SUPERFAMILY 1.75 HMM library and genome assignments server

Superfamily is undergoing a server migration - you are now browsing on the new server. Please contact us if you experience any problems.

Mammalian Phenotype (MP): abnormal skeleton development

(show info)

Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Root: MP Hierarchy (mammalian/mouse phenotype from MGI_4.41)

Shortest distance to current term (+ for parents, - for children) MP term [MP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + 3:   mammalian phenotype [MP:0000001] <29>
+ + 2:   skeleton phenotype [MP:0005390] <2>(46|63) (50|41|26)
+ 1:   abnormal skeleton morphology [MP:0005508] <15>(41|59) (47|38|25)
0:   abnormal skeleton development [MP:0002113] <13>(6|14) (6|5|2)
- 1:   abnormal cartilage development [MP:0000164] <4>(2|2) (2|3|2)
- 1:   abnormal vertebrae development [MP:0005225] <4>(0|0) (0|1|0)
- 1:   abnormal chondrocyte differentiation [MP:0014105] <2>(0|0) (0|0|0)
- 1:   abnormal epiphyseal plate morphology [MP:0006395] <2>(2|4) (2|4|2)
- 1:   abnormal long bone epiphysis morphology [MP:0000131] <2>(0|0) (0|0|0)
- 1:   abnormal osteoblast differentiation [MP:0008395] <2>(0|0) (0|0|0)
- 1:   abnormal osteoid morphology [MP:0010924] <2>(0|0) (0|0|0)
- 1:   abnormal fontanelle morphology [MP:0000084] <1>(1|1) (1|0|0)
- 1:   abnormal ossification involved in bone maturation [MP:0011722] <1>(0|0) (0|0|0)
- 1:   abnormal sclerotome morphology [MP:0006029] <1>(0|0) (0|0|0)
- 1:   abnormal osteoclast differentiation [MP:0008396](0|1) (0|0|0)
- 1:   abnormal rib development [MP:0002823](1|1) (1|0|0)
- 1:   chondrodystrophy [MP:0002657](1|1) (1|0|0)


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Superfamily

(show details)
SCOP termFDR (all)Annotation (direct or inherited)
Nitric oxide (NO) synthase oxygenase domain0Direct
PGBD-like0.01295Inherited
Metalloproteases ("zincins"), catalytic domain0.02873Inherited
Cystine-knot cytokines0.05473Inherited
Homeodomain-like0.1738Inherited
HMG-box0.2598Inherited


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

(show details)
SCOP termFDR (all)Annotation (direct or inherited)
Nitric oxide (NO) synthase oxygenase domain0Direct
RUNT domain0Direct
Cytochrome p450 reductase N-terminal domain-like0.0001641Direct
beta-glycanases0.0001641Direct
NADPH-cytochrome p450 reductase-like0.0006108Direct
NADPH-cytochrome p450 reductase FAD-binding domain-like0.0006108Direct
MMP N-terminal domain0.01032Inherited
Matrix metalloproteases, catalytic domain0.01032Inherited
Arylsulfatase0.02534Inherited
Long-chain cytokines0.02913Inherited
Homeodomain0.128Inherited
Transforming growth factor (TGF)-beta0.1615Inherited
Rel/Dorsal transcription factors, DNA-binding domain0.1754Inherited
HMG-box0.2475Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
Plot tree as:   Download Newick format tree:
(show help)

Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

(show details)
Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Nitric oxide (NO) synthase oxygenase domain0Direct
PGBD-like0.008235Inherited
Metalloproteases ("zincins"), catalytic domain0.01943Inherited
Cystine-knot cytokines0.03898Inherited
Homeodomain-like0.1396Inherited
HMG-box0.2188Inherited

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
47090,55486
  • 47090 - PGBD-like
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 0.008235Inherited
    55486,50923
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 50923 - Hemopexin-like domain
  • 0.05252Inherited
    57603,57603
  • 57603 - FnI-like domain
  • 57603 - FnI-like domain
  • 0.05252Inherited
    57424,57424
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 0.09989Inherited
    49417,81296
  • 49417 - p53-like transcription factors
  • 81296 - E set domains
  • 0.1569Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    47090,55486,50923
  • 47090 - PGBD-like
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 50923 - Hemopexin-like domain
  • 0.05252Inherited
    57424,57424,57424
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 0.09989Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
    (show help)