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Mammalian Phenotype (MP): abnormal renal/urinary system morphology

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Root: MP Hierarchy (mammalian/mouse phenotype from MGI_4.41)

Shortest distance to current term (+ for parents, - for children) MP term [MP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + 2:   mammalian phenotype [MP:0000001] <29>
+ 1:   renal/urinary system phenotype [MP:0005367] <2>(41|47) (46|26|11)
0:   abnormal renal/urinary system morphology [MP:0000516] <14>(31|36) (36|22|11)
- 1:   abnormal kidney morphology [MP:0002135] <29>(26|28) (28|15|6)
- 1:   abnormal urinary bladder morphology [MP:0000538] <22>(2|2) (2|1|0)
- 1:   abnormal ureter morphology [MP:0000534] <18>(4|5) (4|6|5)
- 1:   abnormal urethra morphology [MP:0000537] <14>(0|0) (0|0|0)
- 1:   abnormal penis morphology [MP:0005187] <9>(0|1) (1|0|0)
- 1:   increased urinary system tumor incidence [MP:0010289] <5>(2|1) (2|0|0)
- 1:   abnormal urinary system development [MP:0003942] <4>(2|5) (6|3|2)
- 1:   abnormal urothelium morphology [MP:0003630] <4>(2|3) (2|1|0)
- 1:   abnormal ureteropelvic junction morphology [MP:0011487] <3>(0|0) (0|0|0)
- 1:   abnormal ureterovesical junction morphology [MP:0011488] <2>(0|0) (0|0|0)
- 1:   urolithiasis [MP:0005360] <2>(2|2) (2|1|0)
- 1:   abnormal internal urethral orifice morphology [MP:0011782](0|0) (0|0|0)
- 1:   decreased urinary system tumor incidence [MP:0012427](0|0) (0|0|0)
- 1:   persistent cloaca [MP:0003129](0|0) (0|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
Nitric oxide (NO) synthase oxygenase domain0Direct
Cystine-knot cytokines0.0001411Direct
Families 57/38 glycoside transferase middle domain0.0002903Direct
Notch domain0.0002903Direct
Glycoside hydrolase/deacetylase0.001149Inherited
Flavoproteins0.00286Inherited
Galactose mutarotase-like0.00286Inherited
Plexin repeat0.002956Inherited
CalX-like0.005676Inherited
Sema domain0.01511Inherited
TNF receptor-like0.0202Inherited
HCP-like0.02161Inherited
L30e-like0.03338Inherited
Bcl-2 inhibitors of programmed cell death0.06375Inherited
ARM repeat0.06402Inherited
TPR-like0.1092Inherited
Cyclin-like0.1371Inherited
Glucocorticoid receptor-like (DNA-binding domain)0.139Inherited
Cadherin-like0.2305Inherited
FnI-like domain0.2443Inherited
Metalloproteases ("zincins"), catalytic domain0.2898Inherited
Homeodomain-like0.3079Inherited
Integrin domains0.3364Inherited
(Trans)glycosidases0.3467Inherited
Nuclear receptor ligand-binding domain0.3904Inherited
C-type lectin-like0.4137Inherited
Neurotransmitter-gated ion-channel transmembrane pore0.4787Inherited
Nicotinic receptor ligand binding domain-like0.4787Inherited
Integrin alpha N-terminal domain0.7428Inherited
Riboflavin synthase domain-like0.7428Inherited
Ferredoxin reductase-like, C-terminal NADP-linked domain0.7428Inherited


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Family

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SCOP termFDR (all)Annotation (direct or inherited)
Nitric oxide (NO) synthase oxygenase domain0Direct
Cytochrome p450 reductase N-terminal domain-like0Direct
Retinoblastoma tumor suppressor domains0Direct
EGF-type module0.0001418Direct
alpha-mannosidase, domain 20.0001847Direct
NADPH-cytochrome p450 reductase-like0.0001847Direct
alpha-mannosidase0.0001847Direct
Notch domain0.0001847Direct
NADPH-cytochrome p450 reductase FAD-binding domain-like0.0001847Direct
Transforming growth factor (TGF)-beta0.0006695Direct
Noncollagenous (NC1) domain of collagen IV0.0007663Direct
alpha-mannosidase, C-terminal domain0.001215Inherited
Plexin repeat0.002321Inherited
CalX-beta domain0.004099Inherited
Platelet-derived growth factor-like0.004099Inherited
Phoshoinositide 3-kinase (PI3K), catalytic domain0.007627Inherited
Laminin-type module0.009442Inherited
Sema domain0.01219Inherited
TNF receptor-like0.02008Inherited
Bcl-2 inhibitors of programmed cell death0.05187Inherited
Short-chain cytokines0.1052Inherited
Tetratricopeptide repeat (TPR)0.1586Inherited
Fibroblast growth factors (FGF)0.1625Inherited
Cadherin0.1832Inherited
Forkhead DNA-binding domain0.222Inherited
Integrin domains0.3112Inherited
VWC domain0.3112Inherited
Nuclear receptor ligand-binding domain0.3706Inherited
Nuclear receptor0.3706Inherited
I set domains0.3831Inherited
Leucine zipper domain0.3854Inherited
Integrin alpha N-terminal domain0.4359Inherited
Neurotransmitter-gated ion-channel transmembrane pore0.4615Inherited
Nicotinic receptor ligand binding domain-like0.4615Inherited
Homeodomain0.5645Inherited
Rhodopsin-like1Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Nitric oxide (NO) synthase oxygenase domain0Direct
Cystine-knot cytokines0.00007019Direct
Families 57/38 glycoside transferase middle domain0.0001489Direct
Notch domain0.0001489Direct
Glycoside hydrolase/deacetylase0.000631Direct
Flavoproteins0.001652Inherited
Galactose mutarotase-like0.001652Inherited
Plexin repeat0.00171Inherited
CalX-like0.003423Inherited
EGF/Laminin0.005789Inherited
Sema domain0.00971Inherited
TNF receptor-like0.01328Inherited
Growth factor receptor domain0.01375Inherited
HCP-like0.01428Inherited
L30e-like0.02288Inherited
Bcl-2 inhibitors of programmed cell death0.04624Inherited
ARM repeat0.04644Inherited
TPR-like0.08334Inherited
Cyclin-like0.1075Inherited
Glucocorticoid receptor-like (DNA-binding domain)0.1091Inherited
Cadherin-like0.1916Inherited
FnI-like domain0.2045Inherited
Cytokine0.2412Inherited
Metalloproteases ("zincins"), catalytic domain0.2472Inherited
Homeodomain-like0.2643Inherited
Integrin domains0.2914Inherited
(Trans)glycosidases0.3015Inherited
Nuclear receptor ligand-binding domain0.344Inherited
Leucine zipper domain0.3526Inherited
C-type lectin-like0.3669Inherited
Nicotinic receptor ligand binding domain-like0.4311Inherited
Neurotransmitter-gated ion-channel transmembrane pore0.4311Inherited
Ferredoxin reductase-like, C-terminal NADP-linked domain0.7044Inherited
Riboflavin synthase domain-like0.7044Inherited
Integrin alpha N-terminal domain0.7044Inherited
Family A G protein-coupled receptor-like0.9994Inherited

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
88713,88688
  • 88713 - Glycoside hydrolase/deacetylase
  • 88688 - Families 57/38 glycoside transferase middle domain
  • 0.0001489Direct
    57184,57196
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 0.0006407Direct
    57196,90193
  • 57196 - EGF/Laminin
  • 90193 - Notch domain
  • 0.001025Inherited
    48452,81901
  • 48452 - TPR-like
  • 81901 - HCP-like
  • 0.001025Inherited
    57184,57184
  • 57184 - Growth factor receptor domain
  • 57184 - Growth factor receptor domain
  • 0.001125Inherited
    57603,57603
  • 57603 - FnI-like domain
  • 57603 - FnI-like domain
  • 0.001652Inherited
    57196,57184
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 0.00244Inherited
    52799,49562
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 0.007935Inherited
    101912,103575
  • 101912 - Sema domain
  • 103575 - Plexin repeat
  • 0.00971Inherited
    50044,55550
  • 50044 - SH3-domain
  • 55550 - SH2 domain
  • 0.02792Inherited
    56436,56436
  • 56436 - C-type lectin-like
  • 56436 - C-type lectin-like
  • 0.0573Inherited
    57586,57586
  • 57586 - TNF receptor-like
  • 57586 - TNF receptor-like
  • 0.07685Inherited
    50156,50044
  • 50156 - PDZ domain-like
  • 50044 - SH3-domain
  • 0.09469Inherited
    57716,48508
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 48508 - Nuclear receptor ligand-binding domain
  • 0.1712Inherited
    52540,52540
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.2045Inherited
    50044,50044
  • 50044 - SH3-domain
  • 50044 - SH3-domain
  • 0.2483Inherited
    49313,49313
  • 49313 - Cadherin-like
  • 49313 - Cadherin-like
  • 0.2677Inherited
    48726,48726
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 0.2871Inherited
    48726,49265
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 0.2914Inherited
    69179,69179
  • 69179 - Integrin domains
  • 69179 - Integrin domains
  • 0.4155Inherited
    69318,69179
  • 69318 - Integrin alpha N-terminal domain
  • 69179 - Integrin domains
  • 0.4155Inherited
    63712,90112
  • 63712 - Nicotinic receptor ligand binding domain-like
  • 90112 - Neurotransmitter-gated ion-channel transmembrane pore
  • 0.4311Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    57196,57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.0002345Direct
    57603,57603,57603
  • 57603 - FnI-like domain
  • 57603 - FnI-like domain
  • 57603 - FnI-like domain
  • 0.000631Direct
    57196,57196,57184
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 0.001059Inherited
    52540,52540,52540
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.02288Inherited
    50156,50044,52540
  • 50156 - PDZ domain-like
  • 50044 - SH3-domain
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.09469Inherited
    48726,48726,48726
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 0.1118Inherited
    50044,55550,56112
  • 50044 - SH3-domain
  • 55550 - SH2 domain
  • 56112 - Protein kinase-like (PK-like)
  • 0.2246Inherited
    49313,49313,49313
  • 49313 - Cadherin-like
  • 49313 - Cadherin-like
  • 49313 - Cadherin-like
  • 0.2319Inherited
    48726,48726,49265
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 0.3475Inherited
    69318,69179,69179
  • 69318 - Integrin alpha N-terminal domain
  • 69179 - Integrin domains
  • 69179 - Integrin domains
  • 0.4155Inherited
    69179,69179,69179
  • 69179 - Integrin domains
  • 69179 - Integrin domains
  • 69179 - Integrin domains
  • 0.4155Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
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