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Mammalian Phenotype (MP): renal/urinary system phenotype

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Root: MP Hierarchy (mammalian/mouse phenotype from MGI_4.41)

Shortest distance to current term (+ for parents, - for children) MP term [MP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ 1:   mammalian phenotype [MP:0000001] <29>
0:   renal/urinary system phenotype [MP:0005367] <2>(41|47) (46|26|11)
- 1:   abnormal renal/urinary system morphology [MP:0000516] <14>(31|36) (36|22|11)
- 1:   abnormal renal/urinary system physiology [MP:0005502] <6>(20|21) (25|10|1)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
Anaphylotoxins (complement system)0Direct
Nitric oxide (NO) synthase oxygenase domain0Direct
Growth factor receptor domain0.000002758Direct
Aquaporin-like0.00006007Direct
EGF/Laminin0.0001446Direct
(Trans)glycosidases0.0003209Direct
Families 57/38 glycoside transferase middle domain0.0007986Direct
Notch domain0.0007986Direct
MFS general substrate transporter0.0008077Direct
Phoshotransferase/anion transport protein0.001053Inherited
CBS-domain pair0.001128Inherited
Clc chloride channel0.001835Inherited
Ferredoxin reductase-like, C-terminal NADP-linked domain0.002114Inherited
Riboflavin synthase domain-like0.002114Inherited
Cystine-knot cytokines0.002352Inherited
Glycoside hydrolase/deacetylase0.002963Inherited
L-aspartase-like0.003911Inherited
Galactose mutarotase-like0.007031Inherited
Flavoproteins0.007031Inherited
Glucocorticoid receptor-like (DNA-binding domain)0.007078Inherited
FnI-like domain0.007778Inherited
CalX-like0.01345Inherited
Plexin repeat0.0312Inherited
Nuclear receptor ligand-binding domain0.03604Inherited
Toll/Interleukin receptor TIR domain0.03893Inherited
HCP-like0.04139Inherited
TNF receptor-like0.05376Inherited
C-type lectin-like0.05417Inherited
Integrin domains0.05709Inherited
L30e-like0.06215Inherited
Bcl-2 inhibitors of programmed cell death0.08602Inherited
Sema domain0.0916Inherited
Integrin alpha N-terminal domain0.0923Inherited
TPR-like0.169Inherited
Cyclin-like0.2563Inherited
ARM repeat0.2596Inherited
Cadherin-like0.4137Inherited
Metalloproteases ("zincins"), catalytic domain0.4455Inherited
Homeodomain-like0.5807Inherited
Nicotinic receptor ligand binding domain-like0.6712Inherited
Neurotransmitter-gated ion-channel transmembrane pore0.6712Inherited


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Family

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SCOP termFDR (all)Annotation (direct or inherited)
Anaphylotoxins (complement system)0Direct
Retinoblastoma tumor suppressor domains0Direct
Nitric oxide (NO) synthase oxygenase domain0Direct
Cytochrome p450 reductase N-terminal domain-like0Direct
Growth factor receptor domain0.000005989Direct
Aquaporin-like0.00003702Direct
Arylsulfatase0.0002832Direct
CBS-domain pair0.0003815Direct
alpha-mannosidase, domain 20.0005059Direct
Notch domain0.0005059Direct
NADPH-cytochrome p450 reductase FAD-binding domain-like0.0005059Direct
alpha-mannosidase0.0005059Direct
NADPH-cytochrome p450 reductase-like0.0005059Direct
VWC domain0.0007566Direct
Clc chloride channel0.001232Inherited
Noncollagenous (NC1) domain of collagen IV0.001999Inherited
alpha-mannosidase, C-terminal domain0.002635Inherited
Anion transport protein, cytoplasmic domain0.002728Inherited
EGF-type module0.002838Inherited
Transforming growth factor (TGF)-beta0.004747Inherited
Medium chain acyl-CoA dehydrogenase, NM (N-terminal and middle) domains0.004986Inherited
Medium chain acyl-CoA dehydrogenase-like, C-terminal domain0.004986Inherited
Platelet-derived growth factor-like0.009838Inherited
CalX-beta domain0.009838Inherited
Phoshoinositide 3-kinase (PI3K), catalytic domain0.01981Inherited
Nuclear receptor0.02203Inherited
Toll/Interleukin receptor TIR domain0.0247Inherited
Plexin repeat0.02521Inherited
Laminin-type module0.02668Inherited
Nuclear receptor ligand-binding domain0.02963Inherited
Tetratricopeptide repeat (TPR)0.04616Inherited
Integrin domains0.04678Inherited
TNF receptor-like0.04805Inherited
PLC-like (P variant)0.04829Inherited
Forkhead DNA-binding domain0.05579Inherited
Bcl-2 inhibitors of programmed cell death0.07008Inherited
Rhodopsin-like0.07062Inherited
Sema domain0.07739Inherited
Integrin alpha N-terminal domain0.1075Inherited
Short-chain cytokines0.1774Inherited
Fibroblast growth factors (FGF)0.2804Inherited
Cadherin0.3473Inherited
Leucine zipper domain0.463Inherited
I set domains0.5797Inherited
Nicotinic receptor ligand binding domain-like0.6524Inherited
Neurotransmitter-gated ion-channel transmembrane pore0.6524Inherited
Homeodomain0.7551Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Nitric oxide (NO) synthase oxygenase domain0Direct
Anaphylotoxins (complement system)0Direct
Growth factor receptor domain0.000001157Direct
Aquaporin-like0.00002837Direct
EGF/Laminin0.00007199Direct
(Trans)glycosidases0.0001662Direct
Families 57/38 glycoside transferase middle domain0.0004306Direct
Notch domain0.0004306Direct
MFS general substrate transporter0.0004356Direct
Phoshotransferase/anion transport protein0.0005764Direct
CBS-domain pair0.000619Direct
Clc chloride channel0.001038Inherited
Riboflavin synthase domain-like0.001205Inherited
Ferredoxin reductase-like, C-terminal NADP-linked domain0.001205Inherited
Cystine-knot cytokines0.001346Inherited
Glycoside hydrolase/deacetylase0.001718Inherited
L-aspartase-like0.002301Inherited
Galactose mutarotase-like0.004307Inherited
Flavoproteins0.004307Inherited
Glucocorticoid receptor-like (DNA-binding domain)0.004341Inherited
FnI-like domain0.004781Inherited
CalX-like0.008575Inherited
Acyl-CoA dehydrogenase C-terminal domain-like0.01467Inherited
Acyl-CoA dehydrogenase NM domain-like0.01467Inherited
Plexin repeat0.02131Inherited
Nuclear receptor ligand-binding domain0.02482Inherited
Toll/Interleukin receptor TIR domain0.02696Inherited
HCP-like0.02882Inherited
TNF receptor-like0.0382Inherited
C-type lectin-like0.03853Inherited
Integrin domains0.04089Inherited
L30e-like0.04491Inherited
Bcl-2 inhibitors of programmed cell death0.06398Inherited
Sema domain0.06862Inherited
Integrin alpha N-terminal domain0.06918Inherited
TPR-like0.1353Inherited
Family A G protein-coupled receptor-like0.1554Inherited
Cyclin-like0.2156Inherited
ARM repeat0.2186Inherited
Cadherin-like0.3669Inherited
Metalloproteases ("zincins"), catalytic domain0.3979Inherited
Cytokine0.4Inherited
Leucine zipper domain0.4345Inherited
Homeodomain-like0.5344Inherited
Neurotransmitter-gated ion-channel transmembrane pore0.6289Inherited
Nicotinic receptor ligand binding domain-like0.6289Inherited

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
49410,50242
  • 49410 - Alpha-macroglobulin receptor domain
  • 50242 - TIMP-like
  • 0Direct
    57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.0001676Direct
    88713,88688
  • 88713 - Glycoside hydrolase/deacetylase
  • 88688 - Families 57/38 glycoside transferase middle domain
  • 0.0004306Direct
    57196,90193
  • 57196 - EGF/Laminin
  • 90193 - Notch domain
  • 0.002301Inherited
    48452,81901
  • 48452 - TPR-like
  • 81901 - HCP-like
  • 0.002301Inherited
    57184,57196
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 0.003526Inherited
    57603,57603
  • 57603 - FnI-like domain
  • 57603 - FnI-like domain
  • 0.004307Inherited
    57184,57184
  • 57184 - Growth factor receptor domain
  • 57184 - Growth factor receptor domain
  • 0.004575Inherited
    57716,48508
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 48508 - Nuclear receptor ligand-binding domain
  • 0.00758Inherited
    57196,57184
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 0.009278Inherited
    56645,47203
  • 56645 - Acyl-CoA dehydrogenase NM domain-like
  • 47203 - Acyl-CoA dehydrogenase C-terminal domain-like
  • 0.01467Inherited
    52799,49562
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 0.01642Inherited
    69318,69179
  • 69318 - Integrin alpha N-terminal domain
  • 69179 - Integrin domains
  • 0.06713Inherited
    69179,69179
  • 69179 - Integrin domains
  • 69179 - Integrin domains
  • 0.06713Inherited
    101912,103575
  • 101912 - Sema domain
  • 103575 - Plexin repeat
  • 0.06862Inherited
    50044,55550
  • 50044 - SH3-domain
  • 55550 - SH2 domain
  • 0.07967Inherited
    56436,56436
  • 56436 - C-type lectin-like
  • 56436 - C-type lectin-like
  • 0.1156Inherited
    57586,57586
  • 57586 - TNF receptor-like
  • 57586 - TNF receptor-like
  • 0.1368Inherited
    51045,51045
  • 51045 - WW domain
  • 51045 - WW domain
  • 0.1651Inherited
    50156,50044
  • 50156 - PDZ domain-like
  • 50044 - SH3-domain
  • 0.1651Inherited
    52540,52540
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.2254Inherited
    48726,49265
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 0.2921Inherited
    50044,50044
  • 50044 - SH3-domain
  • 50044 - SH3-domain
  • 0.3869Inherited
    48726,48726
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 0.4469Inherited
    49313,49313
  • 49313 - Cadherin-like
  • 49313 - Cadherin-like
  • 0.4555Inherited
    63712,90112
  • 63712 - Nicotinic receptor ligand binding domain-like
  • 90112 - Neurotransmitter-gated ion-channel transmembrane pore
  • 0.6289Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    57603,57603,57603
  • 57603 - FnI-like domain
  • 57603 - FnI-like domain
  • 57603 - FnI-like domain
  • 0.001718Inherited
    57196,57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.001807Inherited
    57196,57196,57184
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 0.003798Inherited
    69179,69179,69179
  • 69179 - Integrin domains
  • 69179 - Integrin domains
  • 69179 - Integrin domains
  • 0.04281Inherited
    52540,52540,52540
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.04491Inherited
    48726,48726,48726
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 0.06632Inherited
    69318,69179,69179
  • 69318 - Integrin alpha N-terminal domain
  • 69179 - Integrin domains
  • 69179 - Integrin domains
  • 0.06713Inherited
    48726,48726,49265
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 0.0816Inherited
    50156,50044,52540
  • 50156 - PDZ domain-like
  • 50044 - SH3-domain
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.1651Inherited
    50044,55550,56112
  • 50044 - SH3-domain
  • 55550 - SH2 domain
  • 56112 - Protein kinase-like (PK-like)
  • 0.3538Inherited
    49313,49313,49313
  • 49313 - Cadherin-like
  • 49313 - Cadherin-like
  • 49313 - Cadherin-like
  • 0.4075Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
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