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Enzyme Commission (EC): Hydrolases

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Root: EC Hierarchy (from IntEnz release 70)

Shortest distance to current term (+ for parents, - for children) EC term [EC ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ 1:   root [root] <7>
0:   Hydrolases [3] <13>(406|681) (406|427|219)
- 1:   Acting on ester bonds [3.1] <23>(158|227) (158|125|55)
- 1:   Acting on peptide bonds (peptidases) [3.4] <19>(114|167) (114|130|72)
- 1:   Acting on carbon-nitrogen bonds, other than peptide bonds [3.5] <6>(70|103) (70|37|18)
- 1:   Acting on acid anhydrides [3.6] <5>(109|138) (109|111|78)
- 1:   Glycosylases [3.2] <3>(67|118) (67|74|35)
- 1:   Acting on ether bonds [3.3] <2>(9|8) (9|6|2)
- 1:   Acting on halide bonds [3.8] <2>(3|3) (3|0|0)
- 1:   Acting on carbon-carbon bonds [3.7] <1>(9|10) (9|4|1)
- 1:   Acting on carbon-phosphorus bonds [3.11] <1>(2|2) (2|0|0)
- 1:   Acting on carbon-sulfur bonds [3.13] <1>(2|2) (2|0|0)
- 1:   Acting on phosphorus-nitrogen bonds [3.9] <1>(1|1) (1|0|0)
- 1:   Acting on sulfur-nitrogen bonds [3.10] <1>(0|0) (0|0|0)
- 1:   Acting on sulfur-sulfur bonds [3.12] <1>(0|0) (0|0|0)


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
DUSP-like0Direct
Inorganic pyrophosphatase0Direct
HisI-like0Direct
alpha/beta-Hydrolases0Direct
cAMP-binding domain-like0Direct
Type X cellulose binding domain, CBDX0Direct
SARS Nsp1-like0Direct
C-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
Penicillin-binding protein associated domain0Direct
Carbohydrate phosphatase0Direct
CheY-like0Direct
Acid proteases0Direct
PP2C-like0Direct
Transferrin receptor-like dimerisation domain0Direct
AlbA-like0Direct
EGF/Laminin0Direct
Rnp2-like0Direct
Creatininase0Direct
PLC-like phosphodiesterases0Direct
Peptidase/esterase 'gauge' domain0Direct
Methylesterase CheB, C-terminal domain0Direct
Nitrous oxide reductase, N-terminal domain0Direct
Urease, gamma-subunit0Direct
Urease, beta-subunit0Direct
SPOC domain-like0Direct
Calcium ATPase, transduction domain A0Direct
MCP/YpsA-like0Direct
Positive stranded ssRNA viruses0Direct
DTD-like0Direct
Bacterial exopeptidase dimerisation domain0Direct
Soluble domain of poliovirus core protein 3a0Direct
(Trans)glycosidases0Direct
Cellulose-binding domain0Direct
RuvA domain 2-like0Direct
HAD-like0Direct
Ribonuclease H-like0Direct
Ribonuclease Rh-like0Direct
Cap-Gly domain0Direct
Creatinase/aminopeptidase0Direct
C2 domain (Calcium/lipid-binding domain, CaLB)0Direct
Aminoacid dehydrogenase-like, N-terminal domain0Direct
Sortase0Direct
Acylphosphatase/BLUF domain-like0Direct
Plant invertase/pectin methylesterase inhibitor0Direct
Cystatin/monellin0Direct
Invertebrate chitin-binding proteins0Direct
Origin of replication-binding domain, RBD-like0Direct
SurE-like0Direct
HRDC-like0Direct
Type I dockerin domain0Direct
Archaeal IMP cyclohydrolase PurO0Direct
Somatomedin B domain0Direct
FabD/lysophospholipase-like0Direct
Peptide deformylase0Direct
Carbohydrate-binding domain0Direct
Rof/RNase P subunit-like0Direct
GroEL equatorial domain-like0Direct
Metallo-dependent hydrolases0Direct
Seven-hairpin glycosidases0Direct
Purple acid phosphatase, N-terminal domain0Direct
Bacterial GAP domain0Direct
AN1-like Zinc finger0Direct
SGNH hydrolase0Direct
Cdc48 domain 2-like0Direct
P-loop containing nucleoside triphosphate hydrolases0Direct
Voltage-gated potassium channels0Direct
Microbial ribonucleases0Direct
Tetrahydrobiopterin biosynthesis enzymes-like0Direct
Trypsin-like serine proteases0Direct
beta-lactamase/transpeptidase-like0Direct
PKD domain0Direct
DPP6 N-terminal domain-like0Direct
Glycosyl hydrolases family 6, cellulases0Direct
Spermadhesin, CUB domain0Direct
SEA domain0Direct
beta-N-acetylhexosaminidase-like domain0Direct
Heat shock protein 70kD (HSP70), peptide-binding domain0Direct
Peptidyl-tRNA hydrolase-like0Direct
ADP-ribosylglycohydrolase0Direct
Penicillin binding protein dimerisation domain0Direct
Peptidyl-tRNA hydrolase domain-like0Direct
LD-carboxypeptidase A C-terminal domain-like0Direct
Hemopexin-like domain0Direct
DNA/RNA polymerases0Direct
Nucleoside hydrolase0Direct
Glycosyl hydrolase domain0Direct
Zn-dependent exopeptidases0Direct
Pyrrolidone carboxyl peptidase (pyroglutamate aminopeptidase)0Direct
5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain0Direct
Kringle-like0Direct
HIT-like0Direct
RibA-like0Direct
Carbohydrate binding domain0Direct
CNF1/YfiH-like putative cysteine hydrolases0Direct
Cytidine deaminase-like0Direct
LysM domain0Direct
Invasin/intimin cell-adhesion fragments0Direct
Prokaryotic SH3-related domain0Direct
Rap30/74 interaction domains0Direct
Putative cyclase0Direct
Six-hairpin glycosidases0Direct
Influenza hemagglutinin (stalk)0Direct
Dextranase, N-terminal domain0Direct
Autotransporter0Direct
Heat shock protein 70kD (HSP70), C-terminal subdomain0Direct
Calpain large subunit, middle domain (domain III)0Direct
Sulfolobus fructose-1,6-bisphosphatase-like0Direct
Beta-galactosidase LacA, domain 30Direct
C-terminal domain of Ku800Direct
CinA-like0Direct
Hedgehog/DD-peptidase0Direct
Methylglyoxal synthase-like0Direct
Clostridium neurotoxins, "coiled-coil" domain0Direct
AbfB domain0Direct
all-alpha NTP pyrophosphatases0Direct
Composite domain of metallo-dependent hydrolases0Direct
N-terminal domain of MutM-like DNA repair proteins0Direct
Anthrax protective antigen0Direct
Cysteine proteinases0Direct
Phospholipase A2, PLA20Direct
CbiG N-terminal domain-like0Direct
Protease propeptides/inhibitors0Direct
Holliday junction resolvase RusA0Direct
Coronavirus NSP7-like0Direct
Fumarylacetoacetate hydrolase, FAH, N-terminal domain0Direct
SpoIIaa-like0Direct
N-acetylmuramoyl-L-alanine amidase-like0Direct
Methenyltetrahydromethanopterin cyclohydrolase0Direct
Creatinase/prolidase N-terminal domain0Direct
Nudix0Direct
Calcium ATPase, transmembrane domain M0Direct
DNase I-like0Direct
Apyrase0Direct
Sec-C motif0Direct
Arabinanase/levansucrase/invertase0Direct
Blood coagulation inhibitor (disintegrin)0Direct
dsRNA-binding domain-like0Direct
ComB-like0Direct
Dcp2 domain-like0Direct
Viral protein domain0Direct
Cellulose docking domain, dockering0Direct
HMA, heavy metal-associated domain0Direct
Sialidases0Direct
DNA helicase RuvA subunit, C-terminal domain0Direct
Replicase NSP90Direct
Plant lectins/antimicrobial peptides0Direct
Peptidylarginine deiminase Pad4, middle domain0Direct
Coronavirus NSP8-like0Direct
Glucocorticoid receptor-like (DNA-binding domain)0Direct
DNA-binding domain of retroviral integrase0Direct
XseB-like0Direct
Uracil-DNA glycosylase-like0Direct
Collagen-binding domain0Direct
RNase A-like0Direct
ITPase-like0Direct
EF-G C-terminal domain-like0Direct
Viral glycoprotein, central and dimerisation domains0Direct
Retrovirus zinc finger-like domains0Direct
ssDNA viruses0Direct
Pentein0Direct
PDZ domain-like0Direct
C-terminal domain of PLC-beta0Direct
Herpes virus serine proteinase, assemblin0Direct
beta-Galactosidase/glucuronidase domain0Direct
DHH phosphoesterases0Direct
MOP-like0Direct
Flavivirus capsid protein C0Direct
Phospholipase C/P1 nuclease0Direct
Acetamidase/Formamidase-like0Direct
Toprim domain0Direct
Retroviral matrix proteins0Direct
Metal cation-transporting ATPase, ATP-binding domain N0Direct
Saposin0Direct
N-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
Metallo-dependent phosphatases0Direct
Metalloproteases ("zincins"), catalytic domain0Direct
Retrovirus capsid dimerization domain-like0Direct
N-terminal domain of DnaB helicase0Direct
Formate/glycerate dehydrogenase catalytic domain-like0Direct
Pectin lyase-like0Direct
RNase III domain-like0Direct
R3H domain0Direct
Sec63 N-terminal domain-like0Direct
Rhomboid-like0Direct
dUTPase-like0Direct
ABC transporter transmembrane region0Direct
DNA primase core0Direct
JAB1/MPN domain0Direct
Beta-D-glucan exohydrolase, C-terminal domain0Direct
Thermostable phytase (3-phytase)0Direct
Protein serine/threonine phosphatase 2C, C-terminal domain0Direct
Concanavalin A-like lectins/glucanases0Direct
Acid phosphatase/Vanadium-dependent haloperoxidase0Direct
CRAL/TRIO N-terminal domain0Direct
Metallo-hydrolase/oxidoreductase0Direct
N-terminal nucleophile aminohydrolases (Ntn hydrolases)0Direct
Macro domain-like0Direct
"Winged helix" DNA-binding domain0Direct
BRK domain-like0Direct
Subtilisin-like0Direct
PAZ domain0Direct
Oligoxyloglucan reducing end-specific cellobiohydrolase0Direct
LmbE-like0Direct
Carbon-nitrogen hydrolase0Direct
N-terminal Zn binding domain of HIV integrase0Direct
Glycoside hydrolase/deacetylase0Direct
CobE/GbiG C-terminal domain-like0Direct
Hyaluronidase post-catalytic domain-like0Direct
Kazal-type serine protease inhibitors0Direct
Lysozyme-like0Direct
CYTH-like phosphatases0Direct
HybD-like0Direct
(Phosphotyrosine protein) phosphatases II0Direct
L9 N-domain-like0Direct
Trefoil0Direct
Initiation factor IF2/eIF5b, domain 30Direct
PGBD-like0Direct
EndoU-like0Direct
Viral leader polypeptide zinc finger0Direct
Glutaminase/Asparaginase0Direct
Retrovirus capsid protein, N-terminal core domain0Direct
LigT-like0Direct
AF0625-like0Direct
TSP-1 type 1 repeat0Direct
Chitinase insertion domain0Direct
Carboxypeptidase regulatory domain-like0Direct
TMV-like viral coat proteins0Direct
Isochorismatase-like hydrolases0Direct
Leukotriene A4 hydrolase N-terminal domain0Direct
Aminopeptidase/glucanase lid domain0Direct
His-Me finger endonucleases0Direct
OMPT-like0Direct
GLA-domain0Direct
Ribosome inactivating proteins (RIP)0Direct
Galactose-binding domain-like0Direct
STI-like0Direct
Putative isomerase YbhE0Direct
Coronavirus NSP10-like0Direct
Outer membrane phospholipase A (OMPLA)0Direct
Restriction endonuclease-like0Direct
LexA/Signal peptidase0Direct
ClpP/crotonase0Direct
Peptidyl-tRNA hydrolase II0Direct
Caspase-like0Direct
Complement control module/SCR domain0Direct
D-aminopeptidase, middle and C-terminal domains0Direct
Transthyretin (synonym: prealbumin)0Direct
Arginase/deacetylase0Direct
S13-like H2TH domain0Direct
mRNA decapping enzyme DcpS N-terminal domain0Direct
Families 57/38 glycoside transferase middle domain0Direct
NSP3A-like0Direct
Galactose mutarotase-like0Direct
Phage fibre proteins0Direct
X-Prolyl dipeptidyl aminopeptidase PepX, N-terminal domain0Direct
Dipeptidyl peptidase I (cathepsin C), exclusion domain0Direct
Calcium-dependent phosphotriesterase0.000000000000193Direct
vWA-like0.0000000000002307Direct
Xylose isomerase-like0.0000000000003131Direct
EAL domain-like0.000000000002522Direct
E set domains0.000000000005263Direct
EF-hand0.000000000008748Direct
HD-domain/PDEase-like0.000000000009453Direct
PH domain-like0.0000000000204Direct
Purine and uridine phosphorylases0.0000000002206Direct
Phosphotyrosine protein phosphatases I0.000000000505Direct
Translation proteins0.00000000164Direct
Staphylococcal nuclease0.000000002804Direct
PA domain0.000000006786Direct
Ubiquitin-like0.00000003349Direct
Tudor/PWWP/MBT0.0000000467Direct
UBA-like0.00000005594Direct
Hairpin loop containing domain-like0.0000002072Direct
LDL receptor-like module0.0000002072Direct
YjgF-like0.0000003186Direct
Hedgehog/intein (Hint) domain0.0000004296Direct
GAF domain-like0.0000005116Direct
DEATH domain0.0000006539Direct
Phospholipase D/nuclease0.000001802Direct
N-(deoxy)ribosyltransferase-like0.000004338Direct
Lipase/lipooxygenase domain (PLAT/LH2 domain)0.000004902Direct
Starch-binding domain-like0.000008141Direct
Fibronectin type III0.00001069Direct
MIT domain0.0000109Direct
Ribosomal protein S5 domain 2-like0.00001364Direct
PUG domain-like0.00001433Direct
beta-Roll0.00001511Direct
DNA clamp0.00003675Direct
CBD9-like0.00003675Direct
HCP-like0.00005566Direct
DEK C-terminal domain0.00005762Direct
PH0987 N-terminal domain-like0.0001634Direct
HIT/MYND zinc finger-like0.0001926Direct
Phosphoglycerate mutase-like0.0003061Direct
FnI-like domain0.0004939Direct
Homing endonucleases0.0006142Direct
NagB/RpiA/CoA transferase-like0.0006423Direct
Barwin-like endoglucanases0.0006507Direct
GroEL-intermediate domain like0.0008096Direct
Ricin B-like lectins0.002029Inherited
SRCR-like0.002031Inherited
Chromo domain-like0.002284Inherited
GTPase activation domain, GAP0.002831Inherited
Cell wall binding repeat0.00319Inherited
Ras GEF0.003427Inherited
SAP domain0.004606Inherited
Integrin alpha N-terminal domain0.006775Inherited
WD40 repeat-like0.007932Inherited
F-box domain0.0128Inherited
PX domain0.01481Inherited
FAH0.01635Inherited
GroEL apical domain-like0.02472Inherited
Chaperone J-domain0.03105Inherited
RNA-binding domain, RBD0.04443Inherited
DNA-glycosylase0.05594Inherited
Second domain of FERM0.05783Inherited
C-terminal (heme d1) domain of cytochrome cd1-nitrite reductase0.05893Inherited
Duplicated hybrid motif0.05999Inherited
Rhodanese/Cell cycle control phosphatase0.07225Inherited
TATA-box binding protein-like0.1423Inherited
SMAD/FHA domain0.1431Inherited
Class I glutamine amidotransferase-like0.1433Inherited
Ran binding protein zinc finger-like0.1458Inherited
HSP20-like chaperones0.1944Inherited
CRAL/TRIO domain0.195Inherited
PHP domain-like0.2006Inherited
beta-sandwich domain of Sec23/240.2711Inherited
YrdC/RibB0.3572Inherited
TRAF domain-like0.4018Inherited
NTF2-like0.4119Inherited
Ankyrin repeat0.6581Inherited
Non-globular alpha+beta subunits of globular proteins0.6768Inherited
post-AAA+ oligomerization domain-like0.7342Inherited
Prokaryotic type I DNA topoisomerase0.971Inherited
S15/NS1 RNA-binding domain0.9837Inherited
Growth factor receptor domain1Inherited
FMT C-terminal domain-like1Inherited
TPR-like1Inherited
Aspartate/ornithine carbamoyltransferase1Inherited
Carbamoyl phosphate synthetase, large subunit connection domain1Inherited
Dihydrofolate reductase-like1Inherited
Thioesterase/thiol ester dehydrase-isomerase1Inherited
RmlC-like cupins1Inherited
Nucleotidyltransferase1Inherited
L30e-like1Inherited
Clavaminate synthase-like1Inherited
Immunoglobulin1Inherited
UDP-Glycosyltransferase/glycogen phosphorylase1Inherited
Nucleic acid-binding proteins1Inherited
LDH C-terminal domain-like1Inherited
Kelch motif1Inherited
SAM/Pointed domain1Inherited
RING/U-box1Inherited
Thioredoxin-like1Inherited
PHP14-like1Inherited
Terpenoid synthases1Inherited
CBS-domain pair1Inherited
Nucleotide cyclase1Inherited
Alkaline phosphatase-like1Inherited
Probable ACP-binding domain of malonyl-CoA ACP transacylase1Inherited
Periplasmic binding protein-like II1Inherited
ADP-ribosylation1Inherited
beta-carbonic anhydrase, cab1Inherited
NAD(P)-binding Rossmann-fold domains1Inherited
Amidase signature (AS) enzymes1Inherited
ACT-like1Inherited
ADC-like1Inherited
ARM repeat1Inherited
TGS-like1Inherited
Quinoprotein alcohol dehydrogenase-like1Inherited
Actin-like ATPase domain1Inherited
GroES-like1Inherited
CCCH zinc finger1Inherited
WW domain1Inherited
Acyl-CoA N-acyltransferases (Nat)1Inherited
Thiolase-like1Inherited
AraD/HMP-PK domain-like1Inherited
Cyclophilin-like1Inherited
Bet v1-like1Inherited
FYVE/PHD zinc finger1Inherited
DNA ligase/mRNA capping enzyme, catalytic domain1Inherited
Inosine monophosphate dehydrogenase (IMPDH)1Inherited
Thiamin diphosphate-binding fold (THDP-binding)1Inherited
PUA domain-like1Inherited
Formyltransferase1Inherited
Class II aaRS ABD-related1Inherited
S-adenosyl-L-methionine-dependent methyltransferases1Inherited
PIN domain-like1Inherited
Heme oxygenase-like1Inherited
Terpenoid cyclases/Protein prenyltransferases1Inherited
Carbamoyl phosphate synthetase, small subunit N-terminal domain1Inherited
PreATP-grasp domain1Inherited
ACP-like1Inherited
Phosphoenolpyruvate/pyruvate domain1Inherited
DHS-like NAD/FAD-binding domain1Inherited
PYP-like sensor domain (PAS domain)1Inherited
Tryptophan synthase beta subunit-like PLP-dependent enzymes1Inherited
L domain-like1Inherited
Cupredoxins1Inherited
Carbonic anhydrase1Inherited
PLP-dependent transferases1Inherited
SH2 domain1Inherited
LuxS/MPP-like metallohydrolase1Inherited
SH3-domain1Inherited
Bromodomain1Inherited
Methylated DNA-protein cysteine methyltransferase, C-terminal domain1Inherited


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Family

(show details)
SCOP termFDR (all)Annotation (direct or inherited)
VanX-like0Direct
M48USP-like0Direct
PLC-like (P variant)0Direct
beta-Galactosidase/glucuronidase domain0Direct
N-acetylglucosamine-6-phosphate deacetylase, NagA, catalytic domain0Direct
Prokaryotic proteases0Direct
Class I alpha-1;2-mannosidase, catalytic domain0Direct
CRAL/TRIO domain0Direct
Viral cysteine protease of trypsin fold0Direct
Aminopeptidase/glucanase lid domain0Direct
ADP-ribosylglycohydrolase0Direct
Mug-like0Direct
GroEL-like chaperone, intermediate domain0Direct
Leucine aminopeptidase (Aminopeptidase A), N-terminal domain0Direct
NagZ-like0Direct
SEA domain0Direct
Sec-C motif0Direct
Sec63 C-terminal domain-like0Direct
Alkaline phosphatase0Direct
DUSP, domain in ubiquitin-specific proteases0Direct
Penta-EF-hand proteins0Direct
Sec63 N-terminal domain0Direct
Zf-UBP0Direct
Glycosyl hydrolases family 6, cellulases0Direct
Purple acid phosphatase-like0Direct
PP2C-like0Direct
Type II chitinase0Direct
Histidinol phosphatase-like0Direct
1,4-beta-N-acetylmuraminidase0Direct
Manganese-dependent inorganic pyrophosphatase (family II)0Direct
Gingipain R (RgpB), N-terminal domain0Direct
LysM domain0Direct
Plant cytotoxins0Direct
Methionine aminopeptidase, insert domain0Direct
Acylamino-acid-releasing enzyme, C-terminal donain0Direct
Thioesterases0Direct
Peptidylarginine deiminase Pad4, N-terminal domain0Direct
Tandem AAA-ATPase domain0Direct
PepX catalytic domain-like0Direct
Heat shock protein 70kD (HSP70), C-terminal subdomain0Direct
Zinc protease0Direct
Collagen-binding domain0Direct
Class II viral fusion proteins C-terminal domain0Direct
Gastric lipase0Direct
Phage lysozyme0Direct
D-aminoacylase0Direct
Fibronectin type II module0Direct
Cellulose docking domain, dockering0Direct
Beta-D-xylosidase C-terminal domain-like0Direct
Reprolysin-like0Direct
Replicase NSP90Direct
RNB domain-like0Direct
Endonuclease IV0Direct
Insect phospholipase A20Direct
Dimethylarginine dimethylaminohydrolase DDAH0Direct
Mammalian PLC0Direct
LamB/YcsF-like0Direct
RNase P protein0Direct
Esterase0Direct
Fungal ribonucleases0Direct
NADH pyrophosphatase0Direct
Virulence factor P.69 pertactin0Direct
MazG-like0Direct
AICAR transformylase domain of bifunctional purine biosynthesis enzyme ATIC0Direct
Somatomedin B domain0Direct
NLI interacting factor-like phosphatase0Direct
Putative acetylxylan esterase-like0Direct
Extended AAA-ATPase domain0Direct
Cytidine deaminase0Direct
Adenosine/AMP deaminase0Direct
Fibronectin type I module0Direct
Eukaryotic proteases0Direct
Carboxypeptidase regulatory domain0Direct
S-adenosylhomocystein hydrolase0Direct
RecU-like0Direct
Hevein-like agglutinin (lectin) domain0Direct
PBP5 C-terminal domain-like0Direct
DNA/RNA non-specific endonuclease0Direct
DNA helicase RuvA subunit, N-terminal domain0Direct
Inositol monophosphatase/fructose-1,6-bisphosphatase-like0Direct
alpha-subunit of urease, catalytic domain0Direct
Heat shock protein 70kD (HSP70), peptide-binding domain0Direct
C-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
Middle domain of MutM-like DNA repair proteins0Direct
Peptidoglycan binding domain, PGBD0Direct
Thermostable phytase (3-phytase)0Direct
DNA-binding domain from rap300Direct
Alpha-toxin, C-terminal domain0Direct
Fumarylacetoacetate hydrolase, FAH, N-terminal domain0Direct
Cellulose-binding domain family II0Direct
N-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
Phosphonoacetate hydrolase0Direct
Amylase, catalytic domain0Direct
X-Prolyl dipeptidyl aminopeptidase PepX, N-terminal domain0Direct
dUTPase-like0Direct
Acetylcholinesterase-like0Direct
YdjC-like0Direct
Glutaminase0Direct
Caliciviridae-like VP0Direct
Family 1 of glycosyl hydrolase0Direct
MutY C-terminal domain-like0Direct
Initiation factor IF2/eIF5b, domain 30Direct
HAD-related0Direct
Actin/HSP700Direct
RecG "wedge" domain0Direct
CAF1-like ribonuclease0Direct
Predicted hydrolases Cof0Direct
Colipase-binding domain0Direct
GpdQ-like0Direct
Glycosyl hydrolases family 32 N-terminal domain0Direct
ADPRibase-Mn-like0Direct
Bacterial lipase0Direct
Coronavirus NSP7-like0Direct
D-aminoacylase, catalytic domain0Direct
Ubiquitin carboxyl-terminal hydrolase UCH-L0Direct
Histone deacetylase, HDAC0Direct
Trypanosoma sialidase, C-terminal domain0Direct
Reverse transcriptase0Direct
YicI catalytic domain-like0Direct
Neurolysin-like0Direct
Leishmanolysin0Direct
Calpain large subunit, catalytic domain (domain II)0Direct
Hemagglutinin domain of haemagglutinin-esterase-fusion glycoprotein HEF10Direct
N-acetylmuramoyl-L-alanine amidase-like0Direct
Cdc48 N-terminal domain-like0Direct
Spermadhesin, CUB domain0Direct
L30e/L7ae ribosomal proteins0Direct
Pyrrolidone carboxyl peptidase (pyroglutamate aminopeptidase)0Direct
GroEL chaperone, ATPase domain0Direct
Nuclease0Direct
LexA repressor, N-terminal DNA-binding domain0Direct
3-methyladenine DNA glycosylase (AAG, ANPG, MPG)0Direct
Bacterial dinuclear zinc exopeptidases0Direct
Oligoxyloglucan reducing end-specific cellobiohydrolase0Direct
RecQ helicase DNA-binding domain-like0Direct
GlpX-like bacterial fructose-1,6-bisphosphatase0Direct
RibA-like0Direct
Peptide deformylase0Direct
Viral proteases0Direct
Ku70 subunit middle domain0Direct
TIP49 domain0Direct
Trehalase-like0Direct
Ku70 subunit N-terminal domain0Direct
Dextranase, catalytic domain0Direct
Putative alpha-L-fucosidase, catalytic domain0Direct
CheD-like0Direct
Putative serine hydrolase Ydr428c0Direct
Calpain large subunit, middle domain (domain III)0Direct
Beta-D-glucan exohydrolase, C-terminal domain0Direct
Serine-carboxyl proteinase, SCP0Direct
Retrovirus capsid protein, N-terminal core domain0Direct
Replication initiation protein E10Direct
NlpC/P600Direct
Blood coagulation inhibitor (disintegrin)0Direct
Renal dipeptidase0Direct
PepX C-terminal domain-like0Direct
Peptidyl-tRNA hydrolase domain0Direct
MMLV matrix protein-like0Direct
EAL domain0Direct
Gingipain R (RgpB), C-terminal domain0Direct
Glyoxalase II (hydroxyacylglutathione hydrolase)0Direct
C-type lysozyme0Direct
2',3'-cyclic nucleotide 3'-phosphodiesterase, catalytic domain0Direct
5' nucleotidase-like0Direct
GW domain0Direct
CDH-like0Direct
DNA helicase RuvA subunit, C-terminal domain0Direct
Enolase-phosphatase E10Direct
Peptidylarginine deiminase Pad4, catalytic C-terminal domain0Direct
Staphylococcal nuclease0Direct
Type I dockerin domain0Direct
Kringle modules0Direct
Arylsulfatase0Direct
Putative isomerase YbhE0Direct
Matrix metalloproteases, catalytic domain0Direct
Retroviral integrase, catalytic domain0Direct
Glycosyl hydrolases family 32 C-terminal domain0Direct
Toprim domain0Direct
MutT-like0Direct
HRDC domain from helicases0Direct
AglA-like glucosidase0Direct
Pectin methylesterase0Direct
TMV-like viral coat proteins0Direct
N-acetylglucosamine-6-phosphate deacetylase, NagA0Direct
Phosphonoacetaldehyde hydrolase-like0Direct
Leukotriene A4 hydrolase C-terminal domain0Direct
mRNA decapping enzyme DcpS N-terminal domain0Direct
Nucleoside hydrolase0Direct
Exodeoxyribonuclease V beta chain (RecC), C-terminal domain0Direct
ABC transporter transmembrane region0Direct
Prolyl oligopeptidase, C-terminal domain0Direct
NSP3A-like0Direct
Parvoviridae-like VP0Direct
Proteasome subunits0Direct
Peptidyl-tRNA hydrolase-like0Direct
NPCBM-like0Direct
Dual specificity phosphatase-like0Direct
TSP-1 type 1 repeat0Direct
LD-carboxypeptidase A N-terminal domain-like0Direct
N-terminal domain of DnaB helicase0Direct
LON domain-like0Direct
Clp protease, ClpP subunit0Direct
Adenain-like0Direct
Urease, gamma-subunit0Direct
Aspartyl dipeptidase PepE0Direct
LexA-related0Direct
Imidazolonepropionase-like0Direct
Carbon-carbon bond hydrolase0Direct
Creatinase/aminopeptidase0Direct
Glycosyl hydrolases family 35 catalytic domain0Direct
ABC-transporter additional domain0Direct
Calcium ATPase, transduction domain A0Direct
Methylesterase CheB, C-terminal domain0Direct
Carboxylesterase/lipase0Direct
DTD-like0Direct
MoCo carrier protein-like0Direct
HtrA-like serine proteases0Direct
Pancreatic carboxypeptidases0Direct
Epoxide hydrolase0Direct
Calcium ATPase, transmembrane domain M0Direct
beta-glycanases0Direct
DNA-binding domain of retroviral integrase0Direct
AN1-like Zinc finger0Direct
SAH/MTA deaminase-like0Direct
Lysophospholipase0Direct
Composite domain of glycosyl hydrolase families 5, 30, 39 and 510Direct
Shiga toxin, A-chain0Direct
Helicase-like "domain" of reverse gyrase0Direct
Xylanase/endoglucanase 11/120Direct
Nitrilase0Direct
Fungal zinc peptidase0Direct
N-terminal domain of MutM-like DNA repair proteins0Direct
Aminoacid dehydrogenase-like, C-terminal domain0Direct
Holliday junction resolvase RusA0Direct
Purple acid phosphatase, N-terminal domain0Direct
Carbohydrate binding domain0Direct
Chitinase insertion domain0Direct
Dienelactone hydrolase0Direct
G-type lysozyme0Direct
SurE-like0Direct
Carbamilase0Direct
Integrin alpha N-terminal domain0Direct
SGL-like0Direct
Acyl-CoA thioesterase0Direct
C-terminal domain of PLC-beta0Direct
Acyl-ACP thioesterase-like0Direct
DEATH effector domain, DED0Direct
Ppx/GppA phosphatase0Direct
Dextranase, N-terminal domain0Direct
Clostridium neurotoxins, C-terminal domain0Direct
Viral leader polypeptide zinc finger0Direct
mRNA decapping enzyme DcpS C-terminal domain0Direct
PDEase0Direct
Glycosyl hydrolase family 7 catalytic core0Direct
Ubiquitin carboxyl-terminal hydrolase, UCH0Direct
Carboxypeptidase T0Direct
Ku80 subunit middle domain0Direct
NagD-like0Direct
Retroviral protease (retropepsin)0Direct
Magnesium-dependent phosphatase-1, Mdp10Direct
Elongation factors0Direct
Penicillin binding protein dimerisation domain0Direct
Inosicase0Direct
AbfB domain0Direct
Glycerophosphoryl diester phosphodiesterase0Direct
Metal cation-transporting ATPase, ATP-binding domain N0Direct
Hyaluronidase N-terminal domain-like0Direct
Helicase DNA-binding domain0Direct
Prolyl oligopeptidase, N-terminal domain0Direct
Trehalose-phosphatase0Direct
Trefoil0Direct
HMA, heavy metal-associated domain0Direct
5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain0Direct
Dipeptidyl peptidase I (cathepsin C), exclusion domain0Direct
Esterase domain of haemagglutinin-esterase-fusion glycoprotein HEF10Direct
Carboxylesterase0Direct
Type 2 phosphatidic acid phosphatase, PAP20Direct
Histidine acid phosphatase0Direct
Rhomboid-like0Direct
MMP N-terminal domain0Direct
Putative glucosidase YicI, domain 30Direct
Viral glycoprotein, central and dimerisation domains0Direct
Hypothetical esterase YJL068C0Direct
Janus/Ocnus0Direct
Picornaviridae-like VP (VP1, VP2, VP3 and VP4)0Direct
YlbA-like0Direct
Glutaminase/Asparaginase0Direct
SARS Nsp1-like0Direct
DPP6 catalytic domain-like0Direct
RNase Z-like0Direct
Eng V-like0Direct
Phospholipase C0Direct
Cap-Gly domain0Direct
Glycosyl Hydrolase Family 880Direct
Formate/glycerate dehydrogenases, NAD-domain0Direct
Ppx associated domain0Direct
CheY-related0Direct
GUCT domain0Direct
Complement control module/SCR domain0Direct
Rap30/74 interaction domains0Direct
Porphyromonas-type peptidylarginine deiminase0Direct
Rpp14/Pop5-like0Direct
MtnX-like0Direct
PKD domain0Direct
Zn metallo-beta-lactamase0Direct
Coronavirus NSP8-like0Direct
Penicillin acylase, catalytic domain0Direct
FolH catalytic domain-like0Direct
Extended PAW domain0Direct
GroEL-like chaperone, apical domain0Direct
Invasin/intimin cell-adhesion fragments0Direct
Serine carboxypeptidase-like0Direct
Arginase-like amidino hydrolases0Direct
alpha-L-arabinanase-like0Direct
Nodaviridae-like VP0Direct
RNase P subunit p300Direct
RecA protein-like (ATPase-domain)0Direct
Double-stranded RNA-binding domain (dsRBD)0Direct
Tail specific protease, catalytic domain0Direct
Subtilases0Direct
Hyaluronidase post-catalytic domain-like0Direct
Integrin A (or I) domain0Direct
Nsp15 C-terminal domain-like0Direct
Peptidylarginine deiminase Pad4, middle domain0Direct
Ribonuclease Rh-like0Direct
Glucoamylase0Direct
CinA-like0Direct
alpha-mannosidase, C-terminal domain0Direct
Succinylarginine dihydrolase-like0Direct
Proprotein convertase P-domain0Direct
Bacterial ribonucleases0Direct
CRAL/TRIO N-terminal domain0Direct
Arginine deiminase0Direct
Clostridium neurotoxins, catalytic domain0Direct
RNase III catalytic domain-like0Direct
Sphingomyelin phosphodiesterase-like0Direct
Tetrahydrofolate dehydrogenase/cyclohydrolase0Direct
R3H domain0Direct
Urease, beta-subunit0Direct
beta-N-acetylhexosaminidase domain0Direct
Herpes virus serine proteinase, assemblin0Direct
DNA replication initiator (cdc21/cdc54) N-terminal domain0Direct
Influenza hemagglutinin (stalk)0Direct
Fungal lipases0Direct
Soluble domain of poliovirus core protein 3a0Direct
Germination protease0Direct
Dac-like0Direct
Serralysin-like metalloprotease, catalytic (N-terminal) domain0Direct
YihX-like0Direct
Achaeal helicase C-terminal domain0Direct
Beta-galactosidase LacA, domain 30Direct
N-terminal Zn binding domain of HIV integrase0Direct
CobE/GbiG C-terminal domain-like0Direct
Transferrin receptor-like dimerisation domain0Direct
Virulence effector SptP domain0Direct
Creatininase0Direct
Gamma-glutamyltranspeptidase-like0Direct
Transthyretin (synonym: prealbumin)0Direct
HisE-like (PRA-PH)0Direct
Papain-like0Direct
BRK domain-like0Direct
Exodeoxyribonuclease V beta chain (RecB), C-terminal domain0Direct
Phosphotriesterase-like0Direct
Hydantoinase (dihydropyrimidinase), catalytic domain0Direct
Higher-molecular-weight phosphotyrosine protein phosphatases0Direct
NagB-like0Direct
beta-N-acetylhexosaminidase catalytic domain0Direct
mRNA triphosphatase CET10Direct
D-aminopeptidase, middle and C-terminal domains0Direct
tRNA splicing product Appr>p cyclic nucleotide phosphodiesterase0Direct
NodB-like polysaccharide deacetylase0Direct
Deoxycytidylate deaminase-like0Direct
Cytosine deaminase catalytic domain0Direct
beta-Phosphoglucomutase-like0Direct
Sortase0Direct
Leukotriene A4 hydrolase catalytic domain0Direct
Hjc-like0Direct
RuvC resolvase0Direct
Nsp15 N-terminal domain-like0Direct
Cellulose-binding domain family III0Direct
HisI-like0Direct
Thermolysin-like0Direct
GTP cyclohydrolase I0Direct
Endonuclease I0Direct
RNA helicase0Direct
Subtilase propeptides/inhibitors0Direct
alpha-D-glucuronidase, N-terminal domain0Direct
alpha-Amylases, C-terminal beta-sheet domain0Direct
XseB-like0Direct
Phosphoserine phosphatase0Direct
AstE/AspA-like0Direct
N-terminal domain of RNase HI0Direct
Prohormone convertase 1 pro-domain0Direct
Proline iminopeptidase-like0Direct
Family 17 carbohydrate binding module, CBM170Direct
Clostridium neurotoxins, "coiled-coil" domain0Direct
AF0625-like0Direct
alpha-mannosidase, domain 20Direct
ComB-like0Direct
Retrovirus zinc finger-like domains0Direct
mRNA decapping enzyme-like0Direct
Leukotriene A4 hydrolase N-terminal domain0Direct
Protein serine/threonine phosphatase 2C, C-terminal domain0Direct
Pyrimidine 5'-nucleotidase (UMPH-1)0Direct
Family 9 carbohydrate-binding module, CBD90Direct
Cellulases catalytic domain0Direct
A4 beta-galactosidase middle domain0Direct
Pepsin-like0Direct
MgsA/YrvN C-terminal domain-like0Direct
Allantoicase repeat0Direct
ATP-dependent protease Lon (La), catalytic domain0Direct
alpha-D-glucuronidase/Hyaluronidase catalytic domain0Direct
Outer membrane phospholipase A (OMPLA)0Direct
Chitosanase0Direct
MPP-like0Direct
Archaeal IMP cyclohydrolase PurO0Direct
Z-DNA binding domain0Direct
YicI N-terminal domain-like0Direct
Inositol polyphosphate 5-phosphatase (IPP5)0Direct
CBM4/90Direct
Bee venom hyaluronidase0Direct
Hemopexin-like domain0Direct
Mason-Pfizer monkey virus matrix protein0Direct
Ubiquitin thiolesterase protein OTUB2 (Otubain-2)0Direct
4HBT-like0Direct
UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase LpxC0Direct
CBM110Direct
ADP ribosyl cyclase-like0Direct
PAZ domain0Direct
Astacin0Direct
GAG polyprotein M-domain0Direct
Mismatch glycosylase0Direct
EF-G/eEF-2 domains III and V0Direct
N-acetylmuramoyl-L-alanine amidase-like0Direct
Acetamidase/Formamidase-like0Direct
G proteins0Direct
Sulfolobus fructose-1,6-bisphosphatase-like0Direct
Neutral endopeptidase (neprilysin)0Direct
Hepsin, N-terminal domain0Direct
Bacterial chitobiase, n-terminal domain0Direct
LmbE-like0Direct
Retrovirus capsid protein C-terminal domain0Direct
Cdc48 domain 2-like0Direct
Biotin biosynthesis protein BioH0Direct
mRNA cap methylase0Direct
Dihydroorotase0Direct
CbiG N-terminal domain-like0Direct
FMDV leader protease0Direct
Hydantoinase (dihydropyrimidinase)0Direct
TNF-alpha converting enzyme, TACE, catalytic domain0Direct
Bacterial exopeptidase dimerisation domain0Direct
Serum paraoxonase/arylesterase 1, PON10Direct
RNA-dependent RNA-polymerase0Direct
Dcp2 box A domain0Direct
P1 nuclease0Direct
Patatin0Direct
Sialidases (neuraminidases)0Direct
C-terminal, Zn-finger domain of MutM-like DNA repair proteins0Direct
Ribonuclease A-like0Direct
Apyrase0Direct
Ku80 subunit N-terminal domain0Direct
Alpha-L-arabinofuranosidase B, N-terminal domain0Direct
Clostridium neurotoxins, the second last domain0Direct
GRAM domain0Direct
Protein serine/threonine phosphatase0Direct
TAP-like0Direct
Class B acid phosphatase, AphA0Direct
Inorganic pyrophosphatase0Direct
CBM220Direct
RNase D C-terminal domains0Direct
ITPase (Ham1)0Direct
SAH/MTA deaminase-like0Direct
Beta-galactosidase LacA, domains 4 and 50Direct
Isochorismatase-like hydrolases0Direct
C-terminal domain of Ku800Direct
XPF/Rad1/Mus81 nuclease0Direct
GLA-domain0Direct
DPP6 N-terminal domain-like0Direct
Family 19 glycosidase0Direct
Meta-cation ATPase, catalytic domain P0Direct
beta-Lactamase/D-ala carboxypeptidase0Direct
ABC transporter ATPase domain-like0Direct
Plant invertase/pectin methylesterase inhibitor0Direct
NTF2-like0Direct
Family 28 carbohydrate binding module, CBM280Direct
Cell cycle control phosphatase, catalytic domain0Direct
Creatinase/prolidase N-terminal domain0Direct
Coronavirus NSP10-like0Direct
Immunodeficiency virus matrix proteins0Direct
Caspase catalytic domain0Direct
RNase P subunit p29-like0Direct
beta-Galactosidase, domain 50Direct
Beta-galactosidase LacA, domain 20Direct
Flavivirus capsid protein C0Direct
HTLV-II matrix protein0Direct
Acylphosphatase-like0Direct
Type 1 signal peptidase0Direct
alpha-mannosidase0Direct
Macro domain0Direct
Vertebrate phospholipase A20Direct
PUD-like0Direct
(Glycosyl)asparaginase0Direct
alpha-Subunit of urease0Direct
beta-Galactosidase/glucuronidase, N-terminal domain0Direct
Pancreatic lipase, N-terminal domain0Direct
Cellulose-binding domain0Direct
Staphopain B, prodomain0Direct
Outer membrane protease OMPT0Direct
DNA helicase RuvA subunit, middle domain0Direct
Methenyltetrahydromethanopterin cyclohydrolase0Direct
Pancreatic carboxypeptidase, activation domain0Direct
Type X cellulose binding domain, CBDX0Direct
Ribonuclease H0Direct
Peptidyl-tRNA hydrolase II0Direct
Imidazolonepropionase-like0Direct
LD-carboxypeptidase A C-terminal domain-like0Direct
Penicillin V acylase0Direct
PA1517-like0Direct
Myotubularin-like phosphatases0Direct
Galacturonase0Direct
Leucine aminopeptidase, C-terminal domain0Direct
Cutinase-like0Direct
Putative cyclase0Direct
5'-nucleotidase (syn. UDP-sugar hydrolase), N-terminal domain0Direct
Bacterial GAP domain0Direct
Uracil-DNA glycosylase0Direct
EGF-type module1.839e-16Direct
cAMP-binding domain3.66e-16Direct
PA domain0.00000000000000145Direct
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, phosphatase domain0.000000000000003602Direct
Haloalkane dehalogenase0.00000000000000628Direct
HD domain0.0000000000000178Direct
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, kinase domain0.00000000000002661Direct
MAM domain0.00000000000002819Direct
DJ-1/PfpI0.000000000001369Direct
EF-hand modules in multidomain proteins0.000000000002165Direct
Nitrous oxide reductase, N-terminal domain0.00000000002521Direct
Caspase recruitment domain, CARD0.0000000001425Direct
Tudor domain0.0000000004006Direct
GAF domain0.000000000439Direct
Purine and uridine phosphorylases0.0000000005026Direct
HIT (HINT, histidine triad) family of protein kinase-interacting proteins0.0000000009858Direct
Low-molecular-weight phosphotyrosine protein phosphatases0.000000001622Direct
YjgF/L-PSP0.00000007131Direct
3,4-dihydroxy-2-butanone 4-phosphate synthase, DHBP synthase, RibB0.0000001773Direct
LDL receptor-like module0.000000197Direct
Chromo domain0.0000002362Direct
CYTH domain0.0000002782Direct
TENA/THI-40.0000002885Direct
HCP-like0.0000003854Direct
Peptidoglycan hydrolase LytM0.000001708Direct
Acetylhydrolase0.000001708Direct
Starch-binding domain0.000002232Direct
Ubiquitin-related0.000006466Direct
PUG domain0.00001328Direct
Serralysin-like metalloprotease, C-terminal domain0.00001495Direct
Fibronectin type III0.00001554Direct
phosphatase domain of polynucleotide kinase0.00003334Direct
Glycosyl hydrolases family 160.0000397Direct
UBA domain0.00006174Direct
MIT domain0.00008835Direct
MATH domain0.0001076Direct
PH0987 C-terminal domain-like0.0001479Direct
MYND zinc finger0.0002102Direct
Family 6 carbohydrate binding module, CBM60.0002102Direct
Pleckstrin-homology domain (PH domain)0.0003926Direct
PaaI/YdiI-like0.0006535Direct
PH0987 N-terminal domain-like0.0006535Direct
4-alpha-glucanotransferase, N-terminal domain0.0008179Direct
DEK C-terminal domain0.0008179Direct
Acyl-carrier protein (ACP)0.0008179Direct
Transglutaminase core0.0008453Direct
RibD C-terminal domain-like0.0008974Direct
Third domain of FERM0.001258Inherited
Intein (protein splicing domain)0.001336Inherited
E-set domains of sugar-utilizing enzymes0.001828Inherited
BCR-homology GTPase activation domain (BH-domain)0.002611Inherited
DNase I-like0.002755Inherited
GS domain0.002891Inherited
Cell wall binding repeat0.003008Inherited
4-alpha-glucanotransferase, domain 20.003128Inherited
4-alpha-glucanotransferase, C-terminal domain0.003128Inherited
Galactose-binding domain0.003128Inherited
Ras GEF0.003128Inherited
SAP domain0.004539Inherited
Ricin B-like0.004677Inherited
DNA repair glycosylase, 2 C-terminal domains0.00562Inherited
First domain of FERM0.006846Inherited
Probable phosphatase YrbI0.009655Inherited
F-box domain0.0117Inherited
FAH0.01679Inherited
Intein endonuclease0.02857Inherited
Hydroxynitrile lyase-like0.02857Inherited
Chaperone J-domain0.02857Inherited
Glycosyltransferase family 36 C-terminal domain0.02943Inherited
Haloperoxidase0.03481Inherited
Thioesterase domain of polypeptide, polyketide and fatty acid synthases0.03583Inherited
Leucine rich effector protein YopM0.03644Inherited
Second domain of FERM0.04598Inherited
DnaQ-like 3'-5' exonuclease0.04802Inherited
MaoC-like0.05733Inherited
PX domain0.05733Inherited
UDP-N-acetylglucosamine 2-epimerase0.1061Inherited
PDZ domain0.1322Inherited
DNA repair glycosylase, N-terminal domain0.1328Inherited
Ran binding protein zinc finger-like0.1402Inherited
Canonical RBD0.1603Inherited
PHP domain0.1676Inherited
FHA domain0.1794Inherited
PP1699/LP2961-like0.2036Inherited
mRNA capping enzyme0.2036Inherited
FYVE, a phosphatidylinositol-3-phosphate binding domain0.2264Inherited
Scavenger receptor cysteine-rich (SRCR) domain0.2583Inherited
AlkB-like0.2625Inherited
RelA/SpoT domain0.2865Inherited
CoA transferase alpha subunit-like0.3888Inherited
Ecto-ART0.4611Inherited
PBP transglycosylase domain-like0.5374Inherited
Ankyrin repeat0.6227Inherited
Class I glutamine amidotransferases (GAT)0.7924Inherited
Pyruvate oxidase and decarboxylase, middle domain0.816Inherited
I set domains0.913Inherited
Prokaryotic type I DNA topoisomerase0.9338Inherited
a tRNA synthase domain0.9346Inherited
FabD-like0.9493Inherited
mRNA cap (Guanine N-7) methyltransferase0.9671Inherited
Ras-binding domain, RBD0.9764Inherited
Bromodomain0.9859Inherited
AraD-like aldolase/epimerase1Inherited
Probable ACP-binding domain of malonyl-CoA ACP transacylase1Inherited
beta-carbonic anhydrase, cab1Inherited
Pyruvate oxidase and decarboxylase Pyr module1Inherited
Thiolase-related1Inherited
Formyltransferase1Inherited
Carbamoyl phosphate synthetase, small subunit N-terminal domain1Inherited
CBS-domain pair1Inherited
Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain1Inherited
BC N-terminal domain-like1Inherited
Carbamoyl phosphate synthetase, large subunit connection domain1Inherited
SPRY domain1Inherited
Nitrogenase iron protein-like1Inherited
Alcohol dehydrogenase-like, C-terminal domain1Inherited
Glucose 6-phosphate dehydrogenase-like1Inherited
Cystathionine synthase-like1Inherited
Tetratricopeptide repeat (TPR)1Inherited
Nucleotide and nucleoside kinases1Inherited
Amidase signature (AS) enzymes1Inherited
Phosphate binding protein-like1Inherited
Methylated DNA-protein cysteine methyltransferase, C-terminal domain1Inherited
PHD domain1Inherited
5' to 3' exonuclease catalytic domain1Inherited
BC ATP-binding domain-like1Inherited
WD40-repeat1Inherited
LDH N-terminal domain-like1Inherited
Glutathione peroxidase-like1Inherited
Alcohol dehydrogenase-like, N-terminal domain1Inherited
Terpenoid cyclase C-terminal domain1Inherited
L-histidinol dehydrogenase HisD1Inherited
Cold shock DNA-binding domain-like1Inherited
Trehalose-6-phosphate synthase, OtsA1Inherited
Cofactor-dependent phosphoglycerate mutase1Inherited
ROK1Inherited
Carbonic anhydrase1Inherited
Growth factor receptor domain1Inherited
Class II glutamine amidotransferases1Inherited
Imidazole glycerol phosphate dehydratase1Inherited
Pyruvate oxidase and decarboxylase PP module1Inherited
CCCH zinc finger1Inherited
DNA polymerase I1Inherited
GGDEF domain1Inherited
SH3-domain1Inherited
Tyrosine-dependent oxidoreductases1Inherited
SH2 domain1Inherited
Aspartate/ornithine carbamoyltransferase1Inherited
Tryptophan synthase beta subunit-like PLP-dependent enzymes1Inherited
HpcH/HpaI aldolase1Inherited
WW domain1Inherited
Terpenoid cyclase N-terminal domain1Inherited
SAM (sterile alpha motif) domain1Inherited
Crotonase-like1Inherited
Anticodon-binding domain of Class II aaRS1Inherited


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Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Heat shock protein 70kD (HSP70), C-terminal subdomain0Direct
HAD-like0Direct
Creatininase0Direct
mRNA decapping enzyme DcpS N-terminal domain0Direct
TMV-like viral coat proteins0Direct
Pectin lyase-like0Direct
Autotransporter0Direct
Somatomedin B domain0Direct
Subtilisin-like0Direct
Coronavirus NSP10-like0Direct
Sialidases0Direct
FabD/lysophospholipase-like0Direct
TSP-1 type 1 repeat0Direct
DPP6 N-terminal domain-like0Direct
Coronavirus NSP8-like0Direct
alpha/beta-Hydrolases0Direct
Plant invertase/pectin methylesterase inhibitor0Direct
ssDNA viruses0Direct
Pyrrolidone carboxyl peptidase (pyroglutamate aminopeptidase)0Direct
AN1-like Zinc finger0Direct
Phage fibre proteins0Direct
Retrovirus zinc finger-like domains0Direct
ITPase-like0Direct
Thermostable phytase (3-phytase)0Direct
Microbial ribonucleases0Direct
Fumarylacetoacetate hydrolase, FAH, N-terminal domain0Direct
Putative cyclase0Direct
Blood coagulation inhibitor (disintegrin)0Direct
Creatinase/aminopeptidase0Direct
Origin of replication-binding domain, RBD-like0Direct
Beta-galactosidase LacA, domain 30Direct
Retrovirus capsid protein, N-terminal core domain0Direct
DTD-like0Direct
Restriction endonuclease-like0Direct
Calcium ATPase, transmembrane domain M0Direct
Protease propeptides/inhibitors0Direct
Outer membrane phospholipase A (OMPLA)0Direct
Complement control module/SCR domain0Direct
Glycoside hydrolase/deacetylase0Direct
AbfB domain0Direct
Peptide deformylase0Direct
C-terminal domain of PLC-beta0Direct
beta-Galactosidase/glucuronidase domain0Direct
CheY-like0Direct
Calcium ATPase, transduction domain A0Direct
Concanavalin A-like lectins/glucanases0Direct
DNA primase core0Direct
Glutaminase/Asparaginase0Direct
Rof/RNase P subunit-like0Direct
EF-G C-terminal domain-like0Direct
Influenza hemagglutinin (stalk)0Direct
Cdc48 domain 2-like0Direct
Tetrahydrobiopterin biosynthesis enzymes-like0Direct
Bacterial GAP domain0Direct
D-aminopeptidase, middle and C-terminal domains0Direct
Chitinase insertion domain0Direct
LD-carboxypeptidase A C-terminal domain-like0Direct
Hemopexin-like domain0Direct
Viral leader polypeptide zinc finger0Direct
Seven-hairpin glycosidases0Direct
N-terminal Zn binding domain of HIV integrase0Direct
Glycosyl hydrolase domain0Direct
Invertebrate chitin-binding proteins0Direct
S13-like H2TH domain0Direct
EGF/Laminin0Direct
C2 domain (Calcium/lipid-binding domain, CaLB)0Direct
ComB-like0Direct
Metallo-hydrolase/oxidoreductase0Direct
SEA domain0Direct
MCP/YpsA-like0Direct
Ribosome inactivating proteins (RIP)0Direct
Peptidase/esterase 'gauge' domain0Direct
Macro domain-like0Direct
Positive stranded ssRNA viruses0Direct
(Phosphotyrosine protein) phosphatases II0Direct
N-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
OMPT-like0Direct
HisI-like0Direct
SGNH hydrolase0Direct
Ribonuclease H-like0Direct
5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain0Direct
CYTH-like phosphatases0Direct
Spermadhesin, CUB domain0Direct
Holliday junction resolvase RusA0Direct
Penicillin-binding protein associated domain0Direct
Dcp2 domain-like0Direct
ClpP/crotonase0Direct
JAB1/MPN domain0Direct
Dextranase, N-terminal domain0Direct
Hedgehog/DD-peptidase0Direct
Metal cation-transporting ATPase, ATP-binding domain N0Direct
LmbE-like0Direct
STI-like0Direct
HIT-like0Direct
Nitrous oxide reductase, N-terminal domain0Direct
Dipeptidyl peptidase I (cathepsin C), exclusion domain0Direct
Phospholipase A2, PLA20Direct
Carboxypeptidase regulatory domain-like0Direct
His-Me finger endonucleases0Direct
Inorganic pyrophosphatase0Direct
PGBD-like0Direct
Bacterial exopeptidase dimerisation domain0Direct
Aminopeptidase/glucanase lid domain0Direct
Apyrase0Direct
Carbohydrate-binding domain0Direct
Isochorismatase-like hydrolases0Direct
AlbA-like0Direct
GLA-domain0Direct
Galactose-binding domain-like0Direct
Six-hairpin glycosidases0Direct
Flavivirus capsid protein C0Direct
N-terminal domain of MutM-like DNA repair proteins0Direct
Phospholipase C/P1 nuclease0Direct
Zn-dependent exopeptidases0Direct
Sortase0Direct
X-Prolyl dipeptidyl aminopeptidase PepX, N-terminal domain0Direct
Beta-D-glucan exohydrolase, C-terminal domain0Direct
Trypsin-like serine proteases0Direct
Clostridium neurotoxins, "coiled-coil" domain0Direct
Urease, beta-subunit0Direct
Leukotriene A4 hydrolase N-terminal domain0Direct
N-terminal nucleophile aminohydrolases (Ntn hydrolases)0Direct
Caspase-like0Direct
LexA/Signal peptidase0Direct
Families 57/38 glycoside transferase middle domain0Direct
LigT-like0Direct
Metallo-dependent phosphatases0Direct
N-terminal domain of DnaB helicase0Direct
Urease, gamma-subunit0Direct
dUTPase-like0Direct
Metalloproteases ("zincins"), catalytic domain0Direct
DNA helicase RuvA subunit, C-terminal domain0Direct
N-acetylmuramoyl-L-alanine amidase-like0Direct
Cystatin/monellin0Direct
Retroviral matrix proteins0Direct
Methylesterase CheB, C-terminal domain0Direct
DUSP-like0Direct
Acetamidase/Formamidase-like0Direct
Metallo-dependent hydrolases0Direct
Type I dockerin domain0Direct
SurE-like0Direct
Glycosyl hydrolases family 6, cellulases0Direct
RNase III domain-like0Direct
AF0625-like0Direct
Lysozyme-like0Direct
Carbohydrate phosphatase0Direct
Peptidyl-tRNA hydrolase-like0Direct
Acid proteases0Direct
Cellulose docking domain, dockering0Direct
Cysteine proteinases0Direct
SPOC domain-like0Direct
Ribonuclease Rh-like0Direct
NSP3A-like0Direct
(Trans)glycosidases0Direct
Peptidyl-tRNA hydrolase II0Direct
Formate/glycerate dehydrogenase catalytic domain-like0Direct
DHH phosphoesterases0Direct
RNase A-like0Direct
HMA, heavy metal-associated domain0Direct
C-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
Coronavirus NSP7-like0Direct
Calpain large subunit, middle domain (domain III)0Direct
Putative isomerase YbhE0Direct
Cytidine deaminase-like0Direct
Acid phosphatase/Vanadium-dependent haloperoxidase0Direct
Viral glycoprotein, central and dimerisation domains0Direct
Type X cellulose binding domain, CBDX0Direct
PLC-like phosphodiesterases0Direct
Voltage-gated potassium channels0Direct
RibA-like0Direct
Hyaluronidase post-catalytic domain-like0Direct
SpoIIaa-like0Direct
Carbohydrate binding domain0Direct
Sec-C motif0Direct
GroEL equatorial domain-like0Direct
SARS Nsp1-like0Direct
Glucocorticoid receptor-like (DNA-binding domain)0Direct
beta-N-acetylhexosaminidase-like domain0Direct
BRK domain-like0Direct
Cellulose-binding domain0Direct
Toprim domain0Direct
beta-lactamase/transpeptidase-like0Direct
P-loop containing nucleoside triphosphate hydrolases0Direct
Nudix0Direct
Soluble domain of poliovirus core protein 3a0Direct
Nucleoside hydrolase0Direct
MOP-like0Direct
Arginase/deacetylase0Direct
Rhomboid-like0Direct
Rap30/74 interaction domains0Direct
ABC transporter transmembrane region0Direct
Penicillin binding protein dimerisation domain0Direct
cAMP-binding domain-like0Direct
Methenyltetrahydromethanopterin cyclohydrolase0Direct
XseB-like0Direct
Uracil-DNA glycosylase-like0Direct
Invasin/intimin cell-adhesion fragments0Direct
Arabinanase/levansucrase/invertase0Direct
PP2C-like0Direct
RuvA domain 2-like0Direct
Methylglyoxal synthase-like0Direct
Galactose mutarotase-like0Direct
Herpes virus serine proteinase, assemblin0Direct
ADP-ribosylglycohydrolase0Direct
Transthyretin (synonym: prealbumin)0Direct
Oligoxyloglucan reducing end-specific cellobiohydrolase0Direct
Sec63 N-terminal domain-like0Direct
Peptidylarginine deiminase Pad4, middle domain0Direct
dsRNA-binding domain-like0Direct
L9 N-domain-like0Direct
Viral protein domain0Direct
Sulfolobus fructose-1,6-bisphosphatase-like0Direct
CobE/GbiG C-terminal domain-like0Direct
PKD domain0Direct
Collagen-binding domain0Direct
Purple acid phosphatase, N-terminal domain0Direct
Protein serine/threonine phosphatase 2C, C-terminal domain0Direct
DNase I-like0Direct
CbiG N-terminal domain-like0Direct
CRAL/TRIO N-terminal domain0Direct
Anthrax protective antigen0Direct
R3H domain0Direct
CNF1/YfiH-like putative cysteine hydrolases0Direct
Prokaryotic SH3-related domain0Direct
HRDC-like0Direct
Composite domain of metallo-dependent hydrolases0Direct
Saposin0Direct
Kringle-like0Direct
C-terminal domain of Ku800Direct
Creatinase/prolidase N-terminal domain0Direct
Kazal-type serine protease inhibitors0Direct
HybD-like0Direct
Heat shock protein 70kD (HSP70), peptide-binding domain0Direct
Trefoil0Direct
Carbon-nitrogen hydrolase0Direct
Acylphosphatase/BLUF domain-like0Direct
Aminoacid dehydrogenase-like, N-terminal domain0Direct
CinA-like0Direct
Retrovirus capsid dimerization domain-like0Direct
Plant lectins/antimicrobial peptides0Direct
PDZ domain-like0Direct
all-alpha NTP pyrophosphatases0Direct
EndoU-like0Direct
Peptidyl-tRNA hydrolase domain-like0Direct
Transferrin receptor-like dimerisation domain0Direct
PAZ domain0Direct
LysM domain0Direct
Replicase NSP90Direct
Rnp2-like0Direct
"Winged helix" DNA-binding domain0Direct
Pentein0Direct
Cap-Gly domain0Direct
Archaeal IMP cyclohydrolase PurO0Direct
Initiation factor IF2/eIF5b, domain 30Direct
DNA-binding domain of retroviral integrase0Direct
DNA/RNA polymerases0Direct
Calcium-dependent phosphotriesterase0.0000000000001382Direct
vWA-like0.0000000000001653Direct
Xylose isomerase-like0.0000000000002248Direct
EAL domain-like0.000000000001825Direct
E set domains0.000000000003818Direct
EF-hand0.000000000006359Direct
HD-domain/PDEase-like0.000000000006874Direct
PH domain-like0.0000000000149Direct
Purine and uridine phosphorylases0.0000000001639Direct
Phosphotyrosine protein phosphatases I0.0000000003763Direct
Translation proteins0.000000001229Direct
Staphylococcal nuclease0.000000002113Direct
PA domain0.000000005136Direct
Ubiquitin-like0.00000002555Direct
Tudor/PWWP/MBT0.00000003569Direct
UBA-like0.00000004277Direct
Hairpin loop containing domain-like0.0000001599Direct
LDL receptor-like module0.0000001599Direct
YjgF-like0.0000002465Direct
Hedgehog/intein (Hint) domain0.0000003334Direct
GAF domain-like0.0000003976Direct
DEATH domain0.0000005096Direct
Phospholipase D/nuclease0.000001416Direct
N-(deoxy)ribosyltransferase-like0.000003423Direct
Lipase/lipooxygenase domain (PLAT/LH2 domain)0.000003871Direct
Starch-binding domain-like0.000006462Direct
Fibronectin type III0.000008503Direct
MIT domain0.000008676Direct
Ribosomal protein S5 domain 2-like0.00001087Direct
PUG domain-like0.00001143Direct
beta-Roll0.00001206Direct
CBD9-like0.00002953Direct
DNA clamp0.00002953Direct
HCP-like0.00004488Direct
DEK C-terminal domain0.00004646Direct
PH0987 N-terminal domain-like0.0001332Direct
HIT/MYND zinc finger-like0.0001571Direct
Phosphoglycerate mutase-like0.0002504Direct
FnI-like domain0.000406Direct
Homing endonucleases0.0005066Direct
NagB/RpiA/CoA transferase-like0.0005301Direct
Barwin-like endoglucanases0.0005372Direct
GroEL-intermediate domain like0.0006698Direct
Ricin B-like lectins0.001695Inherited
SRCR-like0.001696Inherited
Chromo domain-like0.001909Inherited
GTPase activation domain, GAP0.002374Inherited
Cell wall binding repeat0.002679Inherited
Ras GEF0.002878Inherited
SAP domain0.003879Inherited
Integrin alpha N-terminal domain0.005728Inherited
WD40 repeat-like0.006711Inherited
F-box domain0.0109Inherited
PX domain0.01263Inherited
FAH0.01397Inherited
GroEL apical domain-like0.02122Inherited
Chaperone J-domain0.02671Inherited
RNA-binding domain, RBD0.03835Inherited
DNA-glycosylase0.04851Inherited
Second domain of FERM0.05019Inherited
C-terminal (heme d1) domain of cytochrome cd1-nitrite reductase0.05116Inherited
Duplicated hybrid motif0.05209Inherited
Rhodanese/Cell cycle control phosphatase0.06287Inherited
TATA-box binding protein-like0.1253Inherited
SMAD/FHA domain0.126Inherited
Class I glutamine amidotransferase-like0.1262Inherited
Ran binding protein zinc finger-like0.1285Inherited
HSP20-like chaperones0.1724Inherited
CRAL/TRIO domain0.173Inherited
PHP domain-like0.178Inherited
beta-sandwich domain of Sec23/240.2435Inherited
YrdC/RibB0.3232Inherited
TRAF domain-like0.3643Inherited
NTF2-like0.3737Inherited
Ankyrin repeat0.6039Inherited
Non-globular alpha+beta subunits of globular proteins0.6215Inherited
post-AAA+ oligomerization domain-like0.6751Inherited
Prokaryotic type I DNA topoisomerase0.8978Inherited
S15/NS1 RNA-binding domain0.9098Inherited
Heme oxygenase-like0.9257Inherited
Kelch motif0.9482Inherited
Bromodomain0.9614Inherited
L30e-like0.9795Inherited
PIN domain-like0.9907Inherited
Methylated DNA-protein cysteine methyltransferase, C-terminal domain1Inherited
Immunoglobulin1Inherited
Inosine monophosphate dehydrogenase (IMPDH)1Inherited
Growth factor receptor domain1Inherited
SH3-domain1Inherited
RmlC-like cupins1Inherited
DNA ligase/mRNA capping enzyme, catalytic domain1Inherited
CCCH zinc finger1Inherited
Carbamoyl phosphate synthetase, large subunit connection domain1Inherited
PUA domain-like1Inherited
ADC-like1Inherited
beta-carbonic anhydrase, cab1Inherited
Nucleic acid-binding proteins1Inherited
Periplasmic binding protein-like II1Inherited
PLP-dependent transferases1Inherited
NAD(P)-binding Rossmann-fold domains1Inherited
GroES-like1Inherited
Class II aaRS ABD-related1Inherited
Bet v1-like1Inherited
PreATP-grasp domain1Inherited
FMT C-terminal domain-like1Inherited
ARM repeat1Inherited
TPR-like1Inherited
Probable ACP-binding domain of malonyl-CoA ACP transacylase1Inherited
Amidase signature (AS) enzymes1Inherited
L domain-like1Inherited
RING/U-box1Inherited
Tryptophan synthase beta subunit-like PLP-dependent enzymes1Inherited
AraD/HMP-PK domain-like1Inherited
Phosphoenolpyruvate/pyruvate domain1Inherited
SAM/Pointed domain1Inherited
FYVE/PHD zinc finger1Inherited
Clavaminate synthase-like1Inherited
Terpenoid synthases1Inherited
Dihydrofolate reductase-like1Inherited
Alkaline phosphatase-like1Inherited
Cupredoxins1Inherited
PYP-like sensor domain (PAS domain)1Inherited
Nucleotide cyclase1Inherited
Carbamoyl phosphate synthetase, small subunit N-terminal domain1Inherited
TGS-like1Inherited
Cyclophilin-like1Inherited
CBS-domain pair1Inherited
Formyltransferase1Inherited
Thioesterase/thiol ester dehydrase-isomerase1Inherited
S-adenosyl-L-methionine-dependent methyltransferases1Inherited
Carbonic anhydrase1Inherited
Quinoprotein alcohol dehydrogenase-like1Inherited
Actin-like ATPase domain1Inherited
Nucleotidyltransferase1Inherited
DHS-like NAD/FAD-binding domain1Inherited
LuxS/MPP-like metallohydrolase1Inherited
Terpenoid cyclases/Protein prenyltransferases1Inherited
LDH C-terminal domain-like1Inherited
WW domain1Inherited
PHP14-like1Inherited
Thiamin diphosphate-binding fold (THDP-binding)1Inherited
SH2 domain1Inherited
Aspartate/ornithine carbamoyltransferase1Inherited
Acyl-CoA N-acyltransferases (Nat)1Inherited
ADP-ribosylation1Inherited
UDP-Glycosyltransferase/glycogen phosphorylase1Inherited
ACP-like1Inherited
Thioredoxin-like1Inherited
ACT-like1Inherited
Thiolase-like1Inherited

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
49899,50386
  • 49899 - Concanavalin A-like lectins/glucanases
  • 50386 - STI-like
  • 0Direct
    52743,49785
  • 52743 - Subtilisin-like
  • 49785 - Galactose-binding domain-like
  • 0Direct
    56672,46919
  • 56672 - DNA/RNA polymerases
  • 46919 - N-terminal Zn binding domain of HIV integrase
  • 0Direct
    49384,51445
  • 49384 - Carbohydrate-binding domain
  • 51445 - (Trans)glycosidases
  • 0Direct
    53098,51283
  • 53098 - Ribonuclease H-like
  • 51283 - dUTPase-like
  • 0Direct
    49854,50494
  • 49854 - Spermadhesin, CUB domain
  • 50494 - Trypsin-like serine proteases
  • 0Direct
    49452,52799
  • 49452 - Starch-binding domain-like
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 0Direct
    53187,47672
  • 53187 - Zn-dependent exopeptidases
  • 47672 - Transferrin receptor-like dimerisation domain
  • 0Direct
    55008,55008
  • 55008 - HMA, heavy metal-associated domain
  • 55008 - HMA, heavy metal-associated domain
  • 0Direct
    54211,54637
  • 54211 - Ribosomal protein S5 domain 2-like
  • 54637 - Thioesterase/thiol ester dehydrase-isomerase
  • 0Direct
    52540,56712
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 56712 - Prokaryotic type I DNA topoisomerase
  • 0Direct
    53756,53067
  • 53756 - UDP-Glycosyltransferase/glycogen phosphorylase
  • 53067 - Actin-like ATPase domain
  • 0Direct
    57492,74650
  • 57492 - Trefoil
  • 74650 - Galactose mutarotase-like
  • 0Direct
    47986,52129
  • 47986 - DEATH domain
  • 52129 - Caspase-like
  • 0Direct
    55021,53328
  • 55021 - ACT-like
  • 53328 - Formyltransferase
  • 0Direct
    51445,49303
  • 51445 - (Trans)glycosidases
  • 49303 - beta-Galactosidase/glucuronidase domain
  • 0Direct
    140586,55811
  • 140586 - Dcp2 domain-like
  • 55811 - Nudix
  • 0Direct
    52499,47336
  • 52499 - Isochorismatase-like hydrolases
  • 47336 - ACP-like
  • 0Direct
    51445,57180
  • 51445 - (Trans)glycosidases
  • 57180 - Cellulose-binding domain
  • 0Direct
    50199,50199
  • 50199 - Staphylococcal nuclease
  • 50199 - Staphylococcal nuclease
  • 0Direct
    57756,51283
  • 57756 - Retrovirus zinc finger-like domains
  • 51283 - dUTPase-like
  • 0Direct
    51011,49265
  • 51011 - Glycosyl hydrolase domain
  • 49265 - Fibronectin type III
  • 0Direct
    52540,54928
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 54928 - RNA-binding domain, RBD
  • 0Direct
    101908,56219
  • 101908 - Putative isomerase YbhE
  • 56219 - DNase I-like
  • 0Direct
    49303,74650
  • 49303 - beta-Galactosidase/glucuronidase domain
  • 74650 - Galactose mutarotase-like
  • 0Direct
    54980,54980
  • 54980 - EF-G C-terminal domain-like
  • 54980 - EF-G C-terminal domain-like
  • 0Direct
    55486,48371
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 48371 - ARM repeat
  • 0Direct
    49899,49785
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49785 - Galactose-binding domain-like
  • 0Direct
    51283,46919
  • 51283 - dUTPase-like
  • 46919 - N-terminal Zn binding domain of HIV integrase
  • 0Direct
    63411,63411
  • 63411 - LuxS/MPP-like metallohydrolase
  • 63411 - LuxS/MPP-like metallohydrolase
  • 0Direct
    57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0Direct
    46785,51306
  • 46785 - "Winged helix" DNA-binding domain
  • 51306 - LexA/Signal peptidase
  • 0Direct
    53300,50494
  • 53300 - vWA-like
  • 50494 - Trypsin-like serine proteases
  • 0Direct
    51445,49384
  • 51445 - (Trans)glycosidases
  • 49384 - Carbohydrate-binding domain
  • 0Direct
    56601,69189
  • 56601 - beta-lactamase/transpeptidase-like
  • 69189 - Penicillin-binding protein associated domain
  • 0Direct
    69065,54768
  • 69065 - RNase III domain-like
  • 54768 - dsRNA-binding domain-like
  • 0Direct
    50729,47473
  • 50729 - PH domain-like
  • 47473 - EF-hand
  • 0Direct
    56300,47473
  • 56300 - Metallo-dependent phosphatases
  • 47473 - EF-hand
  • 0Direct
    52540,57756
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 57756 - Retrovirus zinc finger-like domains
  • 0Direct
    74924,74924
  • 74924 - Cap-Gly domain
  • 74924 - Cap-Gly domain
  • 0Direct
    50249,52540
  • 50249 - Nucleic acid-binding proteins
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    49785,63446
  • 49785 - Galactose-binding domain-like
  • 63446 - Type I dockerin domain
  • 0Direct
    56601,48403
  • 56601 - beta-lactamase/transpeptidase-like
  • 48403 - Ankyrin repeat
  • 0Direct
    141734,101386
  • 141734 - HisI-like
  • 101386 - all-alpha NTP pyrophosphatases
  • 0Direct
    57440,50494
  • 57440 - Kringle-like
  • 50494 - Trypsin-like serine proteases
  • 0Direct
    101148,51126
  • 101148 - Plant invertase/pectin methylesterase inhibitor
  • 51126 - Pectin lyase-like
  • 0Direct
    55464,52540
  • 55464 - Origin of replication-binding domain, RBD-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    53955,54106
  • 53955 - Lysozyme-like
  • 54106 - LysM domain
  • 0Direct
    57414,57440
  • 57414 - Hairpin loop containing domain-like
  • 57440 - Kringle-like
  • 0Direct
    63737,55486
  • 63737 - Leukotriene A4 hydrolase N-terminal domain
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 0Direct
    51126,51126
  • 51126 - Pectin lyase-like
  • 51126 - Pectin lyase-like
  • 0Direct
    55920,46785
  • 55920 - Creatinase/aminopeptidase
  • 46785 - "Winged helix" DNA-binding domain
  • 0Direct
    82895,82895
  • 82895 - TSP-1 type 1 repeat
  • 82895 - TSP-1 type 1 repeat
  • 0Direct
    56983,81296
  • 56983 - Viral glycoprotein, central and dimerisation domains
  • 81296 - E set domains
  • 0Direct
    52540,54631
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 54631 - CBS-domain pair
  • 0Direct
    53223,51735
  • 53223 - Aminoacid dehydrogenase-like, N-terminal domain
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 0Direct
    57850,54001
  • 57850 - RING/U-box
  • 54001 - Cysteine proteinases
  • 0Direct
    56487,57424
  • 56487 - SRCR-like
  • 57424 - LDL receptor-like module
  • 0Direct
    49599,54001
  • 49599 - TRAF domain-like
  • 54001 - Cysteine proteinases
  • 0Direct
    54001,53098
  • 54001 - Cysteine proteinases
  • 53098 - Ribonuclease H-like
  • 0Direct
    49562,52151
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 52151 - FabD/lysophospholipase-like
  • 0Direct
    57424,57424
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 0Direct
    51283,50630
  • 51283 - dUTPase-like
  • 50630 - Acid proteases
  • 0Direct
    52266,103515
  • 52266 - SGNH hydrolase
  • 103515 - Autotransporter
  • 0Direct
    51445,51011
  • 51445 - (Trans)glycosidases
  • 51011 - Glycosyl hydrolase domain
  • 0Direct
    51695,51695
  • 51695 - PLC-like phosphodiesterases
  • 51695 - PLC-like phosphodiesterases
  • 0Direct
    48208,63446
  • 48208 - Six-hairpin glycosidases
  • 63446 - Type I dockerin domain
  • 0Direct
    52821,52799
  • 52821 - Rhodanese/Cell cycle control phosphatase
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 0Direct
    81653,81665
  • 81653 - Calcium ATPase, transduction domain A
  • 81665 - Calcium ATPase, transmembrane domain M
  • 0Direct
    47090,47090
  • 47090 - PGBD-like
  • 47090 - PGBD-like
  • 0Direct
    57603,57440
  • 57603 - FnI-like domain
  • 57440 - Kringle-like
  • 0Direct
    47473,51695
  • 47473 - EF-hand
  • 51695 - PLC-like phosphodiesterases
  • 0Direct
    49265,49452
  • 49265 - Fibronectin type III
  • 49452 - Starch-binding domain-like
  • 0Direct
    55486,58091
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 58091 - Clostridium neurotoxins, "coiled-coil" domain
  • 0Direct
    56784,54211
  • 56784 - HAD-like
  • 54211 - Ribosomal protein S5 domain 2-like
  • 0Direct
    159936,53335
  • 159936 - NSP3A-like
  • 53335 - S-adenosyl-L-methionine-dependent methyltransferases
  • 0Direct
    56672,88633
  • 56672 - DNA/RNA polymerases
  • 88633 - Positive stranded ssRNA viruses
  • 0Direct
    50249,47781
  • 50249 - Nucleic acid-binding proteins
  • 47781 - RuvA domain 2-like
  • 0Direct
    55486,51120
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 51120 - beta-Roll
  • 0Direct
    81624,46946
  • 81624 - N-terminal domain of MutM-like DNA repair proteins
  • 46946 - S13-like H2TH domain
  • 0Direct
    55846,47090
  • 55846 - N-acetylmuramoyl-L-alanine amidase-like
  • 47090 - PGBD-like
  • 0Direct
    51445,140657
  • 51445 - (Trans)glycosidases
  • 140657 - Hyaluronidase post-catalytic domain-like
  • 0Direct
    55486,49899
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0Direct
    49854,57535
  • 49854 - Spermadhesin, CUB domain
  • 57535 - Complement control module/SCR domain
  • 0Direct
    52540,47917
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 47917 - C-terminal domain of alpha and beta subunits of F1 ATP synthase
  • 0Direct
    48150,55811
  • 48150 - DNA-glycosylase
  • 55811 - Nudix
  • 0Direct
    88633,88633
  • 88633 - Positive stranded ssRNA viruses
  • 88633 - Positive stranded ssRNA viruses
  • 0Direct
    57535,57535
  • 57535 - Complement control module/SCR domain
  • 57535 - Complement control module/SCR domain
  • 0Direct
    51278,51338
  • 51278 - Urease, beta-subunit
  • 51338 - Composite domain of metallo-dependent hydrolases
  • 0Direct
    159672,159664
  • 159672 - CbiG N-terminal domain-like
  • 159664 - CobE/GbiG C-terminal domain-like
  • 0Direct
    50993,53474
  • 50993 - Peptidase/esterase 'gauge' domain
  • 53474 - alpha/beta-Hydrolases
  • 0Direct
    52540,47819
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 47819 - HRDC-like
  • 0Direct
    57756,50630
  • 57756 - Retrovirus zinc finger-like domains
  • 50630 - Acid proteases
  • 0Direct
    51556,51338
  • 51556 - Metallo-dependent hydrolases
  • 51338 - Composite domain of metallo-dependent hydrolases
  • 0Direct
    140657,49785
  • 140657 - Hyaluronidase post-catalytic domain-like
  • 49785 - Galactose-binding domain-like
  • 0Direct
    51011,51445
  • 51011 - Glycosyl hydrolase domain
  • 51445 - (Trans)glycosidases
  • 0Direct
    52540,50447
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 50447 - Translation proteins
  • 0Direct
    53774,48403
  • 53774 - Glutaminase/Asparaginase
  • 48403 - Ankyrin repeat
  • 0Direct
    49363,56300
  • 49363 - Purple acid phosphatase, N-terminal domain
  • 56300 - Metallo-dependent phosphatases
  • 0Direct
    55545,51445
  • 55545 - beta-N-acetylhexosaminidase-like domain
  • 51445 - (Trans)glycosidases
  • 0Direct
    53098,46919
  • 53098 - Ribonuclease H-like
  • 46919 - N-terminal Zn binding domain of HIV integrase
  • 0Direct
    48208,49384
  • 48208 - Six-hairpin glycosidases
  • 49384 - Carbohydrate-binding domain
  • 0Direct
    57016,53955
  • 57016 - Plant lectins/antimicrobial peptides
  • 53955 - Lysozyme-like
  • 0Direct
    53092,53092
  • 53092 - Creatinase/prolidase N-terminal domain
  • 53092 - Creatinase/prolidase N-terminal domain
  • 0Direct
    49503,110083
  • 49503 - Cupredoxins
  • 110083 - Peptidylarginine deiminase Pad4, middle domain
  • 0Direct
    140367,143076
  • 140367 - Coronavirus NSP7-like
  • 143076 - Coronavirus NSP8-like
  • 0Direct
    143076,101816
  • 143076 - Coronavirus NSP8-like
  • 101816 - Replicase NSP9
  • 0Direct
    90123,52540
  • 90123 - ABC transporter transmembrane region
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    51338,51556
  • 51338 - Composite domain of metallo-dependent hydrolases
  • 51556 - Metallo-dependent hydrolases
  • 0Direct
    55821,142695
  • 55821 - YrdC/RibB
  • 142695 - RibA-like
  • 0Direct
    57424,56487
  • 57424 - LDL receptor-like module
  • 56487 - SRCR-like
  • 0Direct
    56300,56300
  • 56300 - Metallo-dependent phosphatases
  • 56300 - Metallo-dependent phosphatases
  • 0Direct
    51283,51283
  • 51283 - dUTPase-like
  • 51283 - dUTPase-like
  • 0Direct
    49384,55545
  • 49384 - Carbohydrate-binding domain
  • 55545 - beta-N-acetylhexosaminidase-like domain
  • 0Direct
    52980,47781
  • 52980 - Restriction endonuclease-like
  • 47781 - RuvA domain 2-like
  • 0Direct
    50494,50156
  • 50494 - Trypsin-like serine proteases
  • 50156 - PDZ domain-like
  • 0Direct
    53335,56672
  • 53335 - S-adenosyl-L-methionine-dependent methyltransferases
  • 56672 - DNA/RNA polymerases
  • 0Direct
    52540,54211
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 54211 - Ribosomal protein S5 domain 2-like
  • 0Direct
    53927,53927
  • 53927 - Cytidine deaminase-like
  • 53927 - Cytidine deaminase-like
  • 0Direct
    101596,51126
  • 101596 - Dextranase, N-terminal domain
  • 51126 - Pectin lyase-like
  • 0Direct
    158702,52540
  • 158702 - Sec63 N-terminal domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    53300,100939
  • 53300 - vWA-like
  • 100939 - SPOC domain-like
  • 0Direct
    49854,49854
  • 49854 - Spermadhesin, CUB domain
  • 49854 - Spermadhesin, CUB domain
  • 0Direct
    101690,53098
  • 101690 - PAZ domain
  • 53098 - Ribonuclease H-like
  • 0Direct
    57630,57440
  • 57630 - GLA-domain
  • 57440 - Kringle-like
  • 0Direct
    56487,50494
  • 56487 - SRCR-like
  • 50494 - Trypsin-like serine proteases
  • 0Direct
    49785,51445
  • 49785 - Galactose-binding domain-like
  • 51445 - (Trans)glycosidases
  • 0Direct
    116846,52540
  • 116846 - MIT domain
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    47836,47943
  • 47836 - Retroviral matrix proteins
  • 47943 - Retrovirus capsid protein, N-terminal core domain
  • 0Direct
    53098,54928
  • 53098 - Ribonuclease H-like
  • 54928 - RNA-binding domain, RBD
  • 0Direct
    109715,52799
  • 109715 - DEK C-terminal domain
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 0Direct
    53187,55031
  • 53187 - Zn-dependent exopeptidases
  • 55031 - Bacterial exopeptidase dimerisation domain
  • 0Direct
    50494,52540
  • 50494 - Trypsin-like serine proteases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    49785,49785
  • 49785 - Galactose-binding domain-like
  • 49785 - Galactose-binding domain-like
  • 0Direct
    82671,57424
  • 82671 - SEA domain
  • 57424 - LDL receptor-like module
  • 0Direct
    54001,88633
  • 54001 - Cysteine proteinases
  • 88633 - Positive stranded ssRNA viruses
  • 0Direct
    49899,49384
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49384 - Carbohydrate-binding domain
  • 0Direct
    55608,56712
  • 55608 - Homing endonucleases
  • 56712 - Prokaryotic type I DNA topoisomerase
  • 0Direct
    50249,50249
  • 50249 - Nucleic acid-binding proteins
  • 50249 - Nucleic acid-binding proteins
  • 0Direct
    56784,52540
  • 56784 - HAD-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    55811,55811
  • 55811 - Nudix
  • 55811 - Nudix
  • 0Direct
    48403,52151
  • 48403 - Ankyrin repeat
  • 52151 - FabD/lysophospholipase-like
  • 0Direct
    46938,52087
  • 46938 - CRAL/TRIO N-terminal domain
  • 52087 - CRAL/TRIO domain
  • 0Direct
    51445,49785
  • 51445 - (Trans)glycosidases
  • 49785 - Galactose-binding domain-like
  • 0Direct
    143503,54001
  • 143503 - PUG domain-like
  • 54001 - Cysteine proteinases
  • 0Direct
    52540,89043
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 89043 - Soluble domain of poliovirus core protein 3a
  • 0Direct
    48537,49723
  • 48537 - Phospholipase C/P1 nuclease
  • 49723 - Lipase/lipooxygenase domain (PLAT/LH2 domain)
  • 0Direct
    49303,49303
  • 49303 - beta-Galactosidase/glucuronidase domain
  • 49303 - beta-Galactosidase/glucuronidase domain
  • 0Direct
    50494,56672
  • 50494 - Trypsin-like serine proteases
  • 56672 - DNA/RNA polymerases
  • 0Direct
    49758,47473
  • 49758 - Calpain large subunit, middle domain (domain III)
  • 47473 - EF-hand
  • 0Direct
    49879,54197
  • 49879 - SMAD/FHA domain
  • 54197 - HIT-like
  • 0Direct
    52768,52768
  • 52768 - Arginase/deacetylase
  • 52768 - Arginase/deacetylase
  • 0Direct
    52540,56672
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 56672 - DNA/RNA polymerases
  • 0Direct
    56784,56784
  • 56784 - HAD-like
  • 56784 - HAD-like
  • 0Direct
    49854,49899
  • 49854 - Spermadhesin, CUB domain
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0Direct
    52540,47370
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 47370 - Bromodomain
  • 0Direct
    54897,53187
  • 54897 - Protease propeptides/inhibitors
  • 53187 - Zn-dependent exopeptidases
  • 0Direct
    52540,54980
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 54980 - EF-G C-terminal domain-like
  • 0Direct
    54001,144232
  • 54001 - Cysteine proteinases
  • 144232 - HIT/MYND zinc finger-like
  • 0Direct
    50692,54585
  • 50692 - ADC-like
  • 54585 - Cdc48 domain 2-like
  • 0Direct
    51011,117100
  • 51011 - Glycosyl hydrolase domain
  • 117100 - Beta-galactosidase LacA, domain 3
  • 0Direct
    51445,54556
  • 51445 - (Trans)glycosidases
  • 54556 - Chitinase insertion domain
  • 0Direct
    56219,56219
  • 56219 - DNase I-like
  • 56219 - DNase I-like
  • 0Direct
    54637,55961
  • 54637 - Thioesterase/thiol ester dehydrase-isomerase
  • 55961 - Bet v1-like
  • 0Direct
    51445,81296
  • 51445 - (Trans)glycosidases
  • 81296 - E set domains
  • 0Direct
    55658,53098
  • 55658 - L9 N-domain-like
  • 53098 - Ribonuclease H-like
  • 0Direct
    52129,81296
  • 52129 - Caspase-like
  • 81296 - E set domains
  • 0Direct
    57535,53300
  • 57535 - Complement control module/SCR domain
  • 53300 - vWA-like
  • 0Direct
    81660,56784
  • 81660 - Metal cation-transporting ATPase, ATP-binding domain N
  • 56784 - HAD-like
  • 0Direct
    54236,56784
  • 54236 - Ubiquitin-like
  • 56784 - HAD-like
  • 0Direct
    89260,89260
  • 89260 - Collagen-binding domain
  • 89260 - Collagen-binding domain
  • 0Direct
    54637,52151
  • 54637 - Thioesterase/thiol ester dehydrase-isomerase
  • 52151 - FabD/lysophospholipase-like
  • 0Direct
    47819,47819
  • 47819 - HRDC-like
  • 47819 - HRDC-like
  • 0Direct
    81606,81601
  • 81606 - PP2C-like
  • 81601 - Protein serine/threonine phosphatase 2C, C-terminal domain
  • 0Direct
    53474,53474
  • 53474 - alpha/beta-Hydrolases
  • 53474 - alpha/beta-Hydrolases
  • 0Direct
    51011,50370
  • 51011 - Glycosyl hydrolase domain
  • 50370 - Ricin B-like lectins
  • 0Direct
    49265,49384
  • 49265 - Fibronectin type III
  • 49384 - Carbohydrate-binding domain
  • 0Direct
    88713,88688
  • 88713 - Glycoside hydrolase/deacetylase
  • 88688 - Families 57/38 glycoside transferase middle domain
  • 0Direct
    48592,54849
  • 48592 - GroEL equatorial domain-like
  • 54849 - GroEL-intermediate domain like
  • 0Direct
    56672,52540
  • 56672 - DNA/RNA polymerases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    55550,52799
  • 55550 - SH2 domain
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 0Direct
    52540,48403
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 48403 - Ankyrin repeat
  • 0Direct
    54001,46934
  • 54001 - Cysteine proteinases
  • 46934 - UBA-like
  • 0Direct
    57630,57196
  • 57630 - GLA-domain
  • 57196 - EGF/Laminin
  • 0Direct
    50886,50886
  • 50886 - D-aminopeptidase, middle and C-terminal domains
  • 50886 - D-aminopeptidase, middle and C-terminal domains
  • 0Direct
    49899,110221
  • 49899 - Concanavalin A-like lectins/glucanases
  • 110221 - AbfB domain
  • 0Direct
    52540,142877
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 142877 - EndoU-like
  • 0Direct
    51695,49562
  • 51695 - PLC-like phosphodiesterases
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 0Direct
    52025,53187
  • 52025 - PA domain
  • 53187 - Zn-dependent exopeptidases
  • 0Direct
    160481,160481
  • 160481 - BRK domain-like
  • 160481 - BRK domain-like
  • 0Direct
    54111,51278
  • 54111 - Urease, gamma-subunit
  • 51278 - Urease, beta-subunit
  • 0Direct
    47473,144091
  • 47473 - EF-hand
  • 144091 - Rhomboid-like
  • 0Direct
    52266,49818
  • 52266 - SGNH hydrolase
  • 49818 - Viral protein domain
  • 0Direct
    101386,101386
  • 101386 - all-alpha NTP pyrophosphatases
  • 101386 - all-alpha NTP pyrophosphatases
  • 0Direct
    101386,53720
  • 101386 - all-alpha NTP pyrophosphatases
  • 53720 - ALDH-like
  • 0Direct
    49854,57196
  • 49854 - Spermadhesin, CUB domain
  • 57196 - EGF/Laminin
  • 0Direct
    81665,81660
  • 81665 - Calcium ATPase, transmembrane domain M
  • 81660 - Metal cation-transporting ATPase, ATP-binding domain N
  • 0Direct
    54585,52540
  • 54585 - Cdc48 domain 2-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    57535,50494
  • 57535 - Complement control module/SCR domain
  • 50494 - Trypsin-like serine proteases
  • 0Direct
    52743,52025
  • 52743 - Subtilisin-like
  • 52025 - PA domain
  • 0Direct
    55550,50044
  • 55550 - SH2 domain
  • 50044 - SH3-domain
  • 0Direct
    53098,50122
  • 53098 - Ribonuclease H-like
  • 50122 - DNA-binding domain of retroviral integrase
  • 0Direct
    49899,49599
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49599 - TRAF domain-like
  • 0Direct
    54160,54160
  • 54160 - Chromo domain-like
  • 54160 - Chromo domain-like
  • 0Direct
    50729,56024
  • 50729 - PH domain-like
  • 56024 - Phospholipase D/nuclease
  • 0Direct
    54403,54001
  • 54403 - Cystatin/monellin
  • 54001 - Cysteine proteinases
  • 0Direct
    49562,56024
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 56024 - Phospholipase D/nuclease
  • 0Direct
    52540,52540
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    47986,47986
  • 47986 - DEATH domain
  • 47986 - DEATH domain
  • 0Direct
    51445,51055
  • 51445 - (Trans)glycosidases
  • 51055 - Carbohydrate binding domain
  • 0Direct
    49344,49344
  • 49344 - CBD9-like
  • 49344 - CBD9-like
  • 0Direct
    50916,46785
  • 50916 - Rap30/74 interaction domains
  • 46785 - "Winged helix" DNA-binding domain
  • 0Direct
    46946,57716
  • 46946 - S13-like H2TH domain
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 0Direct
    81665,56784
  • 81665 - Calcium ATPase, transmembrane domain M
  • 56784 - HAD-like
  • 0Direct
    52540,49899
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0Direct
    57424,49854
  • 57424 - LDL receptor-like module
  • 49854 - Spermadhesin, CUB domain
  • 0Direct
    52317,51011
  • 52317 - Class I glutamine amidotransferase-like
  • 51011 - Glycosyl hydrolase domain
  • 0Direct
    53098,47819
  • 53098 - Ribonuclease H-like
  • 47819 - HRDC-like
  • 0Direct
    81296,48208
  • 81296 - E set domains
  • 48208 - Six-hairpin glycosidases
  • 0Direct
    47233,52799
  • 47233 - Bacterial GAP domain
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 0Direct
    53335,52949
  • 53335 - S-adenosyl-L-methionine-dependent methyltransferases
  • 52949 - Macro domain-like
  • 0Direct
    158702,81296
  • 158702 - Sec63 N-terminal domain-like
  • 81296 - E set domains
  • 0Direct
    52058,56219
  • 52058 - L domain-like
  • 56219 - DNase I-like
  • 0Direct
    52151,52151
  • 52151 - FabD/lysophospholipase-like
  • 52151 - FabD/lysophospholipase-like
  • 0Direct
    90188,53649
  • 90188 - Somatomedin B domain
  • 53649 - Alkaline phosphatase-like
  • 0Direct
    53187,49464
  • 53187 - Zn-dependent exopeptidases
  • 49464 - Carboxypeptidase regulatory domain-like
  • 0Direct
    56784,81665
  • 56784 - HAD-like
  • 81665 - Calcium ATPase, transmembrane domain M
  • 0Direct
    49899,48726
  • 49899 - Concanavalin A-like lectins/glucanases
  • 48726 - Immunoglobulin
  • 0Direct
    53067,100920
  • 53067 - Actin-like ATPase domain
  • 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
  • 0Direct
    57196,49854
  • 57196 - EGF/Laminin
  • 49854 - Spermadhesin, CUB domain
  • 0Direct
    57630,57184
  • 57630 - GLA-domain
  • 57184 - Growth factor receptor domain
  • 0Direct
    53474,49785
  • 53474 - alpha/beta-Hydrolases
  • 49785 - Galactose-binding domain-like
  • 0Direct
    54001,143791
  • 54001 - Cysteine proteinases
  • 143791 - DUSP-like
  • 0Direct
    102860,54197
  • 102860 - mRNA decapping enzyme DcpS N-terminal domain
  • 54197 - HIT-like
  • 0Direct
    82708,53098
  • 82708 - R3H domain
  • 53098 - Ribonuclease H-like
  • 0Direct
    52540,50331
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 50331 - MOP-like
  • 0Direct
    52540,52156
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52156 - Initiation factor IF2/eIF5b, domain 3
  • 0Direct
    54106,54001
  • 54106 - LysM domain
  • 54001 - Cysteine proteinases
  • 0Direct
    57196,50494
  • 57196 - EGF/Laminin
  • 50494 - Trypsin-like serine proteases
  • 0Direct
    55781,109604
  • 55781 - GAF domain-like
  • 109604 - HD-domain/PDEase-like
  • 0Direct
    53092,55920
  • 53092 - Creatinase/prolidase N-terminal domain
  • 55920 - Creatinase/aminopeptidase
  • 0Direct
    103642,55920
  • 103642 - Sec-C motif
  • 55920 - Creatinase/aminopeptidase
  • 0Direct
    89043,50494
  • 89043 - Soluble domain of poliovirus core protein 3a
  • 50494 - Trypsin-like serine proteases
  • 0Direct
    100939,101420
  • 100939 - SPOC domain-like
  • 101420 - C-terminal domain of Ku80
  • 0Direct
    54897,52743
  • 54897 - Protease propeptides/inhibitors
  • 52743 - Subtilisin-like
  • 0Direct
    49785,49303
  • 49785 - Galactose-binding domain-like
  • 49303 - beta-Galactosidase/glucuronidase domain
  • 0Direct
    48371,54001
  • 48371 - ARM repeat
  • 54001 - Cysteine proteinases
  • 0Direct
    55154,56091
  • 55154 - CYTH-like phosphatases
  • 56091 - DNA ligase/mRNA capping enzyme, catalytic domain
  • 0Direct
    52799,56091
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 56091 - DNA ligase/mRNA capping enzyme, catalytic domain
  • 0Direct
    49562,54236
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 54236 - Ubiquitin-like
  • 0Direct
    56784,53474
  • 56784 - HAD-like
  • 53474 - alpha/beta-Hydrolases
  • 0Direct
    110296,110296
  • 110296 - Oligoxyloglucan reducing end-specific cellobiohydrolase
  • 110296 - Oligoxyloglucan reducing end-specific cellobiohydrolase
  • 0Direct
    52279,56988
  • 52279 - Beta-D-glucan exohydrolase, C-terminal domain
  • 56988 - Anthrax protective antigen
  • 0Direct
    56601,50886
  • 56601 - beta-lactamase/transpeptidase-like
  • 50886 - D-aminopeptidase, middle and C-terminal domains
  • 0Direct
    54160,52540
  • 54160 - Chromo domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    50044,51695
  • 50044 - SH3-domain
  • 51695 - PLC-like phosphodiesterases
  • 0Direct
    57180,51445
  • 57180 - Cellulose-binding domain
  • 51445 - (Trans)glycosidases
  • 0Direct
    48208,49452
  • 48208 - Six-hairpin glycosidases
  • 49452 - Starch-binding domain-like
  • 0Direct
    54001,49785
  • 54001 - Cysteine proteinases
  • 49785 - Galactose-binding domain-like
  • 0Direct
    55486,57440
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 57440 - Kringle-like
  • 0Direct
    52540,46785
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 46785 - "Winged helix" DNA-binding domain
  • 0Direct
    56300,55816
  • 56300 - Metallo-dependent phosphatases
  • 55816 - 5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain
  • 0Direct
    54236,54001
  • 54236 - Ubiquitin-like
  • 54001 - Cysteine proteinases
  • 0Direct
    69065,69065
  • 69065 - RNase III domain-like
  • 69065 - RNase III domain-like
  • 0Direct
    101821,53187
  • 101821 - Aminopeptidase/glucanase lid domain
  • 53187 - Zn-dependent exopeptidases
  • 0Direct
    50615,52540
  • 50615 - N-terminal domain of alpha and beta subunits of F1 ATP synthase
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    51445,63446
  • 51445 - (Trans)glycosidases
  • 63446 - Type I dockerin domain
  • 0Direct
    101816,144246
  • 101816 - Replicase NSP9
  • 144246 - Coronavirus NSP10-like
  • 0Direct
    57424,50494
  • 57424 - LDL receptor-like module
  • 50494 - Trypsin-like serine proteases
  • 0Direct
    100920,100934
  • 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
  • 100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain
  • 0Direct
    81324,52799
  • 81324 - Voltage-gated potassium channels
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 0Direct
    82671,49854
  • 82671 - SEA domain
  • 49854 - Spermadhesin, CUB domain
  • 0Direct
    75001,54001
  • 75001 - Dipeptidyl peptidase I (cathepsin C), exclusion domain
  • 54001 - Cysteine proteinases
  • 0Direct
    47781,46929
  • 47781 - RuvA domain 2-like
  • 46929 - DNA helicase RuvA subunit, C-terminal domain
  • 0Direct
    88633,50494
  • 88633 - Positive stranded ssRNA viruses
  • 50494 - Trypsin-like serine proteases
  • 0Direct
    56519,56601
  • 56519 - Penicillin binding protein dimerisation domain
  • 56601 - beta-lactamase/transpeptidase-like
  • 0Direct
    54001,49758
  • 54001 - Cysteine proteinases
  • 49758 - Calpain large subunit, middle domain (domain III)
  • 0Direct
    51445,52317
  • 51445 - (Trans)glycosidases
  • 52317 - Class I glutamine amidotransferase-like
  • 0Direct
    49899,52540
  • 49899 - Concanavalin A-like lectins/glucanases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    52799,52799
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 0Direct
    46919,53098
  • 46919 - N-terminal Zn binding domain of HIV integrase
  • 53098 - Ribonuclease H-like
  • 0Direct
    56731,52540
  • 56731 - DNA primase core
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    143791,143791
  • 143791 - DUSP-like
  • 143791 - DUSP-like
  • 0Direct
    53335,142877
  • 53335 - S-adenosyl-L-methionine-dependent methyltransferases
  • 142877 - EndoU-like
  • 0Direct
    48024,52540
  • 48024 - N-terminal domain of DnaB helicase
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    47090,55486
  • 47090 - PGBD-like
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 0Direct
    53474,49723
  • 53474 - alpha/beta-Hydrolases
  • 49723 - Lipase/lipooxygenase domain (PLAT/LH2 domain)
  • 0Direct
    49854,57424
  • 49854 - Spermadhesin, CUB domain
  • 57424 - LDL receptor-like module
  • 0Direct
    53098,53098
  • 53098 - Ribonuclease H-like
  • 53098 - Ribonuclease H-like
  • 0Direct
    50729,52799
  • 50729 - PH domain-like
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 0Direct
    64571,64571
  • 64571 - Cellulose docking domain, dockering
  • 64571 - Cellulose docking domain, dockering
  • 0Direct
    51069,49265
  • 51069 - Carbonic anhydrase
  • 49265 - Fibronectin type III
  • 0Direct
    53067,109604
  • 53067 - Actin-like ATPase domain
  • 109604 - HD-domain/PDEase-like
  • 0Direct
    55608,52540
  • 55608 - Homing endonucleases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    50156,52799
  • 50156 - PDZ domain-like
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 0Direct
    50447,54980
  • 50447 - Translation proteins
  • 54980 - EF-G C-terminal domain-like
  • 0Direct
    57184,50494
  • 57184 - Growth factor receptor domain
  • 50494 - Trypsin-like serine proteases
  • 0Direct
    75005,49899
  • 75005 - Arabinanase/levansucrase/invertase
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0Direct
    100939,68906
  • 100939 - SPOC domain-like
  • 68906 - SAP domain
  • 0Direct
    110083,55909
  • 110083 - Peptidylarginine deiminase Pad4, middle domain
  • 55909 - Pentein
  • 0Direct
    57440,57440
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 0Direct
    49899,57180
  • 49899 - Concanavalin A-like lectins/glucanases
  • 57180 - Cellulose-binding domain
  • 0Direct
    49303,51445
  • 49303 - beta-Galactosidase/glucuronidase domain
  • 51445 - (Trans)glycosidases
  • 0Direct
    52087,52799
  • 52087 - CRAL/TRIO domain
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 0Direct
    49265,51445
  • 49265 - Fibronectin type III
  • 51445 - (Trans)glycosidases
  • 0Direct
    81761,53474
  • 81761 - X-Prolyl dipeptidyl aminopeptidase PepX, N-terminal domain
  • 53474 - alpha/beta-Hydrolases
  • 0Direct
    50199,63748
  • 50199 - Staphylococcal nuclease
  • 63748 - Tudor/PWWP/MBT
  • 0Direct
    56371,50370
  • 56371 - Ribosome inactivating proteins (RIP)
  • 50370 - Ricin B-like lectins
  • 0Direct
    47353,57756
  • 47353 - Retrovirus capsid dimerization domain-like
  • 57756 - Retrovirus zinc finger-like domains
  • 0Direct
    50331,50331
  • 50331 - MOP-like
  • 50331 - MOP-like
  • 0Direct
    48452,56300
  • 48452 - TPR-like
  • 56300 - Metallo-dependent phosphatases
  • 0Direct
    58091,49899
  • 58091 - Clostridium neurotoxins, "coiled-coil" domain
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0Direct
    63433,56529
  • 63433 - Fumarylacetoacetate hydrolase, FAH, N-terminal domain
  • 56529 - FAH
  • 0Direct
    49384,57615
  • 49384 - Carbohydrate-binding domain
  • 57615 - Type X cellulose binding domain, CBDX
  • 0Direct
    55486,82895
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 82895 - TSP-1 type 1 repeat
  • 0Direct
    90188,90188
  • 90188 - Somatomedin B domain
  • 90188 - Somatomedin B domain
  • 0Direct
    52283,51735
  • 52283 - Formate/glycerate dehydrogenase catalytic domain-like
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 0Direct
    117100,49785
  • 117100 - Beta-galactosidase LacA, domain 3
  • 49785 - Galactose-binding domain-like
  • 0Direct
    50974,50974
  • 50974 - Nitrous oxide reductase, N-terminal domain
  • 50974 - Nitrous oxide reductase, N-terminal domain
  • 0Direct
    56568,47233
  • 56568 - Non-globular alpha+beta subunits of globular proteins
  • 47233 - Bacterial GAP domain
  • 0Direct
    52540,90123
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 90123 - ABC transporter transmembrane region
  • 0Direct
    51206,51206
  • 51206 - cAMP-binding domain-like
  • 51206 - cAMP-binding domain-like
  • 0Direct
    54211,54211
  • 54211 - Ribosomal protein S5 domain 2-like
  • 54211 - Ribosomal protein S5 domain 2-like
  • 0Direct
    47943,47353
  • 47943 - Retrovirus capsid protein, N-terminal core domain
  • 47353 - Retrovirus capsid dimerization domain-like
  • 0Direct
    82171,53474
  • 82171 - DPP6 N-terminal domain-like
  • 53474 - alpha/beta-Hydrolases
  • 0Direct
    74924,54001
  • 74924 - Cap-Gly domain
  • 54001 - Cysteine proteinases
  • 0Direct
    52317,141986
  • 52317 - Class I glutamine amidotransferase-like
  • 141986 - LD-carboxypeptidase A C-terminal domain-like
  • 0Direct
    53639,56784
  • 53639 - AraD/HMP-PK domain-like
  • 56784 - HAD-like
  • 0Direct
    49464,53187
  • 49464 - Carboxypeptidase regulatory domain-like
  • 53187 - Zn-dependent exopeptidases
  • 0Direct
    56601,52091
  • 56601 - beta-lactamase/transpeptidase-like
  • 52091 - SpoIIaa-like
  • 0Direct
    57440,57196
  • 57440 - Kringle-like
  • 57196 - EGF/Laminin
  • 0Direct
    143791,54236
  • 143791 - DUSP-like
  • 54236 - Ubiquitin-like
  • 0Direct
    55486,57552
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 57552 - Blood coagulation inhibitor (disintegrin)
  • 0Direct
    50156,52096
  • 50156 - PDZ domain-like
  • 52096 - ClpP/crotonase
  • 0Direct
    49899,49854
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49854 - Spermadhesin, CUB domain
  • 0Direct
    52540,51294
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 51294 - Hedgehog/intein (Hint) domain
  • 0Direct
    49384,49265
  • 49384 - Carbohydrate-binding domain
  • 49265 - Fibronectin type III
  • 0Direct
    51294,52540
  • 51294 - Hedgehog/intein (Hint) domain
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    55781,55781
  • 55781 - GAF domain-like
  • 55781 - GAF domain-like
  • 0Direct
    52540,55144
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 55144 - LigT-like
  • 0Direct
    51445,49344
  • 51445 - (Trans)glycosidases
  • 49344 - CBD9-like
  • 0Direct
    159936,52949
  • 159936 - NSP3A-like
  • 52949 - Macro domain-like
  • 0Direct
    100895,56487
  • 100895 - Kazal-type serine protease inhibitors
  • 56487 - SRCR-like
  • 0Direct
    50370,50370
  • 50370 - Ricin B-like lectins
  • 50370 - Ricin B-like lectins
  • 0Direct
    53649,54060
  • 53649 - Alkaline phosphatase-like
  • 54060 - His-Me finger endonucleases
  • 0Direct
    55486,50923
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 50923 - Hemopexin-like domain
  • 0Direct
    51445,52279
  • 51445 - (Trans)glycosidases
  • 52279 - Beta-D-glucan exohydrolase, C-terminal domain
  • 0Direct
    52949,53187
  • 52949 - Macro domain-like
  • 53187 - Zn-dependent exopeptidases
  • 0Direct
    52156,50447
  • 52156 - Initiation factor IF2/eIF5b, domain 3
  • 50447 - Translation proteins
  • 0Direct
    52172,52738
  • 52172 - CheY-like
  • 52738 - Methylesterase CheB, C-terminal domain
  • 0Direct
    50630,56672
  • 50630 - Acid proteases
  • 56672 - DNA/RNA polymerases
  • 0Direct
    49299,89260
  • 49299 - PKD domain
  • 89260 - Collagen-binding domain
  • 0Direct
    50249,56300
  • 50249 - Nucleic acid-binding proteins
  • 56300 - Metallo-dependent phosphatases
  • 0Direct
    54001,55205
  • 54001 - Cysteine proteinases
  • 55205 - EPT/RTPC-like
  • 0Direct
    56784,54427
  • 56784 - HAD-like
  • 54427 - NTF2-like
  • 0Direct
    52151,51412
  • 52151 - FabD/lysophospholipase-like
  • 51412 - Inosine monophosphate dehydrogenase (IMPDH)
  • 0Direct
    56219,54928
  • 56219 - DNase I-like
  • 54928 - RNA-binding domain, RBD
  • 0Direct
    56672,53098
  • 56672 - DNA/RNA polymerases
  • 53098 - Ribonuclease H-like
  • 0Direct
    46785,158702
  • 46785 - "Winged helix" DNA-binding domain
  • 158702 - Sec63 N-terminal domain-like
  • 0Direct
    74650,51445
  • 74650 - Galactose mutarotase-like
  • 51445 - (Trans)glycosidases
  • 0Direct
    46785,47819
  • 46785 - "Winged helix" DNA-binding domain
  • 47819 - HRDC-like
  • 0Direct
    51445,64571
  • 51445 - (Trans)glycosidases
  • 64571 - Cellulose docking domain, dockering
  • 0Direct
    52540,53254
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 53254 - Phosphoglycerate mutase-like
  • 0.00000000000000226Direct
    50156,50156
  • 50156 - PDZ domain-like
  • 50156 - PDZ domain-like
  • 0.000000000000003983Direct
    49265,49265
  • 49265 - Fibronectin type III
  • 49265 - Fibronectin type III
  • 0.000000000001233Direct
    54106,54106
  • 54106 - LysM domain
  • 54106 - LysM domain
  • 0.000000000008281Direct
    88688,74650
  • 88688 - Families 57/38 glycoside transferase middle domain
  • 74650 - Galactose mutarotase-like
  • 0.000000000116Direct
    51735,52283
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 52283 - Formate/glycerate dehydrogenase catalytic domain-like
  • 0.0000000001704Direct
    53955,56601
  • 53955 - Lysozyme-like
  • 56601 - beta-lactamase/transpeptidase-like
  • 0.0000000001704Direct
    53927,53597
  • 53927 - Cytidine deaminase-like
  • 53597 - Dihydrofolate reductase-like
  • 0.0000000004958Direct
    57756,57756
  • 57756 - Retrovirus zinc finger-like domains
  • 57756 - Retrovirus zinc finger-like domains
  • 0.00000003801Direct
    55550,55550
  • 55550 - SH2 domain
  • 55550 - SH2 domain
  • 0.00000005601Direct
    51445,51445
  • 51445 - (Trans)glycosidases
  • 51445 - (Trans)glycosidases
  • 0.00000007123Direct
    52799,49562
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 0.0000002233Direct
    64268,50729
  • 64268 - PX domain
  • 50729 - PH domain-like
  • 0.000001459Direct
    51294,55608
  • 51294 - Hedgehog/intein (Hint) domain
  • 55608 - Homing endonucleases
  • 0.000006987Direct
    55073,141868
  • 55073 - Nucleotide cyclase
  • 141868 - EAL domain-like
  • 0.00002953Direct
    51011,49452
  • 51011 - Glycosyl hydrolase domain
  • 49452 - Starch-binding domain-like
  • 0.00002953Direct
    51197,52540
  • 51197 - Clavaminate synthase-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.00004646Direct
    48403,52540
  • 48403 - Ankyrin repeat
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.00004957Direct
    54637,54637
  • 54637 - Thioesterase/thiol ester dehydrase-isomerase
  • 54637 - Thioesterase/thiol ester dehydrase-isomerase
  • 0.00006371Direct
    160467,50891
  • 160467 - PH0987 N-terminal domain-like
  • 50891 - Cyclophilin-like
  • 0.0001332Direct
    52335,51556
  • 52335 - Methylglyoxal synthase-like
  • 51556 - Metallo-dependent hydrolases
  • 0.0001841Direct
    63748,50199
  • 63748 - Tudor/PWWP/MBT
  • 50199 - Staphylococcal nuclease
  • 0.0001868Direct
    48726,49265
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 0.0003832Direct
    49899,50939
  • 49899 - Concanavalin A-like lectins/glucanases
  • 50939 - Sialidases
  • 0.0005988Direct
    54849,52029
  • 54849 - GroEL-intermediate domain like
  • 52029 - GroEL apical domain-like
  • 0.0006698Direct
    54236,47031
  • 54236 - Ubiquitin-like
  • 47031 - Second domain of FERM
  • 0.001064Inherited
    54768,54768
  • 54768 - dsRNA-binding domain-like
  • 54768 - dsRNA-binding domain-like
  • 0.002374Inherited
    56712,51294
  • 56712 - Prokaryotic type I DNA topoisomerase
  • 51294 - Hedgehog/intein (Hint) domain
  • 0.002692Inherited
    90209,90209
  • 90209 - Ran binding protein zinc finger-like
  • 90209 - Ran binding protein zinc finger-like
  • 0.002692Inherited
    49785,81296
  • 49785 - Galactose-binding domain-like
  • 81296 - E set domains
  • 0.002878Inherited
    52317,52440
  • 52317 - Class I glutamine amidotransferase-like
  • 52440 - PreATP-grasp domain
  • 0.005017Inherited
    47031,50729
  • 47031 - Second domain of FERM
  • 50729 - PH domain-like
  • 0.01091Inherited
    47336,53474
  • 47336 - ACP-like
  • 53474 - alpha/beta-Hydrolases
  • 0.01158Inherited
    53474,53335
  • 53474 - alpha/beta-Hydrolases
  • 53335 - S-adenosyl-L-methionine-dependent methyltransferases
  • 0.02671Inherited
    100950,100950
  • 100950 - NagB/RpiA/CoA transferase-like
  • 100950 - NagB/RpiA/CoA transferase-like
  • 0.05209Inherited
    81301,81271
  • 81301 - Nucleotidyltransferase
  • 81271 - TGS-like
  • 0.1115Inherited
    55945,48150
  • 55945 - TATA-box binding protein-like
  • 48150 - DNA-glycosylase
  • 0.1253Inherited
    81296,51445
  • 81296 - E set domains
  • 51445 - (Trans)glycosidases
  • 0.1485Inherited
    54236,54236
  • 54236 - Ubiquitin-like
  • 54236 - Ubiquitin-like
  • 0.173Inherited
    109604,81301
  • 109604 - HD-domain/PDEase-like
  • 81301 - Nucleotidyltransferase
  • 0.2089Inherited
    74650,48208
  • 74650 - Galactose mutarotase-like
  • 48208 - Six-hairpin glycosidases
  • 0.2845Inherited
    49899,49899
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.3398Inherited
    53756,56784
  • 53756 - UDP-Glycosyltransferase/glycogen phosphorylase
  • 56784 - HAD-like
  • 0.3754Inherited
    47060,55681
  • 47060 - S15/NS1 RNA-binding domain
  • 55681 - Class II aaRS and biotin synthetases
  • 0.4572Inherited
    56024,56024
  • 56024 - Phospholipase D/nuclease
  • 56024 - Phospholipase D/nuclease
  • 0.5488Inherited
    52540,48019
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 48019 - post-AAA+ oligomerization domain-like
  • 0.6751Inherited
    49785,57184
  • 49785 - Galactose-binding domain-like
  • 57184 - Growth factor receptor domain
  • 0.7167Inherited
    52058,52058
  • 52058 - L domain-like
  • 52058 - L domain-like
  • 0.8184Inherited
    51735,51735
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 0.8336Inherited
    51735,47336
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 47336 - ACP-like
  • 0.8392Inherited
    52021,52317
  • 52021 - Carbamoyl phosphate synthetase, small subunit N-terminal domain
  • 52317 - Class I glutamine amidotransferase-like
  • 1Inherited
    52518,52467
  • 52518 - Thiamin diphosphate-binding fold (THDP-binding)
  • 52467 - DHS-like NAD/FAD-binding domain
  • 1Inherited
    56059,48108
  • 56059 - Glutathione synthetase ATP-binding domain-like
  • 48108 - Carbamoyl phosphate synthetase, large subunit connection domain
  • 1Inherited
    52467,52518
  • 52467 - DHS-like NAD/FAD-binding domain
  • 52518 - Thiamin diphosphate-binding fold (THDP-binding)
  • 1Inherited
    52440,56059
  • 52440 - PreATP-grasp domain
  • 56059 - Glutathione synthetase ATP-binding domain-like
  • 1Inherited
    56059,52335
  • 56059 - Glutathione synthetase ATP-binding domain-like
  • 52335 - Methylglyoxal synthase-like
  • 1Inherited
    51735,56327
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 56327 - LDH C-terminal domain-like
  • 1Inherited
    56091,50249
  • 56091 - DNA ligase/mRNA capping enzyme, catalytic domain
  • 50249 - Nucleic acid-binding proteins
  • 1Inherited
    48108,52440
  • 48108 - Carbamoyl phosphate synthetase, large subunit connection domain
  • 52440 - PreATP-grasp domain
  • 1Inherited
    50129,51735
  • 50129 - GroES-like
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 1Inherited
    53098,56672
  • 53098 - Ribonuclease H-like
  • 56672 - DNA/RNA polymerases
  • 1Inherited
    48726,48726
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 1Inherited
    48239,48576
  • 48239 - Terpenoid cyclases/Protein prenyltransferases
  • 48576 - Terpenoid synthases
  • 1Inherited
    53067,53067
  • 53067 - Actin-like ATPase domain
  • 53067 - Actin-like ATPase domain
  • 1Inherited
    52151,55048
  • 52151 - FabD/lysophospholipase-like
  • 55048 - Probable ACP-binding domain of malonyl-CoA ACP transacylase
  • 1Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    49464,53187,49464
  • 49464 - Carboxypeptidase regulatory domain-like
  • 53187 - Zn-dependent exopeptidases
  • 49464 - Carboxypeptidase regulatory domain-like
  • 0Direct
    57196,49854,57535
  • 57196 - EGF/Laminin
  • 49854 - Spermadhesin, CUB domain
  • 57535 - Complement control module/SCR domain
  • 0Direct
    56672,53098,50122
  • 56672 - DNA/RNA polymerases
  • 53098 - Ribonuclease H-like
  • 50122 - DNA-binding domain of retroviral integrase
  • 0Direct
    48592,54849,52029
  • 48592 - GroEL equatorial domain-like
  • 54849 - GroEL-intermediate domain like
  • 52029 - GroEL apical domain-like
  • 0Direct
    81660,56784,81665
  • 81660 - Metal cation-transporting ATPase, ATP-binding domain N
  • 56784 - HAD-like
  • 81665 - Calcium ATPase, transmembrane domain M
  • 0Direct
    50692,54585,52540
  • 50692 - ADC-like
  • 54585 - Cdc48 domain 2-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    51197,52540,56672
  • 51197 - Clavaminate synthase-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 56672 - DNA/RNA polymerases
  • 0Direct
    52540,50331,50331
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 50331 - MOP-like
  • 50331 - MOP-like
  • 0Direct
    50615,52540,47917
  • 50615 - N-terminal domain of alpha and beta subunits of F1 ATP synthase
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 47917 - C-terminal domain of alpha and beta subunits of F1 ATP synthase
  • 0Direct
    63737,55486,48371
  • 63737 - Leukotriene A4 hydrolase N-terminal domain
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 48371 - ARM repeat
  • 0Direct
    54001,88633,88633
  • 54001 - Cysteine proteinases
  • 88633 - Positive stranded ssRNA viruses
  • 88633 - Positive stranded ssRNA viruses
  • 0Direct
    47473,51695,49562
  • 47473 - EF-hand
  • 51695 - PLC-like phosphodiesterases
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 0Direct
    49854,57424,57424
  • 49854 - Spermadhesin, CUB domain
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 0Direct
    52025,53187,47672
  • 52025 - PA domain
  • 53187 - Zn-dependent exopeptidases
  • 47672 - Transferrin receptor-like dimerisation domain
  • 0Direct
    52540,50447,54980
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 50447 - Translation proteins
  • 54980 - EF-G C-terminal domain-like
  • 0Direct
    52540,52540,47370
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 47370 - Bromodomain
  • 0Direct
    50199,63748,50199
  • 50199 - Staphylococcal nuclease
  • 63748 - Tudor/PWWP/MBT
  • 50199 - Staphylococcal nuclease
  • 0Direct
    54160,54160,52540
  • 54160 - Chromo domain-like
  • 54160 - Chromo domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    82708,53098,54928
  • 82708 - R3H domain
  • 53098 - Ribonuclease H-like
  • 54928 - RNA-binding domain, RBD
  • 0Direct
    51294,55608,52540
  • 51294 - Hedgehog/intein (Hint) domain
  • 55608 - Homing endonucleases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    52540,56712,51294
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 56712 - Prokaryotic type I DNA topoisomerase
  • 51294 - Hedgehog/intein (Hint) domain
  • 0Direct
    57535,57535,57535
  • 57535 - Complement control module/SCR domain
  • 57535 - Complement control module/SCR domain
  • 57535 - Complement control module/SCR domain
  • 0Direct
    46785,158702,52540
  • 46785 - "Winged helix" DNA-binding domain
  • 158702 - Sec63 N-terminal domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    53092,53092,55920
  • 53092 - Creatinase/prolidase N-terminal domain
  • 53092 - Creatinase/prolidase N-terminal domain
  • 55920 - Creatinase/aminopeptidase
  • 0Direct
    89043,50494,56672
  • 89043 - Soluble domain of poliovirus core protein 3a
  • 50494 - Trypsin-like serine proteases
  • 56672 - DNA/RNA polymerases
  • 0Direct
    55486,58091,49899
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 58091 - Clostridium neurotoxins, "coiled-coil" domain
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0Direct
    46785,158702,81296
  • 46785 - "Winged helix" DNA-binding domain
  • 158702 - Sec63 N-terminal domain-like
  • 81296 - E set domains
  • 0Direct
    49854,49899,49854
  • 49854 - Spermadhesin, CUB domain
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49854 - Spermadhesin, CUB domain
  • 0Direct
    48024,52540,51294
  • 48024 - N-terminal domain of DnaB helicase
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 51294 - Hedgehog/intein (Hint) domain
  • 0Direct
    52540,89043,50494
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 89043 - Soluble domain of poliovirus core protein 3a
  • 50494 - Trypsin-like serine proteases
  • 0Direct
    56371,50370,50370
  • 56371 - Ribosome inactivating proteins (RIP)
  • 50370 - Ricin B-like lectins
  • 50370 - Ricin B-like lectins
  • 0Direct
    57535,53300,50494
  • 57535 - Complement control module/SCR domain
  • 53300 - vWA-like
  • 50494 - Trypsin-like serine proteases
  • 0Direct
    50729,56024,56024
  • 50729 - PH domain-like
  • 56024 - Phospholipase D/nuclease
  • 56024 - Phospholipase D/nuclease
  • 0Direct
    55781,55781,55781
  • 55781 - GAF domain-like
  • 55781 - GAF domain-like
  • 55781 - GAF domain-like
  • 0Direct
    47090,55486,50923
  • 47090 - PGBD-like
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 50923 - Hemopexin-like domain
  • 0Direct
    58091,49899,50386
  • 58091 - Clostridium neurotoxins, "coiled-coil" domain
  • 49899 - Concanavalin A-like lectins/glucanases
  • 50386 - STI-like
  • 0Direct
    50044,51695,49562
  • 50044 - SH3-domain
  • 51695 - PLC-like phosphodiesterases
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 0Direct
    49854,49854,50494
  • 49854 - Spermadhesin, CUB domain
  • 49854 - Spermadhesin, CUB domain
  • 50494 - Trypsin-like serine proteases
  • 0Direct
    81296,48208,63446
  • 81296 - E set domains
  • 48208 - Six-hairpin glycosidases
  • 63446 - Type I dockerin domain
  • 0Direct
    54001,49758,47473
  • 54001 - Cysteine proteinases
  • 49758 - Calpain large subunit, middle domain (domain III)
  • 47473 - EF-hand
  • 0Direct
    53067,100920,100934
  • 53067 - Actin-like ATPase domain
  • 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
  • 100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain
  • 0Direct
    46938,52087,52799
  • 46938 - CRAL/TRIO N-terminal domain
  • 52087 - CRAL/TRIO domain
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 0Direct
    64268,50729,56024
  • 64268 - PX domain
  • 50729 - PH domain-like
  • 56024 - Phospholipase D/nuclease
  • 0Direct
    57424,57424,50494
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 50494 - Trypsin-like serine proteases
  • 0Direct
    90188,53649,54060
  • 90188 - Somatomedin B domain
  • 53649 - Alkaline phosphatase-like
  • 54060 - His-Me finger endonucleases
  • 0Direct
    50199,50199,50199
  • 50199 - Staphylococcal nuclease
  • 50199 - Staphylococcal nuclease
  • 50199 - Staphylococcal nuclease
  • 0Direct
    51445,64571,64571
  • 51445 - (Trans)glycosidases
  • 64571 - Cellulose docking domain, dockering
  • 64571 - Cellulose docking domain, dockering
  • 0Direct
    55781,55781,109604
  • 55781 - GAF domain-like
  • 55781 - GAF domain-like
  • 109604 - HD-domain/PDEase-like
  • 0Direct
    52540,49899,52540
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 49899 - Concanavalin A-like lectins/glucanases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    51445,49303,49303
  • 51445 - (Trans)glycosidases
  • 49303 - beta-Galactosidase/glucuronidase domain
  • 49303 - beta-Galactosidase/glucuronidase domain
  • 0Direct
    56672,53098,53098
  • 56672 - DNA/RNA polymerases
  • 53098 - Ribonuclease H-like
  • 53098 - Ribonuclease H-like
  • 0Direct
    81296,51445,54556
  • 81296 - E set domains
  • 51445 - (Trans)glycosidases
  • 54556 - Chitinase insertion domain
  • 0Direct
    57414,57440,57440
  • 57414 - Hairpin loop containing domain-like
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 0Direct
    55550,50044,51695
  • 55550 - SH2 domain
  • 50044 - SH3-domain
  • 51695 - PLC-like phosphodiesterases
  • 0Direct
    49899,49854,57424
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49854 - Spermadhesin, CUB domain
  • 57424 - LDL receptor-like module
  • 0Direct
    50447,54980,54980
  • 50447 - Translation proteins
  • 54980 - EF-G C-terminal domain-like
  • 54980 - EF-G C-terminal domain-like
  • 0Direct
    54001,143791,143791
  • 54001 - Cysteine proteinases
  • 143791 - DUSP-like
  • 143791 - DUSP-like
  • 0Direct
    55550,55550,52799
  • 55550 - SH2 domain
  • 55550 - SH2 domain
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 0Direct
    56672,52540,52540
  • 56672 - DNA/RNA polymerases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    56784,54211,54211
  • 56784 - HAD-like
  • 54211 - Ribosomal protein S5 domain 2-like
  • 54211 - Ribosomal protein S5 domain 2-like
  • 0Direct
    53955,54106,54106
  • 53955 - Lysozyme-like
  • 54106 - LysM domain
  • 54106 - LysM domain
  • 0Direct
    53300,100939,68906
  • 53300 - vWA-like
  • 100939 - SPOC domain-like
  • 68906 - SAP domain
  • 0Direct
    55545,51445,140657
  • 55545 - beta-N-acetylhexosaminidase-like domain
  • 51445 - (Trans)glycosidases
  • 140657 - Hyaluronidase post-catalytic domain-like
  • 0Direct
    63411,63411,63411
  • 63411 - LuxS/MPP-like metallohydrolase
  • 63411 - LuxS/MPP-like metallohydrolase
  • 63411 - LuxS/MPP-like metallohydrolase
  • 0Direct
    140367,143076,101816
  • 140367 - Coronavirus NSP7-like
  • 143076 - Coronavirus NSP8-like
  • 101816 - Replicase NSP9
  • 0Direct
    50630,56672,53098
  • 50630 - Acid proteases
  • 56672 - DNA/RNA polymerases
  • 53098 - Ribonuclease H-like
  • 0Direct
    56487,57424,57424
  • 56487 - SRCR-like
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 0Direct
    52540,54980,54980
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 54980 - EF-G C-terminal domain-like
  • 54980 - EF-G C-terminal domain-like
  • 0Direct
    52540,90123,52540
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 90123 - ABC transporter transmembrane region
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    57440,57440,50494
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 50494 - Trypsin-like serine proteases
  • 0Direct
    52743,49785,57184
  • 52743 - Subtilisin-like
  • 49785 - Galactose-binding domain-like
  • 57184 - Growth factor receptor domain
  • 0Direct
    57603,57440,57440
  • 57603 - FnI-like domain
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 0Direct
    47353,57756,50630
  • 47353 - Retrovirus capsid dimerization domain-like
  • 57756 - Retrovirus zinc finger-like domains
  • 50630 - Acid proteases
  • 0Direct
    51445,51011,50370
  • 51445 - (Trans)glycosidases
  • 51011 - Glycosyl hydrolase domain
  • 50370 - Ricin B-like lectins
  • 0Direct
    52540,52540,46785
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 46785 - "Winged helix" DNA-binding domain
  • 0Direct
    55008,55008,55008
  • 55008 - HMA, heavy metal-associated domain
  • 55008 - HMA, heavy metal-associated domain
  • 55008 - HMA, heavy metal-associated domain
  • 0Direct
    49785,49785,51445
  • 49785 - Galactose-binding domain-like
  • 49785 - Galactose-binding domain-like
  • 51445 - (Trans)glycosidases
  • 0Direct
    49785,49303,51445
  • 49785 - Galactose-binding domain-like
  • 49303 - beta-Galactosidase/glucuronidase domain
  • 51445 - (Trans)glycosidases
  • 0Direct
    49562,54236,54236
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 54236 - Ubiquitin-like
  • 54236 - Ubiquitin-like
  • 0Direct
    52540,52540,56712
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 56712 - Prokaryotic type I DNA topoisomerase
  • 0Direct
    50494,56672,88633
  • 50494 - Trypsin-like serine proteases
  • 56672 - DNA/RNA polymerases
  • 88633 - Positive stranded ssRNA viruses
  • 0Direct
    117100,49785,49785
  • 117100 - Beta-galactosidase LacA, domain 3
  • 49785 - Galactose-binding domain-like
  • 49785 - Galactose-binding domain-like
  • 0Direct
    82895,82895,82895
  • 82895 - TSP-1 type 1 repeat
  • 82895 - TSP-1 type 1 repeat
  • 82895 - TSP-1 type 1 repeat
  • 0Direct
    57424,49854,49899
  • 57424 - LDL receptor-like module
  • 49854 - Spermadhesin, CUB domain
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0Direct
    51338,51556,51338
  • 51338 - Composite domain of metallo-dependent hydrolases
  • 51556 - Metallo-dependent hydrolases
  • 51338 - Composite domain of metallo-dependent hydrolases
  • 0Direct
    51283,50630,56672
  • 51283 - dUTPase-like
  • 50630 - Acid proteases
  • 56672 - DNA/RNA polymerases
  • 0Direct
    54585,52540,52540
  • 54585 - Cdc48 domain 2-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    55550,55550,50044
  • 55550 - SH2 domain
  • 55550 - SH2 domain
  • 50044 - SH3-domain
  • 0Direct
    81653,81665,56784
  • 81653 - Calcium ATPase, transduction domain A
  • 81665 - Calcium ATPase, transmembrane domain M
  • 56784 - HAD-like
  • 0Direct
    47986,47986,52129
  • 47986 - DEATH domain
  • 47986 - DEATH domain
  • 52129 - Caspase-like
  • 0Direct
    56601,50886,50886
  • 56601 - beta-lactamase/transpeptidase-like
  • 50886 - D-aminopeptidase, middle and C-terminal domains
  • 50886 - D-aminopeptidase, middle and C-terminal domains
  • 0Direct
    47943,47353,57756
  • 47943 - Retrovirus capsid protein, N-terminal core domain
  • 47353 - Retrovirus capsid dimerization domain-like
  • 57756 - Retrovirus zinc finger-like domains
  • 0Direct
    51011,51445,51011
  • 51011 - Glycosyl hydrolase domain
  • 51445 - (Trans)glycosidases
  • 51011 - Glycosyl hydrolase domain
  • 0Direct
    57756,57756,51283
  • 57756 - Retrovirus zinc finger-like domains
  • 57756 - Retrovirus zinc finger-like domains
  • 51283 - dUTPase-like
  • 0Direct
    158702,52540,52540
  • 158702 - Sec63 N-terminal domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    56672,53098,46919
  • 56672 - DNA/RNA polymerases
  • 53098 - Ribonuclease H-like
  • 46919 - N-terminal Zn binding domain of HIV integrase
  • 0Direct
    47353,57756,57756
  • 47353 - Retrovirus capsid dimerization domain-like
  • 57756 - Retrovirus zinc finger-like domains
  • 57756 - Retrovirus zinc finger-like domains
  • 0Direct
    54106,54106,54106
  • 54106 - LysM domain
  • 54106 - LysM domain
  • 54106 - LysM domain
  • 0Direct
    90188,90188,53649
  • 90188 - Somatomedin B domain
  • 90188 - Somatomedin B domain
  • 53649 - Alkaline phosphatase-like
  • 0Direct
    57630,57184,50494
  • 57630 - GLA-domain
  • 57184 - Growth factor receptor domain
  • 50494 - Trypsin-like serine proteases
  • 0Direct
    47836,47943,47353
  • 47836 - Retroviral matrix proteins
  • 47943 - Retrovirus capsid protein, N-terminal core domain
  • 47353 - Retrovirus capsid dimerization domain-like
  • 0Direct
    51283,46919,53098
  • 51283 - dUTPase-like
  • 46919 - N-terminal Zn binding domain of HIV integrase
  • 53098 - Ribonuclease H-like
  • 0Direct
    57630,57196,57196
  • 57630 - GLA-domain
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0Direct
    50494,52540,89043
  • 50494 - Trypsin-like serine proteases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 89043 - Soluble domain of poliovirus core protein 3a
  • 0Direct
    51445,52317,51011
  • 51445 - (Trans)glycosidases
  • 52317 - Class I glutamine amidotransferase-like
  • 51011 - Glycosyl hydrolase domain
  • 0Direct
    50494,52540,52540
  • 50494 - Trypsin-like serine proteases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    54897,52743,49785
  • 54897 - Protease propeptides/inhibitors
  • 52743 - Subtilisin-like
  • 49785 - Galactose-binding domain-like
  • 0Direct
    53300,100939,101420
  • 53300 - vWA-like
  • 100939 - SPOC domain-like
  • 101420 - C-terminal domain of Ku80
  • 0Direct
    51197,52540,52540
  • 51197 - Clavaminate synthase-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    90123,52540,90123
  • 90123 - ABC transporter transmembrane region
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 90123 - ABC transporter transmembrane region
  • 0Direct
    55486,57440,57440
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 0Direct
    82671,49854,49854
  • 82671 - SEA domain
  • 49854 - Spermadhesin, CUB domain
  • 49854 - Spermadhesin, CUB domain
  • 0Direct
    88633,88633,88633
  • 88633 - Positive stranded ssRNA viruses
  • 88633 - Positive stranded ssRNA viruses
  • 88633 - Positive stranded ssRNA viruses
  • 0Direct
    50249,52540,52540
  • 50249 - Nucleic acid-binding proteins
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    57535,57535,53300
  • 57535 - Complement control module/SCR domain
  • 57535 - Complement control module/SCR domain
  • 53300 - vWA-like
  • 0Direct
    52540,52540,47819
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 47819 - HRDC-like
  • 0Direct
    54106,54106,54001
  • 54106 - LysM domain
  • 54106 - LysM domain
  • 54001 - Cysteine proteinases
  • 0Direct
    53187,49464,53187
  • 53187 - Zn-dependent exopeptidases
  • 49464 - Carboxypeptidase regulatory domain-like
  • 53187 - Zn-dependent exopeptidases
  • 0Direct
    81665,81660,56784
  • 81665 - Calcium ATPase, transmembrane domain M
  • 81660 - Metal cation-transporting ATPase, ATP-binding domain N
  • 56784 - HAD-like
  • 0Direct
    143503,54001,49785
  • 143503 - PUG domain-like
  • 54001 - Cysteine proteinases
  • 49785 - Galactose-binding domain-like
  • 0Direct
    53098,47819,47819
  • 53098 - Ribonuclease H-like
  • 47819 - HRDC-like
  • 47819 - HRDC-like
  • 0Direct
    49899,48726,49265
  • 49899 - Concanavalin A-like lectins/glucanases
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 0Direct
    54768,54768,54768
  • 54768 - dsRNA-binding domain-like
  • 54768 - dsRNA-binding domain-like
  • 54768 - dsRNA-binding domain-like
  • 0Direct
    56024,56024,56024
  • 56024 - Phospholipase D/nuclease
  • 56024 - Phospholipase D/nuclease
  • 56024 - Phospholipase D/nuclease
  • 0Direct
    81653,81665,81660
  • 81653 - Calcium ATPase, transduction domain A
  • 81665 - Calcium ATPase, transmembrane domain M
  • 81660 - Metal cation-transporting ATPase, ATP-binding domain N
  • 0Direct
    52540,48403,52540
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 48403 - Ankyrin repeat
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    57535,57535,50494
  • 57535 - Complement control module/SCR domain
  • 57535 - Complement control module/SCR domain
  • 50494 - Trypsin-like serine proteases
  • 0Direct
    143076,101816,144246
  • 143076 - Coronavirus NSP8-like
  • 101816 - Replicase NSP9
  • 144246 - Coronavirus NSP10-like
  • 0Direct
    56672,53098,51283
  • 56672 - DNA/RNA polymerases
  • 53098 - Ribonuclease H-like
  • 51283 - dUTPase-like
  • 0Direct
    47090,55486,57440
  • 47090 - PGBD-like
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 57440 - Kringle-like
  • 0Direct
    50199,50199,63748
  • 50199 - Staphylococcal nuclease
  • 50199 - Staphylococcal nuclease
  • 63748 - Tudor/PWWP/MBT
  • 0Direct
    46919,53098,50122
  • 46919 - N-terminal Zn binding domain of HIV integrase
  • 53098 - Ribonuclease H-like
  • 50122 - DNA-binding domain of retroviral integrase
  • 0Direct
    51445,51011,117100
  • 51445 - (Trans)glycosidases
  • 51011 - Glycosyl hydrolase domain
  • 117100 - Beta-galactosidase LacA, domain 3
  • 0Direct
    57630,57440,57440
  • 57630 - GLA-domain
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 0Direct
    74650,51445,51011
  • 74650 - Galactose mutarotase-like
  • 51445 - (Trans)glycosidases
  • 51011 - Glycosyl hydrolase domain
  • 0Direct
    141734,101386,53720
  • 141734 - HisI-like
  • 101386 - all-alpha NTP pyrophosphatases
  • 53720 - ALDH-like
  • 0Direct
    55608,52540,47917
  • 55608 - Homing endonucleases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 47917 - C-terminal domain of alpha and beta subunits of F1 ATP synthase
  • 0Direct
    57440,57440,57440
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 0Direct
    57492,74650,51445
  • 57492 - Trefoil
  • 74650 - Galactose mutarotase-like
  • 51445 - (Trans)glycosidases
  • 0Direct
    52540,51294,52540
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 51294 - Hedgehog/intein (Hint) domain
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    82671,57424,49854
  • 82671 - SEA domain
  • 57424 - LDL receptor-like module
  • 49854 - Spermadhesin, CUB domain
  • 0Direct
    49785,51445,64571
  • 49785 - Galactose-binding domain-like
  • 51445 - (Trans)glycosidases
  • 64571 - Cellulose docking domain, dockering
  • 0Direct
    51445,49785,49785
  • 51445 - (Trans)glycosidases
  • 49785 - Galactose-binding domain-like
  • 49785 - Galactose-binding domain-like
  • 0Direct
    49854,57535,57535
  • 49854 - Spermadhesin, CUB domain
  • 57535 - Complement control module/SCR domain
  • 57535 - Complement control module/SCR domain
  • 0Direct
    54160,52540,52540
  • 54160 - Chromo domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    50729,47473,51695
  • 50729 - PH domain-like
  • 47473 - EF-hand
  • 51695 - PLC-like phosphodiesterases
  • 0Direct
    55545,51445,81296
  • 55545 - beta-N-acetylhexosaminidase-like domain
  • 51445 - (Trans)glycosidases
  • 81296 - E set domains
  • 0Direct
    57630,57196,50494
  • 57630 - GLA-domain
  • 57196 - EGF/Laminin
  • 50494 - Trypsin-like serine proteases
  • 0Direct
    57196,57196,50494
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 50494 - Trypsin-like serine proteases
  • 0Direct
    49265,49265,49265
  • 49265 - Fibronectin type III
  • 49265 - Fibronectin type III
  • 49265 - Fibronectin type III
  • 0Direct
    51445,49785,63446
  • 51445 - (Trans)glycosidases
  • 49785 - Galactose-binding domain-like
  • 63446 - Type I dockerin domain
  • 0Direct
    50494,50156,50156
  • 50494 - Trypsin-like serine proteases
  • 50156 - PDZ domain-like
  • 50156 - PDZ domain-like
  • 0Direct
    53098,46919,53098
  • 53098 - Ribonuclease H-like
  • 46919 - N-terminal Zn binding domain of HIV integrase
  • 53098 - Ribonuclease H-like
  • 0Direct
    81761,53474,49785
  • 81761 - X-Prolyl dipeptidyl aminopeptidase PepX, N-terminal domain
  • 53474 - alpha/beta-Hydrolases
  • 49785 - Galactose-binding domain-like
  • 0Direct
    69065,69065,54768
  • 69065 - RNase III domain-like
  • 69065 - RNase III domain-like
  • 54768 - dsRNA-binding domain-like
  • 0Direct
    52540,52156,50447
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52156 - Initiation factor IF2/eIF5b, domain 3
  • 50447 - Translation proteins
  • 0Direct
    55486,49899,49599
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49599 - TRAF domain-like
  • 0Direct
    51445,140657,49785
  • 51445 - (Trans)glycosidases
  • 140657 - Hyaluronidase post-catalytic domain-like
  • 49785 - Galactose-binding domain-like
  • 0Direct
    51011,117100,49785
  • 51011 - Glycosyl hydrolase domain
  • 117100 - Beta-galactosidase LacA, domain 3
  • 49785 - Galactose-binding domain-like
  • 0Direct
    50249,47781,46929
  • 50249 - Nucleic acid-binding proteins
  • 47781 - RuvA domain 2-like
  • 46929 - DNA helicase RuvA subunit, C-terminal domain
  • 0Direct
    49854,57424,56487
  • 49854 - Spermadhesin, CUB domain
  • 57424 - LDL receptor-like module
  • 56487 - SRCR-like
  • 0Direct
    88633,50494,52540
  • 88633 - Positive stranded ssRNA viruses
  • 50494 - Trypsin-like serine proteases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    81624,46946,57716
  • 81624 - N-terminal domain of MutM-like DNA repair proteins
  • 46946 - S13-like H2TH domain
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 0Direct
    57756,50630,56672
  • 57756 - Retrovirus zinc finger-like domains
  • 50630 - Acid proteases
  • 56672 - DNA/RNA polymerases
  • 0Direct
    81324,52799,49562
  • 81324 - Voltage-gated potassium channels
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 0Direct
    53067,53067,100920
  • 53067 - Actin-like ATPase domain
  • 53067 - Actin-like ATPase domain
  • 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
  • 0Direct
    51445,49303,74650
  • 51445 - (Trans)glycosidases
  • 49303 - beta-Galactosidase/glucuronidase domain
  • 74650 - Galactose mutarotase-like
  • 0Direct
    100895,56487,57424
  • 100895 - Kazal-type serine protease inhibitors
  • 56487 - SRCR-like
  • 57424 - LDL receptor-like module
  • 0Direct
    52540,46785,158702
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 46785 - "Winged helix" DNA-binding domain
  • 158702 - Sec63 N-terminal domain-like
  • 0Direct
    53098,51283,46919
  • 53098 - Ribonuclease H-like
  • 51283 - dUTPase-like
  • 46919 - N-terminal Zn binding domain of HIV integrase
  • 0Direct
    56672,46919,53098
  • 56672 - DNA/RNA polymerases
  • 46919 - N-terminal Zn binding domain of HIV integrase
  • 53098 - Ribonuclease H-like
  • 0Direct
    51445,51011,49265
  • 51445 - (Trans)glycosidases
  • 51011 - Glycosyl hydrolase domain
  • 49265 - Fibronectin type III
  • 0Direct
    50494,52540,56672
  • 50494 - Trypsin-like serine proteases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 56672 - DNA/RNA polymerases
  • 0Direct
    49854,57196,49854
  • 49854 - Spermadhesin, CUB domain
  • 57196 - EGF/Laminin
  • 49854 - Spermadhesin, CUB domain
  • 0Direct
    54211,54211,54637
  • 54211 - Ribosomal protein S5 domain 2-like
  • 54211 - Ribosomal protein S5 domain 2-like
  • 54637 - Thioesterase/thiol ester dehydrase-isomerase
  • 0Direct
    57424,57424,57424
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 0Direct
    49785,81296,48208
  • 49785 - Galactose-binding domain-like
  • 81296 - E set domains
  • 48208 - Six-hairpin glycosidases
  • 0Direct
    51278,51338,51556
  • 51278 - Urease, beta-subunit
  • 51338 - Composite domain of metallo-dependent hydrolases
  • 51556 - Metallo-dependent hydrolases
  • 0Direct
    54111,51278,51338
  • 54111 - Urease, gamma-subunit
  • 51278 - Urease, beta-subunit
  • 51338 - Composite domain of metallo-dependent hydrolases
  • 0Direct
    52799,56091,50249
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 56091 - DNA ligase/mRNA capping enzyme, catalytic domain
  • 50249 - Nucleic acid-binding proteins
  • 0Direct
    56568,47233,52799
  • 56568 - Non-globular alpha+beta subunits of globular proteins
  • 47233 - Bacterial GAP domain
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 0Direct
    49785,51445,49344
  • 49785 - Galactose-binding domain-like
  • 51445 - (Trans)glycosidases
  • 49344 - CBD9-like
  • 0Direct
    49503,110083,55909
  • 49503 - Cupredoxins
  • 110083 - Peptidylarginine deiminase Pad4, middle domain
  • 55909 - Pentein
  • 0Direct
    49854,49854,57424
  • 49854 - Spermadhesin, CUB domain
  • 49854 - Spermadhesin, CUB domain
  • 57424 - LDL receptor-like module
  • 0Direct
    49303,51445,49303
  • 49303 - beta-Galactosidase/glucuronidase domain
  • 51445 - (Trans)glycosidases
  • 49303 - beta-Galactosidase/glucuronidase domain
  • 0Direct
    57756,51283,50630
  • 57756 - Retrovirus zinc finger-like domains
  • 51283 - dUTPase-like
  • 50630 - Acid proteases
  • 0Direct
    57424,56487,50494
  • 57424 - LDL receptor-like module
  • 56487 - SRCR-like
  • 50494 - Trypsin-like serine proteases
  • 0Direct
    51445,49344,49344
  • 51445 - (Trans)glycosidases
  • 49344 - CBD9-like
  • 49344 - CBD9-like
  • 0Direct
    53067,53067,109604
  • 53067 - Actin-like ATPase domain
  • 53067 - Actin-like ATPase domain
  • 109604 - HD-domain/PDEase-like
  • 0Direct
    54637,54637,55961
  • 54637 - Thioesterase/thiol ester dehydrase-isomerase
  • 54637 - Thioesterase/thiol ester dehydrase-isomerase
  • 55961 - Bet v1-like
  • 0Direct
    52540,46785,47819
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 46785 - "Winged helix" DNA-binding domain
  • 47819 - HRDC-like
  • 0Direct
    49384,55545,51445
  • 49384 - Carbohydrate-binding domain
  • 55545 - beta-N-acetylhexosaminidase-like domain
  • 51445 - (Trans)glycosidases
  • 0Direct
    49785,49785,49785
  • 49785 - Galactose-binding domain-like
  • 49785 - Galactose-binding domain-like
  • 49785 - Galactose-binding domain-like
  • 0Direct
    52540,51294,55608
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 51294 - Hedgehog/intein (Hint) domain
  • 55608 - Homing endonucleases
  • 0Direct
    52540,52540,142877
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 142877 - EndoU-like
  • 0Direct
    50630,56672,46919
  • 50630 - Acid proteases
  • 56672 - DNA/RNA polymerases
  • 46919 - N-terminal Zn binding domain of HIV integrase
  • 0Direct
    88713,88688,74650
  • 88713 - Glycoside hydrolase/deacetylase
  • 88688 - Families 57/38 glycoside transferase middle domain
  • 74650 - Galactose mutarotase-like
  • 0.000000000116Direct
    52283,51735,52283
  • 52283 - Formate/glycerate dehydrogenase catalytic domain-like
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 52283 - Formate/glycerate dehydrogenase catalytic domain-like
  • 0.0000000007691Direct
    52540,52540,56672
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 56672 - DNA/RNA polymerases
  • 0.0000002465Direct
    48726,49265,49265
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 49265 - Fibronectin type III
  • 0.000003963Direct
    52335,51556,51338
  • 52335 - Methylglyoxal synthase-like
  • 51556 - Metallo-dependent hydrolases
  • 51338 - Composite domain of metallo-dependent hydrolases
  • 0.000006578Direct
    51445,51011,49452
  • 51445 - (Trans)glycosidases
  • 51011 - Glycosyl hydrolase domain
  • 49452 - Starch-binding domain-like
  • 0.00002953Direct
    51735,47336,53474
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 47336 - ACP-like
  • 53474 - alpha/beta-Hydrolases
  • 0.0001332Direct
    56059,52335,51556
  • 56059 - Glutathione synthetase ATP-binding domain-like
  • 52335 - Methylglyoxal synthase-like
  • 51556 - Metallo-dependent hydrolases
  • 0.0001841Direct
    54236,47031,50729
  • 54236 - Ubiquitin-like
  • 47031 - Second domain of FERM
  • 50729 - PH domain-like
  • 0.001064Inherited
    52540,52540,52540
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.002692Inherited
    52021,52317,52440
  • 52021 - Carbamoyl phosphate synthetase, small subunit N-terminal domain
  • 52317 - Class I glutamine amidotransferase-like
  • 52440 - PreATP-grasp domain
  • 0.005017Inherited
    52317,52440,56059
  • 52317 - Class I glutamine amidotransferase-like
  • 52440 - PreATP-grasp domain
  • 56059 - Glutathione synthetase ATP-binding domain-like
  • 0.005017Inherited
    48726,48726,49265
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 0.0175Inherited
    81296,51445,51011
  • 81296 - E set domains
  • 51445 - (Trans)glycosidases
  • 51011 - Glycosyl hydrolase domain
  • 0.1024Inherited
    109604,81301,81271
  • 109604 - HD-domain/PDEase-like
  • 81301 - Nucleotidyltransferase
  • 81271 - TGS-like
  • 0.1115Inherited
    50129,51735,51735
  • 50129 - GroES-like
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 0.1291Inherited
    51735,51735,47336
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 47336 - ACP-like
  • 0.7512Inherited
    52518,52467,52518
  • 52518 - Thiamin diphosphate-binding fold (THDP-binding)
  • 52467 - DHS-like NAD/FAD-binding domain
  • 52518 - Thiamin diphosphate-binding fold (THDP-binding)
  • 1Inherited
    48726,48726,48726
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 1Inherited
    52440,56059,48108
  • 52440 - PreATP-grasp domain
  • 56059 - Glutathione synthetase ATP-binding domain-like
  • 48108 - Carbamoyl phosphate synthetase, large subunit connection domain
  • 1Inherited
    52440,56059,52335
  • 52440 - PreATP-grasp domain
  • 56059 - Glutathione synthetase ATP-binding domain-like
  • 52335 - Methylglyoxal synthase-like
  • 1Inherited
    48108,52440,56059
  • 48108 - Carbamoyl phosphate synthetase, large subunit connection domain
  • 52440 - PreATP-grasp domain
  • 56059 - Glutathione synthetase ATP-binding domain-like
  • 1Inherited
    56059,48108,52440
  • 56059 - Glutathione synthetase ATP-binding domain-like
  • 48108 - Carbamoyl phosphate synthetase, large subunit connection domain
  • 52440 - PreATP-grasp domain
  • 1Inherited


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