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Phenotypic Abnormality (PA): Abnormality of the kidney

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Root: HP Hierarchy (human phenotype with 3 sub-ontologies PA, MI, ON)

Shortest distance to current term (+ for parents, - for children) HP term [HP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + 4:   Phenotypic abnormality [HP:0000118] <25>
+ + + 3:   Abnormality of the genitourinary system [HP:0000119] <5>(72|74) (80|28|7)
+ + 2:   Abnormality of the urinary system [HP:0000079] <4>(36|39) (42|14|6)
+ 1:   Abnormality of the upper urinary tract [HP:0010935] <2>(21|23) (22|9|4)
0:   Abnormality of the kidney [HP:0000077] <3>(17|17) (18|8|4)
- 1:   Abnormal renal morphology [HP:0012210] <26>(14|11) (15|4|1)
- 1:   Abnormal renal physiology [HP:0012211] <15>(9|11) (10|5|2)
- 1:   Renal neoplasm [HP:0009726] <8>(0|0) (0|0|1)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
PRTase-like0Direct
Tricorn protease domain 20Direct
Transcription factor STAT-4 N-domain0.008469Inherited
STAT0.008469Inherited
WD40 repeat-like0.01127Inherited
HMG-box0.03851Inherited
Cysteine-rich domain0.04409Inherited
GroEL equatorial domain-like0.06271Inherited
Acyl-CoA N-acyltransferases (Nat)0.06271Inherited
ARID-like0.1127Inherited
MHC antigen-recognition domain0.1327Inherited
Cytokine0.3403Inherited
TNF-like0.3951Inherited
TPR-like0.4352Inherited
E set domains0.7728Inherited
L domain-like0.8491Inherited
C-type lectin-like0.8491Inherited


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Family

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SCOP termFDR (all)Annotation (direct or inherited)
Phosphoribosyltransferases (PRTases)0Direct
Cystathionine synthase-like0Direct
Transcription factor STAT-4 N-domain0.00584Inherited
STAT DNA-binding domain0.00584Inherited
STAT0.00584Inherited
Noncollagenous (NC1) domain of collagen IV0.01983Inherited
HMG-box0.03052Inherited
Protein kinase cysteine-rich domain (cys2, phorbol-binding domain)0.04509Inherited
ARID domain0.09457Inherited
MHC antigen-recognition domain0.113Inherited
Cytoplasmic domain of inward rectifier potassium channel0.113Inherited
C1 set domains (antibody constant domain-like)0.1207Inherited
WD40-repeat0.1919Inherited
Fibroblast growth factors (FGF)0.2056Inherited
TNF-like0.3664Inherited
Ngr ectodomain-like0.5304Inherited
Voltage-gated potassium channels0.8894Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
PRTase-like0Direct
Tricorn protease domain 20Direct
STAT0.005509Inherited
Transcription factor STAT-4 N-domain0.005509Inherited
WD40 repeat-like0.007446Inherited
HMG-box0.02807Inherited
Cysteine-rich domain0.03245Inherited
GroEL equatorial domain-like0.04767Inherited
Acyl-CoA N-acyltransferases (Nat)0.04767Inherited
ARID-like0.09002Inherited
MHC antigen-recognition domain0.1076Inherited
Cytokine0.3004Inherited
TNF-like0.3536Inherited
TPR-like0.3928Inherited
PDZ domain-like0.479Inherited
E set domains0.7379Inherited
C-type lectin-like0.8175Inherited
L domain-like0.8175Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
48092,47655
  • 48092 - Transcription factor STAT-4 N-domain
  • 47655 - STAT
  • 0.005509Inherited
    49417,55550
  • 49417 - p53-like transcription factors
  • 55550 - SH2 domain
  • 0.005509Inherited
    47655,49417
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 0.005509Inherited
    50978,50978
  • 50978 - WD40 repeat-like
  • 50978 - WD40 repeat-like
  • 0.006775Inherited
    57903,57903
  • 57903 - FYVE/PHD zinc finger
  • 57903 - FYVE/PHD zinc finger
  • 0.01882Inherited
    56436,56436
  • 56436 - C-type lectin-like
  • 56436 - C-type lectin-like
  • 0.07027Inherited
    81324,81296
  • 81324 - Voltage-gated potassium channels
  • 81296 - E set domains
  • 0.1076Inherited
    54452,48726
  • 54452 - MHC antigen-recognition domain
  • 48726 - Immunoglobulin
  • 0.1076Inherited

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    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    48092,47655,49417
  • 48092 - Transcription factor STAT-4 N-domain
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 0.005509Inherited
    47655,49417,55550
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 55550 - SH2 domain
  • 0.005509Inherited
    49265,49265,49265
  • 49265 - Fibronectin type III
  • 49265 - Fibronectin type III
  • 49265 - Fibronectin type III
  • 0.1496Inherited
    57196,57196,57184
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 0.888Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
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