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Disease Ontology (DO): endocrine system disease

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Root: DO Hierarchy (disease ontology from University of Maryland)

Shortest distance to current term (+ for parents, - for children) DO term [DO ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + 2:   disease [DOID:4] <8>
+ 1:   disease of anatomical entity [DOID:7] <12>(143|187) (147|103|58)
0:   endocrine system disease [DOID:28] <7>(14|16) (15|4|1)
- 1:   thyroid gland disease [DOID:50] <10>(4|3) (4|1|0)
- 1:   pancreas disease [DOID:26] <8>(6|7) (6|1|1)
- 1:   pituitary gland disease [DOID:53] <6>(1|1) (1|0|0)
- 1:   adrenal gland disease [DOID:9553] <5>(1|1) (1|0|0)
- 1:   gonadal disease [DOID:2277] <3>(2|3) (3|1|0)
- 1:   cortisone reductase deficiency [DOID:0090139] <2>(0|0) (0|0|0)
- 1:   parathyroid gland disease [DOID:11201] <2>(0|0) (0|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
Heme-dependent peroxidases0.000166Direct
Insulin-like0.0003831Direct
TNF receptor-like0.0006238Direct
Nuclear receptor ligand-binding domain0.001336Inherited
GLA-domain0.006293Inherited
MHC antigen-recognition domain0.006504Inherited
Riboflavin synthase domain-like0.01808Inherited
Ferredoxin reductase-like, C-terminal NADP-linked domain0.01808Inherited
TNF-like0.02547Inherited
Cytochrome P4500.02752Inherited
Lipase/lipooxygenase domain (PLAT/LH2 domain)0.03292Inherited
Thyroglobulin type-1 domain0.03292Inherited
MFS general substrate transporter0.3352Inherited
Homeodomain-like0.6967Inherited


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Family

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SCOP termFDR (all)Annotation (direct or inherited)
Myeloperoxidase-like0.0001297Direct
TNF receptor-like0.0001552Direct
Insulin-like0.0002908Direct
Nuclear receptor ligand-binding domain0.001197Inherited
Pancreatic lipase, N-terminal domain0.001894Inherited
Nuclear receptor0.002706Inherited
GLA-domain0.005039Inherited
MHC antigen-recognition domain0.00559Inherited
C1 set domains (antibody constant domain-like)0.007011Inherited
Phosphotyrosine-binding domain (PTB)0.01999Inherited
TNF-like0.02264Inherited
Thyroglobulin type-1 domain0.02782Inherited
Cytochrome P4500.05689Inherited
Transforming growth factor (TGF)-beta0.1103Inherited
EGF-type module0.2541Inherited
Homeodomain0.6633Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Heme-dependent peroxidases0.00009916Direct
Insulin-like0.0002333Direct
TNF receptor-like0.0003836Direct
Nuclear receptor ligand-binding domain0.0008501Direct
GLA-domain0.004306Inherited
MHC antigen-recognition domain0.004458Inherited
Riboflavin synthase domain-like0.013Inherited
Ferredoxin reductase-like, C-terminal NADP-linked domain0.013Inherited
Cystine-knot cytokines0.01596Inherited
TNF-like0.01869Inherited
Cytochrome P4500.02027Inherited
Lipase/lipooxygenase domain (PLAT/LH2 domain)0.02458Inherited
Thyroglobulin type-1 domain0.02458Inherited
MFS general substrate transporter0.2879Inherited
Homeodomain-like0.6253Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
57586,57586
  • 57586 - TNF receptor-like
  • 57586 - TNF receptor-like
  • 0.0000672Direct
    53474,49723
  • 53474 - alpha/beta-Hydrolases
  • 49723 - Lipase/lipooxygenase domain (PLAT/LH2 domain)
  • 0.0004405Direct
    54452,48726
  • 54452 - MHC antigen-recognition domain
  • 48726 - Immunoglobulin
  • 0.003483Inherited
    50729,50729
  • 50729 - PH domain-like
  • 50729 - PH domain-like
  • 0.03021Inherited

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    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    57586,57586,57586
  • 57586 - TNF receptor-like
  • 57586 - TNF receptor-like
  • 57586 - TNF receptor-like
  • 0.00009916Direct


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
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