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Phenotypic Abnormality (PA): Abnormality of joint mobility

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Root: HP Hierarchy (human phenotype with 3 sub-ontologies PA, MI, ON)

Shortest distance to current term (+ for parents, - for children) HP term [HP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + 3:   Phenotypic abnormality [HP:0000118] <25>
+ + 2:   Abnormality of the skeletal system [HP:0000924] <7>(88|98) (93|54|34)
+ 1:   Abnormality of skeletal physiology [HP:0011843] <8>(17|23) (17|15|15)
0:   Abnormality of joint mobility [HP:0011729] <6>(16|21) (16|15|15)
- 1:   Limitation of joint mobility [HP:0001376] <13>(2|2) (2|7|12)
- 1:   Flexion contracture [HP:0001371] <9>(8|10) (8|7|1)
- 1:   Joint hypermobility [HP:0001382] <8>(5|9) (5|3|1)
- 1:   Synostosis of joints [HP:0100240] <7>(3|1) (3|0|0)
- 1:   Joint laxity [HP:0001388] <2>(1|2) (1|1|0)
- 1:   Abnormality of hand joint mobility [HP:0006256] <1>(1|1) (1|1|0)


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
Ribonuclease PH domain 2-like0Direct
TB module/8-cys domain0Direct
Tropomyosin0.01986Inherited
Helical domain of Sec23/240.02079Inherited
C-terminal, gelsolin-like domain of Sec23/240.02079Inherited
ARID-like0.02238Inherited
Troponin coil-coiled subunits0.05482Inherited
Calponin-homology domain, CH-domain0.1117Inherited
vWA-like0.123Inherited
MIR domain0.1522Inherited
Ribosomal protein S5 domain 2-like0.1666Inherited
SET domain0.225Inherited
Bromodomain0.2612Inherited
Spectrin repeat0.3534Inherited
Histone-fold0.5539Inherited
Cystine-knot cytokines0.8597Inherited


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

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SCOP termFDR (all)Annotation (direct or inherited)
Ribonuclease PH domain 1-like0Direct
TB module/8-cys domain0Direct
Ribonuclease PH domain 2-like0Direct
Proteasome subunits0Direct
DNA gyrase/MutL, N-terminal domain0.004654Inherited
DNA gyrase/MutL, second domain0.004654Inherited
VWC domain0.005734Inherited
Tropomyosin0.01436Inherited
Helical domain of Sec23/240.01493Inherited
Trunk domain of Sec23/240.01493Inherited
beta-sandwich domain of Sec23/240.01493Inherited
C-terminal, gelsolin-like domain of Sec23/240.01493Inherited
Ras-binding domain, RBD0.01626Inherited
ARID domain0.01626Inherited
PHD domain0.08988Inherited
Calponin-homology domain, CH-domain0.09402Inherited
MIR domain0.1286Inherited
Integrin A (or I) domain0.1577Inherited
Bromodomain0.2202Inherited
Spectrin repeat0.3078Inherited
Rhodopsin-like1Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
TB module/8-cys domain0Direct
Ribonuclease PH domain 2-like0Direct
Tropomyosin0.01351Inherited
Helical domain of Sec23/240.0142Inherited
C-terminal, gelsolin-like domain of Sec23/240.0142Inherited
ARID-like0.01538Inherited
Troponin coil-coiled subunits0.04075Inherited
Calponin-homology domain, CH-domain0.08825Inherited
vWA-like0.09831Inherited
MIR domain0.1244Inherited
Ribosomal protein S5 domain 2-like0.1369Inherited
SET domain0.1903Inherited
Bromodomain0.2237Inherited
Spectrin repeat0.3116Inherited
Histone-fold0.5103Inherited
Cystine-knot cytokines0.8278Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
54211,55666
  • 54211 - Ribosomal protein S5 domain 2-like
  • 55666 - Ribonuclease PH domain 2-like
  • 0Direct
    57184,57581
  • 57184 - Growth factor receptor domain
  • 57581 - TB module/8-cys domain
  • 0Direct
    57581,57184
  • 57581 - TB module/8-cys domain
  • 57184 - Growth factor receptor domain
  • 0Direct
    57196,57581
  • 57196 - EGF/Laminin
  • 57581 - TB module/8-cys domain
  • 0Direct
    57581,57196
  • 57581 - TB module/8-cys domain
  • 57196 - EGF/Laminin
  • 0Direct
    55874,54211
  • 55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
  • 54211 - Ribosomal protein S5 domain 2-like
  • 0.004378Inherited
    57184,57184
  • 57184 - Growth factor receptor domain
  • 57184 - Growth factor receptor domain
  • 0.008792Inherited
    57184,57196
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 0.008792Inherited
    81811,82754
  • 81811 - Helical domain of Sec23/24
  • 82754 - C-terminal, gelsolin-like domain of Sec23/24
  • 0.0142Inherited
    49899,57196
  • 49899 - Concanavalin A-like lectins/glucanases
  • 57196 - EGF/Laminin
  • 0.03348Inherited
    53300,53300
  • 53300 - vWA-like
  • 53300 - vWA-like
  • 0.04075Inherited
    46966,46966
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 0.07065Inherited
    57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.08735Inherited
    48726,48726
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 0.1877Inherited
    50729,50729
  • 50729 - PH domain-like
  • 50729 - PH domain-like
  • 0.5103Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    57581,57196,57196
  • 57581 - TB module/8-cys domain
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0Direct
    57196,57581,57196
  • 57196 - EGF/Laminin
  • 57581 - TB module/8-cys domain
  • 57196 - EGF/Laminin
  • 0Direct
    57184,57581,57196
  • 57184 - Growth factor receptor domain
  • 57581 - TB module/8-cys domain
  • 57196 - EGF/Laminin
  • 0Direct
    57196,57196,57581
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 57581 - TB module/8-cys domain
  • 0Direct
    57581,57184,57581
  • 57581 - TB module/8-cys domain
  • 57184 - Growth factor receptor domain
  • 57581 - TB module/8-cys domain
  • 0Direct
    57196,57581,57184
  • 57196 - EGF/Laminin
  • 57581 - TB module/8-cys domain
  • 57184 - Growth factor receptor domain
  • 0Direct
    57581,57196,57581
  • 57581 - TB module/8-cys domain
  • 57196 - EGF/Laminin
  • 57581 - TB module/8-cys domain
  • 0Direct
    57184,57184,57184
  • 57184 - Growth factor receptor domain
  • 57184 - Growth factor receptor domain
  • 57184 - Growth factor receptor domain
  • 0Direct
    57184,57581,57184
  • 57184 - Growth factor receptor domain
  • 57581 - TB module/8-cys domain
  • 57184 - Growth factor receptor domain
  • 0Direct
    57184,57184,57581
  • 57184 - Growth factor receptor domain
  • 57184 - Growth factor receptor domain
  • 57581 - TB module/8-cys domain
  • 0Direct
    57184,57196,57184
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 0Direct
    57196,57184,57184
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 57184 - Growth factor receptor domain
  • 0.005389Inherited
    82895,82895,82895
  • 82895 - TSP-1 type 1 repeat
  • 82895 - TSP-1 type 1 repeat
  • 82895 - TSP-1 type 1 repeat
  • 0.03314Inherited
    46966,46966,46966
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 0.04993Inherited
    48726,48726,48726
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 0.05448Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
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