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Phenotypic Abnormality (PA): Abnormal liver morphology

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Root: HP Hierarchy (human phenotype with 3 sub-ontologies PA, MI, ON)

Shortest distance to current term (+ for parents, - for children) HP term [HP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + 4:   Phenotypic abnormality [HP:0000118] <25>
+ + + 3:   Abnormality of the digestive system [HP:0025031] <6>(59|66) (66|38|20)
+ + 2:   Abnormality of the abdominal organs [HP:0002012] <6>(27|24) (31|12|2)
+ 1:   Abnormality of the liver [HP:0001392] <4>(15|11) (17|6|0)
0:   Abnormal liver morphology [HP:0410042] <25>(12|7) (13|4|0)
- 1:   Hepatitis [HP:0012115] <7>(0|0) (0|0|0)
- 1:   Abnormality of the hepatic vasculature [HP:0006707] <5>(0|0) (0|0|0)
- 1:   Elevated hepatic transaminase [HP:0002910] <4>(0|1) (0|0|0)
- 1:   Abnormal liver parenchyma morphology [HP:0030146] <3>(0|0) (0|0|0)
- 1:   Abnormal liver sonography [HP:0031140] <3>(0|0) (0|0|0)
- 1:   Cirrhosis [HP:0001394] <3>(0|0) (0|0|0)
- 1:   Hepatic fibrosis [HP:0001395] <3>(2|0) (3|1|0)
- 1:   Cystic liver disease [HP:0006706] <2>(1|0) (1|0|0)
- 1:   Hepatic necrosis [HP:0002605] <2>(0|0) (0|0|0)
- 1:   Abnormal hepatic glycogen storage [HP:0500030] <1>(0|0) (0|0|0)
- 1:   Abnormal hepatic iron concentration [HP:0040134] <1>(0|0) (0|0|0)
- 1:   Hepatomegaly [HP:0002240] <1>(1|2) (1|0|0)
- 1:   Storage in hepatocytes [HP:0031137] <1>(6|4) (6|2|0)
- 1:   Decreased carnitine level in liver [HP:0045061](0|0) (0|0|0)
- 1:   Degenerative liver disease [HP:0005237](0|0) (0|0|0)
- 1:   Depletion of mitochondrial DNA in liver [HP:0006581](0|0) (0|0|0)
- 1:   Ectopic liver [HP:0030722](0|0) (0|0|0)
- 1:   Hepatic agenesis [HP:0100839](0|0) (0|0|0)
- 1:   Hepatic amyloidosis [HP:0012280](0|0) (0|0|0)
- 1:   Hepatic calcification [HP:0006559](0|0) (0|0|0)
- 1:   Hepatic granulomatosis [HP:0011955](0|0) (0|0|0)
- 1:   Hepatopulmonary fusion [HP:0410259](0|0) (0|0|0)
- 1:   Hepatosplenomegaly [HP:0001433](0|0) (0|0|0)
- 1:   Liver abscess [HP:0100523](1|1) (1|0|0)
- 1:   Nodular regenerative hyperplasia of liver [HP:0011954](0|0) (0|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
(Trans)glycosidases0.0001986Direct
Globin-like0.0004569Direct
Acyl-CoA dehydrogenase NM domain-like0.006953Inherited
Acyl-CoA dehydrogenase C-terminal domain-like0.006953Inherited
Adenine nucleotide alpha hydrolases-like0.01657Inherited
GroEL equatorial domain-like0.02403Inherited
6-phosphogluconate dehydrogenase C-terminal domain-like0.07473Inherited
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases0.09233Inherited
Nucleotidylyl transferase0.1441Inherited
TPR-like0.2131Inherited
SH3-domain0.4475Inherited
WD40 repeat-like0.6539Inherited


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Family

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SCOP termFDR (all)Annotation (direct or inherited)
Proteasome subunits0Direct
Globins0.0002796Direct
Medium chain acyl-CoA dehydrogenase, NM (N-terminal and middle) domains0.007812Inherited
Medium chain acyl-CoA dehydrogenase-like, C-terminal domain0.007812Inherited
Class I aminoacyl-tRNA synthetases (RS), catalytic domain0.05468Inherited
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases0.1605Inherited
SH3-domain0.3912Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
(Trans)glycosidases0.00009868Direct
Globin-like0.0002377Direct
Glycosyl hydrolase domain0.0008822Direct
Acyl-CoA dehydrogenase NM domain-like0.004459Inherited
Acyl-CoA dehydrogenase C-terminal domain-like0.004459Inherited
Adenine nucleotide alpha hydrolases-like0.01122Inherited
GroEL equatorial domain-like0.01683Inherited
6-phosphogluconate dehydrogenase C-terminal domain-like0.0576Inherited
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases0.07271Inherited
Nucleotidylyl transferase0.1179Inherited
TPR-like0.1803Inherited
SH3-domain0.4051Inherited
WD40 repeat-like0.6143Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
51445,51011
  • 51445 - (Trans)glycosidases
  • 51011 - Glycosyl hydrolase domain
  • 0.0008822Direct
    56645,47203
  • 56645 - Acyl-CoA dehydrogenase NM domain-like
  • 47203 - Acyl-CoA dehydrogenase C-terminal domain-like
  • 0.004459Inherited
    52374,47323
  • 52374 - Nucleotidylyl transferase
  • 47323 - Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
  • 0.0576Inherited
    50978,50978
  • 50978 - WD40 repeat-like
  • 50978 - WD40 repeat-like
  • 0.1183Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
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