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Fly Phenotype (FP): phenotype

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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Root: FP Hierarchy (fly phenotype from FlyBase controlled vocabulary with sub-ontology "phenotypic class")

Shortest distance to current term (+ for parents, - for children) FP term [FP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ 1:   phenotypic class [FBcv:0000347] <4>
0:   phenotype [FBcv:0001347] <62>(175|208) (176|81|29)
- 1:   behavior defective [FBcv:0000387] <13>(12|11) (12|4|0)
- 1:   stress response defective [FBcv:0000408] <8>(1|4) (1|2|0)
- 1:   sensory perception defective [FBcv:0000681] <5>(4|4) (5|4|1)
- 1:   size defective [FBcv:0000357] <5>(4|7) (4|4|3)
- 1:   embryonic/larval segmentation phenotype [FBcv:0000698] <4>(1|2) (1|0|0)
- 1:   cell cycle defective [FBcv:0000671] <3>(5|7) (6|2|0)
- 1:   temperature response defective [FBcv:0000683] <3>(1|2) (1|0|0)
- 1:   visible [FBcv:0000354] <3>(8|14) (10|2|3)
- 1:   aging defective [FBcv:0000384] <2>(0|0) (0|0|0)
- 1:   cell death defective [FBcv:0000424] <2>(3|5) (3|1|0)
- 1:   cell growth defective [FBcv:0000427] <2>(1|1) (1|0|0)
- 1:   cell number defective [FBcv:0000709] <2>(7|11) (7|5|1)
- 1:   cell size defective [FBcv:0000428] <2>(2|4) (3|1|0)
- 1:   increased mortality [FBcv:0002004] <2>(55|72) (55|19|7)
- 1:   jumping defective [FBcv:0000415] <2>(0|0) (0|0|0)
- 1:   mating defective [FBcv:0000400] <2>(2|4) (2|0|0)
- 1:   modifier of variegation [FBcv:0000008] <2>(6|5) (6|1|0)
- 1:   semi-fertile [FBcv:0000375] <2>(0|0) (0|0|0)
- 1:   semi-sterile [FBcv:0000365] <2>(1|2) (1|1|0)
- 1:   sterile [FBcv:0000364] <2>(4|4) (5|6|1)
- 1:   axis specification defective [FBcv:0000686] <1>(0|0) (0|0|0)
- 1:   circadian rhythm defective [FBcv:0000394] <1>(3|4) (6|1|0)
- 1:   developmental rate defective [FBcv:0000450] <1>(3|1) (2|0|0)
- 1:   diapause defective [FBcv:0000706] <1>(0|0) (0|0|0)
- 1:   eclosion defective [FBcv:0000670] <1>(1|1) (1|0|0)
- 1:   flight defective [FBcv:0000417] <1>(1|1) (1|0|0)
- 1:   paralytic [FBcv:0000389] <1>(0|1) (0|0|0)
- 1:   auxotroph [FBcv:0000383](1|1) (1|0|0)
- 1:   cell adhesion defective [FBcv:0000668](1|1) (1|3|2)
- 1:   cell lethal [FBcv:0000353](2|1) (1|0|0)
- 1:   cell migration defective [FBcv:0000716](3|3) (3|3|2)
- 1:   cell polarity defective [FBcv:0000430](6|6) (6|3|3)
- 1:   cell shape defective [FBcv:0000429](1|1) (1|0|0)
- 1:   chemical resistant [FBcv:0000439](3|3) (3|1|0)
- 1:   chemical sensitive [FBcv:0000440](2|1) (2|0|0)
- 1:   decreased fecundity [FBcv:0006002](1|2) (1|0|0)
- 1:   decreased occurrence of cell division [FBcv:0006006](3|4) (3|1|0)
- 1:   electrophoretic variant [FBcv:0000438](2|2) (2|0|0)
- 1:   endocytosis defective [FBcv:0001324](0|0) (0|0|0)
- 1:   exocytosis defective [FBcv:0001325](0|0) (0|0|0)
- 1:   grandchildless [FBcv:0000378](0|0) (0|0|0)
- 1:   gravitaxis defective [FBcv:0000388](0|0) (0|0|0)
- 1:   homeotic [FBcv:0000316](2|4) (2|0|0)
- 1:   hyperactive [FBcv:0000392](1|1) (1|0|0)
- 1:   hypoactive [FBcv:0000390](3|3) (3|1|1)
- 1:   immune response defective [FBcv:0000448](2|5) (2|2|0)
- 1:   increased fecundity [FBcv:0006001](0|0) (0|0|0)
- 1:   increased occurrence of cell division [FBcv:0006005](1|2) (1|1|0)
- 1:   long lived [FBcv:0000386](1|1) (1|0|0)
- 1:   melanotic mass phenotype [FBcv:0000446](1|0) (1|0|0)
- 1:   melanotic necrosis [FBcv:0000447](0|0) (0|0|0)
- 1:   neuroanatomy defective [FBcv:0000435](9|11) (9|2|5)
- 1:   neurogenic phenotype [FBcv:0000325](0|0) (0|0|0)
- 1:   neurophysiology defective [FBcv:0000434](6|8) (7|0|0)
- 1:   non-enhancer of variegation [FBcv:0000380](0|0) (0|0|0)
- 1:   non-suppressor of variegation [FBcv:0000382](2|0) (2|0|0)
- 1:   phototaxis defective [FBcv:0000413](2|2) (2|1|0)
- 1:   planar polarity defective [FBcv:0000449](4|5) (4|1|1)
- 1:   radiation resistant [FBcv:0000441](0|0) (0|0|0)
- 1:   radiation sensitive [FBcv:0000442](1|1) (1|1|0)
- 1:   sex-determination defective [FBcv:0000436](0|0) (0|0|0)
- 1:   sleep defective [FBcv:0000705](2|2) (2|0|0)


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Superfamily

(show details)
SCOP termFDR (all)Annotation (direct or inherited)
Aquaporin-like0Direct
Sema domain0Direct
Orange domain-like0Direct
L30e-like0Direct
GINS helical bundle-like0Direct
Periplasmic binding protein-like I0Direct
Conserved domain common to transcription factors TFIIS, elongin A, CRSP700Direct
ARID-like0Direct
Integrin domains0Direct
Glutamine synthetase/guanido kinase0Direct
CBS-domain pair0Direct
Putative DNA-binding domain0Direct
Roadblock/LC7 domain0Direct
Ferritin-like0Direct
Zn-binding ribosomal proteins0Direct
TIMP-like0Direct
Heat shock protein 70kD (HSP70), C-terminal subdomain0Direct
Tetrahydrobiopterin biosynthesis enzymes-like0Direct
RNase III domain-like0Direct
Ribosomal L27 protein-like0Direct
Cysteine-rich DNA binding domain, (DM domain)0Direct
DEATH domain0Direct
GroEL-intermediate domain like0Direct
GroEL equatorial domain-like0Direct
E2F-DP heterodimerization region0Direct
ThrRS/AlaRS common domain0Direct
lambda repressor-like DNA-binding domains0Direct
Ribosomal protein L10Direct
Nucleoporin domain0Direct
Translation proteins SH3-like domain0Direct
HLH, helix-loop-helix DNA-binding domain0Direct
Caspase-like0Direct
PYP-like sensor domain (PAS domain)0Direct
Mob1/phocein0Direct
PriA/YqbF domain0Direct
Class I glutamine amidotransferase-like0Direct
Retrovirus zinc finger-like domains0Direct
Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit0Direct
Hormone receptor domain0Direct
Heat shock protein 70kD (HSP70), peptide-binding domain0Direct
Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain0Direct
L27 domain0Direct
ValRS/IleRS/LeuRS editing domain0Direct
Formin homology 2 domain (FH2 domain)0Direct
Sec7 domain0Direct
CAD & PB1 domains0Direct
TATA-box binding protein-like0Direct
C-terminal, gelsolin-like domain of Sec23/240Direct
Multidrug efflux transporter AcrB transmembrane domain0Direct
Seven-hairpin glycosidases0Direct
Skp1 dimerisation domain-like0Direct
HR1 repeat0Direct
Smc hinge domain0Direct
SPOC domain-like0Direct
DEK C-terminal domain0Direct
Transducin (alpha subunit), insertion domain0Direct
Prefoldin0Direct
KA1-like0Direct
Restriction endonuclease-like0Direct
A DNA-binding domain in eukaryotic transcription factors0Direct
Plexin repeat0Direct
Cytokine0Direct
Snake toxin-like0Direct
Bromodomain0Direct
Toll/Interleukin receptor TIR domain0Direct
Lipocalins0Direct
YVTN repeat-like/Quinoprotein amine dehydrogenase0Direct
S15/NS1 RNA-binding domain0Direct
Zinc beta-ribbon0Direct
Sec1/munc18-like (SM) proteins0Direct
Succinyl-CoA synthetase domains0Direct
PIN domain-like0Direct
Blood coagulation inhibitor (disintegrin)0Direct
beta and beta-prime subunits of DNA dependent RNA-polymerase0Direct
Bet v1-like0Direct
SAP domain0Direct
Clathrin adaptor appendage domain0Direct
SMAD/FHA domain0Direct
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor0Direct
Aminoacid dehydrogenase-like, N-terminal domain0Direct
N-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
Riboflavin synthase domain-like0Direct
vWA-like0Direct
ACT-like0Direct
HSP90 C-terminal domain0Direct
HRDC-like0Direct
Ribosomal protein S5 domain 2-like0Direct
Regulator of G-protein signaling, RGS0Direct
Activating enzymes of the ubiquitin-like proteins0Direct
PX domain0Direct
Terpenoid synthases0Direct
Translational machinery components0Direct
SAND domain-like0Direct
PapD-like0Direct
Rudiment single hybrid motif0Direct
Ferredoxin reductase-like, C-terminal NADP-linked domain0Direct
C-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
Tropomyosin0Direct
4Fe-4S ferredoxins0Direct
B-box zinc-binding domain0Direct
Isocitrate/Isopropylmalate dehydrogenase-like0Direct
Nop domain0Direct
ACP-like0Direct
2Fe-2S ferredoxin-like0Direct
Aromatic aminoacid monoxygenases, catalytic and oligomerization domains0Direct
RBP11-like subunits of RNA polymerase0Direct
DNA-binding domain0Direct
SMAD MH1 domain0Direct
Aldolase0Direct
Subtilisin-like0Direct
PreATP-grasp domain0Direct
Insulin-like0Direct
Spectrin repeat0Direct
Sm-like ribonucleoproteins0Direct
Taf5 N-terminal domain-like0Direct
Pectin lyase-like0Direct
GroEL apical domain-like0Direct
Ribonuclease PH domain 2-like0Direct
SAICAR synthase-like0Direct
Nuclear receptor ligand-binding domain0Direct
SNARE-like0Direct
Cu,Zn superoxide dismutase-like0Direct
DNA/RNA polymerases0Direct
dsRNA-binding domain-like0Direct
JAB1/MPN domain0Direct
Class II aaRS ABD-related0Direct
Homeodomain-like0.000002727Direct
ARM repeat0.00002446Direct
SH3-domain0.00007519Direct
Protein kinase-like (PK-like)0.0001984Direct
EGF/Laminin0.01402Inherited
Nucleotidylyl transferase0.0687Inherited
beta-sandwich domain of Sec23/240.08083Inherited
Cysteine-rich domain0.08083Inherited
Leucine zipper domain0.09382Inherited
PDZ domain-like0.09497Inherited
Cyclin-like0.1077Inherited
Periplasmic binding protein-like II0.1135Inherited
EF-hand0.1194Inherited
BRCT domain0.1261Inherited
FYVE/PHD zinc finger0.1272Inherited
Fibronectin type III0.1486Inherited
SNARE fusion complex0.1486Inherited
beta-beta-alpha zinc fingers0.1577Inherited
Concanavalin A-like lectins/glucanases0.2061Inherited
C2 domain (Calcium/lipid-binding domain, CaLB)0.2169Inherited
Tudor/PWWP/MBT0.2247Inherited
N-acetylmuramoyl-L-alanine amidase-like0.2353Inherited
Cysteine proteinases0.2483Inherited
Chromo domain-like0.2799Inherited
Ankyrin repeat0.2802Inherited
Macro domain-like0.3656Inherited
SCOP hierarchy in SUPERFAMILY0.3946Inherited
SH2 domain0.3958Inherited
P-loop containing nucleoside triphosphate hydrolases0.4022Inherited
Voltage-gated potassium channels0.4264Inherited
Growth factor receptor domain0.4264Inherited
POZ domain0.4636Inherited
SAM/Pointed domain0.4657Inherited
Cystine-knot cytokines0.4769Inherited
PAZ domain0.4908Inherited
RNA-binding domain, RBD0.5299Inherited
Tubulin nucleotide-binding domain-like0.5391Inherited
Ribonuclease H-like0.5719Inherited
Glucocorticoid receptor-like (DNA-binding domain)0.5828Inherited
cAMP-binding domain-like0.6079Inherited
Cadherin-like0.6079Inherited
Family A G protein-coupled receptor-like0.6326Inherited
Neurotransmitter-gated ion-channel transmembrane pore0.6518Inherited
Nicotinic receptor ligand binding domain-like0.6518Inherited
SET domain0.7326Inherited
Immunoglobulin0.7885Inherited
Nucleotide cyclase0.8452Inherited
NAD(P)-binding Rossmann-fold domains0.9439Inherited
alpha/beta-Hydrolases1Inherited


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

(show details)
SCOP termFDR (all)Annotation (direct or inherited)
Single strand DNA-binding domain, SSB0Direct
Hypoxia-inducible factor Hif2a, C-terminal domain0Direct
TBP-associated factors, TAFs0Direct
Myb/SANT domain0Direct
DEK C-terminal domain0Direct
Ngr ectodomain-like0Direct
beta-CASP RNA-metabolising hydrolases0Direct
Isoprenyl diphosphate synthases0Direct
Subtilases0Direct
HLH, helix-loop-helix DNA-binding domain0Direct
Extracellular domain of cell surface receptors0Direct
MIF4G domain-like0Direct
Dimeric isocitrate & isopropylmalate dehydrogenases0Direct
Ferredoxin domains from multidomain proteins0Direct
Sm motif of small nuclear ribonucleoproteins, SNRNP0Direct
Astacin0Direct
Leucine aminopeptidase (Aminopeptidase A), N-terminal domain0Direct
2Fe-2S ferredoxin domains from multidomain proteins0Direct
Erythroid transcription factor GATA-10Direct
Class I alpha-1;2-mannosidase, catalytic domain0Direct
Forkhead DNA-binding domain0Direct
Aromatic aminoacid monoxygenases, catalytic and oligomerization domains0Direct
Penta-EF-hand proteins0Direct
Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain0Direct
CAD domain0Direct
ZZ domain0Direct
Armadillo repeat0Direct
Ribonuclease PH domain 1-like0Direct
FHA domain0Direct
Transforming growth factor (TGF)-beta0Direct
Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit0Direct
GroEL-like chaperone, intermediate domain0Direct
H-NOX domain0Direct
Transcriptional factor domain0Direct
L-arabinose binding protein-like0Direct
Aquaporin-like0Direct
Histidine acid phosphatase0Direct
Protein serine/threonine phosphatase0Direct
C-terminal, gelsolin-like domain of Sec23/240Direct
MBT repeat0Direct
Fibroblast growth factors (FGF)0Direct
Histone lysine methyltransferases0Direct
T-box0Direct
Nuclear receptor0Direct
ValRS/IleRS/LeuRS editing domain0Direct
Group II chaperonin (CCT, TRIC), intermediate domain0Direct
L30e/L7ae ribosomal proteins0Direct
BC C-terminal domain-like0Direct
Anticodon-binding domain of Class II aaRS0Direct
Paired domain0Direct
La domain0Direct
ARID domain0Direct
Clathrin coat assembly domain0Direct
Laminin-type module0Direct
Neurolysin-like0Direct
SMAD MH1 domain0Direct
Bromodomain0Direct
Clathrin adaptor core protein0Direct
S-adenosylhomocystein hydrolase0Direct
Acyl-carrier protein (ACP)0Direct
Calmodulin-like0Direct
Phoshoinositide 3-kinase (PI3K) helical domain0Direct
Tropomyosin0Direct
Phosphatidylinositol phosphate kinase IIbeta, PIPK IIbeta0Direct
BAR domain0Direct
B-box zinc-binding domain0Direct
N-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
Nop domain0Direct
Nuclear receptor ligand-binding domain0Direct
Hsp90 middle domain0Direct
GMC oxidoreductases0Direct
SAP domain0Direct
Sema domain0Direct
RUNT domain0Direct
Ubiquitin carboxyl-terminal hydrolase, UCH0Direct
MSP-like0Direct
Aminoacid dehydrogenase-like, C-terminal domain0Direct
Cell cycle transcription factor e2f-dp0Direct
IF2B-like0Direct
Laminin G-like module0Direct
Dachshund-homology domain0Direct
Regulator of G-protein signaling, RGS0Direct
Sec1/munc18-like (SM) proteins0Direct
Sec7 domain0Direct
Group II chaperonin (CCT, TRIC), ATPase domain0Direct
Transducin (alpha subunit), insertion domain0Direct
Gelsolin-like0Direct
Rhomboid-like0Direct
Succinyl-CoA synthetase domains0Direct
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor0Direct
RecA protein-like (ATPase-domain)0Direct
Leucine aminopeptidase, C-terminal domain0Direct
Smc hinge domain0Direct
Hormone receptor domain0Direct
Ribosomal protein L10Direct
Cell cycle control phosphatase, catalytic domain0Direct
Diap1 N-terninal region-like0Direct
Plexin repeat0Direct
Spectrin repeat0Direct
Ribonuclease PH domain 2-like0Direct
Blood coagulation inhibitor (disintegrin)0Direct
Cu,Zn superoxide dismutase-like0Direct
Meta-cation ATPase, catalytic domain P0Direct
Insulin-like0Direct
Cyclin0Direct
PLC-like (P variant)0Direct
BC N-terminal domain-like0Direct
GroEL-like chaperone, apical domain0Direct
Heat shock protein 70kD (HSP70), peptide-binding domain0Direct
NF-kappa-B/REL/DORSAL transcription factors, C-terminal domain0Direct
BC ATP-binding domain-like0Direct
L27 domain0Direct
SMAD domain0Direct
ets domain0Direct
RNase III catalytic domain-like0Direct
Hairy Orange domain0Direct
Toll/Interleukin receptor TIR domain0Direct
a tRNA synthase domain0Direct
Calpain large subunit, catalytic domain (domain II)0Direct
Translational machinery components0Direct
NHL repeat0Direct
Discoidin domain (FA58C, coagulation factor 5/8 C-terminal domain)0Direct
Ubiquitin activating enzymes (UBA)0Direct
Alcohol dehydrogenase-like, N-terminal domain0Direct
Zf-UBP0Direct
Conserved domain common to transcription factors TFIIS, elongin A, CRSP700Direct
Succinyl-CoA synthetase, beta-chain, N-terminal domain0Direct
PAPS sulfotransferase0Direct
Heat shock protein 70kD (HSP70), C-terminal subdomain0Direct
Cysteine-rich DNA binding domain, (DM domain)0Direct
Class I glutamine amidotransferases (GAT)0Direct
Multidrug efflux transporter AcrB transmembrane domain0Direct
Nitrogenase iron protein-like0Direct
Ubiquitin carboxyl-terminal hydrolase UCH-L0Direct
Group II chaperonin (CCT, TRIC), apical domain0Direct
Prefoldin0Direct
Reprolysin-like0Direct
Heat shock protein 90, HSP90, N-terminal domain0Direct
First domain of FERM0Direct
POU-specific domain0Direct
DEATH domain, DD0Direct
Pointed domain0Direct
Integrin domains0Direct
Phoshoinositide 3-kinase (PI3K), catalytic domain0Direct
Skp1 dimerisation domain-like0Direct
C-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
XPF/Rad1/Mus81 nuclease0Direct
Taf5 N-terminal domain-like0Direct
CBS-domain pair0Direct
HR1 repeat0Direct
Chromo barrel domain0Direct
Mob1/phocein0Direct
MAM domain0Direct
Retrovirus zinc finger-like domains0Direct
Enabled/VASP homology 1 domain (EVH1 domain)0Direct
A DNA-binding domain in eukaryotic transcription factors0Direct
Inositol polyphosphate kinase (IPK)0Direct
Caspase catalytic domain0Direct
GroEL chaperone, ATPase domain0Direct
PX domain0Direct
Double-stranded RNA-binding domain (dsRBD)0Direct
Alcohol dehydrogenase-like, C-terminal domain0Direct
Roadblock/LC7 domain0Direct
Rel/Dorsal transcription factors, DNA-binding domain0Direct
Arrestin/Vps26-like0Direct
Formin homology 2 domain (FH2 domain)0Direct
Eps15 homology domain (EH domain)0Direct
TATA-box binding protein (TBP), C-terminal domain0Direct
Protein kinases, catalytic subunit0.000007202Direct
Homeodomain0.00002279Direct
SH3-domain0.0001667Direct
Pleckstrin-homology domain (PH domain)0.009906Inherited
PDZ domain0.01908Inherited
Motor proteins0.03119Inherited
I set domains0.05729Inherited
EGF-type module0.07803Inherited
Tandem AAA-ATPase domain0.09482Inherited
Phosphate binding protein-like0.1036Inherited
Leucine zipper domain0.1036Inherited
Class I aminoacyl-tRNA synthetases (RS), catalytic domain0.1595Inherited
SAM (sterile alpha motif) domain0.185Inherited
Fibronectin type III0.2021Inherited
PHD domain0.2329Inherited
N-acetylmuramoyl-L-alanine amidase-like0.2418Inherited
Dual specificity phosphatase-like0.2418Inherited
Classic zinc finger, C2H20.3236Inherited
Ankyrin repeat0.3672Inherited
Tetramerization domain of potassium channels0.3672Inherited
Extended AAA-ATPase domain0.3824Inherited
Glutathione peroxidase-like0.4248Inherited
Pancreatic lipase, N-terminal domain0.4248Inherited
SH2 domain0.4418Inherited
Rhodopsin-like0.4524Inherited
Growth factor receptor domain0.4574Inherited
Canonical RBD0.4844Inherited
UBA domain0.4898Inherited
Synaptotagmin-like (S variant)0.5063Inherited
Tubulin, GTPase domain0.5619Inherited
PAZ domain0.5688Inherited
Voltage-gated potassium channels0.6585Inherited
Neurotransmitter-gated ion-channel transmembrane pore0.6829Inherited
cAMP-binding domain0.6829Inherited
Cadherin0.6829Inherited
G proteins0.7288Inherited
Acetylcholinesterase-like0.765Inherited
Nicotinic receptor ligand binding domain-like0.7689Inherited
Adenylyl and guanylyl cyclase catalytic domain0.8661Inherited
Neutral endopeptidase (neprilysin)0.9652Inherited


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Supra-domain (including individual superfamily)

(show details)
Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Heat shock protein 70kD (HSP70), peptide-binding domain0Direct
DNA-binding domain0Direct
Ribosomal L27 protein-like0Direct
Plexin repeat0Direct
DNA/RNA polymerases0Direct
HLH, helix-loop-helix DNA-binding domain0Direct
Seven-hairpin glycosidases0Direct
KA1-like0Direct
Tetrahydrobiopterin biosynthesis enzymes-like0Direct
Sm-like ribonucleoproteins0Direct
TATA-box binding protein-like0Direct
Ribonuclease PH domain 2-like0Direct
Zn-binding ribosomal proteins0Direct
Class I glutamine amidotransferase-like0Direct
HR1 repeat0Direct
SMAD/FHA domain0Direct
SAP domain0Direct
4Fe-4S ferredoxins0Direct
2Fe-2S ferredoxin-like0Direct
SMAD MH1 domain0Direct
Class II aaRS ABD-related0Direct
SPOC domain-like0Direct
Nuclear receptor ligand-binding domain0Direct
N-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
Aromatic aminoacid monoxygenases, catalytic and oligomerization domains0Direct
PYP-like sensor domain (PAS domain)0Direct
PriA/YqbF domain0Direct
Ribosomal protein L10Direct
vWA-like0Direct
ACT-like0Direct
Skp1 dimerisation domain-like0Direct
GINS helical bundle-like0Direct
GroEL-intermediate domain like0Direct
Restriction endonuclease-like0Direct
C-terminal, gelsolin-like domain of Sec23/240Direct
Caspase-like0Direct
Cytokine0Direct
DEATH domain0Direct
Orange domain-like0Direct
Cysteine-rich DNA binding domain, (DM domain)0Direct
Ferredoxin reductase-like, C-terminal NADP-linked domain0Direct
Glutamine synthetase/guanido kinase0Direct
ThrRS/AlaRS common domain0Direct
Terpenoid synthases0Direct
Formin homology 2 domain (FH2 domain)0Direct
Aldolase0Direct
RBP11-like subunits of RNA polymerase0Direct
Ferritin-like0Direct
Subtilisin-like0Direct
Regulator of G-protein signaling, RGS0Direct
Activating enzymes of the ubiquitin-like proteins0Direct
Roadblock/LC7 domain0Direct
Toll/Interleukin receptor TIR domain0Direct
C-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
Retrovirus zinc finger-like domains0Direct
Heat shock protein 70kD (HSP70), C-terminal subdomain0Direct
Integrin domains0Direct
GroEL apical domain-like0Direct
Snake toxin-like0Direct
HRDC-like0Direct
DEK C-terminal domain0Direct
Nucleoporin domain0Direct
Aquaporin-like0Direct
Cu,Zn superoxide dismutase-like0Direct
TIMP-like0Direct
S15/NS1 RNA-binding domain0Direct
GroEL equatorial domain-like0Direct
ValRS/IleRS/LeuRS editing domain0Direct
ARID-like0Direct
Aminoacid dehydrogenase-like, N-terminal domain0Direct
Blood coagulation inhibitor (disintegrin)0Direct
B-box zinc-binding domain0Direct
Hormone receptor domain0Direct
JAB1/MPN domain0Direct
Lipocalins0Direct
beta and beta-prime subunits of DNA dependent RNA-polymerase0Direct
Clathrin adaptor appendage domain0Direct
L30e-like0Direct
Sec7 domain0Direct
A DNA-binding domain in eukaryotic transcription factors0Direct
E2F-DP heterodimerization region0Direct
Transducin (alpha subunit), insertion domain0Direct
CBS-domain pair0Direct
Tropomyosin0Direct
SNARE-like0Direct
Nop domain0Direct
PX domain0Direct
lambda repressor-like DNA-binding domains0Direct
Translational machinery components0Direct
Multidrug efflux transporter AcrB transmembrane domain0Direct
Ribosomal protein S5 domain 2-like0Direct
Succinyl-CoA synthetase domains0Direct
Rudiment single hybrid motif0Direct
Taf5 N-terminal domain-like0Direct
Smc hinge domain0Direct
SAICAR synthase-like0Direct
YVTN repeat-like/Quinoprotein amine dehydrogenase0Direct
Sema domain0Direct
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor0Direct
PapD-like0Direct
Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit0Direct
Mob1/phocein0Direct
Conserved domain common to transcription factors TFIIS, elongin A, CRSP700Direct
Isocitrate/Isopropylmalate dehydrogenase-like0Direct
CAD & PB1 domains0Direct
Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain0Direct
HSP90 C-terminal domain0Direct
Spectrin repeat0Direct
Putative DNA-binding domain0Direct
Bromodomain0Direct
SAND domain-like0Direct
Sec1/munc18-like (SM) proteins0Direct
L27 domain0Direct
RNase III domain-like0Direct
ACP-like0Direct
Riboflavin synthase domain-like0Direct
Translation proteins SH3-like domain0Direct
Periplasmic binding protein-like I0Direct
dsRNA-binding domain-like0Direct
Prefoldin0Direct
PreATP-grasp domain0Direct
Insulin-like0Direct
Pectin lyase-like0Direct
Bet v1-like0Direct
Zinc beta-ribbon0Direct
PIN domain-like0Direct
Homeodomain-like0.000001983Direct
ARM repeat0.00001808Direct
SH3-domain0.00005622Direct
Protein kinase-like (PK-like)0.0001503Direct
EGF/Laminin0.01152Inherited
p53-like transcription factors0.05902Inherited
Nucleotidylyl transferase0.05902Inherited
beta-sandwich domain of Sec23/240.06971Inherited
Cysteine-rich domain0.06971Inherited
Leucine zipper domain0.08168Inherited
PDZ domain-like0.08283Inherited
Cyclin-like0.09426Inherited
Periplasmic binding protein-like II0.0993Inherited
EF-hand0.1043Inherited
BRCT domain0.1101Inherited
FYVE/PHD zinc finger0.111Inherited
Fibronectin type III0.1303Inherited
SNARE fusion complex0.1303Inherited
beta-beta-alpha zinc fingers0.1382Inherited
Concanavalin A-like lectins/glucanases0.1819Inherited
C2 domain (Calcium/lipid-binding domain, CaLB)0.1921Inherited
Tudor/PWWP/MBT0.1987Inherited
N-acetylmuramoyl-L-alanine amidase-like0.209Inherited
Cysteine proteinases0.2217Inherited
Chromo domain-like0.2523Inherited
Ankyrin repeat0.2527Inherited
HMG-box0.2711Inherited
Macro domain-like0.3346Inherited
SH2 domain0.3631Inherited
P-loop containing nucleoside triphosphate hydrolases0.3694Inherited
Voltage-gated potassium channels0.394Inherited
Growth factor receptor domain0.394Inherited
POZ domain0.4305Inherited
SAM/Pointed domain0.4326Inherited
Cystine-knot cytokines0.4432Inherited
PAZ domain0.4579Inherited
RNA-binding domain, RBD0.4973Inherited
Tubulin nucleotide-binding domain-like0.507Inherited
Ribonuclease H-like0.5408Inherited
Glucocorticoid receptor-like (DNA-binding domain)0.5523Inherited
Cadherin-like0.5769Inherited
cAMP-binding domain-like0.5769Inherited
Family A G protein-coupled receptor-like0.6027Inherited
Neurotransmitter-gated ion-channel transmembrane pore0.6232Inherited
Nicotinic receptor ligand binding domain-like0.6232Inherited
SET domain0.7077Inherited
Immunoglobulin0.7625Inherited
Nucleotide cyclase0.8238Inherited
NAD(P)-binding Rossmann-fold domains0.9289Inherited
alpha/beta-Hydrolases1Inherited

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
48425,50729
  • 48425 - Sec7 domain
  • 50729 - PH domain-like
  • 0Direct
    50615,52540
  • 50615 - N-terminal domain of alpha and beta subunits of F1 ATP synthase
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    49417,81296
  • 49417 - p53-like transcription factors
  • 81296 - E set domains
  • 0Direct
    54695,81382
  • 54695 - POZ domain
  • 81382 - Skp1 dimerisation domain-like
  • 0Direct
    50044,55550
  • 50044 - SH3-domain
  • 55550 - SH2 domain
  • 0Direct
    50677,52374
  • 50677 - ValRS/IleRS/LeuRS editing domain
  • 52374 - Nucleotidylyl transferase
  • 0Direct
    57850,57850
  • 57850 - RING/U-box
  • 57850 - RING/U-box
  • 0Direct
    54849,52029
  • 54849 - GroEL-intermediate domain like
  • 52029 - GroEL apical domain-like
  • 0Direct
    49562,48371
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 48371 - ARM repeat
  • 0Direct
    55550,56112
  • 55550 - SH2 domain
  • 56112 - Protein kinase-like (PK-like)
  • 0Direct
    54768,54768
  • 54768 - dsRNA-binding domain-like
  • 54768 - dsRNA-binding domain-like
  • 0Direct
    48592,54849
  • 48592 - GroEL equatorial domain-like
  • 54849 - GroEL-intermediate domain like
  • 0Direct
    50156,50044
  • 50156 - PDZ domain-like
  • 50044 - SH3-domain
  • 0Direct
    54236,47031
  • 54236 - Ubiquitin-like
  • 47031 - Second domain of FERM
  • 0Direct
    46785,144074
  • 46785 - "Winged helix" DNA-binding domain
  • 144074 - E2F-DP heterodimerization region
  • 0Direct
    46689,46689
  • 46689 - Homeodomain-like
  • 46689 - Homeodomain-like
  • 0Direct
    54211,55666
  • 54211 - Ribosomal protein S5 domain 2-like
  • 55666 - Ribonuclease PH domain 2-like
  • 0Direct
    53067,100920
  • 53067 - Actin-like ATPase domain
  • 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
  • 0Direct
    57196,49899
  • 57196 - EGF/Laminin
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0Direct
    52540,47917
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 47917 - C-terminal domain of alpha and beta subunits of F1 ATP synthase
  • 0Direct
    46966,46966
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 0Direct
    46785,46785
  • 46785 - "Winged helix" DNA-binding domain
  • 46785 - "Winged helix" DNA-binding domain
  • 0Direct
    101288,50156
  • 101288 - L27 domain
  • 50156 - PDZ domain-like
  • 0Direct
    55486,57552
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 57552 - Blood coagulation inhibitor (disintegrin)
  • 0Direct
    47413,46689
  • 47413 - lambda repressor-like DNA-binding domains
  • 46689 - Homeodomain-like
  • 0Direct
    57889,57889
  • 57889 - Cysteine-rich domain
  • 57889 - Cysteine-rich domain
  • 0Direct
    56059,51246
  • 56059 - Glutathione synthetase ATP-binding domain-like
  • 51246 - Rudiment single hybrid motif
  • 0Direct
    57716,46689
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 46689 - Homeodomain-like
  • 0Direct
    55945,55945
  • 55945 - TATA-box binding protein-like
  • 55945 - TATA-box binding protein-like
  • 0Direct
    55021,56534
  • 55021 - ACT-like
  • 56534 - Aromatic aminoacid monoxygenases, catalytic and oligomerization domains
  • 0Direct
    53223,51735
  • 53223 - Aminoacid dehydrogenase-like, N-terminal domain
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 0Direct
    46785,54928
  • 46785 - "Winged helix" DNA-binding domain
  • 54928 - RNA-binding domain, RBD
  • 0Direct
    57184,57196
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 0Direct
    100920,100934
  • 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
  • 100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain
  • 0Direct
    57184,57184
  • 57184 - Growth factor receptor domain
  • 57184 - Growth factor receptor domain
  • 0Direct
    54211,54980
  • 54211 - Ribosomal protein S5 domain 2-like
  • 54980 - EF-G C-terminal domain-like
  • 0Direct
    54791,54791
  • 54791 - Eukaryotic type KH-domain (KH-domain type I)
  • 54791 - Eukaryotic type KH-domain (KH-domain type I)
  • 0Direct
    49265,49265
  • 49265 - Fibronectin type III
  • 49265 - Fibronectin type III
  • 0Direct
    47954,47954
  • 47954 - Cyclin-like
  • 47954 - Cyclin-like
  • 0Direct
    63748,63748
  • 63748 - Tudor/PWWP/MBT
  • 63748 - Tudor/PWWP/MBT
  • 0Direct
    54980,54211
  • 54980 - EF-G C-terminal domain-like
  • 54211 - Ribosomal protein S5 domain 2-like
  • 0Direct
    56112,48371
  • 56112 - Protein kinase-like (PK-like)
  • 48371 - ARM repeat
  • 0Direct
    55681,52954
  • 55681 - Class II aaRS and biotin synthetases
  • 52954 - Class II aaRS ABD-related
  • 0Direct
    52440,56059
  • 52440 - PreATP-grasp domain
  • 56059 - Glutathione synthetase ATP-binding domain-like
  • 0Direct
    47459,158457
  • 47459 - HLH, helix-loop-helix DNA-binding domain
  • 158457 - Orange domain-like
  • 0Direct
    101912,103575
  • 101912 - Sema domain
  • 103575 - Plexin repeat
  • 0Direct
    52058,52058
  • 52058 - L domain-like
  • 52058 - L domain-like
  • 0Direct
    50044,52540
  • 50044 - SH3-domain
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    55753,55753
  • 55753 - Actin depolymerizing proteins
  • 55753 - Actin depolymerizing proteins
  • 0Direct
    57903,47370
  • 57903 - FYVE/PHD zinc finger
  • 47370 - Bromodomain
  • 0Direct
    57716,48508
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 48508 - Nuclear receptor ligand-binding domain
  • 0Direct
    111418,81321
  • 111418 - Hormone receptor domain
  • 81321 - Family A G protein-coupled receptor-like
  • 0Direct
    49265,48726
  • 49265 - Fibronectin type III
  • 48726 - Immunoglobulin
  • 0Direct
    52949,53187
  • 52949 - Macro domain-like
  • 53187 - Zn-dependent exopeptidases
  • 0Direct
    56059,52210
  • 56059 - Glutathione synthetase ATP-binding domain-like
  • 52210 - Succinyl-CoA synthetase domains
  • 0Direct
    48371,56112
  • 48371 - ARM repeat
  • 56112 - Protein kinase-like (PK-like)
  • 0Direct
    52058,48726
  • 52058 - L domain-like
  • 48726 - Immunoglobulin
  • 0Direct
    47459,55785
  • 47459 - HLH, helix-loop-helix DNA-binding domain
  • 55785 - PYP-like sensor domain (PAS domain)
  • 0Direct
    57903,57903
  • 57903 - FYVE/PHD zinc finger
  • 57903 - FYVE/PHD zinc finger
  • 0Direct
    49899,57196
  • 49899 - Concanavalin A-like lectins/glucanases
  • 57196 - EGF/Laminin
  • 0Direct
    57196,49854
  • 57196 - EGF/Laminin
  • 49854 - Spermadhesin, CUB domain
  • 0Direct
    50044,50044
  • 50044 - SH3-domain
  • 50044 - SH3-domain
  • 0Direct
    52374,47323
  • 52374 - Nucleotidylyl transferase
  • 47323 - Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
  • 0Direct
    55550,50044
  • 55550 - SH2 domain
  • 50044 - SH3-domain
  • 0Direct
    47895,52540
  • 47895 - Transducin (alpha subunit), insertion domain
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    52113,52113
  • 52113 - BRCT domain
  • 52113 - BRCT domain
  • 0Direct
    54534,48452
  • 54534 - FKBP-like
  • 48452 - TPR-like
  • 0Direct
    57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.1534Inherited
    50978,50978
  • 50978 - WD40 repeat-like
  • 50978 - WD40 repeat-like
  • 0.209Inherited
    48726,49265
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 0.2195Inherited
    51045,51045
  • 51045 - WW domain
  • 51045 - WW domain
  • 0.2464Inherited
    48726,48726
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 0.3213Inherited
    48403,48403
  • 48403 - Ankyrin repeat
  • 48403 - Ankyrin repeat
  • 0.3346Inherited
    49899,49899
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.362Inherited
    57196,57184
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 0.3916Inherited
    57667,57667
  • 57667 - beta-beta-alpha zinc fingers
  • 57667 - beta-beta-alpha zinc fingers
  • 0.4292Inherited
    101690,53098
  • 101690 - PAZ domain
  • 53098 - Ribonuclease H-like
  • 0.5377Inherited
    63712,90112
  • 63712 - Nicotinic receptor ligand binding domain-like
  • 90112 - Neurotransmitter-gated ion-channel transmembrane pore
  • 0.6232Inherited
    52540,52540
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.6509Inherited
    49313,49313
  • 49313 - Cadherin-like
  • 49313 - Cadherin-like
  • 0.6728Inherited
    57625,57625
  • 57625 - Invertebrate chitin-binding proteins
  • 57625 - Invertebrate chitin-binding proteins
  • 0.7495Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    57850,57850,57850
  • 57850 - RING/U-box
  • 57850 - RING/U-box
  • 57850 - RING/U-box
  • 0Direct
    50615,52540,47917
  • 50615 - N-terminal domain of alpha and beta subunits of F1 ATP synthase
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 47917 - C-terminal domain of alpha and beta subunits of F1 ATP synthase
  • 0Direct
    53067,53067,100920
  • 53067 - Actin-like ATPase domain
  • 53067 - Actin-like ATPase domain
  • 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
  • 0Direct
    55753,55753,55753
  • 55753 - Actin depolymerizing proteins
  • 55753 - Actin depolymerizing proteins
  • 55753 - Actin depolymerizing proteins
  • 0Direct
    46966,46966,46966
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 0Direct
    50156,50044,52540
  • 50156 - PDZ domain-like
  • 50044 - SH3-domain
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    52440,56059,51246
  • 52440 - PreATP-grasp domain
  • 56059 - Glutathione synthetase ATP-binding domain-like
  • 51246 - Rudiment single hybrid motif
  • 0Direct
    49265,48726,48726
  • 49265 - Fibronectin type III
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 0Direct
    54236,47031,50729
  • 54236 - Ubiquitin-like
  • 47031 - Second domain of FERM
  • 50729 - PH domain-like
  • 0Direct
    101288,50156,50044
  • 101288 - L27 domain
  • 50156 - PDZ domain-like
  • 50044 - SH3-domain
  • 0Direct
    48452,48452,48452
  • 48452 - TPR-like
  • 48452 - TPR-like
  • 48452 - TPR-like
  • 0Direct
    48592,54849,52029
  • 48592 - GroEL equatorial domain-like
  • 54849 - GroEL-intermediate domain like
  • 52029 - GroEL apical domain-like
  • 0Direct
    49899,57196,57196
  • 49899 - Concanavalin A-like lectins/glucanases
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0Direct
    53067,100920,100934
  • 53067 - Actin-like ATPase domain
  • 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
  • 100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain
  • 0Direct
    49899,49899,49899
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0Direct
    57184,57196,57196
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0Direct
    57196,49899,49899
  • 57196 - EGF/Laminin
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0Direct
    52058,52058,52058
  • 52058 - L domain-like
  • 52058 - L domain-like
  • 52058 - L domain-like
  • 0Direct
    57196,57184,57196
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 0Direct
    54980,54211,54980
  • 54980 - EF-G C-terminal domain-like
  • 54211 - Ribosomal protein S5 domain 2-like
  • 54980 - EF-G C-terminal domain-like
  • 0Direct
    81296,81296,81296
  • 81296 - E set domains
  • 81296 - E set domains
  • 81296 - E set domains
  • 0Direct
    49562,48371,56112
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 48371 - ARM repeat
  • 56112 - Protein kinase-like (PK-like)
  • 0Direct
    48726,48726,49265
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 0.04242Inherited
    57196,57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.1303Inherited
    48726,48726,48726
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 0.2203Inherited
    52540,52540,52540
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.2867Inherited
    57625,57625,57625
  • 57625 - Invertebrate chitin-binding proteins
  • 57625 - Invertebrate chitin-binding proteins
  • 57625 - Invertebrate chitin-binding proteins
  • 0.4579Inherited
    49313,49313,49313
  • 49313 - Cadherin-like
  • 49313 - Cadherin-like
  • 49313 - Cadherin-like
  • 0.7195Inherited
    57667,57667,57667
  • 57667 - beta-beta-alpha zinc fingers
  • 57667 - beta-beta-alpha zinc fingers
  • 57667 - beta-beta-alpha zinc fingers
  • 0.8525Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
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