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Phenotypic Abnormality (PA): Abnormality of digestive system morphology

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Root: HP Hierarchy (human phenotype with 3 sub-ontologies PA, MI, ON)

Shortest distance to current term (+ for parents, - for children) HP term [HP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + 2:   Phenotypic abnormality [HP:0000118] <25>
+ 1:   Abnormality of the digestive system [HP:0025031] <6>(67|77) (77|47|25)
0:   Abnormality of digestive system morphology [HP:0025033] <2>(13|19) (17|9|4)
- 1:   Morphological abnormality of the gastrointestinal tract [HP:0012718] <8>(13|19) (17|9|4)
- 1:   Abnormal stool composition [HP:0031685] <2>(0|0) (0|0|0)


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
Zn-finger domain of Sec23/240Direct
CalX-like0.007713Inherited
DNA repair protein MutS, domain III0.0224Inherited
Protein kinase-like (PK-like)0.107Inherited
Ribosomal protein S5 domain 2-like0.1106Inherited
SH3-domain0.1125Inherited
Snake toxin-like0.1285Inherited
RNI-like0.1447Inherited
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase0.1677Inherited
DEATH domain0.3561Inherited
SET domain0.3855Inherited
Cadherin-like0.4839Inherited
alpha/beta-Hydrolases0.8946Inherited


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

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SCOP termFDR (all)Annotation (direct or inherited)
P4 origin-binding domain-like0Direct
Zn-finger domain of Sec23/240Direct
DNA gyrase/MutL, second domain0.005091Inherited
CalX-beta domain0.005091Inherited
DNA gyrase/MutL, N-terminal domain0.005091Inherited
C1 set domains (antibody constant domain-like)0.008371Inherited
DNA repair protein MutS, domain III0.01601Inherited
Transforming growth factor (TGF)-beta0.03217Inherited
Laminin G-like module0.04386Inherited
SNARE fusion complex0.04555Inherited
DnaQ-like 3'-5' exonuclease0.05201Inherited
DNA polymerase I0.05201Inherited
RecA protein-like (ATPase-domain)0.0827Inherited
KRAB domain (Kruppel-associated box)0.08612Inherited
Laminin-type module0.158Inherited
Extended AAA-ATPase domain0.1883Inherited
28-residue LRR0.3509Inherited
Histone lysine methyltransferases0.3509Inherited
Cadherin0.4938Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Zn-finger domain of Sec23/240Direct
CalX-like0.004866Inherited
DNA repair protein MutS, domain III0.01539Inherited
DNA/RNA polymerases0.02783Inherited
SNARE fusion complex0.0437Inherited
Multidrug efflux transporter AcrB transmembrane domain0.0515Inherited
KRAB domain (Kruppel-associated box)0.0832Inherited
Protein kinase-like (PK-like)0.08434Inherited
Ribosomal protein S5 domain 2-like0.08728Inherited
SH3-domain0.08898Inherited
Snake toxin-like0.1033Inherited
RNI-like0.1178Inherited
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase0.1379Inherited
DEATH domain0.3141Inherited
SET domain0.3423Inherited
Cadherin-like0.4402Inherited
alpha/beta-Hydrolases0.8649Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
57196,90193
  • 57196 - EGF/Laminin
  • 90193 - Notch domain
  • 0Direct
    82919,53300
  • 82919 - Zn-finger domain of Sec23/24
  • 53300 - vWA-like
  • 0Direct
    103473,100895
  • 103473 - MFS general substrate transporter
  • 100895 - Kazal-type serine protease inhibitors
  • 0Direct
    55874,54211
  • 55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
  • 54211 - Ribosomal protein S5 domain 2-like
  • 0.004866Inherited
    57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.006666Inherited
    48334,52540
  • 48334 - DNA repair protein MutS, domain III
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.01539Inherited
    49899,49899
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.01771Inherited
    57903,57903
  • 57903 - FYVE/PHD zinc finger
  • 57903 - FYVE/PHD zinc finger
  • 0.09414Inherited
    49313,49313
  • 49313 - Cadherin-like
  • 49313 - Cadherin-like
  • 0.4841Inherited

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    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    57184,57196,57184
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 0Direct
    57196,57196,90193
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 90193 - Notch domain
  • 0Direct
    57196,57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.188Inherited
    49313,49313,49313
  • 49313 - Cadherin-like
  • 49313 - Cadherin-like
  • 49313 - Cadherin-like
  • 0.4841Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
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