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Mammalian Phenotype (MP): abnormal kidney physiology

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Root: MP Hierarchy (mammalian/mouse phenotype from MGI_4.41)

Shortest distance to current term (+ for parents, - for children) MP term [MP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + 3:   mammalian phenotype [MP:0000001] <29>
+ + 2:   renal/urinary system phenotype [MP:0005367] <2>(41|47) (46|26|11)
+ 1:   abnormal renal/urinary system physiology [MP:0005502] <6>(20|21) (25|10|1)
0:   abnormal kidney physiology [MP:0002136] <22>(12|15) (14|5|1)
- 1:   abnormal renal reabsorbtion [MP:0010107] <6>(2|2) (3|0|0)
- 1:   kidney inflammation [MP:0001859] <5>(1|3) (2|2|0)
- 1:   abnormal kidney apoptosis [MP:0011367] <2>(4|4) (4|0|0)
- 1:   abnormal kidney cell proliferation [MP:0011439] <2>(1|1) (1|1|1)
- 1:   abnormal kidney glutathione peroxidase activity [MP:0012576] <2>(0|0) (0|0|0)
- 1:   abnormal podocyte physiology [MP:0011863] <2>(0|0) (0|0|0)
- 1:   abnormal renal filtration [MP:0013285] <2>(0|0) (0|1|0)
- 1:   abnormal renal plasma flow rate [MP:0005524] <2>(0|0) (0|0|0)
- 1:   abnormal renal sympathetic nerve activity [MP:0004050] <2>(0|0) (0|0|0)
- 1:   abnormal renal transport [MP:0011417] <2>(1|1) (1|0|0)
- 1:   abnormal renal vascular resistance [MP:0005529] <2>(0|0) (0|0|0)
- 1:   abnormal tubuloglomerular feedback response [MP:0011295] <2>(0|0) (0|0|0)
- 1:   altered susceptibility to kidney reperfusion injury [MP:0004040] <2>(3|3) (3|1|0)
- 1:   abnormal renal water homeostasis [MP:0011444] <1>(1|1) (1|0|0)
- 1:   kidney hemorrhage [MP:0000533] <1>(0|0) (0|0|0)
- 1:   abnormal kidney epithelial cell primary cilium physiology [MP:0011744](0|0) (0|0|0)
- 1:   isosthenuria [MP:0013305](0|0) (0|0|0)
- 1:   kidney failure [MP:0003606](0|0) (0|0|0)
- 1:   nephrolithiasis [MP:0002708](0|0) (0|0|0)
- 1:   renal ischemia [MP:0011758](0|0) (0|0|0)
- 1:   renal tubular acidosis [MP:0000525](0|0) (0|0|0)
- 1:   vesicoureteral reflux [MP:0001948](0|0) (0|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
Nitric oxide (NO) synthase oxygenase domain0Direct
Ferredoxin reductase-like, C-terminal NADP-linked domain0.0001292Direct
Riboflavin synthase domain-like0.0001292Direct
Toll/Interleukin receptor TIR domain0.0001847Direct
Flavoproteins0.002395Inherited
L30e-like0.003986Inherited
Plexin repeat0.03759Inherited
Sema domain0.04889Inherited
Aquaporin-like0.1063Inherited
Clc chloride channel0.2817Inherited
Growth factor receptor domain0.4819Inherited
CBS-domain pair0.5192Inherited


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Family

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SCOP termFDR (all)Annotation (direct or inherited)
Nitric oxide (NO) synthase oxygenase domain0Direct
Anion transport protein, cytoplasmic domain0.0000217Direct
Cytochrome p450 reductase N-terminal domain-like0.00009646Direct
Toll/Interleukin receptor TIR domain0.00009958Direct
NADPH-cytochrome p450 reductase FAD-binding domain-like0.0003698Direct
NADPH-cytochrome p450 reductase-like0.0003698Direct
Short-chain cytokines0.01546Inherited
Plexin repeat0.03225Inherited
Sema domain0.04179Inherited
Aquaporin-like0.09554Inherited
PLC-like (P variant)0.09554Inherited
Noncollagenous (NC1) domain of collagen IV0.2633Inherited
Clc chloride channel0.2633Inherited
I set domains0.5031Inherited
CBS-domain pair0.5057Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Nitric oxide (NO) synthase oxygenase domain0Direct
Riboflavin synthase domain-like0.00006378Direct
Ferredoxin reductase-like, C-terminal NADP-linked domain0.00006378Direct
Toll/Interleukin receptor TIR domain0.00009304Direct
Flavoproteins0.001372Inherited
L30e-like0.00235Inherited
TNF receptor-like0.01068Inherited
Plexin repeat0.02598Inherited
Sema domain0.03448Inherited
Aquaporin-like0.08088Inherited
Clc chloride channel0.2396Inherited
Growth factor receptor domain0.4342Inherited
CBS-domain pair0.4717Inherited
MFS general substrate transporter0.9988Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
52799,49562
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 0.0007064Direct
    57586,57586
  • 57586 - TNF receptor-like
  • 57586 - TNF receptor-like
  • 0.009859Inherited
    101912,103575
  • 101912 - Sema domain
  • 103575 - Plexin repeat
  • 0.03448Inherited
    50044,55550
  • 50044 - SH3-domain
  • 55550 - SH2 domain
  • 0.2787Inherited
    48726,48726
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 0.634Inherited

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    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    48726,48726,48726
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 0.5178Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
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