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Disease Ontology (DO): blood coagulation disease

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Root: DO Hierarchy (disease ontology from University of Maryland)

Shortest distance to current term (+ for parents, - for children) DO term [DO ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + 3:   disease [DOID:4] <8>
+ + 2:   disease of anatomical entity [DOID:7] <12>(143|187) (147|103|58)
+ 1:   hematopoietic system disease [DOID:74] <7>(27|29) (27|15|8)
0:   blood coagulation disease [DOID:1247] <4>(16|18) (17|10|6)
- 1:   inherited blood coagulation disease [DOID:2214] <27>(6|6) (6|1|0)
- 1:   hemorrhagic disease [DOID:2213] <4>(8|10) (9|6|4)
- 1:   thrombophilia [DOID:2452] <3>(2|1) (2|0|1)
- 1:   coagulation protein disease [DOID:2212](0|0) (0|0|0)


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
Fibrinogen coiled-coil and central regions0Direct
GLA-domain0.0000000002508Direct
EGF/Laminin0.000003213Direct
Hairpin loop containing domain-like0.000009339Direct
Notch domain0.0000382Direct
Integrin domains0.00148Inherited
Cupredoxins0.001678Inherited
Fibrinogen C-terminal domain-like0.002501Inherited
Cytokine0.002946Inherited
Serpins0.002946Inherited
TNF-like0.004405Inherited
Trypsin-like serine proteases0.02207Inherited
vWA-like0.1053Inherited
4-helical cytokines0.2462Inherited
L domain-like0.4155Inherited
MHC antigen-recognition domain0.4868Inherited


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

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SCOP termFDR (all)Annotation (direct or inherited)
Fibrinogen coiled-coil and central regions0Direct
Multidomain cupredoxins0Direct
GLA-domain0.0000000002668Direct
Notch domain0.00003269Direct
EGF-type module0.0001007Direct
Kringle modules0.0002161Direct
Interleukin-1 (IL-1)0.0002962Direct
Integrin domains0.00136Inherited
Fibrinogen C-terminal domain-like0.002353Inherited
Serpins0.002353Inherited
TNF-like0.004181Inherited
Eukaryotic proteases0.02422Inherited
Integrin A (or I) domain0.03443Inherited
Ngr ectodomain-like0.3111Inherited
C1 set domains (antibody constant domain-like)0.5004Inherited
MHC antigen-recognition domain0.5004Inherited
Short-chain cytokines0.5306Inherited
Complement control module/SCR domain0.5313Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Fibrinogen coiled-coil and central regions0Direct
GLA-domain0.0000000001164Direct
EGF/Laminin0.000001712Direct
Hairpin loop containing domain-like0.000005144Direct
Notch domain0.00002182Direct
Integrin domains0.0009459Direct
Cupredoxins0.001076Inherited
Fibrinogen C-terminal domain-like0.001649Inherited
Serpins0.001945Inherited
Cytokine0.001945Inherited
TNF-like0.002964Inherited
Trypsin-like serine proteases0.01606Inherited
vWA-like0.08389Inherited
4-helical cytokines0.206Inherited
L domain-like0.3603Inherited
MHC antigen-recognition domain0.427Inherited
Complement control module/SCR domain0.4475Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
57196,50494
  • 57196 - EGF/Laminin
  • 50494 - Trypsin-like serine proteases
  • 0Direct
    49503,49503
  • 49503 - Cupredoxins
  • 49503 - Cupredoxins
  • 0Direct
    57196,90193
  • 57196 - EGF/Laminin
  • 90193 - Notch domain
  • 0Direct
    57630,57196
  • 57630 - GLA-domain
  • 57196 - EGF/Laminin
  • 0.000000004247Direct
    57440,50494
  • 57440 - Kringle-like
  • 50494 - Trypsin-like serine proteases
  • 0.00001342Direct
    57196,57184
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 0.0009459Direct
    57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.0009963Direct
    57184,57184
  • 57184 - Growth factor receptor domain
  • 57184 - Growth factor receptor domain
  • 0.003633Inherited
    55550,56112
  • 55550 - SH2 domain
  • 56112 - Protein kinase-like (PK-like)
  • 0.01209Inherited
    54452,48726
  • 54452 - MHC antigen-recognition domain
  • 48726 - Immunoglobulin
  • 0.427Inherited

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    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    57630,57196,50494
  • 57630 - GLA-domain
  • 57196 - EGF/Laminin
  • 50494 - Trypsin-like serine proteases
  • 0Direct
    57196,57196,90193
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 90193 - Notch domain
  • 0Direct
    57440,57440,50494
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 50494 - Trypsin-like serine proteases
  • 0.00005748Direct
    57196,57196,57184
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 0.0001977Direct
    57196,57184,57184
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 57184 - Growth factor receptor domain
  • 0.0003472Direct
    57196,57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.0007238Direct


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
    (show help)