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Enzyme Commission (EC): Acting on peptide bonds (peptidases)

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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Root: EC Hierarchy (from IntEnz release 70)

Shortest distance to current term (+ for parents, - for children) EC term [EC ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + 2:   root [root] <7>
+ 1:   Hydrolases [3] <13>(395|668) (394|418|206)
0:   Acting on peptide bonds (peptidases) [3.4] <19>(114|168) (114|130|72)
- 1:   Serine endopeptidases [3.4.21] <121>(40|45) (40|48|34)
- 1:   Metalloendopeptidases [3.4.24] <89>(19|30) (19|17|9)
- 1:   Cysteine endopeptidases [3.4.22] <71>(24|30) (24|22|12)
- 1:   Aspartic endopeptidases [3.4.23] <52>(11|13) (11|9|8)
- 1:   Endopeptidases of unknown catalytic mechanism [3.4.99] <46>(0|0) (0|0|0)
- 1:   Aminopeptidases [3.4.11] <27>(14|15) (14|11|3)
- 1:   Peptidyl peptide hydrolases [3.4.4] <25>(0|0) (0|0|0)
- 1:   Metallocarboxypeptidases [3.4.17] <24>(8|10) (8|6|3)
- 1:   Dipeptidases [3.4.13] <22>(6|6) (6|1|0)
- 1:   Omega peptidases [3.4.19] <16>(32|30) (32|24|5)
- 1:   Dipeptidyl-peptidases and tripeptidyl-peptidases [3.4.14] <13>(8|9) (8|5|1)
- 1:   Peptidylamino-acid hydrolases or acylamino-acid hydrolases [3.4.12] <13>(0|0) (0|0|0)
- 1:   Dipeptide hydrolases [3.4.3] <7>(0|0) (0|0|0)
- 1:   Peptidyl-dipeptidases [3.4.15] <6>(2|1) (2|0|0)
- 1:   Serine-type carboxypeptidases [3.4.16] <6>(5|6) (5|3|0)
- 1:   alpha-Amino-acyl-peptide hydrolases [3.4.1] <4>(0|0) (0|0|0)
- 1:   Peptidyl-amino-acid hydrolases [3.4.2] <3>(0|0) (0|0|0)
- 1:   Threonine endopeptidases [3.4.25] <2>(1|1) (1|0|0)
- 1:   Cysteine-type carboxypeptidases [3.4.18] <1>(1|1) (1|0|0)


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Superfamily

(show details)
SCOP termFDR (all)Annotation (direct or inherited)
Replicase NSP90Direct
EndoU-like0Direct
Cap-Gly domain0Direct
STI-like0Direct
LD-carboxypeptidase A C-terminal domain-like0Direct
LDL receptor-like module0Direct
DPP6 N-terminal domain-like0Direct
TMV-like viral coat proteins0Direct
SARS Nsp1-like0Direct
Macro domain-like0Direct
Retrovirus zinc finger-like domains0Direct
LexA/Signal peptidase0Direct
Pyrrolidone carboxyl peptidase (pyroglutamate aminopeptidase)0Direct
X-Prolyl dipeptidyl aminopeptidase PepX, N-terminal domain0Direct
TSP-1 type 1 repeat0Direct
Acid proteases0Direct
"Winged helix" DNA-binding domain0Direct
Creatinase/prolidase N-terminal domain0Direct
Viral glycoprotein, central and dimerisation domains0Direct
Soluble domain of poliovirus core protein 3a0Direct
Caspase-like0Direct
E set domains0Direct
Leukotriene A4 hydrolase N-terminal domain0Direct
Positive stranded ssRNA viruses0Direct
Penicillin binding protein dimerisation domain0Direct
Cystatin/monellin0Direct
Dipeptidyl peptidase I (cathepsin C), exclusion domain0Direct
Cysteine proteinases0Direct
Flavivirus capsid protein C0Direct
Coronavirus NSP10-like0Direct
Zn-dependent exopeptidases0Direct
Creatinase/aminopeptidase0Direct
Coronavirus NSP7-like0Direct
NSP3A-like0Direct
N-terminal nucleophile aminohydrolases (Ntn hydrolases)0Direct
DNA/RNA polymerases0Direct
Sec-C motif0Direct
Kringle-like0Direct
Retroviral matrix proteins0Direct
Protease propeptides/inhibitors0Direct
Complement control module/SCR domain0Direct
Herpes virus serine proteinase, assemblin0Direct
Calpain large subunit, middle domain (domain III)0Direct
EGF/Laminin0Direct
PDZ domain-like0Direct
Collagen-binding domain0Direct
Subtilisin-like0Direct
Retrovirus capsid dimerization domain-like0Direct
Sortase0Direct
Rhomboid-like0Direct
PUA domain-like0Direct
DUSP-like0Direct
Spermadhesin, CUB domain0Direct
ClpP/crotonase0Direct
N-terminal Zn binding domain of HIV integrase0Direct
Carboxypeptidase regulatory domain-like0Direct
DNA-binding domain of retroviral integrase0Direct
D-aminopeptidase, middle and C-terminal domains0Direct
Trypsin-like serine proteases0Direct
HybD-like0Direct
Aminopeptidase/glucanase lid domain0Direct
DEATH domain0Direct
Metalloproteases ("zincins"), catalytic domain0Direct
Penicillin-binding protein associated domain0Direct
alpha/beta-Hydrolases0Direct
Viral leader polypeptide zinc finger0Direct
Hedgehog/DD-peptidase0Direct
SEA domain0Direct
Kazal-type serine protease inhibitors0Direct
Hairpin loop containing domain-like0Direct
Peptidase/esterase 'gauge' domain0Direct
OMPT-like0Direct
GLA-domain0Direct
Retrovirus capsid protein, N-terminal core domain0Direct
Transferrin receptor-like dimerisation domain0Direct
PGBD-like0Direct
PA domain0Direct
Coronavirus NSP8-like0Direct
Clostridium neurotoxins, "coiled-coil" domain0Direct
Blood coagulation inhibitor (disintegrin)0Direct
Hemopexin-like domain0Direct
Ubiquitin-like2.561e-16Direct
LuxS/MPP-like metallohydrolase0.000000000000004988Direct
SRCR-like0.0000000000009563Direct
TRAF domain-like0.00000000001881Direct
HIT/MYND zinc finger-like0.00000000002144Direct
FnI-like domain0.00000000006655Direct
UBA-like0.000000000197Direct
beta-Roll0.000000001891Direct
Duplicated hybrid motif0.000000003345Direct
EF-hand0.0000002306Direct
Ran binding protein zinc finger-like0.0000002489Direct
Bacterial exopeptidase dimerisation domain0.000002678Direct
beta-lactamase/transpeptidase-like0.0000032Direct
PKD domain0.000006232Direct
Growth factor receptor domain0.00001186Direct
Ribosomal protein S5 domain 2-like0.00004913Direct
Autotransporter0.0001519Direct
JAB1/MPN domain0.001168Inherited
RING/U-box0.003926Inherited
Ribonuclease Rh-like0.004714Inherited
HSP20-like chaperones0.006676Inherited
ARM repeat0.0107Inherited
vWA-like0.02333Inherited
Galactose-binding domain-like0.03407Inherited
Rhodanese/Cell cycle control phosphatase0.6113Inherited
Lysozyme-like0.944Inherited
Concanavalin A-like lectins/glucanases1Inherited
Ribonuclease H-like1Inherited
P-loop containing nucleoside triphosphate hydrolases1Inherited
Class I glutamine amidotransferase-like1Inherited
Pectin lyase-like1Inherited
Metallo-dependent hydrolases1Inherited
S-adenosyl-L-methionine-dependent methyltransferases1Inherited


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Family

(show details)
SCOP termFDR (all)Annotation (direct or inherited)
Zf-UBP0Direct
Retrovirus zinc finger-like domains0Direct
Coronavirus NSP7-like0Direct
Adenain-like0Direct
Viral cysteine protease of trypsin fold0Direct
Dac-like0Direct
PBP transglycosylase domain-like0Direct
Cap-Gly domain0Direct
Proteasome subunits0Direct
Calpain large subunit, catalytic domain (domain II)0Direct
TNF-alpha converting enzyme, TACE, catalytic domain0Direct
Calpain large subunit, middle domain (domain III)0Direct
Nodaviridae-like VP0Direct
MPP-like0Direct
Serralysin-like metalloprotease, catalytic (N-terminal) domain0Direct
Caliciviridae-like VP0Direct
MMP N-terminal domain0Direct
Picornaviridae-like VP (VP1, VP2, VP3 and VP4)0Direct
RNA-dependent RNA-polymerase0Direct
Pepsin-like0Direct
FolH catalytic domain-like0Direct
Pancreatic carboxypeptidase, activation domain0Direct
Papain-like0Direct
TSP-1 type 1 repeat0Direct
Retroviral protease (retropepsin)0Direct
Leishmanolysin0Direct
Gingipain R (RgpB), N-terminal domain0Direct
Prolyl oligopeptidase, N-terminal domain0Direct
Staphopain B, prodomain0Direct
Transferrin receptor-like dimerisation domain0Direct
MATH domain0Direct
Ubiquitin carboxyl-terminal hydrolase UCH-L0Direct
Leukotriene A4 hydrolase catalytic domain0Direct
Serine carboxypeptidase-like0Direct
Pyrrolidone carboxyl peptidase (pyroglutamate aminopeptidase)0Direct
Sec-C motif0Direct
Class II viral fusion proteins C-terminal domain0Direct
Blood coagulation inhibitor (disintegrin)0Direct
SARS Nsp1-like0Direct
Leucine aminopeptidase, C-terminal domain0Direct
Replicase NSP90Direct
Proprotein convertase P-domain0Direct
Flavivirus capsid protein C0Direct
PKD domain0Direct
Clostridium neurotoxins, the second last domain0Direct
DEATH effector domain, DED0Direct
Leucine aminopeptidase (Aminopeptidase A), N-terminal domain0Direct
Subtilases0Direct
DPP6 N-terminal domain-like0Direct
Type 1 signal peptidase0Direct
Reprolysin-like0Direct
Pancreatic carboxypeptidases0Direct
NSP3A-like0Direct
Prokaryotic proteases0Direct
Spermadhesin, CUB domain0Direct
Viral leader polypeptide zinc finger0Direct
Neurolysin-like0Direct
NlpC/P600Direct
Serine-carboxyl proteinase, SCP0Direct
HtrA-like serine proteases0Direct
EGF-type module0Direct
Clp protease, ClpP subunit0Direct
PepX catalytic domain-like0Direct
Immunodeficiency virus matrix proteins0Direct
RNA helicase0Direct
Soluble domain of poliovirus core protein 3a0Direct
Carboxypeptidase T0Direct
FMDV leader protease0Direct
Gamma-glutamyltranspeptidase-like0Direct
Clostridium neurotoxins, catalytic domain0Direct
Astacin0Direct
ATP-dependent protease Lon (La), catalytic domain0Direct
LD-carboxypeptidase A N-terminal domain-like0Direct
LON domain-like0Direct
Hepsin, N-terminal domain0Direct
Tail specific protease, catalytic domain0Direct
Caspase recruitment domain, CARD0Direct
Viral proteases0Direct
Caspase catalytic domain0Direct
Fibronectin type II module0Direct
DNA-binding domain of retroviral integrase0Direct
Integrin A (or I) domain0Direct
Ubiquitin thiolesterase protein OTUB2 (Otubain-2)0Direct
PA domain0Direct
PepX C-terminal domain-like0Direct
SEA domain0Direct
Gingipain R (RgpB), C-terminal domain0Direct
Retrovirus capsid protein C-terminal domain0Direct
Herpes virus serine proteinase, assemblin0Direct
Thermolysin-like0Direct
Proline iminopeptidase-like0Direct
Penta-EF-hand proteins0Direct
Sortase0Direct
Fibronectin type I module0Direct
LD-carboxypeptidase A C-terminal domain-like0Direct
DUSP, domain in ubiquitin-specific proteases0Direct
Outer membrane protease OMPT0Direct
GLA-domain0Direct
LexA repressor, N-terminal DNA-binding domain0Direct
VanX-like0Direct
Carboxypeptidase regulatory domain0Direct
Eukaryotic proteases0Direct
Clostridium neurotoxins, "coiled-coil" domain0Direct
Collagen-binding domain0Direct
D-aminopeptidase, middle and C-terminal domains0Direct
Kringle modules0Direct
Clostridium neurotoxins, C-terminal domain0Direct
Creatinase/prolidase N-terminal domain0Direct
Hemopexin-like domain0Direct
Rhomboid-like0Direct
Creatinase/aminopeptidase0Direct
Methionine aminopeptidase, insert domain0Direct
Aspartyl dipeptidase PepE0Direct
X-Prolyl dipeptidyl aminopeptidase PepX, N-terminal domain0Direct
Matrix metalloproteases, catalytic domain0Direct
Prohormone convertase 1 pro-domain0Direct
Nsp15 N-terminal domain-like0Direct
N-terminal Zn binding domain of HIV integrase0Direct
Virulence factor P.69 pertactin0Direct
Aminopeptidase/glucanase lid domain0Direct
Subtilase propeptides/inhibitors0Direct
TMV-like viral coat proteins0Direct
PBP5 C-terminal domain-like0Direct
beta-Lactamase/D-ala carboxypeptidase0Direct
DPP6 catalytic domain-like0Direct
M48USP-like0Direct
Penicillin binding protein dimerisation domain0Direct
Renal dipeptidase0Direct
Neutral endopeptidase (neprilysin)0Direct
Acylamino-acid-releasing enzyme, C-terminal donain0Direct
Zinc protease0Direct
LexA-related0Direct
LDL receptor-like module0Direct
Prolyl oligopeptidase, C-terminal domain0Direct
Nsp15 C-terminal domain-like0Direct
Coronavirus NSP8-like0Direct
Fungal zinc peptidase0Direct
Coronavirus NSP10-like0Direct
Germination protease0Direct
Complement control module/SCR domain0Direct
Ubiquitin carboxyl-terminal hydrolase, UCH0Direct
Viral glycoprotein, central and dimerisation domains0Direct
Retrovirus capsid protein, N-terminal core domain0Direct
Dipeptidyl peptidase I (cathepsin C), exclusion domain0Direct
mRNA cap methylase0Direct
Leukotriene A4 hydrolase N-terminal domain0.000000000000003994Direct
Peptidoglycan hydrolase LytM0.0000000000001398Direct
Reverse transcriptase0.0000000000002612Direct
Macro domain0.0000000000002803Direct
Bacterial dinuclear zinc exopeptidases0.0000000002329Direct
MYND zinc finger0.0000000007952Direct
Serralysin-like metalloprotease, C-terminal domain0.000000002494Direct
Retroviral integrase, catalytic domain0.00000001616Direct
UBA domain0.00000007481Direct
(Glycosyl)asparaginase0.0000001337Direct
Ran binding protein zinc finger-like0.0000003159Direct
GS domain0.000002112Direct
Anthrax toxin lethal factor, N- and C-terminal domains0.000002112Direct
Ubiquitin-related0.000002646Direct
Bacterial exopeptidase dimerisation domain0.00002152Direct
Scavenger receptor cysteine-rich (SRCR) domain0.0000461Direct
MAM domain0.0002107Direct
Growth factor receptor domain0.001339Inherited
Ribonuclease Rh-like0.005266Inherited
Extended AAA-ATPase domain0.1353Inherited
Leukotriene A4 hydrolase C-terminal domain0.7368Inherited
Class I glutamine amidotransferases (GAT)1Inherited
Ribonuclease H1Inherited


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Supra-domain (including individual superfamily)

(show details)
Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Creatinase/aminopeptidase0Direct
Coronavirus NSP7-like0Direct
GLA-domain0Direct
alpha/beta-Hydrolases0Direct
ClpP/crotonase0Direct
Hedgehog/DD-peptidase0Direct
Calpain large subunit, middle domain (domain III)0Direct
Herpes virus serine proteinase, assemblin0Direct
Leukotriene A4 hydrolase N-terminal domain0Direct
Sec-C motif0Direct
PUA domain-like0Direct
Blood coagulation inhibitor (disintegrin)0Direct
Subtilisin-like0Direct
N-terminal nucleophile aminohydrolases (Ntn hydrolases)0Direct
HybD-like0Direct
Penicillin binding protein dimerisation domain0Direct
DNA-binding domain of retroviral integrase0Direct
NSP3A-like0Direct
Cystatin/monellin0Direct
Positive stranded ssRNA viruses0Direct
Sortase0Direct
Cap-Gly domain0Direct
Retroviral matrix proteins0Direct
N-terminal Zn binding domain of HIV integrase0Direct
Retrovirus capsid dimerization domain-like0Direct
Penicillin-binding protein associated domain0Direct
D-aminopeptidase, middle and C-terminal domains0Direct
OMPT-like0Direct
Replicase NSP90Direct
Spermadhesin, CUB domain0Direct
DEATH domain0Direct
Dipeptidyl peptidase I (cathepsin C), exclusion domain0Direct
PGBD-like0Direct
Transferrin receptor-like dimerisation domain0Direct
Macro domain-like0Direct
Collagen-binding domain0Direct
SEA domain0Direct
Cysteine proteinases0Direct
EGF/Laminin0Direct
TSP-1 type 1 repeat0Direct
Peptidase/esterase 'gauge' domain0Direct
PA domain0Direct
Viral glycoprotein, central and dimerisation domains0Direct
Kazal-type serine protease inhibitors0Direct
Coronavirus NSP8-like0Direct
Acid proteases0Direct
Creatinase/prolidase N-terminal domain0Direct
DNA/RNA polymerases0Direct
Retrovirus zinc finger-like domains0Direct
Clostridium neurotoxins, "coiled-coil" domain0Direct
DUSP-like0Direct
PDZ domain-like0Direct
SARS Nsp1-like0Direct
Viral leader polypeptide zinc finger0Direct
Pyrrolidone carboxyl peptidase (pyroglutamate aminopeptidase)0Direct
LD-carboxypeptidase A C-terminal domain-like0Direct
LDL receptor-like module0Direct
Aminopeptidase/glucanase lid domain0Direct
Trypsin-like serine proteases0Direct
Zn-dependent exopeptidases0Direct
Flavivirus capsid protein C0Direct
Complement control module/SCR domain0Direct
Carboxypeptidase regulatory domain-like0Direct
Coronavirus NSP10-like0Direct
TMV-like viral coat proteins0Direct
Hairpin loop containing domain-like0Direct
EndoU-like0Direct
Rhomboid-like0Direct
Soluble domain of poliovirus core protein 3a0Direct
Kringle-like0Direct
"Winged helix" DNA-binding domain0Direct
Retrovirus capsid protein, N-terminal core domain0Direct
X-Prolyl dipeptidyl aminopeptidase PepX, N-terminal domain0Direct
Caspase-like0Direct
LexA/Signal peptidase0Direct
Metalloproteases ("zincins"), catalytic domain0Direct
Hemopexin-like domain0Direct
DPP6 N-terminal domain-like0Direct
Protease propeptides/inhibitors0Direct
E set domains0Direct
STI-like0Direct
Ubiquitin-like1.777e-16Direct
LuxS/MPP-like metallohydrolase0.0000000000000035Direct
SRCR-like0.0000000000006876Direct
TRAF domain-like0.00000000001368Direct
HIT/MYND zinc finger-like0.00000000001562Direct
FnI-like domain0.00000000004879Direct
UBA-like0.0000000001456Direct
beta-Roll0.000000001414Direct
Duplicated hybrid motif0.000000002513Direct
EF-hand0.0000001778Direct
Ran binding protein zinc finger-like0.000000192Direct
Bacterial exopeptidase dimerisation domain0.000002102Direct
beta-lactamase/transpeptidase-like0.000002517Direct
PKD domain0.00000491Direct
Growth factor receptor domain0.000009409Direct
Ribosomal protein S5 domain 2-like0.00003941Direct
Autotransporter0.0001232Direct
JAB1/MPN domain0.0009659Direct
RING/U-box0.003291Inherited
Ribonuclease Rh-like0.003957Inherited
HSP20-like chaperones0.005633Inherited
ARM repeat0.00908Inherited
vWA-like0.01999Inherited
Galactose-binding domain-like0.02931Inherited
Rhodanese/Cell cycle control phosphatase0.5613Inherited
Lysozyme-like0.8731Inherited
Concanavalin A-like lectins/glucanases1Inherited
Metallo-dependent hydrolases1Inherited
P-loop containing nucleoside triphosphate hydrolases1Inherited
Class I glutamine amidotransferase-like1Inherited
Ribonuclease H-like1Inherited
S-adenosyl-L-methionine-dependent methyltransferases1Inherited
Pectin lyase-like1Inherited

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
46785,51306
  • 46785 - "Winged helix" DNA-binding domain
  • 51306 - LexA/Signal peptidase
  • 0Direct
    56519,56601
  • 56519 - Penicillin binding protein dimerisation domain
  • 56601 - beta-lactamase/transpeptidase-like
  • 0Direct
    53474,49785
  • 53474 - alpha/beta-Hydrolases
  • 49785 - Galactose-binding domain-like
  • 0Direct
    49599,54001
  • 49599 - TRAF domain-like
  • 54001 - Cysteine proteinases
  • 0Direct
    159936,53335
  • 159936 - NSP3A-like
  • 53335 - S-adenosyl-L-methionine-dependent methyltransferases
  • 0Direct
    82671,57424
  • 82671 - SEA domain
  • 57424 - LDL receptor-like module
  • 0Direct
    47473,144091
  • 47473 - EF-hand
  • 144091 - Rhomboid-like
  • 0Direct
    57424,49854
  • 57424 - LDL receptor-like module
  • 49854 - Spermadhesin, CUB domain
  • 0Direct
    54236,54001
  • 54236 - Ubiquitin-like
  • 54001 - Cysteine proteinases
  • 0Direct
    54001,88633
  • 54001 - Cysteine proteinases
  • 88633 - Positive stranded ssRNA viruses
  • 0Direct
    57184,50494
  • 57184 - Growth factor receptor domain
  • 50494 - Trypsin-like serine proteases
  • 0Direct
    50494,52540
  • 50494 - Trypsin-like serine proteases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    55486,82895
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 82895 - TSP-1 type 1 repeat
  • 0Direct
    50156,52096
  • 50156 - PDZ domain-like
  • 52096 - ClpP/crotonase
  • 0Direct
    49899,50386
  • 49899 - Concanavalin A-like lectins/glucanases
  • 50386 - STI-like
  • 0Direct
    49854,57535
  • 49854 - Spermadhesin, CUB domain
  • 57535 - Complement control module/SCR domain
  • 0Direct
    49899,49599
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49599 - TRAF domain-like
  • 0Direct
    55486,57552
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 57552 - Blood coagulation inhibitor (disintegrin)
  • 0Direct
    63411,63411
  • 63411 - LuxS/MPP-like metallohydrolase
  • 63411 - LuxS/MPP-like metallohydrolase
  • 0Direct
    57630,57184
  • 57630 - GLA-domain
  • 57184 - Growth factor receptor domain
  • 0Direct
    53955,56601
  • 53955 - Lysozyme-like
  • 56601 - beta-lactamase/transpeptidase-like
  • 0Direct
    57440,57440
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 0Direct
    57440,57196
  • 57440 - Kringle-like
  • 57196 - EGF/Laminin
  • 0Direct
    50494,50156
  • 50494 - Trypsin-like serine proteases
  • 50156 - PDZ domain-like
  • 0Direct
    49854,57196
  • 49854 - Spermadhesin, CUB domain
  • 57196 - EGF/Laminin
  • 0Direct
    53187,49464
  • 53187 - Zn-dependent exopeptidases
  • 49464 - Carboxypeptidase regulatory domain-like
  • 0Direct
    47353,57756
  • 47353 - Retrovirus capsid dimerization domain-like
  • 57756 - Retrovirus zinc finger-like domains
  • 0Direct
    53300,50494
  • 53300 - vWA-like
  • 50494 - Trypsin-like serine proteases
  • 0Direct
    74924,74924
  • 74924 - Cap-Gly domain
  • 74924 - Cap-Gly domain
  • 0Direct
    54001,143791
  • 54001 - Cysteine proteinases
  • 143791 - DUSP-like
  • 0Direct
    52025,53187
  • 52025 - PA domain
  • 53187 - Zn-dependent exopeptidases
  • 0Direct
    55486,58091
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 58091 - Clostridium neurotoxins, "coiled-coil" domain
  • 0Direct
    88633,88633
  • 88633 - Positive stranded ssRNA viruses
  • 88633 - Positive stranded ssRNA viruses
  • 0Direct
    49854,57424
  • 49854 - Spermadhesin, CUB domain
  • 57424 - LDL receptor-like module
  • 0Direct
    75001,54001
  • 75001 - Dipeptidyl peptidase I (cathepsin C), exclusion domain
  • 54001 - Cysteine proteinases
  • 0Direct
    55486,57440
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 57440 - Kringle-like
  • 0Direct
    54001,55205
  • 54001 - Cysteine proteinases
  • 55205 - EPT/RTPC-like
  • 0Direct
    52317,141986
  • 52317 - Class I glutamine amidotransferase-like
  • 141986 - LD-carboxypeptidase A C-terminal domain-like
  • 0Direct
    55486,50923
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 50923 - Hemopexin-like domain
  • 0Direct
    89043,50494
  • 89043 - Soluble domain of poliovirus core protein 3a
  • 50494 - Trypsin-like serine proteases
  • 0Direct
    55486,49899
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0Direct
    54897,52743
  • 54897 - Protease propeptides/inhibitors
  • 52743 - Subtilisin-like
  • 0Direct
    54403,54001
  • 54403 - Cystatin/monellin
  • 54001 - Cysteine proteinases
  • 0Direct
    50993,53474
  • 50993 - Peptidase/esterase 'gauge' domain
  • 53474 - alpha/beta-Hydrolases
  • 0Direct
    47943,47353
  • 47943 - Retrovirus capsid protein, N-terminal core domain
  • 47353 - Retrovirus capsid dimerization domain-like
  • 0Direct
    88633,50494
  • 88633 - Positive stranded ssRNA viruses
  • 50494 - Trypsin-like serine proteases
  • 0Direct
    54001,46934
  • 54001 - Cysteine proteinases
  • 46934 - UBA-like
  • 0Direct
    82895,82895
  • 82895 - TSP-1 type 1 repeat
  • 82895 - TSP-1 type 1 repeat
  • 0Direct
    52743,52025
  • 52743 - Subtilisin-like
  • 52025 - PA domain
  • 0Direct
    49854,50494
  • 49854 - Spermadhesin, CUB domain
  • 50494 - Trypsin-like serine proteases
  • 0Direct
    53092,55920
  • 53092 - Creatinase/prolidase N-terminal domain
  • 55920 - Creatinase/aminopeptidase
  • 0Direct
    49464,53187
  • 49464 - Carboxypeptidase regulatory domain-like
  • 53187 - Zn-dependent exopeptidases
  • 0Direct
    100895,56487
  • 100895 - Kazal-type serine protease inhibitors
  • 56487 - SRCR-like
  • 0Direct
    50494,56672
  • 50494 - Trypsin-like serine proteases
  • 56672 - DNA/RNA polymerases
  • 0Direct
    57414,57440
  • 57414 - Hairpin loop containing domain-like
  • 57440 - Kringle-like
  • 0Direct
    47090,55486
  • 47090 - PGBD-like
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 0Direct
    143791,54236
  • 143791 - DUSP-like
  • 54236 - Ubiquitin-like
  • 0Direct
    101821,53187
  • 101821 - Aminopeptidase/glucanase lid domain
  • 53187 - Zn-dependent exopeptidases
  • 0Direct
    89260,89260
  • 89260 - Collagen-binding domain
  • 89260 - Collagen-binding domain
  • 0Direct
    53098,46919
  • 53098 - Ribonuclease H-like
  • 46919 - N-terminal Zn binding domain of HIV integrase
  • 0Direct
    57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0Direct
    56983,81296
  • 56983 - Viral glycoprotein, central and dimerisation domains
  • 81296 - E set domains
  • 0Direct
    47986,47986
  • 47986 - DEATH domain
  • 47986 - DEATH domain
  • 0Direct
    57756,50630
  • 57756 - Retrovirus zinc finger-like domains
  • 50630 - Acid proteases
  • 0Direct
    57850,54001
  • 57850 - RING/U-box
  • 54001 - Cysteine proteinases
  • 0Direct
    57603,57440
  • 57603 - FnI-like domain
  • 57440 - Kringle-like
  • 0Direct
    53098,50122
  • 53098 - Ribonuclease H-like
  • 50122 - DNA-binding domain of retroviral integrase
  • 0Direct
    74924,54001
  • 74924 - Cap-Gly domain
  • 54001 - Cysteine proteinases
  • 0Direct
    56601,50886
  • 56601 - beta-lactamase/transpeptidase-like
  • 50886 - D-aminopeptidase, middle and C-terminal domains
  • 0Direct
    140367,143076
  • 140367 - Coronavirus NSP7-like
  • 143076 - Coronavirus NSP8-like
  • 0Direct
    50630,56672
  • 50630 - Acid proteases
  • 56672 - DNA/RNA polymerases
  • 0Direct
    54897,53187
  • 54897 - Protease propeptides/inhibitors
  • 53187 - Zn-dependent exopeptidases
  • 0Direct
    53335,142877
  • 53335 - S-adenosyl-L-methionine-dependent methyltransferases
  • 142877 - EndoU-like
  • 0Direct
    54001,49758
  • 54001 - Cysteine proteinases
  • 49758 - Calpain large subunit, middle domain (domain III)
  • 0Direct
    57196,49854
  • 57196 - EGF/Laminin
  • 49854 - Spermadhesin, CUB domain
  • 0Direct
    54001,144232
  • 54001 - Cysteine proteinases
  • 144232 - HIT/MYND zinc finger-like
  • 0Direct
    52949,53187
  • 52949 - Macro domain-like
  • 53187 - Zn-dependent exopeptidases
  • 0Direct
    52540,54211
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 54211 - Ribosomal protein S5 domain 2-like
  • 0Direct
    52540,89043
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 89043 - Soluble domain of poliovirus core protein 3a
  • 0Direct
    49854,49854
  • 49854 - Spermadhesin, CUB domain
  • 49854 - Spermadhesin, CUB domain
  • 0Direct
    57630,57196
  • 57630 - GLA-domain
  • 57196 - EGF/Laminin
  • 0Direct
    101816,144246
  • 101816 - Replicase NSP9
  • 144246 - Coronavirus NSP10-like
  • 0Direct
    63737,55486
  • 63737 - Leukotriene A4 hydrolase N-terminal domain
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 0Direct
    143791,143791
  • 143791 - DUSP-like
  • 143791 - DUSP-like
  • 0Direct
    53335,56672
  • 53335 - S-adenosyl-L-methionine-dependent methyltransferases
  • 56672 - DNA/RNA polymerases
  • 0Direct
    52743,49785
  • 52743 - Subtilisin-like
  • 49785 - Galactose-binding domain-like
  • 0Direct
    58091,49899
  • 58091 - Clostridium neurotoxins, "coiled-coil" domain
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0Direct
    82671,49854
  • 82671 - SEA domain
  • 49854 - Spermadhesin, CUB domain
  • 0Direct
    53187,47672
  • 53187 - Zn-dependent exopeptidases
  • 47672 - Transferrin receptor-like dimerisation domain
  • 0Direct
    55486,51120
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 51120 - beta-Roll
  • 0Direct
    47836,47943
  • 47836 - Retroviral matrix proteins
  • 47943 - Retrovirus capsid protein, N-terminal core domain
  • 0Direct
    81761,53474
  • 81761 - X-Prolyl dipeptidyl aminopeptidase PepX, N-terminal domain
  • 53474 - alpha/beta-Hydrolases
  • 0Direct
    57440,50494
  • 57440 - Kringle-like
  • 50494 - Trypsin-like serine proteases
  • 0Direct
    57535,57535
  • 57535 - Complement control module/SCR domain
  • 57535 - Complement control module/SCR domain
  • 0Direct
    103642,55920
  • 103642 - Sec-C motif
  • 55920 - Creatinase/aminopeptidase
  • 0Direct
    143076,101816
  • 143076 - Coronavirus NSP8-like
  • 101816 - Replicase NSP9
  • 0Direct
    50886,50886
  • 50886 - D-aminopeptidase, middle and C-terminal domains
  • 50886 - D-aminopeptidase, middle and C-terminal domains
  • 0Direct
    47986,52129
  • 47986 - DEATH domain
  • 52129 - Caspase-like
  • 0Direct
    82171,53474
  • 82171 - DPP6 N-terminal domain-like
  • 53474 - alpha/beta-Hydrolases
  • 0Direct
    49299,89260
  • 49299 - PKD domain
  • 89260 - Collagen-binding domain
  • 0Direct
    52129,81296
  • 52129 - Caspase-like
  • 81296 - E set domains
  • 0Direct
    46919,53098
  • 46919 - N-terminal Zn binding domain of HIV integrase
  • 53098 - Ribonuclease H-like
  • 0Direct
    57424,50494
  • 57424 - LDL receptor-like module
  • 50494 - Trypsin-like serine proteases
  • 0Direct
    57424,56487
  • 57424 - LDL receptor-like module
  • 56487 - SRCR-like
  • 0Direct
    56487,57424
  • 56487 - SRCR-like
  • 57424 - LDL receptor-like module
  • 0Direct
    49899,49854
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49854 - Spermadhesin, CUB domain
  • 0Direct
    56601,69189
  • 56601 - beta-lactamase/transpeptidase-like
  • 69189 - Penicillin-binding protein associated domain
  • 0Direct
    56487,50494
  • 56487 - SRCR-like
  • 50494 - Trypsin-like serine proteases
  • 0Direct
    57535,53300
  • 57535 - Complement control module/SCR domain
  • 53300 - vWA-like
  • 0Direct
    57630,57440
  • 57630 - GLA-domain
  • 57440 - Kringle-like
  • 0Direct
    159936,52949
  • 159936 - NSP3A-like
  • 52949 - Macro domain-like
  • 0Direct
    49758,47473
  • 49758 - Calpain large subunit, middle domain (domain III)
  • 47473 - EF-hand
  • 0Direct
    48371,54001
  • 48371 - ARM repeat
  • 54001 - Cysteine proteinases
  • 0Direct
    49854,49899
  • 49854 - Spermadhesin, CUB domain
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0Direct
    57196,50494
  • 57196 - EGF/Laminin
  • 50494 - Trypsin-like serine proteases
  • 0Direct
    55920,46785
  • 55920 - Creatinase/aminopeptidase
  • 46785 - "Winged helix" DNA-binding domain
  • 0Direct
    57424,57424
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 0Direct
    57535,50494
  • 57535 - Complement control module/SCR domain
  • 50494 - Trypsin-like serine proteases
  • 0Direct
    53092,53092
  • 53092 - Creatinase/prolidase N-terminal domain
  • 53092 - Creatinase/prolidase N-terminal domain
  • 0Direct
    56672,53098
  • 56672 - DNA/RNA polymerases
  • 53098 - Ribonuclease H-like
  • 1.777e-16Direct
    50156,50156
  • 50156 - PDZ domain-like
  • 50156 - PDZ domain-like
  • 3.541e-16Direct
    56672,88633
  • 56672 - DNA/RNA polymerases
  • 88633 - Positive stranded ssRNA viruses
  • 0.000000008799Direct
    90209,90209
  • 90209 - Ran binding protein zinc finger-like
  • 90209 - Ran binding protein zinc finger-like
  • 0.000001658Direct
    53187,55031
  • 53187 - Zn-dependent exopeptidases
  • 55031 - Bacterial exopeptidase dimerisation domain
  • 0.000002102Direct
    52540,142877
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 142877 - EndoU-like
  • 0.0001232Direct
    49785,57184
  • 49785 - Galactose-binding domain-like
  • 57184 - Growth factor receptor domain
  • 0.0006136Direct
    56672,52540
  • 56672 - DNA/RNA polymerases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.0105Inherited
    52540,52540
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.375Inherited
    55486,48371
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 48371 - ARM repeat
  • 0.6749Inherited
    52540,56672
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 56672 - DNA/RNA polymerases
  • 1Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    89043,50494,56672
  • 89043 - Soluble domain of poliovirus core protein 3a
  • 50494 - Trypsin-like serine proteases
  • 56672 - DNA/RNA polymerases
  • 0Direct
    57424,57424,57424
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 0Direct
    53098,46919,53098
  • 53098 - Ribonuclease H-like
  • 46919 - N-terminal Zn binding domain of HIV integrase
  • 53098 - Ribonuclease H-like
  • 0Direct
    50494,50156,50156
  • 50494 - Trypsin-like serine proteases
  • 50156 - PDZ domain-like
  • 50156 - PDZ domain-like
  • 0Direct
    49854,57535,57535
  • 49854 - Spermadhesin, CUB domain
  • 57535 - Complement control module/SCR domain
  • 57535 - Complement control module/SCR domain
  • 0Direct
    57535,57535,53300
  • 57535 - Complement control module/SCR domain
  • 57535 - Complement control module/SCR domain
  • 53300 - vWA-like
  • 0Direct
    54001,143791,143791
  • 54001 - Cysteine proteinases
  • 143791 - DUSP-like
  • 143791 - DUSP-like
  • 0Direct
    82671,49854,49854
  • 82671 - SEA domain
  • 49854 - Spermadhesin, CUB domain
  • 49854 - Spermadhesin, CUB domain
  • 0Direct
    56487,57424,57424
  • 56487 - SRCR-like
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 0Direct
    50494,52540,89043
  • 50494 - Trypsin-like serine proteases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 89043 - Soluble domain of poliovirus core protein 3a
  • 0Direct
    55486,49899,49599
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49599 - TRAF domain-like
  • 0Direct
    50494,52540,56672
  • 50494 - Trypsin-like serine proteases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 56672 - DNA/RNA polymerases
  • 0Direct
    57414,57440,57440
  • 57414 - Hairpin loop containing domain-like
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 0Direct
    47090,55486,57440
  • 47090 - PGBD-like
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 57440 - Kringle-like
  • 0Direct
    53187,49464,53187
  • 53187 - Zn-dependent exopeptidases
  • 49464 - Carboxypeptidase regulatory domain-like
  • 53187 - Zn-dependent exopeptidases
  • 0Direct
    47986,47986,52129
  • 47986 - DEATH domain
  • 47986 - DEATH domain
  • 52129 - Caspase-like
  • 0Direct
    56672,53098,46919
  • 56672 - DNA/RNA polymerases
  • 53098 - Ribonuclease H-like
  • 46919 - N-terminal Zn binding domain of HIV integrase
  • 0Direct
    57630,57196,50494
  • 57630 - GLA-domain
  • 57196 - EGF/Laminin
  • 50494 - Trypsin-like serine proteases
  • 0Direct
    50630,56672,53098
  • 50630 - Acid proteases
  • 56672 - DNA/RNA polymerases
  • 53098 - Ribonuclease H-like
  • 0Direct
    55486,58091,49899
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 58091 - Clostridium neurotoxins, "coiled-coil" domain
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0Direct
    81761,53474,49785
  • 81761 - X-Prolyl dipeptidyl aminopeptidase PepX, N-terminal domain
  • 53474 - alpha/beta-Hydrolases
  • 49785 - Galactose-binding domain-like
  • 0Direct
    47090,55486,50923
  • 47090 - PGBD-like
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 50923 - Hemopexin-like domain
  • 0Direct
    88633,88633,88633
  • 88633 - Positive stranded ssRNA viruses
  • 88633 - Positive stranded ssRNA viruses
  • 88633 - Positive stranded ssRNA viruses
  • 0Direct
    58091,49899,50386
  • 58091 - Clostridium neurotoxins, "coiled-coil" domain
  • 49899 - Concanavalin A-like lectins/glucanases
  • 50386 - STI-like
  • 0Direct
    82895,82895,82895
  • 82895 - TSP-1 type 1 repeat
  • 82895 - TSP-1 type 1 repeat
  • 82895 - TSP-1 type 1 repeat
  • 0Direct
    57630,57196,57196
  • 57630 - GLA-domain
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0Direct
    57196,57196,50494
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 50494 - Trypsin-like serine proteases
  • 0Direct
    82671,57424,49854
  • 82671 - SEA domain
  • 57424 - LDL receptor-like module
  • 49854 - Spermadhesin, CUB domain
  • 0Direct
    100895,56487,57424
  • 100895 - Kazal-type serine protease inhibitors
  • 56487 - SRCR-like
  • 57424 - LDL receptor-like module
  • 0Direct
    54001,49758,47473
  • 54001 - Cysteine proteinases
  • 49758 - Calpain large subunit, middle domain (domain III)
  • 47473 - EF-hand
  • 0Direct
    49854,57424,56487
  • 49854 - Spermadhesin, CUB domain
  • 57424 - LDL receptor-like module
  • 56487 - SRCR-like
  • 0Direct
    49854,57196,49854
  • 49854 - Spermadhesin, CUB domain
  • 57196 - EGF/Laminin
  • 49854 - Spermadhesin, CUB domain
  • 0Direct
    57424,56487,50494
  • 57424 - LDL receptor-like module
  • 56487 - SRCR-like
  • 50494 - Trypsin-like serine proteases
  • 0Direct
    49854,49899,49854
  • 49854 - Spermadhesin, CUB domain
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49854 - Spermadhesin, CUB domain
  • 0Direct
    57440,57440,50494
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 50494 - Trypsin-like serine proteases
  • 0Direct
    57630,57184,50494
  • 57630 - GLA-domain
  • 57184 - Growth factor receptor domain
  • 50494 - Trypsin-like serine proteases
  • 0Direct
    57603,57440,57440
  • 57603 - FnI-like domain
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 0Direct
    52540,89043,50494
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 89043 - Soluble domain of poliovirus core protein 3a
  • 50494 - Trypsin-like serine proteases
  • 0Direct
    50494,56672,88633
  • 50494 - Trypsin-like serine proteases
  • 56672 - DNA/RNA polymerases
  • 88633 - Positive stranded ssRNA viruses
  • 0Direct
    143076,101816,144246
  • 143076 - Coronavirus NSP8-like
  • 101816 - Replicase NSP9
  • 144246 - Coronavirus NSP10-like
  • 0Direct
    54897,52743,49785
  • 54897 - Protease propeptides/inhibitors
  • 52743 - Subtilisin-like
  • 49785 - Galactose-binding domain-like
  • 0Direct
    50494,52540,52540
  • 50494 - Trypsin-like serine proteases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    49854,49854,50494
  • 49854 - Spermadhesin, CUB domain
  • 49854 - Spermadhesin, CUB domain
  • 50494 - Trypsin-like serine proteases
  • 0Direct
    52025,53187,47672
  • 52025 - PA domain
  • 53187 - Zn-dependent exopeptidases
  • 47672 - Transferrin receptor-like dimerisation domain
  • 0Direct
    49854,57424,57424
  • 49854 - Spermadhesin, CUB domain
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 0Direct
    55486,57440,57440
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 0Direct
    57424,49854,49899
  • 57424 - LDL receptor-like module
  • 49854 - Spermadhesin, CUB domain
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0Direct
    56601,50886,50886
  • 56601 - beta-lactamase/transpeptidase-like
  • 50886 - D-aminopeptidase, middle and C-terminal domains
  • 50886 - D-aminopeptidase, middle and C-terminal domains
  • 0Direct
    57535,57535,57535
  • 57535 - Complement control module/SCR domain
  • 57535 - Complement control module/SCR domain
  • 57535 - Complement control module/SCR domain
  • 0Direct
    47836,47943,47353
  • 47836 - Retroviral matrix proteins
  • 47943 - Retrovirus capsid protein, N-terminal core domain
  • 47353 - Retrovirus capsid dimerization domain-like
  • 0Direct
    49854,49854,57424
  • 49854 - Spermadhesin, CUB domain
  • 49854 - Spermadhesin, CUB domain
  • 57424 - LDL receptor-like module
  • 0Direct
    140367,143076,101816
  • 140367 - Coronavirus NSP7-like
  • 143076 - Coronavirus NSP8-like
  • 101816 - Replicase NSP9
  • 0Direct
    47353,57756,50630
  • 47353 - Retrovirus capsid dimerization domain-like
  • 57756 - Retrovirus zinc finger-like domains
  • 50630 - Acid proteases
  • 0Direct
    57630,57440,57440
  • 57630 - GLA-domain
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 0Direct
    57756,50630,56672
  • 57756 - Retrovirus zinc finger-like domains
  • 50630 - Acid proteases
  • 56672 - DNA/RNA polymerases
  • 0Direct
    46919,53098,50122
  • 46919 - N-terminal Zn binding domain of HIV integrase
  • 53098 - Ribonuclease H-like
  • 50122 - DNA-binding domain of retroviral integrase
  • 0Direct
    57535,53300,50494
  • 57535 - Complement control module/SCR domain
  • 53300 - vWA-like
  • 50494 - Trypsin-like serine proteases
  • 0Direct
    57440,57440,57440
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 0Direct
    63411,63411,63411
  • 63411 - LuxS/MPP-like metallohydrolase
  • 63411 - LuxS/MPP-like metallohydrolase
  • 63411 - LuxS/MPP-like metallohydrolase
  • 0Direct
    57535,57535,50494
  • 57535 - Complement control module/SCR domain
  • 57535 - Complement control module/SCR domain
  • 50494 - Trypsin-like serine proteases
  • 0Direct
    49464,53187,49464
  • 49464 - Carboxypeptidase regulatory domain-like
  • 53187 - Zn-dependent exopeptidases
  • 49464 - Carboxypeptidase regulatory domain-like
  • 0Direct
    47943,47353,57756
  • 47943 - Retrovirus capsid protein, N-terminal core domain
  • 47353 - Retrovirus capsid dimerization domain-like
  • 57756 - Retrovirus zinc finger-like domains
  • 0Direct
    57196,49854,57535
  • 57196 - EGF/Laminin
  • 49854 - Spermadhesin, CUB domain
  • 57535 - Complement control module/SCR domain
  • 0Direct
    49899,49854,57424
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49854 - Spermadhesin, CUB domain
  • 57424 - LDL receptor-like module
  • 0Direct
    54001,88633,88633
  • 54001 - Cysteine proteinases
  • 88633 - Positive stranded ssRNA viruses
  • 88633 - Positive stranded ssRNA viruses
  • 0Direct
    88633,50494,52540
  • 88633 - Positive stranded ssRNA viruses
  • 50494 - Trypsin-like serine proteases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    57424,57424,50494
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 50494 - Trypsin-like serine proteases
  • 0Direct
    52743,49785,57184
  • 52743 - Subtilisin-like
  • 49785 - Galactose-binding domain-like
  • 57184 - Growth factor receptor domain
  • 0Direct
    53092,53092,55920
  • 53092 - Creatinase/prolidase N-terminal domain
  • 53092 - Creatinase/prolidase N-terminal domain
  • 55920 - Creatinase/aminopeptidase
  • 0Direct
    52540,52540,142877
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 142877 - EndoU-like
  • 0.0009659Direct
    56672,52540,52540
  • 56672 - DNA/RNA polymerases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.004099Inherited
    63737,55486,48371
  • 63737 - Leukotriene A4 hydrolase N-terminal domain
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 48371 - ARM repeat
  • 0.6749Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
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