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Phenotypic Abnormality (PA): Abnormality of digestive system physiology

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Root: HP Hierarchy (human phenotype with 3 sub-ontologies PA, MI, ON)

Shortest distance to current term (+ for parents, - for children) HP term [HP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + 2:   Phenotypic abnormality [HP:0000118] <25>
+ 1:   Abnormality of the digestive system [HP:0025031] <6>(59|66) (66|38|20)
0:   Abnormality of digestive system physiology [HP:0025032] <5>(22|23) (26|11|0)
- 1:   Abdominal symptom [HP:0011458] <12>(13|14) (14|6|0)
- 1:   Functional abnormality of the gastrointestinal tract [HP:0012719] <11>(7|8) (10|2|0)
- 1:   Abnormal large intestine physiology [HP:0012700] <4>(0|0) (0|0|0)
- 1:   Abnormality of hepatobiliary system physiology [HP:0025155] <3>(2|2) (2|2|0)
- 1:   Dependency on intravenous nutrition [HP:0025156](0|0) (0|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
SAND domain-like0Direct
Tricorn protease domain 20Direct
BPTI-like0Direct
Fibrinogen coiled-coil and central regions0Direct
Plakin repeat0Direct
FAD/NAD-linked reductases, dimerisation (C-terminal) domain0Direct
ADC-like0Direct
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases0.0005544Direct
Adenine nucleotide alpha hydrolases-like0.01157Inherited
MHC antigen-recognition domain0.02109Inherited
ValRS/IleRS/LeuRS editing domain0.02335Inherited
Calcium-dependent phosphotriesterase0.08585Inherited
Acyl-CoA dehydrogenase NM domain-like0.1678Inherited
Acyl-CoA dehydrogenase C-terminal domain-like0.1678Inherited
Ran binding protein zinc finger-like0.3036Inherited
SpoIIaa-like0.3081Inherited
RNI-like0.314Inherited
DEATH domain0.5095Inherited
L domain-like0.5146Inherited
Integrin domains0.5617Inherited
Actin-like ATPase domain0.7952Inherited
Homeodomain-like0.8747Inherited


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Family

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SCOP termFDR (all)Annotation (direct or inherited)
Serum paraoxonase/arylesterase 1, PON10Direct
FAD/NAD-linked reductases, dimerisation (C-terminal) domain0Direct
Fibrinogen coiled-coil and central regions0Direct
P4 origin-binding domain-like0Direct
Small Kunitz-type inhibitors & BPTI-like toxins0Direct
Plakin repeat0Direct
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases0.0008374Direct
Histone lysine methyltransferases0.008544Inherited
Medium chain acyl-CoA dehydrogenase, NM (N-terminal and middle) domains0.01639Inherited
Medium chain acyl-CoA dehydrogenase-like, C-terminal domain0.01639Inherited
MHC antigen-recognition domain0.01639Inherited
ValRS/IleRS/LeuRS editing domain0.01784Inherited
DNA gyrase/MutL, second domain0.03592Inherited
DNA gyrase/MutL, N-terminal domain0.03592Inherited
SNARE fusion complex0.1714Inherited
Anti-sigma factor antagonist SpoIIaa0.1714Inherited
Actin/HSP700.2161Inherited
Ran binding protein zinc finger-like0.269Inherited
BC N-terminal domain-like0.417Inherited
BC ATP-binding domain-like0.417Inherited
Pyrin domain, PYD0.417Inherited
Integrin domains0.5254Inherited
Ngr ectodomain-like0.7146Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Fibrinogen coiled-coil and central regions0Direct
FAD/NAD-linked reductases, dimerisation (C-terminal) domain0Direct
BPTI-like0Direct
ADC-like0Direct
Plakin repeat0Direct
SAND domain-like0Direct
Tricorn protease domain 20Direct
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases0.00029Direct
Adenine nucleotide alpha hydrolases-like0.007652Inherited
MHC antigen-recognition domain0.0146Inherited
ValRS/IleRS/LeuRS editing domain0.01628Inherited
Calcium-dependent phosphotriesterase0.06721Inherited
SET domain0.08886Inherited
Acyl-CoA dehydrogenase NM domain-like0.139Inherited
Acyl-CoA dehydrogenase C-terminal domain-like0.139Inherited
SNARE fusion complex0.1615Inherited
beta-sandwich domain of Sec23/240.2137Inherited
Ran binding protein zinc finger-like0.2656Inherited
SpoIIaa-like0.27Inherited
RNI-like0.2755Inherited
DEATH domain0.4664Inherited
L domain-like0.4714Inherited
Integrin domains0.5189Inherited
Snake toxin-like0.5189Inherited
Actin-like ATPase domain0.7612Inherited
Homeodomain-like0.8445Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
55550,55550
  • 55550 - SH2 domain
  • 55550 - SH2 domain
  • 0Direct
    52374,47323
  • 52374 - Nucleotidylyl transferase
  • 47323 - Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
  • 0Direct
    75399,75399
  • 75399 - Plakin repeat
  • 75399 - Plakin repeat
  • 0Direct
    51905,55424
  • 51905 - FAD/NAD(P)-binding domain
  • 55424 - FAD/NAD-linked reductases, dimerisation (C-terminal) domain
  • 0Direct
    54452,48726
  • 54452 - MHC antigen-recognition domain
  • 48726 - Immunoglobulin
  • 0.0146Inherited
    50677,52374
  • 50677 - ValRS/IleRS/LeuRS editing domain
  • 52374 - Nucleotidylyl transferase
  • 0.01628Inherited
    55874,54211
  • 55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
  • 54211 - Ribosomal protein S5 domain 2-like
  • 0.03323Inherited
    56645,47203
  • 56645 - Acyl-CoA dehydrogenase NM domain-like
  • 47203 - Acyl-CoA dehydrogenase C-terminal domain-like
  • 0.139Inherited
    48371,48371
  • 48371 - ARM repeat
  • 48371 - ARM repeat
  • 0.249Inherited
    52440,56059
  • 52440 - PreATP-grasp domain
  • 56059 - Glutathione synthetase ATP-binding domain-like
  • 0.4124Inherited
    53067,53067
  • 53067 - Actin-like ATPase domain
  • 53067 - Actin-like ATPase domain
  • 0.6844Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
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