancer [DOID:2531] <7>(30|42) (32|25|13)
+ 1:   bone marrow cancer [DOID:4960] <2>(10|13) (10|8|6)
0:   myeloid neoplasm [DOID:0070004] <5>(10|13) (10|7|4)
- 1:   multiple myeloma [DOID:9538] <5>(2|5) (2|2|1)
- 1:   myeloid and lymphoid neoplasms with eosinophilia and abnormalities of PDGFRA, PDGFRB, and FGFR1 [DOID:0080164] <3>(0|0) (0|0|0)
- 1:   myelodysplastic/myeloproliferative neoplasm [DOID:4972] <2>(1|1) (1|0|0)
- 1:   myeloproliferative neoplasm [DOID:2226] <2>(0|0) (0|0|0)
- 1:   myelofibrosis [DOID:4971] <1>(1|0) (1|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
TNF receptor-like0.000001666Direct
TNF-like0.00002687Direct
4-helical cytokines0.0001068Direct
TIMP-like0.0001382Direct
PGBD-like0.0002053Direct
Frizzled cysteine-rich domain0.0002053Direct
Hemopexin-like domain0.0008098Direct
Cystine-knot cytokines0.003336Inherited
Integrin domains0.004564Inherited
SH2 domain1Inherited


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

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SCOP termFDR (all)Annotation (direct or inherited)
BAFF receptor-like0Direct
TNF-like0.00002312Direct
DEATH effector domain, DED0.00009433Direct
Frizzled cysteine-rich domain0.000163Direct
MMP N-terminal domain0.000163Direct
Short-chain cytokines0.0002825Direct
TNF receptor-like0.0003402Direct
Matrix metalloproteases, catalytic domain0.000473Direct
Hemopexin-like domain0.0006438Direct
Fibronectin type II module0.0007153Direct
Interleukin-1 (IL-1)0.00288Inherited
Integrin domains0.003709Inherited
SH2 domain1Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
TNF receptor-like0.0000008703Direct
TNF-like0.00001524Direct
4-helical cytokines0.00006286Direct
TIMP-like0.00008226Direct
Frizzled cysteine-rich domain0.0001231Direct
PGBD-like0.0001231Direct
Hemopexin-like domain0.0005029Direct
Cystine-knot cytokines0.002221Inherited
Integrin domains0.003083Inherited
SH2 domain0.974Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
63501,50242
  • 63501 - Frizzled cysteine-rich domain
  • 50242 - TIMP-like
  • 0Direct
    57586,57586
  • 57586 - TNF receptor-like
  • 57586 - TNF receptor-like
  • 0.00001871Direct
    57196,57424
  • 57196 - EGF/Laminin
  • 57424 - LDL receptor-like module
  • 0.00007672Direct
    47986,47986
  • 47986 - DEATH domain
  • 47986 - DEATH domain
  • 0.00007719Direct
    47090,55486
  • 47090 - PGBD-like
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 0.0001231Direct
    57440,57440
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 0.0003397Direct
    63825,57196
  • 63825 - YWTD domain
  • 57196 - EGF/Laminin
  • 0.0007524Direct

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    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    47986,47986,52129
  • 47986 - DEATH domain
  • 47986 - DEATH domain
  • 52129 - Caspase-like
  • 0Direct
    63825,57196,57424
  • 63825 - YWTD domain
  • 57196 - EGF/Laminin
  • 57424 - LDL receptor-like module
  • 0.00007672Direct
    57196,57424,57424
  • 57196 - EGF/Laminin
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 0.00007672Direct
    57440,57440,57440
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 0.0007524Direct


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
    (show help)