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Phenotypic Abnormality (PA): Abnormal digit morphology

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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Root: HP Hierarchy (human phenotype with 3 sub-ontologies PA, MI, ON)

Shortest distance to current term (+ for parents, - for children) HP term [HP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + 4:   Phenotypic abnormality [HP:0000118] <25>
+ + + 3:   Abnormality of limbs [HP:0040064] <8>(55|63) (58|31|22)
+ + + 3:   Abnormality of skeletal morphology [HP:0011842] <19>(82|83) (88|48|29)
+ + + 3:   Abnormality of the skeletal system [HP:0000924] <7>(87|94) (95|55|32)
+ + 2:   Abnormal appendicular skeleton morphology [HP:0011844] <4>(33|39) (37|23|21)
+ + 2:   Abnormality of limb bone [HP:0040068] <1>(25|27) (27|18|18)
+ 1:   Abnormality of limb bone morphology [HP:0002813] <13>(25|27) (27|18|18)
0:   Abnormal digit morphology [HP:0011297] <10>(18|20) (18|16|16)
- 1:   Abnormality of toe [HP:0001780] <27>(8|7) (8|4|2)
- 1:   Abnormality of finger [HP:0001167] <24>(11|16) (13|12|10)
- 1:   Polydactyly [HP:0010442] <6>(3|1) (3|2|0)
- 1:   Broad phalanx [HP:0006009] <3>(0|0) (0|0|0)
- 1:   Short digit [HP:0011927] <3>(3|6) (4|4|4)
- 1:   Syndactyly [HP:0001159] <3>(1|1) (1|1|1)
- 1:   Clinodactyly [HP:0030084] <2>(0|2) (1|0|0)
- 1:   Clubbing [HP:0001217] <2>(0|1) (0|0|0)
- 1:   Macrodactyly [HP:0004099] <2>(0|0) (0|0|0)
- 1:   Oligodactyly [HP:0012165] <2>(0|0) (0|0|0)


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
RuvA domain 2-like0Direct
BRK domain-like0Direct
TB module/8-cys domain0Direct
Hect, E3 ligase catalytic domain0.0004948Direct
Restriction endonuclease-like0.02492Inherited
Insulin-like0.02492Inherited
ARID-like0.02769Inherited
WD40 repeat-like0.05736Inherited
GroEL equatorial domain-like0.06461Inherited
Tudor/PWWP/MBT0.06622Inherited
HLH, helix-loop-helix DNA-binding domain0.1278Inherited
N-terminal nucleophile aminohydrolases (Ntn hydrolases)0.1749Inherited
Cystine-knot cytokines0.3925Inherited
Immunoglobulin0.4515Inherited
TPR-like0.6201Inherited
SCOP hierarchy in SUPERFAMILY0.7179Inherited
Class II aaRS and biotin synthetases0.8472Inherited
vWA-like0.9156Inherited


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

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SCOP termFDR (all)Annotation (direct or inherited)
TB module/8-cys domain0Direct
XPF/Rad1/Mus81 nuclease0Direct
BRK domain-like0Direct
Proteasome subunits0Direct
Exostosin0Direct
Hect, E3 ligase catalytic domain0.0002777Direct
Erythroid transcription factor GATA-10.0005467Direct
VWC domain0.007377Inherited
Insulin-like0.01756Inherited
Sema domain0.01811Inherited
ARID domain0.01972Inherited
Classic zinc finger, C2H20.04732Inherited
HLH, helix-loop-helix DNA-binding domain0.1049Inherited
RecA protein-like (ATPase-domain)0.1126Inherited
I set domains0.1419Inherited
Homeodomain0.2994Inherited
Transforming growth factor (TGF)-beta0.4018Inherited
Actin/HSP700.5576Inherited
Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain0.7179Inherited
Integrin A (or I) domain0.8107Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
TB module/8-cys domain0Direct
RuvA domain 2-like0Direct
BRK domain-like0Direct
Hect, E3 ligase catalytic domain0.0002582Direct
Insulin-like0.01747Inherited
Restriction endonuclease-like0.01747Inherited
Sema domain0.01802Inherited
ARID-like0.01959Inherited
WD40 repeat-like0.04334Inherited
GroEL equatorial domain-like0.04921Inherited
Tudor/PWWP/MBT0.05058Inherited
HLH, helix-loop-helix DNA-binding domain0.1032Inherited
N-terminal nucleophile aminohydrolases (Ntn hydrolases)0.1452Inherited
Cystine-knot cytokines0.3511Inherited
Immunoglobulin0.4092Inherited
TPR-like0.5791Inherited
Class II aaRS and biotin synthetases0.8153Inherited
vWA-like0.8878Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
57581,57196
  • 57581 - TB module/8-cys domain
  • 57196 - EGF/Laminin
  • 0Direct
    57184,57581
  • 57184 - Growth factor receptor domain
  • 57581 - TB module/8-cys domain
  • 0Direct
    57581,57184
  • 57581 - TB module/8-cys domain
  • 57184 - Growth factor receptor domain
  • 0Direct
    52980,47781
  • 52980 - Restriction endonuclease-like
  • 47781 - RuvA domain 2-like
  • 0Direct
    57196,57581
  • 57196 - EGF/Laminin
  • 57581 - TB module/8-cys domain
  • 0Direct
    57184,57184
  • 57184 - Growth factor receptor domain
  • 57184 - Growth factor receptor domain
  • 0.00007522Direct
    103575,48726
  • 103575 - Plexin repeat
  • 48726 - Immunoglobulin
  • 0.01747Inherited
    101912,103575
  • 101912 - Sema domain
  • 103575 - Plexin repeat
  • 0.01802Inherited
    57903,57903
  • 57903 - FYVE/PHD zinc finger
  • 57903 - FYVE/PHD zinc finger
  • 0.01959Inherited
    81296,81296
  • 81296 - E set domains
  • 81296 - E set domains
  • 0.04921Inherited
    53300,53300
  • 53300 - vWA-like
  • 53300 - vWA-like
  • 0.04921Inherited
    48726,48726
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 0.1501Inherited
    48452,48452
  • 48452 - TPR-like
  • 48452 - TPR-like
  • 0.1899Inherited
    57667,57667
  • 57667 - beta-beta-alpha zinc fingers
  • 57667 - beta-beta-alpha zinc fingers
  • 0.2054Inherited
    57196,57184
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 0.417Inherited
    50729,50729
  • 50729 - PH domain-like
  • 50729 - PH domain-like
  • 0.7002Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    57184,57184,57184
  • 57184 - Growth factor receptor domain
  • 57184 - Growth factor receptor domain
  • 57184 - Growth factor receptor domain
  • 0Direct
    57581,57196,57196
  • 57581 - TB module/8-cys domain
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0Direct
    57184,57184,57196
  • 57184 - Growth factor receptor domain
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 0Direct
    57196,57581,57196
  • 57196 - EGF/Laminin
  • 57581 - TB module/8-cys domain
  • 57196 - EGF/Laminin
  • 0Direct
    57184,57581,57196
  • 57184 - Growth factor receptor domain
  • 57581 - TB module/8-cys domain
  • 57196 - EGF/Laminin
  • 0Direct
    57196,57196,57581
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 57581 - TB module/8-cys domain
  • 0Direct
    57196,57581,57184
  • 57196 - EGF/Laminin
  • 57581 - TB module/8-cys domain
  • 57184 - Growth factor receptor domain
  • 0Direct
    57581,57196,57581
  • 57581 - TB module/8-cys domain
  • 57196 - EGF/Laminin
  • 57581 - TB module/8-cys domain
  • 0Direct
    57184,57184,57581
  • 57184 - Growth factor receptor domain
  • 57184 - Growth factor receptor domain
  • 57581 - TB module/8-cys domain
  • 0Direct
    57196,57184,57184
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 57184 - Growth factor receptor domain
  • 0Direct
    57184,57581,57184
  • 57184 - Growth factor receptor domain
  • 57581 - TB module/8-cys domain
  • 57184 - Growth factor receptor domain
  • 0Direct
    57581,57184,57581
  • 57581 - TB module/8-cys domain
  • 57184 - Growth factor receptor domain
  • 57581 - TB module/8-cys domain
  • 0Direct
    101912,103575,48726
  • 101912 - Sema domain
  • 103575 - Plexin repeat
  • 48726 - Immunoglobulin
  • 0.01747Inherited
    48726,48726,48726
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 0.03371Inherited
    81296,81296,81296
  • 81296 - E set domains
  • 81296 - E set domains
  • 81296 - E set domains
  • 0.04921Inherited
    57196,57196,57184
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 0.4526Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
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