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Mammalian Phenotype (MP): abnormal macrophage morphology

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Root: MP Hierarchy (mammalian/mouse phenotype from MGI_4.41)

Shortest distance to current term (+ for parents, - for children) MP term [MP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + + + 6:   hematopoietic system phenotype [MP:0005397] <2>(72|102) (78|63|30)
+ + + + + 5:   abnormal hematopoietic system morphology/development [MP:0002396] <5>(58|86) (66|47|21)
+ + + + + 5:   mammalian phenotype [MP:0000001] <29>
+ + + + 4:   immune system phenotype [MP:0005387] <2>(76|114) (86|66|35)
+ + + + 4:   abnormal myeloid cell morphology [MP:0013658] <8>(19|41) (26|23|8)
+ + + + 4:   abnormal hematopoietic cell morphology [MP:0013656] <9>(49|77) (60|43|18)
+ + + 3:   abnormal immune system morphology [MP:0000685] <3>(51|76) (60|35|18)
+ + + 3:   abnormal myeloid leukocyte morphology [MP:0008250] <2>(11|24) (16|10|2)
+ + + 3:   abnormal leukocyte morphology [MP:0008246] <4>(37|62) (47|29|15)
+ + 2:   abnormal immune system cell morphology [MP:0000716] <5>(38|63) (48|29|16)
+ + 2:   abnormal phagocyte morphology [MP:0008251] <3>(10|21) (13|9|1)
+ + 2:   abnormal mononuclear cell morphology [MP:0008247] <2>(34|57) (41|28|14)
+ 1:   abnormal mononuclear phagocyte morphology [MP:0008248] <3>(6|14) (8|5|0)
+ 1:   abnormal professional antigen presenting cell morphology [MP:0008195] <3>(17|32) (20|11|5)
0:   abnormal macrophage morphology [MP:0002446] <14>(6|12) (8|4|0)
- 1:   abnormal microglial cell morphology [MP:0000136] <3>(0|0) (0|0|0)
- 1:   abnormal macrophage cell number [MP:0020202] <2>(5|7) (5|1|0)
- 1:   abnormal osteoclast morphology [MP:0004982] <2>(4|7) (6|1|0)
- 1:   increased macrophage cell number [MP:0005425] <2>(4|4) (4|0|0)
- 1:   abnormal alveolar macrophage morphology [MP:0008245] <1>(0|0) (0|0|0)
- 1:   abnormal macrophage derived foam cell morphology [MP:0008243] <1>(0|0) (0|0|0)
- 1:   decreased macrophage cell number [MP:0003884] <1>(0|0) (0|0|0)
- 1:   abnormal Kupffer cell morphology [MP:0008114](0|0) (0|0|0)
- 1:   abnormal macrophage differentiation [MP:0008113](0|0) (0|0|0)
- 1:   abnormal melanophage morphology [MP:0020334](0|0) (0|0|0)
- 1:   abnormal metallophilic macrophage morphology [MP:0008241](0|0) (0|0|0)
- 1:   abnormal peritoneal macrophage morphology [MP:0008244](0|0) (0|0|0)
- 1:   abnormal perivascular macrophage morphology [MP:0008242](0|0) (0|0|0)
- 1:   abnormal spleen marginal zone macrophage morphology [MP:0008240](0|0) (0|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
Nitric oxide (NO) synthase oxygenase domain0Direct
Triple coiled coil domain of C-type lectins0.0002123Direct
Nuclear receptor ligand-binding domain0.001713Inherited
Flavoproteins0.003299Inherited
Riboflavin synthase domain-like0.01559Inherited
Ferredoxin reductase-like, C-terminal NADP-linked domain0.01559Inherited


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Family

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SCOP termFDR (all)Annotation (direct or inherited)
Nitric oxide (NO) synthase oxygenase domain0Direct
beta-glycanases0.0001272Direct
Triple coiled coil domain of C-type lectins0.0001272Direct
Cytochrome p450 reductase N-terminal domain-like0.0001272Direct
NADPH-cytochrome p450 reductase-like0.0004826Direct
NADPH-cytochrome p450 reductase FAD-binding domain-like0.0004826Direct
Tetraspanin0.0004826Direct
Nuclear receptor ligand-binding domain0.001132Inherited
Nuclear receptor0.001132Inherited
NF-kappa-B/REL/DORSAL transcription factors, C-terminal domain0.02458Inherited
Rel/Dorsal transcription factors, DNA-binding domain0.0433Inherited
Long-chain cytokines0.04697Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Nitric oxide (NO) synthase oxygenase domain0Direct
Triple coiled coil domain of C-type lectins0.0001077Direct
Nuclear receptor ligand-binding domain0.0009664Direct
Flavoproteins0.001924Inherited
Glucocorticoid receptor-like (DNA-binding domain)0.0023Inherited
Riboflavin synthase domain-like0.01003Inherited
Ferredoxin reductase-like, C-terminal NADP-linked domain0.01003Inherited
TNF-like0.4144Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
47986,47986
  • 47986 - DEATH domain
  • 47986 - DEATH domain
  • 0.00003735Direct
    57944,56436
  • 57944 - Triple coiled coil domain of C-type lectins
  • 56436 - C-type lectin-like
  • 0.0001077Direct
    57716,48508
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 48508 - Nuclear receptor ligand-binding domain
  • 0.0006927Direct
    49417,81296
  • 49417 - p53-like transcription factors
  • 81296 - E set domains
  • 0.03987Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
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