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Enzyme Commission (EC): Acting on ester bonds

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Root: EC Hierarchy (from IntEnz release 70)

Shortest distance to current term (+ for parents, - for children) EC term [EC ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + 2:   root [root] <7>
+ 1:   Hydrolases [3] <13>(395|668) (394|418|206)
0:   Acting on ester bonds [3.1] <23>(156|225) (156|126|55)
- 1:   Phosphoric monoester hydrolases [3.1.3] <111>(60|78) (60|45|12)
- 1:   Carboxylic ester hydrolases [3.1.1] <108>(32|47) (32|13|0)
- 1:   Phosphoric diester hydrolases [3.1.4] <61>(31|30) (31|22|13)
- 1:   Site specific endodeoxyribonucleases: cleavage is sequence specific [3.1.23] <59>(0|0) (0|0|0)
- 1:   Thiolester hydrolases [3.1.2] <34>(16|19) (16|11|4)
- 1:   Sulfuric ester hydrolases [3.1.6] <20>(1|1) (1|0|0)
- 1:   Endoribonucleases producing 5'-phosphomonoesters [3.1.26] <15>(23|29) (23|21|20)
- 1:   Diphosphoric monoester hydrolases [3.1.7] <12>(6|4) (6|3|1)
- 1:   Endoribonucleases producing other than 5'-phosphomonoesters [3.1.27] <10>(1|2) (1|0|0)
- 1:   Endodeoxyribonucleases producing 5'-phosphomonoesters [3.1.21] <9>(6|4) (6|1|0)
- 1:   Exodeoxyribonucleases producing 5'-phosphomonoesters [3.1.11] <8>(11|8) (11|3|0)
- 1:   Endodeoxyribonucleases producing other than 5'-phosphomonoesters [3.1.22] <5>(3|4) (3|0|0)
- 1:   Exoribonucleases producing 5'-phosphomonoesters [3.1.13] <5>(19|19) (19|18|13)
- 1:   Site specific endodeoxyribonucleases: cleavage is not sequence specific [3.1.24] <4>(0|0) (0|0|0)
- 1:   Endoribonucleases active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoest [3.1.30] <2>(1|1) (1|0|0)
- 1:   Exodeoxyribonucleases producing 3'-phosphomonoesters [3.1.12] <2>(2|1) (2|1|0)
- 1:   Phosphoric triester hydrolases [3.1.8] <2>(1|1) (1|0|0)
- 1:   Site-specific endodeoxyribonucleases specific for altered bases [3.1.25] <2>(0|0) (0|0|0)
- 1:   Endoribonucleases active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoest [3.1.31] <1>(2|2) (2|3|3)
- 1:   Exonucleases active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters [3.1.16] <1>(0|0) (0|0|0)
- 1:   Exonucleases active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters [3.1.15] <1>(0|0) (0|0|0)
- 1:   Exoribonucleases producing 3'-phosphomonoesters [3.1.14] <1>(0|0) (0|0|0)
- 1:   Triphosphoric monoester hydrolases [3.1.5] <1>(1|1) (1|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
Phosphotyrosine protein phosphatases I0Direct
Rhodanese/Cell cycle control phosphatase0Direct
His-Me finger endonucleases0Direct
DNA-binding domain of retroviral integrase0Direct
Acid phosphatase/Vanadium-dependent haloperoxidase0Direct
Peptidyl-tRNA hydrolase II0Direct
ComB-like0Direct
PP2C-like0Direct
Bacterial GAP domain0Direct
Ribonuclease H-like0Direct
FabD/lysophospholipase-like0Direct
Xylose isomerase-like0Direct
Metallo-dependent phosphatases0Direct
L9 N-domain-like0Direct
CheY-like0Direct
AlbA-like0Direct
HD-domain/PDEase-like0Direct
RNase III domain-like0Direct
Outer membrane phospholipase A (OMPLA)0Direct
Phosphoglycerate mutase-like0Direct
SurE-like0Direct
Carbohydrate phosphatase0Direct
Toprim domain0Direct
GAF domain-like0Direct
dsRNA-binding domain-like0Direct
DNase I-like0Direct
Phospholipase C/P1 nuclease0Direct
Lipase/lipooxygenase domain (PLAT/LH2 domain)0Direct
EAL domain-like0Direct
Peptidyl-tRNA hydrolase domain-like0Direct
SGNH hydrolase0Direct
Somatomedin B domain0Direct
Retrovirus zinc finger-like domains0Direct
Peptidyl-tRNA hydrolase-like0Direct
(Phosphotyrosine protein) phosphatases II0Direct
Viral protein domain0Direct
HAD-like0Direct
Ribosomal protein S5 domain 2-like0Direct
Rnp2-like0Direct
Putative isomerase YbhE0Direct
Thermostable phytase (3-phytase)0Direct
Microbial ribonucleases0Direct
C2 domain (Calcium/lipid-binding domain, CaLB)0Direct
cAMP-binding domain-like0Direct
Rof/RNase P subunit-like0Direct
Retroviral matrix proteins0Direct
PH domain-like0Direct
PLC-like phosphodiesterases0Direct
PHP domain-like0Direct
N-terminal Zn binding domain of HIV integrase0Direct
Plant invertase/pectin methylesterase inhibitor0Direct
alpha/beta-Hydrolases0Direct
Purple acid phosphatase, N-terminal domain0Direct
CRAL/TRIO N-terminal domain0Direct
Retrovirus capsid protein, N-terminal core domain0Direct
Metallo-hydrolase/oxidoreductase0Direct
Methylesterase CheB, C-terminal domain0Direct
Retrovirus capsid dimerization domain-like0Direct
Phospholipase A2, PLA20Direct
DTD-like0Direct
Nitrous oxide reductase, N-terminal domain0Direct
Protein serine/threonine phosphatase 2C, C-terminal domain0Direct
Calcium-dependent phosphotriesterase0Direct
Staphylococcal nuclease0Direct
Phospholipase D/nuclease0Direct
Holliday junction resolvase RusA0Direct
PAZ domain0Direct
Voltage-gated potassium channels0Direct
C-terminal domain of PLC-beta0Direct
Influenza hemagglutinin (stalk)0Direct
AF0625-like0Direct
Sulfolobus fructose-1,6-bisphosphatase-like0Direct
XseB-like0Direct
DNA/RNA polymerases2.558e-16Direct
Alkaline phosphatase-like0.00000000000000151Direct
WD40 repeat-like0.000000000000002505Direct
LigT-like0.00000000000001697Direct
Fibronectin type III0.00000000000002936Direct
EF-hand0.000000000000528Direct
5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain0.0000000002828Direct
DEK C-terminal domain0.000000002721Direct
DNA clamp0.000000005264Direct
SMAD/FHA domain0.000000035Direct
PX domain0.0000001312Direct
Second domain of FERM0.0000002096Direct
L domain-like0.0000006344Direct
Thioesterase/thiol ester dehydrase-isomerase0.000001013Direct
SH2 domain0.000003701Direct
GTPase activation domain, GAP0.000005584Direct
Integrin alpha N-terminal domain0.000005584Direct
Ras GEF0.000007356Direct
Restriction endonuclease-like0.000007453Direct
Saposin0.000009708Direct
Immunoglobulin0.00005211Direct
Acid proteases0.00007079Direct
ssDNA viruses0.0001023Direct
Chaperone J-domain0.0002692Direct
C-terminal (heme d1) domain of cytochrome cd1-nitrite reductase0.000587Direct
CYTH-like phosphatases0.00108Inherited
NTF2-like0.002127Inherited
CRAL/TRIO domain0.002927Inherited
HRDC-like0.007244Inherited
Pectin lyase-like0.01518Inherited
RNA-binding domain, RBD0.01952Inherited
Kelch motif0.02322Inherited
Non-globular alpha+beta subunits of globular proteins0.02732Inherited
Ubiquitin-like0.07229Inherited
L30e-like0.0819Inherited
PIN domain-like0.08995Inherited
R3H domain0.1209Inherited
Probable ACP-binding domain of malonyl-CoA ACP transacylase0.2322Inherited
Methylated DNA-protein cysteine methyltransferase, C-terminal domain0.2379Inherited
Quinoprotein alcohol dehydrogenase-like0.2505Inherited
Bet v1-like0.2542Inherited
PYP-like sensor domain (PAS domain)0.3118Inherited
Autotransporter0.3304Inherited
Hedgehog/intein (Hint) domain0.3359Inherited
ACP-like0.3464Inherited
Carbonic anhydrase0.3941Inherited
Ankyrin repeat0.4295Inherited
SAM/Pointed domain0.4498Inherited
SH3-domain0.5014Inherited
FYVE/PHD zinc finger0.6573Inherited
TPR-like0.733Inherited
Starch-binding domain-like0.7701Inherited
Tudor/PWWP/MBT0.9732Inherited
HIT-like0.9769Inherited
Nucleic acid-binding proteins1Inherited
Inosine monophosphate dehydrogenase (IMPDH)1Inherited
UDP-Glycosyltransferase/glycogen phosphorylase1Inherited
NAD(P)-binding Rossmann-fold domains1Inherited
AraD/HMP-PK domain-like1Inherited
Glutaminase/Asparaginase1Inherited
ACT-like1Inherited
Thiolase-like1Inherited
Phosphoenolpyruvate/pyruvate domain1Inherited
PDZ domain-like1Inherited
Periplasmic binding protein-like II1Inherited
TGS-like1Inherited
Cysteine proteinases1Inherited
GroES-like1Inherited
ClpP/crotonase1Inherited
Concanavalin A-like lectins/glucanases1Inherited
Thioredoxin-like1Inherited
Glycoside hydrolase/deacetylase1Inherited
Nucleotide cyclase1Inherited
P-loop containing nucleoside triphosphate hydrolases1Inherited
NagB/RpiA/CoA transferase-like1Inherited
DHH phosphoesterases1Inherited
dUTPase-like1Inherited
Macro domain-like1Inherited
Nucleotidyltransferase1Inherited
Terpenoid cyclases/Protein prenyltransferases1Inherited
DNA ligase/mRNA capping enzyme, catalytic domain1Inherited
Terpenoid synthases1Inherited
S-adenosyl-L-methionine-dependent methyltransferases1Inherited


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Family

(show details)
SCOP termFDR (all)Annotation (direct or inherited)
Nitrous oxide reductase, N-terminal domain0Direct
Histidinol phosphatase-like0Direct
GAF domain0Direct
Lysophospholipase0Direct
RecU-like0Direct
Bacterial ribonucleases0Direct
GpdQ-like0Direct
Phosphotriesterase-like0Direct
Esterase domain of haemagglutinin-esterase-fusion glycoprotein HEF10Direct
PAZ domain0Direct
2',3'-cyclic nucleotide 3'-phosphodiesterase, catalytic domain0Direct
Cutinase-like0Direct
Thioesterases0Direct
NLI interacting factor-like phosphatase0Direct
RNase Z-like0Direct
Thermostable phytase (3-phytase)0Direct
2'-5' RNA ligase LigT0Direct
4HBT-like0Direct
Retroviral integrase, catalytic domain0Direct
Immunodeficiency virus matrix proteins0Direct
CRAL/TRIO domain0Direct
Pectin methylesterase0Direct
YihX-like0Direct
EAL domain0Direct
Alkaline phosphatase0Direct
Fungal ribonucleases0Direct
DTD-like0Direct
CRAL/TRIO N-terminal domain0Direct
Biotin biosynthesis protein BioH0Direct
RuvC resolvase0Direct
Phospholipase C0Direct
Ribonuclease H0Direct
Colipase-binding domain0Direct
GlpX-like bacterial fructose-1,6-bisphosphatase0Direct
HTLV-II matrix protein0Direct
Bacterial lipase0Direct
Esterase0Direct
Sphingomyelin phosphodiesterase-like0Direct
RNase III catalytic domain-like0Direct
PLC-like (P variant)0Direct
Retrovirus zinc finger-like domains0Direct
Inositol monophosphatase/fructose-1,6-bisphosphatase-like0Direct
Acyl-CoA thioesterase0Direct
tRNA splicing product Appr>p cyclic nucleotide phosphodiesterase0Direct
Purple acid phosphatase, N-terminal domain0Direct
Retrovirus capsid protein C-terminal domain0Direct
Putative isomerase YbhE0Direct
Protein serine/threonine phosphatase0Direct
Mammalian PLC0Direct
MMLV matrix protein-like0Direct
Cell cycle control phosphatase, catalytic domain0Direct
Glyoxalase II (hydroxyacylglutathione hydrolase)0Direct
Protein serine/threonine phosphatase 2C, C-terminal domain0Direct
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, phosphatase domain0Direct
Type 2 phosphatidic acid phosphatase, PAP20Direct
Histidine acid phosphatase0Direct
Glycerophosphoryl diester phosphodiesterase0Direct
RNB domain-like0Direct
PDEase0Direct
Arylsulfatase0Direct
Carboxylesterase0Direct
Peptidyl-tRNA hydrolase domain0Direct
Dual specificity phosphatase-like0Direct
RNase P subunit p29-like0Direct
Double-stranded RNA-binding domain (dsRBD)0Direct
CAF1-like ribonuclease0Direct
Influenza hemagglutinin (stalk)0Direct
Peptidyl-tRNA hydrolase II0Direct
PP2C-like0Direct
GAG polyprotein M-domain0Direct
beta-Phosphoglucomutase-like0Direct
Toprim domain0Direct
Pyrimidine 5'-nucleotidase (UMPH-1)0Direct
Exodeoxyribonuclease V beta chain (RecC), C-terminal domain0Direct
Hypothetical esterase YJL068C0Direct
Purple acid phosphatase-like0Direct
Hjc-like0Direct
Retroviral protease (retropepsin)0Direct
ComB-like0Direct
Insect phospholipase A20Direct
AF0625-like0Direct
Methylesterase CheB, C-terminal domain0Direct
Gastric lipase0Direct
Inositol polyphosphate 5-phosphatase (IPP5)0Direct
Enolase-phosphatase E10Direct
Acyl-ACP thioesterase-like0Direct
Dienelactone hydrolase0Direct
GRAM domain0Direct
Alpha-toxin, C-terminal domain0Direct
Myotubularin-like phosphatases0Direct
Class B acid phosphatase, AphA0Direct
Virulence effector SptP domain0Direct
5' nucleotidase-like0Direct
Higher-molecular-weight phosphotyrosine protein phosphatases0Direct
N-terminal Zn binding domain of HIV integrase0Direct
cAMP-binding domain0Direct
Retrovirus capsid protein, N-terminal core domain0Direct
Sulfolobus fructose-1,6-bisphosphatase-like0Direct
Integrin alpha N-terminal domain0Direct
Bacterial GAP domain0Direct
Putative acetylxylan esterase-like0Direct
Parvoviridae-like VP0Direct
Endonuclease I0Direct
L30e/L7ae ribosomal proteins0Direct
mRNA triphosphatase CET10Direct
Serum paraoxonase/arylesterase 1, PON10Direct
Phosphoserine phosphatase0Direct
XseB-like0Direct
Holliday junction resolvase RusA0Direct
Staphylococcal nuclease0Direct
Fungal lipases0Direct
Vertebrate phospholipase A20Direct
RNase P protein0Direct
Pancreatic lipase, N-terminal domain0Direct
Hemagglutinin domain of haemagglutinin-esterase-fusion glycoprotein HEF10Direct
SGL-like0Direct
TAP-like0Direct
SurE-like0Direct
Outer membrane phospholipase A (OMPLA)0Direct
EF-hand modules in multidomain proteins0Direct
CheY-related0Direct
N-terminal domain of RNase HI0Direct
RNase P subunit p300Direct
Reverse transcriptase0Direct
C-terminal domain of PLC-beta0Direct
DNA/RNA non-specific endonuclease0Direct
Rpp14/Pop5-like0Direct
DnaQ-like 3'-5' exonuclease0Direct
Patatin0Direct
Low-molecular-weight phosphotyrosine protein phosphatases0Direct
MtnX-like0Direct
Magnesium-dependent phosphatase-1, Mdp10Direct
Somatomedin B domain0Direct
Predicted hydrolases Cof0Direct
Plant invertase/pectin methylesterase inhibitor0Direct
RNase D C-terminal domains0Direct
Nuclease0Direct
P1 nuclease0Direct
HD domain0Direct
Acetylcholinesterase-like0Direct
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, kinase domain0Direct
DNA-binding domain of retroviral integrase0Direct
Peptidyl-tRNA hydrolase-like0Direct
Trehalose-phosphatase0Direct
Endonuclease IV0Direct
Fibronectin type III0.000000000000004349Direct
Acetylhydrolase0.00000000001253Direct
Pleckstrin-homology domain (PH domain)0.00000000001501Direct
Cold shock DNA-binding domain-like0.00000000002255Direct
5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain0.0000000001016Direct
5'-nucleotidase (syn. UDP-sugar hydrolase), N-terminal domain0.0000000001016Direct
DNase I-like0.0000000001855Direct
Third domain of FERM0.0000000003794Direct
phosphatase domain of polynucleotide kinase0.000000003439Direct
First domain of FERM0.00000002772Direct
FHA domain0.00000005409Direct
Second domain of FERM0.00000008629Direct
DEK C-terminal domain0.00000037Direct
Acyl-carrier protein (ACP)0.00000037Direct
I set domains0.0000004832Direct
Probable phosphatase YrbI0.0000008382Direct
PaaI/YdiI-like0.0000009383Direct
Imidazole glycerol phosphate dehydratase0.000001108Direct
SH2 domain0.000001671Direct
PHP domain0.000003144Direct
BCR-homology GTPase activation domain (BH-domain)0.000003884Direct
PX domain0.000004169Direct
NagD-like0.000005147Direct
Ras GEF0.000005233Direct
RelA/SpoT domain0.00000779Direct
Thioesterase domain of polypeptide, polyketide and fatty acid synthases0.00001313Direct
Canonical RBD0.0000178Direct
CoA transferase alpha subunit-like0.00002834Direct
Leucine rich effector protein YopM0.00003545Direct
PDZ domain0.00003953Direct
Hydroxynitrile lyase-like0.0000718Direct
FYVE, a phosphatidylinositol-3-phosphate binding domain0.0001062Direct
Chaperone J-domain0.0002026Direct
MaoC-like0.0002325Direct
FabD-like0.0004003Direct
PP1699/LP2961-like0.0007389Direct
Haloperoxidase0.0008419Direct
mRNA capping enzyme0.001087Inherited
Mason-Pfizer monkey virus matrix protein0.01433Inherited
MAM domain0.01563Inherited
HpcH/HpaI aldolase0.02666Inherited
mRNA cap (Guanine N-7) methyltransferase0.02932Inherited
WD40-repeat0.0365Inherited
Ras-binding domain, RBD0.05413Inherited
GGDEF domain0.06645Inherited
5' to 3' exonuclease catalytic domain0.07315Inherited
Ubiquitin-related0.08661Inherited
R3H domain0.09163Inherited
Macro domain0.09883Inherited
Tetratricopeptide repeat (TPR)0.1828Inherited
SAM (sterile alpha motif) domain0.1958Inherited
Methylated DNA-protein cysteine methyltransferase, C-terminal domain0.2015Inherited
Probable ACP-binding domain of malonyl-CoA ACP transacylase0.2355Inherited
Tudor domain0.2779Inherited
Carbonic anhydrase0.33Inherited
Ankyrin repeat0.3474Inherited
Trehalose-6-phosphate synthase, OtsA0.3595Inherited
DNA polymerase I0.3611Inherited
Starch-binding domain0.3816Inherited
SH3-domain0.4334Inherited
Glucose 6-phosphate dehydrogenase-like0.8364Inherited
Crotonase-like0.8385Inherited
Epoxide hydrolase0.9155Inherited
AraD-like aldolase/epimerase0.9274Inherited
Carbon-carbon bond hydrolase0.9773Inherited
Cofactor-dependent phosphoglycerate mutase0.9858Inherited
Tandem AAA-ATPase domain1Inherited
Terpenoid cyclase C-terminal domain1Inherited
Terpenoid cyclase N-terminal domain1Inherited
Tyrosine-dependent oxidoreductases1Inherited
dUTPase-like1Inherited
Glutaminase/Asparaginase1Inherited
Glutathione peroxidase-like1Inherited
Exodeoxyribonuclease V beta chain (RecB), C-terminal domain1Inherited
NagB-like1Inherited
Phosphate binding protein-like1Inherited
Thiolase-related1Inherited
Nucleotide and nucleoside kinases1Inherited
Alcohol dehydrogenase-like, C-terminal domain1Inherited
Alcohol dehydrogenase-like, N-terminal domain1Inherited


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Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
XseB-like0Direct
(Phosphotyrosine protein) phosphatases II0Direct
Influenza hemagglutinin (stalk)0Direct
alpha/beta-Hydrolases0Direct
Holliday junction resolvase RusA0Direct
AlbA-like0Direct
HAD-like0Direct
AF0625-like0Direct
Ribonuclease H-like0Direct
DNA-binding domain of retroviral integrase0Direct
CheY-like0Direct
Metallo-hydrolase/oxidoreductase0Direct
Plant invertase/pectin methylesterase inhibitor0Direct
ComB-like0Direct
PAZ domain0Direct
Retrovirus capsid protein, N-terminal core domain0Direct
Carbohydrate phosphatase0Direct
Phospholipase A2, PLA20Direct
Microbial ribonucleases0Direct
Staphylococcal nuclease0Direct
Rhodanese/Cell cycle control phosphatase0Direct
EAL domain-like0Direct
Peptidyl-tRNA hydrolase II0Direct
SGNH hydrolase0Direct
Retrovirus zinc finger-like domains0Direct
Retrovirus capsid dimerization domain-like0Direct
cAMP-binding domain-like0Direct
Peptidyl-tRNA hydrolase-like0Direct
PLC-like phosphodiesterases0Direct
Rof/RNase P subunit-like0Direct
Lipase/lipooxygenase domain (PLAT/LH2 domain)0Direct
DNase I-like0Direct
Rnp2-like0Direct
Bacterial GAP domain0Direct
Phospholipase C/P1 nuclease0Direct
PH domain-like0Direct
SurE-like0Direct
L9 N-domain-like0Direct
Voltage-gated potassium channels0Direct
Retroviral matrix proteins0Direct
Viral protein domain0Direct
Methylesterase CheB, C-terminal domain0Direct
N-terminal Zn binding domain of HIV integrase0Direct
Ribosomal protein S5 domain 2-like0Direct
RNase III domain-like0Direct
Xylose isomerase-like0Direct
Outer membrane phospholipase A (OMPLA)0Direct
Purple acid phosphatase, N-terminal domain0Direct
Nitrous oxide reductase, N-terminal domain0Direct
His-Me finger endonucleases0Direct
Putative isomerase YbhE0Direct
DTD-like0Direct
Protein serine/threonine phosphatase 2C, C-terminal domain0Direct
dsRNA-binding domain-like0Direct
FabD/lysophospholipase-like0Direct
Calcium-dependent phosphotriesterase0Direct
Phospholipase D/nuclease0Direct
Phosphoglycerate mutase-like0Direct
CRAL/TRIO N-terminal domain0Direct
C2 domain (Calcium/lipid-binding domain, CaLB)0Direct
GAF domain-like0Direct
Phosphotyrosine protein phosphatases I0Direct
Thermostable phytase (3-phytase)0Direct
Metallo-dependent phosphatases0Direct
HD-domain/PDEase-like0Direct
Sulfolobus fructose-1,6-bisphosphatase-like0Direct
PP2C-like0Direct
C-terminal domain of PLC-beta0Direct
Peptidyl-tRNA hydrolase domain-like0Direct
Toprim domain0Direct
Somatomedin B domain0Direct
PHP domain-like0Direct
Acid phosphatase/Vanadium-dependent haloperoxidase0Direct
DNA/RNA polymerases1.776e-16Direct
Alkaline phosphatase-like0.000000000000001056Direct
WD40 repeat-like0.000000000000001756Direct
LigT-like0.00000000000001198Direct
Fibronectin type III0.00000000000002077Direct
EF-hand0.0000000000003784Direct
5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain0.0000000002094Direct
DEK C-terminal domain0.000000002042Direct
DNA clamp0.000000003966Direct
SMAD/FHA domain0.00000002663Direct
PX domain0.0000001007Direct
Second domain of FERM0.0000001614Direct
L domain-like0.0000004933Direct
Thioesterase/thiol ester dehydrase-isomerase0.0000007907Direct
SH2 domain0.000002913Direct
Integrin alpha N-terminal domain0.000004398Direct
GTPase activation domain, GAP0.000004398Direct
Ras GEF0.000005804Direct
Restriction endonuclease-like0.000005882Direct
Saposin0.00000769Direct
Immunoglobulin0.00004182Direct
Acid proteases0.00005696Direct
ssDNA viruses0.00008268Direct
Chaperone J-domain0.0002193Direct
C-terminal (heme d1) domain of cytochrome cd1-nitrite reductase0.0004821Direct
CYTH-like phosphatases0.0008932Direct
NTF2-like0.001772Inherited
CRAL/TRIO domain0.002446Inherited
HRDC-like0.006112Inherited
Pectin lyase-like0.01294Inherited
RNA-binding domain, RBD0.01669Inherited
Kelch motif0.01989Inherited
Non-globular alpha+beta subunits of globular proteins0.02344Inherited
Ubiquitin-like0.06287Inherited
L30e-like0.07135Inherited
PIN domain-like0.07844Inherited
R3H domain0.106Inherited
Probable ACP-binding domain of malonyl-CoA ACP transacylase0.2069Inherited
Methylated DNA-protein cysteine methyltransferase, C-terminal domain0.2123Inherited
Quinoprotein alcohol dehydrogenase-like0.2238Inherited
Bet v1-like0.2272Inherited
PYP-like sensor domain (PAS domain)0.2817Inherited
Autotransporter0.2985Inherited
Hedgehog/intein (Hint) domain0.3035Inherited
ACP-like0.3133Inherited
Carbonic anhydrase0.3573Inherited
Ankyrin repeat0.3905Inherited
SAM/Pointed domain0.4097Inherited
SH3-domain0.4583Inherited
FYVE/PHD zinc finger0.6039Inherited
TPR-like0.6744Inherited
Starch-binding domain-like0.7091Inherited
Tudor/PWWP/MBT0.9007Inherited
HIT-like0.9042Inherited
AraD/HMP-PK domain-like0.9454Inherited
Glutaminase/Asparaginase1Inherited
Nucleotidyltransferase1Inherited
ACT-like1Inherited
Inosine monophosphate dehydrogenase (IMPDH)1Inherited
GroES-like1Inherited
Thioredoxin-like1Inherited
ClpP/crotonase1Inherited
Glycoside hydrolase/deacetylase1Inherited
TGS-like1Inherited
Nucleotide cyclase1Inherited
Nucleic acid-binding proteins1Inherited
Concanavalin A-like lectins/glucanases1Inherited
Phosphoenolpyruvate/pyruvate domain1Inherited
P-loop containing nucleoside triphosphate hydrolases1Inherited
Thiolase-like1Inherited
S-adenosyl-L-methionine-dependent methyltransferases1Inherited
NAD(P)-binding Rossmann-fold domains1Inherited
UDP-Glycosyltransferase/glycogen phosphorylase1Inherited
PDZ domain-like1Inherited
Terpenoid synthases1Inherited
Macro domain-like1Inherited
Cysteine proteinases1Inherited
dUTPase-like1Inherited
NagB/RpiA/CoA transferase-like1Inherited
DNA ligase/mRNA capping enzyme, catalytic domain1Inherited
Periplasmic binding protein-like II1Inherited
DHH phosphoesterases1Inherited
Terpenoid cyclases/Protein prenyltransferases1Inherited

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
101908,56219
  • 101908 - Putative isomerase YbhE
  • 56219 - DNase I-like
  • 0Direct
    52266,103515
  • 52266 - SGNH hydrolase
  • 103515 - Autotransporter
  • 0Direct
    56784,56784
  • 56784 - HAD-like
  • 56784 - HAD-like
  • 0Direct
    52058,56219
  • 52058 - L domain-like
  • 56219 - DNase I-like
  • 0Direct
    47353,57756
  • 47353 - Retrovirus capsid dimerization domain-like
  • 57756 - Retrovirus zinc finger-like domains
  • 0Direct
    55781,55781
  • 55781 - GAF domain-like
  • 55781 - GAF domain-like
  • 0Direct
    56300,47473
  • 56300 - Metallo-dependent phosphatases
  • 47473 - EF-hand
  • 0Direct
    55658,53098
  • 55658 - L9 N-domain-like
  • 53098 - Ribonuclease H-like
  • 0Direct
    55550,52799
  • 55550 - SH2 domain
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 0Direct
    47819,47819
  • 47819 - HRDC-like
  • 47819 - HRDC-like
  • 0Direct
    47836,47943
  • 47836 - Retroviral matrix proteins
  • 47943 - Retrovirus capsid protein, N-terminal core domain
  • 0Direct
    56300,56300
  • 56300 - Metallo-dependent phosphatases
  • 56300 - Metallo-dependent phosphatases
  • 0Direct
    56784,54427
  • 56784 - HAD-like
  • 54427 - NTF2-like
  • 0Direct
    49562,56024
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 56024 - Phospholipase D/nuclease
  • 0Direct
    56784,52540
  • 56784 - HAD-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    53474,49723
  • 53474 - alpha/beta-Hydrolases
  • 49723 - Lipase/lipooxygenase domain (PLAT/LH2 domain)
  • 0Direct
    49899,48726
  • 49899 - Concanavalin A-like lectins/glucanases
  • 48726 - Immunoglobulin
  • 0Direct
    56784,54211
  • 56784 - HAD-like
  • 54211 - Ribosomal protein S5 domain 2-like
  • 0Direct
    56672,46919
  • 56672 - DNA/RNA polymerases
  • 46919 - N-terminal Zn binding domain of HIV integrase
  • 0Direct
    54236,56784
  • 54236 - Ubiquitin-like
  • 56784 - HAD-like
  • 0Direct
    52540,55144
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 55144 - LigT-like
  • 0Direct
    46938,52087
  • 46938 - CRAL/TRIO N-terminal domain
  • 52087 - CRAL/TRIO domain
  • 0Direct
    50249,50249
  • 50249 - Nucleic acid-binding proteins
  • 50249 - Nucleic acid-binding proteins
  • 0Direct
    56672,53098
  • 56672 - DNA/RNA polymerases
  • 53098 - Ribonuclease H-like
  • 0Direct
    54637,52151
  • 54637 - Thioesterase/thiol ester dehydrase-isomerase
  • 52151 - FabD/lysophospholipase-like
  • 0Direct
    50249,56300
  • 50249 - Nucleic acid-binding proteins
  • 56300 - Metallo-dependent phosphatases
  • 0Direct
    53098,51283
  • 53098 - Ribonuclease H-like
  • 51283 - dUTPase-like
  • 0Direct
    51206,51206
  • 51206 - cAMP-binding domain-like
  • 51206 - cAMP-binding domain-like
  • 0Direct
    49562,54236
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 54236 - Ubiquitin-like
  • 0Direct
    51695,49562
  • 51695 - PLC-like phosphodiesterases
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 0Direct
    51283,46919
  • 51283 - dUTPase-like
  • 46919 - N-terminal Zn binding domain of HIV integrase
  • 0Direct
    48403,52151
  • 48403 - Ankyrin repeat
  • 52151 - FabD/lysophospholipase-like
  • 0Direct
    109715,52799
  • 109715 - DEK C-terminal domain
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 0Direct
    51695,51695
  • 51695 - PLC-like phosphodiesterases
  • 51695 - PLC-like phosphodiesterases
  • 0Direct
    49562,52151
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 52151 - FabD/lysophospholipase-like
  • 0Direct
    52821,52799
  • 52821 - Rhodanese/Cell cycle control phosphatase
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 0Direct
    47233,52799
  • 47233 - Bacterial GAP domain
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 0Direct
    55550,55550
  • 55550 - SH2 domain
  • 55550 - SH2 domain
  • 0Direct
    53098,54928
  • 53098 - Ribonuclease H-like
  • 54928 - RNA-binding domain, RBD
  • 0Direct
    54637,55961
  • 54637 - Thioesterase/thiol ester dehydrase-isomerase
  • 55961 - Bet v1-like
  • 0Direct
    53098,47819
  • 53098 - Ribonuclease H-like
  • 47819 - HRDC-like
  • 0Direct
    55781,109604
  • 55781 - GAF domain-like
  • 109604 - HD-domain/PDEase-like
  • 0Direct
    101690,53098
  • 101690 - PAZ domain
  • 53098 - Ribonuclease H-like
  • 0Direct
    49452,52799
  • 49452 - Starch-binding domain-like
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 0Direct
    49879,54197
  • 49879 - SMAD/FHA domain
  • 54197 - HIT-like
  • 0Direct
    49363,56300
  • 49363 - Purple acid phosphatase, N-terminal domain
  • 56300 - Metallo-dependent phosphatases
  • 0Direct
    69065,54768
  • 69065 - RNase III domain-like
  • 54768 - dsRNA-binding domain-like
  • 0Direct
    81606,81601
  • 81606 - PP2C-like
  • 81601 - Protein serine/threonine phosphatase 2C, C-terminal domain
  • 0Direct
    52266,49818
  • 52266 - SGNH hydrolase
  • 49818 - Viral protein domain
  • 0Direct
    69065,69065
  • 69065 - RNase III domain-like
  • 69065 - RNase III domain-like
  • 0Direct
    50729,56024
  • 50729 - PH domain-like
  • 56024 - Phospholipase D/nuclease
  • 0Direct
    52799,56091
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 56091 - DNA ligase/mRNA capping enzyme, catalytic domain
  • 0Direct
    54001,53098
  • 54001 - Cysteine proteinases
  • 53098 - Ribonuclease H-like
  • 0Direct
    52540,53254
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 53254 - Phosphoglycerate mutase-like
  • 0Direct
    55154,56091
  • 55154 - CYTH-like phosphatases
  • 56091 - DNA ligase/mRNA capping enzyme, catalytic domain
  • 0Direct
    50199,63748
  • 50199 - Staphylococcal nuclease
  • 63748 - Tudor/PWWP/MBT
  • 0Direct
    46919,53098
  • 46919 - N-terminal Zn binding domain of HIV integrase
  • 53098 - Ribonuclease H-like
  • 0Direct
    50044,51695
  • 50044 - SH3-domain
  • 51695 - PLC-like phosphodiesterases
  • 0Direct
    50729,47473
  • 50729 - PH domain-like
  • 47473 - EF-hand
  • 0Direct
    82708,53098
  • 82708 - R3H domain
  • 53098 - Ribonuclease H-like
  • 0Direct
    47473,51695
  • 47473 - EF-hand
  • 51695 - PLC-like phosphodiesterases
  • 0Direct
    51069,49265
  • 51069 - Carbonic anhydrase
  • 49265 - Fibronectin type III
  • 0Direct
    53098,46919
  • 53098 - Ribonuclease H-like
  • 46919 - N-terminal Zn binding domain of HIV integrase
  • 0Direct
    53649,54060
  • 53649 - Alkaline phosphatase-like
  • 54060 - His-Me finger endonucleases
  • 0Direct
    56784,53474
  • 56784 - HAD-like
  • 53474 - alpha/beta-Hydrolases
  • 0Direct
    56568,47233
  • 56568 - Non-globular alpha+beta subunits of globular proteins
  • 47233 - Bacterial GAP domain
  • 0Direct
    90188,90188
  • 90188 - Somatomedin B domain
  • 90188 - Somatomedin B domain
  • 0Direct
    49265,49265
  • 49265 - Fibronectin type III
  • 49265 - Fibronectin type III
  • 0Direct
    53098,53098
  • 53098 - Ribonuclease H-like
  • 53098 - Ribonuclease H-like
  • 0Direct
    47943,47353
  • 47943 - Retrovirus capsid protein, N-terminal core domain
  • 47353 - Retrovirus capsid dimerization domain-like
  • 0Direct
    50729,52799
  • 50729 - PH domain-like
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 0Direct
    50156,52799
  • 50156 - PDZ domain-like
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 0Direct
    55550,50044
  • 55550 - SH2 domain
  • 50044 - SH3-domain
  • 0Direct
    50974,50974
  • 50974 - Nitrous oxide reductase, N-terminal domain
  • 50974 - Nitrous oxide reductase, N-terminal domain
  • 0Direct
    50199,50199
  • 50199 - Staphylococcal nuclease
  • 50199 - Staphylococcal nuclease
  • 0Direct
    52172,52738
  • 52172 - CheY-like
  • 52738 - Methylesterase CheB, C-terminal domain
  • 0Direct
    90188,53649
  • 90188 - Somatomedin B domain
  • 53649 - Alkaline phosphatase-like
  • 0Direct
    52799,52799
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 0Direct
    56219,56219
  • 56219 - DNase I-like
  • 56219 - DNase I-like
  • 0Direct
    53098,50122
  • 53098 - Ribonuclease H-like
  • 50122 - DNA-binding domain of retroviral integrase
  • 0Direct
    50630,56672
  • 50630 - Acid proteases
  • 56672 - DNA/RNA polymerases
  • 0Direct
    57756,50630
  • 57756 - Retrovirus zinc finger-like domains
  • 50630 - Acid proteases
  • 0Direct
    53639,56784
  • 53639 - AraD/HMP-PK domain-like
  • 56784 - HAD-like
  • 0Direct
    48452,56300
  • 48452 - TPR-like
  • 56300 - Metallo-dependent phosphatases
  • 0Direct
    101148,51126
  • 101148 - Plant invertase/pectin methylesterase inhibitor
  • 51126 - Pectin lyase-like
  • 0Direct
    52151,51412
  • 52151 - FabD/lysophospholipase-like
  • 51412 - Inosine monophosphate dehydrogenase (IMPDH)
  • 0Direct
    81324,52799
  • 81324 - Voltage-gated potassium channels
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 0Direct
    52151,52151
  • 52151 - FabD/lysophospholipase-like
  • 52151 - FabD/lysophospholipase-like
  • 0Direct
    56219,54928
  • 56219 - DNase I-like
  • 54928 - RNA-binding domain, RBD
  • 0Direct
    52087,52799
  • 52087 - CRAL/TRIO domain
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 0Direct
    48537,49723
  • 48537 - Phospholipase C/P1 nuclease
  • 49723 - Lipase/lipooxygenase domain (PLAT/LH2 domain)
  • 0Direct
    48726,49265
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 0.000000000000001756Direct
    54637,54637
  • 54637 - Thioesterase/thiol ester dehydrase-isomerase
  • 54637 - Thioesterase/thiol ester dehydrase-isomerase
  • 0.000000000000002978Direct
    52799,49562
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 0.00000000000001922Direct
    64268,50729
  • 64268 - PX domain
  • 50729 - PH domain-like
  • 0.00000000001506Direct
    53474,53474
  • 53474 - alpha/beta-Hydrolases
  • 53474 - alpha/beta-Hydrolases
  • 0.00000000005148Direct
    56300,55816
  • 56300 - Metallo-dependent phosphatases
  • 55816 - 5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain
  • 0.0000000002094Direct
    54236,47031
  • 54236 - Ubiquitin-like
  • 47031 - Second domain of FERM
  • 0.000000000496Direct
    55073,141868
  • 55073 - Nucleotide cyclase
  • 141868 - EAL domain-like
  • 0.000000003966Direct
    47031,50729
  • 47031 - Second domain of FERM
  • 50729 - PH domain-like
  • 0.0000000135Direct
    63748,50199
  • 63748 - Tudor/PWWP/MBT
  • 50199 - Staphylococcal nuclease
  • 0.00000002946Direct
    56024,56024
  • 56024 - Phospholipase D/nuclease
  • 56024 - Phospholipase D/nuclease
  • 0.00000006351Direct
    100950,100950
  • 100950 - NagB/RpiA/CoA transferase-like
  • 100950 - NagB/RpiA/CoA transferase-like
  • 0.0000009104Direct
    81301,81271
  • 81301 - Nucleotidyltransferase
  • 81271 - TGS-like
  • 0.000005508Direct
    109604,81301
  • 109604 - HD-domain/PDEase-like
  • 81301 - Nucleotidyltransferase
  • 0.000005775Direct
    47336,53474
  • 47336 - ACP-like
  • 53474 - alpha/beta-Hydrolases
  • 0.00001032Direct
    53335,52949
  • 53335 - S-adenosyl-L-methionine-dependent methyltransferases
  • 52949 - Macro domain-like
  • 0.00008268Direct
    53474,53335
  • 53474 - alpha/beta-Hydrolases
  • 53335 - S-adenosyl-L-methionine-dependent methyltransferases
  • 0.0002193Direct
    53756,56784
  • 53756 - UDP-Glycosyltransferase/glycogen phosphorylase
  • 56784 - HAD-like
  • 0.001826Inherited
    54236,54236
  • 54236 - Ubiquitin-like
  • 54236 - Ubiquitin-like
  • 0.002446Inherited
    53774,48403
  • 53774 - Glutaminase/Asparaginase
  • 48403 - Ankyrin repeat
  • 0.009549Inherited
    51735,51735
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 0.01221Inherited
    57756,51283
  • 57756 - Retrovirus zinc finger-like domains
  • 51283 - dUTPase-like
  • 0.01783Inherited
    51283,50630
  • 51283 - dUTPase-like
  • 50630 - Acid proteases
  • 0.01783Inherited
    51735,47336
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 47336 - ACP-like
  • 0.02241Inherited
    52058,52058
  • 52058 - L domain-like
  • 52058 - L domain-like
  • 0.02792Inherited
    48726,48726
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 0.05127Inherited
    57756,57756
  • 57756 - Retrovirus zinc finger-like domains
  • 57756 - Retrovirus zinc finger-like domains
  • 0.1333Inherited
    53098,56672
  • 53098 - Ribonuclease H-like
  • 56672 - DNA/RNA polymerases
  • 0.163Inherited
    52151,55048
  • 52151 - FabD/lysophospholipase-like
  • 55048 - Probable ACP-binding domain of malonyl-CoA ACP transacylase
  • 0.2069Inherited
    50129,51735
  • 50129 - GroES-like
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 1Inherited
    54211,54211
  • 54211 - Ribosomal protein S5 domain 2-like
  • 54211 - Ribosomal protein S5 domain 2-like
  • 1Inherited
    48239,48576
  • 48239 - Terpenoid cyclases/Protein prenyltransferases
  • 48576 - Terpenoid synthases
  • 1Inherited
    52540,52540
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 1Inherited
    56091,50249
  • 56091 - DNA ligase/mRNA capping enzyme, catalytic domain
  • 50249 - Nucleic acid-binding proteins
  • 1Inherited
    53901,53901
  • 53901 - Thiolase-like
  • 53901 - Thiolase-like
  • 1Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    56672,53098,53098
  • 56672 - DNA/RNA polymerases
  • 53098 - Ribonuclease H-like
  • 53098 - Ribonuclease H-like
  • 0Direct
    46919,53098,50122
  • 46919 - N-terminal Zn binding domain of HIV integrase
  • 53098 - Ribonuclease H-like
  • 50122 - DNA-binding domain of retroviral integrase
  • 0Direct
    50729,47473,51695
  • 50729 - PH domain-like
  • 47473 - EF-hand
  • 51695 - PLC-like phosphodiesterases
  • 0Direct
    53098,46919,53098
  • 53098 - Ribonuclease H-like
  • 46919 - N-terminal Zn binding domain of HIV integrase
  • 53098 - Ribonuclease H-like
  • 0Direct
    47473,51695,49562
  • 47473 - EF-hand
  • 51695 - PLC-like phosphodiesterases
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 0Direct
    55550,50044,51695
  • 55550 - SH2 domain
  • 50044 - SH3-domain
  • 51695 - PLC-like phosphodiesterases
  • 0Direct
    50044,51695,49562
  • 50044 - SH3-domain
  • 51695 - PLC-like phosphodiesterases
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 0Direct
    69065,69065,54768
  • 69065 - RNase III domain-like
  • 69065 - RNase III domain-like
  • 54768 - dsRNA-binding domain-like
  • 0Direct
    56024,56024,56024
  • 56024 - Phospholipase D/nuclease
  • 56024 - Phospholipase D/nuclease
  • 56024 - Phospholipase D/nuclease
  • 0Direct
    50199,50199,50199
  • 50199 - Staphylococcal nuclease
  • 50199 - Staphylococcal nuclease
  • 50199 - Staphylococcal nuclease
  • 0Direct
    50729,56024,56024
  • 50729 - PH domain-like
  • 56024 - Phospholipase D/nuclease
  • 56024 - Phospholipase D/nuclease
  • 0Direct
    47836,47943,47353
  • 47836 - Retroviral matrix proteins
  • 47943 - Retrovirus capsid protein, N-terminal core domain
  • 47353 - Retrovirus capsid dimerization domain-like
  • 0Direct
    55781,55781,109604
  • 55781 - GAF domain-like
  • 55781 - GAF domain-like
  • 109604 - HD-domain/PDEase-like
  • 0Direct
    55781,55781,55781
  • 55781 - GAF domain-like
  • 55781 - GAF domain-like
  • 55781 - GAF domain-like
  • 0Direct
    56672,53098,50122
  • 56672 - DNA/RNA polymerases
  • 53098 - Ribonuclease H-like
  • 50122 - DNA-binding domain of retroviral integrase
  • 0Direct
    51283,46919,53098
  • 51283 - dUTPase-like
  • 46919 - N-terminal Zn binding domain of HIV integrase
  • 53098 - Ribonuclease H-like
  • 0Direct
    90188,53649,54060
  • 90188 - Somatomedin B domain
  • 53649 - Alkaline phosphatase-like
  • 54060 - His-Me finger endonucleases
  • 0Direct
    53098,51283,46919
  • 53098 - Ribonuclease H-like
  • 51283 - dUTPase-like
  • 46919 - N-terminal Zn binding domain of HIV integrase
  • 0Direct
    52799,56091,50249
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 56091 - DNA ligase/mRNA capping enzyme, catalytic domain
  • 50249 - Nucleic acid-binding proteins
  • 0Direct
    49899,48726,49265
  • 49899 - Concanavalin A-like lectins/glucanases
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 0Direct
    50630,56672,53098
  • 50630 - Acid proteases
  • 56672 - DNA/RNA polymerases
  • 53098 - Ribonuclease H-like
  • 0Direct
    50199,50199,63748
  • 50199 - Staphylococcal nuclease
  • 50199 - Staphylococcal nuclease
  • 63748 - Tudor/PWWP/MBT
  • 0Direct
    47353,57756,50630
  • 47353 - Retrovirus capsid dimerization domain-like
  • 57756 - Retrovirus zinc finger-like domains
  • 50630 - Acid proteases
  • 0Direct
    50199,63748,50199
  • 50199 - Staphylococcal nuclease
  • 63748 - Tudor/PWWP/MBT
  • 50199 - Staphylococcal nuclease
  • 0Direct
    53098,47819,47819
  • 53098 - Ribonuclease H-like
  • 47819 - HRDC-like
  • 47819 - HRDC-like
  • 0Direct
    56672,46919,53098
  • 56672 - DNA/RNA polymerases
  • 46919 - N-terminal Zn binding domain of HIV integrase
  • 53098 - Ribonuclease H-like
  • 0Direct
    49562,54236,54236
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 54236 - Ubiquitin-like
  • 54236 - Ubiquitin-like
  • 0Direct
    49265,49265,49265
  • 49265 - Fibronectin type III
  • 49265 - Fibronectin type III
  • 49265 - Fibronectin type III
  • 0Direct
    56672,53098,51283
  • 56672 - DNA/RNA polymerases
  • 53098 - Ribonuclease H-like
  • 51283 - dUTPase-like
  • 0Direct
    82708,53098,54928
  • 82708 - R3H domain
  • 53098 - Ribonuclease H-like
  • 54928 - RNA-binding domain, RBD
  • 0Direct
    64268,50729,56024
  • 64268 - PX domain
  • 50729 - PH domain-like
  • 56024 - Phospholipase D/nuclease
  • 0Direct
    55550,55550,52799
  • 55550 - SH2 domain
  • 55550 - SH2 domain
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 0Direct
    46938,52087,52799
  • 46938 - CRAL/TRIO N-terminal domain
  • 52087 - CRAL/TRIO domain
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 0Direct
    47943,47353,57756
  • 47943 - Retrovirus capsid protein, N-terminal core domain
  • 47353 - Retrovirus capsid dimerization domain-like
  • 57756 - Retrovirus zinc finger-like domains
  • 0Direct
    55550,55550,50044
  • 55550 - SH2 domain
  • 55550 - SH2 domain
  • 50044 - SH3-domain
  • 0Direct
    81324,52799,49562
  • 81324 - Voltage-gated potassium channels
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 0Direct
    50630,56672,46919
  • 50630 - Acid proteases
  • 56672 - DNA/RNA polymerases
  • 46919 - N-terminal Zn binding domain of HIV integrase
  • 0Direct
    57756,50630,56672
  • 57756 - Retrovirus zinc finger-like domains
  • 50630 - Acid proteases
  • 56672 - DNA/RNA polymerases
  • 0Direct
    56784,54211,54211
  • 56784 - HAD-like
  • 54211 - Ribosomal protein S5 domain 2-like
  • 54211 - Ribosomal protein S5 domain 2-like
  • 0Direct
    90188,90188,53649
  • 90188 - Somatomedin B domain
  • 90188 - Somatomedin B domain
  • 53649 - Alkaline phosphatase-like
  • 0Direct
    54637,54637,55961
  • 54637 - Thioesterase/thiol ester dehydrase-isomerase
  • 54637 - Thioesterase/thiol ester dehydrase-isomerase
  • 55961 - Bet v1-like
  • 0Direct
    51283,50630,56672
  • 51283 - dUTPase-like
  • 50630 - Acid proteases
  • 56672 - DNA/RNA polymerases
  • 0Direct
    56672,53098,46919
  • 56672 - DNA/RNA polymerases
  • 53098 - Ribonuclease H-like
  • 46919 - N-terminal Zn binding domain of HIV integrase
  • 0Direct
    56568,47233,52799
  • 56568 - Non-globular alpha+beta subunits of globular proteins
  • 47233 - Bacterial GAP domain
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 0Direct
    48726,49265,49265
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 49265 - Fibronectin type III
  • 0.00000000000002043Direct
    54236,47031,50729
  • 54236 - Ubiquitin-like
  • 47031 - Second domain of FERM
  • 50729 - PH domain-like
  • 0.000000000496Direct
    48726,48726,49265
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 0.00000001181Direct
    51735,47336,53474
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 47336 - ACP-like
  • 53474 - alpha/beta-Hydrolases
  • 0.00000006418Direct
    109604,81301,81271
  • 109604 - HD-domain/PDEase-like
  • 81301 - Nucleotidyltransferase
  • 81271 - TGS-like
  • 0.000005508Direct
    50129,51735,51735
  • 50129 - GroES-like
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 0.0004004Direct
    48726,48726,48726
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 0.004913Inherited
    51735,51735,47336
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 47336 - ACP-like
  • 0.01493Inherited
    57756,51283,50630
  • 57756 - Retrovirus zinc finger-like domains
  • 51283 - dUTPase-like
  • 50630 - Acid proteases
  • 0.01783Inherited
    47353,57756,57756
  • 47353 - Retrovirus capsid dimerization domain-like
  • 57756 - Retrovirus zinc finger-like domains
  • 57756 - Retrovirus zinc finger-like domains
  • 0.02936Inherited
    57756,57756,51283
  • 57756 - Retrovirus zinc finger-like domains
  • 57756 - Retrovirus zinc finger-like domains
  • 51283 - dUTPase-like
  • 0.02936Inherited


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