SUPERFAMILY 1.75 HMM library and genome assignments server

Superfamily is undergoing a server migration - you are now browsing on the new server. Please contact us if you experience any problems.

Phenotypic Abnormality (PA): Abnormality of finger

(show info)

Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Root: HP Hierarchy (human phenotype with 3 sub-ontologies PA, MI, ON)

Shortest distance to current term (+ for parents, - for children) HP term [HP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + 4:   Abnormality of the skeletal system [HP:0000924] <7>(88|98) (93|54|34)
+ + + + 4:   Abnormality of skeletal morphology [HP:0011842] <17>(86|89) (90|52|33)
+ + + + 4:   Phenotypic abnormality [HP:0000118] <25>
+ + + 3:   Abnormal appendicular skeleton morphology [HP:0011844] <4>(35|42) (39|23|23)
+ + + 3:   Abnormality of limbs [HP:0040064] <8>(58|65) (63|33|25)
+ + + 3:   Abnormality of limb bone [HP:0040068] <1>(29|31) (33|18|20)
+ + 2:   Abnormality of limb bone morphology [HP:0002813] <13>(29|31) (32|18|20)
+ + 2:   Abnormality of the upper limb [HP:0002817] <20>(29|34) (35|17|16)
+ 1:   Abnormal digit morphology [HP:0011297] <10>(16|20) (18|14|16)
+ 1:   Abnormality of the hand [HP:0001155] <26>(22|26) (27|15|14)
0:   Abnormality of finger [HP:0001167] <24>(12|15) (13|9|10)
- 1:   Abnormal finger phalanx morphology [HP:0005918] <24>(8|9) (8|6|3)
- 1:   Aplasia/Hypoplasia of fingers [HP:0006265] <9>(2|2) (2|1|3)
- 1:   Deviation of finger [HP:0004097] <9>(1|2) (1|0|0)
- 1:   Abnormal 5th finger morphology [HP:0004207] <8>(4|3) (4|0|0)
- 1:   Abnormal thumb morphology [HP:0001172] <8>(1|4) (2|5|6)
- 1:   Abnormal 2nd finger morphology [HP:0004100] <6>(1|1) (1|0|0)
- 1:   Abnormal 3rd finger morphology [HP:0004150] <6>(0|0) (0|0|0)
- 1:   Abnormal 4th finger morphology [HP:0004188] <6>(0|0) (0|0|0)
- 1:   Curved fingers [HP:0004095] <5>(0|0) (0|0|0)
- 1:   Abnormal fingertip morphology [HP:0001211] <3>(0|0) (0|0|1)
- 1:   Abnormal finger flexion creases [HP:0006143] <2>(0|0) (0|0|0)
- 1:   Finger joint hypermobility [HP:0006094] <2>(1|1) (1|1|0)
- 1:   Long fingers [HP:0100807] <2>(0|1) (0|0|0)
- 1:   Broad finger [HP:0001500] <1>(0|0) (0|0|0)
- 1:   Slender finger [HP:0001238] <1>(0|1) (1|1|0)
- 1:   Chilblains [HP:0009710](0|0) (0|0|0)
- 1:   Finger dactylitis [HP:0031090](0|0) (0|0|0)
- 1:   Finger swelling [HP:0025131](1|1) (1|0|0)
- 1:   Macrodactyly of finger [HP:0100746](0|0) (0|0|0)
- 1:   Mallet finger [HP:0030771](0|0) (0|0|0)
- 1:   Spindle-shaped finger [HP:0031092](0|0) (0|0|0)
- 1:   Splayed fingers [HP:0030029](0|0) (0|0|0)
- 1:   Swan neck-like deformities of the fingers [HP:0006150](0|0) (0|0|0)
- 1:   Trident hand [HP:0004060](0|0) (0|0|0)


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Superfamily

(show details)
SCOP termFDR (all)Annotation (direct or inherited)
RuvA domain 2-like0Direct
Restriction endonuclease-like0.01686Inherited
Insulin-like0.01686Inherited
ARID-like0.01739Inherited
Multidrug efflux transporter AcrB transmembrane domain0.04545Inherited
WD40 repeat-like0.06109Inherited
HLH, helix-loop-helix DNA-binding domain0.06125Inherited
Cystine-knot cytokines0.2308Inherited
HMG-box0.3816Inherited
N-terminal nucleophile aminohydrolases (Ntn hydrolases)0.4244Inherited
GroEL equatorial domain-like0.4244Inherited
vWA-like0.5112Inherited


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

(show details)
SCOP termFDR (all)Annotation (direct or inherited)
XPF/Rad1/Mus81 nuclease0Direct
Proteasome subunits0Direct
Erythroid transcription factor GATA-10.0002086Direct
Actin/HSP700.0003018Direct
Insulin-like0.01093Inherited
ARID domain0.01117Inherited
HLH, helix-loop-helix DNA-binding domain0.04381Inherited
Transforming growth factor (TGF)-beta0.09131Inherited
RecA protein-like (ATPase-domain)0.1013Inherited
Classic zinc finger, C2H20.1487Inherited
I set domains0.2491Inherited
VWC domain0.301Inherited
Integrin A (or I) domain0.3394Inherited
HMG-box0.3394Inherited
TB module/8-cys domain0.6568Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
Plot tree as:   Download Newick format tree:
(show help)

Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

(show details)
Supra-domain (Single) FDR (all) Annotation (direct or inherited)
RuvA domain 2-like0Direct
Insulin-like0.01132Inherited
Restriction endonuclease-like0.01132Inherited
ARID-like0.0117Inherited
Multidrug efflux transporter AcrB transmembrane domain0.03315Inherited
WD40 repeat-like0.04594Inherited
HLH, helix-loop-helix DNA-binding domain0.04606Inherited
Cystine-knot cytokines0.1956Inherited
HMG-box0.3387Inherited
N-terminal nucleophile aminohydrolases (Ntn hydrolases)0.3807Inherited
GroEL equatorial domain-like0.3807Inherited
vWA-like0.4667Inherited
TB module/8-cys domain0.6523Inherited

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
52980,47781
  • 52980 - Restriction endonuclease-like
  • 47781 - RuvA domain 2-like
  • 0Direct
    103575,48726
  • 103575 - Plexin repeat
  • 48726 - Immunoglobulin
  • 0.01132Inherited
    53300,53300
  • 53300 - vWA-like
  • 53300 - vWA-like
  • 0.03315Inherited
    50729,50729
  • 50729 - PH domain-like
  • 50729 - PH domain-like
  • 0.1042Inherited
    57196,57184
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 0.1167Inherited
    57667,57667
  • 57667 - beta-beta-alpha zinc fingers
  • 57667 - beta-beta-alpha zinc fingers
  • 0.1756Inherited
    57903,57903
  • 57903 - FYVE/PHD zinc finger
  • 57903 - FYVE/PHD zinc finger
  • 0.3807Inherited
    57196,57581
  • 57196 - EGF/Laminin
  • 57581 - TB module/8-cys domain
  • 0.6523Inherited
    57581,57196
  • 57581 - TB module/8-cys domain
  • 57196 - EGF/Laminin
  • 0.6523Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    57184,57184,57196
  • 57184 - Growth factor receptor domain
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 0Direct
    57196,57581,57196
  • 57196 - EGF/Laminin
  • 57581 - TB module/8-cys domain
  • 57196 - EGF/Laminin
  • 0Direct
    57196,57581,57184
  • 57196 - EGF/Laminin
  • 57581 - TB module/8-cys domain
  • 57184 - Growth factor receptor domain
  • 0Direct
    57196,57196,57581
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 57581 - TB module/8-cys domain
  • 0Direct
    101912,103575,48726
  • 101912 - Sema domain
  • 103575 - Plexin repeat
  • 48726 - Immunoglobulin
  • 0.01132Inherited
    57196,57196,57184
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 0.1472Inherited
    57196,57184,57184
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 57184 - Growth factor receptor domain
  • 0.1866Inherited
    52540,52540,52540
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.3002Inherited
    57581,57196,57196
  • 57581 - TB module/8-cys domain
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.6523Inherited
    57581,57196,57581
  • 57581 - TB module/8-cys domain
  • 57196 - EGF/Laminin
  • 57581 - TB module/8-cys domain
  • 0.6523Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
    (show help)