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Mammalian Phenotype (MP): abnormal germ cell morphology

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Root: MP Hierarchy (mammalian/mouse phenotype from MGI_4.41)

Shortest distance to current term (+ for parents, - for children) MP term [MP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + 3:   reproductive system phenotype [MP:0005389] <2>(37|56) (46|17|6)
+ + + 3:   mammalian phenotype [MP:0000001] <29>
+ + 2:   abnormal reproductive system morphology [MP:0002160] <12>(27|44) (36|14|6)
+ + 2:   cellular phenotype [MP:0005384] <6>(96|116) (103|56|31)
+ 1:   abnormal gametogenesis [MP:0001929] <7>(14|17) (18|2|1)
+ 1:   abnormal cell morphology [MP:0000358] <12>(19|17) (22|8|2)
0:   abnormal germ cell morphology [MP:0002208] <5>(11|10) (13|1|1)
- 1:   abnormal male germ cell morphology [MP:0006362] <5>(7|6) (9|1|0)
- 1:   abnormal gametes [MP:0001124] <4>(5|4) (7|0|0)
- 1:   decreased germ cell number [MP:0002209] <4>(8|9) (11|1|0)
- 1:   abnormal female germ cell morphology [MP:0006361] <3>(4|3) (4|0|0)
- 1:   abnormal primordial germ cell morphology [MP:0008391] <2>(2|2) (2|0|1)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
SMAD MH1 domain0.000002494Direct
PAZ domain0.00007928Direct
Bcl-2 inhibitors of programmed cell death0.003619Inherited
SMAD/FHA domain0.009747Inherited
Cystine-knot cytokines0.01115Inherited
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase0.01838Inherited
Nuclear receptor ligand-binding domain0.05565Inherited
The spindle assembly checkpoint protein mad20.1738Inherited
Tudor/PWWP/MBT0.1901Inherited
Nucleic acid-binding proteins0.2192Inherited
BAR/IMD domain-like0.2769Inherited


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Family

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SCOP termFDR (all)Annotation (direct or inherited)
SMAD domain0.000001099Direct
SMAD MH1 domain0.000001099Direct
PAZ domain0.00003814Direct
Transforming growth factor (TGF)-beta0.001136Inherited
Insulin-like0.00126Inherited
Bcl-2 inhibitors of programmed cell death0.002113Inherited
Nuclear receptor ligand-binding domain0.03965Inherited
Single strand DNA-binding domain, SSB0.08575Inherited
The spindle assembly checkpoint protein mad20.1411Inherited
Tudor domain0.287Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
SMAD MH1 domain0.000001044Direct
PAZ domain0.00003795Direct
Insulin-like0.001255Inherited
Bcl-2 inhibitors of programmed cell death0.002124Inherited
SMAD/FHA domain0.006084Inherited
Cystine-knot cytokines0.007037Inherited
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase0.01201Inherited
Nuclear receptor ligand-binding domain0.03973Inherited
The spindle assembly checkpoint protein mad20.1396Inherited
Tudor/PWWP/MBT0.1543Inherited
Nucleic acid-binding proteins0.1811Inherited
dsRNA-binding domain-like0.2085Inherited
BAR/IMD domain-like0.2351Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
50249,50249
  • 50249 - Nucleic acid-binding proteins
  • 50249 - Nucleic acid-binding proteins
  • 0.1396Inherited

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    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    57667,57667,57667
  • 57667 - beta-beta-alpha zinc fingers
  • 57667 - beta-beta-alpha zinc fingers
  • 57667 - beta-beta-alpha zinc fingers
  • 0.1354Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
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