SUPERFAMILY 1.75 HMM library and genome assignments server

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Phenotypic Abnormality (PA): Abnormal blood glucose concentration

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Root: HP Hierarchy (human phenotype with 3 sub-ontologies PA, MI, ON)

Shortest distance to current term (+ for parents, - for children) HP term [HP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + 4:   Phenotypic abnormality [HP:0000118] <25>
+ + + 3:   Abnormality of metabolism/homeostasis [HP:0001939] <16>(76|83) (79|38|16)
+ + 2:   Abnormal homeostasis [HP:0012337] <8>(42|43) (42|21|8)
+ 1:   Abnormal glucose homeostasis [HP:0011014] <7>(10|11) (11|7|4)
0:   Abnormal blood glucose concentration [HP:0011015] <2>(7|7) (7|3|1)
- 1:   Hypoglycemia [HP:0001943] <7>(7|7) (7|3|1)
- 1:   Hyperglycemia [HP:0003074] <1>(0|0) (0|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
Acyl-CoA dehydrogenase C-terminal domain-like0.000009149Direct
Acyl-CoA dehydrogenase NM domain-like0.000009149Direct
Rudiment single hybrid motif0.0001836Direct
4Fe-4S ferredoxins0.0001836Direct
Insulin-like0.0001836Direct
Thiolase-like0.0007137Direct
Single hybrid motif0.000796Direct


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Family

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SCOP termFDR (all)Annotation (direct or inherited)
Medium chain acyl-CoA dehydrogenase, NM (N-terminal and middle) domains0.0000006898Direct
Medium chain acyl-CoA dehydrogenase-like, C-terminal domain0.0000006898Direct
BC C-terminal domain-like0.0001077Direct
Insulin-like0.0001077Direct
Biotinyl/lipoyl-carrier proteins and domains0.0004964Direct
BC ATP-binding domain-like0.001072Inherited
BC N-terminal domain-like0.001072Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Acyl-CoA dehydrogenase NM domain-like0.000004034Direct
Acyl-CoA dehydrogenase C-terminal domain-like0.000004034Direct
Insulin-like0.0000904Direct
Rudiment single hybrid motif0.0000904Direct
4Fe-4S ferredoxins0.0000904Direct
Thiolase-like0.0003784Direct
Single hybrid motif0.0004263Direct

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
56645,47203
  • 56645 - Acyl-CoA dehydrogenase NM domain-like
  • 47203 - Acyl-CoA dehydrogenase C-terminal domain-like
  • 0.000004034Direct
    56059,51246
  • 56059 - Glutathione synthetase ATP-binding domain-like
  • 51246 - Rudiment single hybrid motif
  • 0.0000904Direct
    53901,53901
  • 53901 - Thiolase-like
  • 53901 - Thiolase-like
  • 0.0003784Direct

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    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    52440,56059,51246
  • 52440 - PreATP-grasp domain
  • 56059 - Glutathione synthetase ATP-binding domain-like
  • 51246 - Rudiment single hybrid motif
  • 0.0000904Direct


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
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