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Phenotypic Abnormality (PA): Constitutional symptom

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Root: HP Hierarchy (human phenotype with 3 sub-ontologies PA, MI, ON)

Shortest distance to current term (+ for parents, - for children) HP term [HP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ 1:   Phenotypic abnormality [HP:0000118] <25>
0:   Constitutional symptom [HP:0025142] <12>(4|10) (7|3|0)
- 1:   Pain [HP:0012531] <35>(3|10) (6|3|0)
- 1:   Impairment of activities of daily living [HP:0031058] <6>(0|0) (0|0|0)
- 1:   Fatigue [HP:0012378] <3>(2|4) (2|2|0)
- 1:   Body odor [HP:0500001] <2>(0|0) (0|0|0)
- 1:   Chills [HP:0025143] <1>(0|0) (0|0|0)
- 1:   Halitosis [HP:0100812] <1>(0|0) (0|0|0)
- 1:   Shivering [HP:0025144] <1>(0|0) (0|0|0)
- 1:   Asthenia [HP:0025406](0|0) (0|0|0)
- 1:   Chest tightness [HP:0031352](0|0) (0|0|0)
- 1:   Gangrene [HP:0100758](0|0) (0|0|0)
- 1:   Hot flashes [HP:0031217](0|0) (0|0|0)
- 1:   Night sweats [HP:0030166](0|0) (0|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
DEATH domain0.004581Inherited
Calcium-dependent phosphotriesterase0.01261Inherited
MHC antigen-recognition domain0.01946Inherited
RNI-like0.1221Inherited


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Family

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SCOP termFDR (all)Annotation (direct or inherited)
Serum paraoxonase/arylesterase 1, PON10Direct
Proteasome subunits0Direct
DNA gyrase/MutL, second domain0.002574Inherited
DNA gyrase/MutL, N-terminal domain0.002574Inherited
C1 set domains (antibody constant domain-like)0.004236Inherited
MHC antigen-recognition domain0.01575Inherited
Pyrin domain, PYD0.02845Inherited
Adenosine/AMP deaminase0.02845Inherited
28-residue LRR0.09157Inherited
LDL receptor-like module0.4336Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
DEATH domain0.002826Inherited
Calcium-dependent phosphotriesterase0.008387Inherited
MHC antigen-recognition domain0.01339Inherited
Metallo-dependent hydrolases0.08279Inherited
N-terminal nucleophile aminohydrolases (Ntn hydrolases)0.08279Inherited
RNI-like0.09822Inherited
LDL receptor-like module0.3981Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
55874,54211
  • 55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
  • 54211 - Ribosomal protein S5 domain 2-like
  • 0.002153Inherited
    47986,52540
  • 47986 - DEATH domain
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.002153Inherited
    54452,48726
  • 54452 - MHC antigen-recognition domain
  • 48726 - Immunoglobulin
  • 0.01339Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
    (show help)