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Mammalian Phenotype (MP): abnormal craniofacial morphology

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Root: MP Hierarchy (mammalian/mouse phenotype from MGI_4.41)

Shortest distance to current term (+ for parents, - for children) MP term [MP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + 2:   mammalian phenotype [MP:0000001] <30>
+ 1:   craniofacial phenotype [MP:0005382] <1>(20|35) (23|16|10)
0:   abnormal craniofacial morphology [MP:0000428] <5>(20|34) (23|15|10)
- 1:   abnormal outer ear morphology [MP:0002177] <19>(0|1) (2|1|0)
- 1:   abnormal craniofacial development [MP:0003935] <17>(6|7) (6|1|2)
- 1:   abnormal facial morphology [MP:0003743] <9>(8|20) (10|6|3)
- 1:   abnormal head shape [MP:0011495] <7>(1|0) (1|0|0)
- 1:   abnormal craniofacial bone morphology [MP:0002116] <3>(13|22) (14|12|7)


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
Transducin (alpha subunit), insertion domain1Inherited
Snake toxin-like1Inherited
SMAD MH1 domain1Inherited
Bromodomain1Inherited
(Trans)glycosidases1Inherited
FnI-like domain1Inherited
Intermediate filament protein, coiled coil region1Inherited
Hemopexin-like domain1Inherited
TB module/8-cys domain1Inherited
Nuclear receptor ligand-binding domain1Inherited
Family A G protein-coupled receptor-like1Inherited
Cystine-knot cytokines1Inherited
4-helical cytokines1Inherited
p53 tetramerization domain1Inherited
Alkaline phosphatase-like1Inherited
PGBD-like1Inherited
p53-like transcription factors1Inherited
Growth factor receptor domain1Inherited
Homeodomain-like1Inherited
Metalloproteases ("zincins"), catalytic domain1Inherited


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

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SCOP termFDR (all)Annotation (direct or inherited)
Rel/Dorsal transcription factors, DNA-binding domain1Inherited
Retinoblastoma tumor suppressor domains1Inherited
Forkhead DNA-binding domain1Inherited
CalX-beta domain1Inherited
T-box1Inherited
Pyridoxal-dependent decarboxylase1Inherited
DEATH domain, DD1Inherited
Rhodopsin-like1Inherited
Transducin (alpha subunit), insertion domain1Inherited
Neutral endopeptidase (neprilysin)1Inherited
MMP N-terminal domain1Inherited
Matrix metalloproteases, catalytic domain1Inherited
Homeodomain1Inherited
Transforming growth factor (TGF)-beta1Inherited
Paired domain1Inherited
Multidrug efflux transporter AcrB transmembrane domain1Inherited
p53 tetramerization domain1Inherited
SMAD MH1 domain1Inherited
G proteins1Inherited
Nuclear receptor ligand-binding domain1Inherited
SMAD domain1Inherited
Hemopexin-like domain1Inherited
Intermediate filament protein, coiled coil region1Inherited
Extracellular domain of cell surface receptors1Inherited
Higher-molecular-weight phosphotyrosine protein phosphatases1Inherited
Nuclear receptor1Inherited
I set domains1Inherited
Laminin-type module1Inherited
Arylsulfatase1Inherited
Bromodomain1Inherited
TB module/8-cys domain1Inherited
p53 DNA-binding domain-like1Inherited
Growth factor receptor domain1Inherited
VWC domain1Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Intermediate filament protein, coiled coil region1Inherited
Cystine-knot cytokines1Inherited
FnI-like domain1Inherited
(Trans)glycosidases1Inherited
Cyclin-like1Inherited
Nuclear receptor ligand-binding domain1Inherited
Growth factor receptor domain1Inherited
Bromodomain1Inherited
Family A G protein-coupled receptor-like1Inherited
p53-like transcription factors1Inherited
HLH, helix-loop-helix DNA-binding domain1Inherited
Transducin (alpha subunit), insertion domain1Inherited
SMAD MH1 domain1Inherited
PGBD-like1Inherited
Snake toxin-like1Inherited
Homeodomain-like1Inherited
CalX-like1Inherited
p53 tetramerization domain1Inherited
Alkaline phosphatase-like1Inherited
Hemopexin-like domain1Inherited
4-helical cytokines1Inherited
TB module/8-cys domain1Inherited
Metalloproteases ("zincins"), catalytic domain1Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
57603,57603
  • 57603 - FnI-like domain
  • 57603 - FnI-like domain
  • 1Inherited
    57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 1Inherited
    49417,81296
  • 49417 - p53-like transcription factors
  • 81296 - E set domains
  • 1Inherited
    47090,55486
  • 47090 - PGBD-like
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 1Inherited
    49417,47719
  • 49417 - p53-like transcription factors
  • 47719 - p53 tetramerization domain
  • 1Inherited
    57581,57196
  • 57581 - TB module/8-cys domain
  • 57196 - EGF/Laminin
  • 1Inherited
    57716,48508
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 48508 - Nuclear receptor ligand-binding domain
  • 1Inherited
    52540,52540
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 1Inherited
    64593,64593
  • 64593 - Intermediate filament protein, coiled coil region
  • 64593 - Intermediate filament protein, coiled coil region
  • 1Inherited
    57196,63825
  • 57196 - EGF/Laminin
  • 63825 - YWTD domain
  • 1Inherited
    57184,57196
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 1Inherited
    57424,57424
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 1Inherited
    57184,57184
  • 57184 - Growth factor receptor domain
  • 57184 - Growth factor receptor domain
  • 1Inherited
    47895,52540
  • 47895 - Transducin (alpha subunit), insertion domain
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 1Inherited
    57196,57581
  • 57196 - EGF/Laminin
  • 57581 - TB module/8-cys domain
  • 1Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    57184,57184,57184
  • 57184 - Growth factor receptor domain
  • 57184 - Growth factor receptor domain
  • 57184 - Growth factor receptor domain
  • 1Inherited
    57196,57196,57581
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 57581 - TB module/8-cys domain
  • 1Inherited
    57424,57424,57424
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 1Inherited
    57196,57184,57196
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 1Inherited
    57603,57603,57603
  • 57603 - FnI-like domain
  • 57603 - FnI-like domain
  • 57603 - FnI-like domain
  • 1Inherited
    52540,52540,52540
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 1Inherited
    57581,57196,57196
  • 57581 - TB module/8-cys domain
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 1Inherited
    48726,48726,49265
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 1Inherited
    57184,57196,57196
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 1Inherited
    48726,48726,48726
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 1Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
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