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Phenotypic Abnormality (PA): Abnormality of the cerebral vasculature

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Root: HP Hierarchy (human phenotype with 3 sub-ontologies PA, MI, ON)

Shortest distance to current term (+ for parents, - for children) HP term [HP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + 4:   Abnormality of the nervous system [HP:0000707] <4>(140|161) (154|97|43)
+ + + 3:   Phenotypic abnormality [HP:0000118] <25>
+ + + 3:   Abnormality of nervous system morphology [HP:0012639] <5>(70|93) (79|45|15)
+ + 2:   Abnormality of the cardiovascular system [HP:0001626] <5>(58|73) (67|39|27)
+ + 2:   Morphological abnormality of the central nervous system [HP:0002011] <17>(62|82) (71|38|15)
+ 1:   Abnormality of brain morphology [HP:0012443] <13>(45|61) (53|29|13)
+ 1:   Abnormality of the vasculature [HP:0002597] <13>(32|47) (40|24|15)
0:   Abnormality of the cerebral vasculature [HP:0100659] <7>(8|11) (11|4|1)
- 1:   Abnormal cerebral artery morphology [HP:0009145] <9>(3|4) (5|2|0)
- 1:   Intracranial hemorrhage [HP:0002170] <6>(4|6) (5|1|1)
- 1:   Stroke [HP:0001297] <3>(2|2) (2|1|0)
- 1:   Abnormality of cerebral veins [HP:0012480] <2>(0|0) (0|0|0)
- 1:   Cerebral arteriovenous malformation [HP:0002408](0|0) (0|0|0)
- 1:   Cerebral vasculitis [HP:0005318](0|0) (0|0|0)
- 1:   Perivascular spaces [HP:0012520](0|0) (0|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
Fibrinogen coiled-coil and central regions0Direct
GLA-domain0.00003435Direct
Fibrinogen C-terminal domain-like0.000238Direct
Integrin domains0.01345Inherited
MHC antigen-recognition domain0.02268Inherited
Snake toxin-like0.04855Inherited
Actin-like ATPase domain0.06513Inherited
Complement control module/SCR domain0.1011Inherited


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Family

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SCOP termFDR (all)Annotation (direct or inherited)
Fibrinogen coiled-coil and central regions0Direct
GLA-domain0.00002655Direct
Fibrinogen C-terminal domain-like0.0001877Direct
Actin/HSP700.007357Inherited
Medium chain acyl-CoA dehydrogenase, NM (N-terminal and middle) domains0.01113Inherited
Integrin domains0.01113Inherited
Medium chain acyl-CoA dehydrogenase-like, C-terminal domain0.01113Inherited
Myosin rod fragments0.01588Inherited
MHC antigen-recognition domain0.0193Inherited
Complement control module/SCR domain0.09585Inherited
Transforming growth factor (TGF)-beta0.09712Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Fibrinogen coiled-coil and central regions0Direct
GLA-domain0.00001584Direct
Fibrinogen C-terminal domain-like0.0001194Direct
Integrin domains0.008966Inherited
Myosin rod fragments0.01288Inherited
MHC antigen-recognition domain0.01576Inherited
4-helical cytokines0.02486Inherited
Snake toxin-like0.03608Inherited
Actin-like ATPase domain0.04962Inherited
Complement control module/SCR domain0.08009Inherited
Cystine-knot cytokines0.08074Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
57630,57196
  • 57630 - GLA-domain
  • 57196 - EGF/Laminin
  • 0.0001758Direct
    54452,48726
  • 54452 - MHC antigen-recognition domain
  • 48726 - Immunoglobulin
  • 0.01576Inherited
    53067,53067
  • 53067 - Actin-like ATPase domain
  • 53067 - Actin-like ATPase domain
  • 0.02903Inherited
    57535,57535
  • 57535 - Complement control module/SCR domain
  • 57535 - Complement control module/SCR domain
  • 0.06487Inherited

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    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    57535,57535,57535
  • 57535 - Complement control module/SCR domain
  • 57535 - Complement control module/SCR domain
  • 57535 - Complement control module/SCR domain
  • 0.008637Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
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