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Phenotypic Abnormality (PA): Abnormality of the ear

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Root: HP Hierarchy (human phenotype with 3 sub-ontologies PA, MI, ON)

Shortest distance to current term (+ for parents, - for children) HP term [HP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ 1:   Phenotypic abnormality [HP:0000118] <25>
0:   Abnormality of the ear [HP:0000598] <2>(18|30) (22|10|7)
- 1:   Abnormal ear morphology [HP:0031703] <5>(14|23) (17|8|7)
- 1:   Abnormal ear physiology [HP:0031704] <2>(8|10) (10|4|6)


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
Lamin A/C globular tail domain0Direct
Toll/Interleukin receptor TIR domain0Direct
Smc hinge domain0Direct
4Fe-4S ferredoxins0Direct
RuvA domain 2-like0Direct
FabD/lysophospholipase-like0Direct
JAB1/MPN domain0Direct
Ribonuclease PH domain 2-like0Direct
Sema domain0Direct
ADC-like0Direct
MIR domain0.03069Inherited
GroEL equatorial domain-like0.05658Inherited
SET domain0.06201Inherited
Bromodomain0.09025Inherited
Integrin domains0.1039Inherited
Acyl-CoA N-acyltransferases (Nat)0.2239Inherited
Cysteine-rich domain0.323Inherited
Family A G protein-coupled receptor-like0.808Inherited


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

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SCOP termFDR (all)Annotation (direct or inherited)
XPF/Rad1/Mus81 nuclease0Direct
Lamin A/C globular tail domain0Direct
JAB1/MPN domain0Direct
Toll/Interleukin receptor TIR domain0Direct
Ferredoxin domains from multidomain proteins0Direct
beta-glycanases0Direct
Smc hinge domain0Direct
Lipoxigenase N-terminal domain0Direct
Ribonuclease PH domain 1-like0Direct
RhoGDI-like0Direct
Ribonuclease PH domain 2-like0Direct
Sema domain0Direct
Enabled/VASP homology 1 domain (EVH1 domain)0Direct
Histone deacetylase, HDAC0Direct
Plexin repeat0.003065Inherited
VWC domain0.01082Inherited
Arylsulfatase0.01125Inherited
ARID domain0.02155Inherited
MIR domain0.02155Inherited
PHD domain0.02284Inherited
Histone lysine methyltransferases0.04968Inherited
Bromodomain0.07019Inherited
Rel/Dorsal transcription factors, DNA-binding domain0.08121Inherited
Integrin domains0.08214Inherited
NF-kappa-B/REL/DORSAL transcription factors, C-terminal domain0.114Inherited
G proteins0.1252Inherited
C1 set domains (antibody constant domain-like)0.1469Inherited
Protein kinase cysteine-rich domain (cys2, phorbol-binding domain)0.2907Inherited
Rhodopsin-like0.8178Inherited
Pleckstrin-homology domain (PH domain)0.9362Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
4Fe-4S ferredoxins0Direct
ADC-like0Direct
JAB1/MPN domain0Direct
Sema domain0Direct
Ribonuclease PH domain 2-like0Direct
Smc hinge domain0Direct
FabD/lysophospholipase-like0Direct
Toll/Interleukin receptor TIR domain0Direct
Lamin A/C globular tail domain0Direct
RuvA domain 2-like0Direct
Plexin repeat0.003159Inherited
MIR domain0.02198Inherited
ARID-like0.02198Inherited
SNARE fusion complex0.04267Inherited
GroEL equatorial domain-like0.04267Inherited
SET domain0.0471Inherited
Bromodomain0.07082Inherited
Notch domain0.08086Inherited
Integrin domains0.08248Inherited
Acyl-CoA N-acyltransferases (Nat)0.1902Inherited
Cysteine-rich domain0.2839Inherited
Family A G protein-coupled receptor-like0.7748Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
101912,103575
  • 101912 - Sema domain
  • 103575 - Plexin repeat
  • 0Direct
    52799,52799
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 0Direct
    103575,48726
  • 103575 - Plexin repeat
  • 48726 - Immunoglobulin
  • 0Direct
    54211,55666
  • 54211 - Ribosomal protein S5 domain 2-like
  • 55666 - Ribonuclease PH domain 2-like
  • 0Direct
    64268,50044
  • 64268 - PX domain
  • 50044 - SH3-domain
  • 0Direct
    52980,47781
  • 52980 - Restriction endonuclease-like
  • 47781 - RuvA domain 2-like
  • 0Direct
    141072,141072
  • 141072 - CalX-like
  • 141072 - CalX-like
  • 0Direct
    53300,53300
  • 53300 - vWA-like
  • 53300 - vWA-like
  • 0.04267Inherited
    49417,81296
  • 49417 - p53-like transcription factors
  • 81296 - E set domains
  • 0.08086Inherited
    57903,57903
  • 57903 - FYVE/PHD zinc finger
  • 57903 - FYVE/PHD zinc finger
  • 0.1147Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    101912,103575,48726
  • 101912 - Sema domain
  • 103575 - Plexin repeat
  • 48726 - Immunoglobulin
  • 0Direct
    141072,141072,141072
  • 141072 - CalX-like
  • 141072 - CalX-like
  • 141072 - CalX-like
  • 0Direct
    57184,57196,57184
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 0Direct
    49899,57196,49899
  • 49899 - Concanavalin A-like lectins/glucanases
  • 57196 - EGF/Laminin
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0Direct
    57196,57184,57196
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 0.06721Inherited
    57196,57196,57184
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 0.09306Inherited
    57184,57196,57196
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.1324Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
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