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Enzyme Commission (EC): Hydrolases

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Root: EC Hierarchy (from IntEnz release 70)

Shortest distance to current term (+ for parents, - for children) EC term [EC ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ 1:   root [root] <7>
0:   Hydrolases [3] <13>(403|678) (402|422|208)
- 1:   Acting on ester bonds [3.1] <23>(158|227) (158|125|55)
- 1:   Acting on peptide bonds (peptidases) [3.4] <19>(114|168) (114|130|72)
- 1:   Acting on carbon-nitrogen bonds, other than peptide bonds [3.5] <6>(72|104) (72|40|18)
- 1:   Acting on acid anhydrides [3.6] <5>(106|134) (105|104|67)
- 1:   Glycosylases [3.2] <3>(67|118) (67|74|35)
- 1:   Acting on ether bonds [3.3] <2>(9|8) (9|6|2)
- 1:   Acting on halide bonds [3.8] <2>(3|3) (3|0|0)
- 1:   Acting on carbon-carbon bonds [3.7] <1>(9|10) (9|4|1)
- 1:   Acting on carbon-phosphorus bonds [3.11] <1>(2|2) (2|0|0)
- 1:   Acting on carbon-sulfur bonds [3.13] <1>(2|2) (2|0|0)
- 1:   Acting on phosphorus-nitrogen bonds [3.9] <1>(1|1) (1|0|0)
- 1:   Acting on sulfur-nitrogen bonds [3.10] <1>(0|0) (0|0|0)
- 1:   Acting on sulfur-sulfur bonds [3.12] <1>(0|0) (0|0|0)


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
Acetamidase/Formamidase-like0Direct
Ribonuclease H-like0Direct
DHH phosphoesterases0Direct
Isochorismatase-like hydrolases0Direct
alpha/beta-Hydrolases0Direct
(Phosphotyrosine protein) phosphatases II0Direct
beta-lactamase/transpeptidase-like0Direct
Carboxypeptidase regulatory domain-like0Direct
Pyrrolidone carboxyl peptidase (pyroglutamate aminopeptidase)0Direct
Peptidyl-tRNA hydrolase domain-like0Direct
Rof/RNase P subunit-like0Direct
Autotransporter0Direct
Type I dockerin domain0Direct
Putative cyclase0Direct
Anthrax protective antigen0Direct
Beta-galactosidase LacA, domain 30Direct
Arabinanase/levansucrase/invertase0Direct
JAB1/MPN domain0Direct
5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain0Direct
Blood coagulation inhibitor (disintegrin)0Direct
Flavivirus capsid protein C0Direct
Acid proteases0Direct
Glutaminase/Asparaginase0Direct
Peptidyl-tRNA hydrolase II0Direct
Sec63 N-terminal domain-like0Direct
Carbohydrate binding domain0Direct
"Winged helix" DNA-binding domain0Direct
Peptidyl-tRNA hydrolase-like0Direct
Complement control module/SCR domain0Direct
TMV-like viral coat proteins0Direct
Toprim domain0Direct
Urease, gamma-subunit0Direct
AF0625-like0Direct
Bacterial GAP domain0Direct
Concanavalin A-like lectins/glucanases0Direct
Hyaluronidase post-catalytic domain-like0Direct
CYTH-like phosphatases0Direct
EF-G C-terminal domain-like0Direct
Metallo-dependent hydrolases0Direct
HIT-like0Direct
DNA-binding domain of retroviral integrase0Direct
Carbohydrate-binding domain0Direct
Somatomedin B domain0Direct
Trefoil0Direct
(Trans)glycosidases0Direct
Dextranase, N-terminal domain0Direct
Penicillin-binding protein associated domain0Direct
Glycoside hydrolase/deacetylase0Direct
dsRNA-binding domain-like0Direct
Creatinase/aminopeptidase0Direct
Influenza hemagglutinin (stalk)0Direct
Pectin lyase-like0Direct
STI-like0Direct
Carbohydrate phosphatase0Direct
Glycosyl hydrolase domain0Direct
Saposin0Direct
D-aminopeptidase, middle and C-terminal domains0Direct
N-acetylmuramoyl-L-alanine amidase-like0Direct
Chitinase insertion domain0Direct
PLC-like phosphodiesterases0Direct
RNase III domain-like0Direct
Phage fibre proteins0Direct
EndoU-like0Direct
Creatinase/prolidase N-terminal domain0Direct
ClpP/crotonase0Direct
Cdc48 domain 2-like0Direct
Carbon-nitrogen hydrolase0Direct
Viral protein domain0Direct
AbfB domain0Direct
Rnp2-like0Direct
Viral glycoprotein, central and dimerisation domains0Direct
Viral leader polypeptide zinc finger0Direct
Cystatin/monellin0Direct
TSP-1 type 1 repeat0Direct
Class I glutamine amidotransferase-like0Direct
Coronavirus NSP7-like0Direct
Cellulose-binding domain0Direct
Protein serine/threonine phosphatase 2C, C-terminal domain0Direct
Retroviral matrix proteins0Direct
Archaeal IMP cyclohydrolase PurO0Direct
Acylphosphatase/BLUF domain-like0Direct
HRDC-like0Direct
DNA helicase RuvA subunit, C-terminal domain0Direct
Collagen-binding domain0Direct
Retrovirus zinc finger-like domains0Direct
AlbA-like0Direct
Zn-dependent exopeptidases0Direct
N-terminal domain of MutM-like DNA repair proteins0Direct
Sialidases0Direct
Ribosome inactivating proteins (RIP)0Direct
N-terminal nucleophile aminohydrolases (Ntn hydrolases)0Direct
Methylesterase CheB, C-terminal domain0Direct
EGF/Laminin0Direct
Heat shock protein 70kD (HSP70), C-terminal subdomain0Direct
PP2C-like0Direct
Cellulose docking domain, dockering0Direct
Dipeptidyl peptidase I (cathepsin C), exclusion domain0Direct
Transferrin receptor-like dimerisation domain0Direct
Retrovirus capsid dimerization domain-like0Direct
Leukotriene A4 hydrolase N-terminal domain0Direct
SPOC domain-like0Direct
Uracil-DNA glycosylase-like0Direct
Retrovirus capsid protein, N-terminal core domain0Direct
DNA primase core0Direct
Sulfolobus fructose-1,6-bisphosphatase-like0Direct
LmbE-like0Direct
Creatininase0Direct
Plant lectins/antimicrobial peptides0Direct
dUTPase-like0Direct
Peptidylarginine deiminase Pad4, middle domain0Direct
Spermadhesin, CUB domain0Direct
DPP6 N-terminal domain-like0Direct
Families 57/38 glycoside transferase middle domain0Direct
BRK domain-like0Direct
OMPT-like0Direct
DTD-like0Direct
Rhomboid-like0Direct
Microbial ribonucleases0Direct
ITPase-like0Direct
Inorganic pyrophosphatase0Direct
RuvA domain 2-like0Direct
Ribonuclease Rh-like0Direct
Pentein0Direct
Peptide deformylase0Direct
Aminoacid dehydrogenase-like, N-terminal domain0Direct
Subtilisin-like0Direct
Nucleoside hydrolase0Direct
CbiG N-terminal domain-like0Direct
L9 N-domain-like0Direct
Cap-Gly domain0Direct
HisI-like0Direct
CinA-like0Direct
Plant invertase/pectin methylesterase inhibitor0Direct
P-loop containing nucleoside triphosphate hydrolases0Direct
PGBD-like0Direct
Sec-C motif0Direct
Galactose-binding domain-like0Direct
Origin of replication-binding domain, RBD-like0Direct
beta-N-acetylhexosaminidase-like domain0Direct
RibA-like0Direct
Invertebrate chitin-binding proteins0Direct
SurE-like0Direct
Type X cellulose binding domain, CBDX0Direct
RNase A-like0Direct
beta-Galactosidase/glucuronidase domain0Direct
SGNH hydrolase0Direct
HybD-like0Direct
Initiation factor IF2/eIF5b, domain 30Direct
Kazal-type serine protease inhibitors0Direct
Apyrase0Direct
Cysteine proteinases0Direct
C-terminal domain of PLC-beta0Direct
Positive stranded ssRNA viruses0Direct
Transthyretin (synonym: prealbumin)0Direct
Protease propeptides/inhibitors0Direct
Glycosyl hydrolases family 6, cellulases0Direct
Voltage-gated potassium channels0Direct
MCP/YpsA-like0Direct
Urease, beta-subunit0Direct
Purple acid phosphatase, N-terminal domain0Direct
GroEL equatorial domain-like0Direct
cAMP-binding domain-like0Direct
His-Me finger endonucleases0Direct
LD-carboxypeptidase A C-terminal domain-like0Direct
Nitrous oxide reductase, N-terminal domain0Direct
Putative isomerase YbhE0Direct
Methylglyoxal synthase-like0Direct
Tetrahydrobiopterin biosynthesis enzymes-like0Direct
Hemopexin-like domain0Direct
Restriction endonuclease-like0Direct
all-alpha NTP pyrophosphatases0Direct
Hedgehog/DD-peptidase0Direct
Phospholipase C/P1 nuclease0Direct
Six-hairpin glycosidases0Direct
NSP3A-like0Direct
DNA/RNA polymerases0Direct
Lysozyme-like0Direct
Holliday junction resolvase RusA0Direct
Prokaryotic SH3-related domain0Direct
Acid phosphatase/Vanadium-dependent haloperoxidase0Direct
Formate/glycerate dehydrogenase catalytic domain-like0Direct
Fumarylacetoacetate hydrolase, FAH, N-terminal domain0Direct
C-terminal domain of Ku800Direct
Metallo-dependent phosphatases0Direct
SpoIIaa-like0Direct
LexA/Signal peptidase0Direct
SARS Nsp1-like0Direct
Composite domain of metallo-dependent hydrolases0Direct
LigT-like0Direct
SEA domain0Direct
Rap30/74 interaction domains0Direct
GLA-domain0Direct
PDZ domain-like0Direct
Herpes virus serine proteinase, assemblin0Direct
CheY-like0Direct
CNF1/YfiH-like putative cysteine hydrolases0Direct
Dcp2 domain-like0Direct
ADP-ribosylglycohydrolase0Direct
CobE/GbiG C-terminal domain-like0Direct
AN1-like Zinc finger0Direct
PKD domain0Direct
Metallo-hydrolase/oxidoreductase0Direct
Phospholipase A2, PLA20Direct
DNase I-like0Direct
XseB-like0Direct
Coronavirus NSP8-like0Direct
R3H domain0Direct
Nudix0Direct
CRAL/TRIO N-terminal domain0Direct
Seven-hairpin glycosidases0Direct
S13-like H2TH domain0Direct
Outer membrane phospholipase A (OMPLA)0Direct
Kringle-like0Direct
Macro domain-like0Direct
ComB-like0Direct
Clostridium neurotoxins, "coiled-coil" domain0Direct
FabD/lysophospholipase-like0Direct
Thermostable phytase (3-phytase)0Direct
DUSP-like0Direct
N-terminal Zn binding domain of HIV integrase0Direct
Oligoxyloglucan reducing end-specific cellobiohydrolase0Direct
X-Prolyl dipeptidyl aminopeptidase PepX, N-terminal domain0Direct
Coronavirus NSP10-like0Direct
Glucocorticoid receptor-like (DNA-binding domain)0Direct
Replicase NSP90Direct
HAD-like0Direct
Caspase-like0Direct
Sortase0Direct
Aminopeptidase/glucanase lid domain0Direct
Calpain large subunit, middle domain (domain III)0Direct
Methenyltetrahydromethanopterin cyclohydrolase0Direct
Soluble domain of poliovirus core protein 3a0Direct
PAZ domain0Direct
Beta-D-glucan exohydrolase, C-terminal domain0Direct
N-terminal domain of DnaB helicase0Direct
Arginase/deacetylase0Direct
Heat shock protein 70kD (HSP70), peptide-binding domain0Direct
Peptidase/esterase 'gauge' domain0Direct
mRNA decapping enzyme DcpS N-terminal domain0Direct
Bacterial exopeptidase dimerisation domain0Direct
Penicillin binding protein dimerisation domain0Direct
Galactose mutarotase-like0Direct
ssDNA viruses0Direct
Trypsin-like serine proteases0Direct
Invasin/intimin cell-adhesion fragments0Direct
C2 domain (Calcium/lipid-binding domain, CaLB)0Direct
Metalloproteases ("zincins"), catalytic domain0Direct
Cytidine deaminase-like0Direct
Xylose isomerase-like5.057e-16Direct
PH domain-like5.057e-16Direct
E set domains0.00000000000000299Direct
HD-domain/PDEase-like0.000000000000004965Direct
vWA-like0.000000000000007911Direct
Calcium-dependent phosphotriesterase0.00000000000002491Direct
LysM domain0.00000000000004996Direct
EF-hand0.0000000000001147Direct
Translation proteins0.0000000000006408Direct
EAL domain-like0.0000000000007243Direct
Purine and uridine phosphorylases0.000000000001481Direct
Phosphotyrosine protein phosphatases I0.00000000005508Direct
Ribosomal protein S5 domain 2-like0.0000000001148Direct
Staphylococcal nuclease0.000000001016Direct
PA domain0.000000001058Direct
Ubiquitin-like0.000000001834Direct
UBA-like0.000000009654Direct
Hairpin loop containing domain-like0.00000002064Direct
GAF domain-like0.00000006352Direct
LDL receptor-like module0.00000009225Direct
YjgF-like0.0000001211Direct
Tudor/PWWP/MBT0.0000001238Direct
DEATH domain0.0000001487Direct
Phospholipase D/nuclease0.0000001646Direct
Lipase/lipooxygenase domain (PLAT/LH2 domain)0.0000006854Direct
Fibronectin type III0.0000007054Direct
Starch-binding domain-like0.000001645Direct
N-(deoxy)ribosyltransferase-like0.000002098Direct
NagB/RpiA/CoA transferase-like0.000005335Direct
beta-Roll0.000006177Direct
PUG domain-like0.000007874Direct
Phosphoglycerate mutase-like0.00001103Direct
CBD9-like0.00002279Direct
DNA clamp0.00002279Direct
HCP-like0.00002945Direct
DEK C-terminal domain0.00003386Direct
PH0987 N-terminal domain-like0.0001087Direct
HIT/MYND zinc finger-like0.0001093Direct
FnI-like domain0.0002845Direct
Hedgehog/intein (Hint) domain0.0003774Direct
Barwin-like endoglucanases0.0003963Direct
GroEL-intermediate domain like0.0005188Direct
Ricin B-like lectins0.0005811Direct
Chromo domain-like0.0007097Direct
SRCR-like0.001031Inherited
GTPase activation domain, GAP0.001943Inherited
Cell wall binding repeat0.002004Inherited
Ras GEF0.002482Inherited
WD40 repeat-like0.002675Inherited
SAP domain0.003544Inherited
Integrin alpha N-terminal domain0.004724Inherited
FAH0.007575Inherited
PX domain0.008736Inherited
F-box domain0.009914Inherited
GroEL apical domain-like0.01646Inherited
Rhodanese/Cell cycle control phosphatase0.01832Inherited
RNA-binding domain, RBD0.01903Inherited
Chaperone J-domain0.02436Inherited
MIT domain0.02605Inherited
DNA-glycosylase0.0295Inherited
Second domain of FERM0.03488Inherited
Homing endonucleases0.03671Inherited
Duplicated hybrid motif0.03817Inherited
SCOP hierarchy in SUPERFAMILY0.04573Inherited
C-terminal (heme d1) domain of cytochrome cd1-nitrite reductase0.047Inherited
PHP domain-like0.06248Inherited
SMAD/FHA domain0.09674Inherited
Ran binding protein zinc finger-like0.1038Inherited
TATA-box binding protein-like0.1164Inherited
HSP20-like chaperones0.1483Inherited
YrdC/RibB0.151Inherited
CRAL/TRIO domain0.1613Inherited
TRAF domain-like0.275Inherited
HMA, heavy metal-associated domain0.275Inherited
NTF2-like0.2859Inherited
Ankyrin repeat0.456Inherited
Non-globular alpha+beta subunits of globular proteins0.6064Inherited
post-AAA+ oligomerization domain-like0.6562Inherited
ABC transporter transmembrane region0.7644Inherited
Prokaryotic type I DNA topoisomerase0.8356Inherited
PUA domain-like0.8874Inherited
Heme oxygenase-like0.9058Inherited
S15/NS1 RNA-binding domain0.9345Inherited
Kelch motif0.9692Inherited
Bromodomain0.9864Inherited
Thiamin diphosphate-binding fold (THDP-binding)1Inherited
PYP-like sensor domain (PAS domain)1Inherited
Metal cation-transporting ATPase, ATP-binding domain N1Inherited
PreATP-grasp domain1Inherited
Cupredoxins1Inherited
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase1Inherited
NAD(P)-binding Rossmann-fold domains1Inherited
Bet v1-like1Inherited
SH3-domain1Inherited
Carbamoyl phosphate synthetase, large subunit connection domain1Inherited
Nucleic acid-binding proteins1Inherited
LDH C-terminal domain-like1Inherited
Inosine monophosphate dehydrogenase (IMPDH)1Inherited
DNA ligase/mRNA capping enzyme, catalytic domain1Inherited
PHP14-like1Inherited
Acyl-CoA N-acyltransferases (Nat)1Inherited
TPR-like1Inherited
Class II aaRS ABD-related1Inherited
TGS-like1Inherited
Thioredoxin-like1Inherited
Nucleotide cyclase1Inherited
FMT C-terminal domain-like1Inherited
PLP-dependent transferases1Inherited
ACP-like1Inherited
GroES-like1Inherited
FYVE/PHD zinc finger1Inherited
ACT-like1Inherited
AraD/HMP-PK domain-like1Inherited
CCCH zinc finger1Inherited
Terpenoid cyclases/Protein prenyltransferases1Inherited
SH2 domain1Inherited
Aspartate/ornithine carbamoyltransferase1Inherited
Cyclophilin-like1Inherited
PIN domain-like1Inherited
Quinoprotein alcohol dehydrogenase-like1Inherited
L30e-like1Inherited
Nucleotidyltransferase1Inherited
UDP-Glycosyltransferase/glycogen phosphorylase1Inherited
Thiolase-like1Inherited
Periplasmic binding protein-like II1Inherited
ADC-like1Inherited
Probable ACP-binding domain of malonyl-CoA ACP transacylase1Inherited
LuxS/MPP-like metallohydrolase1Inherited
Alkaline phosphatase-like1Inherited
Methylated DNA-protein cysteine methyltransferase, C-terminal domain1Inherited
Immunoglobulin1Inherited
Carbonic anhydrase1Inherited
S-adenosyl-L-methionine-dependent methyltransferases1Inherited
beta-carbonic anhydrase, cab1Inherited
Thioesterase/thiol ester dehydrase-isomerase1Inherited
Dihydrofolate reductase-like1Inherited
WW domain1Inherited
Tryptophan synthase beta subunit-like PLP-dependent enzymes1Inherited
Terpenoid synthases1Inherited
Actin-like ATPase domain1Inherited
Phosphoenolpyruvate/pyruvate domain1Inherited
ARM repeat1Inherited
Calcium ATPase, transduction domain A1Inherited
Carbamoyl phosphate synthetase, small subunit N-terminal domain1Inherited
ADP-ribosylation1Inherited
Amidase signature (AS) enzymes1Inherited
Growth factor receptor domain1Inherited
L domain-like1Inherited
RmlC-like cupins1Inherited
SAM/Pointed domain1Inherited
Clavaminate synthase-like1Inherited
DHS-like NAD/FAD-binding domain1Inherited
Formyltransferase1Inherited
RING/U-box1Inherited
Calcium ATPase, transmembrane domain M1Inherited


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Family

(show details)
SCOP termFDR (all)Annotation (direct or inherited)
Succinylarginine dihydrolase-like0Direct
Hydantoinase (dihydropyrimidinase)0Direct
Fibronectin type II module0Direct
CobE/GbiG C-terminal domain-like0Direct
MazG-like0Direct
tRNA splicing product Appr>p cyclic nucleotide phosphodiesterase0Direct
Ku80 subunit N-terminal domain0Direct
Holliday junction resolvase RusA0Direct
Nuclease0Direct
HtrA-like serine proteases0Direct
ComB-like0Direct
Plant cytotoxins0Direct
Urease, gamma-subunit0Direct
Adenosine/AMP deaminase0Direct
DEATH effector domain, DED0Direct
Glycosyl hydrolases family 32 N-terminal domain0Direct
Ubiquitin carboxyl-terminal hydrolase, UCH0Direct
ATP-dependent protease Lon (La), catalytic domain0Direct
alpha-mannosidase, domain 20Direct
RNase P protein0Direct
alpha-mannosidase0Direct
LD-carboxypeptidase A C-terminal domain-like0Direct
Maf-like0Direct
X-Prolyl dipeptidyl aminopeptidase PepX, N-terminal domain0Direct
SARS Nsp1-like0Direct
CinA-like0Direct
Chitosanase0Direct
S-adenosylhomocystein hydrolase0Direct
Replicase NSP90Direct
Zn metallo-beta-lactamase0Direct
Retrovirus capsid protein, N-terminal core domain0Direct
Glutaminase0Direct
Viral cysteine protease of trypsin fold0Direct
SGL-like0Direct
Glycerophosphoryl diester phosphodiesterase0Direct
alpha-D-glucuronidase/Hyaluronidase catalytic domain0Direct
R3H domain0Direct
PKD domain0Direct
Isochorismatase-like hydrolases0Direct
DNA helicase RuvA subunit, C-terminal domain0Direct
alpha-Amylases, C-terminal beta-sheet domain0Direct
Macro domain0Direct
Invasin/intimin cell-adhesion fragments0Direct
Tetrahydrofolate dehydrogenase/cyclohydrolase0Direct
Colipase-binding domain0Direct
Reverse transcriptase0Direct
Mason-Pfizer monkey virus matrix protein0Direct
LamB/YcsF-like0Direct
Porphyromonas-type peptidylarginine deiminase0Direct
DNA helicase RuvA subunit, N-terminal domain0Direct
M48USP-like0Direct
Amylase, catalytic domain0Direct
Hyaluronidase N-terminal domain-like0Direct
Creatinase/aminopeptidase0Direct
Vertebrate phospholipase A20Direct
RecG "wedge" domain0Direct
Penicillin binding protein dimerisation domain0Direct
Kringle modules0Direct
Mammalian PLC0Direct
Astacin0Direct
Prokaryotic proteases0Direct
NlpC/P600Direct
Ubiquitin thiolesterase protein OTUB2 (Otubain-2)0Direct
Sec-C motif0Direct
Carboxypeptidase T0Direct
mRNA triphosphatase CET10Direct
Virulence effector SptP domain0Direct
Purple acid phosphatase-like0Direct
NADH pyrophosphatase0Direct
TAP-like0Direct
Pepsin-like0Direct
mRNA cap methylase0Direct
Dipeptidyl peptidase I (cathepsin C), exclusion domain0Direct
Beta-galactosidase LacA, domain 30Direct
Clostridium neurotoxins, catalytic domain0Direct
N-acetylmuramoyl-L-alanine amidase-like0Direct
Alpha-L-arabinofuranosidase B, N-terminal domain0Direct
Enolase-phosphatase E10Direct
GroEL-like chaperone, intermediate domain0Direct
Retroviral integrase, catalytic domain0Direct
CRAL/TRIO domain0Direct
Glycosyl hydrolases family 32 C-terminal domain0Direct
Achaeal helicase C-terminal domain0Direct
Patatin0Direct
SAH/MTA deaminase-like0Direct
Leucine aminopeptidase (Aminopeptidase A), N-terminal domain0Direct
PBP5 C-terminal domain-like0Direct
C-terminal, Zn-finger domain of MutM-like DNA repair proteins0Direct
N-acetylglucosamine-6-phosphate deacetylase, NagA0Direct
Putative isomerase YbhE0Direct
Bacterial GAP domain0Direct
Plant invertase/pectin methylesterase inhibitor0Direct
CheD-like0Direct
Mug-like0Direct
RecQ helicase DNA-binding domain-like0Direct
Beta-galactosidase LacA, domain 20Direct
AglA-like glucosidase0Direct
Nucleoside hydrolase0Direct
PDEase0Direct
beta-N-acetylhexosaminidase catalytic domain0Direct
LmbE-like0Direct
Peptidyl-tRNA hydrolase domain0Direct
SEA domain0Direct
HisE-like (PRA-PH)0Direct
N-terminal Zn binding domain of HIV integrase0Direct
MgsA/YrvN C-terminal domain-like0Direct
Transferrin receptor-like dimerisation domain0Direct
Cellulose-binding domain family III0Direct
DPP6 catalytic domain-like0Direct
DNA-binding domain from rap300Direct
Toprim domain0Direct
Putative serine hydrolase Ydr428c0Direct
Epoxide hydrolase0Direct
Soluble domain of poliovirus core protein 3a0Direct
LexA repressor, N-terminal DNA-binding domain0Direct
Phage lysozyme0Direct
beta-Phosphoglucomutase-like0Direct
Rhomboid-like0Direct
Oligoxyloglucan reducing end-specific cellobiohydrolase0Direct
PepX C-terminal domain-like0Direct
Putative alpha-L-fucosidase, catalytic domain0Direct
2',3'-cyclic nucleotide 3'-phosphodiesterase, catalytic domain0Direct
Cellulose docking domain, dockering0Direct
Deoxycytidylate deaminase-like0Direct
Parvoviridae-like VP0Direct
Viral leader polypeptide zinc finger0Direct
Aspartyl dipeptidase PepE0Direct
Initiation factor IF2/eIF5b, domain 30Direct
Bacterial chitobiase, n-terminal domain0Direct
Dimethylarginine dimethylaminohydrolase DDAH0Direct
Protein serine/threonine phosphatase0Direct
ITPase (Ham1)0Direct
AN1-like Zinc finger0Direct
Calpain large subunit, middle domain (domain III)0Direct
Type X cellulose binding domain, CBDX0Direct
TIP49 domain0Direct
Hemagglutinin domain of haemagglutinin-esterase-fusion glycoprotein HEF10Direct
Cutinase-like0Direct
UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase LpxC0Direct
Methionine aminopeptidase, insert domain0Direct
RNB domain-like0Direct
Retroviral protease (retropepsin)0Direct
NLI interacting factor-like phosphatase0Direct
Clostridium neurotoxins, C-terminal domain0Direct
GpdQ-like0Direct
Pancreatic carboxypeptidases0Direct
Composite domain of glycosyl hydrolase families 5, 30, 39 and 510Direct
Helicase-like "domain" of reverse gyrase0Direct
Replication initiation protein E10Direct
RNA-dependent RNA-polymerase0Direct
Type I dockerin domain0Direct
Clp protease, ClpP subunit0Direct
SurE-like0Direct
(Glycosyl)asparaginase0Direct
Pectin methylesterase0Direct
Archaeal IMP cyclohydrolase PurO0Direct
Glycosyl Hydrolase Family 880Direct
Zf-UBP0Direct
G-type lysozyme0Direct
Alkaline phosphatase0Direct
Family 9 carbohydrate-binding module, CBD90Direct
AF0625-like0Direct
Ku70 subunit N-terminal domain0Direct
beta-Lactamase/D-ala carboxypeptidase0Direct
Peptide deformylase0Direct
Hydantoinase (dihydropyrimidinase), catalytic domain0Direct
BRK domain-like0Direct
Serine-carboxyl proteinase, SCP0Direct
EGF-type module0Direct
Prolyl oligopeptidase, C-terminal domain0Direct
NPCBM-like0Direct
Nsp15 C-terminal domain-like0Direct
Outer membrane protease OMPT0Direct
Prolyl oligopeptidase, N-terminal domain0Direct
MMP N-terminal domain0Direct
Peptidyl-tRNA hydrolase-like0Direct
HRDC domain from helicases0Direct
Putative acetylxylan esterase-like0Direct
Coronavirus NSP8-like0Direct
LD-carboxypeptidase A N-terminal domain-like0Direct
Pyrimidine 5'-nucleotidase (UMPH-1)0Direct
Actin/HSP700Direct
Beta-galactosidase LacA, domains 4 and 50Direct
Leucine aminopeptidase, C-terminal domain0Direct
MPP-like0Direct
RNA helicase0Direct
Proline iminopeptidase-like0Direct
Ppx associated domain0Direct
TMV-like viral coat proteins0Direct
FolH catalytic domain-like0Direct
Inositol monophosphatase/fructose-1,6-bisphosphatase-like0Direct
Putative glucosidase YicI, domain 30Direct
Serine carboxypeptidase-like0Direct
NagZ-like0Direct
Dextranase, N-terminal domain0Direct
Insect phospholipase A20Direct
Ribonuclease H0Direct
Dcp2 box A domain0Direct
Neurolysin-like0Direct
ADP ribosyl cyclase-like0Direct
Class II viral fusion proteins C-terminal domain0Direct
Class B acid phosphatase, AphA0Direct
Lysophospholipase0Direct
PA1517-like0Direct
Sec63 C-terminal domain-like0Direct
Ribonuclease A-like0Direct
Coronavirus NSP10-like0Direct
Peptidylarginine deiminase Pad4, N-terminal domain0Direct
Peptidyl-tRNA hydrolase II0Direct
MMLV matrix protein-like0Direct
Methenyltetrahydromethanopterin cyclohydrolase0Direct
Bacterial dinuclear zinc exopeptidases0Direct
Prohormone convertase 1 pro-domain0Direct
Elongation factors0Direct
Type 2 phosphatidic acid phosphatase, PAP20Direct
Heat shock protein 70kD (HSP70), C-terminal subdomain0Direct
Ku80 subunit middle domain0Direct
Peptidoglycan binding domain, PGBD0Direct
Type II chitinase0Direct
GRAM domain0Direct
D-aminoacylase0Direct
beta-N-acetylhexosaminidase domain0Direct
Sortase0Direct
Exodeoxyribonuclease V beta chain (RecC), C-terminal domain0Direct
N-terminal domain of MutM-like DNA repair proteins0Direct
Acetylcholinesterase-like0Direct
alpha-L-arabinanase-like0Direct
Matrix metalloproteases, catalytic domain0Direct
Cdc48 domain 2-like0Direct
MutY C-terminal domain-like0Direct
Glutaminase/Asparaginase0Direct
Uracil-DNA glycosylase0Direct
Hyaluronidase post-catalytic domain-like0Direct
Subtilase propeptides/inhibitors0Direct
N-acetylmuramoyl-L-alanine amidase-like0Direct
RNase D C-terminal domains0Direct
HAD-related0Direct
CBM4/90Direct
Aminoacid dehydrogenase-like, C-terminal domain0Direct
Integrin A (or I) domain0Direct
Nodaviridae-like VP0Direct
Rap30/74 interaction domains0Direct
Cytidine deaminase0Direct
Histidine acid phosphatase0Direct
Cap-Gly domain0Direct
Sphingomyelin phosphodiesterase-like0Direct
PLC-like (P variant)0Direct
Integrin alpha N-terminal domain0Direct
5' nucleotidase-like0Direct
Magnesium-dependent phosphatase-1, Mdp10Direct
alpha-subunit of urease, catalytic domain0Direct
Allantoicase repeat0Direct
Coronavirus NSP7-like0Direct
Class I glutamine amidotransferases (GAT)0Direct
Creatinase/prolidase N-terminal domain0Direct
4HBT-like0Direct
Sec63 N-terminal domain0Direct
RNase III catalytic domain-like0Direct
Beta-D-glucan exohydrolase, C-terminal domain0Direct
Type 1 signal peptidase0Direct
GLA-domain0Direct
EF-G/eEF-2 domains III and V0Direct
Phosphotriesterase-like0Direct
Bacterial exopeptidase dimerisation domain0Direct
LexA-related0Direct
Acyl-CoA thioesterase0Direct
Bee venom hyaluronidase0Direct
Exodeoxyribonuclease V beta chain (RecB), C-terminal domain0Direct
DPP6 N-terminal domain-like0Direct
Collagen-binding domain0Direct
Pancreatic lipase, N-terminal domain0Direct
FMDV leader protease0Direct
Somatomedin B domain0Direct
Phosphonoacetaldehyde hydrolase-like0Direct
Myotubularin-like phosphatases0Direct
MoCo carrier protein-like0Direct
Trypanosoma sialidase, C-terminal domain0Direct
Ppx/GppA phosphatase0Direct
P1 nuclease0Direct
Peptidylarginine deiminase Pad4, middle domain0Direct
GlpX-like bacterial fructose-1,6-bisphosphatase0Direct
CheY-related0Direct
Methylesterase CheB, C-terminal domain0Direct
3-methyladenine DNA glycosylase (AAG, ANPG, MPG)0Direct
2'-5' RNA ligase LigT0Direct
beta-Galactosidase, domain 50Direct
Viral proteases0Direct
RNase P subunit p300Direct
Picornaviridae-like VP (VP1, VP2, VP3 and VP4)0Direct
Zinc protease0Direct
YicI catalytic domain-like0Direct
Sulfolobus fructose-1,6-bisphosphatase-like0Direct
C-type lysozyme0Direct
Endonuclease I0Direct
Fibronectin type I module0Direct
Gingipain R (RgpB), C-terminal domain0Direct
AbfB domain0Direct
HTLV-II matrix protein0Direct
Gastric lipase0Direct
mRNA decapping enzyme DcpS N-terminal domain0Direct
Virulence factor P.69 pertactin0Direct
YihX-like0Direct
Urease, beta-subunit0Direct
Phosphoserine phosphatase0Direct
PepX catalytic domain-like0Direct
PP2C-like0Direct
1,4-beta-N-acetylmuraminidase0Direct
PUD-like0Direct
GTP cyclohydrolase I0Direct
EAL domain0Direct
Peptidylarginine deiminase Pad4, catalytic C-terminal domain0Direct
ADP-ribosylglycohydrolase0Direct
Class I alpha-1;2-mannosidase, catalytic domain0Direct
Complement control module/SCR domain0Direct
Histone deacetylase, HDAC0Direct
Hypothetical esterase YJL068C0Direct
Bacterial ribonucleases0Direct
alpha-Subunit of urease0Direct
Fungal lipases0Direct
NodB-like polysaccharide deacetylase0Direct
XPF/Rad1/Mus81 nuclease0Direct
Chitinase insertion domain0Direct
Herpes virus serine proteinase, assemblin0Direct
RNase P subunit p29-like0Direct
Leukotriene A4 hydrolase N-terminal domain0Direct
Thermostable phytase (3-phytase)0Direct
Predicted hydrolases Cof0Direct
Thioesterases0Direct
Carboxypeptidase regulatory domain0Direct
Glycosyl hydrolases family 35 catalytic domain0Direct
mRNA decapping enzyme DcpS C-terminal domain0Direct
Blood coagulation inhibitor (disintegrin)0Direct
Renal dipeptidase0Direct
Dienelactone hydrolase0Direct
mRNA decapping enzyme-like0Direct
Endonuclease IV0Direct
HisI-like0Direct
NagD-like0Direct
Spermadhesin, CUB domain0Direct
alpha-D-glucuronidase, N-terminal domain0Direct
Trehalase-like0Direct
Purple acid phosphatase, N-terminal domain0Direct
Transthyretin (synonym: prealbumin)0Direct
D-aminopeptidase, middle and C-terminal domains0Direct
5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain0Direct
Acylphosphatase-like0Direct
Trefoil0Direct
CBM220Direct
N-acetylglucosamine-6-phosphate deacetylase, NagA, catalytic domain0Direct
Tail specific protease, catalytic domain0Direct
DNA replication initiator (cdc21/cdc54) N-terminal domain0Direct
YlbA-like0Direct
Flavivirus capsid protein C0Direct
GroEL-like chaperone, apical domain0Direct
Apyrase0Direct
Inositol polyphosphate 5-phosphatase (IPP5)0Direct
Family 28 carbohydrate binding module, CBM280Direct
RibA-like0Direct
AstE/AspA-like0Direct
GW domain0Direct
Glyoxalase II (hydroxyacylglutathione hydrolase)0Direct
Nsp15 N-terminal domain-like0Direct
Subtilases0Direct
alpha-mannosidase, C-terminal domain0Direct
Leishmanolysin0Direct
Dihydroorotase0Direct
Caspase catalytic domain0Direct
Adenain-like0Direct
Inorganic pyrophosphatase0Direct
Penicillin acylase, catalytic domain0Direct
Hevein-like agglutinin (lectin) domain0Direct
CBM110Direct
Esterase domain of haemagglutinin-esterase-fusion glycoprotein HEF10Direct
Acetamidase/Formamidase-like0Direct
DNA/RNA non-specific endonuclease0Direct
Clostridium neurotoxins, the second last domain0Direct
D-aminoacylase, catalytic domain0Direct
Aminopeptidase/glucanase lid domain0Direct
5'-nucleotidase (syn. UDP-sugar hydrolase), N-terminal domain0Direct
Glycosyl hydrolases family 6, cellulases0Direct
Fungal zinc peptidase0Direct
Calpain large subunit, catalytic domain (domain II)0Direct
Esterase0Direct
Phosphonoacetate hydrolase0Direct
DUSP, domain in ubiquitin-specific proteases0Direct
Eukaryotic proteases0Direct
Leukotriene A4 hydrolase catalytic domain0Direct
dUTPase-like0Direct
Protein serine/threonine phosphatase 2C, C-terminal domain0Direct
AICAR transformylase domain of bifunctional purine biosynthesis enzyme ATIC0Direct
Manganese-dependent inorganic pyrophosphatase (family II)0Direct
Beta-D-xylosidase C-terminal domain-like0Direct
Xylanase/endoglucanase 11/120Direct
G proteins0Direct
Carboxylesterase0Direct
Formate/glycerate dehydrogenases, NAD-domain0Direct
Staphopain B, prodomain0Direct
Heat shock protein 70kD (HSP70), peptide-binding domain0Direct
DNA-binding domain of retroviral integrase0Direct
Retrovirus zinc finger-like domains0Direct
DTD-like0Direct
YicI N-terminal domain-like0Direct
Cellulose-binding domain family II0Direct
Glucoamylase0Direct
Dual specificity phosphatase-like0Direct
Immunodeficiency virus matrix proteins0Direct
Cell cycle control phosphatase, catalytic domain0Direct
Retrovirus capsid protein C-terminal domain0Direct
Imidazolonepropionase-like0Direct
PAZ domain0Direct
Ribonuclease Rh-like0Direct
RecU-like0Direct
GAG polyprotein M-domain0Direct
JAB1/MPN domain0Direct
Clostridium neurotoxins, "coiled-coil" domain0Direct
Trehalose-phosphatase0Direct
PA domain0Direct
beta-Galactosidase/glucuronidase, N-terminal domain0Direct
Histidinol phosphatase-like0Direct
LON domain-like0Direct
CAF1-like ribonuclease0Direct
MtnX-like0Direct
Bacterial lipase0Direct
Biotin biosynthesis protein BioH0Direct
VanX-like0Direct
Cellulose-binding domain0Direct
Z-DNA binding domain0Direct
C-terminal domain of Ku800Direct
Carbamilase0Direct
Dextranase, catalytic domain0Direct
N-terminal domain of RNase HI0Direct
Mismatch glycosylase0Direct
Double-stranded RNA-binding domain (dsRBD)0Direct
Family 19 glycosidase0Direct
Outer membrane phospholipase A (OMPLA)0Direct
Middle domain of MutM-like DNA repair proteins0Direct
XseB-like0Direct
Family 1 of glycosyl hydrolase0Direct
Glycosyl hydrolase family 7 catalytic core0Direct
Tandem AAA-ATPase domain0Direct
beta-glycanases0Direct
GroEL chaperone, ATPase domain0Direct
Hjc-like0Direct
DNA helicase RuvA subunit, middle domain0Direct
MutT-like0Direct
C-terminal domain of PLC-beta0Direct
TNF-alpha converting enzyme, TACE, catalytic domain0Direct
cAMP-binding domain0Direct
A4 beta-galactosidase middle domain0Direct
Extended AAA-ATPase domain0Direct
Germination protease0Direct
beta-Galactosidase/glucuronidase domain0Direct
YdjC-like0Direct
Inosicase0Direct
NSP3A-like0Direct
GUCT domain0Direct
NagB-like0Direct
Extended PAW domain0Direct
Sialidases (neuraminidases)0Direct
Influenza hemagglutinin (stalk)0Direct
Arginase-like amidino hydrolases0Direct
Ku70 subunit middle domain0Direct
Leukotriene A4 hydrolase C-terminal domain0Direct
Phospholipase C0Direct
Reprolysin-like0Direct
Janus/Ocnus0Direct
Putative cyclase0Direct
Penta-EF-hand proteins0Direct
Creatininase0Direct
Neutral endopeptidase (neprilysin)0Direct
Arginine deiminase0Direct
Hepsin, N-terminal domain0Direct
Proteasome subunits0Direct
CRAL/TRIO N-terminal domain0Direct
Thermolysin-like0Direct
Rpp14/Pop5-like0Direct
CbiG N-terminal domain-like0Direct
Dac-like0Direct
Alpha-toxin, C-terminal domain0Direct
Proprotein convertase P-domain0Direct
RuvC resolvase0Direct
Carbon-carbon bond hydrolase0Direct
Eng V-like0Direct
Galacturonase0Direct
Caliciviridae-like VP0Direct
Serum paraoxonase/arylesterase 1, PON10Direct
Ubiquitin carboxyl-terminal hydrolase UCH-L0Direct
Higher-molecular-weight phosphotyrosine protein phosphatases0Direct
Helicase DNA-binding domain0Direct
Shiga toxin, A-chain0Direct
Fungal ribonucleases0Direct
Pancreatic carboxypeptidase, activation domain0Direct
CDH-like0Direct
L30e/L7ae ribosomal proteins0Direct
NTF2-like0Direct
Staphylococcal nuclease0Direct
N-terminal domain of DnaB helicase0Direct
Nitrilase0Direct
Papain-like0Direct
SAH/MTA deaminase-like0Direct
Gamma-glutamyltranspeptidase-like0Direct
RNase Z-like0Direct
Hemopexin-like domain0Direct
Fumarylacetoacetate hydrolase, FAH, N-terminal domain0Direct
Cellulases catalytic domain0Direct
Carbohydrate binding domain0Direct
Imidazolonepropionase-like0Direct
Acylamino-acid-releasing enzyme, C-terminal donain0Direct
Cytosine deaminase catalytic domain0Direct
Gingipain R (RgpB), N-terminal domain0Direct
Arylsulfatase0Direct
Pyrrolidone carboxyl peptidase (pyroglutamate aminopeptidase)0Direct
ADPRibase-Mn-like0Direct
Serralysin-like metalloprotease, catalytic (N-terminal) domain0Direct
Acyl-ACP thioesterase-like0Direct
TSP-1 type 1 repeat0Direct
Cdc48 N-terminal domain-like0Direct
Family 17 carbohydrate binding module, CBM170Direct
Viral glycoprotein, central and dimerisation domains0Direct
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, phosphatase domain5.516e-16Direct
HD domain7.329e-16Direct
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, kinase domain0.000000000000003978Direct
Haloalkane dehalogenase0.00000000000000577Direct
MAM domain0.00000000000000577Direct
LysM domain0.00000000000004689Direct
DJ-1/PfpI0.0000000000001402Direct
EF-hand modules in multidomain proteins0.000000000000175Direct
Nitrous oxide reductase, N-terminal domain0.000000000003549Direct
Purine and uridine phosphorylases0.000000000006189Direct
Caspase recruitment domain, CARD0.00000000003018Direct
GAF domain0.00000000003352Direct
HIT (HINT, histidine triad) family of protein kinase-interacting proteins0.000000000345Direct
Low-molecular-weight phosphotyrosine protein phosphatases0.000000001157Direct
YjgF/L-PSP0.000000004095Direct
3,4-dihydroxy-2-butanone 4-phosphate synthase, DHBP synthase, RibB0.00000001434Direct
Chromo domain0.00000004048Direct
Tudor domain0.00000004703Direct
LDL receptor-like module0.00000008172Direct
HCP-like0.0000001828Direct
TENA/THI-40.0000003519Direct
CYTH domain0.0000004552Direct
Starch-binding domain0.0000005337Direct
Fibronectin type III0.000000865Direct
Acetylhydrolase0.0000008737Direct
Peptidoglycan hydrolase LytM0.0000008737Direct
Ubiquitin-related0.000004167Direct
Serralysin-like metalloprotease, C-terminal domain0.000005674Direct
PUG domain0.00000692Direct
Glycosyl hydrolases family 160.000008286Direct
phosphatase domain of polynucleotide kinase0.00001981Direct
UBA domain0.00002424Direct
MATH domain0.00003784Direct
Pleckstrin-homology domain (PH domain)0.00005041Direct
PH0987 C-terminal domain-like0.00009478Direct
MYND zinc finger0.0001272Direct
Family 6 carbohydrate binding module, CBM60.0001272Direct
E-set domains of sugar-utilizing enzymes0.0001989Direct
Transglutaminase core0.000293Direct
RibD C-terminal domain-like0.000387Direct
PaaI/YdiI-like0.000452Direct
PH0987 N-terminal domain-like0.000452Direct
4-alpha-glucanotransferase, N-terminal domain0.0005338Direct
Acyl-carrier protein (ACP)0.0005338Direct
DEK C-terminal domain0.0005338Direct
Third domain of FERM0.0005937Direct
Ricin B-like0.001482Inherited
BCR-homology GTPase activation domain (BH-domain)0.001734Inherited
Cell wall binding repeat0.001814Inherited
Anthrax toxin lethal factor, N- and C-terminal domains0.002157Inherited
GS domain0.002157Inherited
Galactose-binding domain0.002198Inherited
4-alpha-glucanotransferase, domain 20.002198Inherited
4-alpha-glucanotransferase, C-terminal domain0.002198Inherited
Ras GEF0.002198Inherited
DNase I-like0.002504Inherited
SAP domain0.003308Inherited
DNA repair glycosylase, 2 C-terminal domains0.003435Inherited
First domain of FERM0.003732Inherited
FAH0.005814Inherited
Probable phosphatase YrbI0.006006Inherited
DnaQ-like 3'-5' exonuclease0.007979Inherited
Hydroxynitrile lyase-like0.008846Inherited
F-box domain0.008846Inherited
MIT domain0.01276Inherited
Intein (protein splicing domain)0.02114Inherited
Chaperone J-domain0.02196Inherited
Glycosyltransferase family 36 C-terminal domain0.02428Inherited
Thioesterase domain of polypeptide, polyketide and fatty acid synthases0.0244Inherited
Leucine rich effector protein YopM0.02582Inherited
Second domain of FERM0.02625Inherited
PX domain0.0373Inherited
PHP domain0.05318Inherited
Haloperoxidase0.07077Inherited
UDP-N-acetylglucosamine 2-epimerase0.07393Inherited
MaoC-like0.07393Inherited
Canonical RBD0.09276Inherited
PDZ domain0.09331Inherited
Ran binding protein zinc finger-like0.09686Inherited
DNA repair glycosylase, N-terminal domain0.1063Inherited
FHA domain0.1073Inherited
PP1699/LP2961-like0.1241Inherited
mRNA capping enzyme0.1612Inherited
FYVE, a phosphatidylinositol-3-phosphate binding domain0.1672Inherited
RelA/SpoT domain0.2001Inherited
Scavenger receptor cysteine-rich (SRCR) domain0.2023Inherited
AlkB-like0.2277Inherited
CoA transferase alpha subunit-like0.2598Inherited
HMA, heavy metal-associated domain0.2679Inherited
PBP transglycosylase domain-like0.3213Inherited
Ecto-ART0.389Inherited
Ankyrin repeat0.4159Inherited
Pyruvate oxidase and decarboxylase, middle domain0.6525Inherited
I set domains0.777Inherited
Prokaryotic type I DNA topoisomerase0.8028Inherited
ABC transporter transmembrane region0.822Inherited
a tRNA synthase domain0.886Inherited
FabD-like0.9069Inherited
mRNA cap (Guanine N-7) methyltransferase0.9157Inherited
Ras-binding domain, RBD0.9315Inherited
Bromodomain0.9363Inherited
WD40-repeat0.9497Inherited
Growth factor receptor domain0.9542Inherited
GGDEF domain0.9649Inherited
5' to 3' exonuclease catalytic domain0.9785Inherited
BC N-terminal domain-like1Inherited
Metal cation-transporting ATPase, ATP-binding domain N1Inherited
Meta-cation ATPase, catalytic domain P1Inherited
Tetratricopeptide repeat (TPR)1Inherited
L-histidinol dehydrogenase HisD1Inherited
Pyruvate oxidase and decarboxylase PP module1Inherited
CCCH zinc finger1Inherited
Tryptophan synthase beta subunit-like PLP-dependent enzymes1Inherited
Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain1Inherited
Terpenoid cyclase N-terminal domain1Inherited
Alcohol dehydrogenase-like, C-terminal domain1Inherited
Nitrogenase iron protein-like1Inherited
ROK1Inherited
HpcH/HpaI aldolase1Inherited
Amidase signature (AS) enzymes1Inherited
PHD domain1Inherited
Probable ACP-binding domain of malonyl-CoA ACP transacylase1Inherited
Anticodon-binding domain of Class II aaRS1Inherited
Formyltransferase1Inherited
Thiolase-related1Inherited
Alcohol dehydrogenase-like, N-terminal domain1Inherited
Crotonase-like1Inherited
Class II glutamine amidotransferases1Inherited
Cystathionine synthase-like1Inherited
Terpenoid cyclase C-terminal domain1Inherited
Aspartate/ornithine carbamoyltransferase1Inherited
Glutathione peroxidase-like1Inherited
WW domain1Inherited
Cold shock DNA-binding domain-like1Inherited
Carbamoyl phosphate synthetase, large subunit connection domain1Inherited
BC ATP-binding domain-like1Inherited
Trehalose-6-phosphate synthase, OtsA1Inherited
RecA protein-like (ATPase-domain)1Inherited
Tyrosine-dependent oxidoreductases1Inherited
ABC transporter ATPase domain-like1Inherited
Pyruvate oxidase and decarboxylase Pyr module1Inherited
Calcium ATPase, transmembrane domain M1Inherited
SH3-domain1Inherited
LDH N-terminal domain-like1Inherited
SAM (sterile alpha motif) domain1Inherited
Imidazole glycerol phosphate dehydratase1Inherited
Nucleotide and nucleoside kinases1Inherited
Methylated DNA-protein cysteine methyltransferase, C-terminal domain1Inherited
Cofactor-dependent phosphoglycerate mutase1Inherited
Calcium ATPase, transduction domain A1Inherited
DNA polymerase I1Inherited
beta-carbonic anhydrase, cab1Inherited
Glucose 6-phosphate dehydrogenase-like1Inherited
SPRY domain1Inherited
Carbamoyl phosphate synthetase, small subunit N-terminal domain1Inherited
AraD-like aldolase/epimerase1Inherited
SH2 domain1Inherited
Phosphate binding protein-like1Inherited
Carbonic anhydrase1Inherited


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Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
AN1-like Zinc finger0Direct
Glutaminase/Asparaginase0Direct
Fumarylacetoacetate hydrolase, FAH, N-terminal domain0Direct
CheY-like0Direct
Families 57/38 glycoside transferase middle domain0Direct
Class I glutamine amidotransferase-like0Direct
Viral leader polypeptide zinc finger0Direct
SARS Nsp1-like0Direct
Tetrahydrobiopterin biosynthesis enzymes-like0Direct
SpoIIaa-like0Direct
Dcp2 domain-like0Direct
DNA/RNA polymerases0Direct
Dextranase, N-terminal domain0Direct
Subtilisin-like0Direct
Aminopeptidase/glucanase lid domain0Direct
JAB1/MPN domain0Direct
GroEL equatorial domain-like0Direct
DPP6 N-terminal domain-like0Direct
Viral glycoprotein, central and dimerisation domains0Direct
Hemopexin-like domain0Direct
AbfB domain0Direct
Influenza hemagglutinin (stalk)0Direct
Metallo-hydrolase/oxidoreductase0Direct
S13-like H2TH domain0Direct
Glucocorticoid receptor-like (DNA-binding domain)0Direct
HisI-like0Direct
X-Prolyl dipeptidyl aminopeptidase PepX, N-terminal domain0Direct
Protein serine/threonine phosphatase 2C, C-terminal domain0Direct
Retrovirus capsid protein, N-terminal core domain0Direct
N-terminal Zn binding domain of HIV integrase0Direct
GLA-domain0Direct
OMPT-like0Direct
Transthyretin (synonym: prealbumin)0Direct
Methylglyoxal synthase-like0Direct
Phospholipase A2, PLA20Direct
DTD-like0Direct
Restriction endonuclease-like0Direct
PGBD-like0Direct
Cytidine deaminase-like0Direct
XseB-like0Direct
Peptidylarginine deiminase Pad4, middle domain0Direct
Positive stranded ssRNA viruses0Direct
Metallo-dependent phosphatases0Direct
Chitinase insertion domain0Direct
Creatininase0Direct
Inorganic pyrophosphatase0Direct
dsRNA-binding domain-like0Direct
Calpain large subunit, middle domain (domain III)0Direct
Spermadhesin, CUB domain0Direct
ssDNA viruses0Direct
N-terminal nucleophile aminohydrolases (Ntn hydrolases)0Direct
Metalloproteases ("zincins"), catalytic domain0Direct
Cdc48 domain 2-like0Direct
SEA domain0Direct
Metallo-dependent hydrolases0Direct
Transferrin receptor-like dimerisation domain0Direct
N-terminal domain of DnaB helicase0Direct
Autotransporter0Direct
SurE-like0Direct
Invertebrate chitin-binding proteins0Direct
Voltage-gated potassium channels0Direct
CNF1/YfiH-like putative cysteine hydrolases0Direct
Acylphosphatase/BLUF domain-like0Direct
Carbon-nitrogen hydrolase0Direct
Macro domain-like0Direct
Soluble domain of poliovirus core protein 3a0Direct
Replicase NSP90Direct
EndoU-like0Direct
Oligoxyloglucan reducing end-specific cellobiohydrolase0Direct
Purple acid phosphatase, N-terminal domain0Direct
"Winged helix" DNA-binding domain0Direct
EF-G C-terminal domain-like0Direct
FabD/lysophospholipase-like0Direct
PKD domain0Direct
TSP-1 type 1 repeat0Direct
ComB-like0Direct
Ribonuclease H-like0Direct
HRDC-like0Direct
Beta-D-glucan exohydrolase, C-terminal domain0Direct
DUSP-like0Direct
CbiG N-terminal domain-like0Direct
Uracil-DNA glycosylase-like0Direct
C-terminal domain of PLC-beta0Direct
Leukotriene A4 hydrolase N-terminal domain0Direct
Bacterial exopeptidase dimerisation domain0Direct
LigT-like0Direct
beta-N-acetylhexosaminidase-like domain0Direct
Carbohydrate phosphatase0Direct
Aminoacid dehydrogenase-like, N-terminal domain0Direct
DNA primase core0Direct
alpha/beta-Hydrolases0Direct
C2 domain (Calcium/lipid-binding domain, CaLB)0Direct
Carbohydrate-binding domain0Direct
Pectin lyase-like0Direct
Type I dockerin domain0Direct
Coronavirus NSP8-like0Direct
Concanavalin A-like lectins/glucanases0Direct
L9 N-domain-like0Direct
5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain0Direct
Ribosome inactivating proteins (RIP)0Direct
Coronavirus NSP10-like0Direct
Nudix0Direct
NSP3A-like0Direct
Beta-galactosidase LacA, domain 30Direct
Trefoil0Direct
SGNH hydrolase0Direct
Carboxypeptidase regulatory domain-like0Direct
Sortase0Direct
CobE/GbiG C-terminal domain-like0Direct
Caspase-like0Direct
HybD-like0Direct
Prokaryotic SH3-related domain0Direct
RNase A-like0Direct
Pyrrolidone carboxyl peptidase (pyroglutamate aminopeptidase)0Direct
DNA-binding domain of retroviral integrase0Direct
R3H domain0Direct
Peptidyl-tRNA hydrolase-like0Direct
cAMP-binding domain-like0Direct
AlbA-like0Direct
Rnp2-like0Direct
Herpes virus serine proteinase, assemblin0Direct
Arginase/deacetylase0Direct
Putative isomerase YbhE0Direct
Hedgehog/DD-peptidase0Direct
Nitrous oxide reductase, N-terminal domain0Direct
Cellulose-binding domain0Direct
LmbE-like0Direct
BRK domain-like0Direct
C-terminal domain of Ku800Direct
Retrovirus zinc finger-like domains0Direct
His-Me finger endonucleases0Direct
Formate/glycerate dehydrogenase catalytic domain-like0Direct
Penicillin-binding protein associated domain0Direct
Seven-hairpin glycosidases0Direct
Composite domain of metallo-dependent hydrolases0Direct
Saposin0Direct
Penicillin binding protein dimerisation domain0Direct
DNase I-like0Direct
PDZ domain-like0Direct
Peptide deformylase0Direct
Urease, gamma-subunit0Direct
Microbial ribonucleases0Direct
Sec63 N-terminal domain-like0Direct
N-acetylmuramoyl-L-alanine amidase-like0Direct
Clostridium neurotoxins, "coiled-coil" domain0Direct
beta-Galactosidase/glucuronidase domain0Direct
(Phosphotyrosine protein) phosphatases II0Direct
Retrovirus capsid dimerization domain-like0Direct
Thermostable phytase (3-phytase)0Direct
(Trans)glycosidases0Direct
Peptidyl-tRNA hydrolase domain-like0Direct
Rap30/74 interaction domains0Direct
Zn-dependent exopeptidases0Direct
Heat shock protein 70kD (HSP70), C-terminal subdomain0Direct
Peptidyl-tRNA hydrolase II0Direct
Dipeptidyl peptidase I (cathepsin C), exclusion domain0Direct
Hyaluronidase post-catalytic domain-like0Direct
Collagen-binding domain0Direct
Peptidase/esterase 'gauge' domain0Direct
Kringle-like0Direct
Invasin/intimin cell-adhesion fragments0Direct
ClpP/crotonase0Direct
Heat shock protein 70kD (HSP70), peptide-binding domain0Direct
Phospholipase C/P1 nuclease0Direct
CinA-like0Direct
Rhomboid-like0Direct
Trypsin-like serine proteases0Direct
Somatomedin B domain0Direct
EGF/Laminin0Direct
ITPase-like0Direct
Cap-Gly domain0Direct
Retroviral matrix proteins0Direct
Viral protein domain0Direct
Cystatin/monellin0Direct
Plant invertase/pectin methylesterase inhibitor0Direct
Archaeal IMP cyclohydrolase PurO0Direct
HAD-like0Direct
all-alpha NTP pyrophosphatases0Direct
Arabinanase/levansucrase/invertase0Direct
P-loop containing nucleoside triphosphate hydrolases0Direct
CRAL/TRIO N-terminal domain0Direct
Six-hairpin glycosidases0Direct
TMV-like viral coat proteins0Direct
Methylesterase CheB, C-terminal domain0Direct
Acid phosphatase/Vanadium-dependent haloperoxidase0Direct
Isochorismatase-like hydrolases0Direct
Flavivirus capsid protein C0Direct
DNA helicase RuvA subunit, C-terminal domain0Direct
Phage fibre proteins0Direct
Pentein0Direct
mRNA decapping enzyme DcpS N-terminal domain0Direct
Origin of replication-binding domain, RBD-like0Direct
Anthrax protective antigen0Direct
Protease propeptides/inhibitors0Direct
beta-lactamase/transpeptidase-like0Direct
LD-carboxypeptidase A C-terminal domain-like0Direct
Sec-C motif0Direct
Glycosyl hydrolases family 6, cellulases0Direct
Initiation factor IF2/eIF5b, domain 30Direct
STI-like0Direct
Apyrase0Direct
Complement control module/SCR domain0Direct
Toprim domain0Direct
Sulfolobus fructose-1,6-bisphosphatase-like0Direct
Acetamidase/Formamidase-like0Direct
Holliday junction resolvase RusA0Direct
Glycoside hydrolase/deacetylase0Direct
RuvA domain 2-like0Direct
Bacterial GAP domain0Direct
PAZ domain0Direct
Galactose mutarotase-like0Direct
Ribonuclease Rh-like0Direct
RNase III domain-like0Direct
ADP-ribosylglycohydrolase0Direct
Rof/RNase P subunit-like0Direct
Glycosyl hydrolase domain0Direct
Outer membrane phospholipase A (OMPLA)0Direct
Sialidases0Direct
MCP/YpsA-like0Direct
Nucleoside hydrolase0Direct
AF0625-like0Direct
PP2C-like0Direct
Putative cyclase0Direct
D-aminopeptidase, middle and C-terminal domains0Direct
dUTPase-like0Direct
HIT-like0Direct
SPOC domain-like0Direct
Plant lectins/antimicrobial peptides0Direct
Blood coagulation inhibitor (disintegrin)0Direct
Acid proteases0Direct
Coronavirus NSP7-like0Direct
N-terminal domain of MutM-like DNA repair proteins0Direct
Urease, beta-subunit0Direct
Cellulose docking domain, dockering0Direct
Galactose-binding domain-like0Direct
RibA-like0Direct
CYTH-like phosphatases0Direct
Carbohydrate binding domain0Direct
Creatinase/aminopeptidase0Direct
Type X cellulose binding domain, CBDX0Direct
Creatinase/prolidase N-terminal domain0Direct
Methenyltetrahydromethanopterin cyclohydrolase0Direct
PLC-like phosphodiesterases0Direct
Cysteine proteinases0Direct
LexA/Signal peptidase0Direct
Kazal-type serine protease inhibitors0Direct
DHH phosphoesterases0Direct
Lysozyme-like0Direct
Xylose isomerase-like3.528e-16Direct
PH domain-like3.528e-16Direct
E set domains0.000000000000002099Direct
HD-domain/PDEase-like0.000000000000003488Direct
vWA-like0.000000000000005569Direct
Calcium-dependent phosphotriesterase0.00000000000001764Direct
LysM domain0.00000000000003541Direct
EF-hand0.0000000000000815Direct
Translation proteins0.00000000000046Direct
EAL domain-like0.0000000000005204Direct
Purine and uridine phosphorylases0.000000000001069Direct
Phosphotyrosine protein phosphatases I0.00000000004037Direct
Ribosomal protein S5 domain 2-like0.00000000008472Direct
Staphylococcal nuclease0.0000000007587Direct
PA domain0.0000000007903Direct
Ubiquitin-like0.000000001373Direct
UBA-like0.000000007306Direct
Hairpin loop containing domain-like0.00000001568Direct
GAF domain-like0.00000004857Direct
LDL receptor-like module0.00000007061Direct
YjgF-like0.00000009293Direct
Tudor/PWWP/MBT0.00000009501Direct
DEATH domain0.0000001143Direct
Phospholipase D/nuclease0.0000001267Direct
Lipase/lipooxygenase domain (PLAT/LH2 domain)0.0000005339Direct
Fibronectin type III0.0000005497Direct
Starch-binding domain-like0.00000129Direct
N-(deoxy)ribosyltransferase-like0.000001647Direct
NagB/RpiA/CoA transferase-like0.000004203Direct
beta-Roll0.000004872Direct
PUG domain-like0.000006227Direct
Phosphoglycerate mutase-like0.000008751Direct
DNA clamp0.00001819Direct
CBD9-like0.00001819Direct
HCP-like0.00002354Direct
DEK C-terminal domain0.00002709Direct
PH0987 N-terminal domain-like0.00008794Direct
HIT/MYND zinc finger-like0.00008845Direct
FnI-like domain0.000232Direct
Hedgehog/intein (Hint) domain0.000308Direct
Barwin-like endoglucanases0.0003237Direct
GroEL-intermediate domain like0.0004255Direct
Ricin B-like lectins0.0004772Direct
Chromo domain-like0.0005842Direct
SRCR-like0.0008526Direct
GTPase activation domain, GAP0.001617Inherited
Cell wall binding repeat0.001668Inherited
Ras GEF0.002071Inherited
WD40 repeat-like0.002235Inherited
SAP domain0.002968Inherited
Integrin alpha N-terminal domain0.003963Inherited
FAH0.006387Inherited
PX domain0.007388Inherited
F-box domain0.008397Inherited
GroEL apical domain-like0.01403Inherited
Rhodanese/Cell cycle control phosphatase0.01563Inherited
RNA-binding domain, RBD0.01624Inherited
Chaperone J-domain0.02087Inherited
MIT domain0.02232Inherited
DNA-glycosylase0.02532Inherited
Second domain of FERM0.02998Inherited
Homing endonucleases0.03156Inherited
Duplicated hybrid motif0.03284Inherited
C-terminal (heme d1) domain of cytochrome cd1-nitrite reductase0.04052Inherited
PHP domain-like0.05419Inherited
SMAD/FHA domain0.08441Inherited
Ran binding protein zinc finger-like0.09068Inherited
TATA-box binding protein-like0.1019Inherited
HSP20-like chaperones0.1305Inherited
YrdC/RibB0.1329Inherited
CRAL/TRIO domain0.1424Inherited
TRAF domain-like0.247Inherited
HMA, heavy metal-associated domain0.247Inherited
NTF2-like0.2575Inherited
Ankyrin repeat0.415Inherited
Non-globular alpha+beta subunits of globular proteins0.5559Inherited
post-AAA+ oligomerization domain-like0.6018Inherited
ABC transporter transmembrane region0.7025Inherited
Prokaryotic type I DNA topoisomerase0.7694Inherited
PUA domain-like0.8181Inherited
Heme oxygenase-like0.8356Inherited
S15/NS1 RNA-binding domain0.8627Inherited
Kelch motif0.896Inherited
Bromodomain0.9126Inherited
L30e-like0.9428Inherited
Growth factor receptor domain0.9495Inherited
ARM repeat0.9512Inherited
PIN domain-like0.9571Inherited
beta-carbonic anhydrase, cab0.9699Inherited
LuxS/MPP-like metallohydrolase0.9798Inherited
Quinoprotein alcohol dehydrogenase-like0.986Inherited
FYVE/PHD zinc finger0.9905Inherited
Alkaline phosphatase-like1Inherited
WW domain1Inherited
SH3-domain1Inherited
SH2 domain1Inherited
Tryptophan synthase beta subunit-like PLP-dependent enzymes1Inherited
Actin-like ATPase domain1Inherited
Carbamoyl phosphate synthetase, large subunit connection domain1Inherited
SAM/Pointed domain1Inherited
Carbonic anhydrase1Inherited
Clavaminate synthase-like1Inherited
Periplasmic binding protein-like II1Inherited
ACP-like1Inherited
S-adenosyl-L-methionine-dependent methyltransferases1Inherited
Aspartate/ornithine carbamoyltransferase1Inherited
Thiamin diphosphate-binding fold (THDP-binding)1Inherited
ACT-like1Inherited
UDP-Glycosyltransferase/glycogen phosphorylase1Inherited
L domain-like1Inherited
PLP-dependent transferases1Inherited
Carbamoyl phosphate synthetase, small subunit N-terminal domain1Inherited
Acyl-CoA N-acyltransferases (Nat)1Inherited
Terpenoid cyclases/Protein prenyltransferases1Inherited
CCCH zinc finger1Inherited
Dihydrofolate reductase-like1Inherited
ADC-like1Inherited
Thiolase-like1Inherited
PYP-like sensor domain (PAS domain)1Inherited
Formyltransferase1Inherited
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase1Inherited
Methylated DNA-protein cysteine methyltransferase, C-terminal domain1Inherited
Nucleotidyltransferase1Inherited
Calcium ATPase, transduction domain A1Inherited
Cyclophilin-like1Inherited
DHS-like NAD/FAD-binding domain1Inherited
PreATP-grasp domain1Inherited
Inosine monophosphate dehydrogenase (IMPDH)1Inherited
Terpenoid synthases1Inherited
Bet v1-like1Inherited
GroES-like1Inherited
NAD(P)-binding Rossmann-fold domains1Inherited
FMT C-terminal domain-like1Inherited
Cupredoxins1Inherited
Metal cation-transporting ATPase, ATP-binding domain N1Inherited
Immunoglobulin1Inherited
Probable ACP-binding domain of malonyl-CoA ACP transacylase1Inherited
RmlC-like cupins1Inherited
PHP14-like1Inherited
AraD/HMP-PK domain-like1Inherited
TGS-like1Inherited
DNA ligase/mRNA capping enzyme, catalytic domain1Inherited
Thioesterase/thiol ester dehydrase-isomerase1Inherited
Amidase signature (AS) enzymes1Inherited
Calcium ATPase, transmembrane domain M1Inherited
Phosphoenolpyruvate/pyruvate domain1Inherited
Thioredoxin-like1Inherited
LDH C-terminal domain-like1Inherited
Nucleic acid-binding proteins1Inherited
ADP-ribosylation1Inherited
Nucleotide cyclase1Inherited
RING/U-box1Inherited
Class II aaRS ABD-related1Inherited
TPR-like1Inherited

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
50494,56672
  • 50494 - Trypsin-like serine proteases
  • 56672 - DNA/RNA polymerases
  • 0Direct
    54585,52540
  • 54585 - Cdc48 domain 2-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    57440,50494
  • 57440 - Kringle-like
  • 50494 - Trypsin-like serine proteases
  • 0Direct
    50692,54585
  • 50692 - ADC-like
  • 54585 - Cdc48 domain 2-like
  • 0Direct
    51445,49785
  • 51445 - (Trans)glycosidases
  • 49785 - Galactose-binding domain-like
  • 0Direct
    81324,52799
  • 81324 - Voltage-gated potassium channels
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 0Direct
    53300,100939
  • 53300 - vWA-like
  • 100939 - SPOC domain-like
  • 0Direct
    57630,57184
  • 57630 - GLA-domain
  • 57184 - Growth factor receptor domain
  • 0Direct
    51206,51206
  • 51206 - cAMP-binding domain-like
  • 51206 - cAMP-binding domain-like
  • 0Direct
    160481,160481
  • 160481 - BRK domain-like
  • 160481 - BRK domain-like
  • 0Direct
    82708,53098
  • 82708 - R3H domain
  • 53098 - Ribonuclease H-like
  • 0Direct
    51445,51055
  • 51445 - (Trans)glycosidases
  • 51055 - Carbohydrate binding domain
  • 0Direct
    50249,56300
  • 50249 - Nucleic acid-binding proteins
  • 56300 - Metallo-dependent phosphatases
  • 0Direct
    63737,55486
  • 63737 - Leukotriene A4 hydrolase N-terminal domain
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 0Direct
    54001,88633
  • 54001 - Cysteine proteinases
  • 88633 - Positive stranded ssRNA viruses
  • 0Direct
    51445,64571
  • 51445 - (Trans)glycosidases
  • 64571 - Cellulose docking domain, dockering
  • 0Direct
    52743,52025
  • 52743 - Subtilisin-like
  • 52025 - PA domain
  • 0Direct
    53187,47672
  • 53187 - Zn-dependent exopeptidases
  • 47672 - Transferrin receptor-like dimerisation domain
  • 0Direct
    49363,56300
  • 49363 - Purple acid phosphatase, N-terminal domain
  • 56300 - Metallo-dependent phosphatases
  • 0Direct
    52540,54980
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 54980 - EF-G C-terminal domain-like
  • 0Direct
    52058,56219
  • 52058 - L domain-like
  • 56219 - DNase I-like
  • 0Direct
    52129,81296
  • 52129 - Caspase-like
  • 81296 - E set domains
  • 0Direct
    53098,51283
  • 53098 - Ribonuclease H-like
  • 51283 - dUTPase-like
  • 0Direct
    54160,54160
  • 54160 - Chromo domain-like
  • 54160 - Chromo domain-like
  • 0Direct
    50729,47473
  • 50729 - PH domain-like
  • 47473 - EF-hand
  • 0Direct
    47473,144091
  • 47473 - EF-hand
  • 144091 - Rhomboid-like
  • 0Direct
    47090,55486
  • 47090 - PGBD-like
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 0Direct
    57756,51283
  • 57756 - Retrovirus zinc finger-like domains
  • 51283 - dUTPase-like
  • 0Direct
    57196,50494
  • 57196 - EGF/Laminin
  • 50494 - Trypsin-like serine proteases
  • 0Direct
    48150,55811
  • 48150 - DNA-glycosylase
  • 55811 - Nudix
  • 0Direct
    57603,57440
  • 57603 - FnI-like domain
  • 57440 - Kringle-like
  • 0Direct
    48024,52540
  • 48024 - N-terminal domain of DnaB helicase
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    48592,54849
  • 48592 - GroEL equatorial domain-like
  • 54849 - GroEL-intermediate domain like
  • 0Direct
    53067,100920
  • 53067 - Actin-like ATPase domain
  • 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
  • 0Direct
    51011,49265
  • 51011 - Glycosyl hydrolase domain
  • 49265 - Fibronectin type III
  • 0Direct
    51283,51283
  • 51283 - dUTPase-like
  • 51283 - dUTPase-like
  • 0Direct
    50249,50249
  • 50249 - Nucleic acid-binding proteins
  • 50249 - Nucleic acid-binding proteins
  • 0Direct
    51445,49384
  • 51445 - (Trans)glycosidases
  • 49384 - Carbohydrate-binding domain
  • 0Direct
    51069,49265
  • 51069 - Carbonic anhydrase
  • 49265 - Fibronectin type III
  • 0Direct
    50494,50156
  • 50494 - Trypsin-like serine proteases
  • 50156 - PDZ domain-like
  • 0Direct
    49854,49899
  • 49854 - Spermadhesin, CUB domain
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0Direct
    55486,48371
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 48371 - ARM repeat
  • 0Direct
    51445,54556
  • 51445 - (Trans)glycosidases
  • 54556 - Chitinase insertion domain
  • 0Direct
    158702,81296
  • 158702 - Sec63 N-terminal domain-like
  • 81296 - E set domains
  • 0Direct
    49464,53187
  • 49464 - Carboxypeptidase regulatory domain-like
  • 53187 - Zn-dependent exopeptidases
  • 0Direct
    49303,74650
  • 49303 - beta-Galactosidase/glucuronidase domain
  • 74650 - Galactose mutarotase-like
  • 0Direct
    56672,53098
  • 56672 - DNA/RNA polymerases
  • 53098 - Ribonuclease H-like
  • 0Direct
    49854,57196
  • 49854 - Spermadhesin, CUB domain
  • 57196 - EGF/Laminin
  • 0Direct
    47836,47943
  • 47836 - Retroviral matrix proteins
  • 47943 - Retrovirus capsid protein, N-terminal core domain
  • 0Direct
    49899,49854
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49854 - Spermadhesin, CUB domain
  • 0Direct
    52540,49899
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0Direct
    52949,53187
  • 52949 - Macro domain-like
  • 53187 - Zn-dependent exopeptidases
  • 0Direct
    55658,53098
  • 55658 - L9 N-domain-like
  • 53098 - Ribonuclease H-like
  • 0Direct
    89043,50494
  • 89043 - Soluble domain of poliovirus core protein 3a
  • 50494 - Trypsin-like serine proteases
  • 0Direct
    49854,57424
  • 49854 - Spermadhesin, CUB domain
  • 57424 - LDL receptor-like module
  • 0Direct
    54160,52540
  • 54160 - Chromo domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    53474,49723
  • 53474 - alpha/beta-Hydrolases
  • 49723 - Lipase/lipooxygenase domain (PLAT/LH2 domain)
  • 0Direct
    81624,46946
  • 81624 - N-terminal domain of MutM-like DNA repair proteins
  • 46946 - S13-like H2TH domain
  • 0Direct
    81606,81601
  • 81606 - PP2C-like
  • 81601 - Protein serine/threonine phosphatase 2C, C-terminal domain
  • 0Direct
    46785,158702
  • 46785 - "Winged helix" DNA-binding domain
  • 158702 - Sec63 N-terminal domain-like
  • 0Direct
    53649,54060
  • 53649 - Alkaline phosphatase-like
  • 54060 - His-Me finger endonucleases
  • 0Direct
    57196,49854
  • 57196 - EGF/Laminin
  • 49854 - Spermadhesin, CUB domain
  • 0Direct
    52283,51735
  • 52283 - Formate/glycerate dehydrogenase catalytic domain-like
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 0Direct
    52799,56091
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 56091 - DNA ligase/mRNA capping enzyme, catalytic domain
  • 0Direct
    53098,53098
  • 53098 - Ribonuclease H-like
  • 53098 - Ribonuclease H-like
  • 0Direct
    55846,47090
  • 55846 - N-acetylmuramoyl-L-alanine amidase-like
  • 47090 - PGBD-like
  • 0Direct
    52540,57756
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 57756 - Retrovirus zinc finger-like domains
  • 0Direct
    47943,47353
  • 47943 - Retrovirus capsid protein, N-terminal core domain
  • 47353 - Retrovirus capsid dimerization domain-like
  • 0Direct
    49303,51445
  • 49303 - beta-Galactosidase/glucuronidase domain
  • 51445 - (Trans)glycosidases
  • 0Direct
    55486,57440
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 57440 - Kringle-like
  • 0Direct
    57630,57440
  • 57630 - GLA-domain
  • 57440 - Kringle-like
  • 0Direct
    50447,54980
  • 50447 - Translation proteins
  • 54980 - EF-G C-terminal domain-like
  • 0Direct
    49899,50386
  • 49899 - Concanavalin A-like lectins/glucanases
  • 50386 - STI-like
  • 0Direct
    49785,49303
  • 49785 - Galactose-binding domain-like
  • 49303 - beta-Galactosidase/glucuronidase domain
  • 0Direct
    49599,54001
  • 49599 - TRAF domain-like
  • 54001 - Cysteine proteinases
  • 0Direct
    49785,63446
  • 49785 - Galactose-binding domain-like
  • 63446 - Type I dockerin domain
  • 0Direct
    55781,55781
  • 55781 - GAF domain-like
  • 55781 - GAF domain-like
  • 0Direct
    56300,55816
  • 56300 - Metallo-dependent phosphatases
  • 55816 - 5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain
  • 0Direct
    54001,49785
  • 54001 - Cysteine proteinases
  • 49785 - Galactose-binding domain-like
  • 0Direct
    51283,46919
  • 51283 - dUTPase-like
  • 46919 - N-terminal Zn binding domain of HIV integrase
  • 0Direct
    52540,52540
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    52499,47336
  • 52499 - Isochorismatase-like hydrolases
  • 47336 - ACP-like
  • 0Direct
    56219,56219
  • 56219 - DNase I-like
  • 56219 - DNase I-like
  • 0Direct
    54236,54001
  • 54236 - Ubiquitin-like
  • 54001 - Cysteine proteinases
  • 0Direct
    57414,57440
  • 57414 - Hairpin loop containing domain-like
  • 57440 - Kringle-like
  • 0Direct
    56487,50494
  • 56487 - SRCR-like
  • 50494 - Trypsin-like serine proteases
  • 0Direct
    53187,49464
  • 53187 - Zn-dependent exopeptidases
  • 49464 - Carboxypeptidase regulatory domain-like
  • 0Direct
    49384,57615
  • 49384 - Carbohydrate-binding domain
  • 57615 - Type X cellulose binding domain, CBDX
  • 0Direct
    53474,53474
  • 53474 - alpha/beta-Hydrolases
  • 53474 - alpha/beta-Hydrolases
  • 0Direct
    53092,53092
  • 53092 - Creatinase/prolidase N-terminal domain
  • 53092 - Creatinase/prolidase N-terminal domain
  • 0Direct
    53300,50494
  • 53300 - vWA-like
  • 50494 - Trypsin-like serine proteases
  • 0Direct
    49562,56024
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 56024 - Phospholipase D/nuclease
  • 0Direct
    52540,142877
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 142877 - EndoU-like
  • 0Direct
    52540,54928
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 54928 - RNA-binding domain, RBD
  • 0Direct
    56371,50370
  • 56371 - Ribosome inactivating proteins (RIP)
  • 50370 - Ricin B-like lectins
  • 0Direct
    101908,56219
  • 101908 - Putative isomerase YbhE
  • 56219 - DNase I-like
  • 0Direct
    51283,50630
  • 51283 - dUTPase-like
  • 50630 - Acid proteases
  • 0Direct
    50156,52799
  • 50156 - PDZ domain-like
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 0Direct
    57535,57535
  • 57535 - Complement control module/SCR domain
  • 57535 - Complement control module/SCR domain
  • 0Direct
    74650,51445
  • 74650 - Galactose mutarotase-like
  • 51445 - (Trans)glycosidases
  • 0Direct
    47781,46929
  • 47781 - RuvA domain 2-like
  • 46929 - DNA helicase RuvA subunit, C-terminal domain
  • 0Direct
    54111,51278
  • 54111 - Urease, gamma-subunit
  • 51278 - Urease, beta-subunit
  • 0Direct
    51445,140657
  • 51445 - (Trans)glycosidases
  • 140657 - Hyaluronidase post-catalytic domain-like
  • 0Direct
    51011,51445
  • 51011 - Glycosyl hydrolase domain
  • 51445 - (Trans)glycosidases
  • 0Direct
    55486,82895
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 82895 - TSP-1 type 1 repeat
  • 0Direct
    143503,54001
  • 143503 - PUG domain-like
  • 54001 - Cysteine proteinases
  • 0Direct
    54001,46934
  • 54001 - Cysteine proteinases
  • 46934 - UBA-like
  • 0Direct
    55464,52540
  • 55464 - Origin of replication-binding domain, RBD-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    90188,90188
  • 90188 - Somatomedin B domain
  • 90188 - Somatomedin B domain
  • 0Direct
    51445,51011
  • 51445 - (Trans)glycosidases
  • 51011 - Glycosyl hydrolase domain
  • 0Direct
    56784,54211
  • 56784 - HAD-like
  • 54211 - Ribosomal protein S5 domain 2-like
  • 0Direct
    141734,101386
  • 141734 - HisI-like
  • 101386 - all-alpha NTP pyrophosphatases
  • 0Direct
    56983,81296
  • 56983 - Viral glycoprotein, central and dimerisation domains
  • 81296 - E set domains
  • 0Direct
    101821,53187
  • 101821 - Aminopeptidase/glucanase lid domain
  • 53187 - Zn-dependent exopeptidases
  • 0Direct
    56601,52091
  • 56601 - beta-lactamase/transpeptidase-like
  • 52091 - SpoIIaa-like
  • 0Direct
    101386,53720
  • 101386 - all-alpha NTP pyrophosphatases
  • 53720 - ALDH-like
  • 0Direct
    56784,54427
  • 56784 - HAD-like
  • 54427 - NTF2-like
  • 0Direct
    53335,142877
  • 53335 - S-adenosyl-L-methionine-dependent methyltransferases
  • 142877 - EndoU-like
  • 0Direct
    50156,52096
  • 50156 - PDZ domain-like
  • 52096 - ClpP/crotonase
  • 0Direct
    53098,47819
  • 53098 - Ribonuclease H-like
  • 47819 - HRDC-like
  • 0Direct
    52799,52799
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 0Direct
    57180,51445
  • 57180 - Cellulose-binding domain
  • 51445 - (Trans)glycosidases
  • 0Direct
    100895,56487
  • 100895 - Kazal-type serine protease inhibitors
  • 56487 - SRCR-like
  • 0Direct
    89260,89260
  • 89260 - Collagen-binding domain
  • 89260 - Collagen-binding domain
  • 0Direct
    53335,56672
  • 53335 - S-adenosyl-L-methionine-dependent methyltransferases
  • 56672 - DNA/RNA polymerases
  • 0Direct
    75001,54001
  • 75001 - Dipeptidyl peptidase I (cathepsin C), exclusion domain
  • 54001 - Cysteine proteinases
  • 0Direct
    49562,52151
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 52151 - FabD/lysophospholipase-like
  • 0Direct
    50729,56024
  • 50729 - PH domain-like
  • 56024 - Phospholipase D/nuclease
  • 0Direct
    -9,52540
  • -9 - PDB
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    81761,53474
  • 81761 - X-Prolyl dipeptidyl aminopeptidase PepX, N-terminal domain
  • 53474 - alpha/beta-Hydrolases
  • 0Direct
    54001,143791
  • 54001 - Cysteine proteinases
  • 143791 - DUSP-like
  • 0Direct
    159936,52949
  • 159936 - NSP3A-like
  • 52949 - Macro domain-like
  • 0Direct
    54001,55205
  • 54001 - Cysteine proteinases
  • 55205 - EPT/RTPC-like
  • 0Direct
    52743,49785
  • 52743 - Subtilisin-like
  • 49785 - Galactose-binding domain-like
  • 0Direct
    53955,54106
  • 53955 - Lysozyme-like
  • 54106 - LysM domain
  • 0Direct
    49854,57535
  • 49854 - Spermadhesin, CUB domain
  • 57535 - Complement control module/SCR domain
  • 0Direct
    47473,51695
  • 47473 - EF-hand
  • 51695 - PLC-like phosphodiesterases
  • 0Direct
    49899,48726
  • 49899 - Concanavalin A-like lectins/glucanases
  • 48726 - Immunoglobulin
  • 0Direct
    81296,48208
  • 81296 - E set domains
  • 48208 - Six-hairpin glycosidases
  • 0Direct
    52540,89043
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 89043 - Soluble domain of poliovirus core protein 3a
  • 0Direct
    49503,110083
  • 49503 - Cupredoxins
  • 110083 - Peptidylarginine deiminase Pad4, middle domain
  • 0Direct
    49899,57180
  • 49899 - Concanavalin A-like lectins/glucanases
  • 57180 - Cellulose-binding domain
  • 0Direct
    49879,54197
  • 49879 - SMAD/FHA domain
  • 54197 - HIT-like
  • 0Direct
    88633,50494
  • 88633 - Positive stranded ssRNA viruses
  • 50494 - Trypsin-like serine proteases
  • 0Direct
    51445,52317
  • 51445 - (Trans)glycosidases
  • 52317 - Class I glutamine amidotransferase-like
  • 0Direct
    48371,54001
  • 48371 - ARM repeat
  • 54001 - Cysteine proteinases
  • 0Direct
    55550,52799
  • 55550 - SH2 domain
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 0Direct
    54897,53187
  • 54897 - Protease propeptides/inhibitors
  • 53187 - Zn-dependent exopeptidases
  • 0Direct
    54001,53098
  • 54001 - Cysteine proteinases
  • 53098 - Ribonuclease H-like
  • 0Direct
    55608,56712
  • 55608 - Homing endonucleases
  • 56712 - Prokaryotic type I DNA topoisomerase
  • 0Direct
    57535,50494
  • 57535 - Complement control module/SCR domain
  • 50494 - Trypsin-like serine proteases
  • 0Direct
    82895,82895
  • 82895 - TSP-1 type 1 repeat
  • 82895 - TSP-1 type 1 repeat
  • 0Direct
    52980,47781
  • 52980 - Restriction endonuclease-like
  • 47781 - RuvA domain 2-like
  • 0Direct
    50199,63748
  • 50199 - Staphylococcal nuclease
  • 63748 - Tudor/PWWP/MBT
  • 0Direct
    74924,54001
  • 74924 - Cap-Gly domain
  • 54001 - Cysteine proteinases
  • 0Direct
    48208,49384
  • 48208 - Six-hairpin glycosidases
  • 49384 - Carbohydrate-binding domain
  • 0Direct
    57424,56487
  • 57424 - LDL receptor-like module
  • 56487 - SRCR-like
  • 0Direct
    69065,54768
  • 69065 - RNase III domain-like
  • 54768 - dsRNA-binding domain-like
  • 0Direct
    52151,51412
  • 52151 - FabD/lysophospholipase-like
  • 51412 - Inosine monophosphate dehydrogenase (IMPDH)
  • 0Direct
    53098,46919
  • 53098 - Ribonuclease H-like
  • 46919 - N-terminal Zn binding domain of HIV integrase
  • 0Direct
    52540,47819
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 47819 - HRDC-like
  • 0Direct
    100939,68906
  • 100939 - SPOC domain-like
  • 68906 - SAP domain
  • 0Direct
    52768,52768
  • 52768 - Arginase/deacetylase
  • 52768 - Arginase/deacetylase
  • 0Direct
    53067,109604
  • 53067 - Actin-like ATPase domain
  • 109604 - HD-domain/PDEase-like
  • 0Direct
    47233,52799
  • 47233 - Bacterial GAP domain
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 0Direct
    55781,109604
  • 55781 - GAF domain-like
  • 109604 - HD-domain/PDEase-like
  • 0Direct
    55154,56091
  • 55154 - CYTH-like phosphatases
  • 56091 - DNA ligase/mRNA capping enzyme, catalytic domain
  • 0Direct
    48208,63446
  • 48208 - Six-hairpin glycosidases
  • 63446 - Type I dockerin domain
  • 0Direct
    56784,56784
  • 56784 - HAD-like
  • 56784 - HAD-like
  • 0Direct
    56672,52540
  • 56672 - DNA/RNA polymerases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    53335,52949
  • 53335 - S-adenosyl-L-methionine-dependent methyltransferases
  • 52949 - Macro domain-like
  • 0Direct
    52540,-9
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • -9 - PDB
  • 0Direct
    143791,143791
  • 143791 - DUSP-like
  • 143791 - DUSP-like
  • 0Direct
    57016,53955
  • 57016 - Plant lectins/antimicrobial peptides
  • 53955 - Lysozyme-like
  • 0Direct
    101816,144246
  • 101816 - Replicase NSP9
  • 144246 - Coronavirus NSP10-like
  • 0Direct
    52540,47370
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 47370 - Bromodomain
  • 0Direct
    54236,56784
  • 54236 - Ubiquitin-like
  • 56784 - HAD-like
  • 0Direct
    50044,51695
  • 50044 - SH3-domain
  • 51695 - PLC-like phosphodiesterases
  • 0Direct
    56731,52540
  • 56731 - DNA primase core
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    51338,51556
  • 51338 - Composite domain of metallo-dependent hydrolases
  • 51556 - Metallo-dependent hydrolases
  • 0Direct
    52540,-8
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • -8 - ECOD
  • 0Direct
    49899,49599
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49599 - TRAF domain-like
  • 0Direct
    90188,53649
  • 90188 - Somatomedin B domain
  • 53649 - Alkaline phosphatase-like
  • 0Direct
    101386,101386
  • 101386 - all-alpha NTP pyrophosphatases
  • 101386 - all-alpha NTP pyrophosphatases
  • 0Direct
    49384,51445
  • 49384 - Carbohydrate-binding domain
  • 51445 - (Trans)glycosidases
  • 0Direct
    51695,49562
  • 51695 - PLC-like phosphodiesterases
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 0Direct
    49452,52799
  • 49452 - Starch-binding domain-like
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 0Direct
    54637,52151
  • 54637 - Thioesterase/thiol ester dehydrase-isomerase
  • 52151 - FabD/lysophospholipase-like
  • 0Direct
    48537,49723
  • 48537 - Phospholipase C/P1 nuclease
  • 49723 - Lipase/lipooxygenase domain (PLAT/LH2 domain)
  • 0Direct
    158702,52540
  • 158702 - Sec63 N-terminal domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    56487,57424
  • 56487 - SRCR-like
  • 57424 - LDL receptor-like module
  • 0Direct
    46785,51306
  • 46785 - "Winged helix" DNA-binding domain
  • 51306 - LexA/Signal peptidase
  • 0Direct
    101148,51126
  • 101148 - Plant invertase/pectin methylesterase inhibitor
  • 51126 - Pectin lyase-like
  • 0Direct
    55486,51120
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 51120 - beta-Roll
  • 0Direct
    69065,69065
  • 69065 - RNase III domain-like
  • 69065 - RNase III domain-like
  • 0Direct
    64571,64571
  • 64571 - Cellulose docking domain, dockering
  • 64571 - Cellulose docking domain, dockering
  • 0Direct
    49265,49384
  • 49265 - Fibronectin type III
  • 49384 - Carbohydrate-binding domain
  • 0Direct
    56784,52540
  • 56784 - HAD-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    50916,46785
  • 50916 - Rap30/74 interaction domains
  • 46785 - "Winged helix" DNA-binding domain
  • 0Direct
    52317,141986
  • 52317 - Class I glutamine amidotransferase-like
  • 141986 - LD-carboxypeptidase A C-terminal domain-like
  • 0Direct
    50993,53474
  • 50993 - Peptidase/esterase 'gauge' domain
  • 53474 - alpha/beta-Hydrolases
  • 0Direct
    52317,51011
  • 52317 - Class I glutamine amidotransferase-like
  • 51011 - Glycosyl hydrolase domain
  • 0Direct
    50630,56672
  • 50630 - Acid proteases
  • 56672 - DNA/RNA polymerases
  • 0Direct
    49785,49785
  • 49785 - Galactose-binding domain-like
  • 49785 - Galactose-binding domain-like
  • 0Direct
    51011,50370
  • 51011 - Glycosyl hydrolase domain
  • 50370 - Ricin B-like lectins
  • 0Direct
    140586,55811
  • 140586 - Dcp2 domain-like
  • 55811 - Nudix
  • 0Direct
    56300,56300
  • 56300 - Metallo-dependent phosphatases
  • 56300 - Metallo-dependent phosphatases
  • 0Direct
    56601,48403
  • 56601 - beta-lactamase/transpeptidase-like
  • 48403 - Ankyrin repeat
  • 0Direct
    -8,52540
  • -8 - ECOD
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    49854,50494
  • 49854 - Spermadhesin, CUB domain
  • 50494 - Trypsin-like serine proteases
  • 0Direct
    88713,88688
  • 88713 - Glycoside hydrolase/deacetylase
  • 88688 - Families 57/38 glycoside transferase middle domain
  • 0Direct
    53927,53927
  • 53927 - Cytidine deaminase-like
  • 53927 - Cytidine deaminase-like
  • 0Direct
    46946,57716
  • 46946 - S13-like H2TH domain
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 0Direct
    50370,50370
  • 50370 - Ricin B-like lectins
  • 50370 - Ricin B-like lectins
  • 0Direct
    48452,56300
  • 48452 - TPR-like
  • 56300 - Metallo-dependent phosphatases
  • 0Direct
    47986,47986
  • 47986 - DEATH domain
  • 47986 - DEATH domain
  • 0Direct
    55486,49899
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0Direct
    52540,48403
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 48403 - Ankyrin repeat
  • 0Direct
    52172,52738
  • 52172 - CheY-like
  • 52738 - Methylesterase CheB, C-terminal domain
  • 0Direct
    55550,50044
  • 55550 - SH2 domain
  • 50044 - SH3-domain
  • 0Direct
    100920,100934
  • 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
  • 100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain
  • 0Direct
    57184,50494
  • 57184 - Growth factor receptor domain
  • 50494 - Trypsin-like serine proteases
  • 0Direct
    57630,57196
  • 57630 - GLA-domain
  • 57196 - EGF/Laminin
  • 0Direct
    100939,101420
  • 100939 - SPOC domain-like
  • 101420 - C-terminal domain of Ku80
  • 0Direct
    50249,47781
  • 50249 - Nucleic acid-binding proteins
  • 47781 - RuvA domain 2-like
  • 0Direct
    57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0Direct
    75005,49899
  • 75005 - Arabinanase/levansucrase/invertase
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0Direct
    117100,49785
  • 117100 - Beta-galactosidase LacA, domain 3
  • 49785 - Galactose-binding domain-like
  • 0Direct
    57424,50494
  • 57424 - LDL receptor-like module
  • 50494 - Trypsin-like serine proteases
  • 0Direct
    52266,49818
  • 52266 - SGNH hydrolase
  • 49818 - Viral protein domain
  • 0Direct
    48403,52151
  • 48403 - Ankyrin repeat
  • 52151 - FabD/lysophospholipase-like
  • 0Direct
    52266,103515
  • 52266 - SGNH hydrolase
  • 103515 - Autotransporter
  • 0Direct
    46919,53098
  • 46919 - N-terminal Zn binding domain of HIV integrase
  • 53098 - Ribonuclease H-like
  • 0Direct
    52156,50447
  • 52156 - Initiation factor IF2/eIF5b, domain 3
  • 50447 - Translation proteins
  • 0Direct
    52151,52151
  • 52151 - FabD/lysophospholipase-like
  • 52151 - FabD/lysophospholipase-like
  • 0Direct
    143791,54236
  • 143791 - DUSP-like
  • 54236 - Ubiquitin-like
  • 0Direct
    47986,52129
  • 47986 - DEATH domain
  • 52129 - Caspase-like
  • 0Direct
    49384,49265
  • 49384 - Carbohydrate-binding domain
  • 49265 - Fibronectin type III
  • 0Direct
    52821,52799
  • 52821 - Rhodanese/Cell cycle control phosphatase
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 0Direct
    74924,74924
  • 74924 - Cap-Gly domain
  • 74924 - Cap-Gly domain
  • 0Direct
    47819,47819
  • 47819 - HRDC-like
  • 47819 - HRDC-like
  • 0Direct
    56300,47473
  • 56300 - Metallo-dependent phosphatases
  • 47473 - EF-hand
  • 0Direct
    54897,52743
  • 54897 - Protease propeptides/inhibitors
  • 52743 - Subtilisin-like
  • 0Direct
    82671,49854
  • 82671 - SEA domain
  • 49854 - Spermadhesin, CUB domain
  • 0Direct
    51556,51338
  • 51556 - Metallo-dependent hydrolases
  • 51338 - Composite domain of metallo-dependent hydrolases
  • 0Direct
    56519,56601
  • 56519 - Penicillin binding protein dimerisation domain
  • 56601 - beta-lactamase/transpeptidase-like
  • 0Direct
    52540,46785
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 46785 - "Winged helix" DNA-binding domain
  • 0Direct
    82171,53474
  • 82171 - DPP6 N-terminal domain-like
  • 53474 - alpha/beta-Hydrolases
  • 0Direct
    63433,56529
  • 63433 - Fumarylacetoacetate hydrolase, FAH, N-terminal domain
  • 56529 - FAH
  • 0Direct
    54403,54001
  • 54403 - Cystatin/monellin
  • 54001 - Cysteine proteinases
  • 0Direct
    57424,49854
  • 57424 - LDL receptor-like module
  • 49854 - Spermadhesin, CUB domain
  • 0Direct
    46785,47819
  • 46785 - "Winged helix" DNA-binding domain
  • 47819 - HRDC-like
  • 0Direct
    110296,110296
  • 110296 - Oligoxyloglucan reducing end-specific cellobiohydrolase
  • 110296 - Oligoxyloglucan reducing end-specific cellobiohydrolase
  • 0Direct
    53187,55031
  • 53187 - Zn-dependent exopeptidases
  • 55031 - Bacterial exopeptidase dimerisation domain
  • 0Direct
    55920,46785
  • 55920 - Creatinase/aminopeptidase
  • 46785 - "Winged helix" DNA-binding domain
  • 0Direct
    102860,54197
  • 102860 - mRNA decapping enzyme DcpS N-terminal domain
  • 54197 - HIT-like
  • 0Direct
    53474,49785
  • 53474 - alpha/beta-Hydrolases
  • 49785 - Galactose-binding domain-like
  • 0Direct
    88633,88633
  • 88633 - Positive stranded ssRNA viruses
  • 88633 - Positive stranded ssRNA viruses
  • 0Direct
    110083,55909
  • 110083 - Peptidylarginine deiminase Pad4, middle domain
  • 55909 - Pentein
  • 0Direct
    49344,49344
  • 49344 - CBD9-like
  • 49344 - CBD9-like
  • 0Direct
    52540,54211
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 54211 - Ribosomal protein S5 domain 2-like
  • 0Direct
    53098,54928
  • 53098 - Ribonuclease H-like
  • 54928 - RNA-binding domain, RBD
  • 0Direct
    140367,143076
  • 140367 - Coronavirus NSP7-like
  • 143076 - Coronavirus NSP8-like
  • 0Direct
    159936,53335
  • 159936 - NSP3A-like
  • 53335 - S-adenosyl-L-methionine-dependent methyltransferases
  • 0Direct
    51445,52279
  • 51445 - (Trans)glycosidases
  • 52279 - Beta-D-glucan exohydrolase, C-terminal domain
  • 0Direct
    54001,144232
  • 54001 - Cysteine proteinases
  • 144232 - HIT/MYND zinc finger-like
  • 0Direct
    50729,52799
  • 50729 - PH domain-like
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 0Direct
    49899,110221
  • 49899 - Concanavalin A-like lectins/glucanases
  • 110221 - AbfB domain
  • 0Direct
    52540,55144
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 55144 - LigT-like
  • 0Direct
    51445,49344
  • 51445 - (Trans)glycosidases
  • 49344 - CBD9-like
  • 0Direct
    57440,57440
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 0Direct
    54211,54637
  • 54211 - Ribosomal protein S5 domain 2-like
  • 54637 - Thioesterase/thiol ester dehydrase-isomerase
  • 0Direct
    53223,51735
  • 53223 - Aminoacid dehydrogenase-like, N-terminal domain
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 0Direct
    49899,52540
  • 49899 - Concanavalin A-like lectins/glucanases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    101596,51126
  • 101596 - Dextranase, N-terminal domain
  • 51126 - Pectin lyase-like
  • 0Direct
    51445,49303
  • 51445 - (Trans)glycosidases
  • 49303 - beta-Galactosidase/glucuronidase domain
  • 0Direct
    48208,49452
  • 48208 - Six-hairpin glycosidases
  • 49452 - Starch-binding domain-like
  • 0Direct
    55545,51445
  • 55545 - beta-N-acetylhexosaminidase-like domain
  • 51445 - (Trans)glycosidases
  • 0Direct
    56784,53474
  • 56784 - HAD-like
  • 53474 - alpha/beta-Hydrolases
  • 0Direct
    55021,53328
  • 55021 - ACT-like
  • 53328 - Formyltransferase
  • 0Direct
    57850,54001
  • 57850 - RING/U-box
  • 54001 - Cysteine proteinases
  • 0Direct
    51126,51126
  • 51126 - Pectin lyase-like
  • 51126 - Pectin lyase-like
  • 0Direct
    101690,53098
  • 101690 - PAZ domain
  • 53098 - Ribonuclease H-like
  • 0Direct
    57535,53300
  • 57535 - Complement control module/SCR domain
  • 53300 - vWA-like
  • 0Direct
    57424,57424
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 0Direct
    49899,49384
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49384 - Carbohydrate-binding domain
  • 0Direct
    47090,47090
  • 47090 - PGBD-like
  • 47090 - PGBD-like
  • 0Direct
    116846,52540
  • 116846 - MIT domain
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    51445,63446
  • 51445 - (Trans)glycosidases
  • 63446 - Type I dockerin domain
  • 0Direct
    51445,57180
  • 51445 - (Trans)glycosidases
  • 57180 - Cellulose-binding domain
  • 0Direct
    50974,50974
  • 50974 - Nitrous oxide reductase, N-terminal domain
  • 50974 - Nitrous oxide reductase, N-terminal domain
  • 0Direct
    103642,55920
  • 103642 - Sec-C motif
  • 55920 - Creatinase/aminopeptidase
  • 0Direct
    49562,54236
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 54236 - Ubiquitin-like
  • 0Direct
    56568,47233
  • 56568 - Non-globular alpha+beta subunits of globular proteins
  • 47233 - Bacterial GAP domain
  • 0Direct
    47353,57756
  • 47353 - Retrovirus capsid dimerization domain-like
  • 57756 - Retrovirus zinc finger-like domains
  • 0Direct
    54637,55961
  • 54637 - Thioesterase/thiol ester dehydrase-isomerase
  • 55961 - Bet v1-like
  • 0Direct
    49265,49452
  • 49265 - Fibronectin type III
  • 49452 - Starch-binding domain-like
  • 0Direct
    55486,57552
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 57552 - Blood coagulation inhibitor (disintegrin)
  • 0Direct
    49785,51445
  • 49785 - Galactose-binding domain-like
  • 51445 - (Trans)glycosidases
  • 0Direct
    56672,46919
  • 56672 - DNA/RNA polymerases
  • 46919 - N-terminal Zn binding domain of HIV integrase
  • 0Direct
    52025,53187
  • 52025 - PA domain
  • 53187 - Zn-dependent exopeptidases
  • 0Direct
    50886,50886
  • 50886 - D-aminopeptidase, middle and C-terminal domains
  • 50886 - D-aminopeptidase, middle and C-terminal domains
  • 0Direct
    63411,63411
  • 63411 - LuxS/MPP-like metallohydrolase
  • 63411 - LuxS/MPP-like metallohydrolase
  • 0Direct
    50494,52540
  • 50494 - Trypsin-like serine proteases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    52540,56672
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 56672 - DNA/RNA polymerases
  • 0Direct
    52540,56712
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 56712 - Prokaryotic type I DNA topoisomerase
  • 0Direct
    49854,49854
  • 49854 - Spermadhesin, CUB domain
  • 49854 - Spermadhesin, CUB domain
  • 0Direct
    82671,57424
  • 82671 - SEA domain
  • 57424 - LDL receptor-like module
  • 0Direct
    53092,55920
  • 53092 - Creatinase/prolidase N-terminal domain
  • 55920 - Creatinase/aminopeptidase
  • 0Direct
    52540,50447
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 50447 - Translation proteins
  • 0Direct
    54106,54001
  • 54106 - LysM domain
  • 54001 - Cysteine proteinases
  • 0Direct
    55811,55811
  • 55811 - Nudix
  • 55811 - Nudix
  • 0Direct
    49265,51445
  • 49265 - Fibronectin type III
  • 51445 - (Trans)glycosidases
  • 0Direct
    50249,52540
  • 50249 - Nucleic acid-binding proteins
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    57440,57196
  • 57440 - Kringle-like
  • 57196 - EGF/Laminin
  • 0Direct
    49303,49303
  • 49303 - beta-Galactosidase/glucuronidase domain
  • 49303 - beta-Galactosidase/glucuronidase domain
  • 0Direct
    51011,117100
  • 51011 - Glycosyl hydrolase domain
  • 117100 - Beta-galactosidase LacA, domain 3
  • 0Direct
    46938,52087
  • 46938 - CRAL/TRIO N-terminal domain
  • 52087 - CRAL/TRIO domain
  • 0Direct
    143076,101816
  • 143076 - Coronavirus NSP8-like
  • 101816 - Replicase NSP9
  • 0Direct
    49899,49785
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49785 - Galactose-binding domain-like
  • 0Direct
    53639,56784
  • 53639 - AraD/HMP-PK domain-like
  • 56784 - HAD-like
  • 0Direct
    56219,54928
  • 56219 - DNase I-like
  • 54928 - RNA-binding domain, RBD
  • 0Direct
    50199,50199
  • 50199 - Staphylococcal nuclease
  • 50199 - Staphylococcal nuclease
  • 0Direct
    49299,89260
  • 49299 - PKD domain
  • 89260 - Collagen-binding domain
  • 0Direct
    52335,53927
  • 52335 - Methylglyoxal synthase-like
  • 53927 - Cytidine deaminase-like
  • 0Direct
    55821,142695
  • 55821 - YrdC/RibB
  • 142695 - RibA-like
  • 0Direct
    52279,56988
  • 52279 - Beta-D-glucan exohydrolase, C-terminal domain
  • 56988 - Anthrax protective antigen
  • 0Direct
    55486,50923
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 50923 - Hemopexin-like domain
  • 0Direct
    54001,49758
  • 54001 - Cysteine proteinases
  • 49758 - Calpain large subunit, middle domain (domain III)
  • 0Direct
    159672,159664
  • 159672 - CbiG N-terminal domain-like
  • 159664 - CobE/GbiG C-terminal domain-like
  • 0Direct
    57756,50630
  • 57756 - Retrovirus zinc finger-like domains
  • 50630 - Acid proteases
  • 0Direct
    58091,49899
  • 58091 - Clostridium neurotoxins, "coiled-coil" domain
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0Direct
    51695,51695
  • 51695 - PLC-like phosphodiesterases
  • 51695 - PLC-like phosphodiesterases
  • 0Direct
    54980,54980
  • 54980 - EF-G C-terminal domain-like
  • 54980 - EF-G C-terminal domain-like
  • 0Direct
    54211,54211
  • 54211 - Ribosomal protein S5 domain 2-like
  • 54211 - Ribosomal protein S5 domain 2-like
  • 0Direct
    53756,53067
  • 53756 - UDP-Glycosyltransferase/glycogen phosphorylase
  • 53067 - Actin-like ATPase domain
  • 0Direct
    51445,81296
  • 51445 - (Trans)glycosidases
  • 81296 - E set domains
  • 0Direct
    53774,48403
  • 53774 - Glutaminase/Asparaginase
  • 48403 - Ankyrin repeat
  • 0Direct
    49384,55545
  • 49384 - Carbohydrate-binding domain
  • 55545 - beta-N-acetylhexosaminidase-like domain
  • 0Direct
    56601,69189
  • 56601 - beta-lactamase/transpeptidase-like
  • 69189 - Penicillin-binding protein associated domain
  • 0Direct
    52540,52156
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52156 - Initiation factor IF2/eIF5b, domain 3
  • 0Direct
    55486,58091
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 58091 - Clostridium neurotoxins, "coiled-coil" domain
  • 0Direct
    109715,52799
  • 109715 - DEK C-terminal domain
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 0Direct
    56672,88633
  • 56672 - DNA/RNA polymerases
  • 88633 - Positive stranded ssRNA viruses
  • 0Direct
    51278,51338
  • 51278 - Urease, beta-subunit
  • 51338 - Composite domain of metallo-dependent hydrolases
  • 0Direct
    140657,49785
  • 140657 - Hyaluronidase post-catalytic domain-like
  • 49785 - Galactose-binding domain-like
  • 0Direct
    52087,52799
  • 52087 - CRAL/TRIO domain
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 0Direct
    57492,74650
  • 57492 - Trefoil
  • 74650 - Galactose mutarotase-like
  • 0Direct
    53098,50122
  • 53098 - Ribonuclease H-like
  • 50122 - DNA-binding domain of retroviral integrase
  • 0Direct
    49758,47473
  • 49758 - Calpain large subunit, middle domain (domain III)
  • 47473 - EF-hand
  • 0Direct
    56601,50886
  • 56601 - beta-lactamase/transpeptidase-like
  • 50886 - D-aminopeptidase, middle and C-terminal domains
  • 0Direct
    52540,53254
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 53254 - Phosphoglycerate mutase-like
  • 3.528e-16Direct
    50156,50156
  • 50156 - PDZ domain-like
  • 50156 - PDZ domain-like
  • 7.035e-16Direct
    49265,49265
  • 49265 - Fibronectin type III
  • 49265 - Fibronectin type III
  • 0.0000000000001181Direct
    54106,54106
  • 54106 - LysM domain
  • 54106 - LysM domain
  • 0.000000000002539Direct
    88688,74650
  • 88688 - Families 57/38 glycoside transferase middle domain
  • 74650 - Galactose mutarotase-like
  • 0.00000000003613Direct
    51735,52283
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 52283 - Formate/glycerate dehydrogenase catalytic domain-like
  • 0.00000000006002Direct
    53955,56601
  • 53955 - Lysozyme-like
  • 56601 - beta-lactamase/transpeptidase-like
  • 0.00000000006002Direct
    53927,53597
  • 53927 - Cytidine deaminase-like
  • 53597 - Dihydrofolate reductase-like
  • 0.000000000166Direct
    57756,57756
  • 57756 - Retrovirus zinc finger-like domains
  • 57756 - Retrovirus zinc finger-like domains
  • 0.00000001568Direct
    55550,55550
  • 55550 - SH2 domain
  • 55550 - SH2 domain
  • 0.0000000178Direct
    51445,51445
  • 51445 - (Trans)glycosidases
  • 51445 - (Trans)glycosidases
  • 0.00000003322Direct
    52799,49562
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 0.0000000935Direct
    64268,50729
  • 64268 - PX domain
  • 50729 - PH domain-like
  • 0.0000007797Direct
    54637,54637
  • 54637 - Thioesterase/thiol ester dehydrase-isomerase
  • 54637 - Thioesterase/thiol ester dehydrase-isomerase
  • 0.00001371Direct
    51011,49452
  • 51011 - Glycosyl hydrolase domain
  • 49452 - Starch-binding domain-like
  • 0.00001819Direct
    55073,141868
  • 55073 - Nucleotide cyclase
  • 141868 - EAL domain-like
  • 0.00001819Direct
    51197,52540
  • 51197 - Clavaminate synthase-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.00002709Direct
    48403,52540
  • 48403 - Ankyrin repeat
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.0000274Direct
    52540,51294
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 51294 - Hedgehog/intein (Hint) domain
  • 0.00003343Direct
    160467,50891
  • 160467 - PH0987 N-terminal domain-like
  • 50891 - Cyclophilin-like
  • 0.00008794Direct
    52335,51556
  • 52335 - Methylglyoxal synthase-like
  • 51556 - Metallo-dependent hydrolases
  • 0.0001092Direct
    63748,50199
  • 63748 - Tudor/PWWP/MBT
  • 50199 - Staphylococcal nuclease
  • 0.0001169Direct
    48726,49265
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 0.0001215Direct
    49899,50939
  • 49899 - Concanavalin A-like lectins/glucanases
  • 50939 - Sialidases
  • 0.0004239Direct
    54849,52029
  • 54849 - GroEL-intermediate domain like
  • 52029 - GroEL apical domain-like
  • 0.0004255Direct
    54236,47031
  • 54236 - Ubiquitin-like
  • 47031 - Second domain of FERM
  • 0.0005272Direct
    54768,54768
  • 54768 - dsRNA-binding domain-like
  • 54768 - dsRNA-binding domain-like
  • 0.001617Inherited
    56712,51294
  • 56712 - Prokaryotic type I DNA topoisomerase
  • 51294 - Hedgehog/intein (Hint) domain
  • 0.002047Inherited
    90209,90209
  • 90209 - Ran binding protein zinc finger-like
  • 90209 - Ran binding protein zinc finger-like
  • 0.002047Inherited
    49785,81296
  • 49785 - Galactose-binding domain-like
  • 81296 - E set domains
  • 0.002071Inherited
    52317,52440
  • 52317 - Class I glutamine amidotransferase-like
  • 52440 - PreATP-grasp domain
  • 0.00317Inherited
    47031,50729
  • 47031 - Second domain of FERM
  • 50729 - PH domain-like
  • 0.005948Inherited
    47336,53474
  • 47336 - ACP-like
  • 53474 - alpha/beta-Hydrolases
  • 0.008124Inherited
    51294,55608
  • 51294 - Hedgehog/intein (Hint) domain
  • 55608 - Homing endonucleases
  • 0.01293Inherited
    53474,53335
  • 53474 - alpha/beta-Hydrolases
  • 53335 - S-adenosyl-L-methionine-dependent methyltransferases
  • 0.02087Inherited
    100950,100950
  • 100950 - NagB/RpiA/CoA transferase-like
  • 100950 - NagB/RpiA/CoA transferase-like
  • 0.03284Inherited
    81296,51445
  • 81296 - E set domains
  • 51445 - (Trans)glycosidases
  • 0.04226Inherited
    81301,81271
  • 81301 - Nucleotidyltransferase
  • 81271 - TGS-like
  • 0.06171Inherited
    55608,52540
  • 55608 - Homing endonucleases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.06766Inherited
    55945,48150
  • 55945 - TATA-box binding protein-like
  • 48150 - DNA-glycosylase
  • 0.1019Inherited
    54236,54236
  • 54236 - Ubiquitin-like
  • 54236 - Ubiquitin-like
  • 0.1424Inherited
    109604,81301
  • 109604 - HD-domain/PDEase-like
  • 81301 - Nucleotidyltransferase
  • 0.1449Inherited
    74650,48208
  • 74650 - Galactose mutarotase-like
  • 48208 - Six-hairpin glycosidases
  • 0.2675Inherited
    49899,49899
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.2894Inherited
    53756,56784
  • 53756 - UDP-Glycosyltransferase/glycogen phosphorylase
  • 56784 - HAD-like
  • 0.3083Inherited
    52317,51366
  • 52317 - Class I glutamine amidotransferase-like
  • 51366 - Ribulose-phoshate binding barrel
  • 0.325Inherited
    56024,56024
  • 56024 - Phospholipase D/nuclease
  • 56024 - Phospholipase D/nuclease
  • 0.3943Inherited
    47060,55681
  • 47060 - S15/NS1 RNA-binding domain
  • 55681 - Class II aaRS and biotin synthetases
  • 0.3982Inherited
    52540,48019
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 48019 - post-AAA+ oligomerization domain-like
  • 0.6018Inherited
    49785,57184
  • 49785 - Galactose-binding domain-like
  • 57184 - Growth factor receptor domain
  • 0.6378Inherited
    90123,52540
  • 90123 - ABC transporter transmembrane region
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.689Inherited
    52058,52058
  • 52058 - L domain-like
  • 52058 - L domain-like
  • 0.7543Inherited
    51735,51735
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 0.8116Inherited
    51735,47336
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 47336 - ACP-like
  • 0.8249Inherited
    48108,52440
  • 48108 - Carbamoyl phosphate synthetase, large subunit connection domain
  • 52440 - PreATP-grasp domain
  • 1Inherited
    50129,51735
  • 50129 - GroES-like
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 1Inherited
    51735,56327
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 56327 - LDH C-terminal domain-like
  • 1Inherited
    81660,56784
  • 81660 - Metal cation-transporting ATPase, ATP-binding domain N
  • 56784 - HAD-like
  • 1Inherited
    52151,55048
  • 52151 - FabD/lysophospholipase-like
  • 55048 - Probable ACP-binding domain of malonyl-CoA ACP transacylase
  • 1Inherited
    52021,52317
  • 52021 - Carbamoyl phosphate synthetase, small subunit N-terminal domain
  • 52317 - Class I glutamine amidotransferase-like
  • 1Inherited
    56091,50249
  • 56091 - DNA ligase/mRNA capping enzyme, catalytic domain
  • 50249 - Nucleic acid-binding proteins
  • 1Inherited
    53098,56672
  • 53098 - Ribonuclease H-like
  • 56672 - DNA/RNA polymerases
  • 1Inherited
    52467,52518
  • 52467 - DHS-like NAD/FAD-binding domain
  • 52518 - Thiamin diphosphate-binding fold (THDP-binding)
  • 1Inherited
    56784,81665
  • 56784 - HAD-like
  • 81665 - Calcium ATPase, transmembrane domain M
  • 1Inherited
    52518,52467
  • 52518 - Thiamin diphosphate-binding fold (THDP-binding)
  • 52467 - DHS-like NAD/FAD-binding domain
  • 1Inherited
    48726,48726
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 1Inherited
    53067,53067
  • 53067 - Actin-like ATPase domain
  • 53067 - Actin-like ATPase domain
  • 1Inherited
    52440,56059
  • 52440 - PreATP-grasp domain
  • 56059 - Glutathione synthetase ATP-binding domain-like
  • 1Inherited
    48239,48576
  • 48239 - Terpenoid cyclases/Protein prenyltransferases
  • 48576 - Terpenoid synthases
  • 1Inherited
    56059,48108
  • 56059 - Glutathione synthetase ATP-binding domain-like
  • 48108 - Carbamoyl phosphate synthetase, large subunit connection domain
  • 1Inherited
    56059,52335
  • 56059 - Glutathione synthetase ATP-binding domain-like
  • 52335 - Methylglyoxal synthase-like
  • 1Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    50044,51695,49562
  • 50044 - SH3-domain
  • 51695 - PLC-like phosphodiesterases
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 0Direct
    55486,57440,57440
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 0Direct
    57414,57440,57440
  • 57414 - Hairpin loop containing domain-like
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 0Direct
    57630,57196,50494
  • 57630 - GLA-domain
  • 57196 - EGF/Laminin
  • 50494 - Trypsin-like serine proteases
  • 0Direct
    49384,55545,51445
  • 49384 - Carbohydrate-binding domain
  • 55545 - beta-N-acetylhexosaminidase-like domain
  • 51445 - (Trans)glycosidases
  • 0Direct
    54111,51278,51338
  • 54111 - Urease, gamma-subunit
  • 51278 - Urease, beta-subunit
  • 51338 - Composite domain of metallo-dependent hydrolases
  • 0Direct
    50494,56672,88633
  • 50494 - Trypsin-like serine proteases
  • 56672 - DNA/RNA polymerases
  • 88633 - Positive stranded ssRNA viruses
  • 0Direct
    81324,52799,49562
  • 81324 - Voltage-gated potassium channels
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 0Direct
    52540,46785,47819
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 46785 - "Winged helix" DNA-binding domain
  • 47819 - HRDC-like
  • 0Direct
    55550,50044,51695
  • 55550 - SH2 domain
  • 50044 - SH3-domain
  • 51695 - PLC-like phosphodiesterases
  • 0Direct
    49785,49785,49785
  • 49785 - Galactose-binding domain-like
  • 49785 - Galactose-binding domain-like
  • 49785 - Galactose-binding domain-like
  • 0Direct
    57630,57196,57196
  • 57630 - GLA-domain
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0Direct
    82708,53098,54928
  • 82708 - R3H domain
  • 53098 - Ribonuclease H-like
  • 54928 - RNA-binding domain, RBD
  • 0Direct
    51011,117100,49785
  • 51011 - Glycosyl hydrolase domain
  • 117100 - Beta-galactosidase LacA, domain 3
  • 49785 - Galactose-binding domain-like
  • 0Direct
    49503,110083,55909
  • 49503 - Cupredoxins
  • 110083 - Peptidylarginine deiminase Pad4, middle domain
  • 55909 - Pentein
  • 0Direct
    51445,49785,63446
  • 51445 - (Trans)glycosidases
  • 49785 - Galactose-binding domain-like
  • 63446 - Type I dockerin domain
  • 0Direct
    57196,57196,50494
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 50494 - Trypsin-like serine proteases
  • 0Direct
    49899,48726,49265
  • 49899 - Concanavalin A-like lectins/glucanases
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 0Direct
    49854,49899,49854
  • 49854 - Spermadhesin, CUB domain
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49854 - Spermadhesin, CUB domain
  • 0Direct
    140367,143076,101816
  • 140367 - Coronavirus NSP7-like
  • 143076 - Coronavirus NSP8-like
  • 101816 - Replicase NSP9
  • 0Direct
    49785,49303,51445
  • 49785 - Galactose-binding domain-like
  • 49303 - beta-Galactosidase/glucuronidase domain
  • 51445 - (Trans)glycosidases
  • 0Direct
    57535,57535,50494
  • 57535 - Complement control module/SCR domain
  • 57535 - Complement control module/SCR domain
  • 50494 - Trypsin-like serine proteases
  • 0Direct
    54001,143791,143791
  • 54001 - Cysteine proteinases
  • 143791 - DUSP-like
  • 143791 - DUSP-like
  • 0Direct
    54211,54211,54637
  • 54211 - Ribosomal protein S5 domain 2-like
  • 54211 - Ribosomal protein S5 domain 2-like
  • 54637 - Thioesterase/thiol ester dehydrase-isomerase
  • 0Direct
    57756,51283,50630
  • 57756 - Retrovirus zinc finger-like domains
  • 51283 - dUTPase-like
  • 50630 - Acid proteases
  • 0Direct
    51283,50630,56672
  • 51283 - dUTPase-like
  • 50630 - Acid proteases
  • 56672 - DNA/RNA polymerases
  • 0Direct
    52540,52540,142877
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 142877 - EndoU-like
  • 0Direct
    48024,52540,51294
  • 48024 - N-terminal domain of DnaB helicase
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 51294 - Hedgehog/intein (Hint) domain
  • 0Direct
    50494,50156,50156
  • 50494 - Trypsin-like serine proteases
  • 50156 - PDZ domain-like
  • 50156 - PDZ domain-like
  • 0Direct
    57424,56487,50494
  • 57424 - LDL receptor-like module
  • 56487 - SRCR-like
  • 50494 - Trypsin-like serine proteases
  • 0Direct
    49303,51445,49303
  • 49303 - beta-Galactosidase/glucuronidase domain
  • 51445 - (Trans)glycosidases
  • 49303 - beta-Galactosidase/glucuronidase domain
  • 0Direct
    47353,57756,57756
  • 47353 - Retrovirus capsid dimerization domain-like
  • 57756 - Retrovirus zinc finger-like domains
  • 57756 - Retrovirus zinc finger-like domains
  • 0Direct
    51278,51338,51556
  • 51278 - Urease, beta-subunit
  • 51338 - Composite domain of metallo-dependent hydrolases
  • 51556 - Metallo-dependent hydrolases
  • 0Direct
    53098,51283,46919
  • 53098 - Ribonuclease H-like
  • 51283 - dUTPase-like
  • 46919 - N-terminal Zn binding domain of HIV integrase
  • 0Direct
    56672,53098,50122
  • 56672 - DNA/RNA polymerases
  • 53098 - Ribonuclease H-like
  • 50122 - DNA-binding domain of retroviral integrase
  • 0Direct
    51197,52540,52540
  • 51197 - Clavaminate synthase-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    56024,56024,56024
  • 56024 - Phospholipase D/nuclease
  • 56024 - Phospholipase D/nuclease
  • 56024 - Phospholipase D/nuclease
  • 0Direct
    52540,52156,50447
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52156 - Initiation factor IF2/eIF5b, domain 3
  • 50447 - Translation proteins
  • 0Direct
    46938,52087,52799
  • 46938 - CRAL/TRIO N-terminal domain
  • 52087 - CRAL/TRIO domain
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 0Direct
    46785,158702,81296
  • 46785 - "Winged helix" DNA-binding domain
  • 158702 - Sec63 N-terminal domain-like
  • 81296 - E set domains
  • 0Direct
    55550,55550,52799
  • 55550 - SH2 domain
  • 55550 - SH2 domain
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 0Direct
    50729,47473,51695
  • 50729 - PH domain-like
  • 47473 - EF-hand
  • 51695 - PLC-like phosphodiesterases
  • 0Direct
    57535,57535,57535
  • 57535 - Complement control module/SCR domain
  • 57535 - Complement control module/SCR domain
  • 57535 - Complement control module/SCR domain
  • 0Direct
    52540,46785,158702
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 46785 - "Winged helix" DNA-binding domain
  • 158702 - Sec63 N-terminal domain-like
  • 0Direct
    47986,47986,52129
  • 47986 - DEATH domain
  • 47986 - DEATH domain
  • 52129 - Caspase-like
  • 0Direct
    52540,89043,50494
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 89043 - Soluble domain of poliovirus core protein 3a
  • 50494 - Trypsin-like serine proteases
  • 0Direct
    81624,46946,57716
  • 81624 - N-terminal domain of MutM-like DNA repair proteins
  • 46946 - S13-like H2TH domain
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 0Direct
    51283,46919,53098
  • 51283 - dUTPase-like
  • 46919 - N-terminal Zn binding domain of HIV integrase
  • 53098 - Ribonuclease H-like
  • 0Direct
    47473,51695,49562
  • 47473 - EF-hand
  • 51695 - PLC-like phosphodiesterases
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 0Direct
    63737,55486,48371
  • 63737 - Leukotriene A4 hydrolase N-terminal domain
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 48371 - ARM repeat
  • 0Direct
    49265,49265,49265
  • 49265 - Fibronectin type III
  • 49265 - Fibronectin type III
  • 49265 - Fibronectin type III
  • 0Direct
    52540,52540,46785
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 46785 - "Winged helix" DNA-binding domain
  • 0Direct
    141734,101386,53720
  • 141734 - HisI-like
  • 101386 - all-alpha NTP pyrophosphatases
  • 53720 - ALDH-like
  • 0Direct
    50494,52540,89043
  • 50494 - Trypsin-like serine proteases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 89043 - Soluble domain of poliovirus core protein 3a
  • 0Direct
    49785,51445,64571
  • 49785 - Galactose-binding domain-like
  • 51445 - (Trans)glycosidases
  • 64571 - Cellulose docking domain, dockering
  • 0Direct
    54001,88633,88633
  • 54001 - Cysteine proteinases
  • 88633 - Positive stranded ssRNA viruses
  • 88633 - Positive stranded ssRNA viruses
  • 0Direct
    47090,55486,50923
  • 47090 - PGBD-like
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 50923 - Hemopexin-like domain
  • 0Direct
    57440,57440,50494
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 50494 - Trypsin-like serine proteases
  • 0Direct
    53098,47819,47819
  • 53098 - Ribonuclease H-like
  • 47819 - HRDC-like
  • 47819 - HRDC-like
  • 0Direct
    57535,57535,53300
  • 57535 - Complement control module/SCR domain
  • 57535 - Complement control module/SCR domain
  • 53300 - vWA-like
  • 0Direct
    54106,54106,54001
  • 54106 - LysM domain
  • 54106 - LysM domain
  • 54001 - Cysteine proteinases
  • 0Direct
    49854,57196,49854
  • 49854 - Spermadhesin, CUB domain
  • 57196 - EGF/Laminin
  • 49854 - Spermadhesin, CUB domain
  • 0Direct
    117100,49785,49785
  • 117100 - Beta-galactosidase LacA, domain 3
  • 49785 - Galactose-binding domain-like
  • 49785 - Galactose-binding domain-like
  • 0Direct
    57424,57424,57424
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 0Direct
    53067,53067,100920
  • 53067 - Actin-like ATPase domain
  • 53067 - Actin-like ATPase domain
  • 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
  • 0Direct
    55545,51445,140657
  • 55545 - beta-N-acetylhexosaminidase-like domain
  • 51445 - (Trans)glycosidases
  • 140657 - Hyaluronidase post-catalytic domain-like
  • 0Direct
    64268,50729,56024
  • 64268 - PX domain
  • 50729 - PH domain-like
  • 56024 - Phospholipase D/nuclease
  • 0Direct
    51445,51011,50370
  • 51445 - (Trans)glycosidases
  • 51011 - Glycosyl hydrolase domain
  • 50370 - Ricin B-like lectins
  • 0Direct
    52540,50447,54980
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 50447 - Translation proteins
  • 54980 - EF-G C-terminal domain-like
  • 0Direct
    54897,52743,49785
  • 54897 - Protease propeptides/inhibitors
  • 52743 - Subtilisin-like
  • 49785 - Galactose-binding domain-like
  • 0Direct
    74650,51445,51011
  • 74650 - Galactose mutarotase-like
  • 51445 - (Trans)glycosidases
  • 51011 - Glycosyl hydrolase domain
  • 0Direct
    52743,49785,57184
  • 52743 - Subtilisin-like
  • 49785 - Galactose-binding domain-like
  • 57184 - Growth factor receptor domain
  • 0Direct
    50199,50199,63748
  • 50199 - Staphylococcal nuclease
  • 50199 - Staphylococcal nuclease
  • 63748 - Tudor/PWWP/MBT
  • 0Direct
    50249,52540,52540
  • 50249 - Nucleic acid-binding proteins
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    51445,49303,74650
  • 51445 - (Trans)glycosidases
  • 49303 - beta-Galactosidase/glucuronidase domain
  • 74650 - Galactose mutarotase-like
  • 0Direct
    57196,49854,57535
  • 57196 - EGF/Laminin
  • 49854 - Spermadhesin, CUB domain
  • 57535 - Complement control module/SCR domain
  • 0Direct
    49854,57424,56487
  • 49854 - Spermadhesin, CUB domain
  • 57424 - LDL receptor-like module
  • 56487 - SRCR-like
  • 0Direct
    53067,100920,100934
  • 53067 - Actin-like ATPase domain
  • 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
  • 100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain
  • 0Direct
    56672,46919,53098
  • 56672 - DNA/RNA polymerases
  • 46919 - N-terminal Zn binding domain of HIV integrase
  • 53098 - Ribonuclease H-like
  • 0Direct
    50494,52540,52540
  • 50494 - Trypsin-like serine proteases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    47353,57756,50630
  • 47353 - Retrovirus capsid dimerization domain-like
  • 57756 - Retrovirus zinc finger-like domains
  • 50630 - Acid proteases
  • 0Direct
    81296,48208,63446
  • 81296 - E set domains
  • 48208 - Six-hairpin glycosidases
  • 63446 - Type I dockerin domain
  • 0Direct
    52540,52540,56712
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 56712 - Prokaryotic type I DNA topoisomerase
  • 0Direct
    51445,49785,49785
  • 51445 - (Trans)glycosidases
  • 49785 - Galactose-binding domain-like
  • 49785 - Galactose-binding domain-like
  • 0Direct
    53300,100939,68906
  • 53300 - vWA-like
  • 100939 - SPOC domain-like
  • 68906 - SAP domain
  • 0Direct
    56601,50886,50886
  • 56601 - beta-lactamase/transpeptidase-like
  • 50886 - D-aminopeptidase, middle and C-terminal domains
  • 50886 - D-aminopeptidase, middle and C-terminal domains
  • 0Direct
    56784,54211,54211
  • 56784 - HAD-like
  • 54211 - Ribosomal protein S5 domain 2-like
  • 54211 - Ribosomal protein S5 domain 2-like
  • 0Direct
    49785,49785,51445
  • 49785 - Galactose-binding domain-like
  • 49785 - Galactose-binding domain-like
  • 51445 - (Trans)glycosidases
  • 0Direct
    51445,140657,49785
  • 51445 - (Trans)glycosidases
  • 140657 - Hyaluronidase post-catalytic domain-like
  • 49785 - Galactose-binding domain-like
  • 0Direct
    63411,63411,63411
  • 63411 - LuxS/MPP-like metallohydrolase
  • 63411 - LuxS/MPP-like metallohydrolase
  • 63411 - LuxS/MPP-like metallohydrolase
  • 0Direct
    90188,53649,54060
  • 90188 - Somatomedin B domain
  • 53649 - Alkaline phosphatase-like
  • 54060 - His-Me finger endonucleases
  • 0Direct
    56568,47233,52799
  • 56568 - Non-globular alpha+beta subunits of globular proteins
  • 47233 - Bacterial GAP domain
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 0Direct
    143503,54001,49785
  • 143503 - PUG domain-like
  • 54001 - Cysteine proteinases
  • 49785 - Galactose-binding domain-like
  • 0Direct
    82895,82895,82895
  • 82895 - TSP-1 type 1 repeat
  • 82895 - TSP-1 type 1 repeat
  • 82895 - TSP-1 type 1 repeat
  • 0Direct
    52799,56091,50249
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 56091 - DNA ligase/mRNA capping enzyme, catalytic domain
  • 50249 - Nucleic acid-binding proteins
  • 0Direct
    46919,53098,50122
  • 46919 - N-terminal Zn binding domain of HIV integrase
  • 53098 - Ribonuclease H-like
  • 50122 - DNA-binding domain of retroviral integrase
  • 0Direct
    100895,56487,57424
  • 100895 - Kazal-type serine protease inhibitors
  • 56487 - SRCR-like
  • 57424 - LDL receptor-like module
  • 0Direct
    51445,51011,117100
  • 51445 - (Trans)glycosidases
  • 51011 - Glycosyl hydrolase domain
  • 117100 - Beta-galactosidase LacA, domain 3
  • 0Direct
    49854,49854,50494
  • 49854 - Spermadhesin, CUB domain
  • 49854 - Spermadhesin, CUB domain
  • 50494 - Trypsin-like serine proteases
  • 0Direct
    52540,48403,52540
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 48403 - Ankyrin repeat
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    55550,55550,50044
  • 55550 - SH2 domain
  • 55550 - SH2 domain
  • 50044 - SH3-domain
  • 0Direct
    69065,69065,54768
  • 69065 - RNase III domain-like
  • 69065 - RNase III domain-like
  • 54768 - dsRNA-binding domain-like
  • 0Direct
    53187,49464,53187
  • 53187 - Zn-dependent exopeptidases
  • 49464 - Carboxypeptidase regulatory domain-like
  • 53187 - Zn-dependent exopeptidases
  • 0Direct
    158702,52540,52540
  • 158702 - Sec63 N-terminal domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    57492,74650,51445
  • 57492 - Trefoil
  • 74650 - Galactose mutarotase-like
  • 51445 - (Trans)glycosidases
  • 0Direct
    50199,63748,50199
  • 50199 - Staphylococcal nuclease
  • 63748 - Tudor/PWWP/MBT
  • 50199 - Staphylococcal nuclease
  • 0Direct
    56672,53098,46919
  • 56672 - DNA/RNA polymerases
  • 53098 - Ribonuclease H-like
  • 46919 - N-terminal Zn binding domain of HIV integrase
  • 0Direct
    49785,51445,49344
  • 49785 - Galactose-binding domain-like
  • 51445 - (Trans)glycosidases
  • 49344 - CBD9-like
  • 0Direct
    55781,55781,109604
  • 55781 - GAF domain-like
  • 55781 - GAF domain-like
  • 109604 - HD-domain/PDEase-like
  • 0Direct
    82671,49854,49854
  • 82671 - SEA domain
  • 49854 - Spermadhesin, CUB domain
  • 49854 - Spermadhesin, CUB domain
  • 0Direct
    57603,57440,57440
  • 57603 - FnI-like domain
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 0Direct
    51445,64571,64571
  • 51445 - (Trans)glycosidases
  • 64571 - Cellulose docking domain, dockering
  • 64571 - Cellulose docking domain, dockering
  • 0Direct
    49464,53187,49464
  • 49464 - Carboxypeptidase regulatory domain-like
  • 53187 - Zn-dependent exopeptidases
  • 49464 - Carboxypeptidase regulatory domain-like
  • 0Direct
    47090,55486,57440
  • 47090 - PGBD-like
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 57440 - Kringle-like
  • 0Direct
    53955,54106,54106
  • 53955 - Lysozyme-like
  • 54106 - LysM domain
  • 54106 - LysM domain
  • 0Direct
    55486,49899,49599
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49599 - TRAF domain-like
  • 0Direct
    56672,53098,51283
  • 56672 - DNA/RNA polymerases
  • 53098 - Ribonuclease H-like
  • 51283 - dUTPase-like
  • 0Direct
    47943,47353,57756
  • 47943 - Retrovirus capsid protein, N-terminal core domain
  • 47353 - Retrovirus capsid dimerization domain-like
  • 57756 - Retrovirus zinc finger-like domains
  • 0Direct
    54637,54637,55961
  • 54637 - Thioesterase/thiol ester dehydrase-isomerase
  • 54637 - Thioesterase/thiol ester dehydrase-isomerase
  • 55961 - Bet v1-like
  • 0Direct
    49562,54236,54236
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 54236 - Ubiquitin-like
  • 54236 - Ubiquitin-like
  • 0Direct
    57756,57756,51283
  • 57756 - Retrovirus zinc finger-like domains
  • 57756 - Retrovirus zinc finger-like domains
  • 51283 - dUTPase-like
  • 0Direct
    54106,54106,54106
  • 54106 - LysM domain
  • 54106 - LysM domain
  • 54106 - LysM domain
  • 0Direct
    82671,57424,49854
  • 82671 - SEA domain
  • 57424 - LDL receptor-like module
  • 49854 - Spermadhesin, CUB domain
  • 0Direct
    52025,53187,47672
  • 52025 - PA domain
  • 53187 - Zn-dependent exopeptidases
  • 47672 - Transferrin receptor-like dimerisation domain
  • 0Direct
    51011,51445,51011
  • 51011 - Glycosyl hydrolase domain
  • 51445 - (Trans)glycosidases
  • 51011 - Glycosyl hydrolase domain
  • 0Direct
    50494,52540,56672
  • 50494 - Trypsin-like serine proteases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 56672 - DNA/RNA polymerases
  • 0Direct
    51445,49303,49303
  • 51445 - (Trans)glycosidases
  • 49303 - beta-Galactosidase/glucuronidase domain
  • 49303 - beta-Galactosidase/glucuronidase domain
  • 0Direct
    49854,49854,57424
  • 49854 - Spermadhesin, CUB domain
  • 49854 - Spermadhesin, CUB domain
  • 57424 - LDL receptor-like module
  • 0Direct
    52540,52540,47370
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 47370 - Bromodomain
  • 0Direct
    49854,57424,57424
  • 49854 - Spermadhesin, CUB domain
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 0Direct
    89043,50494,56672
  • 89043 - Soluble domain of poliovirus core protein 3a
  • 50494 - Trypsin-like serine proteases
  • 56672 - DNA/RNA polymerases
  • 0Direct
    46785,158702,52540
  • 46785 - "Winged helix" DNA-binding domain
  • 158702 - Sec63 N-terminal domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    143076,101816,144246
  • 143076 - Coronavirus NSP8-like
  • 101816 - Replicase NSP9
  • 144246 - Coronavirus NSP10-like
  • 0Direct
    53067,53067,109604
  • 53067 - Actin-like ATPase domain
  • 53067 - Actin-like ATPase domain
  • 109604 - HD-domain/PDEase-like
  • 0Direct
    50199,50199,50199
  • 50199 - Staphylococcal nuclease
  • 50199 - Staphylococcal nuclease
  • 50199 - Staphylococcal nuclease
  • 0Direct
    52540,56712,51294
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 56712 - Prokaryotic type I DNA topoisomerase
  • 51294 - Hedgehog/intein (Hint) domain
  • 0Direct
    50447,54980,54980
  • 50447 - Translation proteins
  • 54980 - EF-G C-terminal domain-like
  • 54980 - EF-G C-terminal domain-like
  • 0Direct
    50729,56024,56024
  • 50729 - PH domain-like
  • 56024 - Phospholipase D/nuclease
  • 56024 - Phospholipase D/nuclease
  • 0Direct
    49785,81296,48208
  • 49785 - Galactose-binding domain-like
  • 81296 - E set domains
  • 48208 - Six-hairpin glycosidases
  • 0Direct
    58091,49899,50386
  • 58091 - Clostridium neurotoxins, "coiled-coil" domain
  • 49899 - Concanavalin A-like lectins/glucanases
  • 50386 - STI-like
  • 0Direct
    56672,52540,52540
  • 56672 - DNA/RNA polymerases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    54160,54160,52540
  • 54160 - Chromo domain-like
  • 54160 - Chromo domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    52540,52540,47819
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 47819 - HRDC-like
  • 0Direct
    57440,57440,57440
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 0Direct
    56487,57424,57424
  • 56487 - SRCR-like
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 0Direct
    53098,46919,53098
  • 53098 - Ribonuclease H-like
  • 46919 - N-terminal Zn binding domain of HIV integrase
  • 53098 - Ribonuclease H-like
  • 0Direct
    52540,54980,54980
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 54980 - EF-G C-terminal domain-like
  • 54980 - EF-G C-terminal domain-like
  • 0Direct
    51445,51011,49265
  • 51445 - (Trans)glycosidases
  • 51011 - Glycosyl hydrolase domain
  • 49265 - Fibronectin type III
  • 0Direct
    56672,53098,53098
  • 56672 - DNA/RNA polymerases
  • 53098 - Ribonuclease H-like
  • 53098 - Ribonuclease H-like
  • 0Direct
    55781,55781,55781
  • 55781 - GAF domain-like
  • 55781 - GAF domain-like
  • 55781 - GAF domain-like
  • 0Direct
    50692,54585,52540
  • 50692 - ADC-like
  • 54585 - Cdc48 domain 2-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    50630,56672,53098
  • 50630 - Acid proteases
  • 56672 - DNA/RNA polymerases
  • 53098 - Ribonuclease H-like
  • 0Direct
    51445,49344,49344
  • 51445 - (Trans)glycosidases
  • 49344 - CBD9-like
  • 49344 - CBD9-like
  • 0Direct
    57424,49854,49899
  • 57424 - LDL receptor-like module
  • 49854 - Spermadhesin, CUB domain
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0Direct
    54001,49758,47473
  • 54001 - Cysteine proteinases
  • 49758 - Calpain large subunit, middle domain (domain III)
  • 47473 - EF-hand
  • 0Direct
    57630,57184,50494
  • 57630 - GLA-domain
  • 57184 - Growth factor receptor domain
  • 50494 - Trypsin-like serine proteases
  • 0Direct
    57424,57424,50494
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 50494 - Trypsin-like serine proteases
  • 0Direct
    55545,51445,81296
  • 55545 - beta-N-acetylhexosaminidase-like domain
  • 51445 - (Trans)glycosidases
  • 81296 - E set domains
  • 0Direct
    47836,47943,47353
  • 47836 - Retroviral matrix proteins
  • 47943 - Retrovirus capsid protein, N-terminal core domain
  • 47353 - Retrovirus capsid dimerization domain-like
  • 0Direct
    54768,54768,54768
  • 54768 - dsRNA-binding domain-like
  • 54768 - dsRNA-binding domain-like
  • 54768 - dsRNA-binding domain-like
  • 0Direct
    51338,51556,51338
  • 51338 - Composite domain of metallo-dependent hydrolases
  • 51556 - Metallo-dependent hydrolases
  • 51338 - Composite domain of metallo-dependent hydrolases
  • 0Direct
    50630,56672,46919
  • 50630 - Acid proteases
  • 56672 - DNA/RNA polymerases
  • 46919 - N-terminal Zn binding domain of HIV integrase
  • 0Direct
    88633,50494,52540
  • 88633 - Positive stranded ssRNA viruses
  • 50494 - Trypsin-like serine proteases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    54160,52540,52540
  • 54160 - Chromo domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    57535,53300,50494
  • 57535 - Complement control module/SCR domain
  • 53300 - vWA-like
  • 50494 - Trypsin-like serine proteases
  • 0Direct
    57756,50630,56672
  • 57756 - Retrovirus zinc finger-like domains
  • 50630 - Acid proteases
  • 56672 - DNA/RNA polymerases
  • 0Direct
    49899,49854,57424
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49854 - Spermadhesin, CUB domain
  • 57424 - LDL receptor-like module
  • 0Direct
    88633,88633,88633
  • 88633 - Positive stranded ssRNA viruses
  • 88633 - Positive stranded ssRNA viruses
  • 88633 - Positive stranded ssRNA viruses
  • 0Direct
    53300,100939,101420
  • 53300 - vWA-like
  • 100939 - SPOC domain-like
  • 101420 - C-terminal domain of Ku80
  • 0Direct
    50249,47781,46929
  • 50249 - Nucleic acid-binding proteins
  • 47781 - RuvA domain 2-like
  • 46929 - DNA helicase RuvA subunit, C-terminal domain
  • 0Direct
    53092,53092,55920
  • 53092 - Creatinase/prolidase N-terminal domain
  • 53092 - Creatinase/prolidase N-terminal domain
  • 55920 - Creatinase/aminopeptidase
  • 0Direct
    57630,57440,57440
  • 57630 - GLA-domain
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 0Direct
    54585,52540,52540
  • 54585 - Cdc48 domain 2-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    48592,54849,52029
  • 48592 - GroEL equatorial domain-like
  • 54849 - GroEL-intermediate domain like
  • 52029 - GroEL apical domain-like
  • 0Direct
    52540,49899,52540
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 49899 - Concanavalin A-like lectins/glucanases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    51197,52540,56672
  • 51197 - Clavaminate synthase-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 56672 - DNA/RNA polymerases
  • 0Direct
    49854,57535,57535
  • 49854 - Spermadhesin, CUB domain
  • 57535 - Complement control module/SCR domain
  • 57535 - Complement control module/SCR domain
  • 0Direct
    55486,58091,49899
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 58091 - Clostridium neurotoxins, "coiled-coil" domain
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0Direct
    90188,90188,53649
  • 90188 - Somatomedin B domain
  • 90188 - Somatomedin B domain
  • 53649 - Alkaline phosphatase-like
  • 0Direct
    81296,51445,54556
  • 81296 - E set domains
  • 51445 - (Trans)glycosidases
  • 54556 - Chitinase insertion domain
  • 0Direct
    56371,50370,50370
  • 56371 - Ribosome inactivating proteins (RIP)
  • 50370 - Ricin B-like lectins
  • 50370 - Ricin B-like lectins
  • 0Direct
    81761,53474,49785
  • 81761 - X-Prolyl dipeptidyl aminopeptidase PepX, N-terminal domain
  • 53474 - alpha/beta-Hydrolases
  • 49785 - Galactose-binding domain-like
  • 0Direct
    51445,52317,51011
  • 51445 - (Trans)glycosidases
  • 52317 - Class I glutamine amidotransferase-like
  • 51011 - Glycosyl hydrolase domain
  • 0Direct
    88713,88688,74650
  • 88713 - Glycoside hydrolase/deacetylase
  • 88688 - Families 57/38 glycoside transferase middle domain
  • 74650 - Galactose mutarotase-like
  • 0.00000000003613Direct
    52283,51735,52283
  • 52283 - Formate/glycerate dehydrogenase catalytic domain-like
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 52283 - Formate/glycerate dehydrogenase catalytic domain-like
  • 0.000000000291Direct
    52540,52540,56672
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 56672 - DNA/RNA polymerases
  • 0.00000009293Direct
    48726,49265,49265
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 49265 - Fibronectin type III
  • 0.000001491Direct
    52335,51556,51338
  • 52335 - Methylglyoxal synthase-like
  • 51556 - Metallo-dependent hydrolases
  • 51338 - Composite domain of metallo-dependent hydrolases
  • 0.000003775Direct
    51445,51011,49452
  • 51445 - (Trans)glycosidases
  • 51011 - Glycosyl hydrolase domain
  • 49452 - Starch-binding domain-like
  • 0.00001819Direct
    51735,47336,53474
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 47336 - ACP-like
  • 53474 - alpha/beta-Hydrolases
  • 0.00008794Direct
    56059,52335,51556
  • 56059 - Glutathione synthetase ATP-binding domain-like
  • 52335 - Methylglyoxal synthase-like
  • 51556 - Metallo-dependent hydrolases
  • 0.0001092Direct
    54236,47031,50729
  • 54236 - Ubiquitin-like
  • 47031 - Second domain of FERM
  • 50729 - PH domain-like
  • 0.0005272Direct
    52540,52540,52540
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.002047Inherited
    52540,51294,55608
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 51294 - Hedgehog/intein (Hint) domain
  • 55608 - Homing endonucleases
  • 0.002585Inherited
    52317,52440,56059
  • 52317 - Class I glutamine amidotransferase-like
  • 52440 - PreATP-grasp domain
  • 56059 - Glutathione synthetase ATP-binding domain-like
  • 0.00317Inherited
    52021,52317,52440
  • 52021 - Carbamoyl phosphate synthetase, small subunit N-terminal domain
  • 52317 - Class I glutamine amidotransferase-like
  • 52440 - PreATP-grasp domain
  • 0.00317Inherited
    48726,48726,49265
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 0.009496Inherited
    81296,51445,51011
  • 81296 - E set domains
  • 51445 - (Trans)glycosidases
  • 51011 - Glycosyl hydrolase domain
  • 0.0459Inherited
    109604,81301,81271
  • 109604 - HD-domain/PDEase-like
  • 81301 - Nucleotidyltransferase
  • 81271 - TGS-like
  • 0.06171Inherited
    50129,51735,51735
  • 50129 - GroES-like
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 0.1266Inherited
    51735,51735,47336
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 47336 - ACP-like
  • 0.741Inherited
    52440,56059,48108
  • 52440 - PreATP-grasp domain
  • 56059 - Glutathione synthetase ATP-binding domain-like
  • 48108 - Carbamoyl phosphate synthetase, large subunit connection domain
  • 1Inherited
    81660,56784,81665
  • 81660 - Metal cation-transporting ATPase, ATP-binding domain N
  • 56784 - HAD-like
  • 81665 - Calcium ATPase, transmembrane domain M
  • 1Inherited
    48726,48726,48726
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 1Inherited
    56059,48108,52440
  • 56059 - Glutathione synthetase ATP-binding domain-like
  • 48108 - Carbamoyl phosphate synthetase, large subunit connection domain
  • 52440 - PreATP-grasp domain
  • 1Inherited
    48108,52440,56059
  • 48108 - Carbamoyl phosphate synthetase, large subunit connection domain
  • 52440 - PreATP-grasp domain
  • 56059 - Glutathione synthetase ATP-binding domain-like
  • 1Inherited
    52518,52467,52518
  • 52518 - Thiamin diphosphate-binding fold (THDP-binding)
  • 52467 - DHS-like NAD/FAD-binding domain
  • 52518 - Thiamin diphosphate-binding fold (THDP-binding)
  • 1Inherited
    52440,56059,52335
  • 52440 - PreATP-grasp domain
  • 56059 - Glutathione synthetase ATP-binding domain-like
  • 52335 - Methylglyoxal synthase-like
  • 1Inherited


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