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Mammalian Phenotype (MP): abnormal forebrain morphology

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Root: MP Hierarchy (mammalian/mouse phenotype from MGI_4.41)

Shortest distance to current term (+ for parents, - for children) MP term [MP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + 4:   mammalian phenotype [MP:0000001] <29>
+ + + 3:   nervous system phenotype [MP:0003631] <2>(98|127) (112|79|50)
+ + 2:   abnormal nervous system morphology [MP:0003632] <17>(76|104) (91|64|47)
+ 1:   abnormal brain morphology [MP:0002152] <24>(25|42) (35|24|14)
0:   abnormal forebrain morphology [MP:0000783] <8>(18|26) (24|15|8)
- 1:   abnormal diencephalon morphology [MP:0000830] <11>(4|5) (6|1|0)
- 1:   abnormal telencephalon morphology [MP:0000787] <9>(15|22) (19|12|6)
- 1:   abnormal limbic system morphology [MP:0004166] <6>(7|8) (9|5|2)
- 1:   abnormal basal ganglion morphology [MP:0006007] <5>(2|4) (2|0|0)
- 1:   abnormal forebrain development [MP:0003232] <2>(3|5) (3|1|0)
- 1:   abnormal forebrain size [MP:0012137] <2>(0|0) (0|0|0)
- 1:   absent forebrain [MP:0012136](0|0) (0|0|0)
- 1:   forebrain atrophy [MP:0012508](0|0) (0|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
Vasodilator-stimulated phosphoprotein, VASP, tetramerisation domain0Direct
Homeodomain-like0.006094Inherited
Doublecortin (DC)0.03084Inherited
Glucocorticoid receptor-like (DNA-binding domain)0.03873Inherited
lambda repressor-like DNA-binding domains0.06544Inherited
SH3-domain0.1112Inherited
Nuclear receptor ligand-binding domain0.1226Inherited
HLH, helix-loop-helix DNA-binding domain0.1514Inherited
Sema domain0.1643Inherited
SAP domain0.1889Inherited
Plexin repeat0.2237Inherited
Metallo-dependent hydrolases0.2259Inherited
Composite domain of metallo-dependent hydrolases0.2259Inherited
cAMP-binding domain-like0.3206Inherited
Cupredoxins0.4457Inherited
EGF/Laminin0.6Inherited
Family A G protein-coupled receptor-like0.7698Inherited
Growth factor receptor domain0.8379Inherited


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Family

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SCOP termFDR (all)Annotation (direct or inherited)
Other IPT/TIG domains0Direct
Vasodilator-stimulated phosphoprotein, VASP, tetramerisation domain0Direct
Hypoxia-inducible factor Hif2a, C-terminal domain0.000801Direct
beta-glycanases0.001962Inherited
Multidrug efflux transporter AcrB transmembrane domain0.001962Inherited
Enabled/VASP homology 1 domain (EVH1 domain)0.01913Inherited
Doublecortin (DC)0.0249Inherited
Homeodomain0.02676Inherited
Ngr ectodomain-like0.04844Inherited
SH3-domain0.1042Inherited
Nuclear receptor ligand-binding domain0.1091Inherited
Nuclear receptor0.1091Inherited
HLH, helix-loop-helix DNA-binding domain0.1426Inherited
Sema domain0.1468Inherited
SAP domain0.1732Inherited
cAMP-binding domain0.1842Inherited
Ephrin ectodomain0.201Inherited
Hydantoinase (dihydropyrimidinase), catalytic domain0.201Inherited
Hydantoinase (dihydropyrimidinase)0.201Inherited
Ephrin receptor ligand binding domain0.201Inherited
Plexin repeat0.2063Inherited
Voltage-gated potassium channels0.35Inherited
Phosphotyrosine-binding domain (PTB)0.3537Inherited
SAM (sterile alpha motif) domain0.3537Inherited
EGF-type module0.5912Inherited
Rhodopsin-like0.8416Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Vasodilator-stimulated phosphoprotein, VASP, tetramerisation domain0Direct
Homeodomain-like0.003694Inherited
Doublecortin (DC)0.02104Inherited
Glucocorticoid receptor-like (DNA-binding domain)0.02681Inherited
Multidrug efflux transporter AcrB transmembrane domain0.03302Inherited
lambda repressor-like DNA-binding domains0.04755Inherited
SH3-domain0.08511Inherited
Nuclear receptor ligand-binding domain0.09475Inherited
HLH, helix-loop-helix DNA-binding domain0.12Inherited
Sema domain0.1312Inherited
L domain-like0.142Inherited
SAP domain0.1533Inherited
GTPase activation domain, GAP0.1623Inherited
Plexin repeat0.1853Inherited
Metallo-dependent hydrolases0.1875Inherited
Composite domain of metallo-dependent hydrolases0.1875Inherited
Glutamine synthetase/guanido kinase0.2622Inherited
cAMP-binding domain-like0.2766Inherited
Cupredoxins0.3981Inherited
E set domains0.4416Inherited
Voltage-gated potassium channels0.4501Inherited
EGF/Laminin0.5545Inherited
Family A G protein-coupled receptor-like0.7325Inherited
Growth factor receptor domain0.806Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
57196,57424
  • 57196 - EGF/Laminin
  • 57424 - LDL receptor-like module
  • 0Direct
    63825,57196
  • 63825 - YWTD domain
  • 57196 - EGF/Laminin
  • 0.0001191Direct
    48452,81901
  • 48452 - TPR-like
  • 81901 - HCP-like
  • 0.001582Inherited
    57424,57184
  • 57424 - LDL receptor-like module
  • 57184 - Growth factor receptor domain
  • 0.002791Inherited
    57184,63825
  • 57184 - Growth factor receptor domain
  • 63825 - YWTD domain
  • 0.002791Inherited
    57716,57716
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 0.005361Inherited
    89837,89837
  • 89837 - Doublecortin (DC)
  • 89837 - Doublecortin (DC)
  • 0.02104Inherited
    52058,48726
  • 52058 - L domain-like
  • 48726 - Immunoglobulin
  • 0.1058Inherited
    101912,103575
  • 101912 - Sema domain
  • 103575 - Plexin repeat
  • 0.1312Inherited
    56112,47769
  • 56112 - Protein kinase-like (PK-like)
  • 47769 - SAM/Pointed domain
  • 0.1875Inherited
    51338,51556
  • 51338 - Composite domain of metallo-dependent hydrolases
  • 51556 - Metallo-dependent hydrolases
  • 0.1875Inherited
    51556,51338
  • 51556 - Metallo-dependent hydrolases
  • 51338 - Composite domain of metallo-dependent hydrolases
  • 0.1875Inherited
    81296,81296
  • 81296 - E set domains
  • 81296 - E set domains
  • 0.2394Inherited
    57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.5567Inherited
    103575,48726
  • 103575 - Plexin repeat
  • 48726 - Immunoglobulin
  • 0.6943Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    63825,57196,57424
  • 63825 - YWTD domain
  • 57196 - EGF/Laminin
  • 57424 - LDL receptor-like module
  • 0Direct
    57196,57424,57424
  • 57196 - EGF/Laminin
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 0Direct
    57424,57184,63825
  • 57424 - LDL receptor-like module
  • 57184 - Growth factor receptor domain
  • 63825 - YWTD domain
  • 0.001089Inherited
    57424,57424,57184
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 57184 - Growth factor receptor domain
  • 0.001089Inherited
    48726,48726,49265
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 0.05881Inherited
    51338,51556,51338
  • 51338 - Composite domain of metallo-dependent hydrolases
  • 51556 - Metallo-dependent hydrolases
  • 51338 - Composite domain of metallo-dependent hydrolases
  • 0.1875Inherited
    81296,81296,81296
  • 81296 - E set domains
  • 81296 - E set domains
  • 81296 - E set domains
  • 0.2394Inherited
    101912,103575,48726
  • 101912 - Sema domain
  • 103575 - Plexin repeat
  • 48726 - Immunoglobulin
  • 0.6943Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
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