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Mammalian Phenotype (MP): hearing/vestibular/ear phenotype

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Root: MP Hierarchy (mammalian/mouse phenotype from MGI_4.41)

Shortest distance to current term (+ for parents, - for children) MP term [MP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ 1:   mammalian phenotype [MP:0000001] <29>
0:   hearing/vestibular/ear phenotype [MP:0005377] <2>(20|23) (23|14|5)
- 1:   abnormal ear physiology [MP:0003878] <9>(8|8) (8|3|0)
- 1:   abnormal ear morphology [MP:0002102] <4>(16|20) (18|14|5)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
Homeodomain-like0.0000003161Direct
Nuclear receptor ligand-binding domain0.00005846Direct
Glucocorticoid receptor-like (DNA-binding domain)0.000508Direct
Growth factor receptor domain0.001307Inherited
Serine protease inhibitors0.002115Inherited
EGF/Laminin0.004023Inherited
Frizzled cysteine-rich domain0.004816Inherited
Phoshotransferase/anion transport protein0.006086Inherited
Nicotinic receptor ligand binding domain-like0.01302Inherited
Neurotransmitter-gated ion-channel transmembrane pore0.01302Inherited
lambda repressor-like DNA-binding domains0.0474Inherited
Cytokine0.07078Inherited
Second domain of FERM0.07351Inherited
Cadherin-like0.1068Inherited
Cystine-knot cytokines0.1351Inherited
SH3-domain0.1959Inherited
(Trans)glycosidases0.2198Inherited
DEATH domain0.2699Inherited
Voltage-gated potassium channels0.2938Inherited
PDZ domain-like0.3618Inherited


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Family

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SCOP termFDR (all)Annotation (direct or inherited)
Retinoblastoma tumor suppressor domains0Direct
Homeodomain0.0000004469Direct
Nuclear receptor0.00002154Direct
Nuclear receptor ligand-binding domain0.00003738Direct
Paired domain0.0002352Direct
DIX domain0.000242Direct
Clathrin adaptor core protein0.0004822Direct
Forkhead DNA-binding domain0.002996Inherited
Frizzled cysteine-rich domain0.00336Inherited
Phosphotyrosine-binding domain (PTB)0.003644Inherited
Growth factor receptor domain0.004658Inherited
Motor proteins0.006183Inherited
POU-specific domain0.008803Inherited
Nicotinic receptor ligand binding domain-like0.009734Inherited
Neurotransmitter-gated ion-channel transmembrane pore0.009734Inherited
Fibroblast growth factors (FGF)0.02644Inherited
DEP domain0.03304Inherited
Transforming growth factor (TGF)-beta0.07407Inherited
Cadherin0.07407Inherited
EGF-type module0.1063Inherited
SH3-domain0.1803Inherited
Voltage-gated potassium channels0.224Inherited
PDZ domain0.2434Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Homeodomain-like0.0000001267Direct
Nuclear receptor ligand-binding domain0.00002754Direct
Glucocorticoid receptor-like (DNA-binding domain)0.0002687Direct
FnI-like domain0.0007048Direct
Growth factor receptor domain0.0007255Direct
Serine protease inhibitors0.001206Inherited
EGF/Laminin0.002373Inherited
Frizzled cysteine-rich domain0.002878Inherited
Phoshotransferase/anion transport protein0.003688Inherited
Neurotransmitter-gated ion-channel transmembrane pore0.008289Inherited
Nicotinic receptor ligand binding domain-like0.008289Inherited
lambda repressor-like DNA-binding domains0.03341Inherited
Cytokine0.05181Inherited
Second domain of FERM0.05399Inherited
Transducin (alpha subunit), insertion domain0.07223Inherited
Cadherin-like0.08125Inherited
Cystine-knot cytokines0.1058Inherited
SH3-domain0.1596Inherited
(Trans)glycosidases0.1817Inherited
DEATH domain0.2284Inherited
Voltage-gated potassium channels0.251Inherited
PDZ domain-like0.3161Inherited
GTPase activation domain, GAP0.6218Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
57716,48508
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 48508 - Nuclear receptor ligand-binding domain
  • 0.0000005216Direct
    57196,57184
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 0.0005156Direct
    57184,57196
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 0.0005161Direct
    57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.0006775Direct
    49562,48350
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 48350 - GTPase activation domain, GAP
  • 0.006539Inherited
    63712,90112
  • 63712 - Nicotinic receptor ligand binding domain-like
  • 90112 - Neurotransmitter-gated ion-channel transmembrane pore
  • 0.008289Inherited
    49899,57196
  • 49899 - Concanavalin A-like lectins/glucanases
  • 57196 - EGF/Laminin
  • 0.01523Inherited
    47413,46689
  • 47413 - lambda repressor-like DNA-binding domains
  • 46689 - Homeodomain-like
  • 0.01587Inherited
    47895,52540
  • 47895 - Transducin (alpha subunit), insertion domain
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.0603Inherited
    49313,49313
  • 49313 - Cadherin-like
  • 49313 - Cadherin-like
  • 0.06036Inherited
    52058,52058
  • 52058 - L domain-like
  • 52058 - L domain-like
  • 0.07141Inherited
    50156,50156
  • 50156 - PDZ domain-like
  • 50156 - PDZ domain-like
  • 0.1539Inherited
    50044,55550
  • 50044 - SH3-domain
  • 55550 - SH2 domain
  • 0.1539Inherited
    57716,57716
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 0.2187Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    57196,57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.0001225Direct
    57196,57184,57196
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 0.0007455Direct
    57196,57196,57184
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 0.001963Inherited
    57184,57196,57196
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.001963Inherited
    49313,49313,49313
  • 49313 - Cadherin-like
  • 49313 - Cadherin-like
  • 49313 - Cadherin-like
  • 0.04822Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
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