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Enzyme Commission (EC): Racemases and epimerases

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Root: EC Hierarchy (from IntEnz release 70)

Shortest distance to current term (+ for parents, - for children) EC term [EC ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + 2:   root [root] <7>
+ 1:   Isomerases [5] <7>(128|160) (128|76|32)
0:   Racemases and epimerases [5.1] <4>(32|33) (32|15|8)
- 1:   Acting on carbohydrates and derivatives [5.1.3] <46>(15|14) (15|3|2)
- 1:   Acting on amino acids and derivatives [5.1.1] <25>(10|11) (10|8|4)
- 1:   Acting on other compounds [5.1.99] <8>(5|5) (5|1|0)
- 1:   Acting on hydroxy acids and derivatives [5.1.2] <7>(3|3) (3|3|2)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
Aspartate/glutamate racemase0Direct
ClpP/crotonase0Direct
Diaminopimelate epimerase-like0Direct
PLP-binding barrel0Direct
YjeF N-terminal domain-like0Direct
AraD/HMP-PK domain-like0Direct
NAD(P)-binding Rossmann-fold domains0Direct
Dimeric alpha+beta barrel0Direct
Kelch motif0Direct
6-phosphogluconate dehydrogenase C-terminal domain-like0Direct
Alanine racemase C-terminal domain-like0Direct
Galactose mutarotase-like5.111e-16Direct
beta-Roll0.0000000001399Direct
Ribokinase-like0.000000005427Direct
ACP-like0.000002253Direct
Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase0.00001939Direct
Six-hairpin glycosidases0.00008629Direct
CoA-transferase family III (CaiB/BaiF)0.0004619Direct
Chondroitin AC/alginate lyase0.001052Inherited
Pectin lyase-like0.001388Inherited
CoA-dependent acyltransferases0.003381Inherited
Acetyl-CoA synthetase-like0.1726Inherited
Tetrahydrobiopterin biosynthesis enzymes-like0.24Inherited
Tryptophan synthase beta subunit-like PLP-dependent enzymes0.4236Inherited
Enolase N-terminal domain-like0.6035Inherited
Enolase C-terminal domain-like0.6638Inherited
Xylose isomerase-like0.8961Inherited
UDP-Glycosyltransferase/glycogen phosphorylase0.9038Inherited
RbsD-like1Inherited
SIS domain1Inherited
Ribulose-phoshate binding barrel1Inherited
RmlC-like cupins1Inherited


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Family

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SCOP termFDR (all)Annotation (direct or inherited)
Alanine racemase-like, N-terminal domain0Direct
YiiL-like0Direct
Kelch motif0Direct
Tyrosine-dependent oxidoreductases0Direct
Methylmalonyl-CoA epimerase0Direct
Alanine racemase0Direct
YjeF N-terminal domain-like0Direct
AraD-like aldolase/epimerase0Direct
Hypothetical protein HI13170Direct
D-ribulose-5-phosphate 3-epimerase0Direct
Crotonase-like0Direct
Diaminopimelate epimerase0Direct
Aspartate/glutamate racemase0Direct
UDP-N-acetylglucosamine 2-epimerase0Direct
NanE-like0Direct
Proline racemase0Direct
6-phosphogluconate dehydrogenase-like, N-terminal domain0Direct
HCDH C-domain-like0Direct
Aldose 1-epimerase (mutarotase)0Direct
YjeF C-terminal domain-like0Direct
Peptidyl carrier domain0.000000000004538Direct
DHN aldolase/epimerase0.00000000001116Direct
dTDP-sugar isomerase0.00000000008712Direct
Serralysin-like metalloprotease, C-terminal domain0.0000000001558Direct
NRPS condensation domain (amide synthase)0.00000003018Direct
N-acylglucosamine (NAG) epimerase0.00000003142Direct
CoA-transferase family III (CaiB/BaiF)0.0004777Direct
D-glucarate dehydratase-like0.001915Inherited
double-SIS domain0.1405Inherited
Acetyl-CoA synthetase-like0.1806Inherited
Tryptophan synthase beta subunit-like PLP-dependent enzymes0.438Inherited
Enolase N-terminal domain-like0.748Inherited
RbsD-like1Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Dimeric alpha+beta barrel0Direct
PLP-binding barrel0Direct
NAD(P)-binding Rossmann-fold domains0Direct
YjeF N-terminal domain-like0Direct
6-phosphogluconate dehydrogenase C-terminal domain-like0Direct
Diaminopimelate epimerase-like0Direct
ClpP/crotonase0Direct
AraD/HMP-PK domain-like0Direct
Alanine racemase C-terminal domain-like0Direct
Kelch motif0Direct
Aspartate/glutamate racemase0Direct
Galactose mutarotase-like3.548e-16Direct
beta-Roll0.000000000103Direct
Ribokinase-like0.00000000408Direct
ACP-like0.000001767Direct
Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase0.00001544Direct
Six-hairpin glycosidases0.00006947Direct
CoA-transferase family III (CaiB/BaiF)0.0003774Direct
Chondroitin AC/alginate lyase0.0008677Direct
Pectin lyase-like0.001149Inherited
CoA-dependent acyltransferases0.002825Inherited
Acetyl-CoA synthetase-like0.1523Inherited
Tetrahydrobiopterin biosynthesis enzymes-like0.2139Inherited
Tryptophan synthase beta subunit-like PLP-dependent enzymes0.3846Inherited
Enolase N-terminal domain-like0.5539Inherited
Enolase C-terminal domain-like0.6097Inherited
Xylose isomerase-like0.827Inherited
UDP-Glycosyltransferase/glycogen phosphorylase0.8343Inherited
RbsD-like0.9717Inherited
RmlC-like cupins1Inherited
SIS domain1Inherited
Ribulose-phoshate binding barrel1Inherited

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
54506,54506
  • 54506 - Diaminopimelate epimerase-like
  • 54506 - Diaminopimelate epimerase-like
  • 0Direct
    53681,53681
  • 53681 - Aspartate/glutamate racemase
  • 53681 - Aspartate/glutamate racemase
  • 0Direct
    51419,50621
  • 51419 - PLP-binding barrel
  • 50621 - Alanine racemase C-terminal domain-like
  • 0Direct
    51735,48179
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like
  • 0Direct
    51126,51120
  • 51126 - Pectin lyase-like
  • 51120 - beta-Roll
  • 0Direct
    52096,51735
  • 52096 - ClpP/crotonase
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 0Direct
    48179,48179
  • 48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like
  • 48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like
  • 0Direct
    51735,74650
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 74650 - Galactose mutarotase-like
  • 0Direct
    64153,53613
  • 64153 - YjeF N-terminal domain-like
  • 53613 - Ribokinase-like
  • 0Direct
    51120,51120
  • 51120 - beta-Roll
  • 51120 - beta-Roll
  • 0.0000000000001893Direct
    56801,47336
  • 56801 - Acetyl-CoA synthetase-like
  • 47336 - ACP-like
  • 0.000000000002974Direct
    47336,52777
  • 47336 - ACP-like
  • 52777 - CoA-dependent acyltransferases
  • 0.000000000005537Direct
    52777,56801
  • 52777 - CoA-dependent acyltransferases
  • 56801 - Acetyl-CoA synthetase-like
  • 0.0000005052Direct
    52777,52777
  • 52777 - CoA-dependent acyltransferases
  • 52777 - CoA-dependent acyltransferases
  • 0.0000009236Direct
    54826,51604
  • 54826 - Enolase N-terminal domain-like
  • 51604 - Enolase C-terminal domain-like
  • 0.5421Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    51735,48179,48179
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like
  • 48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like
  • 0Direct
    52096,51735,48179
  • 52096 - ClpP/crotonase
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like
  • 0Direct
    51126,51120,51120
  • 51126 - Pectin lyase-like
  • 51120 - beta-Roll
  • 51120 - beta-Roll
  • 0Direct
    56801,47336,52777
  • 56801 - Acetyl-CoA synthetase-like
  • 47336 - ACP-like
  • 52777 - CoA-dependent acyltransferases
  • 0.0000000000001216Direct
    51120,51120,51120
  • 51120 - beta-Roll
  • 51120 - beta-Roll
  • 51120 - beta-Roll
  • 0.0000000000001893Direct
    47336,52777,52777
  • 47336 - ACP-like
  • 52777 - CoA-dependent acyltransferases
  • 52777 - CoA-dependent acyltransferases
  • 0.000000000005537Direct
    52777,52777,56801
  • 52777 - CoA-dependent acyltransferases
  • 52777 - CoA-dependent acyltransferases
  • 56801 - Acetyl-CoA synthetase-like
  • 0.00000002311Direct
    52777,56801,47336
  • 52777 - CoA-dependent acyltransferases
  • 56801 - Acetyl-CoA synthetase-like
  • 47336 - ACP-like
  • 0.0000000455Direct


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
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