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Enzyme Commission (EC): Acyltransferases

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Root: EC Hierarchy (from IntEnz release 70)

Shortest distance to current term (+ for parents, - for children) EC term [EC ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + 2:   root [root] <7>
+ 1:   Transferases [2] <10>(447|679) (446|546|277)
0:   Acyltransferases [2.3] <3>(128|153) (128|117|43)
- 1:   Transferring groups other than amino-acyl groups [2.3.1] <285>(67|78) (67|46|17)
- 1:   Aminoacyltransferases [2.3.2] <32>(61|68) (61|65|22)
- 1:   Acyl groups converted into alkyl groups on transfer [2.3.3] <20>(13|14) (13|9|4)


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Superfamily

(show details)
SCOP termFDR (all)Annotation (direct or inherited)
HLH, helix-loop-helix DNA-binding domain0Direct
DmpA/ArgJ-like0Direct
CCCH zinc finger0Direct
PA domain0Direct
Glycerol-3-phosphate (1)-acyltransferase0Direct
NRDP1 C-terminal domain-like0Direct
PABC (PABP) domain0Direct
Probable ACP-binding domain of malonyl-CoA ACP transacylase0Direct
N-terminal domain of cbl (N-cbl)0Direct
UBC-like0Direct
Trimeric LpxA-like enzymes0Direct
CHY zinc finger-like0Direct
Leucine zipper domain0Direct
WW domain0Direct
TRAF domain-like0Direct
Trimerization domain of TRAF0Direct
TAZ domain0Direct
Actin-like ATPase domain0Direct
Concanavalin A-like lectins/glucanases0Direct
Isocitrate/Isopropylmalate dehydrogenase-like0Direct
post-HMGL domain-like0Direct
HprK N-terminal domain-like0Direct
Zinc hairpin stack0Direct
CoA-dependent acyltransferases0Direct
Hect, E3 ligase catalytic domain0Direct
SWIB/MDM2 domain0Direct
ACP-like0Direct
Transglutaminase, two C-terminal domains0Direct
ClpS-like0Direct
Bromodomain0Direct
2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain0Direct
Mib/herc2 domain-like0Direct
Aldolase0Direct
Formylmethanofuran:tetrahydromethanopterin formyltransferase0Direct
RING/U-box0Direct
Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex0Direct
FabD/lysophospholipase-like0Direct
Acyl-CoA N-acyltransferases (Nat)0Direct
Thiolase-like0Direct
Single hybrid motif0Direct
Nucleotide-diphospho-sugar transferases0Direct
NHL repeat0Direct
CCHHC domain0Direct
Nuclear receptor coactivator interlocking domain0Direct
FYVE/PHD zinc finger0Direct
Citrate synthase0Direct
Malate synthase G0Direct
alpha/beta-Hydrolases0Direct
Inhibitor of apoptosis (IAP) repeat0Direct
WWE domain0Direct
Ankyrin repeat0Direct
ARM repeat0Direct
TTHA0583/YokD-like0Direct
Kix domain of CBP (creb binding protein)0Direct
OMPA-like0Direct
Docking domain B of the erythromycin polyketide synthase (DEBS)0Direct
B-box zinc-binding domain0Direct
Ran binding protein zinc finger-like5.058e-16Direct
Chromo domain-like0.000000000000006928Direct
WD40 repeat-like0.00000000000002853Direct
Class II aaRS and biotin synthetases0.00000000000005943Direct
SAP domain0.0000000003099Direct
Pentapeptide repeat-like0.000000002456Direct
SMAD/FHA domain0.00000001394Direct
UBA-like0.00000009123Direct
SCP-like0.00000009459Direct
RCC1/BLIP-II0.0000003917Direct
Class I glutamine amidotransferase-like0.0000005077Direct
beta-beta-alpha zinc fingers0.0000005354Direct
Galactose oxidase, central domain0.0000005794Direct
C2 domain (Calcium/lipid-binding domain, CaLB)0.000005249Direct
Cyclin-like0.00002254Direct
Cysteine proteinases0.00002383Direct
Ubiquitin-like0.00009008Direct
Tropomyosin0.0001045Direct
TAF(II)230 TBP-binding fragment0.0003756Direct
vWA-like0.0004107Direct
CBS-domain pair0.0008151Direct
Formin homology 2 domain (FH2 domain)0.0009477Direct
Kelch motif0.001553Inherited
Acetyl-CoA synthetase-like0.002405Inherited
PFL-like glycyl radical enzymes0.002426Inherited
Homeodomain-like0.01406Inherited
EF-hand0.05391Inherited
Prismane protein-like0.07114Inherited
Zinc beta-ribbon0.07148Inherited
DEATH domain0.07862Inherited
Second domain of FERM0.1099Inherited
Glutamine synthetase, N-terminal domain0.2425Inherited
PDZ domain-like0.3005Inherited
SGNH hydrolase0.3513Inherited
Cyclophilin-like0.5104Inherited
Tudor/PWWP/MBT0.5311Inherited
Dimeric alpha+beta barrel0.761Inherited
RNA-binding domain, RBD0.7788Inherited
PYP-like sensor domain (PAS domain)0.8444Inherited
TPR-like0.9208Inherited
E set domains0.994Inherited
PLP-dependent transferases0.9999Inherited
Phosphoenolpyruvate/pyruvate domain1Inherited
Thioesterase/thiol ester dehydrase-isomerase1Inherited
Thiamin diphosphate-binding fold (THDP-binding)1Inherited
L domain-like1Inherited
Nucleic acid-binding proteins1Inherited
Succinyl-CoA synthetase domains1Inherited
PUA domain-like1Inherited
Galactose-binding domain-like1Inherited
NAD(P)-binding Rossmann-fold domains1Inherited
S-adenosyl-L-methionine-dependent methyltransferases1Inherited
Radical SAM enzymes1Inherited
Clavaminate synthase-like1Inherited
BRCT domain1Inherited
Glutamine synthetase/guanido kinase1Inherited
tRNA-binding arm1Inherited
DHS-like NAD/FAD-binding domain1Inherited
4'-phosphopantetheinyl transferase1Inherited
P-loop containing nucleoside triphosphate hydrolases1Inherited
Inosine monophosphate dehydrogenase (IMPDH)1Inherited
"Winged helix" DNA-binding domain1Inherited
Carbamate kinase-like1Inherited
Fibronectin type III1Inherited
FMN-linked oxidoreductases1Inherited
N-terminal nucleophile aminohydrolases (Ntn hydrolases)1Inherited
SH2 domain1Inherited
SH3-domain1Inherited
Zn-dependent exopeptidases1Inherited
GroES-like1Inherited
Glutathione synthetase ATP-binding domain-like1Inherited


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Family

(show details)
SCOP termFDR (all)Annotation (direct or inherited)
FabD-like0Direct
Filamin repeat (rod domain)0Direct
UBC-related0Direct
TAZ domain0Direct
U-box0Direct
DmpG/LeuA communication domain-like0Direct
Arylamine N-acetyltransferase0Direct
Glycerol-3-phosphate (1)-acyltransferase0Direct
Transcriptional factor domain0Direct
ZZ domain0Direct
Transglutaminase core0Direct
CPH domain0Direct
Chromo barrel domain0Direct
CCHHC domain0Direct
CHY zinc finger0Direct
PlsX-like0Direct
APC10-like0Direct
Mycobacterial antigens0Direct
Serine acetyltransferase0Direct
Tetrahydrodipicolinate-N-succinlytransferase, THDP-succinlytransferase, DapD0Direct
Acyl-carrier protein (ACP)0Direct
Gamma-glutamyltranspeptidase-like0Direct
Inhibitor of apoptosis (IAP) repeat0Direct
Thiolase-related0Direct
HLH, helix-loop-helix DNA-binding domain0Direct
N-acetyl transferase, NAT0Direct
Bromodomain0Direct
SWIB/MDM2 domain0Direct
Autoinducer synthetase0Direct
Methicillin resistance protein FemA probable tRNA-binding arm0Direct
N-terminal domain of cbl (N-cbl)0Direct
Ankyrin repeat0Direct
Phosphotransacetylase0Direct
SIAH, seven in absentia homolog0Direct
USP8 interacting domain0Direct
Transcription factor IIB (TFIIB), core domain0Direct
Ran binding protein zinc finger-like0Direct
CAT-like0Direct
WW domain0Direct
RING finger domain, C3HC40Direct
NHL repeat0Direct
CCCH zinc finger0Direct
Lrp/AsnC-like transcriptional regulator C-terminal domain0Direct
PAS domain of steroid receptor coactivator 1A, NCo-A10Direct
Probable ACP-binding domain of malonyl-CoA ACP transacylase0Direct
HMGL-like0Direct
Armadillo repeat0Direct
B-box zinc-binding domain0Direct
GABA-aminotransferase-like0Direct
PHD domain0Direct
Docking domain B of the erythromycin polyketide synthase (DEBS)0Direct
UDP-glucose pyrophosphorylase0Direct
Transglutaminase, two C-terminal domains0Direct
UDP N-acetylglucosamine acyltransferase0Direct
Biotinyl/lipoyl-carrier proteins and domains0Direct
FemXAB nonribosomal peptidyltransferases0Direct
BRCT domain0Direct
GlmU C-terminal domain-like0Direct
Homeodomain0Direct
Leucine zipper domain0Direct
Malate synthase G0Direct
SPRY domain0Direct
Kix domain of CBP (creb binding protein)0Direct
Trimerization domain of TRAF0Direct
Zinc hairpin stack0Direct
N-myristoyl transferase, NMT0Direct
Formylmethanofuran:tetrahydromethanopterin formyltransferase0Direct
Galactoside acetyltransferase-like0Direct
WWE domain0Direct
LplA-like0Direct
YeaZ-like0Direct
Nuclear receptor coactivator interlocking domain0Direct
Chalcone synthase-like0Direct
Transglutaminase N-terminal domain0Direct
O-acetyltransferase0Direct
Hypoxia-inducible factor Hif2a, C-terminal domain0Direct
PABC (PABP) domain0Direct
Phytochelatin synthase0Direct
LFTR-like0Direct
Choline/Carnitine O-acyltransferase0Direct
Glutaminyl-peptide cyclotransferase-like0Direct
2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain0Direct
Mib/herc2 domain0Direct
Outer membrane enzyme PagP0Direct
Acetyl-CoA synthase0Direct
AstA-like0Direct
Aminoglycoside 3-N-acetyltransferase-like0Direct
HTS-like0Direct
Citrate synthase0Direct
Hect, E3 ligase catalytic domain0Direct
Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex0Direct
ArgJ-like0Direct
Variant RING domain0Direct
MATH domain5.508e-16Direct
PFL-like0.000000000000001276Direct
WD40-repeat0.0000000000006344Direct
DRTGG domain0.0000000000008566Direct
Classic zinc finger, C2H20.00000000002093Direct
Pentapeptide repeats0.0000000001548Direct
SAP domain0.0000000001944Direct
SRA domain-like0.000000001206Direct
Ubiquitin-related0.000000002548Direct
Thioesterase domain of polypeptide, polyketide and fatty acid synthases0.000000003126Direct
Leucine rich effector protein YopM0.000000007638Direct
FHA domain0.000000008446Direct
Sterol carrier protein, SCP0.00000004363Direct
CoA-binding domain0.00000291Direct
Hypoxia-inducible factor HIF ihhibitor (FIH1)0.000003129Direct
FYVE, a phosphatidylinositol-3-phosphate binding domain0.000004Direct
Regulator of chromosome condensation RCC10.000004369Direct
Tropomyosin0.000004699Direct
EF-hand modules in multidomain proteins0.00001167Direct
Leucine carboxy methyltransferase Ppm10.00003083Direct
MaoC-like0.00003573Direct
PA domain0.00005616Direct
UBA domain0.0001174Direct
PDZ domain0.0001174Direct
CBS-domain pair0.0002431Direct
TAF(II)230 TBP-binding fragment0.0002926Direct
Acetyl-CoA synthetase-like0.0004047Direct
First domain of FERM0.003408Inherited
Third domain of FERM0.003408Inherited
Caspase recruitment domain, CARD0.0328Inherited
RWD domain0.04386Inherited
Branched-chain alpha-keto acid dehydrogenase Pyr module0.04583Inherited
Branched-chain alpha-keto acid dehydrogenase PP module0.04904Inherited
Second domain of FERM0.07786Inherited
Tetratricopeptide repeat (TPR)0.0998Inherited
Glutamine synthetase, N-terminal domain0.1489Inherited
Glutamine synthetase catalytic domain0.1813Inherited
PLC-like (P variant)0.2569Inherited
Cyclophilin (peptidylprolyl isomerase)0.3023Inherited
HpcH/HpaI aldolase0.4146Inherited
Chromo domain0.4499Inherited
Pyruvate oxidase and decarboxylase, middle domain0.6354Inherited
Serine carboxypeptidase-like0.8197Inherited
Alcohol dehydrogenase-like, C-terminal domain0.8622Inherited
Alcohol dehydrogenase-like, N-terminal domain0.9226Inherited
Fibronectin type III0.9347Inherited
Tyrosine-dependent oxidoreductases0.952Inherited
SH3-domain0.9644Inherited
Pyruvate oxidase and decarboxylase Pyr module1Inherited
N-acetyl-l-glutamate kinase1Inherited
Succinyl-CoA synthetase domains1Inherited
Pyruvate oxidase and decarboxylase PP module1Inherited
Holo-(acyl carrier protein) synthase ACPS1Inherited
Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain1Inherited
Class I aldolase1Inherited
Calmodulin-like1Inherited
Crotonase-like1Inherited
Succinyl-CoA synthetase, beta-chain, N-terminal domain1Inherited
SH2 domain1Inherited
Anticodon-binding domain1Inherited


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Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
PABC (PABP) domain0Direct
CoA-dependent acyltransferases0Direct
Thiolase-like0Direct
TAZ domain0Direct
UBC-like0Direct
B-box zinc-binding domain0Direct
ACP-like0Direct
alpha/beta-Hydrolases0Direct
Mib/herc2 domain-like0Direct
OMPA-like0Direct
WWE domain0Direct
Concanavalin A-like lectins/glucanases0Direct
Zinc hairpin stack0Direct
Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex0Direct
FYVE/PHD zinc finger0Direct
PA domain0Direct
Glycerol-3-phosphate (1)-acyltransferase0Direct
Formylmethanofuran:tetrahydromethanopterin formyltransferase0Direct
ClpS-like0Direct
Leucine zipper domain0Direct
Single hybrid motif0Direct
HLH, helix-loop-helix DNA-binding domain0Direct
N-terminal domain of cbl (N-cbl)0Direct
Malate synthase G0Direct
Probable ACP-binding domain of malonyl-CoA ACP transacylase0Direct
Acyl-CoA N-acyltransferases (Nat)0Direct
FabD/lysophospholipase-like0Direct
Aldolase0Direct
Bromodomain0Direct
Hect, E3 ligase catalytic domain0Direct
Inhibitor of apoptosis (IAP) repeat0Direct
Isocitrate/Isopropylmalate dehydrogenase-like0Direct
Transglutaminase, two C-terminal domains0Direct
Nucleotide-diphospho-sugar transferases0Direct
SWIB/MDM2 domain0Direct
CHY zinc finger-like0Direct
Actin-like ATPase domain0Direct
NHL repeat0Direct
Ankyrin repeat0Direct
RING/U-box0Direct
Citrate synthase0Direct
ARM repeat0Direct
2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain0Direct
CCCH zinc finger0Direct
WW domain0Direct
TRAF domain-like0Direct
Kix domain of CBP (creb binding protein)0Direct
NRDP1 C-terminal domain-like0Direct
Trimeric LpxA-like enzymes0Direct
DmpA/ArgJ-like0Direct
Trimerization domain of TRAF0Direct
CCHHC domain0Direct
Nuclear receptor coactivator interlocking domain0Direct
post-HMGL domain-like0Direct
HprK N-terminal domain-like0Direct
Docking domain B of the erythromycin polyketide synthase (DEBS)0Direct
TTHA0583/YokD-like0Direct
Ran binding protein zinc finger-like3.526e-16Direct
Chromo domain-like0.000000000000004873Direct
WD40 repeat-like0.0000000000000202Direct
Class II aaRS and biotin synthetases0.00000000000004222Direct
SAP domain0.0000000002294Direct
Pentapeptide repeat-like0.000000001844Direct
SMAD/FHA domain0.00000001056Direct
UBA-like0.00000006976Direct
SCP-like0.00000007235Direct
RCC1/BLIP-II0.000000303Direct
Class I glutamine amidotransferase-like0.0000003936Direct
beta-beta-alpha zinc fingers0.0000004155Direct
Galactose oxidase, central domain0.00000045Direct
C2 domain (Calcium/lipid-binding domain, CaLB)0.000004134Direct
Cyclin-like0.000018Direct
Cysteine proteinases0.00001904Direct
Ubiquitin-like0.00007278Direct
Tropomyosin0.00008462Direct
TAF(II)230 TBP-binding fragment0.0003067Direct
vWA-like0.0003361Direct
CBS-domain pair0.000673Direct
Formin homology 2 domain (FH2 domain)0.0007828Direct
Kelch motif0.001291Inherited
Acetyl-CoA synthetase-like0.002009Inherited
PFL-like glycyl radical enzymes0.002026Inherited
Homeodomain-like0.01197Inherited
EF-hand0.0467Inherited
Prismane protein-like0.0618Inherited
Zinc beta-ribbon0.06211Inherited
DEATH domain0.06842Inherited
Second domain of FERM0.09615Inherited
Glutamine synthetase, N-terminal domain0.2161Inherited
PDZ domain-like0.2705Inherited
SGNH hydrolase0.3171Inherited
Cyclophilin-like0.4656Inherited
Tudor/PWWP/MBT0.4851Inherited
Dimeric alpha+beta barrel0.6992Inherited
RNA-binding domain, RBD0.7158Inherited
PYP-like sensor domain (PAS domain)0.7774Inherited
TPR-like0.8492Inherited
E set domains0.9191Inherited
PLP-dependent transferases0.9249Inherited
Fibronectin type III0.9328Inherited
GroES-like0.9417Inherited
SH3-domain0.9606Inherited
4'-phosphopantetheinyl transferase1Inherited
Thioesterase/thiol ester dehydrase-isomerase1Inherited
S-adenosyl-L-methionine-dependent methyltransferases1Inherited
Glutamine synthetase/guanido kinase1Inherited
L domain-like1Inherited
BRCT domain1Inherited
FMN-linked oxidoreductases1Inherited
Thiamin diphosphate-binding fold (THDP-binding)1Inherited
Phosphoenolpyruvate/pyruvate domain1Inherited
NAD(P)-binding Rossmann-fold domains1Inherited
"Winged helix" DNA-binding domain1Inherited
Nucleic acid-binding proteins1Inherited
Inosine monophosphate dehydrogenase (IMPDH)1Inherited
SH2 domain1Inherited
tRNA-binding arm1Inherited
DHS-like NAD/FAD-binding domain1Inherited
Galactose-binding domain-like1Inherited
P-loop containing nucleoside triphosphate hydrolases1Inherited
N-terminal nucleophile aminohydrolases (Ntn hydrolases)1Inherited
Clavaminate synthase-like1Inherited
Succinyl-CoA synthetase domains1Inherited
Radical SAM enzymes1Inherited
Glutathione synthetase ATP-binding domain-like1Inherited
Zn-dependent exopeptidases1Inherited
PUA domain-like1Inherited
Carbamate kinase-like1Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
90229,57850
  • 90229 - CCCH zinc finger
  • 57850 - RING/U-box
  • 0Direct
    49785,50985
  • 49785 - Galactose-binding domain-like
  • 50985 - RCC1/BLIP-II
  • 0Direct
    49599,160088
  • 49599 - TRAF domain-like
  • 160088 - NRDP1 C-terminal domain-like
  • 0Direct
    117281,51197
  • 117281 - Kelch motif
  • 51197 - Clavaminate synthase-like
  • 0Direct
    53901,53901
  • 53901 - Thiolase-like
  • 53901 - Thiolase-like
  • 0Direct
    52151,55048
  • 52151 - FabD/lysophospholipase-like
  • 55048 - Probable ACP-binding domain of malonyl-CoA ACP transacylase
  • 0Direct
    68906,57850
  • 68906 - SAP domain
  • 57850 - RING/U-box
  • 0Direct
    55729,55729
  • 55729 - Acyl-CoA N-acyltransferases (Nat)
  • 55729 - Acyl-CoA N-acyltransferases (Nat)
  • 0Direct
    55112,55112
  • 55112 - Formylmethanofuran:tetrahydromethanopterin formyltransferase
  • 55112 - Formylmethanofuran:tetrahydromethanopterin formyltransferase
  • 0Direct
    161219,161245
  • 161219 - CHY zinc finger-like
  • 161245 - Zinc hairpin stack
  • 0Direct
    89000,110921
  • 89000 - post-HMGL domain-like
  • 110921 - 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain
  • 0Direct
    48403,52113
  • 48403 - Ankyrin repeat
  • 52113 - BRCT domain
  • 0Direct
    161245,57850
  • 161245 - Zinc hairpin stack
  • 57850 - RING/U-box
  • 0Direct
    90209,57850
  • 90209 - Ran binding protein zinc finger-like
  • 57850 - RING/U-box
  • 0Direct
    57953,49599
  • 57953 - Trimerization domain of TRAF
  • 49599 - TRAF domain-like
  • 0Direct
    47592,90209
  • 47592 - SWIB/MDM2 domain
  • 90209 - Ran binding protein zinc finger-like
  • 0Direct
    102114,55729
  • 102114 - Radical SAM enzymes
  • 55729 - Acyl-CoA N-acyltransferases (Nat)
  • 0Direct
    57850,49599
  • 57850 - RING/U-box
  • 49599 - TRAF domain-like
  • 0Direct
    90229,90229
  • 90229 - CCCH zinc finger
  • 90229 - CCCH zinc finger
  • 0Direct
    54001,49309
  • 54001 - Cysteine proteinases
  • 49309 - Transglutaminase, two C-terminal domains
  • 0Direct
    50044,50044
  • 50044 - SH3-domain
  • 50044 - SH3-domain
  • 0Direct
    57924,57924
  • 57924 - Inhibitor of apoptosis (IAP) repeat
  • 57924 - Inhibitor of apoptosis (IAP) repeat
  • 0Direct
    55550,57850
  • 55550 - SH2 domain
  • 57850 - RING/U-box
  • 0Direct
    48371,117839
  • 48371 - ARM repeat
  • 117839 - WWE domain
  • 0Direct
    57850,57933
  • 57850 - RING/U-box
  • 57933 - TAZ domain
  • 0Direct
    81296,101898
  • 81296 - E set domains
  • 101898 - NHL repeat
  • 0Direct
    57850,52540
  • 57850 - RING/U-box
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    51735,51735
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 0Direct
    75138,53659
  • 75138 - HprK N-terminal domain-like
  • 53659 - Isocitrate/Isopropylmalate dehydrogenase-like
  • 0Direct
    57850,101898
  • 57850 - RING/U-box
  • 101898 - NHL repeat
  • 0Direct
    51569,54909
  • 51569 - Aldolase
  • 54909 - Dimeric alpha+beta barrel
  • 0Direct
    47473,55550
  • 47473 - EF-hand
  • 55550 - SH2 domain
  • 0Direct
    57850,57667
  • 57850 - RING/U-box
  • 57667 - beta-beta-alpha zinc fingers
  • 0Direct
    57850,117839
  • 57850 - RING/U-box
  • 117839 - WWE domain
  • 0Direct
    50965,51197
  • 50965 - Galactose oxidase, central domain
  • 51197 - Clavaminate synthase-like
  • 0Direct
    53067,56112
  • 53067 - Actin-like ATPase domain
  • 56112 - Protein kinase-like (PK-like)
  • 0Direct
    51230,51230
  • 51230 - Single hybrid motif
  • 51230 - Single hybrid motif
  • 0Direct
    47459,55785
  • 47459 - HLH, helix-loop-helix DNA-binding domain
  • 55785 - PYP-like sensor domain (PAS domain)
  • 0Direct
    53901,55718
  • 53901 - Thiolase-like
  • 55718 - SCP-like
  • 0Direct
    159034,57850
  • 159034 - Mib/herc2 domain-like
  • 57850 - RING/U-box
  • 0Direct
    57903,57850
  • 57903 - FYVE/PHD zinc finger
  • 57850 - RING/U-box
  • 0Direct
    49599,49599
  • 49599 - TRAF domain-like
  • 49599 - TRAF domain-like
  • 0Direct
    51230,52777
  • 51230 - Single hybrid motif
  • 52777 - CoA-dependent acyltransferases
  • 0Direct
    52151,51412
  • 52151 - FabD/lysophospholipase-like
  • 51412 - Inosine monophosphate dehydrogenase (IMPDH)
  • 0Direct
    81296,54001
  • 81296 - E set domains
  • 54001 - Cysteine proteinases
  • 0Direct
    69593,47473
  • 69593 - Glycerol-3-phosphate (1)-acyltransferase
  • 47473 - EF-hand
  • 0Direct
    51735,48256
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 48256 - Citrate synthase
  • 0Direct
    54495,57850
  • 54495 - UBC-like
  • 57850 - RING/U-box
  • 0Direct
    52540,75138
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 75138 - HprK N-terminal domain-like
  • 0Direct
    49879,57850
  • 49879 - SMAD/FHA domain
  • 57850 - RING/U-box
  • 0Direct
    51230,47005
  • 51230 - Single hybrid motif
  • 47005 - Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex
  • 0Direct
    54160,55729
  • 54160 - Chromo domain-like
  • 55729 - Acyl-CoA N-acyltransferases (Nat)
  • 0Direct
    53448,51161
  • 53448 - Nucleotide-diphospho-sugar transferases
  • 51161 - Trimeric LpxA-like enzymes
  • 0Direct
    52540,55729
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 55729 - Acyl-CoA N-acyltransferases (Nat)
  • 0Direct
    49562,51045
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 51045 - WW domain
  • 0Direct
    54495,46934
  • 54495 - UBC-like
  • 46934 - UBA-like
  • 0Direct
    69593,56801
  • 69593 - Glycerol-3-phosphate (1)-acyltransferase
  • 56801 - Acetyl-CoA synthetase-like
  • 0Direct
    51735,47336
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 47336 - ACP-like
  • 0Direct
    51045,51045
  • 51045 - WW domain
  • 51045 - WW domain
  • 0Direct
    51569,89000
  • 51569 - Aldolase
  • 89000 - post-HMGL domain-like
  • 0Direct
    54236,90209
  • 54236 - Ubiquitin-like
  • 90209 - Ran binding protein zinc finger-like
  • 0Direct
    48403,57850
  • 48403 - Ankyrin repeat
  • 57850 - RING/U-box
  • 0Direct
    49309,49309
  • 49309 - Transglutaminase, two C-terminal domains
  • 49309 - Transglutaminase, two C-terminal domains
  • 0Direct
    52025,57850
  • 52025 - PA domain
  • 57850 - RING/U-box
  • 0Direct
    53633,55729
  • 53633 - Carbamate kinase-like
  • 55729 - Acyl-CoA N-acyltransferases (Nat)
  • 0Direct
    47005,52777
  • 47005 - Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex
  • 52777 - CoA-dependent acyltransferases
  • 0Direct
    49265,49899
  • 49265 - Fibronectin type III
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0Direct
    53067,53067
  • 53067 - Actin-like ATPase domain
  • 53067 - Actin-like ATPase domain
  • 0Direct
    55729,46589
  • 55729 - Acyl-CoA N-acyltransferases (Nat)
  • 46589 - tRNA-binding arm
  • 0Direct
    49599,57953
  • 49599 - TRAF domain-like
  • 57953 - Trimerization domain of TRAF
  • 0Direct
    52777,52777
  • 52777 - CoA-dependent acyltransferases
  • 52777 - CoA-dependent acyltransferases
  • 0Direct
    57783,47954
  • 57783 - Zinc beta-ribbon
  • 47954 - Cyclin-like
  • 0Direct
    46785,57903
  • 46785 - "Winged helix" DNA-binding domain
  • 57903 - FYVE/PHD zinc finger
  • 0Direct
    54637,52151
  • 54637 - Thioesterase/thiol ester dehydrase-isomerase
  • 52151 - FabD/lysophospholipase-like
  • 0Direct
    57850,48371
  • 57850 - RING/U-box
  • 48371 - ARM repeat
  • 0Direct
    53300,57850
  • 53300 - vWA-like
  • 57850 - RING/U-box
  • 0Direct
    56112,57850
  • 56112 - Protein kinase-like (PK-like)
  • 57850 - RING/U-box
  • 0Direct
    57850,57845
  • 57850 - RING/U-box
  • 57845 - B-box zinc-binding domain
  • 0Direct
    57850,50978
  • 57850 - RING/U-box
  • 50978 - WD40 repeat-like
  • 0Direct
    63570,56204
  • 63570 - PABC (PABP) domain
  • 56204 - Hect, E3 ligase catalytic domain
  • 0Direct
    49599,50156
  • 49599 - TRAF domain-like
  • 50156 - PDZ domain-like
  • 0Direct
    47668,47473
  • 47668 - N-terminal domain of cbl (N-cbl)
  • 47473 - EF-hand
  • 0Direct
    53335,50965
  • 53335 - S-adenosyl-L-methionine-dependent methyltransferases
  • 50965 - Galactose oxidase, central domain
  • 0Direct
    57850,57850
  • 57850 - RING/U-box
  • 57850 - RING/U-box
  • 0Direct
    57850,159034
  • 57850 - RING/U-box
  • 159034 - Mib/herc2 domain-like
  • 0Direct
    53474,54631
  • 53474 - alpha/beta-Hydrolases
  • 54631 - CBS-domain pair
  • 0Direct
    117839,117839
  • 117839 - WWE domain
  • 117839 - WWE domain
  • 0Direct
    51045,56204
  • 51045 - WW domain
  • 56204 - Hect, E3 ligase catalytic domain
  • 0Direct
    47954,47954
  • 47954 - Cyclin-like
  • 47954 - Cyclin-like
  • 0Direct
    52210,51735
  • 52210 - Succinyl-CoA synthetase domains
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 0Direct
    48452,57850
  • 48452 - TPR-like
  • 57850 - RING/U-box
  • 0Direct
    49785,159034
  • 49785 - Galactose-binding domain-like
  • 159034 - Mib/herc2 domain-like
  • 0Direct
    46589,55729
  • 46589 - tRNA-binding arm
  • 55729 - Acyl-CoA N-acyltransferases (Nat)
  • 0Direct
    55729,47370
  • 55729 - Acyl-CoA N-acyltransferases (Nat)
  • 47370 - Bromodomain
  • 0Direct
    47336,53474
  • 47336 - ACP-like
  • 53474 - alpha/beta-Hydrolases
  • 0.00000000000008008Direct
    52113,52113
  • 52113 - BRCT domain
  • 52113 - BRCT domain
  • 0.00000000000008669Direct
    49899,49899
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.000000001387Direct
    53335,51735
  • 53335 - S-adenosyl-L-methionine-dependent methyltransferases
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 0.000000306Direct
    57903,47370
  • 57903 - FYVE/PHD zinc finger
  • 47370 - Bromodomain
  • 0.000018Direct
    48371,48403
  • 48371 - ARM repeat
  • 48403 - Ankyrin repeat
  • 0.00003956Direct
    47336,52777
  • 47336 - ACP-like
  • 52777 - CoA-dependent acyltransferases
  • 0.0001056Direct
    47370,47370
  • 47370 - Bromodomain
  • 47370 - Bromodomain
  • 0.0003067Direct
    54236,47031
  • 54236 - Ubiquitin-like
  • 47031 - Second domain of FERM
  • 0.00364Inherited
    57667,57667
  • 57667 - beta-beta-alpha zinc fingers
  • 57667 - beta-beta-alpha zinc fingers
  • 0.00364Inherited
    47031,50729
  • 47031 - Second domain of FERM
  • 50729 - PH domain-like
  • 0.02876Inherited
    55785,55785
  • 55785 - PYP-like sensor domain (PAS domain)
  • 55785 - PYP-like sensor domain (PAS domain)
  • 0.05156Inherited
    57903,57903
  • 57903 - FYVE/PHD zinc finger
  • 57903 - FYVE/PHD zinc finger
  • 0.07981Inherited
    48371,48371
  • 48371 - ARM repeat
  • 48371 - ARM repeat
  • 0.09615Inherited
    48452,48452
  • 48452 - TPR-like
  • 48452 - TPR-like
  • 0.1751Inherited
    51735,50129
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 50129 - GroES-like
  • 0.1776Inherited
    54368,55931
  • 54368 - Glutamine synthetase, N-terminal domain
  • 55931 - Glutamine synthetase/guanido kinase
  • 0.2161Inherited
    50129,51735
  • 50129 - GroES-like
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 0.9356Inherited
    52518,52467
  • 52518 - Thiamin diphosphate-binding fold (THDP-binding)
  • 52467 - DHS-like NAD/FAD-binding domain
  • 1Inherited
    52467,52518
  • 52467 - DHS-like NAD/FAD-binding domain
  • 52518 - Thiamin diphosphate-binding fold (THDP-binding)
  • 1Inherited
    56059,52210
  • 56059 - Glutathione synthetase ATP-binding domain-like
  • 52210 - Succinyl-CoA synthetase domains
  • 1Inherited
    52518,52518
  • 52518 - Thiamin diphosphate-binding fold (THDP-binding)
  • 52518 - Thiamin diphosphate-binding fold (THDP-binding)
  • 1Inherited
    50249,55681
  • 50249 - Nucleic acid-binding proteins
  • 55681 - Class II aaRS and biotin synthetases
  • 1Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    49599,57953,49599
  • 49599 - TRAF domain-like
  • 57953 - Trimerization domain of TRAF
  • 49599 - TRAF domain-like
  • 0Direct
    51735,51735,47336
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 47336 - ACP-like
  • 0Direct
    51230,47005,52777
  • 51230 - Single hybrid motif
  • 47005 - Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex
  • 52777 - CoA-dependent acyltransferases
  • 0Direct
    53901,53901,55718
  • 53901 - Thiolase-like
  • 53901 - Thiolase-like
  • 55718 - SCP-like
  • 0Direct
    47473,55550,57850
  • 47473 - EF-hand
  • 55550 - SH2 domain
  • 57850 - RING/U-box
  • 0Direct
    52540,75138,53659
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 75138 - HprK N-terminal domain-like
  • 53659 - Isocitrate/Isopropylmalate dehydrogenase-like
  • 0Direct
    54001,49309,49309
  • 54001 - Cysteine proteinases
  • 49309 - Transglutaminase, two C-terminal domains
  • 49309 - Transglutaminase, two C-terminal domains
  • 0Direct
    53335,50965,51197
  • 53335 - S-adenosyl-L-methionine-dependent methyltransferases
  • 50965 - Galactose oxidase, central domain
  • 51197 - Clavaminate synthase-like
  • 0Direct
    54236,90209,57850
  • 54236 - Ubiquitin-like
  • 90209 - Ran binding protein zinc finger-like
  • 57850 - RING/U-box
  • 0Direct
    51230,51230,47005
  • 51230 - Single hybrid motif
  • 51230 - Single hybrid motif
  • 47005 - Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex
  • 0Direct
    57924,57924,57924
  • 57924 - Inhibitor of apoptosis (IAP) repeat
  • 57924 - Inhibitor of apoptosis (IAP) repeat
  • 57924 - Inhibitor of apoptosis (IAP) repeat
  • 0Direct
    48403,52113,52113
  • 48403 - Ankyrin repeat
  • 52113 - BRCT domain
  • 52113 - BRCT domain
  • 0Direct
    57850,49599,160088
  • 57850 - RING/U-box
  • 49599 - TRAF domain-like
  • 160088 - NRDP1 C-terminal domain-like
  • 0Direct
    47459,55785,55785
  • 47459 - HLH, helix-loop-helix DNA-binding domain
  • 55785 - PYP-like sensor domain (PAS domain)
  • 55785 - PYP-like sensor domain (PAS domain)
  • 0Direct
    159034,57850,159034
  • 159034 - Mib/herc2 domain-like
  • 57850 - RING/U-box
  • 159034 - Mib/herc2 domain-like
  • 0Direct
    51735,47336,53474
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 47336 - ACP-like
  • 53474 - alpha/beta-Hydrolases
  • 0Direct
    55729,46589,55729
  • 55729 - Acyl-CoA N-acyltransferases (Nat)
  • 46589 - tRNA-binding arm
  • 55729 - Acyl-CoA N-acyltransferases (Nat)
  • 0Direct
    57850,57850,57850
  • 57850 - RING/U-box
  • 57850 - RING/U-box
  • 57850 - RING/U-box
  • 0Direct
    57850,48371,48371
  • 57850 - RING/U-box
  • 48371 - ARM repeat
  • 48371 - ARM repeat
  • 0Direct
    47668,47473,55550
  • 47668 - N-terminal domain of cbl (N-cbl)
  • 47473 - EF-hand
  • 55550 - SH2 domain
  • 0Direct
    52210,51735,48256
  • 52210 - Succinyl-CoA synthetase domains
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 48256 - Citrate synthase
  • 0Direct
    57850,57850,57933
  • 57850 - RING/U-box
  • 57850 - RING/U-box
  • 57933 - TAZ domain
  • 0Direct
    49599,49599,49599
  • 49599 - TRAF domain-like
  • 49599 - TRAF domain-like
  • 49599 - TRAF domain-like
  • 0Direct
    81296,54001,49309
  • 81296 - E set domains
  • 54001 - Cysteine proteinases
  • 49309 - Transglutaminase, two C-terminal domains
  • 0Direct
    161219,161245,57850
  • 161219 - CHY zinc finger-like
  • 161245 - Zinc hairpin stack
  • 57850 - RING/U-box
  • 0Direct
    51045,51045,56204
  • 51045 - WW domain
  • 51045 - WW domain
  • 56204 - Hect, E3 ligase catalytic domain
  • 0Direct
    51569,89000,110921
  • 51569 - Aldolase
  • 89000 - post-HMGL domain-like
  • 110921 - 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain
  • 0Direct
    46785,57903,57903
  • 46785 - "Winged helix" DNA-binding domain
  • 57903 - FYVE/PHD zinc finger
  • 57903 - FYVE/PHD zinc finger
  • 0Direct
    90209,57850,57850
  • 90209 - Ran binding protein zinc finger-like
  • 57850 - RING/U-box
  • 57850 - RING/U-box
  • 0Direct
    57783,47954,47954
  • 57783 - Zinc beta-ribbon
  • 47954 - Cyclin-like
  • 47954 - Cyclin-like
  • 0Direct
    51735,50129,51735
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 50129 - GroES-like
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 0Direct
    51735,47336,52777
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 47336 - ACP-like
  • 52777 - CoA-dependent acyltransferases
  • 0Direct
    57850,49599,50156
  • 57850 - RING/U-box
  • 49599 - TRAF domain-like
  • 50156 - PDZ domain-like
  • 0Direct
    50129,51735,51735
  • 50129 - GroES-like
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 0Direct
    57850,49599,49599
  • 57850 - RING/U-box
  • 49599 - TRAF domain-like
  • 49599 - TRAF domain-like
  • 0Direct
    51230,51230,51230
  • 51230 - Single hybrid motif
  • 51230 - Single hybrid motif
  • 51230 - Single hybrid motif
  • 0Direct
    51045,51045,51045
  • 51045 - WW domain
  • 51045 - WW domain
  • 51045 - WW domain
  • 0Direct
    56059,52210,51735
  • 56059 - Glutathione synthetase ATP-binding domain-like
  • 52210 - Succinyl-CoA synthetase domains
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 0Direct
    47336,52777,52777
  • 47336 - ACP-like
  • 52777 - CoA-dependent acyltransferases
  • 52777 - CoA-dependent acyltransferases
  • 0.0001056Direct
    57667,57667,57667
  • 57667 - beta-beta-alpha zinc fingers
  • 57667 - beta-beta-alpha zinc fingers
  • 57667 - beta-beta-alpha zinc fingers
  • 0.0002891Direct
    54236,47031,50729
  • 54236 - Ubiquitin-like
  • 47031 - Second domain of FERM
  • 50729 - PH domain-like
  • 0.00364Inherited
    53067,53067,53067
  • 53067 - Actin-like ATPase domain
  • 53067 - Actin-like ATPase domain
  • 53067 - Actin-like ATPase domain
  • 0.2626Inherited
    52518,52467,52518
  • 52518 - Thiamin diphosphate-binding fold (THDP-binding)
  • 52467 - DHS-like NAD/FAD-binding domain
  • 52518 - Thiamin diphosphate-binding fold (THDP-binding)
  • 1Inherited


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