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Enzyme Commission (EC): DNA helicase

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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Root: EC Hierarchy (from IntEnz release 70)

Shortest distance to current term (+ for parents, - for children) EC term [EC ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + 4:   root [root] <7>
+ + + 3:   Hydrolases [3] <13>(406|681) (406|427|219)
+ + 2:   Acting on acid anhydrides [3.6] <5>(109|138) (109|111|78)
+ 1:   Acting on ATP; involved in cellular and subcellular movement [3.6.4] <13>(58|71) (58|57|33)
0:   DNA helicase [3.6.4.12](30|40) (30|30|16)


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
SPOC domain-like0Direct
RuvA domain 2-like0Direct
Origin of replication-binding domain, RBD-like0Direct
HRDC-like0Direct
Nucleic acid-binding proteins0Direct
AN1-like Zinc finger0Direct
vWA-like0Direct
Rap30/74 interaction domains0Direct
C-terminal domain of Ku800Direct
Coronavirus NSP7-like0Direct
DNA helicase RuvA subunit, C-terminal domain0Direct
Replicase NSP90Direct
Coronavirus NSP8-like0Direct
N-terminal domain of DnaB helicase0Direct
Hedgehog/intein (Hint) domain0Direct
DNA primase core0Direct
Prokaryotic type I DNA topoisomerase0Direct
"Winged helix" DNA-binding domain0Direct
BRK domain-like0Direct
Chromo domain-like0Direct
EndoU-like0Direct
Coronavirus NSP10-like0Direct
Restriction endonuclease-like0Direct
NSP3A-like0Direct
SAP domain5.003e-16Direct
Homing endonucleases0.0000000000001266Direct
FYVE/PHD zinc finger0.000000001343Direct
SARS Nsp1-like0.00000002606Direct
F-box domain0.0000001893Direct
Sec63 N-terminal domain-like0.0003238Direct


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Family

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SCOP termFDR (all)Annotation (direct or inherited)
Viral cysteine protease of trypsin fold0Direct
Replicase NSP90Direct
Extended AAA-ATPase domain0Direct
DNA helicase RuvA subunit, N-terminal domain0Direct
DNA-binding domain from rap300Direct
RecG "wedge" domain0Direct
Coronavirus NSP7-like0Direct
Ku70 subunit middle domain0Direct
TIP49 domain0Direct
Ku70 subunit N-terminal domain0Direct
Replication initiation protein E10Direct
DNA helicase RuvA subunit, C-terminal domain0Direct
HRDC domain from helicases0Direct
NSP3A-like0Direct
N-terminal domain of DnaB helicase0Direct
AN1-like Zinc finger0Direct
Helicase-like "domain" of reverse gyrase0Direct
Ku80 subunit middle domain0Direct
Helicase DNA-binding domain0Direct
Rap30/74 interaction domains0Direct
Coronavirus NSP8-like0Direct
Nsp15 C-terminal domain-like0Direct
DNA replication initiator (cdc21/cdc54) N-terminal domain0Direct
Achaeal helicase C-terminal domain0Direct
BRK domain-like0Direct
Exodeoxyribonuclease V beta chain (RecB), C-terminal domain0Direct
Nsp15 N-terminal domain-like0Direct
Prokaryotic type I DNA topoisomerase0Direct
Ku80 subunit N-terminal domain0Direct
Chromo domain0Direct
C-terminal domain of Ku800Direct
NTF2-like0Direct
Coronavirus NSP10-like0Direct
DNA helicase RuvA subunit, middle domain0Direct
SAP domain3.66e-16Direct
Intein (protein splicing domain)0.00000000003825Direct
SARS Nsp1-like0.00000001774Direct
F-box domain0.0000001338Direct
PHD domain0.000001641Direct
RecQ helicase DNA-binding domain-like0.000006055Direct


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Coronavirus NSP10-like0Direct
Coronavirus NSP8-like0Direct
AN1-like Zinc finger0Direct
Origin of replication-binding domain, RBD-like0Direct
Nucleic acid-binding proteins0Direct
Restriction endonuclease-like0Direct
DNA primase core0Direct
Prokaryotic type I DNA topoisomerase0Direct
vWA-like0Direct
Hedgehog/intein (Hint) domain0Direct
N-terminal domain of DnaB helicase0Direct
DNA helicase RuvA subunit, C-terminal domain0Direct
SPOC domain-like0Direct
NSP3A-like0Direct
Coronavirus NSP7-like0Direct
Chromo domain-like0Direct
BRK domain-like0Direct
Rap30/74 interaction domains0Direct
RuvA domain 2-like0Direct
HRDC-like0Direct
C-terminal domain of Ku800Direct
EndoU-like0Direct
Replicase NSP90Direct
"Winged helix" DNA-binding domain0Direct
SAP domain3.506e-16Direct
Homing endonucleases0.00000000000009032Direct
FYVE/PHD zinc finger0.000000001005Direct
SARS Nsp1-like0.00000001987Direct
F-box domain0.000000146Direct
Sec63 N-terminal domain-like0.0002651Direct

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
52540,56712
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 56712 - Prokaryotic type I DNA topoisomerase
  • 0Direct
    50249,52540
  • 50249 - Nucleic acid-binding proteins
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    55464,52540
  • 55464 - Origin of replication-binding domain, RBD-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    50249,47781
  • 50249 - Nucleic acid-binding proteins
  • 47781 - RuvA domain 2-like
  • 0Direct
    52540,47819
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 47819 - HRDC-like
  • 0Direct
    140367,143076
  • 140367 - Coronavirus NSP7-like
  • 143076 - Coronavirus NSP8-like
  • 0Direct
    143076,101816
  • 143076 - Coronavirus NSP8-like
  • 101816 - Replicase NSP9
  • 0Direct
    53300,100939
  • 53300 - vWA-like
  • 100939 - SPOC domain-like
  • 0Direct
    55608,56712
  • 55608 - Homing endonucleases
  • 56712 - Prokaryotic type I DNA topoisomerase
  • 0Direct
    56672,52540
  • 56672 - DNA/RNA polymerases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    52540,142877
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 142877 - EndoU-like
  • 0Direct
    160481,160481
  • 160481 - BRK domain-like
  • 160481 - BRK domain-like
  • 0Direct
    54160,54160
  • 54160 - Chromo domain-like
  • 54160 - Chromo domain-like
  • 0Direct
    50916,46785
  • 50916 - Rap30/74 interaction domains
  • 46785 - "Winged helix" DNA-binding domain
  • 0Direct
    100939,101420
  • 100939 - SPOC domain-like
  • 101420 - C-terminal domain of Ku80
  • 0Direct
    54160,52540
  • 54160 - Chromo domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    52540,46785
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 46785 - "Winged helix" DNA-binding domain
  • 0Direct
    101816,144246
  • 101816 - Replicase NSP9
  • 144246 - Coronavirus NSP10-like
  • 0Direct
    47781,46929
  • 47781 - RuvA domain 2-like
  • 46929 - DNA helicase RuvA subunit, C-terminal domain
  • 0Direct
    56731,52540
  • 56731 - DNA primase core
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    53335,142877
  • 53335 - S-adenosyl-L-methionine-dependent methyltransferases
  • 142877 - EndoU-like
  • 0Direct
    48024,52540
  • 48024 - N-terminal domain of DnaB helicase
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    100939,68906
  • 100939 - SPOC domain-like
  • 68906 - SAP domain
  • 0Direct
    52540,51294
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 51294 - Hedgehog/intein (Hint) domain
  • 0Direct
    46785,47819
  • 46785 - "Winged helix" DNA-binding domain
  • 47819 - HRDC-like
  • 0Direct
    51294,55608
  • 51294 - Hedgehog/intein (Hint) domain
  • 55608 - Homing endonucleases
  • 0.000000000001292Direct
    159936,52949
  • 159936 - NSP3A-like
  • 52949 - Macro domain-like
  • 0.00000001987Direct
    56712,51294
  • 56712 - Prokaryotic type I DNA topoisomerase
  • 51294 - Hedgehog/intein (Hint) domain
  • 0.00000002997Direct
    159936,53335
  • 159936 - NSP3A-like
  • 53335 - S-adenosyl-L-methionine-dependent methyltransferases
  • 0.0000004291Direct
    55608,52540
  • 55608 - Homing endonucleases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.000001934Direct

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    54160,54160,52540
  • 54160 - Chromo domain-like
  • 54160 - Chromo domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    52540,56712,51294
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 56712 - Prokaryotic type I DNA topoisomerase
  • 51294 - Hedgehog/intein (Hint) domain
  • 0Direct
    48024,52540,51294
  • 48024 - N-terminal domain of DnaB helicase
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 51294 - Hedgehog/intein (Hint) domain
  • 0Direct
    56672,52540,52540
  • 56672 - DNA/RNA polymerases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    53300,100939,68906
  • 53300 - vWA-like
  • 100939 - SPOC domain-like
  • 68906 - SAP domain
  • 0Direct
    140367,143076,101816
  • 140367 - Coronavirus NSP7-like
  • 143076 - Coronavirus NSP8-like
  • 101816 - Replicase NSP9
  • 0Direct
    52540,52540,56712
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 56712 - Prokaryotic type I DNA topoisomerase
  • 0Direct
    53300,100939,101420
  • 53300 - vWA-like
  • 100939 - SPOC domain-like
  • 101420 - C-terminal domain of Ku80
  • 0Direct
    50249,52540,52540
  • 50249 - Nucleic acid-binding proteins
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    52540,52540,47819
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 47819 - HRDC-like
  • 0Direct
    143076,101816,144246
  • 143076 - Coronavirus NSP8-like
  • 101816 - Replicase NSP9
  • 144246 - Coronavirus NSP10-like
  • 0Direct
    54160,52540,52540
  • 54160 - Chromo domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    50249,47781,46929
  • 50249 - Nucleic acid-binding proteins
  • 47781 - RuvA domain 2-like
  • 46929 - DNA helicase RuvA subunit, C-terminal domain
  • 0Direct
    52540,46785,47819
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 46785 - "Winged helix" DNA-binding domain
  • 47819 - HRDC-like
  • 0Direct
    52540,52540,142877
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 142877 - EndoU-like
  • 0Direct
    52540,51294,55608
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 51294 - Hedgehog/intein (Hint) domain
  • 55608 - Homing endonucleases
  • 0.00000000001822Direct


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
    (show help)