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Mammalian Phenotype (MP): abnormal gametogenesis

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Root: MP Hierarchy (mammalian/mouse phenotype from MGI_4.41)

Shortest distance to current term (+ for parents, - for children) MP term [MP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + 3:   mammalian phenotype [MP:0000001] <29>
+ + 2:   reproductive system phenotype [MP:0005389] <2>(37|56) (46|17|6)
+ 1:   abnormal reproductive system morphology [MP:0002160] <12>(27|44) (36|14|6)
0:   abnormal gametogenesis [MP:0001929] <7>(14|17) (18|2|1)
- 1:   abnormal meiosis [MP:0001930] <11>(3|3) (4|0|0)
- 1:   abnormal spermatogenesis [MP:0001156] <10>(7|11) (10|2|0)
- 1:   abnormal germ cell morphology [MP:0002208] <5>(11|10) (13|1|1)
- 1:   abnormal sperm number [MP:0002673] <3>(2|1) (4|0|0)
- 1:   abnormal oogenesis [MP:0001931] <2>(5|4) (5|0|0)
- 1:   abnormal DNA methylation during gametogenesis [MP:0008878](1|0) (1|0|0)
- 1:   transmission ratio distortion [MP:0004179](0|0) (0|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
SMAD MH1 domain0.000008241Direct
PAZ domain0.0002027Direct
The spindle assembly checkpoint protein mad20.0009018Direct
Nucleic acid-binding proteins0.006606Inherited
SMAD/FHA domain0.009282Inherited
SAICAR synthase-like0.07472Inherited
Tudor/PWWP/MBT0.1275Inherited
Bcl-2 inhibitors of programmed cell death0.1849Inherited
Cystine-knot cytokines0.1937Inherited
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase0.3791Inherited
BAR/IMD domain-like0.3946Inherited
Cysteine-rich DNA binding domain, (DM domain)0.4871Inherited
Nuclear receptor ligand-binding domain0.715Inherited
Fibronectin type III0.9313Inherited


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Family

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SCOP termFDR (all)Annotation (direct or inherited)
SMAD domain0.000004166Direct
SMAD MH1 domain0.000004166Direct
PAZ domain0.0001112Direct
The spindle assembly checkpoint protein mad20.0005256Direct
Single strand DNA-binding domain, SSB0.00073Direct
Gonadodropin/Follitropin0.001863Inherited
Histone lysine methyltransferases0.02419Inherited
Tudor domain0.09478Inherited
Insulin-like0.1474Inherited
Bcl-2 inhibitors of programmed cell death0.1474Inherited
Transforming growth factor (TGF)-beta0.229Inherited
Protein kinases, catalytic subunit0.3658Inherited
Cysteine-rich DNA binding domain, (DM domain)0.4348Inherited
PHD domain0.4642Inherited
Nuclear receptor ligand-binding domain0.6592Inherited
Fibronectin type III0.9003Inherited
I set domains0.9567Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
SMAD MH1 domain0.000003578Direct
PAZ domain0.0001026Direct
The spindle assembly checkpoint protein mad20.0004883Direct
Nucleic acid-binding proteins0.004029Inherited
SMAD/FHA domain0.005778Inherited
dsRNA-binding domain-like0.03567Inherited
SAICAR synthase-like0.05499Inherited
Tudor/PWWP/MBT0.09906Inherited
"Winged helix" DNA-binding domain0.1254Inherited
Insulin-like0.1497Inherited
Bcl-2 inhibitors of programmed cell death0.1497Inherited
Cystine-knot cytokines0.1577Inherited
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase0.3331Inherited
BAR/IMD domain-like0.3482Inherited
Cysteine-rich DNA binding domain, (DM domain)0.4397Inherited
Nuclear receptor ligand-binding domain0.6751Inherited
Fibronectin type III0.9074Inherited
Immunoglobulin1Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
50249,50249
  • 50249 - Nucleic acid-binding proteins
  • 50249 - Nucleic acid-binding proteins
  • 0.001742Inherited
    48726,48726
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 0.8583Inherited

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    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    57667,57667,57667
  • 57667 - beta-beta-alpha zinc fingers
  • 57667 - beta-beta-alpha zinc fingers
  • 57667 - beta-beta-alpha zinc fingers
  • 0.4542Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
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