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Enzyme Commission (EC): Acting on ester bonds

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Root: EC Hierarchy (from IntEnz release 70)

Shortest distance to current term (+ for parents, - for children) EC term [EC ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + 2:   root [root] <7>
+ 1:   Hydrolases [3] <13>(395|668) (394|417|206)
0:   Acting on ester bonds [3.1] <23>(157|226) (157|126|55)
- 1:   Phosphoric monoester hydrolases [3.1.3] <111>(60|78) (60|45|12)
- 1:   Carboxylic ester hydrolases [3.1.1] <108>(35|49) (35|13|0)
- 1:   Phosphoric diester hydrolases [3.1.4] <61>(31|30) (31|22|13)
- 1:   Site specific endodeoxyribonucleases: cleavage is sequence specific [3.1.23] <59>(0|0) (0|0|0)
- 1:   Thiolester hydrolases [3.1.2] <34>(16|19) (16|11|4)
- 1:   Sulfuric ester hydrolases [3.1.6] <20>(1|1) (1|0|0)
- 1:   Endoribonucleases producing 5'-phosphomonoesters [3.1.26] <15>(23|29) (23|21|20)
- 1:   Diphosphoric monoester hydrolases [3.1.7] <12>(6|4) (6|3|1)
- 1:   Endoribonucleases producing other than 5'-phosphomonoesters [3.1.27] <10>(1|2) (1|0|0)
- 1:   Endodeoxyribonucleases producing 5'-phosphomonoesters [3.1.21] <9>(6|4) (6|1|0)
- 1:   Exodeoxyribonucleases producing 5'-phosphomonoesters [3.1.11] <8>(11|8) (11|3|0)
- 1:   Endodeoxyribonucleases producing other than 5'-phosphomonoesters [3.1.22] <5>(3|4) (3|0|0)
- 1:   Exoribonucleases producing 5'-phosphomonoesters [3.1.13] <5>(19|19) (19|18|13)
- 1:   Site specific endodeoxyribonucleases: cleavage is not sequence specific [3.1.24] <4>(0|0) (0|0|0)
- 1:   Endoribonucleases active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoest [3.1.30] <2>(1|1) (1|0|0)
- 1:   Exodeoxyribonucleases producing 3'-phosphomonoesters [3.1.12] <2>(2|1) (2|1|0)
- 1:   Phosphoric triester hydrolases [3.1.8] <2>(1|1) (1|0|0)
- 1:   Site-specific endodeoxyribonucleases specific for altered bases [3.1.25] <2>(0|0) (0|0|0)
- 1:   Endoribonucleases active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoest [3.1.31] <1>(2|2) (2|3|3)
- 1:   Exonucleases active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters [3.1.16] <1>(0|0) (0|0|0)
- 1:   Exonucleases active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters [3.1.15] <1>(0|0) (0|0|0)
- 1:   Exoribonucleases producing 3'-phosphomonoesters [3.1.14] <1>(0|0) (0|0|0)
- 1:   Triphosphoric monoester hydrolases [3.1.5] <1>(1|1) (1|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
Retrovirus zinc finger-like domains0Direct
DTD-like0Direct
HD-domain/PDEase-like0Direct
ComB-like0Direct
SGNH hydrolase0Direct
PAZ domain0Direct
PLC-like phosphodiesterases0Direct
L9 N-domain-like0Direct
Lipase/lipooxygenase domain (PLAT/LH2 domain)0Direct
DNA/RNA polymerases0Direct
Plant invertase/pectin methylesterase inhibitor0Direct
PHP domain-like0Direct
CheY-like0Direct
Methylesterase CheB, C-terminal domain0Direct
Microbial ribonucleases0Direct
Toprim domain0Direct
Phospholipase D/nuclease0Direct
Metallo-dependent phosphatases0Direct
DNase I-like0Direct
Outer membrane phospholipase A (OMPLA)0Direct
Nitrous oxide reductase, N-terminal domain0Direct
HAD-like0Direct
Ribonuclease H-like0Direct
FabD/lysophospholipase-like0Direct
Somatomedin B domain0Direct
Xylose isomerase-like0Direct
Putative isomerase YbhE0Direct
C2 domain (Calcium/lipid-binding domain, CaLB)0Direct
Acid phosphatase/Vanadium-dependent haloperoxidase0Direct
GAF domain-like0Direct
Carbohydrate phosphatase0Direct
Purple acid phosphatase, N-terminal domain0Direct
Phospholipase A2, PLA20Direct
Peptidyl-tRNA hydrolase II0Direct
AlbA-like0Direct
XseB-like0Direct
cAMP-binding domain-like0Direct
Rhodanese/Cell cycle control phosphatase0Direct
dsRNA-binding domain-like0Direct
Thermostable phytase (3-phytase)0Direct
Phosphoglycerate mutase-like0Direct
EAL domain-like0Direct
Peptidyl-tRNA hydrolase-like0Direct
Retrovirus capsid protein, N-terminal core domain0Direct
Phospholipase C/P1 nuclease0Direct
Bacterial GAP domain0Direct
CRAL/TRIO N-terminal domain0Direct
Phosphotyrosine protein phosphatases I0Direct
Voltage-gated potassium channels0Direct
Peptidyl-tRNA hydrolase domain-like0Direct
Retrovirus capsid dimerization domain-like0Direct
Calcium-dependent phosphotriesterase0Direct
Staphylococcal nuclease0Direct
Viral protein domain0Direct
N-terminal Zn binding domain of HIV integrase0Direct
RNase III domain-like0Direct
His-Me finger endonucleases0Direct
PP2C-like0Direct
Rnp2-like0Direct
C-terminal domain of PLC-beta0Direct
Metallo-hydrolase/oxidoreductase0Direct
DNA-binding domain of retroviral integrase0Direct
Retroviral matrix proteins0Direct
Rof/RNase P subunit-like0Direct
Sulfolobus fructose-1,6-bisphosphatase-like0Direct
Protein serine/threonine phosphatase 2C, C-terminal domain0Direct
Influenza hemagglutinin (stalk)0Direct
AF0625-like0Direct
Ribosomal protein S5 domain 2-like0Direct
(Phosphotyrosine protein) phosphatases II0Direct
Holliday junction resolvase RusA0Direct
PH domain-like0Direct
SurE-like0Direct
alpha/beta-Hydrolases0Direct
WD40 repeat-like0.000000000000001515Direct
Alkaline phosphatase-like0.000000000000003512Direct
LigT-like0.00000000000001191Direct
Fibronectin type III0.00000000000004106Direct
EF-hand0.0000000000001382Direct
5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain0.00000000006961Direct
DEK C-terminal domain0.000000002363Direct
DNA clamp0.000000004648Direct
SMAD/FHA domain0.00000002659Direct
PX domain0.0000001094Direct
Second domain of FERM0.0000001703Direct
L domain-like0.0000005247Direct
Thioesterase/thiol ester dehydrase-isomerase0.0000005358Direct
SH2 domain0.000002604Direct
Restriction endonuclease-like0.000003726Direct
GTPase activation domain, GAP0.000005028Direct
Integrin alpha N-terminal domain0.000005028Direct
Ras GEF0.000006737Direct
Saposin0.000008573Direct
Acid proteases0.00003895Direct
Immunoglobulin0.00005039Direct
C-terminal (heme d1) domain of cytochrome cd1-nitrite reductase0.00005426Direct
ssDNA viruses0.00009274Direct
Chaperone J-domain0.0002512Direct
CYTH-like phosphatases0.0009218Direct
NTF2-like0.001829Inherited
CRAL/TRIO domain0.00274Inherited
HRDC-like0.006164Inherited
Pectin lyase-like0.01048Inherited
RNA-binding domain, RBD0.01742Inherited
Kelch motif0.02127Inherited
Non-globular alpha+beta subunits of globular proteins0.02579Inherited
Ubiquitin-like0.063Inherited
L30e-like0.07718Inherited
PIN domain-like0.08483Inherited
R3H domain0.1142Inherited
Probable ACP-binding domain of malonyl-CoA ACP transacylase0.2201Inherited
Methylated DNA-protein cysteine methyltransferase, C-terminal domain0.2269Inherited
Bet v1-like0.2413Inherited
Quinoprotein alcohol dehydrogenase-like0.2513Inherited
PYP-like sensor domain (PAS domain)0.2986Inherited
Hedgehog/intein (Hint) domain0.3193Inherited
Autotransporter0.3199Inherited
ACP-like0.3301Inherited
Carbonic anhydrase0.375Inherited
Ankyrin repeat0.4098Inherited
SAM/Pointed domain0.4301Inherited
SH3-domain0.4755Inherited
FYVE/PHD zinc finger0.6316Inherited
TPR-like0.7065Inherited
Starch-binding domain-like0.7502Inherited
HIT-like0.9589Inherited
Tudor/PWWP/MBT0.961Inherited
PDZ domain-like1Inherited
Thiolase-like1Inherited
Nucleotidyltransferase1Inherited
NagB/RpiA/CoA transferase-like1Inherited
ClpP/crotonase1Inherited
TGS-like1Inherited
beta-lactamase/transpeptidase-like1Inherited
UDP-Glycosyltransferase/glycogen phosphorylase1Inherited
P-loop containing nucleoside triphosphate hydrolases1Inherited
Phosphoenolpyruvate/pyruvate domain1Inherited
Nucleic acid-binding proteins1Inherited
GroES-like1Inherited
Nucleotide cyclase1Inherited
S-adenosyl-L-methionine-dependent methyltransferases1Inherited
Concanavalin A-like lectins/glucanases1Inherited
Inosine monophosphate dehydrogenase (IMPDH)1Inherited
DNA ligase/mRNA capping enzyme, catalytic domain1Inherited
dUTPase-like1Inherited
Thioredoxin-like1Inherited
NAD(P)-binding Rossmann-fold domains1Inherited
AraD/HMP-PK domain-like1Inherited
Terpenoid synthases1Inherited
DHH phosphoesterases1Inherited
Periplasmic binding protein-like II1Inherited
Glycoside hydrolase/deacetylase1Inherited
Macro domain-like1Inherited
Terpenoid cyclases/Protein prenyltransferases1Inherited
Glutaminase/Asparaginase1Inherited
ACT-like1Inherited
Cysteine proteinases1Inherited


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Family

(show details)
SCOP termFDR (all)Annotation (direct or inherited)
Class B acid phosphatase, AphA0Direct
XseB-like0Direct
Inositol monophosphatase/fructose-1,6-bisphosphatase-like0Direct
2'-5' RNA ligase LigT0Direct
AF0625-like0Direct
Retrovirus capsid protein, N-terminal core domain0Direct
Thermostable phytase (3-phytase)0Direct
Staphylococcal nuclease0Direct
Enolase-phosphatase E10Direct
Fungal ribonucleases0Direct
4HBT-like0Direct
SGL-like0Direct
Nitrous oxide reductase, N-terminal domain0Direct
RecU-like0Direct
Exodeoxyribonuclease V beta chain (RecC), C-terminal domain0Direct
Outer membrane phospholipase A (OMPLA)0Direct
Higher-molecular-weight phosphotyrosine protein phosphatases0Direct
Double-stranded RNA-binding domain (dsRBD)0Direct
Colipase-binding domain0Direct
CheY-related0Direct
Acyl-ACP thioesterase-like0Direct
Endonuclease IV0Direct
P1 nuclease0Direct
YihX-like0Direct
Integrin alpha N-terminal domain0Direct
Inositol polyphosphate 5-phosphatase (IPP5)0Direct
EF-hand modules in multidomain proteins0Direct
DnaQ-like 3'-5' exonuclease0Direct
Arylsulfatase0Direct
NLI interacting factor-like phosphatase0Direct
Sulfolobus fructose-1,6-bisphosphatase-like0Direct
RuvC resolvase0Direct
GpdQ-like0Direct
Sphingomyelin phosphodiesterase-like0Direct
Hemagglutinin domain of haemagglutinin-esterase-fusion glycoprotein HEF10Direct
Glycerophosphoryl diester phosphodiesterase0Direct
Lysophospholipase0Direct
SurE-like0Direct
Peptidyl-tRNA hydrolase II0Direct
Vertebrate phospholipase A20Direct
Bacterial ribonucleases0Direct
Pancreatic lipase, N-terminal domain0Direct
Toprim domain0Direct
Dienelactone hydrolase0Direct
Methylesterase CheB, C-terminal domain0Direct
Reverse transcriptase0Direct
Plant invertase/pectin methylesterase inhibitor0Direct
RNase P subunit p300Direct
Hypothetical esterase YJL068C0Direct
Putative acetylxylan esterase-like0Direct
Cutinase-like0Direct
Alkaline phosphatase0Direct
MMLV matrix protein-like0Direct
Endonuclease I0Direct
beta-Phosphoglucomutase-like0Direct
PAZ domain0Direct
N-terminal domain of RNase HI0Direct
Ribonuclease H0Direct
Esterase0Direct
Mammalian PLC0Direct
Putative isomerase YbhE0Direct
Gastric lipase0Direct
Histidine acid phosphatase0Direct
GlpX-like bacterial fructose-1,6-bisphosphatase0Direct
Phosphoserine phosphatase0Direct
HTLV-II matrix protein0Direct
Influenza hemagglutinin (stalk)0Direct
Phospholipase C0Direct
Thioesterases0Direct
EAL domain0Direct
ComB-like0Direct
GAG polyprotein M-domain0Direct
DTD-like0Direct
Myotubularin-like phosphatases0Direct
Magnesium-dependent phosphatase-1, Mdp10Direct
Glyoxalase II (hydroxyacylglutathione hydrolase)0Direct
Purple acid phosphatase, N-terminal domain0Direct
PP2C-like0Direct
Cell cycle control phosphatase, catalytic domain0Direct
Retrovirus capsid protein C-terminal domain0Direct
RNase P protein0Direct
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, phosphatase domain0Direct
L30e/L7ae ribosomal proteins0Direct
5' nucleotidase-like0Direct
RNase P subunit p29-like0Direct
Acyl-CoA thioesterase0Direct
Pyrimidine 5'-nucleotidase (UMPH-1)0Direct
Carboxylesterase0Direct
Peptidyl-tRNA hydrolase domain0Direct
Pectin methylesterase0Direct
GAF domain0Direct
Bacterial GAP domain0Direct
Histidinol phosphatase-like0Direct
Protein serine/threonine phosphatase 2C, C-terminal domain0Direct
Patatin0Direct
Somatomedin B domain0Direct
RNB domain-like0Direct
RNase Z-like0Direct
Retroviral protease (retropepsin)0Direct
2',3'-cyclic nucleotide 3'-phosphodiesterase, catalytic domain0Direct
CRAL/TRIO N-terminal domain0Direct
Rpp14/Pop5-like0Direct
Holliday junction resolvase RusA0Direct
C-terminal domain of PLC-beta0Direct
TAP-like0Direct
CRAL/TRIO domain0Direct
Protein serine/threonine phosphatase0Direct
Low-molecular-weight phosphotyrosine protein phosphatases0Direct
RNase D C-terminal domains0Direct
Dual specificity phosphatase-like0Direct
Fungal lipases0Direct
Predicted hydrolases Cof0Direct
CAF1-like ribonuclease0Direct
Virulence effector SptP domain0Direct
Parvoviridae-like VP0Direct
Biotin biosynthesis protein BioH0Direct
Esterase domain of haemagglutinin-esterase-fusion glycoprotein HEF10Direct
Phosphotriesterase-like0Direct
Purple acid phosphatase-like0Direct
Type 2 phosphatidic acid phosphatase, PAP20Direct
Retroviral integrase, catalytic domain0Direct
Trehalose-phosphatase0Direct
RNase III catalytic domain-like0Direct
N-terminal Zn binding domain of HIV integrase0Direct
mRNA triphosphatase CET10Direct
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, kinase domain0Direct
tRNA splicing product Appr>p cyclic nucleotide phosphodiesterase0Direct
Hjc-like0Direct
PLC-like (P variant)0Direct
Nuclease0Direct
Bacterial lipase0Direct
GRAM domain0Direct
Alpha-toxin, C-terminal domain0Direct
Immunodeficiency virus matrix proteins0Direct
Acetylcholinesterase-like0Direct
Retrovirus zinc finger-like domains0Direct
cAMP-binding domain0Direct
Serum paraoxonase/arylesterase 1, PON10Direct
HD domain0Direct
Peptidyl-tRNA hydrolase-like0Direct
DNA-binding domain of retroviral integrase0Direct
MtnX-like0Direct
DNA/RNA non-specific endonuclease0Direct
PDEase0Direct
Insect phospholipase A20Direct
Fibronectin type III0.00000000000001192Direct
Acetylhydrolase0.00000000001248Direct
Pleckstrin-homology domain (PH domain)0.00000000001541Direct
Cold shock DNA-binding domain-like0.00000000002194Direct
5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain0.00000000003287Direct
5'-nucleotidase (syn. UDP-sugar hydrolase), N-terminal domain0.00000000003287Direct
DNase I-like0.0000000001843Direct
Third domain of FERM0.0000000003774Direct
phosphatase domain of polynucleotide kinase0.000000003432Direct
First domain of FERM0.00000002759Direct
FHA domain0.00000005372Direct
Second domain of FERM0.00000008589Direct
Acyl-carrier protein (ACP)0.0000003693Direct
DEK C-terminal domain0.0000003693Direct
I set domains0.0000004792Direct
Probable phosphatase YrbI0.0000008356Direct
PaaI/YdiI-like0.000000937Direct
Imidazole glycerol phosphate dehydratase0.000001092Direct
SH2 domain0.000001656Direct
PHP domain0.000003133Direct
BCR-homology GTPase activation domain (BH-domain)0.000003877Direct
PX domain0.000004156Direct
NagD-like0.000005211Direct
Ras GEF0.000005226Direct
RelA/SpoT domain0.000007758Direct
Thioesterase domain of polypeptide, polyketide and fatty acid synthases0.0000131Direct
Canonical RBD0.00001772Direct
CoA transferase alpha subunit-like0.00002824Direct
Leucine rich effector protein YopM0.0000354Direct
PDZ domain0.00003945Direct
Macro domain0.00004143Direct
Hydroxynitrile lyase-like0.00007175Direct
FYVE, a phosphatidylinositol-3-phosphate binding domain0.0001059Direct
Chaperone J-domain0.0002025Direct
MaoC-like0.000232Direct
FabD-like0.0003983Direct
PP1699/LP2961-like0.0007379Direct
Haloperoxidase0.0008409Direct
mRNA capping enzyme0.001085Inherited
Mason-Pfizer monkey virus matrix protein0.01441Inherited
MAM domain0.01574Inherited
HpcH/HpaI aldolase0.0266Inherited
mRNA cap (Guanine N-7) methyltransferase0.02928Inherited
WD40-repeat0.03644Inherited
Ras-binding domain, RBD0.05406Inherited
GGDEF domain0.0664Inherited
5' to 3' exonuclease catalytic domain0.07304Inherited
Ubiquitin-related0.08702Inherited
R3H domain0.09203Inherited
Tetratricopeptide repeat (TPR)0.1825Inherited
SAM (sterile alpha motif) domain0.1956Inherited
Methylated DNA-protein cysteine methyltransferase, C-terminal domain0.2014Inherited
Probable ACP-binding domain of malonyl-CoA ACP transacylase0.2353Inherited
Tudor domain0.2787Inherited
Carbonic anhydrase0.3297Inherited
Ankyrin repeat0.3486Inherited
Trehalose-6-phosphate synthase, OtsA0.3592Inherited
DNA polymerase I0.3604Inherited
Starch-binding domain0.3827Inherited
SH3-domain0.4328Inherited
Glucose 6-phosphate dehydrogenase-like0.836Inherited
Crotonase-like0.8378Inherited
Epoxide hydrolase0.9161Inherited
AraD-like aldolase/epimerase0.9271Inherited
Cofactor-dependent phosphoglycerate mutase0.9857Inherited
Carbon-carbon bond hydrolase0.9935Inherited
Tandem AAA-ATPase domain1Inherited
dUTPase-like1Inherited
Thiolase-related1Inherited
Tyrosine-dependent oxidoreductases1Inherited
Terpenoid cyclase N-terminal domain1Inherited
Glutathione peroxidase-like1Inherited
Alcohol dehydrogenase-like, N-terminal domain1Inherited
Nucleotide and nucleoside kinases1Inherited
beta-Lactamase/D-ala carboxypeptidase1Inherited
Alcohol dehydrogenase-like, C-terminal domain1Inherited
NagB-like1Inherited
Glutaminase/Asparaginase1Inherited
Phosphate binding protein-like1Inherited
Exodeoxyribonuclease V beta chain (RecB), C-terminal domain1Inherited
Terpenoid cyclase C-terminal domain1Inherited


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Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Calcium-dependent phosphotriesterase0Direct
Rhodanese/Cell cycle control phosphatase0Direct
Nitrous oxide reductase, N-terminal domain0Direct
CRAL/TRIO N-terminal domain0Direct
PP2C-like0Direct
HAD-like0Direct
Toprim domain0Direct
Metallo-dependent phosphatases0Direct
ComB-like0Direct
SurE-like0Direct
Plant invertase/pectin methylesterase inhibitor0Direct
RNase III domain-like0Direct
Microbial ribonucleases0Direct
PAZ domain0Direct
CheY-like0Direct
Phospholipase A2, PLA20Direct
PHP domain-like0Direct
His-Me finger endonucleases0Direct
Peptidyl-tRNA hydrolase-like0Direct
AlbA-like0Direct
Retrovirus capsid protein, N-terminal core domain0Direct
dsRNA-binding domain-like0Direct
C-terminal domain of PLC-beta0Direct
Phospholipase D/nuclease0Direct
PH domain-like0Direct
Influenza hemagglutinin (stalk)0Direct
GAF domain-like0Direct
Peptidyl-tRNA hydrolase domain-like0Direct
alpha/beta-Hydrolases0Direct
Staphylococcal nuclease0Direct
Phosphotyrosine protein phosphatases I0Direct
DNA-binding domain of retroviral integrase0Direct
Retroviral matrix proteins0Direct
Holliday junction resolvase RusA0Direct
Protein serine/threonine phosphatase 2C, C-terminal domain0Direct
L9 N-domain-like0Direct
DNase I-like0Direct
SGNH hydrolase0Direct
Peptidyl-tRNA hydrolase II0Direct
Sulfolobus fructose-1,6-bisphosphatase-like0Direct
Acid phosphatase/Vanadium-dependent haloperoxidase0Direct
cAMP-binding domain-like0Direct
N-terminal Zn binding domain of HIV integrase0Direct
PLC-like phosphodiesterases0Direct
Phosphoglycerate mutase-like0Direct
Ribonuclease H-like0Direct
Purple acid phosphatase, N-terminal domain0Direct
FabD/lysophospholipase-like0Direct
Xylose isomerase-like0Direct
AF0625-like0Direct
HD-domain/PDEase-like0Direct
Viral protein domain0Direct
DTD-like0Direct
C2 domain (Calcium/lipid-binding domain, CaLB)0Direct
Methylesterase CheB, C-terminal domain0Direct
Lipase/lipooxygenase domain (PLAT/LH2 domain)0Direct
Phospholipase C/P1 nuclease0Direct
DNA/RNA polymerases0Direct
Carbohydrate phosphatase0Direct
Putative isomerase YbhE0Direct
Outer membrane phospholipase A (OMPLA)0Direct
(Phosphotyrosine protein) phosphatases II0Direct
Retrovirus capsid dimerization domain-like0Direct
Bacterial GAP domain0Direct
Ribosomal protein S5 domain 2-like0Direct
Thermostable phytase (3-phytase)0Direct
Somatomedin B domain0Direct
Retrovirus zinc finger-like domains0Direct
Rnp2-like0Direct
Metallo-hydrolase/oxidoreductase0Direct
EAL domain-like0Direct
XseB-like0Direct
Voltage-gated potassium channels0Direct
Rof/RNase P subunit-like0Direct
WD40 repeat-like0.000000000000001058Direct
Alkaline phosphatase-like0.000000000000002458Direct
LigT-like0.000000000000008372Direct
Fibronectin type III0.00000000000002903Direct
EF-hand0.00000000000009814Direct
5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain0.00000000005099Direct
DEK C-terminal domain0.000000001769Direct
DNA clamp0.000000003494Direct
SMAD/FHA domain0.0000000202Direct
PX domain0.00000008371Direct
Second domain of FERM0.0000001308Direct
L domain-like0.000000407Direct
Thioesterase/thiol ester dehydrase-isomerase0.0000004156Direct
SH2 domain0.000002042Direct
Restriction endonuclease-like0.000002932Direct
GTPase activation domain, GAP0.000003957Direct
Integrin alpha N-terminal domain0.000003957Direct
Ras GEF0.00000531Direct
Saposin0.000006774Direct
Acid proteases0.00003116Direct
Immunoglobulin0.00004041Direct
C-terminal (heme d1) domain of cytochrome cd1-nitrite reductase0.00004353Direct
ssDNA viruses0.00007482Direct
Chaperone J-domain0.0002044Direct
CYTH-like phosphatases0.0007599Direct
NTF2-like0.00152Inherited
CRAL/TRIO domain0.002288Inherited
HRDC-like0.005191Inherited
Pectin lyase-like0.008886Inherited
RNA-binding domain, RBD0.01486Inherited
Kelch motif0.01818Inherited
Non-globular alpha+beta subunits of globular proteins0.0221Inherited
Ubiquitin-like0.05464Inherited
L30e-like0.06708Inherited
PIN domain-like0.07383Inherited
R3H domain0.09989Inherited
Probable ACP-binding domain of malonyl-CoA ACP transacylase0.1957Inherited
Methylated DNA-protein cysteine methyltransferase, C-terminal domain0.202Inherited
Bet v1-like0.2152Inherited
Quinoprotein alcohol dehydrogenase-like0.2244Inherited
PYP-like sensor domain (PAS domain)0.2694Inherited
Hedgehog/intein (Hint) domain0.2885Inherited
Autotransporter0.2891Inherited
ACP-like0.2983Inherited
Carbonic anhydrase0.3396Inherited
Ankyrin repeat0.3717Inherited
SAM/Pointed domain0.3911Inherited
SH3-domain0.4337Inherited
FYVE/PHD zinc finger0.58Inherited
TPR-like0.6497Inherited
Starch-binding domain-like0.6903Inherited
HIT-like0.8872Inherited
Tudor/PWWP/MBT0.8891Inherited
AraD/HMP-PK domain-like0.9302Inherited
Nucleotide cyclase1Inherited
Glycoside hydrolase/deacetylase1Inherited
NagB/RpiA/CoA transferase-like1Inherited
TGS-like1Inherited
DNA ligase/mRNA capping enzyme, catalytic domain1Inherited
NAD(P)-binding Rossmann-fold domains1Inherited
Nucleic acid-binding proteins1Inherited
UDP-Glycosyltransferase/glycogen phosphorylase1Inherited
Terpenoid cyclases/Protein prenyltransferases1Inherited
ClpP/crotonase1Inherited
dUTPase-like1Inherited
Inosine monophosphate dehydrogenase (IMPDH)1Inherited
PDZ domain-like1Inherited
Macro domain-like1Inherited
Phosphoenolpyruvate/pyruvate domain1Inherited
DHH phosphoesterases1Inherited
Glutaminase/Asparaginase1Inherited
P-loop containing nucleoside triphosphate hydrolases1Inherited
Nucleotidyltransferase1Inherited
Thiolase-like1Inherited
Cysteine proteinases1Inherited
Periplasmic binding protein-like II1Inherited
ACT-like1Inherited
Thioredoxin-like1Inherited
Terpenoid synthases1Inherited
beta-lactamase/transpeptidase-like1Inherited
S-adenosyl-L-methionine-dependent methyltransferases1Inherited
Concanavalin A-like lectins/glucanases1Inherited
GroES-like1Inherited

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
101148,51126
  • 101148 - Plant invertase/pectin methylesterase inhibitor
  • 51126 - Pectin lyase-like
  • 0Direct
    52151,52151
  • 52151 - FabD/lysophospholipase-like
  • 52151 - FabD/lysophospholipase-like
  • 0Direct
    52540,53254
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 53254 - Phosphoglycerate mutase-like
  • 0Direct
    53098,46919
  • 53098 - Ribonuclease H-like
  • 46919 - N-terminal Zn binding domain of HIV integrase
  • 0Direct
    90188,90188
  • 90188 - Somatomedin B domain
  • 90188 - Somatomedin B domain
  • 0Direct
    56784,54211
  • 56784 - HAD-like
  • 54211 - Ribosomal protein S5 domain 2-like
  • 0Direct
    50729,47473
  • 50729 - PH domain-like
  • 47473 - EF-hand
  • 0Direct
    53098,53098
  • 53098 - Ribonuclease H-like
  • 53098 - Ribonuclease H-like
  • 0Direct
    50249,56300
  • 50249 - Nucleic acid-binding proteins
  • 56300 - Metallo-dependent phosphatases
  • 0Direct
    50199,63748
  • 50199 - Staphylococcal nuclease
  • 63748 - Tudor/PWWP/MBT
  • 0Direct
    69065,69065
  • 69065 - RNase III domain-like
  • 69065 - RNase III domain-like
  • 0Direct
    52821,52799
  • 52821 - Rhodanese/Cell cycle control phosphatase
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 0Direct
    55781,55781
  • 55781 - GAF domain-like
  • 55781 - GAF domain-like
  • 0Direct
    56568,47233
  • 56568 - Non-globular alpha+beta subunits of globular proteins
  • 47233 - Bacterial GAP domain
  • 0Direct
    101690,53098
  • 101690 - PAZ domain
  • 53098 - Ribonuclease H-like
  • 0Direct
    52799,52799
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 0Direct
    55154,56091
  • 55154 - CYTH-like phosphatases
  • 56091 - DNA ligase/mRNA capping enzyme, catalytic domain
  • 0Direct
    53639,56784
  • 53639 - AraD/HMP-PK domain-like
  • 56784 - HAD-like
  • 0Direct
    81606,81601
  • 81606 - PP2C-like
  • 81601 - Protein serine/threonine phosphatase 2C, C-terminal domain
  • 0Direct
    53098,50122
  • 53098 - Ribonuclease H-like
  • 50122 - DNA-binding domain of retroviral integrase
  • 0Direct
    81324,52799
  • 81324 - Voltage-gated potassium channels
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 0Direct
    46938,52087
  • 46938 - CRAL/TRIO N-terminal domain
  • 52087 - CRAL/TRIO domain
  • 0Direct
    52087,52799
  • 52087 - CRAL/TRIO domain
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 0Direct
    47233,52799
  • 47233 - Bacterial GAP domain
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 0Direct
    55550,52799
  • 55550 - SH2 domain
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 0Direct
    49363,56300
  • 49363 - Purple acid phosphatase, N-terminal domain
  • 56300 - Metallo-dependent phosphatases
  • 0Direct
    53649,54060
  • 53649 - Alkaline phosphatase-like
  • 54060 - His-Me finger endonucleases
  • 0Direct
    53474,49723
  • 53474 - alpha/beta-Hydrolases
  • 49723 - Lipase/lipooxygenase domain (PLAT/LH2 domain)
  • 0Direct
    49899,48726
  • 49899 - Concanavalin A-like lectins/glucanases
  • 48726 - Immunoglobulin
  • 0Direct
    56219,54928
  • 56219 - DNase I-like
  • 54928 - RNA-binding domain, RBD
  • 0Direct
    49452,52799
  • 49452 - Starch-binding domain-like
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 0Direct
    52266,49818
  • 52266 - SGNH hydrolase
  • 49818 - Viral protein domain
  • 0Direct
    55550,55550
  • 55550 - SH2 domain
  • 55550 - SH2 domain
  • 0Direct
    49562,54236
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 54236 - Ubiquitin-like
  • 0Direct
    56784,53474
  • 56784 - HAD-like
  • 53474 - alpha/beta-Hydrolases
  • 0Direct
    69065,54768
  • 69065 - RNase III domain-like
  • 54768 - dsRNA-binding domain-like
  • 0Direct
    52266,103515
  • 52266 - SGNH hydrolase
  • 103515 - Autotransporter
  • 0Direct
    54637,55961
  • 54637 - Thioesterase/thiol ester dehydrase-isomerase
  • 55961 - Bet v1-like
  • 0Direct
    90188,53649
  • 90188 - Somatomedin B domain
  • 53649 - Alkaline phosphatase-like
  • 0Direct
    47943,47353
  • 47943 - Retrovirus capsid protein, N-terminal core domain
  • 47353 - Retrovirus capsid dimerization domain-like
  • 0Direct
    48452,56300
  • 48452 - TPR-like
  • 56300 - Metallo-dependent phosphatases
  • 0Direct
    52058,56219
  • 52058 - L domain-like
  • 56219 - DNase I-like
  • 0Direct
    56784,54427
  • 56784 - HAD-like
  • 54427 - NTF2-like
  • 0Direct
    47473,51695
  • 47473 - EF-hand
  • 51695 - PLC-like phosphodiesterases
  • 0Direct
    101908,56219
  • 101908 - Putative isomerase YbhE
  • 56219 - DNase I-like
  • 0Direct
    48537,49723
  • 48537 - Phospholipase C/P1 nuclease
  • 49723 - Lipase/lipooxygenase domain (PLAT/LH2 domain)
  • 0Direct
    51695,49562
  • 51695 - PLC-like phosphodiesterases
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 0Direct
    57756,50630
  • 57756 - Retrovirus zinc finger-like domains
  • 50630 - Acid proteases
  • 0Direct
    53098,54928
  • 53098 - Ribonuclease H-like
  • 54928 - RNA-binding domain, RBD
  • 0Direct
    51695,51695
  • 51695 - PLC-like phosphodiesterases
  • 51695 - PLC-like phosphodiesterases
  • 0Direct
    47836,47943
  • 47836 - Retroviral matrix proteins
  • 47943 - Retrovirus capsid protein, N-terminal core domain
  • 0Direct
    51069,49265
  • 51069 - Carbonic anhydrase
  • 49265 - Fibronectin type III
  • 0Direct
    55550,50044
  • 55550 - SH2 domain
  • 50044 - SH3-domain
  • 0Direct
    55658,53098
  • 55658 - L9 N-domain-like
  • 53098 - Ribonuclease H-like
  • 0Direct
    109715,52799
  • 109715 - DEK C-terminal domain
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 0Direct
    50199,50199
  • 50199 - Staphylococcal nuclease
  • 50199 - Staphylococcal nuclease
  • 0Direct
    52540,55144
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 55144 - LigT-like
  • 0Direct
    48403,52151
  • 48403 - Ankyrin repeat
  • 52151 - FabD/lysophospholipase-like
  • 0Direct
    56672,53098
  • 56672 - DNA/RNA polymerases
  • 53098 - Ribonuclease H-like
  • 0Direct
    51283,46919
  • 51283 - dUTPase-like
  • 46919 - N-terminal Zn binding domain of HIV integrase
  • 0Direct
    56219,56219
  • 56219 - DNase I-like
  • 56219 - DNase I-like
  • 0Direct
    47353,57756
  • 47353 - Retrovirus capsid dimerization domain-like
  • 57756 - Retrovirus zinc finger-like domains
  • 0Direct
    49265,49265
  • 49265 - Fibronectin type III
  • 49265 - Fibronectin type III
  • 0Direct
    47819,47819
  • 47819 - HRDC-like
  • 47819 - HRDC-like
  • 0Direct
    55781,109604
  • 55781 - GAF domain-like
  • 109604 - HD-domain/PDEase-like
  • 0Direct
    54637,52151
  • 54637 - Thioesterase/thiol ester dehydrase-isomerase
  • 52151 - FabD/lysophospholipase-like
  • 0Direct
    56784,52540
  • 56784 - HAD-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    50630,56672
  • 50630 - Acid proteases
  • 56672 - DNA/RNA polymerases
  • 0Direct
    49562,52151
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 52151 - FabD/lysophospholipase-like
  • 0Direct
    52172,52738
  • 52172 - CheY-like
  • 52738 - Methylesterase CheB, C-terminal domain
  • 0Direct
    56300,47473
  • 56300 - Metallo-dependent phosphatases
  • 47473 - EF-hand
  • 0Direct
    50044,51695
  • 50044 - SH3-domain
  • 51695 - PLC-like phosphodiesterases
  • 0Direct
    50729,56024
  • 50729 - PH domain-like
  • 56024 - Phospholipase D/nuclease
  • 0Direct
    51206,51206
  • 51206 - cAMP-binding domain-like
  • 51206 - cAMP-binding domain-like
  • 0Direct
    49879,54197
  • 49879 - SMAD/FHA domain
  • 54197 - HIT-like
  • 0Direct
    46919,53098
  • 46919 - N-terminal Zn binding domain of HIV integrase
  • 53098 - Ribonuclease H-like
  • 0Direct
    50974,50974
  • 50974 - Nitrous oxide reductase, N-terminal domain
  • 50974 - Nitrous oxide reductase, N-terminal domain
  • 0Direct
    49562,56024
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 56024 - Phospholipase D/nuclease
  • 0Direct
    53098,51283
  • 53098 - Ribonuclease H-like
  • 51283 - dUTPase-like
  • 0Direct
    56300,56300
  • 56300 - Metallo-dependent phosphatases
  • 56300 - Metallo-dependent phosphatases
  • 0Direct
    54001,53098
  • 54001 - Cysteine proteinases
  • 53098 - Ribonuclease H-like
  • 0Direct
    53098,47819
  • 53098 - Ribonuclease H-like
  • 47819 - HRDC-like
  • 0Direct
    50729,52799
  • 50729 - PH domain-like
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 0Direct
    52151,51412
  • 52151 - FabD/lysophospholipase-like
  • 51412 - Inosine monophosphate dehydrogenase (IMPDH)
  • 0Direct
    52799,56091
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 56091 - DNA ligase/mRNA capping enzyme, catalytic domain
  • 0Direct
    50156,52799
  • 50156 - PDZ domain-like
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 0Direct
    82708,53098
  • 82708 - R3H domain
  • 53098 - Ribonuclease H-like
  • 0Direct
    54236,56784
  • 54236 - Ubiquitin-like
  • 56784 - HAD-like
  • 0Direct
    50249,50249
  • 50249 - Nucleic acid-binding proteins
  • 50249 - Nucleic acid-binding proteins
  • 0Direct
    56784,56784
  • 56784 - HAD-like
  • 56784 - HAD-like
  • 0Direct
    56672,46919
  • 56672 - DNA/RNA polymerases
  • 46919 - N-terminal Zn binding domain of HIV integrase
  • 0Direct
    48726,49265
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 0.000000000000001234Direct
    54637,54637
  • 54637 - Thioesterase/thiol ester dehydrase-isomerase
  • 54637 - Thioesterase/thiol ester dehydrase-isomerase
  • 0.000000000000002108Direct
    52799,49562
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 0.00000000000001529Direct
    64268,50729
  • 64268 - PX domain
  • 50729 - PH domain-like
  • 0.0000000000128Direct
    53474,53474
  • 53474 - alpha/beta-Hydrolases
  • 53474 - alpha/beta-Hydrolases
  • 0.0000000000399Direct
    56300,55816
  • 56300 - Metallo-dependent phosphatases
  • 55816 - 5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain
  • 0.00000000005099Direct
    54236,47031
  • 54236 - Ubiquitin-like
  • 47031 - Second domain of FERM
  • 0.0000000003968Direct
    55073,141868
  • 55073 - Nucleotide cyclase
  • 141868 - EAL domain-like
  • 0.000000003494Direct
    47031,50729
  • 47031 - Second domain of FERM
  • 50729 - PH domain-like
  • 0.00000001088Direct
    63748,50199
  • 63748 - Tudor/PWWP/MBT
  • 50199 - Staphylococcal nuclease
  • 0.00000002599Direct
    56024,56024
  • 56024 - Phospholipase D/nuclease
  • 56024 - Phospholipase D/nuclease
  • 0.00000004574Direct
    100950,100950
  • 100950 - NagB/RpiA/CoA transferase-like
  • 100950 - NagB/RpiA/CoA transferase-like
  • 0.0000007611Direct
    81301,81271
  • 81301 - Nucleotidyltransferase
  • 81271 - TGS-like
  • 0.000004686Direct
    109604,81301
  • 109604 - HD-domain/PDEase-like
  • 81301 - Nucleotidyltransferase
  • 0.000004796Direct
    47336,53474
  • 47336 - ACP-like
  • 53474 - alpha/beta-Hydrolases
  • 0.000009295Direct
    53335,52949
  • 53335 - S-adenosyl-L-methionine-dependent methyltransferases
  • 52949 - Macro domain-like
  • 0.00007482Direct
    53474,53335
  • 53474 - alpha/beta-Hydrolases
  • 53335 - S-adenosyl-L-methionine-dependent methyltransferases
  • 0.0002044Direct
    53756,56784
  • 53756 - UDP-Glycosyltransferase/glycogen phosphorylase
  • 56784 - HAD-like
  • 0.001663Inherited
    54236,54236
  • 54236 - Ubiquitin-like
  • 54236 - Ubiquitin-like
  • 0.002288Inherited
    53774,48403
  • 53774 - Glutaminase/Asparaginase
  • 48403 - Ankyrin repeat
  • 0.00908Inherited
    51735,51735
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 0.01112Inherited
    57756,51283
  • 57756 - Retrovirus zinc finger-like domains
  • 51283 - dUTPase-like
  • 0.01634Inherited
    51283,50630
  • 51283 - dUTPase-like
  • 50630 - Acid proteases
  • 0.01634Inherited
    51735,47336
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 47336 - ACP-like
  • 0.02068Inherited
    52058,52058
  • 52058 - L domain-like
  • 52058 - L domain-like
  • 0.03873Inherited
    48726,48726
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 0.04503Inherited
    57756,57756
  • 57756 - Retrovirus zinc finger-like domains
  • 57756 - Retrovirus zinc finger-like domains
  • 0.1266Inherited
    53098,56672
  • 53098 - Ribonuclease H-like
  • 56672 - DNA/RNA polymerases
  • 0.1421Inherited
    52151,55048
  • 52151 - FabD/lysophospholipase-like
  • 55048 - Probable ACP-binding domain of malonyl-CoA ACP transacylase
  • 0.1957Inherited
    52540,52540
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 1Inherited
    53901,53901
  • 53901 - Thiolase-like
  • 53901 - Thiolase-like
  • 1Inherited
    50129,51735
  • 50129 - GroES-like
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 1Inherited
    54211,54211
  • 54211 - Ribosomal protein S5 domain 2-like
  • 54211 - Ribosomal protein S5 domain 2-like
  • 1Inherited
    56091,50249
  • 56091 - DNA ligase/mRNA capping enzyme, catalytic domain
  • 50249 - Nucleic acid-binding proteins
  • 1Inherited
    48239,48576
  • 48239 - Terpenoid cyclases/Protein prenyltransferases
  • 48576 - Terpenoid synthases
  • 1Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    55781,55781,55781
  • 55781 - GAF domain-like
  • 55781 - GAF domain-like
  • 55781 - GAF domain-like
  • 0Direct
    56672,46919,53098
  • 56672 - DNA/RNA polymerases
  • 46919 - N-terminal Zn binding domain of HIV integrase
  • 53098 - Ribonuclease H-like
  • 0Direct
    49899,48726,49265
  • 49899 - Concanavalin A-like lectins/glucanases
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 0Direct
    56024,56024,56024
  • 56024 - Phospholipase D/nuclease
  • 56024 - Phospholipase D/nuclease
  • 56024 - Phospholipase D/nuclease
  • 0Direct
    69065,69065,54768
  • 69065 - RNase III domain-like
  • 69065 - RNase III domain-like
  • 54768 - dsRNA-binding domain-like
  • 0Direct
    55550,50044,51695
  • 55550 - SH2 domain
  • 50044 - SH3-domain
  • 51695 - PLC-like phosphodiesterases
  • 0Direct
    50044,51695,49562
  • 50044 - SH3-domain
  • 51695 - PLC-like phosphodiesterases
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 0Direct
    50729,56024,56024
  • 50729 - PH domain-like
  • 56024 - Phospholipase D/nuclease
  • 56024 - Phospholipase D/nuclease
  • 0Direct
    50199,50199,50199
  • 50199 - Staphylococcal nuclease
  • 50199 - Staphylococcal nuclease
  • 50199 - Staphylococcal nuclease
  • 0Direct
    81324,52799,49562
  • 81324 - Voltage-gated potassium channels
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 0Direct
    56672,53098,51283
  • 56672 - DNA/RNA polymerases
  • 53098 - Ribonuclease H-like
  • 51283 - dUTPase-like
  • 0Direct
    51283,50630,56672
  • 51283 - dUTPase-like
  • 50630 - Acid proteases
  • 56672 - DNA/RNA polymerases
  • 0Direct
    56568,47233,52799
  • 56568 - Non-globular alpha+beta subunits of globular proteins
  • 47233 - Bacterial GAP domain
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 0Direct
    82708,53098,54928
  • 82708 - R3H domain
  • 53098 - Ribonuclease H-like
  • 54928 - RNA-binding domain, RBD
  • 0Direct
    49265,49265,49265
  • 49265 - Fibronectin type III
  • 49265 - Fibronectin type III
  • 49265 - Fibronectin type III
  • 0Direct
    55781,55781,109604
  • 55781 - GAF domain-like
  • 55781 - GAF domain-like
  • 109604 - HD-domain/PDEase-like
  • 0Direct
    50630,56672,53098
  • 50630 - Acid proteases
  • 56672 - DNA/RNA polymerases
  • 53098 - Ribonuclease H-like
  • 0Direct
    56784,54211,54211
  • 56784 - HAD-like
  • 54211 - Ribosomal protein S5 domain 2-like
  • 54211 - Ribosomal protein S5 domain 2-like
  • 0Direct
    47836,47943,47353
  • 47836 - Retroviral matrix proteins
  • 47943 - Retrovirus capsid protein, N-terminal core domain
  • 47353 - Retrovirus capsid dimerization domain-like
  • 0Direct
    46938,52087,52799
  • 46938 - CRAL/TRIO N-terminal domain
  • 52087 - CRAL/TRIO domain
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 0Direct
    52799,56091,50249
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 56091 - DNA ligase/mRNA capping enzyme, catalytic domain
  • 50249 - Nucleic acid-binding proteins
  • 0Direct
    47353,57756,50630
  • 47353 - Retrovirus capsid dimerization domain-like
  • 57756 - Retrovirus zinc finger-like domains
  • 50630 - Acid proteases
  • 0Direct
    50630,56672,46919
  • 50630 - Acid proteases
  • 56672 - DNA/RNA polymerases
  • 46919 - N-terminal Zn binding domain of HIV integrase
  • 0Direct
    55550,55550,50044
  • 55550 - SH2 domain
  • 55550 - SH2 domain
  • 50044 - SH3-domain
  • 0Direct
    56672,53098,50122
  • 56672 - DNA/RNA polymerases
  • 53098 - Ribonuclease H-like
  • 50122 - DNA-binding domain of retroviral integrase
  • 0Direct
    56672,53098,46919
  • 56672 - DNA/RNA polymerases
  • 53098 - Ribonuclease H-like
  • 46919 - N-terminal Zn binding domain of HIV integrase
  • 0Direct
    50199,63748,50199
  • 50199 - Staphylococcal nuclease
  • 63748 - Tudor/PWWP/MBT
  • 50199 - Staphylococcal nuclease
  • 0Direct
    90188,53649,54060
  • 90188 - Somatomedin B domain
  • 53649 - Alkaline phosphatase-like
  • 54060 - His-Me finger endonucleases
  • 0Direct
    46919,53098,50122
  • 46919 - N-terminal Zn binding domain of HIV integrase
  • 53098 - Ribonuclease H-like
  • 50122 - DNA-binding domain of retroviral integrase
  • 0Direct
    54637,54637,55961
  • 54637 - Thioesterase/thiol ester dehydrase-isomerase
  • 54637 - Thioesterase/thiol ester dehydrase-isomerase
  • 55961 - Bet v1-like
  • 0Direct
    47943,47353,57756
  • 47943 - Retrovirus capsid protein, N-terminal core domain
  • 47353 - Retrovirus capsid dimerization domain-like
  • 57756 - Retrovirus zinc finger-like domains
  • 0Direct
    90188,90188,53649
  • 90188 - Somatomedin B domain
  • 90188 - Somatomedin B domain
  • 53649 - Alkaline phosphatase-like
  • 0Direct
    53098,51283,46919
  • 53098 - Ribonuclease H-like
  • 51283 - dUTPase-like
  • 46919 - N-terminal Zn binding domain of HIV integrase
  • 0Direct
    56672,53098,53098
  • 56672 - DNA/RNA polymerases
  • 53098 - Ribonuclease H-like
  • 53098 - Ribonuclease H-like
  • 0Direct
    50729,47473,51695
  • 50729 - PH domain-like
  • 47473 - EF-hand
  • 51695 - PLC-like phosphodiesterases
  • 0Direct
    51283,46919,53098
  • 51283 - dUTPase-like
  • 46919 - N-terminal Zn binding domain of HIV integrase
  • 53098 - Ribonuclease H-like
  • 0Direct
    57756,50630,56672
  • 57756 - Retrovirus zinc finger-like domains
  • 50630 - Acid proteases
  • 56672 - DNA/RNA polymerases
  • 0Direct
    64268,50729,56024
  • 64268 - PX domain
  • 50729 - PH domain-like
  • 56024 - Phospholipase D/nuclease
  • 0Direct
    50199,50199,63748
  • 50199 - Staphylococcal nuclease
  • 50199 - Staphylococcal nuclease
  • 63748 - Tudor/PWWP/MBT
  • 0Direct
    49562,54236,54236
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 54236 - Ubiquitin-like
  • 54236 - Ubiquitin-like
  • 0Direct
    53098,47819,47819
  • 53098 - Ribonuclease H-like
  • 47819 - HRDC-like
  • 47819 - HRDC-like
  • 0Direct
    53098,46919,53098
  • 53098 - Ribonuclease H-like
  • 46919 - N-terminal Zn binding domain of HIV integrase
  • 53098 - Ribonuclease H-like
  • 0Direct
    55550,55550,52799
  • 55550 - SH2 domain
  • 55550 - SH2 domain
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 0Direct
    47473,51695,49562
  • 47473 - EF-hand
  • 51695 - PLC-like phosphodiesterases
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 0Direct
    48726,49265,49265
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 49265 - Fibronectin type III
  • 0.00000000000001546Direct
    54236,47031,50729
  • 54236 - Ubiquitin-like
  • 47031 - Second domain of FERM
  • 50729 - PH domain-like
  • 0.0000000003968Direct
    48726,48726,49265
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 0.000000009397Direct
    51735,47336,53474
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 47336 - ACP-like
  • 53474 - alpha/beta-Hydrolases
  • 0.00000005763Direct
    109604,81301,81271
  • 109604 - HD-domain/PDEase-like
  • 81301 - Nucleotidyltransferase
  • 81271 - TGS-like
  • 0.000004686Direct
    50129,51735,51735
  • 50129 - GroES-like
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 0.0003636Direct
    48726,48726,48726
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 0.004191Inherited
    51735,51735,47336
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 47336 - ACP-like
  • 0.01374Inherited
    57756,51283,50630
  • 57756 - Retrovirus zinc finger-like domains
  • 51283 - dUTPase-like
  • 50630 - Acid proteases
  • 0.01634Inherited
    47353,57756,57756
  • 47353 - Retrovirus capsid dimerization domain-like
  • 57756 - Retrovirus zinc finger-like domains
  • 57756 - Retrovirus zinc finger-like domains
  • 0.02755Inherited
    57756,57756,51283
  • 57756 - Retrovirus zinc finger-like domains
  • 57756 - Retrovirus zinc finger-like domains
  • 51283 - dUTPase-like
  • 0.02755Inherited


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