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Phenotypic Abnormality (PA): Abnormal reproductive system morphology

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Root: HP Hierarchy (human phenotype with 3 sub-ontologies PA, MI, ON)

Shortest distance to current term (+ for parents, - for children) HP term [HP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + 3:   Phenotypic abnormality [HP:0000118] <25>
+ + 2:   Abnormality of the genitourinary system [HP:0000119] <5>(72|74) (80|28|7)
+ 1:   Abnormality of the genital system [HP:0000078] <3>(33|36) (37|10|1)
0:   Abnormal reproductive system morphology [HP:0012243] <10>(26|28) (28|4|0)
- 1:   Abnormal internal genitalia [HP:0000812] <9>(16|17) (16|2|0)
- 1:   Abnormal external genitalia [HP:0000811] <7>(14|13) (16|1|0)
- 1:   Abnormality of the female genitalia [HP:0010460] <2>(17|18) (18|2|0)
- 1:   Abnormality of the male genitalia [HP:0010461] <2>(13|13) (16|1|0)
- 1:   Abnormal germ cell morphology [HP:0012862] <1>(0|0) (0|0|0)
- 1:   Abnormal meiosis [HP:0031515] <1>(0|0) (0|0|0)
- 1:   Abnormal sex determination [HP:0012244] <1>(0|0) (0|0|0)
- 1:   Genital tract atresia [HP:0001827] <1>(0|0) (0|0|0)
- 1:   Anteriorly displaced genitalia [HP:0003252](0|0) (0|0|0)
- 1:   Genital ulcers [HP:0003249](0|0) (0|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
Zn-finger domain of Sec23/240Direct
Smc hinge domain0Direct
BRK domain-like0Direct
DNA repair protein MutS, domain III0Direct
Fibrinogen coiled-coil and central regions0Direct
Isocitrate/Isopropylmalate dehydrogenase-like0Direct
SET domain0.0006352Direct
Bromodomain0.001504Inherited
RING/U-box0.01252Inherited
CalX-like0.01312Inherited
BRCT domain0.01789Inherited
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase0.03465Inherited
NagB/RpiA/CoA transferase-like0.07674Inherited
GroEL equatorial domain-like0.08414Inherited
Fibrinogen C-terminal domain-like0.2378Inherited
Glucocorticoid receptor-like (DNA-binding domain)0.2502Inherited
Family A G protein-coupled receptor-like0.3658Inherited
Ribosomal protein S5 domain 2-like0.468Inherited
Nuclear receptor ligand-binding domain0.4717Inherited
Ribonuclease H-like0.5022Inherited
ARID-like0.6895Inherited
Cytochrome P4500.7432Inherited
Trypsin-like serine proteases0.7571Inherited
"Winged helix" DNA-binding domain0.8623Inherited
DEATH domain0.9543Inherited
WD40 repeat-like0.9847Inherited


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

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SCOP termFDR (all)Annotation (direct or inherited)
Dimeric isocitrate & isopropylmalate dehydrogenases0Direct
DNA repair protein MutS, domain III0Direct
DIX domain0Direct
BRK domain-like0Direct
Zn-finger domain of Sec23/240Direct
Smc hinge domain0Direct
Fibrinogen coiled-coil and central regions0Direct
IF2B-like0Direct
Histone lysine methyltransferases0.0006889Direct
Bromodomain0.0009971Direct
RecA protein-like (ATPase-domain)0.00188Inherited
RING finger domain, C3HC40.003735Inherited
Tandem AAA-ATPase domain0.004963Inherited
DNA gyrase/MutL, second domain0.009323Inherited
CalX-beta domain0.009323Inherited
DNA gyrase/MutL, N-terminal domain0.009323Inherited
Extracellular domain of cell surface receptors0.1262Inherited
MIR domain0.1262Inherited
Fibrinogen C-terminal domain-like0.2121Inherited
ABC transporter ATPase domain-like0.2229Inherited
PHD domain0.321Inherited
Rhodopsin-like0.3669Inherited
Nuclear receptor ligand-binding domain0.4479Inherited
Ngr ectodomain-like0.4744Inherited
Nuclear receptor0.4788Inherited
Extended AAA-ATPase domain0.5467Inherited
ARID domain0.6698Inherited
Eukaryotic proteases0.7105Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Fibrinogen coiled-coil and central regions0Direct
Isocitrate/Isopropylmalate dehydrogenase-like0Direct
Zn-finger domain of Sec23/240Direct
Smc hinge domain0Direct
DNA repair protein MutS, domain III0Direct
BRK domain-like0Direct
SET domain0.0003369Direct
Bromodomain0.0008479Direct
RING/U-box0.00834Inherited
CalX-like0.00873Inherited
BRCT domain0.01221Inherited
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase0.02504Inherited
NagB/RpiA/CoA transferase-like0.05936Inherited
GroEL equatorial domain-like0.06571Inherited
MIR domain0.121Inherited
Fibrinogen C-terminal domain-like0.2032Inherited
Glucocorticoid receptor-like (DNA-binding domain)0.2146Inherited
FYVE/PHD zinc finger0.2823Inherited
Family A G protein-coupled receptor-like0.325Inherited
Ribosomal protein S5 domain 2-like0.4258Inherited
Nuclear receptor ligand-binding domain0.4296Inherited
Ribonuclease H-like0.459Inherited
ARID-like0.6509Inherited
Cytochrome P4500.7068Inherited
Trypsin-like serine proteases0.7214Inherited
"Winged helix" DNA-binding domain0.8313Inherited
DEATH domain0.9293Inherited
WD40 repeat-like0.9631Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
52540,46785
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 46785 - "Winged helix" DNA-binding domain
  • 0Direct
    82919,53300
  • 82919 - Zn-finger domain of Sec23/24
  • 53300 - vWA-like
  • 0Direct
    48334,52540
  • 48334 - DNA repair protein MutS, domain III
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    55874,54211
  • 55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
  • 54211 - Ribosomal protein S5 domain 2-like
  • 0.00873Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
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