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Mammalian Phenotype (MP): craniofacial phenotype

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Root: MP Hierarchy (mammalian/mouse phenotype from MGI_4.41)

Shortest distance to current term (+ for parents, - for children) MP term [MP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ 1:   mammalian phenotype [MP:0000001] <29>
0:   craniofacial phenotype [MP:0005382] <1>(20|36) (24|17|10)
- 1:   abnormal craniofacial morphology [MP:0000428] <5>(20|36) (24|17|10)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
Homeodomain-like0Direct
p53 tetramerization domain0Direct
SMAD MH1 domain0.000002306Direct
p53-like transcription factors0.00001014Direct
Cystine-knot cytokines0.000108Direct
Growth factor receptor domain0.0001086Direct
EGF/Laminin0.00128Inherited
FnI-like domain0.004663Inherited
Intermediate filament protein, coiled coil region0.005182Inherited
TB module/8-cys domain0.01009Inherited
Bromodomain0.03372Inherited
Metalloproteases ("zincins"), catalytic domain0.03981Inherited
PGBD-like0.06901Inherited
Nuclear receptor ligand-binding domain0.0862Inherited
Hemopexin-like domain0.1147Inherited
lambda repressor-like DNA-binding domains0.1695Inherited
(Trans)glycosidases0.1889Inherited
Transducin (alpha subunit), insertion domain0.2292Inherited
4-helical cytokines0.3238Inherited
Family A G protein-coupled receptor-like1Inherited


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Family

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SCOP termFDR (all)Annotation (direct or inherited)
Retinoblastoma tumor suppressor domains0Direct
p53 DNA-binding domain-like0Direct
p53 tetramerization domain0Direct
Homeodomain0.000000000000007858Direct
SMAD domain0.000001559Direct
SMAD MH1 domain0.000001559Direct
Paired domain0.0000104Direct
Forkhead DNA-binding domain0.0001767Direct
T-box0.0007761Direct
Transforming growth factor (TGF)-beta0.0008935Direct
CalX-beta domain0.0009107Direct
Growth factor receptor domain0.001274Inherited
Arylsulfatase0.002042Inherited
Multidrug efflux transporter AcrB transmembrane domain0.002146Inherited
TNF receptor-like0.002561Inherited
Rel/Dorsal transcription factors, DNA-binding domain0.003922Inherited
Intermediate filament protein, coiled coil region0.004609Inherited
Laminin-type module0.005659Inherited
TB module/8-cys domain0.007835Inherited
Pyridoxal-dependent decarboxylase0.01535Inherited
VWC domain0.01546Inherited
Extracellular domain of cell surface receptors0.02095Inherited
NF-kappa-B/REL/DORSAL transcription factors, C-terminal domain0.02172Inherited
Ephrin ectodomain0.02683Inherited
Neutral endopeptidase (neprilysin)0.02683Inherited
Bromodomain0.02977Inherited
MMP N-terminal domain0.06054Inherited
I set domains0.0646Inherited
Nuclear receptor0.06523Inherited
Matrix metalloproteases, catalytic domain0.07376Inherited
Nuclear receptor ligand-binding domain0.08164Inherited
Hemopexin-like domain0.1042Inherited
DEATH domain, DD0.1282Inherited
Transducin (alpha subunit), insertion domain0.2127Inherited
G proteins0.4187Inherited
Rhodopsin-like1Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
p53 tetramerization domain0Direct
Homeodomain-like0Direct
SMAD MH1 domain0.0000009593Direct
p53-like transcription factors0.000004453Direct
Cystine-knot cytokines0.00005246Direct
Growth factor receptor domain0.00005279Direct
CalX-like0.0006947Direct
EGF/Laminin0.0007102Direct
Protein kinase-like (PK-like)0.0009007Direct
FnI-like domain0.002779Inherited
Intermediate filament protein, coiled coil region0.003109Inherited
TB module/8-cys domain0.006312Inherited
Orange domain-like0.02288Inherited
Bromodomain0.02314Inherited
Metalloproteases ("zincins"), catalytic domain0.02764Inherited
PGBD-like0.05044Inherited
Nuclear receptor ligand-binding domain0.06413Inherited
Snake toxin-like0.06603Inherited
Hemopexin-like domain0.08815Inherited
lambda repressor-like DNA-binding domains0.1357Inherited
(Trans)glycosidases0.1532Inherited
Transducin (alpha subunit), insertion domain0.1904Inherited
4-helical cytokines0.2796Inherited
Family A G protein-coupled receptor-like1Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
49417,47719
  • 49417 - p53-like transcription factors
  • 47719 - p53 tetramerization domain
  • 0Direct
    57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.000436Direct
    57184,57184
  • 57184 - Growth factor receptor domain
  • 57184 - Growth factor receptor domain
  • 0.0005493Direct
    57196,63825
  • 57196 - EGF/Laminin
  • 63825 - YWTD domain
  • 0.001227Inherited
    46579,64593
  • 46579 - Prefoldin
  • 64593 - Intermediate filament protein, coiled coil region
  • 0.001747Inherited
    57184,57196
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 0.002014Inherited
    49417,81296
  • 49417 - p53-like transcription factors
  • 81296 - E set domains
  • 0.003048Inherited
    57603,57603
  • 57603 - FnI-like domain
  • 57603 - FnI-like domain
  • 0.003142Inherited
    64593,64593
  • 64593 - Intermediate filament protein, coiled coil region
  • 64593 - Intermediate filament protein, coiled coil region
  • 0.008316Inherited
    57581,57196
  • 57581 - TB module/8-cys domain
  • 57196 - EGF/Laminin
  • 0.01282Inherited
    57196,57581
  • 57196 - EGF/Laminin
  • 57581 - TB module/8-cys domain
  • 0.01282Inherited
    141072,141072
  • 141072 - CalX-like
  • 141072 - CalX-like
  • 0.01282Inherited
    47459,158457
  • 47459 - HLH, helix-loop-helix DNA-binding domain
  • 158457 - Orange domain-like
  • 0.02288Inherited
    57716,48508
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 48508 - Nuclear receptor ligand-binding domain
  • 0.03319Inherited
    47090,55486
  • 47090 - PGBD-like
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 0.05044Inherited
    47413,46689
  • 47413 - lambda repressor-like DNA-binding domains
  • 46689 - Homeodomain-like
  • 0.07435Inherited
    47895,52540
  • 47895 - Transducin (alpha subunit), insertion domain
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.1633Inherited

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    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    57196,57184,57196
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 0.00007598Direct
    48726,48726,48726
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 0.0005687Direct
    63825,57196,63825
  • 63825 - YWTD domain
  • 57196 - EGF/Laminin
  • 63825 - YWTD domain
  • 0.001227Inherited
    57184,57196,57196
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.002482Inherited
    57184,57184,57184
  • 57184 - Growth factor receptor domain
  • 57184 - Growth factor receptor domain
  • 57184 - Growth factor receptor domain
  • 0.003142Inherited
    57581,57196,57196
  • 57581 - TB module/8-cys domain
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.005916Inherited
    57196,57196,57581
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 57581 - TB module/8-cys domain
  • 0.005916Inherited
    57603,57603,57603
  • 57603 - FnI-like domain
  • 57603 - FnI-like domain
  • 57603 - FnI-like domain
  • 0.01282Inherited
    48726,48726,49265
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 0.02282Inherited
    52540,52540,52540
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.03577Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
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