SUPERFAMILY 1.75 HMM library and genome assignments server

Superfamily is undergoing a server migration - you are now browsing on the new server. Please contact us if you experience any problems.

Mammalian Phenotype (MP): abnormal digestive system physiology

(show info)

Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Root: MP Hierarchy (mammalian/mouse phenotype from MGI_4.41)

Shortest distance to current term (+ for parents, - for children) MP term [MP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + 2:   mammalian phenotype [MP:0000001] <29>
+ 1:   digestive/alimentary phenotype [MP:0005381] <2>(38|46) (40|19|9)
0:   abnormal digestive system physiology [MP:0001663] <18>(16|16) (17|7|5)
- 1:   abnormal gastrointestinal motility [MP:0011082] <5>(1|0) (1|0|0)
- 1:   abnormal salivary gland physiology [MP:0005310] <5>(0|1) (0|0|0)
- 1:   abnormal defecation [MP:0003866] <4>(0|0) (0|0|0)
- 1:   abnormal digestion [MP:0001664] <4>(2|1) (2|0|0)
- 1:   abnormal intestine physiology [MP:0010155] <4>(9|10) (9|6|4)
- 1:   abnormal exocrine pancreas physiology [MP:0010148] <3>(0|0) (0|0|0)
- 1:   abnormal feces composition [MP:0003868] <2>(0|0) (1|0|0)
- 1:   abnormal gastroesophageal sphincter physiology [MP:0010154] <2>(0|0) (0|0|0)
- 1:   abnormal stomach pH [MP:0008004] <2>(0|0) (0|0|0)
- 1:   gastrointestinal hemorrhage [MP:0000465] <2>(2|2) (2|0|0)
- 1:   abnormal gut flora balance [MP:0010377](2|1) (2|0|0)
- 1:   dysphagia [MP:0003158](0|0) (0|0|0)
- 1:   esophageal inflammation [MP:0003278](0|0) (0|0|0)
- 1:   meteorism [MP:0009247](1|1) (1|0|0)
- 1:   palate inflammation [MP:0003767](0|0) (0|0|0)
- 1:   peritoneal inflammation [MP:0003303](0|0) (0|0|0)
- 1:   stomach inflammation [MP:0001873](0|0) (0|0|0)
- 1:   stomatitis [MP:0003746](0|0) (0|0|0)


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Superfamily

(show details)
SCOP termFDR (all)Annotation (direct or inherited)
N-acetylmuramoyl-L-alanine amidase-like0Direct
Nitric oxide (NO) synthase oxygenase domain0Direct
SpoIIaa-like0.0001134Direct
Integrin beta tail domain0.0007816Direct
4-helical cytokines0.001429Inherited
Toll/Interleukin receptor TIR domain0.002192Inherited
Family A G protein-coupled receptor-like0.003987Inherited
SEA domain0.01351Inherited
MFS general substrate transporter0.03601Inherited
RNI-like0.09236Inherited
Ferredoxin reductase-like, C-terminal NADP-linked domain0.09969Inherited
Riboflavin synthase domain-like0.09969Inherited
Rhodanese/Cell cycle control phosphatase0.1091Inherited
DEATH domain0.1218Inherited
Nuclear receptor ligand-binding domain0.5291Inherited
Homeodomain-like1Inherited


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

(show details)
SCOP termFDR (all)Annotation (direct or inherited)
N-acetylmuramoyl-L-alanine amidase-like0Direct
Nitric oxide (NO) synthase oxygenase domain0Direct
Interleukin 17F, IL-17F0.0000482Direct
Cytochrome p450 reductase N-terminal domain-like0.0004334Direct
Pyrin domain, PYD0.0005793Direct
Integrin beta tail domain0.0005793Direct
Interferons/interleukin-10 (IL-10)0.002263Inherited
Toll/Interleukin receptor TIR domain0.006473Inherited
28-residue LRR0.02514Inherited
Cell cycle control phosphatase, catalytic domain0.03055Inherited
Papain-like0.04978Inherited
ABC transporter ATPase domain-like0.08093Inherited
Caspase recruitment domain, CARD0.2969Inherited
Nuclear receptor ligand-binding domain0.5068Inherited
Nuclear receptor0.5917Inherited
Homeodomain1Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
Plot tree as:   Download Newick format tree:
(show help)

Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

(show details)
Supra-domain (Single) FDR (all) Annotation (direct or inherited)
N-acetylmuramoyl-L-alanine amidase-like0Direct
Nitric oxide (NO) synthase oxygenase domain0Direct
SpoIIaa-like0.00005538Direct
Integrin beta tail domain0.0004209Direct
4-helical cytokines0.0007989Direct
Toll/Interleukin receptor TIR domain0.00125Inherited
Family A G protein-coupled receptor-like0.002352Inherited
SEA domain0.008615Inherited
MFS general substrate transporter0.02478Inherited
RNI-like0.06921Inherited
Riboflavin synthase domain-like0.07518Inherited
Ferredoxin reductase-like, C-terminal NADP-linked domain0.07518Inherited
Rhodanese/Cell cycle control phosphatase0.08326Inherited
DEATH domain0.09404Inherited
Cytochrome P4500.2601Inherited
Nuclear receptor ligand-binding domain0.4819Inherited
Homeodomain-like1Inherited

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
57196,69687
  • 57196 - EGF/Laminin
  • 69687 - Integrin beta tail domain
  • 0.0004209Direct
    52540,90123
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 90123 - ABC transporter transmembrane region
  • 0.005217Inherited
    47986,52540
  • 47986 - DEATH domain
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.07518Inherited
    57440,57440
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 0.07518Inherited
    52058,52058
  • 52058 - L domain-like
  • 52058 - L domain-like
  • 0.1237Inherited
    51045,51045
  • 51045 - WW domain
  • 51045 - WW domain
  • 0.1275Inherited
    57586,57586
  • 57586 - TNF receptor-like
  • 57586 - TNF receptor-like
  • 0.3219Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    57196,57196,69687
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 69687 - Integrin beta tail domain
  • 0.0004209Direct
    57440,57440,57440
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 0.001185Inherited
    52540,90123,52540
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 90123 - ABC transporter transmembrane region
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.005217Inherited
    90123,52540,90123
  • 90123 - ABC transporter transmembrane region
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 90123 - ABC transporter transmembrane region
  • 0.005217Inherited
    57586,57586,57586
  • 57586 - TNF receptor-like
  • 57586 - TNF receptor-like
  • 57586 - TNF receptor-like
  • 0.1275Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
    (show help)