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Phenotypic Abnormality (PA): Abnormality of the gastrointestinal tract

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Root: HP Hierarchy (human phenotype with 3 sub-ontologies PA, MI, ON)

Shortest distance to current term (+ for parents, - for children) HP term [HP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + 2:   Phenotypic abnormality [HP:0000118] <25>
+ 1:   Abnormality of the digestive system [HP:0025031] <6>(59|66) (66|38|20)
0:   Abnormality of the gastrointestinal tract [HP:0011024] <3>(18|22) (23|10|4)
- 1:   Neoplasm of the gastrointestinal tract [HP:0007378] <16>(6|6) (6|4|1)
- 1:   Functional abnormality of the gastrointestinal tract [HP:0012719] <11>(7|8) (10|2|0)
- 1:   Morphological abnormality of the gastrointestinal tract [HP:0012718] <8>(11|15) (15|6|4)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
Zn-finger domain of Sec23/240Direct
SAND domain-like0Direct
Fibrinogen coiled-coil and central regions0Direct
DNA/RNA polymerases0.003161Inherited
CalX-like0.01946Inherited
DNA repair protein MutS, domain III0.04488Inherited
Integrin domains0.08376Inherited
BRCT domain0.1206Inherited
Ribosomal protein S5 domain 2-like0.129Inherited
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase0.1458Inherited
Actin-like ATPase domain0.2165Inherited
Snake toxin-like0.2711Inherited
Protein kinase-like (PK-like)0.2944Inherited
RNI-like0.4058Inherited
Ran binding protein zinc finger-like0.6416Inherited
DEATH domain0.6515Inherited
alpha/beta-Hydrolases0.7447Inherited
L domain-like0.8042Inherited


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Family

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SCOP termFDR (all)Annotation (direct or inherited)
DnaQ-like 3'-5' exonuclease0Direct
Zn-finger domain of Sec23/240Direct
Fibrinogen coiled-coil and central regions0Direct
P4 origin-binding domain-like0Direct
Multidrug efflux transporter AcrB transmembrane domain0Direct
DNA polymerase I0Direct
BCR-homology GTPase activation domain (BH-domain)0.004722Inherited
DNA gyrase/MutL, second domain0.01411Inherited
CalX-beta domain0.01411Inherited
DNA gyrase/MutL, N-terminal domain0.01411Inherited
DNA repair protein MutS, domain III0.03448Inherited
Rel/Dorsal transcription factors, DNA-binding domain0.03448Inherited
RecA protein-like (ATPase-domain)0.06431Inherited
Integrin domains0.06431Inherited
Actin/HSP700.06431Inherited
SNARE fusion complex0.09165Inherited
Laminin-type module0.1702Inherited
Extended AAA-ATPase domain0.1786Inherited
Protein kinases, catalytic subunit0.2631Inherited
Ran binding protein zinc finger-like0.6015Inherited
Histone lysine methyltransferases0.6375Inherited
Ngr ectodomain-like0.7463Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Fibrinogen coiled-coil and central regions0Direct
Zn-finger domain of Sec23/240Direct
SAND domain-like0Direct
beta-sandwich domain of Sec23/240.0006774Direct
DNA/RNA polymerases0.001895Inherited
CalX-like0.01339Inherited
DNA repair protein MutS, domain III0.03311Inherited
Integrin domains0.06539Inherited
SNARE fusion complex0.08708Inherited
BRCT domain0.0968Inherited
Ribosomal protein S5 domain 2-like0.1043Inherited
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase0.1193Inherited
Actin-like ATPase domain0.1832Inherited
E set domains0.1992Inherited
Snake toxin-like0.2345Inherited
Protein kinase-like (PK-like)0.2567Inherited
SH3-domain0.2838Inherited
RNI-like0.3641Inherited
SET domain0.5766Inherited
Ran binding protein zinc finger-like0.6016Inherited
DEATH domain0.612Inherited
alpha/beta-Hydrolases0.7084Inherited
L domain-like0.7706Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
82919,53300
  • 82919 - Zn-finger domain of Sec23/24
  • 53300 - vWA-like
  • 0Direct
    57196,90193
  • 57196 - EGF/Laminin
  • 90193 - Notch domain
  • 0Direct
    53098,56672
  • 53098 - Ribonuclease H-like
  • 56672 - DNA/RNA polymerases
  • 0Direct
    57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.01023Inherited
    55874,54211
  • 55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
  • 54211 - Ribosomal protein S5 domain 2-like
  • 0.01339Inherited
    49417,81296
  • 49417 - p53-like transcription factors
  • 81296 - E set domains
  • 0.03311Inherited
    50249,50249
  • 50249 - Nucleic acid-binding proteins
  • 50249 - Nucleic acid-binding proteins
  • 0.03311Inherited
    48334,52540
  • 48334 - DNA repair protein MutS, domain III
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.03311Inherited
    53067,53067
  • 53067 - Actin-like ATPase domain
  • 53067 - Actin-like ATPase domain
  • 0.1389Inherited
    57903,57903
  • 57903 - FYVE/PHD zinc finger
  • 57903 - FYVE/PHD zinc finger
  • 0.2099Inherited

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    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    57196,57196,90193
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 90193 - Notch domain
  • 0Direct
    57184,57196,57184
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 0Direct
    57196,57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.1528Inherited
    48726,48726,48726
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 0.3168Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
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