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Mammalian Phenotype (MP): abnormal organ of Corti morphology

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Root: MP Hierarchy (mammalian/mouse phenotype from MGI_4.41)

Shortest distance to current term (+ for parents, - for children) MP term [MP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + + + + 7:   mammalian phenotype [MP:0000001] <29>
+ + + + + 5:   hearing/vestibular/ear phenotype [MP:0005377] <2>(20|24) (23|14|5)
+ + + + 4:   abnormal ear morphology [MP:0002102] <4>(16|21) (18|14|5)
+ + + 3:   abnormal inner ear morphology [MP:0000026] <15>(13|15) (13|11|5)
+ + + 3:   abnormal membranous labyrinth morphology [MP:0000035] <2>(11|14) (12|9|5)
+ + 2:   abnormal cochlear labyrinth morphology [MP:0004426] <1>(10|12) (11|8|5)
+ + 2:   abnormal cochlea morphology [MP:0000031] <15>(12|14) (13|8|5)
+ 1:   abnormal scala media morphology [MP:0003169] <9>(10|12) (11|8|5)
0:   abnormal organ of Corti morphology [MP:0000042] <7>(10|12) (10|7|5)
- 1:   abnormal cochlear hair cell morphology [MP:0002622] <6>(10|12) (10|7|5)
- 1:   abnormal organ of Corti supporting cell morphology [MP:0004300] <6>(2|2) (2|2|2)
- 1:   abnormal tunnel of Corti morphology [MP:0013808] <1>(0|0) (0|0|0)
- 1:   abnormal cuticular plate morphology [MP:0010015](0|0) (0|0|0)
- 1:   abnormal patterning of the organ of Corti [MP:0006331](0|0) (0|0|0)
- 1:   absent organ of Corti [MP:0000044](0|0) (0|0|0)
- 1:   organ of Corti degeneration [MP:0000043](0|0) (0|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
Frizzled cysteine-rich domain0.00005976Direct
Nicotinic receptor ligand binding domain-like0.001548Inherited
Neurotransmitter-gated ion-channel transmembrane pore0.001548Inherited
Cadherin-like0.002218Inherited
lambda repressor-like DNA-binding domains0.01263Inherited
PDZ domain-like0.01377Inherited
Second domain of FERM0.03482Inherited
SH3-domain0.408Inherited
Growth factor receptor domain0.4976Inherited
EGF/Laminin0.7553Inherited


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Family

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SCOP termFDR (all)Annotation (direct or inherited)
Frizzled cysteine-rich domain0.00003172Direct
DIX domain0.00004728Direct
DEP domain0.0006142Direct
Neurotransmitter-gated ion-channel transmembrane pore0.0009406Direct
Nicotinic receptor ligand binding domain-like0.0009406Direct
Growth factor receptor domain0.0009979Direct
Cadherin0.001071Inherited
PDZ domain0.001447Inherited
POU-specific domain0.002867Inherited
Motor proteins0.02331Inherited
SH3-domain0.37Inherited
EGF-type module0.6345Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Frizzled cysteine-rich domain0.00002822Direct
Nicotinic receptor ligand binding domain-like0.0008674Direct
Neurotransmitter-gated ion-channel transmembrane pore0.0008674Direct
Cadherin-like0.001266Inherited
lambda repressor-like DNA-binding domains0.008018Inherited
PDZ domain-like0.008805Inherited
Second domain of FERM0.02394Inherited
SH3-domain0.3612Inherited
Growth factor receptor domain0.45Inherited
EGF/Laminin0.7174Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
57196,57184
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 0.000395Direct
    63712,90112
  • 63712 - Nicotinic receptor ligand binding domain-like
  • 90112 - Neurotransmitter-gated ion-channel transmembrane pore
  • 0.0008674Direct
    49313,49313
  • 49313 - Cadherin-like
  • 49313 - Cadherin-like
  • 0.0008674Direct
    50156,50156
  • 50156 - PDZ domain-like
  • 50156 - PDZ domain-like
  • 0.002321Inherited
    47413,46689
  • 47413 - lambda repressor-like DNA-binding domains
  • 46689 - Homeodomain-like
  • 0.004527Inherited
    57184,57196
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 0.008018Inherited
    57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.5383Inherited

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    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    57196,57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.0003532Direct
    57196,57184,57196
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 0.0005677Direct
    49313,49313,49313
  • 49313 - Cadherin-like
  • 49313 - Cadherin-like
  • 49313 - Cadherin-like
  • 0.0006558Direct
    57196,57196,57184
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 0.001052Inherited
    57184,57196,57196
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.001052Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
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