SUPERFAMILY 1.75 HMM library and genome assignments server

Superfamily is undergoing a server migration - you are now browsing on the new server. Please contact us if you experience any problems.

Enzyme Commission (EC): RING-type E3 ubiquitin transferase

(show info)

Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Root: EC Hierarchy (from IntEnz release 70)

Shortest distance to current term (+ for parents, - for children) EC term [EC ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + 4:   root [root] <7>
+ + + 3:   Transferases [2] <10>(449|683) (448|546|278)
+ + 2:   Acyltransferases [2.3] <3>(129|155) (129|117|43)
+ 1:   Aminoacyltransferases [2.3.2] <32>(61|68) (61|65|22)
0:   RING-type E3 ubiquitin transferase [2.3.2.27](37|41) (37|45|14)


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Superfamily

(show details)
SCOP termFDR (all)Annotation (direct or inherited)
SMAD/FHA domain0Direct
NRDP1 C-terminal domain-like0Direct
RING/U-box0Direct
Trimerization domain of TRAF0Direct
PA domain0Direct
SWIB/MDM2 domain0Direct
TRAF domain-like0Direct
N-terminal domain of cbl (N-cbl)0Direct
Concanavalin A-like lectins/glucanases0Direct
Inhibitor of apoptosis (IAP) repeat0Direct
CHY zinc finger-like0Direct
ClpS-like0Direct
SAP domain0Direct
B-box zinc-binding domain0Direct
beta-beta-alpha zinc fingers0Direct
CCCH zinc finger0Direct
NHL repeat0Direct
Zinc hairpin stack0Direct
vWA-like0.000000000001811Direct
SH3-domain0.00000000002233Direct
L domain-like0.0000000004018Direct
Fibronectin type III0.0000000008289Direct
SH2 domain0.000000001023Direct
Cyclophilin-like0.0000000153Direct
Bromodomain0.00000004438Direct
FYVE/PHD zinc finger0.00000004505Direct
Formin homology 2 domain (FH2 domain)0.00000009545Direct
WD40 repeat-like0.0000001232Direct
EF-hand0.00000027Direct
Second domain of FERM0.0000002943Direct
DEATH domain0.000001604Direct
PDZ domain-like0.0000145Direct
ARM repeat0.00004014Direct
TPR-like0.00004557Direct
BRCT domain0.0005671Direct
PUA domain-like0.0006365Direct
RNA-binding domain, RBD0.0006515Direct


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

(show details)
SCOP termFDR (all)Annotation (direct or inherited)
Zinc hairpin stack0Direct
SWIB/MDM2 domain0Direct
NHL repeat0Direct
SIAH, seven in absentia homolog0Direct
N-terminal domain of cbl (N-cbl)0Direct
U-box0Direct
Classic zinc finger, C2H20Direct
BRCT domain0Direct
B-box zinc-binding domain0Direct
FHA domain0Direct
ZZ domain0Direct
Inhibitor of apoptosis (IAP) repeat0Direct
RING finger domain, C3HC40Direct
SAP domain0Direct
Filamin repeat (rod domain)0Direct
CHY zinc finger0Direct
Trimerization domain of TRAF0Direct
FYVE, a phosphatidylinositol-3-phosphate binding domain0Direct
MATH domain0Direct
USP8 interacting domain0Direct
Variant RING domain0Direct
SPRY domain0Direct
SRA domain-like0Direct
CCCH zinc finger0Direct
Leucine rich effector protein YopM5.525e-16Direct
EF-hand modules in multidomain proteins0.000000000000001099Direct
PA domain0.0000000000006398Direct
SH3-domain0.00000000000105Direct
Fibronectin type III0.00000000004233Direct
PDZ domain0.00000000004456Direct
SH2 domain0.00000000005795Direct
Cyclophilin (peptidylprolyl isomerase)0.0000000005041Direct
First domain of FERM0.00000000326Direct
Third domain of FERM0.000000005624Direct
Bromodomain0.000000008267Direct
Second domain of FERM0.0000000574Direct
RWD domain0.0000003667Direct
Tetratricopeptide repeat (TPR)0.0000004408Direct
WD40-repeat0.000004666Direct
Caspase recruitment domain, CARD0.00001726Direct
PHD domain0.00004399Direct


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
Plot tree as:   Download Newick format tree:
(show help)

Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

(show details)
Supra-domain (Single) FDR (all) Annotation (direct or inherited)
CCCH zinc finger0Direct
RING/U-box0Direct
SMAD/FHA domain0Direct
NRDP1 C-terminal domain-like0Direct
TRAF domain-like0Direct
SWIB/MDM2 domain0Direct
Inhibitor of apoptosis (IAP) repeat0Direct
CHY zinc finger-like0Direct
B-box zinc-binding domain0Direct
Concanavalin A-like lectins/glucanases0Direct
SAP domain0Direct
Zinc hairpin stack0Direct
ClpS-like0Direct
PA domain0Direct
Trimerization domain of TRAF0Direct
NHL repeat0Direct
N-terminal domain of cbl (N-cbl)0Direct
beta-beta-alpha zinc fingers0Direct
vWA-like0.000000000001306Direct
SH3-domain0.00000000001628Direct
L domain-like0.000000000298Direct
Fibronectin type III0.0000000006175Direct
SH2 domain0.0000000007632Direct
Cyclophilin-like0.00000001159Direct
Bromodomain0.00000003381Direct
FYVE/PHD zinc finger0.00000003434Direct
Formin homology 2 domain (FH2 domain)0.00000007305Direct
WD40 repeat-like0.00000009446Direct
EF-hand0.0000002083Direct
Second domain of FERM0.0000002274Direct
DEATH domain0.000001256Direct
PDZ domain-like0.00001153Direct
ARM repeat0.00003213Direct
TPR-like0.00003652Direct
BRCT domain0.0004654Direct
PUA domain-like0.0005232Direct
RNA-binding domain, RBD0.0005357Direct

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
57850,101898
  • 57850 - RING/U-box
  • 101898 - NHL repeat
  • 0Direct
    47592,90209
  • 47592 - SWIB/MDM2 domain
  • 90209 - Ran binding protein zinc finger-like
  • 0Direct
    49599,57953
  • 49599 - TRAF domain-like
  • 57953 - Trimerization domain of TRAF
  • 0Direct
    56112,57850
  • 56112 - Protein kinase-like (PK-like)
  • 57850 - RING/U-box
  • 0Direct
    57850,159034
  • 57850 - RING/U-box
  • 159034 - Mib/herc2 domain-like
  • 0Direct
    49599,160088
  • 49599 - TRAF domain-like
  • 160088 - NRDP1 C-terminal domain-like
  • 0Direct
    52025,57850
  • 52025 - PA domain
  • 57850 - RING/U-box
  • 0Direct
    57924,57924
  • 57924 - Inhibitor of apoptosis (IAP) repeat
  • 57924 - Inhibitor of apoptosis (IAP) repeat
  • 0Direct
    52113,52113
  • 52113 - BRCT domain
  • 52113 - BRCT domain
  • 0Direct
    47668,47473
  • 47668 - N-terminal domain of cbl (N-cbl)
  • 47473 - EF-hand
  • 0Direct
    57850,49599
  • 57850 - RING/U-box
  • 49599 - TRAF domain-like
  • 0Direct
    57850,57667
  • 57850 - RING/U-box
  • 57667 - beta-beta-alpha zinc fingers
  • 0Direct
    90229,57850
  • 90229 - CCCH zinc finger
  • 57850 - RING/U-box
  • 0Direct
    57850,117839
  • 57850 - RING/U-box
  • 117839 - WWE domain
  • 0Direct
    90229,90229
  • 90229 - CCCH zinc finger
  • 90229 - CCCH zinc finger
  • 0Direct
    81296,101898
  • 81296 - E set domains
  • 101898 - NHL repeat
  • 0Direct
    49599,49599
  • 49599 - TRAF domain-like
  • 49599 - TRAF domain-like
  • 0Direct
    57850,57845
  • 57850 - RING/U-box
  • 57845 - B-box zinc-binding domain
  • 0Direct
    68906,57850
  • 68906 - SAP domain
  • 57850 - RING/U-box
  • 0Direct
    159034,57850
  • 159034 - Mib/herc2 domain-like
  • 57850 - RING/U-box
  • 0Direct
    49599,50156
  • 49599 - TRAF domain-like
  • 50156 - PDZ domain-like
  • 0Direct
    48452,57850
  • 48452 - TPR-like
  • 57850 - RING/U-box
  • 0Direct
    48403,57850
  • 48403 - Ankyrin repeat
  • 57850 - RING/U-box
  • 0Direct
    48403,52113
  • 48403 - Ankyrin repeat
  • 52113 - BRCT domain
  • 0Direct
    49879,57850
  • 49879 - SMAD/FHA domain
  • 57850 - RING/U-box
  • 0Direct
    57850,52540
  • 57850 - RING/U-box
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    50044,50044
  • 50044 - SH3-domain
  • 50044 - SH3-domain
  • 0Direct
    57850,50978
  • 57850 - RING/U-box
  • 50978 - WD40 repeat-like
  • 0Direct
    57903,57850
  • 57903 - FYVE/PHD zinc finger
  • 57850 - RING/U-box
  • 0Direct
    53300,57850
  • 53300 - vWA-like
  • 57850 - RING/U-box
  • 0Direct
    47473,55550
  • 47473 - EF-hand
  • 55550 - SH2 domain
  • 0Direct
    57850,48371
  • 57850 - RING/U-box
  • 48371 - ARM repeat
  • 0Direct
    161245,57850
  • 161245 - Zinc hairpin stack
  • 57850 - RING/U-box
  • 0Direct
    161219,161245
  • 161219 - CHY zinc finger-like
  • 161245 - Zinc hairpin stack
  • 0Direct
    55550,57850
  • 55550 - SH2 domain
  • 57850 - RING/U-box
  • 0Direct
    57953,49599
  • 57953 - Trimerization domain of TRAF
  • 49599 - TRAF domain-like
  • 0Direct
    49899,49899
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0Direct
    117839,117839
  • 117839 - WWE domain
  • 117839 - WWE domain
  • 0Direct
    49265,49899
  • 49265 - Fibronectin type III
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0Direct
    57903,47370
  • 57903 - FYVE/PHD zinc finger
  • 47370 - Bromodomain
  • 0.00000000000003172Direct
    57667,57667
  • 57667 - beta-beta-alpha zinc fingers
  • 57667 - beta-beta-alpha zinc fingers
  • 0.000000001431Direct
    54236,47031
  • 54236 - Ubiquitin-like
  • 47031 - Second domain of FERM
  • 0.00000001907Direct
    48371,48371
  • 48371 - ARM repeat
  • 48371 - ARM repeat
  • 0.00000003134Direct
    47031,50729
  • 47031 - Second domain of FERM
  • 50729 - PH domain-like
  • 0.0000000754Direct
    48452,48452
  • 48452 - TPR-like
  • 48452 - TPR-like
  • 0.00002819Direct

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    57850,48371,48371
  • 57850 - RING/U-box
  • 48371 - ARM repeat
  • 48371 - ARM repeat
  • 0Direct
    57924,57924,57924
  • 57924 - Inhibitor of apoptosis (IAP) repeat
  • 57924 - Inhibitor of apoptosis (IAP) repeat
  • 57924 - Inhibitor of apoptosis (IAP) repeat
  • 0Direct
    161219,161245,57850
  • 161219 - CHY zinc finger-like
  • 161245 - Zinc hairpin stack
  • 57850 - RING/U-box
  • 0Direct
    57850,49599,160088
  • 57850 - RING/U-box
  • 49599 - TRAF domain-like
  • 160088 - NRDP1 C-terminal domain-like
  • 0Direct
    49599,57953,49599
  • 49599 - TRAF domain-like
  • 57953 - Trimerization domain of TRAF
  • 49599 - TRAF domain-like
  • 0Direct
    47473,55550,57850
  • 47473 - EF-hand
  • 55550 - SH2 domain
  • 57850 - RING/U-box
  • 0Direct
    49599,49599,49599
  • 49599 - TRAF domain-like
  • 49599 - TRAF domain-like
  • 49599 - TRAF domain-like
  • 0Direct
    47668,47473,55550
  • 47668 - N-terminal domain of cbl (N-cbl)
  • 47473 - EF-hand
  • 55550 - SH2 domain
  • 0Direct
    57850,49599,50156
  • 57850 - RING/U-box
  • 49599 - TRAF domain-like
  • 50156 - PDZ domain-like
  • 0Direct
    48403,52113,52113
  • 48403 - Ankyrin repeat
  • 52113 - BRCT domain
  • 52113 - BRCT domain
  • 0Direct
    159034,57850,159034
  • 159034 - Mib/herc2 domain-like
  • 57850 - RING/U-box
  • 159034 - Mib/herc2 domain-like
  • 0Direct
    57850,49599,49599
  • 57850 - RING/U-box
  • 49599 - TRAF domain-like
  • 49599 - TRAF domain-like
  • 0Direct
    57667,57667,57667
  • 57667 - beta-beta-alpha zinc fingers
  • 57667 - beta-beta-alpha zinc fingers
  • 57667 - beta-beta-alpha zinc fingers
  • 0.0000000002073Direct
    54236,47031,50729
  • 54236 - Ubiquitin-like
  • 47031 - Second domain of FERM
  • 50729 - PH domain-like
  • 0.00000001907Direct


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
    (show help)