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Mammalian Phenotype (MP): abnormal somatic sensory system morphology

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Root: MP Hierarchy (mammalian/mouse phenotype from MGI_4.41)

Shortest distance to current term (+ for parents, - for children) MP term [MP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + 4:   mammalian phenotype [MP:0000001] <29>
+ + + 3:   nervous system phenotype [MP:0003631] <2>(98|127) (112|79|50)
+ + 2:   abnormal nervous system morphology [MP:0003632] <17>(76|104) (91|64|47)
+ 1:   abnormal somatic nervous system morphology [MP:0002752] <7>(34|47) (37|25|14)
0:   abnormal somatic sensory system morphology [MP:0000959] <4>(26|38) (29|19|12)
- 1:   abnormal sensory neuron morphology [MP:0000965] <16>(16|28) (19|14|9)
- 1:   abnormal sensory ganglion morphology [MP:0000960] <5>(1|4) (4|2|1)
- 1:   abnormal mechanoreceptor morphology [MP:0000972] <4>(10|12) (10|7|5)
- 1:   abnormal vomeronasal organ morphology [MP:0002243] <3>(0|0) (0|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
Tubby C-terminal domain-like0Direct
GDNF receptor-like0.0008322Direct
Frizzled cysteine-rich domain0.001058Inherited
Notch domain0.00278Inherited
GAF domain-like0.006136Inherited
E2F-DP heterodimerization region0.01103Inherited
Orange domain-like0.01103Inherited
Clc chloride channel0.01737Inherited
HLH, helix-loop-helix DNA-binding domain0.05847Inherited
CBS-domain pair0.07074Inherited
Growth factor receptor domain0.1154Inherited
Family A G protein-coupled receptor-like0.1526Inherited
Second domain of FERM0.1624Inherited
HD-domain/PDEase-like0.1682Inherited
Cystine-knot cytokines0.2397Inherited
Cyclin-like0.302Inherited
Sema domain0.3189Inherited
HMG-box0.3424Inherited
PDZ domain-like0.4113Inherited
Cadherin-like0.479Inherited
Plexin repeat0.5115Inherited
lambda repressor-like DNA-binding domains0.8023Inherited
Nicotinic receptor ligand binding domain-like0.8285Inherited
Neurotransmitter-gated ion-channel transmembrane pore0.8285Inherited
SH3-domain0.8812Inherited
EGF/Laminin0.9248Inherited


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Family

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SCOP termFDR (all)Annotation (direct or inherited)
Retinoblastoma tumor suppressor domains0Direct
Transcriptional factor tubby, C-terminal domain0Direct
Neurotrophin0Direct
L domain0.00004033Direct
Paired domain0.0003037Direct
GDNF receptor-like0.00057Direct
Frizzled cysteine-rich domain0.0008368Direct
Notch domain0.002019Inherited
Growth factor receptor domain0.002362Inherited
Adenylyl and guanylyl cyclase catalytic domain0.004325Inherited
DIX domain0.004639Inherited
E2F dimerization segment0.004639Inherited
GAF domain0.004639Inherited
DEP domain0.007775Inherited
Hairy Orange domain0.008567Inherited
Clc chloride channel0.01378Inherited
Cell cycle transcription factor e2f-dp0.0205Inherited
HLH, helix-loop-helix DNA-binding domain0.04607Inherited
CBS-domain pair0.04896Inherited
cAMP-binding domain0.0594Inherited
Calmodulin-like0.07676Inherited
Rhodopsin-like0.09433Inherited
PDEase0.1199Inherited
Cadherin0.2073Inherited
Motor proteins0.2827Inherited
Sema domain0.2866Inherited
HMG-box0.308Inherited
POU-specific domain0.308Inherited
EGF-type module0.3363Inherited
Rel/Dorsal transcription factors, DNA-binding domain0.3752Inherited
NF-kappa-B/REL/DORSAL transcription factors, C-terminal domain0.3752Inherited
PDZ domain0.4279Inherited
Extracellular domain of cell surface receptors0.4583Inherited
Plexin repeat0.4802Inherited
Nicotinic receptor ligand binding domain-like0.8068Inherited
Neurotransmitter-gated ion-channel transmembrane pore0.8068Inherited
SH3-domain0.8661Inherited
Laminin-type module1Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Tubby C-terminal domain-like0Direct
GDNF receptor-like0.0004493Direct
Frizzled cysteine-rich domain0.0005798Direct
Notch domain0.001606Inherited
Nucleotide cyclase0.003184Inherited
GAF domain-like0.003721Inherited
E2F-DP heterodimerization region0.006947Inherited
Orange domain-like0.006947Inherited
Clc chloride channel0.01132Inherited
HLH, helix-loop-helix DNA-binding domain0.04198Inherited
CBS-domain pair0.05178Inherited
Growth factor receptor domain0.08873Inherited
Family A G protein-coupled receptor-like0.121Inherited
Second domain of FERM0.1295Inherited
HD-domain/PDEase-like0.1345Inherited
"Winged helix" DNA-binding domain0.1993Inherited
Cystine-knot cytokines0.2002Inherited
Cyclin-like0.2587Inherited
Sema domain0.2749Inherited
HMG-box0.2972Inherited
L domain-like0.3157Inherited
PDZ domain-like0.3645Inherited
Cadherin-like0.4315Inherited
Plexin repeat0.4642Inherited
lambda repressor-like DNA-binding domains0.7676Inherited
Neurotransmitter-gated ion-channel transmembrane pore0.7957Inherited
Nicotinic receptor ligand binding domain-like0.7957Inherited
SH3-domain0.8529Inherited
EGF/Laminin0.9003Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
52058,57184
  • 52058 - L domain-like
  • 57184 - Growth factor receptor domain
  • 0.00002805Direct
    57184,52058
  • 57184 - Growth factor receptor domain
  • 52058 - L domain-like
  • 0.00002805Direct
    56112,55073
  • 56112 - Protein kinase-like (PK-like)
  • 55073 - Nucleotide cyclase
  • 0.0006142Direct
    57184,49265
  • 57184 - Growth factor receptor domain
  • 49265 - Fibronectin type III
  • 0.001606Inherited
    55781,55781
  • 55781 - GAF domain-like
  • 55781 - GAF domain-like
  • 0.003721Inherited
    55781,109604
  • 55781 - GAF domain-like
  • 109604 - HD-domain/PDEase-like
  • 0.003721Inherited
    46785,144074
  • 46785 - "Winged helix" DNA-binding domain
  • 144074 - E2F-DP heterodimerization region
  • 0.006947Inherited
    47459,158457
  • 47459 - HLH, helix-loop-helix DNA-binding domain
  • 158457 - Orange domain-like
  • 0.006947Inherited
    52058,48726
  • 52058 - L domain-like
  • 48726 - Immunoglobulin
  • 0.008831Inherited
    57196,57184
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 0.2421Inherited
    49313,49313
  • 49313 - Cadherin-like
  • 49313 - Cadherin-like
  • 0.2421Inherited
    101912,103575
  • 101912 - Sema domain
  • 103575 - Plexin repeat
  • 0.2749Inherited
    50156,50156
  • 50156 - PDZ domain-like
  • 50156 - PDZ domain-like
  • 0.2972Inherited
    81296,81296
  • 81296 - E set domains
  • 81296 - E set domains
  • 0.2972Inherited
    49417,81296
  • 49417 - p53-like transcription factors
  • 81296 - E set domains
  • 0.364Inherited
    47413,46689
  • 47413 - lambda repressor-like DNA-binding domains
  • 46689 - Homeodomain-like
  • 0.5696Inherited
    57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.5901Inherited
    57184,57196
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 0.6477Inherited
    63712,90112
  • 63712 - Nicotinic receptor ligand binding domain-like
  • 90112 - Neurotransmitter-gated ion-channel transmembrane pore
  • 0.7957Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    57184,52058,57184
  • 57184 - Growth factor receptor domain
  • 52058 - L domain-like
  • 57184 - Growth factor receptor domain
  • 0Direct
    52058,48726,48726
  • 52058 - L domain-like
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 0Direct
    52058,57184,52058
  • 52058 - L domain-like
  • 57184 - Growth factor receptor domain
  • 52058 - L domain-like
  • 0.00002805Direct
    57184,49899,49899
  • 57184 - Growth factor receptor domain
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.00005006Direct
    57196,57196,57184
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 0.0002763Direct
    49899,57196,57196
  • 49899 - Concanavalin A-like lectins/glucanases
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.001303Inherited
    57184,57196,57196
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.002148Inherited
    55781,55781,109604
  • 55781 - GAF domain-like
  • 55781 - GAF domain-like
  • 109604 - HD-domain/PDEase-like
  • 0.003721Inherited
    49313,49313,49313
  • 49313 - Cadherin-like
  • 49313 - Cadherin-like
  • 49313 - Cadherin-like
  • 0.2421Inherited
    81296,81296,81296
  • 81296 - E set domains
  • 81296 - E set domains
  • 81296 - E set domains
  • 0.2972Inherited
    57196,57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.3645Inherited
    57196,57184,57196
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 0.4461Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
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