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Phenotypic Abnormality (PA): Abnormality of digestive system morphology

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Root: HP Hierarchy (human phenotype with 3 sub-ontologies PA, MI, ON)

Shortest distance to current term (+ for parents, - for children) HP term [HP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + 2:   Phenotypic abnormality [HP:0000118] <25>
+ 1:   Abnormality of the digestive system [HP:0025031] <6>(59|66) (66|38|20)
0:   Abnormality of digestive system morphology [HP:0025033] <2>(11|15) (15|6|4)
- 1:   Morphological abnormality of the gastrointestinal tract [HP:0012718] <8>(11|15) (15|6|4)
- 1:   Abnormal stool composition [HP:0031685] <2>(0|0) (0|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
Zn-finger domain of Sec23/240Direct
CalX-like0.006532Inherited
DNA repair protein MutS, domain III0.01979Inherited
DNA/RNA polymerases0.03674Inherited
Ribosomal protein S5 domain 2-like0.06354Inherited
Snake toxin-like0.1145Inherited
Protein kinase-like (PK-like)0.1582Inherited
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase0.1595Inherited
RNI-like0.2849Inherited
DEATH domain0.3505Inherited
alpha/beta-Hydrolases0.7296Inherited


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Family

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SCOP termFDR (all)Annotation (direct or inherited)
Zn-finger domain of Sec23/240Direct
P4 origin-binding domain-like0Direct
BCR-homology GTPase activation domain (BH-domain)0.0005918Direct
DNA gyrase/MutL, second domain0.004355Inherited
CalX-beta domain0.004355Inherited
DNA gyrase/MutL, N-terminal domain0.004355Inherited
DNA repair protein MutS, domain III0.01411Inherited
SNARE fusion complex0.04088Inherited
DnaQ-like 3'-5' exonuclease0.04901Inherited
DNA polymerase I0.04901Inherited
RecA protein-like (ATPase-domain)0.07789Inherited
Protein kinases, catalytic subunit0.1252Inherited
Laminin-type module0.1502Inherited
Extended AAA-ATPase domain0.177Inherited
Histone lysine methyltransferases0.3382Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Zn-finger domain of Sec23/240Direct
CalX-like0.004159Inherited
DNA repair protein MutS, domain III0.01362Inherited
DNA/RNA polymerases0.02666Inherited
SNARE fusion complex0.0395Inherited
Ribosomal protein S5 domain 2-like0.04835Inherited
Snake toxin-like0.09155Inherited
Protein kinase-like (PK-like)0.1301Inherited
SH3-domain0.1313Inherited
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase0.1314Inherited
SET domain0.2475Inherited
RNI-like0.2475Inherited
DEATH domain0.3101Inherited
E set domains0.4934Inherited
alpha/beta-Hydrolases0.6922Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
82919,53300
  • 82919 - Zn-finger domain of Sec23/24
  • 53300 - vWA-like
  • 0Direct
    57196,90193
  • 57196 - EGF/Laminin
  • 90193 - Notch domain
  • 0Direct
    55874,54211
  • 55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
  • 54211 - Ribosomal protein S5 domain 2-like
  • 0.004159Inherited
    57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.004413Inherited
    48334,52540
  • 48334 - DNA repair protein MutS, domain III
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.01362Inherited
    57903,57903
  • 57903 - FYVE/PHD zinc finger
  • 57903 - FYVE/PHD zinc finger
  • 0.09195Inherited

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    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    57196,57196,90193
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 90193 - Notch domain
  • 0Direct
    57184,57196,57184
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 0Direct
    57196,57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.1659Inherited
    48726,48726,48726
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 0.2609Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
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