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Phenotypic Abnormality (PA): Abnormal lung morphology

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Root: HP Hierarchy (human phenotype with 3 sub-ontologies PA, MI, ON)

Shortest distance to current term (+ for parents, - for children) HP term [HP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + 3:   Phenotypic abnormality [HP:0000118] <25>
+ + 2:   Abnormality of the respiratory system [HP:0002086] <3>(30|30) (33|19|17)
+ 1:   Abnormal respiratory system morphology [HP:0012252] <5>(21|21) (23|14|14)
0:   Abnormal lung morphology [HP:0002088] <28>(12|14) (15|8|4)
- 1:   Interstitial pulmonary abnormality [HP:0006530] <10>(0|0) (0|0|0)
- 1:   Neoplasm of the lung [HP:0100526] <9>(2|0) (2|0|0)
- 1:   Abnormal pulmonary thoracic imaging finding [HP:0031983] <7>(0|0) (0|0|0)
- 1:   Abnormality of the pleura [HP:0002103] <7>(2|4) (2|1|0)
- 1:   Abnormality of the pulmonary vasculature [HP:0004930] <6>(1|0) (3|2|3)
- 1:   Pulmonary cyst [HP:0032445] <5>(0|0) (0|0|0)
- 1:   Aplasia/Hypoplasia of the lungs [HP:0006703] <3>(0|0) (0|0|0)
- 1:   Pneumothorax [HP:0002107] <3>(0|1) (0|0|0)
- 1:   Respiratory tract infection [HP:0011947] <3>(2|6) (3|3|0)
- 1:   Abnormal lung lobation [HP:0002101] <2>(0|0) (0|0|0)
- 1:   Abnormal subpleural morphology [HP:0031630] <2>(0|0) (0|0|0)
- 1:   Bronchopulmonary sequestration [HP:0010960] <2>(0|0) (0|0|0)
- 1:   Pulmonary hemorrhage [HP:0040223] <2>(1|0) (1|0|0)
- 1:   Pulmonary infiltrates [HP:0002113] <2>(2|2) (2|1|0)
- 1:   Abnormal pulmonary lymphatics [HP:0006529] <1>(0|0) (0|0|0)
- 1:   Pulmonary fibrosis [HP:0002206] <1>(0|0) (0|0|0)
- 1:   Pulmonary opacity [HP:0031457] <1>(0|0) (0|0|0)
- 1:   Alveolar proteinosis [HP:0006517](0|0) (0|0|0)
- 1:   Atelectasis [HP:0100750](0|0) (0|0|0)
- 1:   Chronic lung disease [HP:0006528](0|0) (0|0|0)
- 1:   Emphysema [HP:0002097](1|1) (1|1|0)
- 1:   Hypersensitivity pneumonitis [HP:0006516](0|0) (0|0|0)
- 1:   Intraalveolar nodular calcifications [HP:0006514](0|0) (0|0|0)
- 1:   Lung abscess [HP:0025044](0|0) (0|0|0)
- 1:   Pulmonary edema [HP:0100598](0|0) (0|0|0)
- 1:   Pulmonary eosinophilic infiltration [HP:0032071](0|0) (0|0|0)
- 1:   Pulmonary granulomatosis [HP:0030250](0|0) (0|0|0)
- 1:   Unilateral primary pulmonary dysgenesis [HP:0006549](0|0) (0|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
Saposin0Direct
Tricorn protease domain 20Direct
Notch domain0Direct
DEATH domain0.0004616Direct
4-helical cytokines0.01429Inherited
MHC antigen-recognition domain0.02004Inherited
TNF receptor-like0.02364Inherited
Protein kinase-like (PK-like)0.1675Inherited
Immunoglobulin0.3946Inherited
ABC transporter transmembrane region0.4493Inherited
Ubiquitin-like0.6288Inherited
Growth factor receptor domain0.801Inherited


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

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SCOP termFDR (all)Annotation (direct or inherited)
Notch domain0Direct
beta-glycanases0Direct
Rel/Dorsal transcription factors, DNA-binding domain0Direct
DEATH domain, DD0.0004404Direct
C1 set domains (antibody constant domain-like)0.0005784Direct
Ras-binding domain, RBD0.0006133Direct
NF-kappa-B/REL/DORSAL transcription factors, C-terminal domain0.0006133Direct
VWC domain0.002689Inherited
MHC antigen-recognition domain0.01473Inherited
TNF receptor-like0.08727Inherited
V set domains (antibody variable domain-like)0.1898Inherited
ABC transporter transmembrane region0.2687Inherited
Arylsulfatase0.5559Inherited
ABC transporter ATPase domain-like0.7884Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Notch domain0Direct
Tricorn protease domain 20Direct
Saposin0Direct
DEATH domain0.0002403Direct
RCC1/BLIP-II0.0006807Direct
4-helical cytokines0.009569Inherited
MHC antigen-recognition domain0.01382Inherited
TNF receptor-like0.01653Inherited
Protein kinase-like (PK-like)0.1387Inherited
Snake toxin-like0.1457Inherited
Immunoglobulin0.3532Inherited
ABC transporter transmembrane region0.4069Inherited
Ubiquitin-like0.5882Inherited
Glucocorticoid receptor-like (DNA-binding domain)0.6415Inherited
Growth factor receptor domain0.7672Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
55550,55550
  • 55550 - SH2 domain
  • 55550 - SH2 domain
  • 0Direct
    57196,90193
  • 57196 - EGF/Laminin
  • 90193 - Notch domain
  • 0Direct
    49417,81296
  • 49417 - p53-like transcription factors
  • 81296 - E set domains
  • 0Direct
    54452,48726
  • 54452 - MHC antigen-recognition domain
  • 48726 - Immunoglobulin
  • 0.01382Inherited
    53300,53300
  • 53300 - vWA-like
  • 53300 - vWA-like
  • 0.02598Inherited
    57196,57184
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 0.3875Inherited
    90123,52540
  • 90123 - ABC transporter transmembrane region
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.4069Inherited
    57184,57184
  • 57184 - Growth factor receptor domain
  • 57184 - Growth factor receptor domain
  • 0.434Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    57196,57196,90193
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 90193 - Notch domain
  • 0Direct
    57196,57196,57184
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 0.001617Inherited
    57184,57184,57196
  • 57184 - Growth factor receptor domain
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 0.008573Inherited
    57196,57184,57184
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 57184 - Growth factor receptor domain
  • 0.5485Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
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