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Mammalian Phenotype (MP): abnormal postnatal growth/weight/body size

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Root: MP Hierarchy (mammalian/mouse phenotype from MGI_4.41)

Shortest distance to current term (+ for parents, - for children) MP term [MP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + 2:   mammalian phenotype [MP:0000001] <29>
+ 1:   growth/size/body region phenotype [MP:0005378] <12>(64|94) (71|47|27)
0:   abnormal postnatal growth/weight/body size [MP:0002089] <3>(37|51) (41|31|14)
- 1:   abnormal body size [MP:0003956] <5>(27|40) (30|19|7)
- 1:   abnormal lean body mass [MP:0003959] <2>(6|7) (7|5|4)
- 1:   abnormal postnatal growth [MP:0001731] <2>(5|12) (6|6|3)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
Amyloid beta a4 protein copper binding domain (domain 2)0Direct
FtsH protease domain-like0Direct
Guanido kinase N-terminal domain0Direct
ATP-dependent DNA ligase DNA-binding domain0Direct
Assembly domain of cartilage oligomeric matrix protein0Direct
Nitric oxide (NO) synthase oxygenase domain0Direct
DNA ligase/mRNA capping enzyme, catalytic domain0Direct
Notch domain0Direct
Aromatic aminoacid monoxygenases, catalytic and oligomerization domains0Direct
JAB1/MPN domain0Direct
N-acetylmuramoyl-L-alanine amidase-like0Direct
Glutamine synthetase/guanido kinase0Direct
p53 tetramerization domain0Direct
Nuclear receptor coactivator interlocking domain0Direct
CAPPD, an extracellular domain of amyloid beta A4 protein0Direct
A heparin-binding domain0Direct
SRF-like0Direct
Ferredoxin reductase-like, C-terminal NADP-linked domain0.002195Inherited
Riboflavin synthase domain-like0.002195Inherited
Flavoproteins0.005724Inherited
KA1-like0.0129Inherited
Transcription factor STAT-4 N-domain0.04053Inherited
STAT0.04053Inherited
Macro domain-like0.06062Inherited
SH2 domain0.07569Inherited
Chromo domain-like0.08782Inherited
4-helical cytokines0.09955Inherited
ENTH/VHS domain0.1709Inherited
Hormone receptor domain0.2011Inherited
YWTD domain0.2367Inherited
Hect, E3 ligase catalytic domain0.4865Inherited
GroEL equatorial domain-like0.5349Inherited
GroEL apical domain-like0.5349Inherited
Family A G protein-coupled receptor-like0.5734Inherited
Acid proteases0.7348Inherited
L domain-like0.9043Inherited
Clathrin adaptor appendage domain0.9364Inherited


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

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SCOP termFDR (all)Annotation (direct or inherited)
DNA ligase/mRNA capping enzyme postcatalytic domain0Direct
PAS domain of steroid receptor coactivator 1A, NCo-A10Direct
Retinoblastoma tumor suppressor domains0Direct
Amyloid beta a4 protein copper binding domain (domain 2)0Direct
SRF-like0Direct
ATP-dependent DNA ligase catalytic domain0Direct
Nitric oxide (NO) synthase oxygenase domain0Direct
RUNT domain0Direct
p53 DNA-binding domain-like0Direct
Nuclear receptor coactivator interlocking domain0Direct
CPH domain0Direct
Eps15 homology domain (EH domain)0Direct
Phenylalanine metabolism regulatory domain0Direct
Inositol polyphosphate 5-phosphatase (IPP5)0Direct
Assembly domain of cartilage oligomeric matrix protein0Direct
Notch domain0Direct
A heparin-binding domain0Direct
p53 tetramerization domain0Direct
Aromatic aminoacid monoxygenases, catalytic and oligomerization domains0Direct
N-acetylmuramoyl-L-alanine amidase-like0Direct
Guanido kinase catalytic domain0Direct
CAPPD, an extracellular domain of amyloid beta A4 protein0Direct
IP3 receptor type 1 binding core, domain 20Direct
NADPH-cytochrome p450 reductase FAD-binding domain-like0Direct
FtsH protease domain-like0Direct
Neurotrophin0Direct
Cytochrome p450 reductase N-terminal domain-like0Direct
Guanido kinase N-terminal domain0Direct
NADPH-cytochrome p450 reductase-like0Direct
Hexokinase0Direct
Phoshoinositide 3-kinase (PI3K), catalytic domain0.00001934Direct
Paired domain0.0007505Direct
Phoshoinositide 3-kinase (PI3K) helical domain0.004272Inherited
Pepsin-like0.02213Inherited
Chromo domain0.02379Inherited
STAT0.03281Inherited
L domain0.03281Inherited
Transcription factor STAT-4 N-domain0.03281Inherited
STAT DNA-binding domain0.03281Inherited
Macro domain0.04908Inherited
Kinase associated domain 1, KA10.04908Inherited
SH2 domain0.08096Inherited
Hormone receptor domain0.1768Inherited
YWTD domain0.2109Inherited
NF-kappa-B/REL/DORSAL transcription factors, C-terminal domain0.3535Inherited
VHS domain0.4234Inherited
Rel/Dorsal transcription factors, DNA-binding domain0.4542Inherited
Hect, E3 ligase catalytic domain0.4628Inherited
gamma-adaptin C-terminal appendage domain-like0.5045Inherited
Rhodopsin-like0.5768Inherited
DEP domain0.7118Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
SRF-like0Direct
CAPPD, an extracellular domain of amyloid beta A4 protein0Direct
p53 tetramerization domain0Direct
DNA ligase/mRNA capping enzyme, catalytic domain0Direct
Nuclear receptor coactivator interlocking domain0Direct
Glutamine synthetase/guanido kinase0Direct
Guanido kinase N-terminal domain0Direct
Assembly domain of cartilage oligomeric matrix protein0Direct
JAB1/MPN domain0Direct
Notch domain0Direct
Nitric oxide (NO) synthase oxygenase domain0Direct
A heparin-binding domain0Direct
FtsH protease domain-like0Direct
Aromatic aminoacid monoxygenases, catalytic and oligomerization domains0Direct
Amyloid beta a4 protein copper binding domain (domain 2)0Direct
N-acetylmuramoyl-L-alanine amidase-like0Direct
ATP-dependent DNA ligase DNA-binding domain0Direct
Riboflavin synthase domain-like0.001252Inherited
Ferredoxin reductase-like, C-terminal NADP-linked domain0.001252Inherited
Flavoproteins0.003452Inherited
FabD/lysophospholipase-like0.006282Inherited
KA1-like0.00821Inherited
Transcription factor STAT-4 N-domain0.02818Inherited
STAT0.02818Inherited
Macro domain-like0.0437Inherited
SH2 domain0.05573Inherited
Chromo domain-like0.06549Inherited
4-helical cytokines0.0751Inherited
ENTH/VHS domain0.137Inherited
Hormone receptor domain0.1643Inherited
YWTD domain0.1974Inherited
GAT-like domain0.4072Inherited
Hect, E3 ligase catalytic domain0.4389Inherited
GroEL equatorial domain-like0.4879Inherited
GroEL apical domain-like0.4879Inherited
Family A G protein-coupled receptor-like0.5269Inherited
Acid proteases0.696Inherited
CAD & PB1 domains0.7588Inherited
TNF-like0.8748Inherited
L domain-like0.8778Inherited
Clathrin adaptor appendage domain0.9133Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
90193,90193
  • 90193 - Notch domain
  • 90193 - Notch domain
  • 0Direct
    56491,89811
  • 56491 - A heparin-binding domain
  • 89811 - Amyloid beta a4 protein copper binding domain (domain 2)
  • 0Direct
    48034,55931
  • 48034 - Guanido kinase N-terminal domain
  • 55931 - Glutamine synthetase/guanido kinase
  • 0Direct
    52518,52518
  • 52518 - Thiamin diphosphate-binding fold (THDP-binding)
  • 52518 - Thiamin diphosphate-binding fold (THDP-binding)
  • 0Direct
    57196,57424
  • 57196 - EGF/Laminin
  • 57424 - LDL receptor-like module
  • 0Direct
    54637,54637
  • 54637 - Thioesterase/thiol ester dehydrase-isomerase
  • 54637 - Thioesterase/thiol ester dehydrase-isomerase
  • 0Direct
    49265,53300
  • 49265 - Fibronectin type III
  • 53300 - vWA-like
  • 0Direct
    56091,50249
  • 56091 - DNA ligase/mRNA capping enzyme, catalytic domain
  • 50249 - Nucleic acid-binding proteins
  • 0Direct
    49417,47719
  • 49417 - p53-like transcription factors
  • 47719 - p53 tetramerization domain
  • 0Direct
    55021,56534
  • 55021 - ACT-like
  • 56534 - Aromatic aminoacid monoxygenases, catalytic and oligomerization domains
  • 0Direct
    64268,103657
  • 64268 - PX domain
  • 103657 - BAR/IMD domain-like
  • 0Direct
    57196,90193
  • 57196 - EGF/Laminin
  • 90193 - Notch domain
  • 0Direct
    117018,56091
  • 117018 - ATP-dependent DNA ligase DNA-binding domain
  • 56091 - DNA ligase/mRNA capping enzyme, catalytic domain
  • 0Direct
    52540,140990
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 140990 - FtsH protease domain-like
  • 0Direct
    54236,57889
  • 54236 - Ubiquitin-like
  • 57889 - Cysteine-rich domain
  • 0Direct
    81324,53850
  • 81324 - Voltage-gated potassium channels
  • 53850 - Periplasmic binding protein-like II
  • 0Direct
    49562,48371
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 48371 - ARM repeat
  • 0.003452Inherited
    48371,56112
  • 48371 - ARM repeat
  • 56112 - Protein kinase-like (PK-like)
  • 0.006282Inherited
    52058,57184
  • 52058 - L domain-like
  • 57184 - Growth factor receptor domain
  • 0.02818Inherited
    48092,47655
  • 48092 - Transcription factor STAT-4 N-domain
  • 47655 - STAT
  • 0.02818Inherited
    57184,52058
  • 57184 - Growth factor receptor domain
  • 52058 - L domain-like
  • 0.02818Inherited
    47655,49417
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 0.02818Inherited
    49417,55550
  • 49417 - p53-like transcription factors
  • 55550 - SH2 domain
  • 0.02818Inherited
    111418,81321
  • 111418 - Hormone receptor domain
  • 81321 - Family A G protein-coupled receptor-like
  • 0.05702Inherited
    46966,46966
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 0.07875Inherited
    57424,57424
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 0.1141Inherited
    54160,52540
  • 54160 - Chromo domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.182Inherited
    63825,57196
  • 63825 - YWTD domain
  • 57196 - EGF/Laminin
  • 0.2834Inherited
    48464,89009
  • 48464 - ENTH/VHS domain
  • 89009 - GAT-like domain
  • 0.4072Inherited
    49417,81296
  • 49417 - p53-like transcription factors
  • 81296 - E set domains
  • 0.4334Inherited
    57440,50494
  • 57440 - Kringle-like
  • 50494 - Trypsin-like serine proteases
  • 0.7704Inherited

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    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    49265,49265,53300
  • 49265 - Fibronectin type III
  • 49265 - Fibronectin type III
  • 53300 - vWA-like
  • 0Direct
    117018,56091,50249
  • 117018 - ATP-dependent DNA ligase DNA-binding domain
  • 56091 - DNA ligase/mRNA capping enzyme, catalytic domain
  • 50249 - Nucleic acid-binding proteins
  • 0Direct
    63825,57196,57424
  • 63825 - YWTD domain
  • 57196 - EGF/Laminin
  • 57424 - LDL receptor-like module
  • 0Direct
    57850,49599,49599
  • 57850 - RING/U-box
  • 49599 - TRAF domain-like
  • 49599 - TRAF domain-like
  • 0Direct
    57196,90193,90193
  • 57196 - EGF/Laminin
  • 90193 - Notch domain
  • 90193 - Notch domain
  • 0Direct
    57196,57424,57424
  • 57196 - EGF/Laminin
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 0Direct
    49562,48371,56112
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 48371 - ARM repeat
  • 56112 - Protein kinase-like (PK-like)
  • 0.003452Inherited
    47655,49417,55550
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 55550 - SH2 domain
  • 0.02818Inherited
    52058,57184,52058
  • 52058 - L domain-like
  • 57184 - Growth factor receptor domain
  • 52058 - L domain-like
  • 0.02818Inherited
    48092,47655,49417
  • 48092 - Transcription factor STAT-4 N-domain
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 0.02818Inherited
    57424,57424,57424
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 0.1141Inherited
    54160,54160,52540
  • 54160 - Chromo domain-like
  • 54160 - Chromo domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.182Inherited
    54160,52540,52540
  • 54160 - Chromo domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.182Inherited
    57196,57184,57184
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 57184 - Growth factor receptor domain
  • 0.4072Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
    (show help)