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Enzyme Commission (EC): Transferring alkyl or aryl groups, other than methyl groups

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Root: EC Hierarchy (from IntEnz release 70)

Shortest distance to current term (+ for parents, - for children) EC term [EC ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + 2:   root [root] <7>
+ 1:   Transferases [2] <10>(449|683) (448|545|278)
0:   Transferring alkyl or aryl groups, other than methyl groups [2.5] <1>(43|47) (42|21|8)
- 1:   Transferring alkyl or aryl groups, other than methyl groups [2.5.1] <161>(42|46) (41|21|8)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain0Direct
Terpenoid synthases0Direct
Thioredoxin-like0Direct
AFP III-like domain0Direct
Aldolase0Direct
Tryptophan synthase beta subunit-like PLP-dependent enzymes0Direct
Protein prenylyltransferase0Direct
NadA-like0Direct
Dihydropteroate synthetase-like0Direct
Cobalamin adenosyltransferase-like0Direct
Periplasmic binding protein-like II0Direct
P-loop containing nucleoside triphosphate hydrolases0Direct
Rab geranylgeranyltransferase alpha-subunit, insert domain0Direct
Homo-oligomeric flavin-containing Cys decarboxylases, HFCD0Direct
Lumazine synthase0Direct
S-adenosylmethionine synthetase0Direct
FMN-linked oxidoreductases0Direct
GST C-terminal domain-like0Direct
Undecaprenyl diphosphate synthase0Direct
EPT/RTPC-like0Direct
LanC-like0Direct
DHS-like NAD/FAD-binding domain0Direct
Thiamin phosphate synthase0Direct
Prenyltransferase-like0Direct
Dehydroquinate synthase-like0.000000000000002009Direct
MAPEG domain-like0.000000003565Direct
MFS general substrate transporter0.00000003809Direct
Outer arm dynein light chain 10.0000002163Direct
Terpenoid cyclases/Protein prenyltransferases0.0000005584Direct
6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, HPPK0.000005948Direct
FAD-linked oxidases, C-terminal domain0.00001468Direct
Multidrug efflux transporter AcrB transmembrane domain0.00002249Direct
Aminoacid dehydrogenase-like, N-terminal domain0.002347Inherited
Riboflavin synthase domain-like0.05317Inherited
SCOP hierarchy in SUPERFAMILY0.3925Inherited
L domain-like1Inherited
PLP-dependent transferases1Inherited
Ribokinase-like1Inherited
FAD-binding/transporter-associated domain-like1Inherited
Tetrahydrobiopterin biosynthesis enzymes-like1Inherited
NAD(P)-binding Rossmann-fold domains1Inherited
S-adenosyl-L-methionine-dependent methyltransferases1Inherited
Radical SAM enzymes1Inherited


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

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SCOP termFDR (all)Annotation (direct or inherited)
Lumazine synthase0Direct
Deoxyhypusine synthase, DHS0Direct
Protein prenylyltransferase0Direct
Class I DAHP synthetase0Direct
SepSecS-like0Direct
AFP III-like domain0Direct
Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain0Direct
Phosphate binding protein-like0Direct
Dihydropteroate synthetase0Direct
Isoprenyl diphosphate synthases0Direct
Rab geranylgeranyltransferase alpha-subunit, insert domain0Direct
Enolpyruvate transferase, EPT0Direct
Phosphomethylpyrimidine kinase C-terminal domain-like0Direct
Squalene synthase0Direct
S-adenosylmethionine synthetase0Direct
Homo-oligomeric flavin-containing Cys decarboxylases, HFCD0Direct
Cobalamin adenosyltransferase0Direct
Prenyltransferase-like0Direct
Riboflavin synthase0Direct
NadA-like0Direct
Tryptophan synthase beta subunit-like PLP-dependent enzymes0Direct
Class-II DAHP synthetase0Direct
LanC-like0Direct
Glutathione S-transferase (GST), C-terminal domain0Direct
FMN-linked oxidoreductases0Direct
Protein prenyltransferases0Direct
Dehydroquinate synthase, DHQS0Direct
Glutathione S-transferase (GST), N-terminal domain0Direct
Thiamin phosphate synthase0Direct
Shikimate dehydrogenase-like0Direct
Spermidine synthase0Direct
NeuB-like0Direct
Undecaprenyl diphosphate synthase0Direct
DsbA-like0.000000000525Direct
MAPEG domain0.000000000717Direct
Shikimate kinase (AroK)0.00000001112Direct
Outer arm dynein light chain 10.0000001094Direct
6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, HPPK0.00000365Direct
Class I aldolase0.002142Inherited
DHN aldolase/epimerase0.005641Inherited
Met-10+ protein-like0.01358Inherited
FAD-linked oxidases, N-terminal domain0.1002Inherited
Cystathionine synthase-like0.9985Inherited
Thiamin biosynthesis kinases1Inherited
Aminoacid dehydrogenase-like, C-terminal domain1Inherited
Biotin synthase1Inherited
RecA protein-like (ATPase-domain)1Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Periplasmic binding protein-like II0Direct
DHS-like NAD/FAD-binding domain0Direct
Undecaprenyl diphosphate synthase0Direct
Protein prenylyltransferase0Direct
Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain0Direct
NadA-like0Direct
Prenyltransferase-like0Direct
Rab geranylgeranyltransferase alpha-subunit, insert domain0Direct
Dihydropteroate synthetase-like0Direct
Tryptophan synthase beta subunit-like PLP-dependent enzymes0Direct
P-loop containing nucleoside triphosphate hydrolases0Direct
Cobalamin adenosyltransferase-like0Direct
FMN-linked oxidoreductases0Direct
Thiamin phosphate synthase0Direct
Terpenoid synthases0Direct
Thioredoxin-like0Direct
Aldolase0Direct
AFP III-like domain0Direct
Lumazine synthase0Direct
S-adenosylmethionine synthetase0Direct
EPT/RTPC-like0Direct
LanC-like0Direct
GST C-terminal domain-like0Direct
Homo-oligomeric flavin-containing Cys decarboxylases, HFCD0Direct
Dehydroquinate synthase-like0.000000000000001407Direct
MAPEG domain-like0.000000002677Direct
MFS general substrate transporter0.00000002899Direct
Outer arm dynein light chain 10.0000001666Direct
Terpenoid cyclases/Protein prenyltransferases0.0000004337Direct
6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, HPPK0.000004687Direct
FAD-linked oxidases, C-terminal domain0.00001168Direct
Multidrug efflux transporter AcrB transmembrane domain0.00001794Direct
Aminoacid dehydrogenase-like, N-terminal domain0.001957Inherited
Riboflavin synthase domain-like0.04603Inherited
FAD-binding/transporter-associated domain-like1Inherited
Radical SAM enzymes1Inherited
Tetrahydrobiopterin biosynthesis enzymes-like1Inherited
PLP-dependent transferases1Inherited
Ribokinase-like1Inherited
S-adenosyl-L-methionine-dependent methyltransferases1Inherited
L domain-like1Inherited
NAD(P)-binding Rossmann-fold domains1Inherited

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
55205,52540
  • 55205 - EPT/RTPC-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    56796,55205
  • 56796 - Dehydroquinate synthase-like
  • 55205 - EPT/RTPC-like
  • 0Direct
    52540,51569
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 51569 - Aldolase
  • 0Direct
    52833,47616
  • 52833 - Thioredoxin-like
  • 47616 - GST C-terminal domain-like
  • 0Direct
    49594,52075
  • 49594 - Rab geranylgeranyltransferase alpha-subunit, insert domain
  • 52075 - Outer arm dynein light chain 1
  • 0Direct
    103473,53335
  • 103473 - MFS general substrate transporter
  • 53335 - S-adenosyl-L-methionine-dependent methyltransferases
  • 0Direct
    53613,51391
  • 53613 - Ribokinase-like
  • 51391 - Thiamin phosphate synthase
  • 0Direct
    55083,51717
  • 55083 - 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, HPPK
  • 51717 - Dihydropteroate synthetase-like
  • 0Direct
    53850,54782
  • 53850 - Periplasmic binding protein-like II
  • 54782 - Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain
  • 0Direct
    63380,63380
  • 63380 - Riboflavin synthase domain-like
  • 63380 - Riboflavin synthase domain-like
  • 0Direct
    51391,53613
  • 51391 - Thiamin phosphate synthase
  • 53613 - Ribokinase-like
  • 0Direct
    51569,51269
  • 51569 - Aldolase
  • 51269 - AFP III-like domain
  • 0Direct
    48439,49594
  • 48439 - Protein prenylyltransferase
  • 49594 - Rab geranylgeranyltransferase alpha-subunit, insert domain
  • 0Direct
    55973,55973
  • 55973 - S-adenosylmethionine synthetase
  • 55973 - S-adenosylmethionine synthetase
  • 0Direct
    52540,52540
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    51569,53223
  • 51569 - Aldolase
  • 53223 - Aminoacid dehydrogenase-like, N-terminal domain
  • 0Direct
    -9,51569
  • -9 - PDB
  • 51569 - Aldolase
  • 0Direct
    56176,55103
  • 56176 - FAD-binding/transporter-associated domain-like
  • 55103 - FAD-linked oxidases, C-terminal domain
  • 0.00001168Direct
    55620,55083
  • 55620 - Tetrahydrobiopterin biosynthesis enzymes-like
  • 55083 - 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, HPPK
  • 0.00002024Direct
    53223,51735
  • 53223 - Aminoacid dehydrogenase-like, N-terminal domain
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 0.0002334Direct
    55620,55620
  • 55620 - Tetrahydrobiopterin biosynthesis enzymes-like
  • 55620 - Tetrahydrobiopterin biosynthesis enzymes-like
  • 0.01753Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    55205,52540,51569
  • 55205 - EPT/RTPC-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 51569 - Aldolase
  • 0Direct
    51569,53223,51735
  • 51569 - Aldolase
  • 53223 - Aminoacid dehydrogenase-like, N-terminal domain
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 0Direct
    52540,51569,53223
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 51569 - Aldolase
  • 53223 - Aminoacid dehydrogenase-like, N-terminal domain
  • 0Direct
    55620,55083,51717
  • 55620 - Tetrahydrobiopterin biosynthesis enzymes-like
  • 55083 - 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, HPPK
  • 51717 - Dihydropteroate synthetase-like
  • 0Direct
    48439,49594,52075
  • 48439 - Protein prenylyltransferase
  • 49594 - Rab geranylgeranyltransferase alpha-subunit, insert domain
  • 52075 - Outer arm dynein light chain 1
  • 0Direct
    55620,55620,55083
  • 55620 - Tetrahydrobiopterin biosynthesis enzymes-like
  • 55620 - Tetrahydrobiopterin biosynthesis enzymes-like
  • 55083 - 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, HPPK
  • 0Direct
    55973,55973,55973
  • 55973 - S-adenosylmethionine synthetase
  • 55973 - S-adenosylmethionine synthetase
  • 55973 - S-adenosylmethionine synthetase
  • 0Direct
    56796,55205,52540
  • 56796 - Dehydroquinate synthase-like
  • 55205 - EPT/RTPC-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
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