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Phenotypic Abnormality (PA): Abnormality of calvarial morphology

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Root: HP Hierarchy (human phenotype with 3 sub-ontologies PA, MI, ON)

Shortest distance to current term (+ for parents, - for children) HP term [HP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + + 5:   Abnormality of the skeletal system [HP:0000924] <7>(87|94) (95|55|32)
+ + + + + 5:   Phenotypic abnormality [HP:0000118] <25>
+ + + + 4:   Abnormality of head or neck [HP:0000152] <2>(84|104) (94|53|33)
+ + + + 4:   Abnormality of skeletal morphology [HP:0011842] <19>(82|83) (88|48|29)
+ + + 3:   Abnormal axial skeleton morphology [HP:0009121] <6>(46|57) (52|26|22)
+ + + 3:   Abnormality of the head [HP:0000234] <6>(83|101) (93|52|33)
+ + 2:   Abnormal skull morphology [HP:0000929] <14>(26|36) (29|17|16)
+ 1:   Abnormality of the calvaria [HP:0002683] <7>(8|15) (9|6|6)
0:   Abnormality of calvarial morphology [HP:0002648] <18>(3|9) (4|3|6)
- 1:   Craniosynostosis [HP:0001363] <5>(0|0) (0|0|0)
- 1:   Abnormal parietal bone morphology [HP:0002696] <3>(0|0) (0|0|0)
- 1:   Abnormal shape of the frontal region [HP:0011218] <2>(1|0) (1|0|0)
- 1:   Abnormal shape of the occiput [HP:0011217] <2>(1|1) (1|0|0)
- 1:   Brachycephaly [HP:0000248] <2>(0|0) (0|0|0)
- 1:   Plagiocephaly [HP:0001357] <2>(0|0) (0|0|0)
- 1:   Turricephaly [HP:0000262] <2>(0|0) (0|0|0)
- 1:   Cranial asymmetry [HP:0000267] <1>(0|1) (0|0|0)
- 1:   Dolichocephaly [HP:0000268] <1>(0|1) (0|0|2)
- 1:   Acrania [HP:0030716](0|0) (0|0|0)
- 1:   Biparietal narrowing [HP:0004422](0|1) (0|0|0)
- 1:   Broad skull [HP:0002682](0|0) (0|0|0)
- 1:   Calvarial skull defect [HP:0001362](0|0) (0|0|0)
- 1:   Cloverleaf skull [HP:0002676](0|1) (1|1|1)
- 1:   Obliteration of the calvarial diploe [HP:0030312](0|0) (0|0|0)
- 1:   Platybasia [HP:0002691](0|0) (0|0|0)
- 1:   Skull asymmetry [HP:0002678](0|0) (0|0|0)
- 1:   Trigonocephaly [HP:0000243](0|0) (0|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
Notch domain0Direct
HLH, helix-loop-helix DNA-binding domain0.2847Inherited
RuvA domain 2-like0.6574Inherited


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

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SCOP termFDR (all)Annotation (direct or inherited)
Notch domain0Direct
Protein serine/threonine phosphatase0Direct
Histone deacetylase, HDAC0Direct
PHD domain0.0005766Direct
Erythroid transcription factor GATA-10.0008893Direct
HLH, helix-loop-helix DNA-binding domain0.244Inherited
I set domains0.3953Inherited
G proteins0.4422Inherited
RecA protein-like (ATPase-domain)0.5404Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Notch domain0Direct
HLH, helix-loop-helix DNA-binding domain0.2473Inherited
RuvA domain 2-like0.6179Inherited
Immunoglobulin0.7983Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
57196,90193
  • 57196 - EGF/Laminin
  • 90193 - Notch domain
  • 0Direct
    57196,57184
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 0.0005798Direct
    48726,48726
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 0.3888Inherited

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    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    57196,57196,90193
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 90193 - Notch domain
  • 0Direct
    57184,57196,57184
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 0Direct
    57196,57196,57184
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 0.0004289Direct
    57196,57184,57184
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 57184 - Growth factor receptor domain
  • 0.0008947Direct
    57184,57196,57196
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.07529Inherited
    48726,48726,48726
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 0.2371Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
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