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Phenotypic Abnormality (PA): Abnormality of the gastrointestinal tract

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Root: HP Hierarchy (human phenotype with 3 sub-ontologies PA, MI, ON)

Shortest distance to current term (+ for parents, - for children) HP term [HP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + 2:   Phenotypic abnormality [HP:0000118] <25>
+ 1:   Abnormality of the digestive system [HP:0025031] <6>(67|77) (77|47|25)
0:   Abnormality of the gastrointestinal tract [HP:0011024] <3>(24|27) (28|14|4)
- 1:   Neoplasm of the gastrointestinal tract [HP:0007378] <16>(6|5) (6|4|0)
- 1:   Functional abnormality of the gastrointestinal tract [HP:0012719] <11>(10|11) (14|2|0)
- 1:   Morphological abnormality of the gastrointestinal tract [HP:0012718] <8>(13|19) (17|9|4)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
SAND domain-like0Direct
Fibrinogen coiled-coil and central regions0Direct
Multidrug efflux transporter AcrB transmembrane domain0Direct
Zn-finger domain of Sec23/240Direct
beta-sandwich domain of Sec23/240.001566Inherited
CalX-like0.02226Inherited
Immunoglobulin0.04812Inherited
DNA repair protein MutS, domain III0.04952Inherited
Integrin domains0.08566Inherited
BRCT domain0.1229Inherited
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase0.1609Inherited
Actin-like ATPase domain0.1766Inherited
SH3-domain0.2107Inherited
Protein kinase-like (PK-like)0.2177Inherited
RNI-like0.2192Inherited
Ribosomal protein S5 domain 2-like0.2209Inherited
Snake toxin-like0.2837Inherited
DEATH domain0.5346Inherited
Ran binding protein zinc finger-like0.5373Inherited
SET domain0.7328Inherited
Cadherin-like0.7513Inherited
L domain-like0.92Inherited
alpha/beta-Hydrolases0.9347Inherited
Intermediate filament protein, coiled coil region0.9516Inherited


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Family

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SCOP termFDR (all)Annotation (direct or inherited)
P4 origin-binding domain-like0Direct
Fibrinogen coiled-coil and central regions0Direct
Zn-finger domain of Sec23/240Direct
Multidrug efflux transporter AcrB transmembrane domain0Direct
DNA polymerase I0Direct
DnaQ-like 3'-5' exonuclease0.006528Inherited
C1 set domains (antibody constant domain-like)0.01358Inherited
DNA gyrase/MutL, second domain0.01614Inherited
CalX-beta domain0.01614Inherited
DNA gyrase/MutL, N-terminal domain0.01614Inherited
Transforming growth factor (TGF)-beta0.0236Inherited
DNA repair protein MutS, domain III0.03837Inherited
Rel/Dorsal transcription factors, DNA-binding domain0.03837Inherited
Actin/HSP700.04548Inherited
RecA protein-like (ATPase-domain)0.06784Inherited
Integrin domains0.06784Inherited
SNARE fusion complex0.09887Inherited
Laminin G-like module0.1467Inherited
KRAB domain (Kruppel-associated box)0.1745Inherited
Laminin-type module0.1774Inherited
Extended AAA-ATPase domain0.1887Inherited
28-residue LRR0.3991Inherited
Ran binding protein zinc finger-like0.4971Inherited
Histone lysine methyltransferases0.6489Inherited
Cadherin0.7485Inherited
Ngr ectodomain-like0.8445Inherited
Intermediate filament protein, coiled coil region0.9444Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
SAND domain-like0Direct
Fibrinogen coiled-coil and central regions0Direct
Multidrug efflux transporter AcrB transmembrane domain0Direct
Zn-finger domain of Sec23/240Direct
beta-sandwich domain of Sec23/240.0008586Direct
DNA/RNA polymerases0.002313Inherited
CalX-like0.0153Inherited
Immunoglobulin0.03526Inherited
DNA repair protein MutS, domain III0.03644Inherited
Integrin domains0.0664Inherited
SNARE fusion complex0.09484Inherited
BRCT domain0.09822Inherited
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase0.1319Inherited
Actin-like ATPase domain0.1458Inherited
KRAB domain (Kruppel-associated box)0.1686Inherited
SH3-domain0.1772Inherited
Protein kinase-like (PK-like)0.1835Inherited
RNI-like0.1849Inherited
Ribosomal protein S5 domain 2-like0.1865Inherited
Snake toxin-like0.245Inherited
4-helical cytokines0.245Inherited
DEATH domain0.4905Inherited
Ran binding protein zinc finger-like0.4933Inherited
SET domain0.6949Inherited
Cadherin-like0.714Inherited
L domain-like0.8923Inherited
alpha/beta-Hydrolases0.9079Inherited
Intermediate filament protein, coiled coil region0.9263Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
57889,48350
  • 57889 - Cysteine-rich domain
  • 48350 - GTPase activation domain, GAP
  • 0Direct
    57196,90193
  • 57196 - EGF/Laminin
  • 90193 - Notch domain
  • 0Direct
    82919,53300
  • 82919 - Zn-finger domain of Sec23/24
  • 53300 - vWA-like
  • 0Direct
    103473,100895
  • 103473 - MFS general substrate transporter
  • 100895 - Kazal-type serine protease inhibitors
  • 0Direct
    53098,56672
  • 53098 - Ribonuclease H-like
  • 56672 - DNA/RNA polymerases
  • 0Direct
    57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.01481Inherited
    55874,54211
  • 55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
  • 54211 - Ribosomal protein S5 domain 2-like
  • 0.0153Inherited
    48334,52540
  • 48334 - DNA repair protein MutS, domain III
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.03644Inherited
    49417,81296
  • 49417 - p53-like transcription factors
  • 81296 - E set domains
  • 0.03644Inherited
    50249,50249
  • 50249 - Nucleic acid-binding proteins
  • 50249 - Nucleic acid-binding proteins
  • 0.03644Inherited
    49899,49899
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.06986Inherited
    53067,53067
  • 53067 - Actin-like ATPase domain
  • 53067 - Actin-like ATPase domain
  • 0.1064Inherited
    57903,57903
  • 57903 - FYVE/PHD zinc finger
  • 57903 - FYVE/PHD zinc finger
  • 0.2121Inherited
    49313,49313
  • 49313 - Cadherin-like
  • 49313 - Cadherin-like
  • 0.7328Inherited

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    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    57184,57196,57184
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 0Direct
    57196,57196,90193
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 90193 - Notch domain
  • 0Direct
    57196,57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.1752Inherited
    49313,49313,49313
  • 49313 - Cadherin-like
  • 49313 - Cadherin-like
  • 49313 - Cadherin-like
  • 0.7328Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
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