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Fly Phenotype (FP): phenotype

(show info)

Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Root: FP Hierarchy (fly phenotype from FlyBase controlled vocabulary with sub-ontology "phenotypic class")

Shortest distance to current term (+ for parents, - for children) FP term [FP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ 1:   phenotypic class [FBcv:0000347] <4>
0:   phenotype [FBcv:0001347] <62>(174|206) (175|81|30)
- 1:   behavior defective [FBcv:0000387] <13>(13|11) (13|3|0)
- 1:   stress response defective [FBcv:0000408] <8>(1|4) (1|2|0)
- 1:   sensory perception defective [FBcv:0000681] <5>(5|5) (6|4|1)
- 1:   size defective [FBcv:0000357] <5>(4|7) (4|4|3)
- 1:   embryonic/larval segmentation phenotype [FBcv:0000698] <4>(1|2) (1|0|0)
- 1:   cell cycle defective [FBcv:0000671] <3>(5|7) (6|2|0)
- 1:   temperature response defective [FBcv:0000683] <3>(1|1) (1|0|0)
- 1:   visible [FBcv:0000354] <3>(12|14) (13|3|3)
- 1:   aging defective [FBcv:0000384] <2>(0|0) (0|0|0)
- 1:   cell death defective [FBcv:0000424] <2>(3|5) (3|1|0)
- 1:   cell growth defective [FBcv:0000427] <2>(1|1) (1|0|0)
- 1:   cell number defective [FBcv:0000709] <2>(6|11) (7|6|1)
- 1:   cell size defective [FBcv:0000428] <2>(2|4) (3|1|0)
- 1:   increased mortality [FBcv:0002004] <2>(55|71) (55|19|8)
- 1:   jumping defective [FBcv:0000415] <2>(0|0) (0|0|0)
- 1:   mating defective [FBcv:0000400] <2>(2|4) (2|0|0)
- 1:   modifier of variegation [FBcv:0000008] <2>(6|5) (6|1|0)
- 1:   semi-fertile [FBcv:0000375] <2>(0|0) (0|0|0)
- 1:   semi-sterile [FBcv:0000365] <2>(1|2) (1|1|0)
- 1:   sterile [FBcv:0000364] <2>(3|4) (5|6|1)
- 1:   axis specification defective [FBcv:0000686] <1>(0|0) (0|0|0)
- 1:   circadian rhythm defective [FBcv:0000394] <1>(6|5) (6|1|0)
- 1:   developmental rate defective [FBcv:0000450] <1>(3|1) (2|0|0)
- 1:   diapause defective [FBcv:0000706] <1>(0|0) (0|0|0)
- 1:   eclosion defective [FBcv:0000670] <1>(1|1) (1|0|0)
- 1:   flight defective [FBcv:0000417] <1>(1|1) (1|0|0)
- 1:   paralytic [FBcv:0000389] <1>(0|1) (0|0|0)
- 1:   auxotroph [FBcv:0000383](1|1) (1|0|0)
- 1:   cell adhesion defective [FBcv:0000668](1|1) (3|3|2)
- 1:   cell lethal [FBcv:0000353](2|1) (1|0|0)
- 1:   cell migration defective [FBcv:0000716](3|2) (3|3|3)
- 1:   cell polarity defective [FBcv:0000430](6|6) (6|3|3)
- 1:   cell shape defective [FBcv:0000429](1|1) (1|0|0)
- 1:   chemical resistant [FBcv:0000439](3|3) (3|1|0)
- 1:   chemical sensitive [FBcv:0000440](2|1) (2|0|0)
- 1:   decreased fecundity [FBcv:0006002](1|2) (1|0|0)
- 1:   decreased occurrence of cell division [FBcv:0006006](3|4) (3|1|0)
- 1:   electrophoretic variant [FBcv:0000438](2|2) (2|0|0)
- 1:   endocytosis defective [FBcv:0001324](0|0) (0|0|0)
- 1:   exocytosis defective [FBcv:0001325](0|0) (0|0|0)
- 1:   grandchildless [FBcv:0000378](0|0) (0|0|0)
- 1:   gravitaxis defective [FBcv:0000388](0|0) (0|0|0)
- 1:   homeotic [FBcv:0000316](2|4) (2|0|0)
- 1:   hyperactive [FBcv:0000392](1|1) (1|0|0)
- 1:   hypoactive [FBcv:0000390](3|3) (3|1|1)
- 1:   immune response defective [FBcv:0000448](2|5) (3|2|0)
- 1:   increased fecundity [FBcv:0006001](0|0) (0|0|0)
- 1:   increased occurrence of cell division [FBcv:0006005](1|2) (1|1|0)
- 1:   long lived [FBcv:0000386](1|1) (1|0|0)
- 1:   melanotic mass phenotype [FBcv:0000446](0|0) (0|0|0)
- 1:   melanotic necrosis [FBcv:0000447](0|0) (0|0|0)
- 1:   neuroanatomy defective [FBcv:0000435](9|11) (9|2|5)
- 1:   neurogenic phenotype [FBcv:0000325](0|0) (0|0|0)
- 1:   neurophysiology defective [FBcv:0000434](6|8) (7|0|0)
- 1:   non-enhancer of variegation [FBcv:0000380](0|0) (0|0|0)
- 1:   non-suppressor of variegation [FBcv:0000382](2|0) (2|0|0)
- 1:   phototaxis defective [FBcv:0000413](2|2) (2|1|0)
- 1:   planar polarity defective [FBcv:0000449](4|5) (4|1|1)
- 1:   radiation resistant [FBcv:0000441](0|0) (0|0|0)
- 1:   radiation sensitive [FBcv:0000442](1|1) (1|1|0)
- 1:   sex-determination defective [FBcv:0000436](0|0) (0|0|0)
- 1:   sleep defective [FBcv:0000705](2|2) (2|0|0)


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Superfamily

(show details)
SCOP termFDR (all)Annotation (direct or inherited)
Skp1 dimerisation domain-like0Direct
Transducin (alpha subunit), insertion domain0Direct
N-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
Riboflavin synthase domain-like0Direct
Bromodomain0Direct
RBP11-like subunits of RNA polymerase0Direct
KA1-like0Direct
Nuclear receptor ligand-binding domain0Direct
HR1 repeat0Direct
S15/NS1 RNA-binding domain0Direct
Glutamine synthetase/guanido kinase0Direct
GroEL equatorial domain-like0Direct
HSP90 C-terminal domain0Direct
Orange domain-like0Direct
PurM N-terminal domain-like0Direct
Formin homology 2 domain (FH2 domain)0Direct
Subtilisin-like0Direct
Sec7 domain0Direct
GroEL-intermediate domain like0Direct
Putative DNA-binding domain0Direct
Insulin-like0Direct
Lipocalins0Direct
Mob1/phocein0Direct
Heat shock protein 70kD (HSP70), C-terminal subdomain0Direct
Translational machinery components0Direct
SMAD MH1 domain0Direct
Taf5 N-terminal domain-like0Direct
SMAD/FHA domain0Direct
SAP domain0Direct
Ferredoxin reductase-like, C-terminal NADP-linked domain0Direct
Nop domain0Direct
GINS helical bundle-like0Direct
Rudiment single hybrid motif0Direct
B-box zinc-binding domain0Direct
Blood coagulation inhibitor (disintegrin)0Direct
Restriction endonuclease-like0Direct
ThrRS/AlaRS common domain0Direct
DNA/RNA polymerases0Direct
PIN domain-like0Direct
Roadblock/LC7 domain0Direct
C-terminal, gelsolin-like domain of Sec23/240Direct
Clathrin adaptor appendage domain0Direct
4Fe-4S ferredoxins0Direct
PreATP-grasp domain0Direct
beta and beta-prime subunits of DNA dependent RNA-polymerase0Direct
Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit0Direct
Aquaporin-like0Direct
TATA-box binding protein-like0Direct
PX domain0Direct
vWA-like0Direct
Aromatic aminoacid monoxygenases, catalytic and oligomerization domains0Direct
CBS-domain pair0Direct
Caspase-like0Direct
PurM C-terminal domain-like0Direct
E2F-DP heterodimerization region0Direct
Pectin lyase-like0Direct
HLH, helix-loop-helix DNA-binding domain0Direct
ARID-like0Direct
Cu,Zn superoxide dismutase-like0Direct
ACP-like0Direct
C-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
SNARE-like0Direct
GroEL apical domain-like0Direct
lambda repressor-like DNA-binding domains0Direct
Aldolase0Direct
Ribosomal protein L10Direct
SPOC domain-like0Direct
Smc hinge domain0Direct
Tetrahydrobiopterin biosynthesis enzymes-like0Direct
Sema domain0Direct
Regulator of G-protein signaling, RGS0Direct
Cytokine0Direct
Isocitrate/Isopropylmalate dehydrogenase-like0Direct
DNA-binding domain0Direct
Bet v1-like0Direct
YVTN repeat-like/Quinoprotein amine dehydrogenase0Direct
Spectrin repeat0Direct
Tropomyosin0Direct
Prefoldin0Direct
Integrin domains0Direct
Ferritin-like0Direct
Sm-like ribonucleoproteins0Direct
Toll/Interleukin receptor TIR domain0Direct
PriA/YqbF domain0Direct
Class I glutamine amidotransferase-like0Direct
Sec1/munc18-like (SM) proteins0Direct
CAD & PB1 domains0Direct
Activating enzymes of the ubiquitin-like proteins0Direct
Aminoacid dehydrogenase-like, N-terminal domain0Direct
Seven-hairpin glycosidases0Direct
Snake toxin-like0Direct
RNase III domain-like0Direct
Terpenoid synthases0Direct
Zn-binding ribosomal proteins0Direct
SAND domain-like0Direct
PYP-like sensor domain (PAS domain)0Direct
Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain0Direct
TIMP-like0Direct
JAB1/MPN domain0Direct
Succinyl-CoA synthetase domains0Direct
Class II aaRS ABD-related0Direct
Periplasmic binding protein-like I0Direct
Multidrug efflux transporter AcrB transmembrane domain0Direct
A DNA-binding domain in eukaryotic transcription factors0Direct
Conserved domain common to transcription factors TFIIS, elongin A, CRSP700Direct
Heat shock protein 70kD (HSP70), peptide-binding domain0Direct
ValRS/IleRS/LeuRS editing domain0Direct
ACT-like0Direct
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor0Direct
Zinc beta-ribbon0Direct
dsRNA-binding domain-like0Direct
DEATH domain0Direct
Plexin repeat0Direct
2Fe-2S ferredoxin-like0Direct
Nucleoporin domain0Direct
Retrovirus zinc finger-like domains0Direct
DEK C-terminal domain0Direct
Cysteine-rich DNA binding domain, (DM domain)0Direct
HRDC-like0Direct
Ribosomal L27 protein-like0Direct
Translation proteins SH3-like domain0Direct
L27 domain0Direct
SAICAR synthase-like0Direct
Hormone receptor domain0Direct
PapD-like0Direct
Homeodomain-like0.000002467Direct
ARM repeat0.0000182Direct
SH3-domain0.0000632Direct
Protein kinase-like (PK-like)0.0001282Direct
EGF/Laminin0.01287Inherited
Nucleotidylyl transferase0.06585Inherited
beta-sandwich domain of Sec23/240.07766Inherited
Cysteine-rich domain0.07766Inherited
PDZ domain-like0.0908Inherited
Leucine zipper domain0.09114Inherited
EF-hand0.1034Inherited
Cyclin-like0.1055Inherited
beta-beta-alpha zinc fingers0.1123Inherited
BRCT domain0.1232Inherited
Fibronectin type III0.1416Inherited
SNARE fusion complex0.1448Inherited
FYVE/PHD zinc finger0.1489Inherited
Concanavalin A-like lectins/glucanases0.1979Inherited
C2 domain (Calcium/lipid-binding domain, CaLB)0.2093Inherited
Tudor/PWWP/MBT0.2177Inherited
Periplasmic binding protein-like II0.2271Inherited
N-acetylmuramoyl-L-alanine amidase-like0.2305Inherited
Cysteine proteinases0.238Inherited
Chromo domain-like0.2739Inherited
HMG-box0.2903Inherited
Ankyrin repeat0.3077Inherited
Macro domain-like0.3598Inherited
SH2 domain0.3868Inherited
Growth factor receptor domain0.4172Inherited
P-loop containing nucleoside triphosphate hydrolases0.4245Inherited
Cystine-knot cytokines0.4659Inherited
POZ domain0.4776Inherited
SAM/Pointed domain0.4841Inherited
MIR domain0.4846Inherited
PAZ domain0.4846Inherited
Glucocorticoid receptor-like (DNA-binding domain)0.4892Inherited
Tubulin nucleotide-binding domain-like0.5323Inherited
Nicotinic receptor ligand binding domain-like0.6001Inherited
Neurotransmitter-gated ion-channel transmembrane pore0.6001Inherited
cAMP-binding domain-like0.6001Inherited
Cadherin-like0.6001Inherited
Voltage-gated potassium channels0.61Inherited
SCOP hierarchy in SUPERFAMILY0.646Inherited
Family A G protein-coupled receptor-like0.7196Inherited
SET domain0.7267Inherited
Immunoglobulin0.7734Inherited
Nucleotide cyclase0.8389Inherited
NAD(P)-binding Rossmann-fold domains0.9361Inherited
alpha/beta-Hydrolases1Inherited


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

(show details)
SCOP termFDR (all)Annotation (direct or inherited)
Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain0Direct
PAPS sulfotransferase0Direct
Hairy Orange domain0Direct
Reprolysin-like0Direct
Calmodulin-like0Direct
Prefoldin0Direct
First domain of FERM0Direct
Aquaporin-like0Direct
Tropomyosin0Direct
Ubiquitin activating enzymes (UBA)0Direct
Alcohol dehydrogenase-like, N-terminal domain0Direct
Sema domain0Direct
Ubiquitin carboxyl-terminal hydrolase UCH-L0Direct
Fibroblast growth factors (FGF)0Direct
Rhomboid-like0Direct
Phosphatidylinositol phosphate kinase IIbeta, PIPK IIbeta0Direct
Histone lysine methyltransferases0Direct
Heat shock protein 70kD (HSP70), peptide-binding domain0Direct
Group II chaperonin (CCT, TRIC), ATPase domain0Direct
GroEL chaperone, ATPase domain0Direct
Taf5 N-terminal domain-like0Direct
MAM domain0Direct
BC C-terminal domain-like0Direct
Single strand DNA-binding domain, SSB0Direct
Cell cycle transcription factor e2f-dp0Direct
PLC-like (P variant)0Direct
Clathrin coat assembly domain0Direct
A DNA-binding domain in eukaryotic transcription factors0Direct
RecA protein-like (ATPase-domain)0Direct
Inositol polyphosphate kinase (IPK)0Direct
Ferredoxin domains from multidomain proteins0Direct
PurM C-terminal domain-like0Direct
RUNT domain0Direct
Aminoacid dehydrogenase-like, C-terminal domain0Direct
Acyl-carrier protein (ACP)0Direct
Armadillo repeat0Direct
Cyclin0Direct
Transducin (alpha subunit), insertion domain0Direct
Ubiquitin carboxyl-terminal hydrolase, UCH0Direct
Alcohol dehydrogenase-like, C-terminal domain0Direct
Erythroid transcription factor GATA-10Direct
B-box zinc-binding domain0Direct
Transcriptional factor domain0Direct
XPF/Rad1/Mus81 nuclease0Direct
MIF4G domain-like0Direct
SMAD domain0Direct
T-box0Direct
Group II chaperonin (CCT, TRIC), intermediate domain0Direct
Forkhead DNA-binding domain0Direct
L27 domain0Direct
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor0Direct
Roadblock/LC7 domain0Direct
DEK C-terminal domain0Direct
Discoidin domain (FA58C, coagulation factor 5/8 C-terminal domain)0Direct
Regulator of G-protein signaling, RGS0Direct
beta-CASP RNA-metabolising hydrolases0Direct
2Fe-2S ferredoxin domains from multidomain proteins0Direct
Skp1 dimerisation domain-like0Direct
PurM N-terminal domain-like0Direct
Gelsolin-like0Direct
Leucine aminopeptidase (Aminopeptidase A), N-terminal domain0Direct
Sec1/munc18-like (SM) proteins0Direct
NF-kappa-B/REL/DORSAL transcription factors, C-terminal domain0Direct
Nop domain0Direct
Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit0Direct
SMAD MH1 domain0Direct
Myb/SANT domain0Direct
Retrovirus zinc finger-like domains0Direct
Neurolysin-like0Direct
Eps15 homology domain (EH domain)0Direct
Group II chaperonin (CCT, TRIC), apical domain0Direct
IF2B-like0Direct
Phoshoinositide 3-kinase (PI3K) helical domain0Direct
TBP-associated factors, TAFs0Direct
Transforming growth factor (TGF)-beta0Direct
a tRNA synthase domain0Direct
Hsp90 middle domain0Direct
Nuclear receptor0Direct
Cysteine-rich DNA binding domain, (DM domain)0Direct
BC ATP-binding domain-like0Direct
Insulin-like0Direct
C-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
Conserved domain common to transcription factors TFIIS, elongin A, CRSP700Direct
Sec7 domain0Direct
Extracellular domain of cell surface receptors0Direct
MBT repeat0Direct
Class I glutamine amidotransferases (GAT)0Direct
DEATH domain, DD0Direct
Hypoxia-inducible factor Hif2a, C-terminal domain0Direct
Smc hinge domain0Direct
N-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
Succinyl-CoA synthetase, beta-chain, N-terminal domain0Direct
Translational machinery components0Direct
Nitrogenase iron protein-like0Direct
Paired domain0Direct
Caspase catalytic domain0Direct
ARID domain0Direct
PX domain0Direct
Enabled/VASP homology 1 domain (EVH1 domain)0Direct
Sm motif of small nuclear ribonucleoproteins, SNRNP0Direct
Arrestin/Vps26-like0Direct
Laminin-type module0Direct
La domain0Direct
GroEL-like chaperone, intermediate domain0Direct
Subtilases0Direct
Hormone receptor domain0Direct
Rel/Dorsal transcription factors, DNA-binding domain0Direct
Zf-UBP0Direct
Astacin0Direct
Bromodomain0Direct
Spectrin repeat0Direct
Heat shock protein 90, HSP90, N-terminal domain0Direct
Ngr ectodomain-like0Direct
CBS-domain pair0Direct
C-terminal, gelsolin-like domain of Sec23/240Direct
Pointed domain0Direct
Histidine acid phosphatase0Direct
Heat shock protein 70kD (HSP70), C-terminal subdomain0Direct
HR1 repeat0Direct
Succinyl-CoA synthetase domains0Direct
Diap1 N-terninal region-like0Direct
GroEL-like chaperone, apical domain0Direct
Dimeric isocitrate & isopropylmalate dehydrogenases0Direct
RNase III catalytic domain-like0Direct
S-adenosylhomocystein hydrolase0Direct
Blood coagulation inhibitor (disintegrin)0Direct
Plexin repeat0Direct
Double-stranded RNA-binding domain (dsRBD)0Direct
CAD domain0Direct
GMC oxidoreductases0Direct
SAP domain0Direct
Chromo barrel domain0Direct
Phoshoinositide 3-kinase (PI3K), catalytic domain0Direct
BAR domain0Direct
POU-specific domain0Direct
Toll/Interleukin receptor TIR domain0Direct
Mob1/phocein0Direct
Calpain large subunit, catalytic domain (domain II)0Direct
Leucine aminopeptidase, C-terminal domain0Direct
Integrin domains0Direct
L-arabinose binding protein-like0Direct
ValRS/IleRS/LeuRS editing domain0Direct
Ribosomal protein L10Direct
Meta-cation ATPase, catalytic domain P0Direct
Penta-EF-hand proteins0Direct
Clathrin adaptor core protein0Direct
Aromatic aminoacid monoxygenases, catalytic and oligomerization domains0Direct
HLH, helix-loop-helix DNA-binding domain0Direct
BC N-terminal domain-like0Direct
Laminin G-like module0Direct
Anticodon-binding domain of Class II aaRS0Direct
FHA domain0Direct
Isoprenyl diphosphate synthases0Direct
ets domain0Direct
Cu,Zn superoxide dismutase-like0Direct
NHL repeat0Direct
Dachshund-homology domain0Direct
Nuclear receptor ligand-binding domain0Direct
H-NOX domain0Direct
Cell cycle control phosphatase, catalytic domain0Direct
ZZ domain0Direct
Formin homology 2 domain (FH2 domain)0Direct
MSP-like0Direct
TATA-box binding protein (TBP), C-terminal domain0Direct
Protein serine/threonine phosphatase0Direct
Multidrug efflux transporter AcrB transmembrane domain0Direct
Class I alpha-1;2-mannosidase, catalytic domain0Direct
Protein kinases, catalytic subunit0.000005168Direct
Homeodomain0.00002152Direct
SH3-domain0.0001415Direct
PDZ domain0.01808Inherited
Motor proteins0.02953Inherited
I set domains0.05501Inherited
EGF-type module0.07455Inherited
Tandem AAA-ATPase domain0.08922Inherited
Leucine zipper domain0.09996Inherited
Phosphate binding protein-like0.09996Inherited
Class I aminoacyl-tRNA synthetases (RS), catalytic domain0.1553Inherited
SAM (sterile alpha motif) domain0.1801Inherited
Fibronectin type III0.1934Inherited
PHD domain0.2259Inherited
Classic zinc finger, C2H20.2291Inherited
Dual specificity phosphatase-like0.2365Inherited
N-acetylmuramoyl-L-alanine amidase-like0.2365Inherited
Tetramerization domain of potassium channels0.364Inherited
Ankyrin repeat0.3943Inherited
Extended AAA-ATPase domain0.4026Inherited
Pancreatic lipase, N-terminal domain0.4217Inherited
Glutathione peroxidase-like0.4217Inherited
SH2 domain0.4331Inherited
Growth factor receptor domain0.4537Inherited
MIR domain0.4848Inherited
UBA domain0.4848Inherited
Synaptotagmin-like (S variant)0.4989Inherited
Tubulin, GTPase domain0.5555Inherited
PAZ domain0.5644Inherited
Rhodopsin-like0.5697Inherited
Neurotransmitter-gated ion-channel transmembrane pore0.6346Inherited
cAMP-binding domain0.6792Inherited
Cadherin0.6792Inherited
G proteins0.7127Inherited
Acetylcholinesterase-like0.7588Inherited
Nicotinic receptor ligand binding domain-like0.764Inherited
Voltage-gated potassium channels0.8193Inherited
Adenylyl and guanylyl cyclase catalytic domain0.8609Inherited
Neutral endopeptidase (neprilysin)0.9629Inherited


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Supra-domain (including individual superfamily)

(show details)
Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Zn-binding ribosomal proteins0Direct
Mob1/phocein0Direct
HSP90 C-terminal domain0Direct
PurM N-terminal domain-like0Direct
HRDC-like0Direct
ThrRS/AlaRS common domain0Direct
Translational machinery components0Direct
CAD & PB1 domains0Direct
KA1-like0Direct
RBP11-like subunits of RNA polymerase0Direct
PIN domain-like0Direct
HR1 repeat0Direct
Lipocalins0Direct
PapD-like0Direct
SAICAR synthase-like0Direct
Toll/Interleukin receptor TIR domain0Direct
Activating enzymes of the ubiquitin-like proteins0Direct
ARID-like0Direct
A DNA-binding domain in eukaryotic transcription factors0Direct
Sec1/munc18-like (SM) proteins0Direct
GINS helical bundle-like0Direct
TIMP-like0Direct
Ferritin-like0Direct
ACT-like0Direct
Sm-like ribonucleoproteins0Direct
beta and beta-prime subunits of DNA dependent RNA-polymerase0Direct
SAP domain0Direct
Aquaporin-like0Direct
Regulator of G-protein signaling, RGS0Direct
SPOC domain-like0Direct
Conserved domain common to transcription factors TFIIS, elongin A, CRSP700Direct
Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit0Direct
Hormone receptor domain0Direct
Ribosomal L27 protein-like0Direct
Taf5 N-terminal domain-like0Direct
SNARE-like0Direct
L27 domain0Direct
lambda repressor-like DNA-binding domains0Direct
DNA/RNA polymerases0Direct
Sema domain0Direct
Tetrahydrobiopterin biosynthesis enzymes-like0Direct
PYP-like sensor domain (PAS domain)0Direct
Rudiment single hybrid motif0Direct
YVTN repeat-like/Quinoprotein amine dehydrogenase0Direct
Insulin-like0Direct
TATA-box binding protein-like0Direct
4Fe-4S ferredoxins0Direct
Riboflavin synthase domain-like0Direct
Roadblock/LC7 domain0Direct
Prefoldin0Direct
Transducin (alpha subunit), insertion domain0Direct
DNA-binding domain0Direct
Cu,Zn superoxide dismutase-like0Direct
Nucleoporin domain0Direct
Bet v1-like0Direct
DEATH domain0Direct
Heat shock protein 70kD (HSP70), C-terminal subdomain0Direct
Succinyl-CoA synthetase domains0Direct
Class I glutamine amidotransferase-like0Direct
Putative DNA-binding domain0Direct
GroEL equatorial domain-like0Direct
E2F-DP heterodimerization region0Direct
Heat shock protein 70kD (HSP70), peptide-binding domain0Direct
Ferredoxin reductase-like, C-terminal NADP-linked domain0Direct
Formin homology 2 domain (FH2 domain)0Direct
Bromodomain0Direct
C-terminal, gelsolin-like domain of Sec23/240Direct
ValRS/IleRS/LeuRS editing domain0Direct
Isocitrate/Isopropylmalate dehydrogenase-like0Direct
Zinc beta-ribbon0Direct
Nop domain0Direct
Snake toxin-like0Direct
vWA-like0Direct
PurM C-terminal domain-like0Direct
2Fe-2S ferredoxin-like0Direct
GroEL-intermediate domain like0Direct
SMAD MH1 domain0Direct
Cysteine-rich DNA binding domain, (DM domain)0Direct
Blood coagulation inhibitor (disintegrin)0Direct
ACP-like0Direct
Plexin repeat0Direct
CBS-domain pair0Direct
Nuclear receptor ligand-binding domain0Direct
DEK C-terminal domain0Direct
SAND domain-like0Direct
PriA/YqbF domain0Direct
Translation proteins SH3-like domain0Direct
Retrovirus zinc finger-like domains0Direct
SMAD/FHA domain0Direct
C-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
Restriction endonuclease-like0Direct
RNase III domain-like0Direct
HLH, helix-loop-helix DNA-binding domain0Direct
Tropomyosin0Direct
Sec7 domain0Direct
Ribosomal protein L10Direct
Integrin domains0Direct
Cytokine0Direct
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor0Direct
GroEL apical domain-like0Direct
Periplasmic binding protein-like I0Direct
S15/NS1 RNA-binding domain0Direct
Aminoacid dehydrogenase-like, N-terminal domain0Direct
Aromatic aminoacid monoxygenases, catalytic and oligomerization domains0Direct
JAB1/MPN domain0Direct
Terpenoid synthases0Direct
Glutamine synthetase/guanido kinase0Direct
Pectin lyase-like0Direct
Aldolase0Direct
Subtilisin-like0Direct
Clathrin adaptor appendage domain0Direct
Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain0Direct
Smc hinge domain0Direct
N-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
Class II aaRS ABD-related0Direct
Caspase-like0Direct
Orange domain-like0Direct
PX domain0Direct
dsRNA-binding domain-like0Direct
Spectrin repeat0Direct
Skp1 dimerisation domain-like0Direct
B-box zinc-binding domain0Direct
Multidrug efflux transporter AcrB transmembrane domain0Direct
PreATP-grasp domain0Direct
Seven-hairpin glycosidases0Direct
Homeodomain-like0.000001832Direct
ARM repeat0.00001372Direct
SH3-domain0.00004799Direct
Protein kinase-like (PK-like)0.00009805Direct
"Winged helix" DNA-binding domain0.0009399Direct
EGF/Laminin0.01061Inherited
Nucleotidylyl transferase0.05664Inherited
p53-like transcription factors0.05664Inherited
beta-sandwich domain of Sec23/240.06706Inherited
Cysteine-rich domain0.06706Inherited
PDZ domain-like0.07896Inherited
Leucine zipper domain0.07931Inherited
EF-hand0.09042Inherited
Cyclin-like0.09191Inherited
beta-beta-alpha zinc fingers0.09791Inherited
BRCT domain0.1072Inherited
Fibronectin type III0.1239Inherited
SNARE fusion complex0.1267Inherited
FYVE/PHD zinc finger0.1306Inherited
Concanavalin A-like lectins/glucanases0.1753Inherited
C2 domain (Calcium/lipid-binding domain, CaLB)0.1853Inherited
Tudor/PWWP/MBT0.1935Inherited
Periplasmic binding protein-like II0.2019Inherited
N-acetylmuramoyl-L-alanine amidase-like0.205Inherited
Cysteine proteinases0.2125Inherited
Chromo domain-like0.2473Inherited
HMG-box0.2632Inherited
Ankyrin repeat0.2794Inherited
Macro domain-like0.3302Inherited
SH2 domain0.3556Inherited
Growth factor receptor domain0.3863Inherited
P-loop containing nucleoside triphosphate hydrolases0.3934Inherited
Cystine-knot cytokines0.434Inherited
POZ domain0.4455Inherited
SAM/Pointed domain0.4523Inherited
PAZ domain0.4527Inherited
MIR domain0.4527Inherited
Glucocorticoid receptor-like (DNA-binding domain)0.4571Inherited
Tubulin nucleotide-binding domain-like0.5004Inherited
cAMP-binding domain-like0.5688Inherited
Neurotransmitter-gated ion-channel transmembrane pore0.5688Inherited
Cadherin-like0.5688Inherited
Nicotinic receptor ligand binding domain-like0.5688Inherited
Voltage-gated potassium channels0.5787Inherited
Family A G protein-coupled receptor-like0.6931Inherited
SET domain0.7001Inherited
Immunoglobulin0.747Inherited
Nucleotide cyclase0.8168Inherited
NAD(P)-binding Rossmann-fold domains0.9209Inherited
alpha/beta-Hydrolases1Inherited

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
55550,50044
  • 55550 - SH2 domain
  • 50044 - SH3-domain
  • 0Direct
    101912,103575
  • 101912 - Sema domain
  • 103575 - Plexin repeat
  • 0Direct
    101288,50156
  • 101288 - L27 domain
  • 50156 - PDZ domain-like
  • 0Direct
    49265,48726
  • 49265 - Fibronectin type III
  • 48726 - Immunoglobulin
  • 0Direct
    49562,48371
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 48371 - ARM repeat
  • 0Direct
    54980,54211
  • 54980 - EF-G C-terminal domain-like
  • 54211 - Ribosomal protein S5 domain 2-like
  • 0Direct
    53067,100920
  • 53067 - Actin-like ATPase domain
  • 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
  • 0Direct
    46785,144074
  • 46785 - "Winged helix" DNA-binding domain
  • 144074 - E2F-DP heterodimerization region
  • 0Direct
    55550,56112
  • 55550 - SH2 domain
  • 56112 - Protein kinase-like (PK-like)
  • 0Direct
    46689,46689
  • 46689 - Homeodomain-like
  • 46689 - Homeodomain-like
  • 0Direct
    55021,56534
  • 55021 - ACT-like
  • 56534 - Aromatic aminoacid monoxygenases, catalytic and oligomerization domains
  • 0Direct
    57850,57850
  • 57850 - RING/U-box
  • 57850 - RING/U-box
  • 0Direct
    48425,50729
  • 48425 - Sec7 domain
  • 50729 - PH domain-like
  • 0Direct
    53223,51735
  • 53223 - Aminoacid dehydrogenase-like, N-terminal domain
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 0Direct
    49899,57196
  • 49899 - Concanavalin A-like lectins/glucanases
  • 57196 - EGF/Laminin
  • 0Direct
    63748,63748
  • 63748 - Tudor/PWWP/MBT
  • 63748 - Tudor/PWWP/MBT
  • 0Direct
    54791,54791
  • 54791 - Eukaryotic type KH-domain (KH-domain type I)
  • 54791 - Eukaryotic type KH-domain (KH-domain type I)
  • 0Direct
    50044,52540
  • 50044 - SH3-domain
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    55681,52954
  • 55681 - Class II aaRS and biotin synthetases
  • 52954 - Class II aaRS ABD-related
  • 0Direct
    52374,47323
  • 52374 - Nucleotidylyl transferase
  • 47323 - Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
  • 0Direct
    55326,56042
  • 55326 - PurM N-terminal domain-like
  • 56042 - PurM C-terminal domain-like
  • 0Direct
    49417,81296
  • 49417 - p53-like transcription factors
  • 81296 - E set domains
  • 0Direct
    50044,50044
  • 50044 - SH3-domain
  • 50044 - SH3-domain
  • 0Direct
    52540,47917
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 47917 - C-terminal domain of alpha and beta subunits of F1 ATP synthase
  • 0Direct
    54534,48452
  • 54534 - FKBP-like
  • 48452 - TPR-like
  • 0Direct
    56112,48371
  • 56112 - Protein kinase-like (PK-like)
  • 48371 - ARM repeat
  • 0Direct
    100920,100934
  • 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
  • 100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain
  • 0Direct
    48371,56112
  • 48371 - ARM repeat
  • 56112 - Protein kinase-like (PK-like)
  • 0Direct
    52058,48726
  • 52058 - L domain-like
  • 48726 - Immunoglobulin
  • 0Direct
    46785,54928
  • 46785 - "Winged helix" DNA-binding domain
  • 54928 - RNA-binding domain, RBD
  • 0Direct
    57716,48508
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 48508 - Nuclear receptor ligand-binding domain
  • 0Direct
    57903,57903
  • 57903 - FYVE/PHD zinc finger
  • 57903 - FYVE/PHD zinc finger
  • 0Direct
    46785,46785
  • 46785 - "Winged helix" DNA-binding domain
  • 46785 - "Winged helix" DNA-binding domain
  • 0Direct
    111418,81321
  • 111418 - Hormone receptor domain
  • 81321 - Family A G protein-coupled receptor-like
  • 0Direct
    57196,49899
  • 57196 - EGF/Laminin
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0Direct
    57903,47370
  • 57903 - FYVE/PHD zinc finger
  • 47370 - Bromodomain
  • 0Direct
    52949,53187
  • 52949 - Macro domain-like
  • 53187 - Zn-dependent exopeptidases
  • 0Direct
    57196,49854
  • 57196 - EGF/Laminin
  • 49854 - Spermadhesin, CUB domain
  • 0Direct
    46966,46966
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 0Direct
    57184,57184
  • 57184 - Growth factor receptor domain
  • 57184 - Growth factor receptor domain
  • 0Direct
    47459,158457
  • 47459 - HLH, helix-loop-helix DNA-binding domain
  • 158457 - Orange domain-like
  • 0Direct
    50615,52540
  • 50615 - N-terminal domain of alpha and beta subunits of F1 ATP synthase
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    50044,55550
  • 50044 - SH3-domain
  • 55550 - SH2 domain
  • 0Direct
    47459,55785
  • 47459 - HLH, helix-loop-helix DNA-binding domain
  • 55785 - PYP-like sensor domain (PAS domain)
  • 0Direct
    56059,52210
  • 56059 - Glutathione synthetase ATP-binding domain-like
  • 52210 - Succinyl-CoA synthetase domains
  • 0Direct
    50677,52374
  • 50677 - ValRS/IleRS/LeuRS editing domain
  • 52374 - Nucleotidylyl transferase
  • 0Direct
    50156,50044
  • 50156 - PDZ domain-like
  • 50044 - SH3-domain
  • 0Direct
    55753,55753
  • 55753 - Actin depolymerizing proteins
  • 55753 - Actin depolymerizing proteins
  • 0Direct
    52058,52058
  • 52058 - L domain-like
  • 52058 - L domain-like
  • 0Direct
    54849,52029
  • 54849 - GroEL-intermediate domain like
  • 52029 - GroEL apical domain-like
  • 0Direct
    47413,46689
  • 47413 - lambda repressor-like DNA-binding domains
  • 46689 - Homeodomain-like
  • 0Direct
    48592,54849
  • 48592 - GroEL equatorial domain-like
  • 54849 - GroEL-intermediate domain like
  • 0Direct
    54236,47031
  • 54236 - Ubiquitin-like
  • 47031 - Second domain of FERM
  • 0Direct
    57889,57889
  • 57889 - Cysteine-rich domain
  • 57889 - Cysteine-rich domain
  • 0Direct
    55486,57552
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 57552 - Blood coagulation inhibitor (disintegrin)
  • 0Direct
    57716,46689
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 46689 - Homeodomain-like
  • 0Direct
    52440,56059
  • 52440 - PreATP-grasp domain
  • 56059 - Glutathione synthetase ATP-binding domain-like
  • 0Direct
    55945,55945
  • 55945 - TATA-box binding protein-like
  • 55945 - TATA-box binding protein-like
  • 0Direct
    57184,57196
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 0Direct
    54768,54768
  • 54768 - dsRNA-binding domain-like
  • 54768 - dsRNA-binding domain-like
  • 0Direct
    54695,81382
  • 54695 - POZ domain
  • 81382 - Skp1 dimerisation domain-like
  • 0Direct
    47895,52540
  • 47895 - Transducin (alpha subunit), insertion domain
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    47954,47954
  • 47954 - Cyclin-like
  • 47954 - Cyclin-like
  • 0Direct
    56059,51246
  • 56059 - Glutathione synthetase ATP-binding domain-like
  • 51246 - Rudiment single hybrid motif
  • 0Direct
    52113,52113
  • 52113 - BRCT domain
  • 52113 - BRCT domain
  • 0Direct
    54211,54980
  • 54211 - Ribosomal protein S5 domain 2-like
  • 54980 - EF-G C-terminal domain-like
  • 0Direct
    49265,49265
  • 49265 - Fibronectin type III
  • 49265 - Fibronectin type III
  • 0Direct
    57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.1488Inherited
    50978,50978
  • 50978 - WD40 repeat-like
  • 50978 - WD40 repeat-like
  • 0.205Inherited
    48726,49265
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 0.2125Inherited
    51045,51045
  • 51045 - WW domain
  • 51045 - WW domain
  • 0.241Inherited
    48726,48726
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 0.3077Inherited
    57667,57667
  • 57667 - beta-beta-alpha zinc fingers
  • 57667 - beta-beta-alpha zinc fingers
  • 0.3483Inherited
    49899,49899
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.3566Inherited
    48403,48403
  • 48403 - Ankyrin repeat
  • 48403 - Ankyrin repeat
  • 0.3863Inherited
    57196,57184
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 0.3863Inherited
    101690,53098
  • 101690 - PAZ domain
  • 53098 - Ribonuclease H-like
  • 0.5338Inherited
    63712,90112
  • 63712 - Nicotinic receptor ligand binding domain-like
  • 90112 - Neurotransmitter-gated ion-channel transmembrane pore
  • 0.5688Inherited
    52540,52540
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.6421Inherited
    49313,49313
  • 49313 - Cadherin-like
  • 49313 - Cadherin-like
  • 0.6664Inherited
    57625,57625
  • 57625 - Invertebrate chitin-binding proteins
  • 57625 - Invertebrate chitin-binding proteins
  • 0.7445Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    57196,57184,57196
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 0Direct
    101288,50156,50044
  • 101288 - L27 domain
  • 50156 - PDZ domain-like
  • 50044 - SH3-domain
  • 0Direct
    57196,49899,49899
  • 57196 - EGF/Laminin
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0Direct
    57184,57196,57196
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0Direct
    48592,54849,52029
  • 48592 - GroEL equatorial domain-like
  • 54849 - GroEL-intermediate domain like
  • 52029 - GroEL apical domain-like
  • 0Direct
    81296,81296,81296
  • 81296 - E set domains
  • 81296 - E set domains
  • 81296 - E set domains
  • 0Direct
    50615,52540,47917
  • 50615 - N-terminal domain of alpha and beta subunits of F1 ATP synthase
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 47917 - C-terminal domain of alpha and beta subunits of F1 ATP synthase
  • 0Direct
    53067,100920,100934
  • 53067 - Actin-like ATPase domain
  • 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
  • 100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain
  • 0Direct
    52058,52058,52058
  • 52058 - L domain-like
  • 52058 - L domain-like
  • 52058 - L domain-like
  • 0Direct
    53067,53067,100920
  • 53067 - Actin-like ATPase domain
  • 53067 - Actin-like ATPase domain
  • 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
  • 0Direct
    49899,49899,49899
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0Direct
    49265,48726,48726
  • 49265 - Fibronectin type III
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 0Direct
    49562,48371,56112
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 48371 - ARM repeat
  • 56112 - Protein kinase-like (PK-like)
  • 0Direct
    50156,50044,52540
  • 50156 - PDZ domain-like
  • 50044 - SH3-domain
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    49899,57196,57196
  • 49899 - Concanavalin A-like lectins/glucanases
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0Direct
    54236,47031,50729
  • 54236 - Ubiquitin-like
  • 47031 - Second domain of FERM
  • 50729 - PH domain-like
  • 0Direct
    46966,46966,46966
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 0Direct
    52440,56059,51246
  • 52440 - PreATP-grasp domain
  • 56059 - Glutathione synthetase ATP-binding domain-like
  • 51246 - Rudiment single hybrid motif
  • 0Direct
    55753,55753,55753
  • 55753 - Actin depolymerizing proteins
  • 55753 - Actin depolymerizing proteins
  • 55753 - Actin depolymerizing proteins
  • 0Direct
    57850,57850,57850
  • 57850 - RING/U-box
  • 57850 - RING/U-box
  • 57850 - RING/U-box
  • 0Direct
    54980,54211,54980
  • 54980 - EF-G C-terminal domain-like
  • 54211 - Ribosomal protein S5 domain 2-like
  • 54980 - EF-G C-terminal domain-like
  • 0Direct
    48452,48452,48452
  • 48452 - TPR-like
  • 48452 - TPR-like
  • 48452 - TPR-like
  • 0Direct
    48726,48726,49265
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 0.04041Inherited
    57196,57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.1267Inherited
    48726,48726,48726
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 0.2122Inherited
    52540,52540,52540
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.2821Inherited
    48371,48371,48371
  • 48371 - ARM repeat
  • 48371 - ARM repeat
  • 48371 - ARM repeat
  • 0.3863Inherited
    57625,57625,57625
  • 57625 - Invertebrate chitin-binding proteins
  • 57625 - Invertebrate chitin-binding proteins
  • 57625 - Invertebrate chitin-binding proteins
  • 0.4527Inherited
    49313,49313,49313
  • 49313 - Cadherin-like
  • 49313 - Cadherin-like
  • 49313 - Cadherin-like
  • 0.7145Inherited
    57667,57667,57667
  • 57667 - beta-beta-alpha zinc fingers
  • 57667 - beta-beta-alpha zinc fingers
  • 57667 - beta-beta-alpha zinc fingers
  • 0.7872Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
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