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Mammalian Phenotype (MP): abnormal somatic sensory system morphology

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Root: MP Hierarchy (mammalian/mouse phenotype from MGI_4.41)

Shortest distance to current term (+ for parents, - for children) MP term [MP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + 4:   mammalian phenotype [MP:0000001] <29>
+ + + 3:   nervous system phenotype [MP:0003631] <2>(98|128) (113|79|50)
+ + 2:   abnormal nervous system morphology [MP:0003632] <17>(76|104) (91|64|47)
+ 1:   abnormal somatic nervous system morphology [MP:0002752] <7>(34|47) (37|25|14)
0:   abnormal somatic sensory system morphology [MP:0000959] <4>(26|38) (29|19|12)
- 1:   abnormal sensory neuron morphology [MP:0000965] <16>(16|28) (19|14|9)
- 1:   abnormal sensory ganglion morphology [MP:0000960] <5>(2|4) (4|2|1)
- 1:   abnormal mechanoreceptor morphology [MP:0000972] <4>(10|12) (10|7|5)
- 1:   abnormal vomeronasal organ morphology [MP:0002243] <3>(0|0) (0|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
Tubby C-terminal domain-like0Direct
GDNF receptor-like0.0008341Direct
Frizzled cysteine-rich domain0.001066Inherited
Notch domain0.002789Inherited
GAF domain-like0.006162Inherited
E2F-DP heterodimerization region0.01107Inherited
Orange domain-like0.01107Inherited
Clc chloride channel0.01742Inherited
HLH, helix-loop-helix DNA-binding domain0.05881Inherited
CBS-domain pair0.07095Inherited
Growth factor receptor domain0.116Inherited
Family A G protein-coupled receptor-like0.1533Inherited
Second domain of FERM0.1628Inherited
HD-domain/PDEase-like0.1686Inherited
Cystine-knot cytokines0.2402Inherited
Cyclin-like0.3027Inherited
Sema domain0.3196Inherited
HMG-box0.343Inherited
PDZ domain-like0.4124Inherited
Cadherin-like0.4798Inherited
Plexin repeat0.5126Inherited
lambda repressor-like DNA-binding domains0.8028Inherited
Nicotinic receptor ligand binding domain-like0.829Inherited
Neurotransmitter-gated ion-channel transmembrane pore0.829Inherited
SH3-domain0.8817Inherited
EGF/Laminin0.9253Inherited


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Family

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SCOP termFDR (all)Annotation (direct or inherited)
Retinoblastoma tumor suppressor domains0Direct
Neurotrophin0Direct
Transcriptional factor tubby, C-terminal domain0Direct
L domain0.00004062Direct
Paired domain0.0003044Direct
GDNF receptor-like0.0005705Direct
Frizzled cysteine-rich domain0.0008397Direct
Notch domain0.002019Inherited
Growth factor receptor domain0.002377Inherited
Adenylyl and guanylyl cyclase catalytic domain0.004345Inherited
E2F dimerization segment0.004636Inherited
GAF domain0.004636Inherited
DIX domain0.004636Inherited
DEP domain0.007792Inherited
Hairy Orange domain0.008571Inherited
Clc chloride channel0.01379Inherited
Cell cycle transcription factor e2f-dp0.02053Inherited
HLH, helix-loop-helix DNA-binding domain0.04631Inherited
CBS-domain pair0.04906Inherited
cAMP-binding domain0.0596Inherited
Calmodulin-like0.07692Inherited
Rhodopsin-like0.09479Inherited
PDEase0.12Inherited
Cadherin0.2075Inherited
Motor proteins0.2835Inherited
Sema domain0.2873Inherited
POU-specific domain0.3085Inherited
HMG-box0.3085Inherited
EGF-type module0.3371Inherited
Rel/Dorsal transcription factors, DNA-binding domain0.3755Inherited
NF-kappa-B/REL/DORSAL transcription factors, C-terminal domain0.3755Inherited
PDZ domain0.4289Inherited
Extracellular domain of cell surface receptors0.4587Inherited
Plexin repeat0.4811Inherited
Neurotransmitter-gated ion-channel transmembrane pore0.8073Inherited
Nicotinic receptor ligand binding domain-like0.8073Inherited
SH3-domain0.8666Inherited
Laminin-type module1Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Tubby C-terminal domain-like0Direct
GDNF receptor-like0.0004511Direct
Frizzled cysteine-rich domain0.0005842Direct
Notch domain0.001612Inherited
Nucleotide cyclase0.003201Inherited
GAF domain-like0.003734Inherited
Orange domain-like0.006972Inherited
E2F-DP heterodimerization region0.006972Inherited
Clc chloride channel0.01135Inherited
HLH, helix-loop-helix DNA-binding domain0.04222Inherited
CBS-domain pair0.05194Inherited
Growth factor receptor domain0.08918Inherited
Family A G protein-coupled receptor-like0.1216Inherited
Second domain of FERM0.1299Inherited
HD-domain/PDEase-like0.1349Inherited
"Winged helix" DNA-binding domain0.2005Inherited
Cystine-knot cytokines0.2007Inherited
Cyclin-like0.2594Inherited
Sema domain0.2755Inherited
HMG-box0.2977Inherited
L domain-like0.3167Inherited
PDZ domain-like0.3655Inherited
Cadherin-like0.4322Inherited
Plexin repeat0.4652Inherited
lambda repressor-like DNA-binding domains0.7681Inherited
Nicotinic receptor ligand binding domain-like0.7963Inherited
Neurotransmitter-gated ion-channel transmembrane pore0.7963Inherited
SH3-domain0.8534Inherited
EGF/Laminin0.9009Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
57184,52058
  • 57184 - Growth factor receptor domain
  • 52058 - L domain-like
  • 0.00002826Direct
    52058,57184
  • 52058 - L domain-like
  • 57184 - Growth factor receptor domain
  • 0.00002826Direct
    56112,55073
  • 56112 - Protein kinase-like (PK-like)
  • 55073 - Nucleotide cyclase
  • 0.0006162Direct
    57184,49265
  • 57184 - Growth factor receptor domain
  • 49265 - Fibronectin type III
  • 0.001612Inherited
    55781,55781
  • 55781 - GAF domain-like
  • 55781 - GAF domain-like
  • 0.003734Inherited
    55781,109604
  • 55781 - GAF domain-like
  • 109604 - HD-domain/PDEase-like
  • 0.003734Inherited
    47459,158457
  • 47459 - HLH, helix-loop-helix DNA-binding domain
  • 158457 - Orange domain-like
  • 0.006972Inherited
    46785,144074
  • 46785 - "Winged helix" DNA-binding domain
  • 144074 - E2F-DP heterodimerization region
  • 0.006972Inherited
    52058,48726
  • 52058 - L domain-like
  • 48726 - Immunoglobulin
  • 0.008872Inherited
    49313,49313
  • 49313 - Cadherin-like
  • 49313 - Cadherin-like
  • 0.2426Inherited
    57196,57184
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 0.2426Inherited
    101912,103575
  • 101912 - Sema domain
  • 103575 - Plexin repeat
  • 0.2755Inherited
    50156,50156
  • 50156 - PDZ domain-like
  • 50156 - PDZ domain-like
  • 0.2977Inherited
    81296,81296
  • 81296 - E set domains
  • 81296 - E set domains
  • 0.2977Inherited
    49417,81296
  • 49417 - p53-like transcription factors
  • 81296 - E set domains
  • 0.3644Inherited
    47413,46689
  • 47413 - lambda repressor-like DNA-binding domains
  • 46689 - Homeodomain-like
  • 0.5703Inherited
    57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.5913Inherited
    57184,57196
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 0.6483Inherited
    63712,90112
  • 63712 - Nicotinic receptor ligand binding domain-like
  • 90112 - Neurotransmitter-gated ion-channel transmembrane pore
  • 0.7963Inherited

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    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    52058,48726,48726
  • 52058 - L domain-like
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 0Direct
    57184,52058,57184
  • 57184 - Growth factor receptor domain
  • 52058 - L domain-like
  • 57184 - Growth factor receptor domain
  • 0Direct
    52058,57184,52058
  • 52058 - L domain-like
  • 57184 - Growth factor receptor domain
  • 52058 - L domain-like
  • 0.00002826Direct
    57184,49899,49899
  • 57184 - Growth factor receptor domain
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.00005039Direct
    57196,57196,57184
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 0.0002786Direct
    49899,57196,57196
  • 49899 - Concanavalin A-like lectins/glucanases
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.00131Inherited
    57184,57196,57196
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.002158Inherited
    55781,55781,109604
  • 55781 - GAF domain-like
  • 55781 - GAF domain-like
  • 109604 - HD-domain/PDEase-like
  • 0.003734Inherited
    49313,49313,49313
  • 49313 - Cadherin-like
  • 49313 - Cadherin-like
  • 49313 - Cadherin-like
  • 0.2426Inherited
    81296,81296,81296
  • 81296 - E set domains
  • 81296 - E set domains
  • 81296 - E set domains
  • 0.2977Inherited
    57196,57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.3655Inherited
    57196,57184,57196
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 0.4466Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
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